We further analyzed the mRNA levels of BCL2L11 (BIM), BAK1, BCL2, BCL2L1 (BCL-XL), and BID, which are apoptosis regulators of ... 12Aubrey BJ, Kelly GL, Janic A, Herold MJ & Strasser A (2018) How does p53 induce apoptosis and how does this relate to p53- ... This finding confirms the notion that p53-BAK and p53-BCL-XL complexes trigger apoptosis [[12, 13, 20]] and we present a ... 2D,E). Irinotecan plus entinostat evoked pan-γH2AX staining in HCT116wt cells, a sign of apoptosis [[41]], and reduced the ...
This included interference with proliferation, differentiation, and apoptosis of NK, T-, and B-cell populations (Ricciardi et ... Granzyme B-activated p53 interacts with Bcl-2 to promote cytotoxic lymphocyte-mediated apoptosis. J Immunol 194, 418-428. ... The EMT-TF SLUG has been found to antagonize p53-mediated apoptosis by repressing PUMA, therefore promoting BCL2 function and ... Snail and slug mediate radioresistance and chemoresistance by antagonizing p53-mediated apoptosis and acquiring a stem-like ...
... apoptosis, autophagy, and changes in metabolism in human subjects with delirium. These tracers include sphingosine-1-phosphate ...
2009) Age-related hearing loss in C57BL/6J mice is mediated by Bak-dependent mitochondrial apoptosis. Proc. Natl. Acad. Sci. ...
Y-27632 dihydrochloride monohydrate is a Rho kinase inhibitor that prevents apoptosis and thereby increases the number of ...
14 S. Ambati, H.K. Kim, J.Y. Yang, J. Lin, M.A. Della-Fera, C.A. Baile, Effects of leptin on apoptosis and adipogenesis in 3T3- ...
Nrf2 activators and itaconate inhibit inflammation at low dose and promote IL-1beta production and inflammatory apoptosis at ...
... such as apoptosis, angiogenesis, cell migration, and invasion (5-7). A recent study from our group implicated Sema3B in the ...