Cure of overt diabetes in NOD mice by transient treatment with anti-lymphocyte serum and exendin-4. Diabetes 2004;53:1700-1705 ... Long-term abrogation of autoimmune diabetes in nonobese diabetic mice by immunotherapy with anti-lymphocyte serum. Proc Natl ... anti-lymphocyte serum, in combination with exendin-4, to effectively reverse disease in this animal model of type 1 diabetes ( ... Sera was diluted 1:10,000 and was incubated for 2 h on a plate shaker. The plates were washed five times as before and were ...http://diabetes.diabetesjournals.org/content/58/10/2277
"Secondary disease in irradiated mice grafted with homologous bone marr" by G D. Ledney and D W. Bekkum
Secondary disease in irradiated mice grafted with homologous bone marrow from donors treated with antilymphocyte serum. Abstr. ... "Secondary disease in irradiated mice grafted with homologous bone marrow from donors treated with antilymphocyte serum. Abstr ...https://mouseion.jax.org/ssbb1968/1734/
IMM 0212: Busulfan With Fludarabine and Antithymocyte Globulin as Preparative Therapy for Hematopoietic Stem Cell Transplant...
Antilymphocyte Serum. Vidarabine. Antineoplastic Agents. Antimetabolites, Antineoplastic. Antimetabolites. Molecular Mechanisms ...https://clinicaltrials.gov/show/NCT00228852
Anti-lymphocyte globulin - Wikipedia
Anti-lymphocyte globulin (ALG) is an infusion of animal- antibodies against human T cells which is used in the treatment of ... The product was manufactured by Upjohn and Merieux, as well as the Schweizerisches Serum- und Impfinstitut in Bern, the latter ... "Guillain Barré syndrome precipitated by the use of antilymphocyte globulin in the treatment of severe aplastic anaemia". J. ... Treatment of aplastic anaemia by antilymphocyte glubulin with and without allogeneic bone marrow infusions, in Lancet (1977) 2: ...https://en.wikipedia.org/wiki/Anti-lymphocyte_globulin
The 'immunologic advantage' of HIV-exposed seronegative indi... : AIDS
The induction of anticell immune responses is rather common, and antilymphocyte antibodies have been observed early in sera ... By contrast, serum IgA responses, similar to IgG responses, are dependent on germinal centers and CD28. Thus, they suggested a ... Serum IgA of HIV-exposed uninfected individuals inhibit HIV through recognition of a region within the alpha-helix of gp41. ... Antilymphocyte antibodies in patients with the acquired immune deficiency syndrome. Am J Medicine 1985; 78:621-626.. * Cited ...https://journals.lww.com/aidsonline/fulltext/2009/01140/the__immunologic_advantage__of_hiv_exposed.2.aspx
"NK-2.1: an NK-associated antigen detected with NZB anti-BALB/c serum." by S B Pollack and S L Emmons
Animals, Antilymphocyte Serum, Cell Separation, Complement System Proteins, Fluorescent Antibody Technique, Genetic Linkage, ... Pollack, S B and Emmons, S L, "NK-2.1: an NK-associated antigen detected with NZB anti-BALB/c serum." (1982). Subject Strain ... NK-2.1: an NK-associated antigen detected with NZB anti-BALB/c serum. ...http://mouseion.jax.org/ssbb1982/3743/
"Inactication of thymus and marrow-derived lymphocytes by heterologous " by H Jeejeebhoy
Jeejeebhoy, H, "Inactication of thymus and marrow-derived lymphocytes by heterologous antilymphocyte serum (als)." (1971). ... Inactication of thymus and marrow-derived lymphocytes by heterologous antilymphocyte serum (als). ...https://mouseion.jax.org/ssbb1971/1407/
Induction Therapy Study in Live Donor Kidney Transplant Recipients With a Positive Crossmatch - Full Text View - ClinicalTrials...
Antilymphocyte Serum. Daclizumab. Immunoglobulin G. Anti-Inflammatory Agents. Antiemetics. Autonomic Agents. Peripheral Nervous ... To achieve serum level of 8-10 ng/ml.. Drug: Dexamethasone 100 mg intra-operatively, and 25 mg every 6h post-operatively for ... To achieve serum level of 8-10 ng/ml.. Drug: Dexamethasone 100 mg intra-operatively, and 25 mg every 6h post-operatively for ...https://www.clinicaltrials.gov/ct2/show/NCT00275509
Cord Blood Expansion on Mesenchymal Stem Cells - Full Text View - ClinicalTrials.gov
Antilymphocyte Serum. Rituximab. Fludarabine. Clofarabine. Mycophenolic Acid. Vidarabine. Immunosuppressive Agents. Immunologic ... Serum glutamate pyruvate transaminase (SGPT)/bilirubin , / = to 2.0 x normal (Myeloablative Regimen 4, Reduced Intensity ...https://clinicaltrials.gov/ct2/show/study/NCT00498316?view=results
Fludarabine-Based Conditioning for Allogeneic Marrow Transplantation in Aplastic Anemia - Full Text View - ClinicalTrials.gov
Antilymphocyte Serum. Fludarabine. Vidarabine. Immunosuppressive Agents. Immunologic Factors. Physiological Effects of Drugs. ... serum total bilirubin , 2x upper limit of normal for age as per local laboratory; ALT and AST , 4x upper limit of normal for ... age as per local laboratory; c) renal: serum creatinine , 2x upper limit of normal for age (as per local laboratory). d) ...https://clinicaltrials.gov/ct2/show/NCT00474747?recr=Open&cond=%22Anemia%2C+Aplastic%22&rank=11
Bone Marrow Transplantation in Treating Patients With Hematologic Cancer - Full Text View - ClinicalTrials.gov
DISEASE CHARACTERISTICS: Histologically proven malignancy or condition of the following types: Acute myelogenous leukemia (not M5 or M6) or lymphocytic leukemia in first or greater remission or early relapse OR Chronic myelogenous leukemia OR Myelodysplastic syndrome OR Aggressive or refractory non-Hodgkin's lymphoma OR Aggressive or refractory Hodgkin's disease OR Multiple myeloma at early relapse or after conventional chemotherapy to reduce tumor mass OR High risk chronic lymphocytic leukemia OR Aplastic anemia HLA-matched or 1 antigen mismatched (related or unrelated) available as donor. PATIENT CHARACTERISTICS: Age: 50 and under Performance status: Karnofsky 70-100% Life expectancy: Greater than 8 weeks Hematopoietic: Not specified Hepatic: Bilirubin less than 2 mg/dL SGOT less than 4 times upper limit of normal (ULN) Renal: Creatinine less than 2 times ULN OR Creatinine clearance greater than 60 mL/min Cardiovascular: LVEF at least 50% by MUGA Pulmonary: DLCO at least 50% Other: HIV ...https://clinicaltrials.gov/show/NCT00003398
Dose Escalation Trial of WT1-specific Donor-derived T Cells Following T-Cell Depleted Allogeneic Hematopoietic Stem Cell...
Antilymphocyte Serum. Antineoplastic Agents. Antimetabolites, Antineoplastic. Antimetabolites. Molecular Mechanisms of ... Renal: serum creatinine ,1.2 mg/dl or if serum creatinine is outside the normal range, then CrCl , 40 ml/min (measured or ... Hepatic: , 3x ULN ALT and , 1.5 total serum bilirubin, unless there is congenital benign hyperbilirubinemia. ...https://www.clinicaltrials.gov/ct2/show/NCT01758328
Donor Peripheral Stem Cell or Bone Marrow Transplant in Treating Patients With Relapsed or Refractory Metastatic Kidney Cancer ...
Antilymphocyte Serum. Fludarabine. Mycophenolic Acid. Immunosuppressive Agents. Immunologic Factors. Physiological Effects of ...https://clinicaltrials.gov/show/NCT00262886
Donor Stem Cell Transplant in Treating Patients With Acute Myeloid Leukemia in Remission - Full Text View - ClinicalTrials.gov
Antilymphocyte Serum. Antineoplastic Agents. Antimetabolites, Antineoplastic. Antimetabolites. Molecular Mechanisms of ...https://clinicaltrials.gov/ct2/show/NCT00101140?cond=%22Acute+erythroleukemia%22+%22Acute+erythroid+leukemia%22&rank=6
Ph II of Non-myeloablative Allogeneic Transplantation Using TLI & ATG In Patients w/ Cutaneous T Cell Lymphoma - Full Text View...
Drug Information available for: Cyclosporine Antilymphocyte Serum Genetic and Rare Diseases Information Center resources: ... Antilymphocyte Serum. Enzyme Inhibitors. Molecular Mechanisms of Pharmacological Action. Immunosuppressive Agents. Immunologic ...https://clinicaltrials.gov/show/NCT00896493
Stem Cell Transplantation for Hematological Malignancies - Full Text View - ClinicalTrials.gov
Antilymphocyte Serum. Lenograstim. Immunosuppressive Agents. Immunologic Factors. Physiological Effects of Drugs. Antirheumatic ...https://clinicaltrials.gov/ct2/show/NCT00176839
Hematopoietic Stem Cell Transplantation in High Risk Patients With Fanconi Anemia - Full Text View - ClinicalTrials.gov
Antilymphocyte Serum. Fludarabine. Methylprednisolone Hemisuccinate. Prednisolone. Lenograstim. Vidarabine. Prednisolone ...https://clinicaltrials.gov/ct2/show/NCT00258427?cond=%22Fanconi+anemia%22&rank=5
Treosulfan and Fludarabine Phosphate Before Donor Stem Cell Transplant in Treating Patients With Nonmalignant Inherited...
Antilymphocyte Serum. Busulfan. Vidarabine. Fludarabine. Treosulfan. Abortifacient Agents, Nonsteroidal. Abortifacient Agents. ... Patients with impaired renal function as evidenced by creatinine-clearance , 50% for age, weight, height or serum creatinine , ...https://clinicaltrials.gov/ct2/show/NCT00919503?term=%22Children
High Dose Busulfan and Bortezomib in Treating Patients With High Risk Multiple Myeloma Undergoing Stem Cell Transplant - Full...
Antilymphocyte Serum. Fludarabine. Bortezomib. Vidarabine. Immunosuppressive Agents. Immunologic Factors. Physiological Effects ...https://clinicaltrials.gov/ct2/show/NCT01534143
Allogeneic Stem Cell Transplantation Followed By Targeted Immune Therapy In Average Risk Leukemia - Full Text View -...
Serum creatinine , 1.5 x normal, or. *Creatinine clearance or radioisotope glomerular filtration rate (GFR) 40 ml/min/m2 or , ... Adequate liver function defined as total bilirubin 2.0 x upper limit of normal (ULN), or serum glutamic-oxaloacetic ... transaminase (SGOT)(aspartate aminotransferase (AST)) or serum glutamic-pyruvic transaminase (SGPT)(alanine aminotransferase ( ...https://clinicaltrials.gov/ct2/show/NCT01020539
Thymoglobuline in Non-myeloablative Allogeneic Stem-cell Transplantation - Full Text View - ClinicalTrials.gov
Serum bilirubin , 3 gm/dl; Elevated GPT or GOT , 3 x normal values. ... Antilymphocyte Serum. Immunologic Factors. Physiological Effects of Drugs. Immunosuppressive Agents. To Top ...https://clinicaltrials.gov/ct2/show/NCT00130754
T-cell Depleted Bone Marrow and G-CSF Stimulated Peripheral Stem Cell Transplantation From Related Donors in Treating Patients...
Antilymphocyte Serum. Methylprednisolone Hemisuccinate. Prednisolone. Prednisolone acetate. Methylprednisolone acetate. ...https://www.clinicaltrials.gov/ct2/show/NCT00002718
Visilizumab for the Prevention of Graft-versus-Host Disease After Allogeneic Hematopoietic Cell Transplantation - Full Text...
Antilymphocyte Serum. Abortifacient Agents, Nonsteroidal. Abortifacient Agents. Reproductive Control Agents. Physiological ... serum transaminases must be less than two times the upper limit of normal ...https://clinicaltrials.gov/ct2/show/NCT00720629
Zevalin-Containing Nonmyeloablative Conditioning for Stem Cell Transplantation (SCT) - Full Text View - ClinicalTrials.gov
Antilymphocyte Serum. Vidarabine. Antineoplastic Agents. Immunologic Factors. Physiological Effects of Drugs. Antirheumatic ... Serum creatinine ,/=1.6 mg/dL. Serum bilirubin , 2 mg/dL (unless due to Gilbert's Syndrome). ...https://clinicaltrials.gov/ct2/show/NCT01490723?recr=Open&spons=spectrum+pharmaceuticals&rank=12
Experimental Approaches to Composite Tissue Allograft Transplants | SpringerLink
... tacrolimus and anti-lymphocyte serum substantially reduce the minimum radiation dose for engraftment. Exp Hematol 26(10):927- ... Induction of tolerance to hind limb allografts in rats receiving cyclosporine A and antilymphocyte serum: effect of duration of ... Induction of donor-specific tolerance in rat hind-limb allografts under antilymphocyte serum and cyclosporine A protocol. J ... Use of homozygous allogeneic bone marrow for induction of tolerance with antilymphocyte serum: dose and timing. Transplant Proc ...https://link.springer.com/chapter/10.1007/978-88-470-0374-3_7