*  Recent Articles | Broadly Cross-neutralizing Antibodies And Immunology | The Scientist Magazine®| Page 4
tags: broadly cross-neutralizing antibodies x immunology x The Scientist. » broadly cross-neutralizing antibodies and ... A family of broadly neutralizing antibodies from a chronically infected donor provides a schematic for designing vaccines and ... Unique Antibodies Open Path Toward New HIV Vaccines. By Amanda B. Keener , January 27, 2017 ... Anti-Flavivirus Antibodies Enhance Zika Infection in Mice. By Anna Azvolinsky , March 30, 2017 ...
  https://www.the-scientist.com/?articles.list/tagNo/2744,12/tags/broadly-cross-neutralizing-antibodies,immunology/pageNo/4/
*  RCSB PDB - 4LSS: Crystal structure of broadly and potently neutralizing antibody VRC01 in complex with HIV-1 clade A strain KER...
Crystal structure of broadly and potently neutralizing antibody VRC01 in complex with HIV-1 clade A strain KER_2018_11 gp120 ...
  https://www.rcsb.org/structure/4lss
*  Recent Articles | Broadly Cross-neutralizing Antibodies | The Scientist Magazine®
A family of broadly neutralizing antibodies from a chronically infected donor provides a schematic for designing vaccines and ... Unique Antibodies Open Path Toward New HIV Vaccines. By Amanda B. Keener , January 27, 2017 ... track the evolution of HIV in a single patient to understand what drives the production of broadly neutralizing antibodies. ... A synthetic antibody prevents infection in four monkeys injected with heavy doses of the virus. ...
  https://www.the-scientist.com/?articles.list/tagNo/2744/tags/broadly-cross-neutralizing-antibodies/
*  IMMUNOGEN DESIGN TO INDUCE HIV NEUTRALIZING ANTIBODIES | CROI Conference
Induction of broadly neutralizing antibodies (bnAbs) is a major HIV vaccine goal. We hypothesize that consistent bnAb ... to shepherd antibody maturation toward bnAb development. To test this hypothesis, we have focused our initial immunogen design ...
  http://www.croiconference.org/sessions/immunogen-design-induce-hiv-neutralizing-antibodies
*  Cell Based Neutralizing Antibody Assays
... Cell-based anti-drug neutralizing antibody (NAb) assays for safety and efficacy ... Experienced cell-based neutralizing antibody assay capabilities. Our experts, based in Good Laboratory Practice (GLP) compliant ... Cell-based neutralizing antibody assays can be difficult to develop as the selection of the most suitable assay type (indirect ... Cell-based assays mimic the mechanism by which the neutralizing antibodies (NAbs) exert their effect in vivo and are the ...
  http://www.intertek.com/pharmaceutical/immunochemistry/cell-based-assays/
*  Broadly neutralizing antibodies to prevent HIV-1 | Science
These are referred to as broadly neutralizing antibodies (bnAbs). Such antibodies can be detected in about 25% of persons with ... Studies show the potential of synthetic and combinations of broadly neutralizing antibodies ... Studies show the potential of synthetic and combinations of broadly neutralizing antibodies ... Advances in technology-especially single-cell antibody cloning techniques-have led to the isolation and characterization of ...
  http://science.sciencemag.org/content/358/6359/46.summary
*  Broadly Neutralizing Antibodies in HIV Patients | The Scientist Magazine®
... and the infection itself that influence whether a person with HIV will produce broadly neutralizing antibodies. ... broadly neutralizing antibodies. disease/medicine. HIV. HIV vaccine. infectious disease. vaccination. vaccine. ... Broadly Neutralizing Antibodies in HIV Patients. Researchers identify aspects of the patient, the virus, and the infection ... WIKIMEDIA, BRUCEBLAUSEOnly about 1 percent of HIV-infected people will generate the broadly neutralizing antibodies that target ...
  https://www.the-scientist.com/the-nutshell/broadly-neutralizing-antibodies-in-hiv-patients-32797
*  Recent Articles | Broadly Cross-neutralizing Antibodies | The Scientist Magazine®
A family of broadly neutralizing antibodies from a chronically infected donor provides a schematic for designing vaccines and ... Unique Antibodies Open Path Toward New HIV Vaccines. By Amanda B. Keener , January 27, 2017 ... track the evolution of HIV in a single patient to understand what drives the production of broadly neutralizing antibodies. ... A synthetic antibody prevents infection in four monkeys injected with heavy doses of the virus. ...
  https://www.the-scientist.com/?articles.list/categoryNo/2625/category/The-Scientist/tagNo/2744/tags/broadly-cross-neutralizing-antibodies/
*  JCI - Towards HIV-1 remission: potential roles for broadly neutralizing antibodies
Recently discovered broadly neutralizing antibodies (bNAbs) exhibit remarkable breadth and potency in their ability to ... bNAbs can prevent infection by directly neutralizing cell-free virions, which prevents infection and accelerates viremia ... decline through antibody-mediated viral clearance. (. B. ) bNAbs can potentially bind to infected cells and mediate antiviral ...
  https://www.jci.org/articles/view/80561/figure/1
*  Viruses | Free Full-Text | Recombinant Sheep Pox Virus Proteins Elicit Neutralizing Antibodies
Virus-neutralizing activity against SPPV in lamb kidney cell culture was detected for polyclonal antisera raised to SPPV-060, ... To our knowledge, this is the first report demonstrating the virus-neutralizing activities of antisera raised to SPPV-060, SPPV ... The aim of this work was to evaluate the immunogenicity and neutralizing activity of sheep pox virus (SPPV; genus Capripoxvirus ... Recombinant Sheep Pox Virus Proteins Elicit Neutralizing Antibodies. Olga V. Chervyakova 1. ...
  http://www.mdpi.com/1999-4915/8/6/159
*  Powerful HIV-Neutralizing Antibody s Pictures Revealed By Scripps Researchers
Researchers at The Scripps Research Institute have uncovered the surprising details of how a powerful anti-HIV antibody grabs ... in smaller concentrations of antibody molecules than any previously reported broadly neutralizing anti-HIV antibody. The new ... Powerful HIV-Neutralizing Antibody s Pictures Revealed By Scripps Researchers. by Tanya Thomas on October 16, 2011 at 3:12 PM ... Since the 1990s, Burton, Wilson, and other researchers have been searching for such "broadly neutralizing" antibodies against ...
  http://www.medindia.net/news/Powerful-HIV-Neutralizing-Antibodys-Pictures-Revealed-By-Scripps-Researchers-92031-1.htm
*  Frontier Biotech licenses 3BNC117, a novel broad-spectrum HIV neutralizing antibody
... Tuesday, July 25, 2017 AIDS/HIV News ... 3BNC117, a novel broad-spectrum HIV neutralizing antibody, with albuvirtide for the treatment and prophylaxis of HIV infection ... 3BNC117 is one of the most effective broad-spectrum HIV neutralizing antibodies. Several phase 1 and phase 2 clinical trials ... www.prnewswire.com/news-releases/frontier-biotech-licenses-3bnc117-a-novel-broad-spectrum-hiv-neutralizing-antibody-300493440. ...
  http://www.medindia.net/health-press-release/Frontier-Biotech-licenses-3BNC117-a-novel-broad-spectrum-HIV-neutralizing-antibody-335092-1.htm
*  Abstract 1602: Generation of anti-IL-17B antibodies neutralizing IL-17B-mediated alterations of the immune microenvironment,...
Generation of anti-IL-17B antibodies neutralizing IL-17B-mediated alterations of the immune microenvironment, promotion of ... Abstract 1602: Generation of anti-IL-17B antibodies neutralizing IL-17B-mediated alterations of the immune microenvironment, ... Abstract 1602: Generation of anti-IL-17B antibodies neutralizing IL-17B-mediated alterations of the immune microenvironment, ... Abstract 1602: Generation of anti-IL-17B antibodies neutralizing IL-17B-mediated alterations of the immune microenvironment, ...
  http://cancerres.aacrjournals.org/content/77/13_Supplement/1602
*  Recent Articles | Broadly Cross-neutralizing Antibodies And Genetics & Genomics | The Scientist Magazine®
tags: broadly cross-neutralizing antibodies x genetics & genomics x The Scientist. » broadly cross-neutralizing antibodies and ... Researchers Produce Alpaca Antibodies Using Yeast. By Catherine Offord , February 14, 2018 ... With multiple applications in biomedicine, the antibodies can now be made quickly, cheaply, and without the need for an alpaca ... Researchers identify antibodies for two commonly used Cas9 proteins in human blood. Investors take notice. ...
  https://www.the-scientist.com/?articles.list/categoryNo/2625/category/The-Scientist/tagNo/2744,9/tags/broadly-cross-neutralizing-antibodies,genetics--amp--genomics/
*  Biosimilar recombinant human erythropoietin induces the production of neutralizing antibodies
Sera from 23 of these patients were positive for r-HuEpo-neutralizing antibodies, and their bone marrow biopsies indicated pure ... Pure red cell aplasia (PRCA) due to neutralizing antibodies can rarely develop following treatment with epoetin. The treatment ... Sera and bone marrow biopsies from the remaining seven patients were negative for anti-r-HuEpo antibodies and red-cell aplasia ...
  http://connection.ebscohost.com/c/articles/61249144/biosimilar-recombinant-human-erythropoietin-induces-production-neutralizing-antibodies
*  Eliciting HIV-Neutralizing Antibodies Possible With New Route Developed By NIH-Led Team
Researchers have traced in detail how certain powerful HIV neutralizing antibodies evolve, a finding that generates vital clues ... The genes that coded for HIV neutralizing antibodies grouped together on the same branches of the trees. Next, the researchers ... Eliciting HIV-Neutralizing Antibodies Possible With New Route Developed By NIH-Led Team. ... Researchers have traced in detail how certain powerful HIV neutralizing antibodies evolve, a finding that generates vital clues ...
  http://www.medindia.net/news/Eliciting-HIV-Neutralizing-Antibodies-Possible-With-New-Route-Developed-By-NIH-Led-Team-89140-1.htm
*  Viruses | Free Full-Text | Neutralizing Antibodies and Pathogenesis of Hepatitis C Virus Infection | HTML
Furthermore, viral evasion from host neutralizing antibodies has been revealed to be an important contributor in leading both ... This review summarizes recent concepts of the role of neutralizing antibodies in viral clearance and protection, and highlights ... There is increasing evidence that host neutralizing responses play a relevant role in the resulting pathogenesis. ... consequences of viral escape from neutralizing antibodies in the pathogenesis of HCV infection. ...
  http://www.mdpi.com/1999-4915/4/10/2016/htm
*  TSRI Scientists Get First-Ever Glimpse of 'Teenage' HIV-Neutralizing Antibody | Scripps Research
... the antibody found in this donor resembled members of the VRC01 class of antibodies, which are "broadly neutralizing antibodies ... The researchers managed to tweak the immature antibody to make it into a broadly neutralizing antibody. "As long as you have ... Yet the new antibody also lacked one of the key structural traits of VRC01 antibodies. "There was something a little bit weird ... Further studies into the antibody's genetics and structure showed that it was a precursor to mature VRC01 antibodies-in other ...
  https://www.scripps.edu/news-and-events/press-room/2016/20160405zhu.html
*  Inhibition of TGF-beta with neutralizing antibodies prevents radiation-induced acceleration of metastatic cancer progression. ...
Inhibition of TGF-β with neutralizing antibodies prevents radiation-induced acceleration of metastatic cancer progression. [J ... These effects were abrogated by administration of a neutralizing pan-TGF-beta antibody. Circulating polyomavirus middle T ... TGF-β-neutralizing antibody 2G7 blocks radiation-induced increase in lung metastases. ... Inhibition of TGF-beta with neutralizing antibodies prevents radiation-induced acceleration of metastatic cancer progression.. ...
  https://www.ncbi.nlm.nih.gov/pubmed/17415413
*  Recent Articles | Hearing And Disease/Medicine | The Scientist Magazine®| Page 6
A memory B cell response to Zika virus in dengue-infected patients produced antibodies that were poorly neutralizing in vitro ... Cows injected with a protein that mimics HIV's envelope make broadly neutralizing antibodies that inhibit multiple strains of ... Immunized Cows Produce Anti-HIV Antibodies. By Jef Akst , July 20, 2017 ...
  https://www.the-scientist.com/?articles.list/tagNo/1887,6/tags/hearing,disease-medicine/pageNo/6/