Synergy Testing of FDA-Approved Drugs Identifies Potent Drug Combinations against Trypanosoma cruzi - GOV.UK
Existing antiparasitic drugs for Chagas disease have significant toxicities and suboptimal effectiveness, hence new therapeutic ... An estimated 8 million persons, mainly in Latin America, are infected with Trypanosoma cruzi, the etiologic agent of Chagas ...https://www.gov.uk/dfid-research-outputs/synergy-testing-of-fda-approved-drugs-identifies-potent-drug-combinations-against-trypanosoma-cruzi
Efficacy of imidacloprid + moxidectin and selamectin topical solutions against the KS1 Ctenocephalides felis flea strain...
Antiparasitic Agents / administration & dosage. Cat Diseases / drug therapy*, parasitology. Cats. Ctenocephalides / drug ... 0/Antiparasitic Agents; 0/Imidazoles; 0/Insecticides; 0/Macrolides; 0/Nitro Compounds; 3BN7M937V8/imidacloprid; 51570-36-6/ ...http://www.biomedsearch.com/nih/Efficacy-Imidacloprid-Moxidectin-Selamectin-topical/21914186.html
Halofuginone Hydrobromide in Treating Patients With HIV-Related Kaposi's Sarcoma - Full Text View - ClinicalTrials.gov
Antineoplastic Agents. Coccidiostats. Antiprotozoal Agents. Antiparasitic Agents. Anti-Infective Agents. Protein Synthesis ... Use of investigational agents other than antiretroviral drugs available under expanded access or compassionate use protocols ... patients may receive any FDA approved antiretroviral therapy or agents available through a treatment IND; concurrent treatment ...https://clinicaltrials.gov/show/NCT00064142?order=191
Antifungal Locks to Treat Fungal-related Central Line Infections - Full Text View - ClinicalTrials.gov
Antifungal Agents. Miconazole. Amebicides. Antiprotozoal Agents. Antiparasitic Agents. Anti-Infective Agents. Anti-Bacterial ... Antimicrob Agents Chemother. 2002 Jun;46(6):1773-80. Siegman-Igra Y, Anglim AM, Shapiro DE, Adal KA, Strain BA, Farr BM. ... Antimicrob Agents Chemother. 2004 May;48(5):1727-32. Johnson DC, Johnson FL, Goldman S. Preliminary results treating persistent ... Agents. 14-alpha Demethylase Inhibitors. Cytochrome P-450 Enzyme Inhibitors. Enzyme Inhibitors. Molecular Mechanisms of ...https://clinicaltrials.gov/show/NCT00936910
In Vivo Drug Interaction Pharmacokinetic Study of Tenofovir 1% Gel and Three Commonly Used Vaginal Products - Full Text View -...
Anti-HIV Agents. Reproductive Control Agents. Physiological Effects of Drugs. Antiprotozoal Agents. Antiparasitic Agents. ... Contraceptive Agents. Ethinyl Estradiol. Antiviral Agents. Anti-Infective Agents. Reverse Transcriptase Inhibitors. Nucleic ...https://clinicaltrials.gov/ct2/show/NCT01813162?term=%22microbicide%22+AND+%22gel%22&recr=Open&cond=HIV&rank=12
IH636 Grape Seed Extract in Preventing Breast Cancer in Postmenopausal Women at Risk of Developing Breast Cancer - Full Text...
Protective Agents. Physiological Effects of Drugs. Antiprotozoal Agents. Antiparasitic Agents. Anti-Infective Agents. ... Antineoplastic Agents, Phytogenic. Antineoplastic Agents. Antioxidants. Molecular Mechanisms of Pharmacological Action. ...https://clinicaltrials.gov/ct/gui/show/NCT00100893?order=7
A Pilot Study to Test Activity of Antimalarial Drugs Against an Induced Malaria Infection in Healthy Volunteers - Full Text...
Antiprotozoal Agents. Antiparasitic Agents. Anti-Infective Agents. Enzyme Inhibitors. Molecular Mechanisms of Pharmacological ... study using a BSP inoculum challenge as a model to assess the activity of antimalarial agents. The study will be conducted in 2 ... of a protocol for inducing a falciparum malaria infection in healthy volunteers in order to test the activity of novel agents ...https://clinicaltrials.gov/show/NCT01055002
Caspofungin Based Combined Anti-fungal Therapy for Proven or Probable Invasive Fungal Infection - Full Text View -...
Antiprotozoal Agents. Antiparasitic Agents. Anti-Bacterial Agents. Cytochrome P-450 CYP2C9 Inhibitors. ... Antifungal Agents. Miconazole. Anti-Infective Agents. 14-alpha Demethylase Inhibitors. Cytochrome P-450 Enzyme Inhibitors. ...https://clinicaltrials.gov/ct2/show/NCT01501708
ATAQ EASY: Artesunate + Amodiaquine Fixed Dose Combination in the Treatment of Uncomplicated Plasmodium Falciparum Malaria -...
... antidepressant agents, certain antibiotics including drugs in the macrolide class, fluoroquinolones, imidazole and triazole, ... antifungal agents, certain non-sedative antihistamines (terfenadine, astemizole) and cisapride. *certain known electrolyte ...https://clinicaltrials.gov/ct2/show/NCT00316329
VL-2397 Compared to Standard First-Line Treatment for Invasive Aspergillosis (IA) in Adults - Full Text View - ClinicalTrials...
Antifungal Agents. Anti-Infective Agents. 14-alpha Demethylase Inhibitors. Cytochrome P-450 Enzyme Inhibitors. Enzyme ... Investigational agent VL-2397 600 mg IV infusion administered every day for 28 days (4 weeks) followed by 2 weeks of standard ... Drug: Investigational Agent: VL-2397 Drug: Standard treatment: Voriconazole, Isavuconazole, or Liposomal amphotericin B Phase 2 ... Drug: Investigational Agent: VL-2397 VL-2397. Drug: Standard treatment: Voriconazole, Isavuconazole, or Liposomal amphotericin ...https://clinicaltrials.gov/ct/show/NCT03327727
Study of Trimethoprim/Sulfamethoxazole as PCP Prophylaxis in CTD Patients - Full Text View - ClinicalTrials.gov
Anti-Infective Agents, Urinary. Anti-Infective Agents. Renal Agents. Antimalarials. Antiprotozoal Agents. Antiparasitic Agents ... treated with high-dose glucocorticoids and immunosuppressive agents. ...https://clinicaltrials.gov/ct2/show/NCT01747278?recr=Open&cond=%22Pneumocystis+Infections%22&rank=4
A 28-Day Study of Diclazuril in the Treatment of Cryptosporidiosis in Patients With AIDS - Full Text View - ClinicalTrials.gov
Antidiarrheal agents other than patients on long term loperamide prior to study entry. ...https://clinicaltrials.gov/show/NCT00002278?order=4
A Randomised Trial Investigating the Additional Benefit of Hydroxychloroquine(HCQ)to Short Course Radiotherapy (SCRT) in...
Antiprotozoal Agents. Antiparasitic Agents. Anti-Infective Agents. Enzyme Inhibitors. Molecular Mechanisms of Pharmacological ... Prior radiotherapy, chemotherapy, immunotherapy, biologic agents (e.g., immunotoxins, immunoconjugates, antisense agents, ... Other concurrent chemotherapeutic or investigational agents for this cancer (Concurrent glucocorticoids will be allowed ...https://clinicaltrials.gov/ct2/show/NCT01602588
Amphotericin Alone or in Combination With Fluconazole for AIDS-Associated Meningitis - Full Text View - ClinicalTrials.gov
Antifungal Agents. Anti-Infective Agents. 14-alpha Demethylase Inhibitors. Cytochrome P-450 Enzyme Inhibitors. Enzyme ...https://clinicaltrials.gov/show/NCT00145249?order=53
Moxifloxacin Plus Metronidazole Versus Piperacillin/Tazobactam for the Treatment of Patients With Intra-abdominal Abscesses -...
Contraceptive Agents, Female. Contraceptive Agents. Reproductive Control Agents. Physiological Effects of Drugs. Nucleic Acid ... Anti-Bacterial Agents. Anti-Infective Agents. Topoisomerase II Inhibitors. Topoisomerase Inhibitors. Enzyme Inhibitors. ... Antineoplastic Agents. Contraceptives, Oral, Combined. Contraceptives, Oral. ...https://clinicaltrials.gov/ct2/show/NCT00629135
Study of Positron Emission Tomography and Computed Tomography in Guiding Radiation Therapy in Patients With Stage III Non-small...
Antineoplastic Agents, Phytogenic. Antineoplastic Agents. Tubulin Modulators. Antimitotic Agents. Mitosis Modulators. Molecular ...https://clinicaltrials.gov/ct2/show/NCT01507428?term=cardiac+CT+OR+CAT+scan+OR+coronary+artery+scan&recr=Open&fund=01&rank=19
A Comparison of Dapsone and Trimethoprim-Sulfamethoxazole in the Treatment of Pneumocystis Carinii Pneumonia (PCP) in Patients...
Anti-Infective Agents, Urinary. Anti-Infective Agents. Renal Agents. Antimalarials. Antiprotozoal Agents. Antiparasitic Agents ...https://clinicaltrials.gov/show/NCT00002283?order=13
A Controlled Trial Comparing the Efficacy of Aerosolized Pentamidine and Parenteral / Oral Trimethoprim - Sulfamethoxazole in...
Anti-Infective Agents, Urinary. Anti-Infective Agents. Renal Agents. Antimalarials. Antiprotozoal Agents. Antiparasitic Agents ...https://clinicaltrials.gov/show/NCT00002056?order=40
A Phase II Open Randomized Comparison of 566C80 and Pentamidine Isethionate for the Treatment of Pneumocystis Carinii Pneumonia...
Anti-Infective Agents, Urinary. Anti-Infective Agents. Renal Agents. Antimalarials. Antiprotozoal Agents. Antiparasitic Agents ... Investigational agents including anti-retroviral agents (ddI, ddC, etc.). Patients receiving these drugs prior to entry must ...https://clinicaltrials.gov/show/NCT00001996
Fexinidazole - Wikipedia
Fexinidazole is an antiparasitic agent. It has activity against Trypanosoma cruzi, Tritrichomonas foetus, Trichomonas vaginalis ... Antimicrobial Agents and Chemotherapy. 54 (7): 2893-900. doi:10.1128/AAC.00332-10. PMC 2897277 . PMID 20439607. "Jump-Start on ...https://en.wikipedia.org/wiki/Fexinidazole
Penicillium cluniae - Wikipedia
Penicillium cluniae is a fungus species of the genus of Penicillium which produces the antinematodal and antiparasitic agents ... Liesch, J. M.; Wichmann, C. F. (1990). "Novel antinematodal and antiparasitic agents from Penicillium charlesii. II. Structure ...https://en.wikipedia.org/wiki/Penicillium_cluniae
Avermectin - Wikipedia
Hotson, I. K. (1982). "The avermectins: A new family of antiparasitic agents". Journal of the South African Veterinary ... New Family of Potent Anthelmintic Agents: Producing Organism and Fermentation". Antimicrobial Agents and Chemotherapy. 15 (3): ...https://en.wikipedia.org/wiki/Avermectin
Antiparasitic - Wikipedia
Antiparasitics target the parasitic agents of the infections by destroying them or inhibiting their growth; they are usually ... Between 2000 and 2005, twenty new antiparasitic agents were developed or in development. In 2005, a new antimalarial cost ... Nitazoxanide [NTZ: 2-acetyloxy-N-(5-nitro-2-thiazolyl)benzamide] is a thiazolide antiparasitic agent with excellent activity ... Broad-Spectrum antiparasitics, analogous to broad-spectrum antibiotics for bacteria, are antiparasitic drugs with efficacy in ...https://en.wikipedia.org/wiki/Antiparasitic
Antimicrobial Agents and Chemotherapy - Wikipedia
It covers antimicrobial, antiviral, antifungal, and antiparasitic agents and chemotherapy. The editor-in-chief is Louis B. Rice ... Antimicrobial Agents and Chemotherapy is a peer-reviewed scientific journal published by the American Society for Microbiology ...https://en.wikipedia.org/wiki/Antimicrobial_Agents_and_Chemotherapy
Lipid - Wikipedia
Many commonly used anti-microbial, anti-parasitic, and anti-cancer agents are polyketides or polyketide derivatives, such as ... "Biosynthetic engineering of polyene macrolides towards generation of improved antifungal and antiparasitic agents". Current ...https://en.wikipedia.org/wiki/Lipid
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