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Correction: In "Diabetes-Associated SorCS1 Regulates Alzheimers Amyloid-β Metabolism: Evidence for Involvement of SorL1 and ... Correction for Rachel F. Lane et al., "Diabetes-Associated SorCS1 Regulates Alzheimers Amyloid-β Metabolism: Evidence for ... Correction for Rachel F. Lane et al., "Diabetes-Associated SorCS1 Regulates Alzheimers Amyloid-β Metabolism: Evidence for ... Correction for Rachel F. Lane et al., "Diabetes-Associated SorCS1 Regulates Alzheimers Amyloid-β Metabolism: Evidence for ...
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A major plaque component, β amyloid peptide (Aβ), derives from the amyloid precursor protein (APP). Human genetics supports the ... 2013) Amyloid-β oligomer detection by ELISA in cerebrospinal fluid and brain tissue. Anal Biochem 433:112-120, doi:10.1016/j.ab ... 2013) Evaluating amyloid-β oligomers in cerebrospinal fluid as a biomarker for Alzheimers disease. PLoS One 8:e66381, doi: ... 2013) Amyloid-beta oligomerization in Alzheimer dementia versus high-pathology controls. Ann Neurol 73:104-119, doi:10.1002/ana ...
Neurexin-β Mediates the Synaptogenic Activity of Amyloid Precursor Protein Vedrana Cvetkovska, Yuan Ge, Qin Xu, Shaokun Li, ...
Assays for serum amyloid A (SAA), α2 antiplasmin (α2-AP), and complement 3 (C3) were performed as described previously ( ... Bharadwaj D, Mold C, Markham E, Du Clos TW (2001) Serum amyloid P component binds to Fc gamma receptors and opsonizes particles ... Mold C, Baca R, Du Clos TW (2002a) Serum amyloid P component and C-reactive protein opsonize apoptotic cells for phagocytosis ... Price DL, Borchelt DR, Sisodia SS (1993) Alzheimer disease and the prion disorders amyloid beta-protein and prion protein ...
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SORLA directs APP away from endosomes, preventing excess production of β-amyloid. Disruption of this role likely explains why ... Loss of this regenerative function might exacerbate the detrimental effects of increased β-amyloid production when SORLA ... Cargoes guided by SORLA include amyloid precursor protein (APP), which is processed in different cellular compartments to ... produce β-amyloid and/or other cleavage products. ...
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Reduced Alzheimers Disease β-Amyloid Deposition in Transgenic Mice Expressing S-Palmitoylation-Deficient APH1aL and Nicastrin ...
The glymphatic pathway expedites clearance of waste, including soluble amyloid β (Aβ) from the brain. Transport through this ...
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Fibrillar Amyloid-β-Activated Human Astroglia Kill Primary Human Neurons via Neutral Sphingomyelinase: Implications for ...
Robust Amyloid Clearance in a Mouse Model of Alzheimers Disease Provides Novel Insights into the Mechanism of Amyloid-β ... Correction for Rachel F. Lane et al., "Diabetes-Associated SorCS1 Regulates Alzheimers Amyloid-β Metabolism: Evidence for ...
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β-Amyloid-Stimulated Microglia Induce Neuron Death via Synergistic Stimulation of Tumor Necrosis Factor α and NMDA Receptors ... Certain Inhibitors of Synthetic Amyloid β-Peptide (Aβ) Fibrillogenesis Block Oligomerization of Natural Aβ and Thereby Rescue ...
... with a potential connection between the DMN metabolic rate and amyloid deposition (Buckner et al., 2005, 2009), it may be also ...
β-Amyloid Stimulation of Microglia and Monocytes Results in TNFα-Dependent Expression of Inducible Nitric Oxide Synthase and ... Use-Dependent Effects of Amyloidogenic Fragments of β-Amyloid Precursor Protein on Synaptic Plasticity in Rat Hippocampus In ...