*  Case Reports - Reviews sub-cluster 70

A case of double aneuploidy involving chromosome 21 and Y is reported in an eight-month-old infant with developmental delay and ... The 48, XXY/+18 is a very rare aneuploidy syndrome which combines the aberration in both autosome and sex chromosome. The ...

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39). Like all TGCTs, seminomas are characterized by high levels of CIN and aneuploidy, and a gain of chromosome 12p (46). Gain ...

*  Use of Ciliogenesis to Detect Aneugens: The Role of Primary Cilia - Current Protocols

Centrosomal amplification and aneuploidy induced by the antiretroviral drug AZT in hamster and human cells. Mutat. Res. 665:67‐ ... The detection and assessment of the aneugenic potential of environmental chemicals: The European Community Aneuploidy Project. ... Genomic instability induced by AZT in cultured normal human mammary epithelial cells (NHMECs) generates aneuploidy. ...

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2008). Mice with a defect in the related SAC component Bub1 also show increased aneuploidy and premature senescence, yet these ... 2006). Mice with a severe reduction in BubR1 (BubR1 hypomorphic mice) show progressive aneuploidy and several symptoms of ... 2004). A reduction in BubR1 levels in mouse embryonic fibroblasts caused increased aneuploidy and senescence. In agreement with ... SAC failure can result in aneuploidy, a deviation from normal chromosome numbers that is often linked to tumorigenesis. However ...

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However, studies from rodents suggest that BPA can cause aneuploidy in oocytes (Susiarjo et al. 2007) and alter the body weight ...

*  Prevalence of Y chromosome microdeletions in oligospermic and azoospermic candidates for intracytoplasmic sperm injection. |...

Two of the azoospermic patients with a Yq microdeletion also had sex chromosome aneuploidy mosaicism. ...

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It was on mitosis, meiosis, nondisjunction, aneuploidy, mutations, genetic diseases, DNA replication, transcription, and ...

*  Global DNA hypomethylation (LINE-1) in the normal colon and lifestyle characteristics and dietary and genetic factors. -...

Global loss of methylated cytosines in DNA, thought to predispose to chromosomal instability and aneuploidy, has been ...

*  Estudios cariotípicos en el género chileno Placea (Amaryllidaceae)

The sof chromosome number in genus Placea suggests that neither polyploidy nor aneuploidy nor dysploidy have played a ...

*  Early embryos can correct genetic abnormalities during d... ( Professor William G. Kearns told the...)

A current challenge within stem cell biology is the high rate of acquired aneuploidy that is observed with cell colonies in ... "aneuploidy") was capable of undergoing "a dynamic process of genetic normalisation" so that by day five, when it had developed ...

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Gene expression profiling reveals a massive, aneuploidy-dependent transcriptional deregulation and distinct differences between ...

*  Glossary: Story - Cancer Forums and News

aneuploidy. Detailed definition. angiocidin. Detailed definition. angiogenesis. Detailed definition. angiotensin. Detailed ...

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Aneuploidy causes tissue-specific qualitative changes in global gene expression patterns in maize... Makarevitch I, Harris C.. ...

*  Mitochondrial dysfunction in oocytes of obese mothers: transmission to offspring and reversal by pharmacological endoplasmic...

2012). High fat diet induced developmental defects in the mouse: oocyte meiotic aneuploidy and fetal growth retardation/brain ...

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... miscarriage and aneuploidy. ...

*  Could a New Down Syndrome Mouse Model Also Be Useful for Alzheimer Research? | ALZFORUM

... it does look as if there's aneuploidy in the normal human brain (see Rehen et al., 2001). We guess it might be difficult to get ...

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... and aneuploidy. These phenomena may be ascribed to the role that BRCA1 is thought to play in maintaining genomic integrity (1 ...

*  Toward the future of cancer prevention | EurekAlert! Science News

A molecular marker, aneuploidy (an abnormal amount of chromosomes in a cell), signals the risk of these people, "highlighting ...

*  The Thyroid Hurthle (Oncocytic) Cell and Its Associated Pathologic Conditions: A Surgical Pathology and Cytopathology Review -...

... this technique cannot discriminate between benign and malignant Hurthle cell neoplasms because adenomas may show aneuploidy and ...

*  Experiments | The Embryo Project Encyclopedia

Using Digital PCR to Detect Fetal Chromosomal Aneuploidy in Maternal Blood (2007) Meilin Zhu In 2007, Dennis Lo and his ... validating the method as a means to detect fetal chromosomal aneuploidies, or an abnormal number of chromosomes in a cell. The ...

*  New Guidance on Genetic and Genomic Testing - AACC.org

... non-invasive prenatal screening for fetal aneuploidy (NIPS) and reporting incidental findings from whole exome or genome ... In a policy statement on NIPS, ACMG noted that analyzing cell-free fetal DNA from maternal blood for fetal aneuploidy is likely ... However, ACMG cited 10 limitations of NIPS, including: identifying only three aneuploidies-leaving undetected about half those ... non-invasive prenatal screening for fetal aneuploidy (NIPS) and reporting incidental findings from whole exome or genome ...

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Worse: t(4;14), MAF translocations t(14;16) and t(14;20), del(17p), del 13, aneuploidy, hypodiploidy * Better: hyperdiploid, t( ...

*  mutation | genetics | Britannica.com

Loss or gain of whole chromosomes results in a condition called aneuploidy. One familiar result of aneuploidy is Down syndrome ...

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"HET/SAF-B overexpression causes growth arrest and multinuclearity and is associated with aneuploidy in human breast cancer," ...

*  Molecules | Free Full-Text | Evaluation of Deoxyribonucleic Acid Toxicity Induced by the Radiopharmaceutical 99mTechnetium...

... which induce aneuploidy or abnormal chromossomic segregation) agents. The capacity to identify cells with a chromossomic defect ...