Aporphine - Wikipedia
Aporphine is an alkaloid with the chemical formula C17H17N. It is the core chemical substructure of the aporphine alkaloids, a ... It can exist in either of two enantiomeric forms, (R)-aporphine and (S)-aporphine. Many different derivatives have been ... R)-Aporphine is a dopamine receptor D1 antagonist with a Ki of 717 nM and a dopamine receptor D2 antagonist with a Ki of 527 nM ... Aporphine natural products occur with either the (R)- or (S)-stereochemistries, or they can be achiral. Furthermore, morphine- ...
Aporphines | Harvard Catalyst Profiles | Harvard Catalyst
"Aporphines" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical Subject ... R-(-)-N-alkyl-11-hydroxy-10-hydroxymethyl- and 10-methyl-aporphines as 5-HT1A receptor ligands. Bioorg Med Chem Lett. 2007 Aug ... This graph shows the total number of publications written about "Aporphines" by people in Harvard Catalyst Profiles by year, ... Identification of fluorinated (R)-(-)-aporphine derivatives as potent and selective ligands at serotonin 5-HT2C receptor. ...
Oxoisoaporphines and aporphines: Versatile molecules with anticancer effects<...
Oxoisoaporphines and aporphines : Versatile molecules with anticancer effects. En: Molecules. 2020 ; Vol. 25, N.º 1. ... Oxoisoaporphines and aporphines: Versatile molecules with anticancer effects. Esteban Rodríguez-Arce, Patricio Cancino, Manuel ... title = "Oxoisoaporphines and aporphines: Versatile molecules with anticancer effects",. abstract = "Cancer is a disease that ... Oxoisoaporphines and aporphines: Versatile molecules with anticancer effects. / Rodríguez-Arce, Esteban; Cancino, Patricio; ...
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Dereplication of Aporphine Alkaloids by UHPLC-HR-ESI-MS/MS and NMR from Duguetia lanceolata St. -Hil (Annonaceae) and ... Additionally, it was also demonstrated the potential of aporphine alkaloids from Duguetia lanceolata St. -Hil (Annonaceae) in ... that were shown to be composed of aporphine alkaloids. 1H NMR analysis and UHPLC-HR-ESI-MS/MS based dereplication allowed the ...
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... dehydro derivatives of such simple aporphines, oxidative derivatives of such simple aporphines, aporphines with an aromatic ... Aporphine and oxoaporphine compounds and pharmaceutical use thereof US20050074510A1 (en) * 2003-10-04. 2005-04-07. Bobrowski ... Aporphine and oxoaporphine compounds and pharmaceutical use thereof US7057044B2 (en) * 2003-04-04. 2006-06-06. Lotus ... Aporphine and oxoaporphine compounds and pharmaceutical use thereof US20050074510A1 (en) * 2003-10-04. 2005-04-07. Bobrowski ...
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Antioxidant and anticancer aporphine alkaloids from the leaves of Nelumbo nucifera Gaertn. cv. Rosa-plena. Molecules. 2014;19: ... Ma C, Wang J, Chu H, Zhang X, Wang Z, Wang H, Li G. Purification and Characterization of Aporphine Alkaloids from Leaves of ... Recent studies have revealed that the major constituents of AELL are aporphine alkaloids [49]. Nuciferine, a vital constituent ... of aporphine alkaloids, had a pharmacologic profile of action associated with arterial relaxation via suppressing extracellular ...
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Aporphines. 48. Enantioselectivity of (R)-(-)- and (S)-(+)-N-n-propylnorapomorphine on dopamine receptors. J Med Chem. 1983 Apr ... Binding of [3H]apomorphine to an aporphine binding site as well as to dopamine sites in tissue from bovine caudate nucleus. ... Aporphines. 39. Synthesis, dopamine receptor binding, and pharmacological activity of (R)-(-)- and (S)-(+)-2-hydroxyapomorphine ... Aporphines, 36. Dopamine receptor interactions of trihydroxyaporphines. Synthesis, radioreceptor binding, and striatal ...
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Alkaloid from phoebe declinata nees leaves<...
abstract = "Introduction: Genus Phoebe have been reported to produce isoquinoline alkaloids as apor-phines, noraporphines, and ... N2 - Introduction: Genus Phoebe have been reported to produce isoquinoline alkaloids as apor-phines, noraporphines, and ... AB - Introduction: Genus Phoebe have been reported to produce isoquinoline alkaloids as apor-phines, noraporphines, and ... Introduction: Genus Phoebe have been reported to produce isoquinoline alkaloids as apor-phines, noraporphines, and ...