*  Fluorouracil, Leucovorin, and Oxaliplatin With or Without Bevacizumab in Treating Patients Who Have Undergone Surgery for Stage...
anti-VEGF humanized monoclonal antibody. *anti-VEGF monoclonal antibody. *Avastin. *rhuMAb VEGF ... Antibodies. Immunoglobulins. Antibodies, Monoclonal. Calcium, Dietary. Levoleucovorin. Angiogenesis Inhibitors. Angiogenesis ... Monoclonal antibodies such as bevacizumab can locate tumor cells and either kill them or deliver tumor-killing substances to ...
  https://clinicaltrials.gov/ct2/show/study/NCT00096278
*  Combination Chemotherapy With or Without Bevacizumab in Treating Patients Who Have Undergone Surgery for High Risk Stage II or...
Monoclonal antibodies, such as bevacizumab, can block tumor growth in different ways. Some block the ability of tumor cells to ... Patients with known allergy to Chinese hamster ovary cell proteins or other recombinant human or humanized antibodies or to any ...
  https://clinicaltrials.gov/ct2/show/study/NCT00112918?view=results
*  Herceptin (Trastuzumab): Side Effects, Interactions, Warning, Dosage & Uses
Herceptin (trastuzumab) is a humanized IgG1 kappa monoclonal antibody that selectively binds with high affinity to the ... For these reasons, comparison of the incidence of antibodies to Herceptin with the incidence of antibodies to other products ... Additionally, the observed incidence of antibody (including neutralizing antibody) positivity in an assay may be influenced by ... The incidence of antibody formation is highly dependent on the sensitivity and the specificity of the assay. ...
  https://www.rxlist.com/herceptin-drug.htm
*  DailyMed - Search Results for Antibodies, Monoclonal, Humanized
SEARCH RESULTS for: Antibodies, Monoclonal, Humanized [Drug Class] (3 results) * Share : JavaScript needed for Sharing tools. ...
  https://dailymed.nlm.nih.gov/dailymed/search.cfm?query=Antibodies,%20Monoclonal,%20Humanized&searchdb=class
*  PBEF Neutralizing Humanized Monoclonal Antibodies As Novel Therapeutic Approaches | SBIR.gov
PBEF Neutralizing Humanized Monoclonal Antibodies As Novel Therapeutic Approaches. Printer-friendly version ... and propose to generate therapeutic humanized neutralizing anti-PBEF monoclonal antibodies to treat patients with acute lung ... We therefore propose to generate humanized ant-PBEFmonoclonal antibodies (P- BEFizumab) that can be used as both prophylactic ... Once the credibility of these antibodies in treating patients with ALI/VILI is established, we believe that these antibodies ...
  https://www.sbir.gov/sbirsearch/detail/370178
*  Clinical Assessment of Safety and Tolerability of the New Monoclonal Humanized Antibody CaCP29 - Full Text View -...
Clinical Assessment of Safety and Tolerability of the New Monoclonal Humanized Antibody CaCP29. The safety and scientific ... The novel humanized monoclonal antibody CaCP29 was developed to control the inflammatory response to various stimuli in humans ... Intervention Details: Biological: CaCP29, a humanized monoclonal antibody CaCP29 or placebo single i.v. infusion in ascending ... Pharmacokinetics and Pharmacodynamics of the New Humanized Monoclonal Antibody CaCP29. ...
  https://www.clinicaltrials.gov/ct2/show/NCT01319903
*  A Phase II Study of Apolizumab, a Humanized Monoclonal Antibody, in Patients With Relapsed or Refractory Follicular, Small...
... is capable of inducing antibody-dependent cellular cytotoxicity, complement-mediated lysis, and direct apoptosis of lymphoma ... The humanized monoclonal antibody apolizumab (Remitogen, Hu1D10), directed against a polymorphic determinant of HLA-DR ... The humanized monoclonal antibody apolizumab (Remitogen, Hu1D10), directed against a polymorphic determinant of HLA-DR ... A Phase II Study of Apolizumab, a Humanized Monoclonal Antibody, in Patients With Relapsed or Refractory Follicular, Small ...
  http://www.cancernetwork.com/review-article/phase-ii-study-apolizumab-humanized-monoclonal-antibody-patients-relapsed-or-refractory-follicular
*  TAK-701, a Humanized Monoclonal Antibody to Hepatocyte Growth Factor, Reverses Gefitinib Resistance Induced by Tumor-Derived...
TAK-701, a humanized monoclonal antibody to HGF, in combination with gefitinib inhibited the phosphorylation of MET, EGFR, ... TAK-701, a Humanized Monoclonal Antibody to Hepatocyte Growth Factor, Reverses Gefitinib Resistance Induced by Tumor-Derived ... TAK-701, a Humanized Monoclonal Antibody to Hepatocyte Growth Factor, Reverses Gefitinib Resistance Induced by Tumor-Derived ... TAK-701, a Humanized Monoclonal Antibody to Hepatocyte Growth Factor, Reverses Gefitinib Resistance Induced by Tumor-Derived ...
  http://mct.aacrjournals.org/content/early/2010/09/17/1535-7163.MCT-10-0481
*  A Phase I Trial of Humanized Monoclonal Antibody A33 in Patients with Colorectal Carcinoma: Biodistribution, Pharmacokinetics,...
Immuno-PET of human colon xenograft-bearing BALB/c nude mice using 124I-CDR-grafted humanized A33 monoclonal antibody. J Nucl ... Phase II study of weekly intravenous recombinant humanized anti-p185HER2 monoclonal antibody in patients with HER2/neu- ... Phase II study of receptor-enhanced chemosensitivity using recombinant humanized anti-p185HER2/neu monoclonal antibody plus ... A phase 1B trial of humanized monoclonal antibody M195 (anti-CD33) in myeloid leukemia: specific targeting without ...
  http://clincancerres.aacrjournals.org/content/11/13/4810
*  Defining limits of treatment with humanized neutralizing monoclonal antibody for West Nile virus neurological infection in a...
... neutralizing humanized monoclonal antibody, hE16, was previously shown to improve the survival of WNV-infected hamsters when it ... A potent anti-West Nile virus (anti-WNV)-neutralizing humanized monoclonal antibody, hE16, was previously shown to improve the ... Defining limits of treatment with humanized neutralizing monoclonal antibody for West Nile virus neurological infection in a ... Antibodies, Monoclonal / administration & dosage*, blood, cerebrospinal fluid, therapeutic use*. Antiviral Agents / therapeutic ...
  http://www.biomedsearch.com/nih/Defining-limits-treatment-with-humanized/17452485.html
*  Abstract 3667: Reduction of in vivo tumor growth and angiogenesis by a humanized IgG4 monoclonal antibody to SEMA4D | Cancer...
Abstract 3667: Reduction of in vivo tumor growth and angiogenesis by a humanized IgG4 monoclonal antibody to SEMA4D. Alan S. ... Abstract 3667: Reduction of in vivo tumor growth and angiogenesis by a humanized IgG4 monoclonal antibody to SEMA4D ... Abstract 3667: Reduction of in vivo tumor growth and angiogenesis by a humanized IgG4 monoclonal antibody to SEMA4D ... Abstract 3667: Reduction of in vivo tumor growth and angiogenesis by a humanized IgG4 monoclonal antibody to SEMA4D ...
  http://cancerres.aacrjournals.org/content/71/8_Supplement/3667
*  Humanized 3F8 Monoclonal Antibody (Hu3F8) When Combined With Interleukin-2 in Patients With High-Risk Neuroblastoma and GD2...
... humanized 3F8' (Hu3F8) when combined with interleukin-2 (rIL2) is safe for treating neuroblastoma and othe ... Phase I Study of Humanized 3F8 Monoclonal Antibody (Hu3F8) When Combined With Interleukin-2 in Patients With High-Risk ... Phase I Study of Humanized 3F8 Monoclonal Antibody (Hu3F8) When Combined With Interleukin-2 in Patients With High-Risk ... or hu14.18 treatment must have HAHA antibody titer less than or = to 1300 Elisa. units/ml. - White blood cell count ≥1000/ul. ...
  http://www.knowcancer.com/cancer-trials/NCT01662804/
*  Patent US8088908 - Humanized anti-prostate stem cell antigen monoclonal antibody - Google Patents
Murine monoclonal antibody 1G8 binds to PSCA with nanomolar affinity, but its efficacy as a therapeutic agent is limited by the ... These humanized antibodies bind PSCA with high affinity and specificity, and have been shown to reduce human bladder tumor take ... The present invention discloses humanized 1G8 antibodies in which the majority of the mouse-derived epitopes have been removed ... These characteristics make the humanized antibodies of the present invention attractive agents for the treatment and detection ...
  http://www.google.co.uk/patents/US8088908
*  Humanized Monoclonal Antibodies to Hepatocyte Growth Factor - Patent application
A humanized antibody is a genetically engineered (monoclonal) antibody in which the CDRs from a mouse antibody ("donor antibody ... donor antibody is also transferred to the humanized antibody. Thus, a humanized antibody is an antibody having CDRs from a ... antibody reduce or eliminate binding of the other. 2. Humanized Neutralizing Anti-HGF Antibodies [0029]A monoclonal antibody ( ... A humanized monoclonal antibody (mAb) that binds and neutralizes human Hepatocyte Growth Factor (HGF), the humanized antibody ...
  http://www.patentsencyclopedia.com/app/20100278815
*  Targeted Atomic Nano-Generators (Actinium-225-Labeled Humanized Anti-CD33 Monoclonal Antibody HuM195) in Patients With Advanced...
Biological: ACTINIUM-225-LABELED HUMANIZED ANTI-CD33 MONOCLONAL ANTIBODY HuM195 A single infusion of 225Ac-HuM195 will be ... Phase I Trial of Targeted Atomic Nano-Generators (Actinium-225-Labeled Humanized Anti-CD33 Monoclonal Antibody HuM195) in ... Targeted Atomic Nano-Generators (Actinium-225-Labeled Humanized Anti-CD33 Monoclonal Antibody HuM195) in Patients With Advanced ... Biological: ACTINIUM-225-LABELED HUMANIZED ANTI-CD33 MONOCLONAL ANTIBODY HuM195 Phase 1 ...
  https://clinicaltrials.gov/show/NCT00672165
*  Apoptosis Induction of Human Lung Cancer Cell Line in Multicellular Heterospheroids with Humanized Antiganglioside GM2...
Construction and characterization of a humanized anti-ganglioside GM2 monoclonal antibody, submitted for publication. ... Takamuku K., Akiyoshi T., Tsuji H. Antibody-dependent cell-mediated cytotoxicity using a murine monoclonal antibody against ... A humanized anti-tumor necrosis factor-monoclonal antibody that acts as a partial, competitive antagonist of the template ... Antibody Treatment of Heterospheroids.. The heterospheroids (n = 10) were incubated with the humanized KM8969 from day 2 to day ...
  http://cancerres.aacrjournals.org/content/59/20/5323
*  Safety, Efficacy and pharmacokinetics of T1h, a humanized anti-CD6 monoclonal antibody, in moderate to severe chronic plaque...
T1h, a novel humanized monoclonal antibody targeting CD6, a co-stimulatory receptor present on T cells, was evaluated as a ... Safety, Efficacy and pharmacokinetics of T1h, a humanized anti-CD6 monoclonal antibody, in moderate to severe chronic plaque ... Safety, Efficacy and pharmacokinetics of T1h, a humanized anti-CD6 monoclonal antibody, in moderate to severe chronic plaque ... Safety, Efficacy and pharmacokinetics of T1h, a humanized anti-CD6 monoclonal antibody, in moderate to severe chronic plaque ...
  http://www.jimmunol.org/content/184/1_Supplement/96.13
*  A Phase 1/2, Multi-center, Open-label, Dose-escalation Study of Elotuzumab(Humanized Anti-CS1 Monoclonal IgG1 Antibody) and...
A Phase 1/2, Multi-center, Open-label, Dose-escalation Study of Elotuzumab(Humanized Anti-CS1 Monoclonal IgG1 Antibody) and ... A Phase 1/2, Multi-center, Open-label, Dose-escalation Study of Elotuzumab(Humanized Anti-CS1 Monoclonal IgG1 Antibody) and ... Nitrogen mustard agents, melphalan, or monoclonal antibodies within 6 weeks of the first dose of elotuzumab. ... Incidence of elotuzumab-specific antidrug antibodies. *Evaluate the pharmacodynamics of elotuzumab in combination with ...
  https://clinicaltrials.gov/ct2/show/NCT00726869
*  First-in-Human Phase I Study of Lumretuzumab, a Glycoengineered Humanized Anti-HER3 Monoclonal Antibody, in Patients with...
First-in-Human Phase I Study of Lumretuzumab, a Glycoengineered Humanized Anti-HER3 Monoclonal Antibody, in Patients with ... First-in-Human Phase I Study of Lumretuzumab, a Glycoengineered Humanized Anti-HER3 Monoclonal Antibody, in Patients with ... First-in-Human Phase I Study of Lumretuzumab, a Glycoengineered Humanized Anti-HER3 Monoclonal Antibody, in Patients with ... First-in-Human Phase I Study of Lumretuzumab, a Glycoengineered Humanized Anti-HER3 Monoclonal Antibody, in Patients with ...
  http://clincancerres.aacrjournals.org/content/22/4/877
*  A Pilot Trial of Humanized Anti-GD2 Monoclonal Antibody (hu14.18K322A) with Chemotherapy and Natural Killer Cells in Children...
A Pilot Trial of Humanized Anti-GD2 Monoclonal Antibody (hu14.18K322A) with Chemotherapy and Natural Killer Cells in Children ... A Pilot Trial of Humanized Anti-GD2 Monoclonal Antibody (hu14.18K322A) with Chemotherapy and Natural Killer Cells in Children ... A Pilot Trial of Humanized Anti-GD2 Monoclonal Antibody (hu14.18K322A) with Chemotherapy and Natural Killer Cells in Children ... A Pilot Trial of Humanized Anti-GD2 Monoclonal Antibody (hu14.18K322A) with Chemotherapy and Natural Killer Cells in Children ...
  http://clincancerres.aacrjournals.org/content/early/2017/10/05/1078-0432.CCR-17-0379.article-info
*  Phase I study of ontuxizumab, a humanized monoclonal antibody recognizing endosialin/tumor endothelial marker1 (TEM1), in...
Ontuxizumab is humanized immunoglobulin G-1-kappa (IgG1/κ) monoclonal antibody that is the first clinical-stage agent to target ... Phase I study of ontuxizumab, a humanized monoclonal antibody recognizing endosialin/tumor endothelial marker1 (TEM1), in ... 458P - Phase I study of ontuxizumab, a humanized monoclonal antibody recognizing endosialin/tumor endothelial marker1 (TEM1), ... Human anti-human antibody was not detected. Of eight pts with stable disease, one pt with GIST after failure of imatinib and ...
  http://oncologypro.esmo.org/Topics/Anti-Cancer-Agents-Biologic-Therapy/Drug-Development/Phase-I-study-of-ontuxizumab-a-humanized-monoclonal-antibody-recognizing-endosialin-tumor-endothelial-marker1-TEM1-in-Japanese-patients-with-solid-tumor
*  Radiobromination of humanized anti-HER2 monoclonal antibody trastuzumab using N-succinimidyl 5-bromo-3-pyridinecarboxylate, a...
For internalizing antibodies, such as the humanized anti-HER2 monoclonal antibody, trastuzumab, radiobromine label should be ... Radiobromination of humanized anti-HER2 monoclonal antibody trastuzumab using N-succinimidyl 5-bromo-3-pyridinecarboxylate, a ... Positron-emitting nuclide (76)Br (T(1/2)=16.2 h) might be a possible candidate for labeling monoclonal antibodies (mAbs) and ... The third and final section describes the indirect radiobromination of the trastuzumab anti-HER2 monoclonal antibody and of the ...
  http://uu.diva-portal.org/smash/record.jsf?pid=diva2:219917
*  Trastuzumab (Herceptin), a Humanized Anti-HER2 Receptor Monoclonal Antibody, Inhibits Basal and Activated HER2 Ectodomain...
Trastuzumab (Herceptin), a Humanized Anti-HER2 Receptor Monoclonal Antibody, Inhibits Basal and Activated HER2 Ectodomain ... Trastuzumab (Herceptin), a Humanized Anti-HER2 Receptor Monoclonal Antibody, Inhibits Basal and Activated HER2 Ectodomain ... Trastuzumab (Herceptin), a Humanized Anti-HER2 Receptor Monoclonal Antibody, Inhibits Basal and Activated HER2 Ectodomain ... Trastuzumab (Herceptin), a Humanized Anti-HER2 Receptor Monoclonal Antibody, Inhibits Basal and Activated HER2 Ectodomain ...
  http://cancerres.aacrjournals.org/content/61/12/4744
*  Fremanezumab - a humanized monoclonal anti-CGRP antibody - inhibits thinly myelinated (Aδ) but not unmyelinated (C) meningeal...
Fremanezumab - a humanized monoclonal anti-CGRP antibody - inhibits thinly myelinated (Aδ) but not unmyelinated (C) meningeal ... Fremanezumab - a humanized monoclonal anti-CGRP antibody - inhibits thinly myelinated (Aδ) but not unmyelinated (C) meningeal ... Home , Papers , Fremanezumab - a humanized monoclonal anti-CGRP antibody - inhibits thinly myelinated (Aδ) but not unmyelinated ...
  http://www.painresearchforum.org/papers/87032-fremanezumab-humanized-monoclonal-anti-cgrp-antibody-inhibits-thinly-myelinated-a%CE%B4-not
*  Oral Immunotherapy Combined With Humanized Monoclonal Anti-IgE Antibody Xolair® (Omalizumab)in the Treatment of Cow's Milk...
This trial is investigating Oral Immunotherapy Combined With Humanized Monoclonal Anti-IgE Antibody Xolair® (Omalizumab)in the ... Oral Immunotherapy Combined With Humanized Monoclonal Anti-IgE Antibody Xolair® (Omalizumab)in the Treatment of Cow's Milk ... Oral Immunotherapy Combined With Humanized Monoclonal Anti-IgE Antibody Xolair® (Omalizumab)in the Treatment of Cow's Milk ...
  https://adisinsight.springer.com/trials/700263483?error=cookies_not_supported&code=7ec556cd-3e70-49bf-8439-2b06c512df44