*  Antifibrinolytics Found to Reduce Bleeding Safely in Elective Surgery | Medpage Today
Three antifibrinolytic agents each reduced blood loss and red-cell transfusions associated with elective surgery, without an ... 17 -- Three antifibrinolytic agents each reduced blood loss and red-cell transfusions associated with elective surgery, without ... Antifibrinolytic drugs are widely used, particularly in cardiac surgery, and previous reviews have found them effective in ... The principal need is for larger comparative trials to assess the relative efficacy, safety, and cost-effectiveness of anti-fibrinolytic ...
  https://www.medpagetoday.com/surgery/generalsurgery/7012
*  Clinical Randomisation of an Antifibrinolytic in Significant Haemorrhage - Full Text View - ClinicalTrials.gov
Antifibrinolytic Agents. Fibrin Modulating Agents. Molecular Mechanisms of Pharmacological Action. Hemostatics. Coagulants. ... Coats T, Hunt B, Roberts I, Shakur H. Antifibrinolytic agents in traumatic haemorrhage. PLoS Med. 2005 Mar;2(3):e64. Epub 2005 ... as to whether or not to use an antifibrinolytic agent in a particular adult with traumatic haemorrhage. Patients for whom the ... eligible if the responsible doctor is for any reason substantially uncertain whether or not to use an antifibrinolytic agent. ...
  https://clinicaltrials.gov/show/NCT00375258
*  Mephyton (TN) - Antifibrinolytic Agents, Vitamins (Vitamin K)
Phytonadione is a vitamin, indicated in the treatment of coagulation disorders which are due to faulty formation of factors II, VII, IX and X when caused by vitamin K deficiency or interference with vitamin K activity. Phytonadione aqueous colloidal solution of vitamin K1 for parenteral injection, possesses the same type and degree of activity as does naturally-occurring vitamin K, which is necessary for the production via the liver of active prothrombin (factor II), proconvertin (factor VII), plasma thromboplastin component (factor IX), and Stuart factor (factor X ...
  http://pharmacycode.com/Mephyton_%28TN%29.html
*  Tioconazolum [INN-Latin] - Antifibrinolytic Agents, ATC:B02AA02
Tranexamic acid is an antifibrinolytic that competitively inhibits the activation of plasminogen to plasmin. Tranexamic acid is ...
  http://pharmacycode.com/Tioconazolum_%5BINN-Latin%5D.html
*  Apitherapy News: Bee Venom Peptide is Anti-Fibrinolytic, Anti-Microbial Agent
Bee Venom Peptide is Anti-Fibrinolytic, Anti-Microbial Agent Secapin, a bee venom peptide, exhibits anti-fibrinolytic, anti- ... venom peptide secapin has multifunctional roles as an anti-fibrinolytic agent during fibrinolysis and an anti-microbial agent ... thus indicating the role of AcSecapin-1 as an anti-fibrinolytic agent. AcSecapin-1 also inhibited both human neutrophil and ... Here, we provide the evidence that Asiatic honeybee (Apis cerana) secapin (AcSecapin-1) exhibits anti-fibrinolytic, anti- ...
  http://apitherapy.blogspot.com/2016/05/bee-venom-peptide-is-anti-fibrinolytic.html
*  An Open-label, Randomized, Multicenter Phase IIIb Study to Assess the Efficacy, Safety and Tolerance of BERIPLEX┬« P/N (Kcentra)...
Antifibrinolytic Agents. Fibrin Modulating Agents. Molecular Mechanisms of Pharmacological Action. Hemostatics. Coagulants. ... Reversal of VKA therapy alone may not resolve the coagulopathy (eg, receiving a potent anti-platelet agent, i.e., clopidogrel ...
  https://clinicaltrials.gov/ct2/show/NCT00803101?term=Blood+Coagulation+Disorders%3A+Clinical+Trials&rank=11
*  Hemostatic and Anti-Inflammatory Effects of Ulinastatin and Tranexamic Acid in Cardiopulmonary Bypass Cardiac Surgery - Full...
Anti-Inflammatory Agents. Urinastatin. Antifibrinolytic Agents. Fibrin Modulating Agents. Molecular Mechanisms of ... The extensively studied antifibrinolytic drug aprotinin is efficacious but expensive, and has been proved to link to higher ... An effective and secure hemostatic agent is badly needed. Ulinastatin, urinary trypsin inhibitor(UTI), is a secreted Kunitz- ... Limited studies offered clues to its antifibrinolytic effect. Tranexamic acid has been applied for years with convinced ...
  https://clinicaltrials.gov/ct2/show/NCT01060189
*  Tinzaparin in the Treatment of the Acute Pulmonary Embolism - Full Text View - ClinicalTrials.gov
Antifibrinolytic Agents. Fibrin Modulating Agents. Molecular Mechanisms of Pharmacological Action. Hemostatics. Coagulants. ...
  https://clinicaltrials.gov/ct2/show/NCT00711308
*  Study Of Tranexamic Acid For The Reduction Of Blood Loss In Patients Undergoing Major Abdominal Surgery - Full Text View -...
Antifibrinolytic Agents. Fibrin Modulating Agents. Molecular Mechanisms of Pharmacological Action. Hemostatics. Coagulants. ...
  https://clinicaltrials.gov/ct2/show/NCT00827931
*  Tranexamic Acid for Upper Gastrointestinal Bleeding - Full Text View - ClinicalTrials.gov
Antifibrinolytic Agents. Fibrin Modulating Agents. Molecular Mechanisms of Pharmacological Action. Hemostatics. Coagulants. ...
  https://clinicaltrials.gov/ct2/show/NCT01713101
*  Blood Loss and Transfusion Requirement in Infants Treated With Tranexamic Acid - Full Text View - ClinicalTrials.gov
Antifibrinolytic Agents. Fibrin Modulating Agents. Molecular Mechanisms of Pharmacological Action. Hemostatics. Coagulants. ... Current antifibrinolytic therapy as these patients may bleed less. *Patient or family history of thromboembolic disease as ... Tranexamic acid (TXA) is a synthetic antifibrinolytic drug that competitively inhibits the lysine binding sites of plasminogen ...
  https://clinicaltrials.gov/ct2/show/NCT01094977?cond=%22craniosynostoses%22+OR+%22muenke+syndrome%22&rank=5
*  Long-term Treatment for Cancer Patients With Deep Venous Thrombosis or Pulmonary Embolism - Full Text View - ClinicalTrials.gov
Fibrinolytic Agents. Fibrin Modulating Agents. Molecular Mechanisms of Pharmacological Action. Antifibrinolytic Agents. ...
  https://clinicaltrials.gov/ct2/show/NCT01164046
*  Safety Study of XP12B in Women With Menorrhagia - Full Text View - ClinicalTrials.gov
Antifibrinolytic Agents. Fibrin Modulating Agents. Molecular Mechanisms of Pharmacological Action. Hemostatics. Coagulants. ... event is an event that may be explained by administration of the study drug or by the subjects's clinical state or other agents ... event most likely to be explained by administration of the study drug rather than the subjects's clinical state or other agents ...
  https://clinicaltrials.gov/ct2/show/NCT00113568?term=Menstruation+Disturbances%3A+Clinical+Trials&rank=19
*  Tranexamic Acid Versus Placebo for the Reduction of Blood Loss in Total Hip Replacement Surgery - Full Text View -...
Antifibrinolytic Agents. Fibrin Modulating Agents. Molecular Mechanisms of Pharmacological Action. Hemostatics. Coagulants. ...
  https://clinicaltrials.gov/ct2/show/NCT01199627
*  Tranexamic Acid for Craniofacial Surgery - Full Text View - ClinicalTrials.gov
Antifibrinolytic Agents. Fibrin Modulating Agents. Molecular Mechanisms of Pharmacological Action. Hemostatics. Coagulants. ... Henry DA, Moxey AJ, Carless PA, O'Connell D, McClelland B, Henderson KM, Sly K, Laupacis A, Fergusson D. Anti-fibrinolytic use ...
  https://clinicaltrials.gov/ct2/show/NCT00722436?term=Craniosynostosis&rank=9
*  Reversal Agent Use in Patients Treated With Direct Oral Anticoagulants or Vitamin K Antagonists - Full Text View -...
Antifibrinolytic Agents. Fibrin Modulating Agents. Molecular Mechanisms of Pharmacological Action. Hemostatics. Coagulants. ... Reversal Agent Use in Patients Treated With Direct Oral Anticoagulants or Vitamin K Antagonists (RADOA). This study is ... reversal agents [e.g. vitamin K, prothrombin complex concentrate (PCC), activated PCC (aPCC), activated factor VII (aVII), ... The Registry will offer the opportunity to evaluate the effects of reversal agents as PCC, aPCC, rVIIa, specific antidots in e. ...
  https://clinicaltrials.gov/ct2/show/NCT01722786?recr=Open&cond=%22Anticoagulants%22&rank=13
*  Most recent papers with the keyword preoperative EPO | Read by QxMD
BACKGROUND: Erythropoiesis-stimulating agents, such as erythropoietin (EPO), can be used to treat preoperative anemia. Some ... and antifibrinolytic therapy (AFT). The goal of this study was to investigate additional preventive factors involved in the ... antifibrinolytics, and the use of a tourniquet... ...
  https://www.readbyqxmd.com/keyword/109433