*  T follicular helper cells differentiate from Th2 cells in response to helminth antigens | JEM
We find that after helminth infection, or immunization with helminth antigens, reactive lymphoid organs of 4get IL-4/GFP ... we have been studying Th2 response development and regulation in parasitic helminth infections; helminths and antigens derived ... 2 B) and ICOS (not depicted). Thus, in mice mounting a Th2 response to helminth antigens, the great majority of CD4+ T cells ... T follicular helper cells differentiate from Th2 cells in response to helminth antigens. Arielle Glatman Zaretsky, Justin J. ...
  http://jem.rupress.org/content/206/5/991
*  Search of: 'Helminthiasis' - List Results - ClinicalTrials.gov
Antibody isotype response to helminth antigens.. 2377. All. 5 Years to 18 Years (Child, Adult). NCT01658774. 2242. 241642. ... Community Directed Treatment of Soil-Transmitted Helminths Among Young Children in Zambia. *Soil-Transmitted Helminth Infection ... Prevalence of soil-transmitted helminths (Ascaris, hookworm, Trichuris). *Intensity of soil-transmitted helminth infections ( ... Treatment of Helminth co-Infection: Short-Term Effects on HIV-1 Progression Markers and Immune Activation. *HIV Infections ...
  https://clinicaltrials.gov/ct2/results?cond=%22Helminthiasis%22
*  Amy S. McKee, PhD | Department of Medicine | University of Colorado Denver
Helminth antigens modulate TLR-initiated dendritic cell activation. J Immunol. 2004; 173:7454-61. ... Antigen-Specific Regulation of IgE Antibodies by Non-Antigen-Specific gamma-delta T Cells. J Immunol. 2013; 190: 913-21. ... MacLeod M, McKee AS, Crawford F, White J, Kappler J, Marrack P. CD4 memory T cells divide poorly in response to antigen because ... Pearce EJ, M Kane C, Sun J, J Taylor J, McKee AS, Cervi L. Th2 response polarization during infection with the helminth ...
  http://www.ucdenver.edu/academics/colleges/medicalschool/departments/medicine/ClinicalImmunology/Faculty/Pages/AmySMcKee,PhD.aspx
*  Methods, devices, kits and compositions for detecting roundworm, whipworm, and hookworm - IDEXX Laboratories, Inc.
Each specific helminth antibody may be an immobilized antigen capture reagent in a reaction zone (solid phase). A second ... "Antigen capture reagent" refers to any compound that is specific for the antigen or antigens of interest. The labeled antigen ... whipworm antigen, and/or hookworm antigen, wherein the one or more types of roundworm antigen, whipworm antigen, and hookworm ... whipworm antigens and/or hookworm antigens, only to detect one or more roundworm antigens, whipworm antigens and/or hookworm ...
  http://www.freepatentsonline.com/9040245.html
*  Alternaria-induced allergic inflammation to Ovalbumin ( | Open-i
Antigens, Helminth/pharmacology/therapeutic use. *Asthma/drug therapy. *Cells, Cultured. *Disease Models, Animal ... Helminth parasites such as the nematode Heligmosomoides polygyrus strongly inhibit T helper type 2 (Th2) allergy, as well as ... Helminth parasites such as the nematode Heligmosomoides polygyrus strongly inhibit T helper type 2 (Th2) allergy, as well as ... Thus, this helminth parasite targets IL-33 production as part of its armory of suppressive effects, forestalling the ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC4016792_emss-56142-f0001&req=4
*  Patent US7993861 - Methods, devices, kits and compositions for detecting whipworm - Google Patents
Method for the commercial production of helminths antigens. US4789631. Feb 17, 1984. Dec 6, 1988. Synbiotics Corporation. ... "Antigen capture reagent" refers to any compound that is specific for the antigen or antigens of interest. The labeled antigen ... Following binding of the antigen from the sample, the antigen capture reagent/antigen complex is detected by any suitable ... one or more antigen capture reagents (e.g., a non-immobilized labeled antigen capture reagent and an immobilized antigen ...
  http://www.google.com/patents/US7993861?dq=5,666,293
*  Frontiers | Negative Regulation of Humoral Immunity Due to Interplay between the SLAMF1, SLAMF5, and SLAMF6 Receptors |...
... mice also mounted significantly higher antibody responses to T-independent type 2 antigen. Furthermore, treatment of mice with ... mice also mounted significantly higher antibody responses to T-independent type 2 antigen. Furthermore, treatment of mice with ... T follicular helper cells differentiate from Th2 cells in response to helminth antigens. J Exp Med (2009) 206:991-9. doi: ... The fact that enhanced TI-antigen response is only limited to TI-2 antigens suggests that Slamf[1 + 5 + 6]−/− MZ B cell ...
  https://www.frontiersin.org/articles/10.3389/fimmu.2015.00158/full
*  Expected qualitative UCAA2000 test results for samples | Open-i
Antigens, Helminth/urine*. *Glycoproteins/urine*. *Helminth Proteins/urine*. *Schistosoma mansoni/metabolism*. *Schistosomiasis ... based test demonstrating ongoing infections through detection of worm circulating anodic antigen (CAA), was improved for ... based test demonstrating ongoing infections through detection of worm circulating anodic antigen (CAA), was improved for ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC4418045_13071_2015_857_Fig4_HTML&req=4
*  T Lymphocytes: Plasticity of Subsets
2009) T follicular helper cells differentiate from Th2 cells in response to helminth antigens. Journal of Experimental Medicine ... Marrack P and Kappler JW (1976) Antigen‐specific and nonspecific mediatiors of T cell/B cell cooperation. II. Two helper T ... Cantor H and Boyse EA (1975) Functional subclasses of T‐lymphocytes bearing different Ly antigens. I. The generation of ... 2012) Rapid in vivo conversion of effector T cells into Th2 cells during helminth infection. Journal of Immunology 188 (2): 615 ...
  http://www.els.net/WileyCDA/ElsArticle/refId-a0026253.html
*  McKay D[au] - PubMed - NCBI
Helminth Antigen-Conditioned Dendritic Cells Generate Anti-Inflammatory CD4 T Cells Independent of Antigen Presentation via MHC ... mice expel the tapeworm Hymenolepis diminuta and are protected from colitis by triggering a memory response with worm antigen. ...
  https://www.ncbi.nlm.nih.gov/pubmed?cmd=search&term=McKay+D%5Bau%5D&dispmax=50
*  Antibody - Wikipedia
Antibody-antigen interactions[edit]. The antibody's paratope interacts with the antigen's epitope. An antigen usually contains ... helminths, allergens). ... Rh factor, also known as Rh D antigen, is an antigen found on ... Functions mainly as an antigen receptor on B cells that have not been exposed to antigens.[16] It has been shown to activate ... Each of these variants can bind to a different antigen.[2] This enormous diversity of antibody paratopes on the antigen-binding ...
  https://en.wikipedia.org/wiki/Antibody
*  Frontiers | Chemokines in Innate and Adaptive Granuloma Formation | Immunology
During adaptive granuloma formation, polarization of the mycobacterial and helminth antigen bead-elicited chemokine profiles ... B) Histologic appearance and sizes of adaptive antigen bead granulomas. Antigen beads were administered as above, but mice were ... from Mycobacterium bovis and soluble egg antigens (SEA) derived from ova of the helminth parasite Schistosoma mansoni. Detailed ... Size of a non-antigen coated control bead reaction is shown in chart for comparison. Bars are means and standard deviations of ...
  https://www.frontiersin.org/articles/10.3389/fimmu.2013.00043/full
*  Immunoregulation by Taenia crassiceps and Its Antigens
... it is clear that host immune responses to helminth parasitic diseases or to bystander antigens are modulated by helminth- ... Moreover, in vivo assays have also demonstrated that carbohydrates in helminth-derived antigens are essential to bias Th2-type ... We have studied the immune response elicited by this helminth and its antigens in mice and human cells, and have discovered ... It is important to keep in mind that the chemical composition of helminth antigens varies greatly among species, but the most ...
  https://www.hindawi.com/journals/bmri/2013/498583/
*  Characterisation of IgG(T) serum antibody responses to two larval antigen complexes in horses naturally- or experimentally...
Animals, Antibodies, Helminth, Antigens, Helminth, Biomarkers, Horse Diseases, Horses, Immunoglobulin E, Larva, Nematode ... Here, serum IgG(T) responses to two larval antigen complexes of 25 and 20 kDa were quantified in horses with experimental ... Characterisation of IgG(T) serum antibody responses to two larval antigen complexes in horses naturally- or experimentally- ... In naturally exposed horses whose parasite burdens were quantified upon post-mortem examination, antigen-specific IgG(T) ...
  http://epubs.surrey.ac.uk/826685/
*  Tropical eosinophilia - Wikipedia
High antifilarial IgG titers to microfilariae often result in cross reactivity with other nonfilarial helminth antigens, such ... Muck, A.; Pires, M.; Lammie, P. (2003). "Influence of infection with non-filarial helminths on the specificity of serological ... as strongyloides and schistosoma antigens, as demonstrated in reported cases. It is important to exclude other parasitic ...
  https://en.wikipedia.org/wiki/Tropical_eosinophilia
*  Inflammatory bowel disease and the hygiene hypothesis: an argument for the role of helminths | Springer for Research &...
Antigen-specific cellular hyporesponsiveness in a chronic human helminth infection is mediated by T(h)3/T(r)1-type cytokines IL ... Modulation of murine cytokine responses to mycobacterial antigens by helminth-induced T helper 2 cell responses. J Immunol 1993 ... Effect of deworming on human T cell responses to mycobacterial antigens in helminth-exposed individuals before and after ... We will consider the effective eradication of helminths during this time period and the effects of helminths on immunity. We ...
  https://rd.springer.com/chapter/10.1007/978-3-7643-8903-1_9
*  Filarial lymphedema is associated with increased expres | Open-i
Antigens, Helminth/immunology*. *Filariasis/immunology*/pathology*. *Inflammation/immunology/pathology*. *Lymphedema/immunology ... Filarial lymphedema is characterized by antigen-specific Th1 and th17 proinflammatory responses and a lack of regulatory T ... Filarial lymphedema is characterized by antigen-specific Th1 and th17 proinflammatory responses and a lack of regulatory T ... we examined specific sets of cytokines in individuals with filarial lymphedema in response to parasite antigen (BmA) and ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC2666805_pntd.0000420.g005&req=4
*  Follicular B helper T cells - Wikipedia
May 2009). "T follicular helper cells differentiate from Th2 cells in response to helminth antigens". J Exp Med. 206 (5): 991-9 ... In germinal centers, antigen-experienced TFH cells rapidly upregulate the expression of CD40L, which binds and stimulates the B ... Follicular B helper T cells (also known as just follicular helper T cells or TFH), are antigen-experienced CD4+ T cells found ... Therefore, in the absence of TFH cells, similar to B cell activation by T-cell independent antigens, a quick burst of low ...
  https://en.wikipedia.org/wiki/Follicular_B_helper_T_cells
*  Trichinella spiralis paramyosin activates mouse bone marrow-derived dendritic cells and induces regulatory T cells | Parasites ...
... are antigen-presenting cells that regulate T cell responses for many infectious diseases. The tissue-dwelling nematode ... Our results are consistent with other studies that showed parasitic helminth antigens activated DCs to incomplete maturation [ ... the specific mechanism during interaction between DC and helminthic antigens, especially in the role of helminth immune evasion ... All antigens were stored at -80 °C.. Generation of dendritic cells. DCs were generated from mouse bone marrow cells as ...
  https://parasitesandvectors.biomedcentral.com/articles/10.1186/s13071-016-1857-y
*  Blood and Lymph Unit 3 Flashcards by Kristen Stahl | Brainscape
worms shed antigen that diffuse to mast cells. -Mast cells' FceR are loaded then with anti-helminth IgE. -antigen cross links ... Cross reaction of foreign antigen with self: foreign+self antigen. would be good if we could identify antigens that start rxn. ... Often by the time symptoms show up, triggering antigen is long gone. Coupling Self antigen with Foreign Antigen "carrier": have ... which is toxic to helminths. Second partner is Th2:. -Th2 goes out into body like a Th1 cell, finds helminth antigens on an APC ...
  https://www.brainscape.com/flashcards/blood-and-lymph-unit-3-4806757/packs/6999439
*  Alternaria induces a rapid innate eosinophilia and ILC2 | Open-i
Antigens, Helminth/pharmacology/therapeutic use. *Asthma/drug therapy. *Cells, Cultured. *Disease Models, Animal ... Helminth parasites such as the nematode Heligmosomoides polygyrus strongly inhibit T helper type 2 (Th2) allergy, as well as ... Helminth parasites such as the nematode Heligmosomoides polygyrus strongly inhibit T helper type 2 (Th2) allergy, as well as ... Thus, this helminth parasite targets IL-33 production as part of its armory of suppressive effects, forestalling the ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC4016792_emss-56142-f0004&req=4
*  Blocking ELISA for epitope analysis of the anti-T. colu | Open-i
Antigens, Helminth/genetics/immunology*/metabolism. *Carbohydrates/genetics/immunology*. *Epitopes/genetics/immunology*. * ... The carbohydrate larval antigen, CarLA, is present on the exposed surface of all strongylid nematode infective L3 larvae tested ... The carbohydrate larval antigen, CarLA, is present on the exposed surface of all strongylid nematode infective L3 larvae tested ... As expected, Tc.2 phage binding, which binds to a sheath antigen that is also present in the extracts, was not inhibited by any ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC2742895_ppat.1000597.g002&req=4
*  Tapeworms as a cause of intestinal disease in horses. - Surrey Research Insight Open Access
Animals, Antibodies, Helminth, Antigens, Helminth, Blotting, Western, Cestoda, Cestode Infections, Colic, Enzyme-Linked ...
  http://epubs.surrey.ac.uk/826703/
*  The American Journal of Tropical Medicine and Hygiene | Tuberculin Skin-Test Reactions Are Unaffected by the Severity of...
Helminths suppress cell-mediated immunity, so we studied the effect of helminth infection and deworming on the TST in a ... helminths were reduced, but 63% remained infected with helminths. Albendazole did not cause a change in TST size (P = 0.8) or ... and TST interpretation was unaffected by high-burden helminth infections and co-infection with multiple helminth species. ... Thus, TST reactions were unaffected by albendazole therapy that partially cured intestinal helminth infections, ...
  http://www.ajtmh.org/content/journals/10.4269/ajtmh.2010.10-0073
*  25 year old female presents with persistent flu-like symptoms
1. Helminths Overview. *2. Type 2 Immunity to Helminths. *3. Helminths Exploiting Immune Regulation ... 4. MHC & Antigen Presentation. *5. Overview of T Cell Subsets. *6. Antibody Generation by B cells ...
  https://www.immunopaedia.org.za/clinical-cases/drug-response/25-year-old-female-presents-with-persistent-flu-like-symptoms/