*  A linkage analysis toolkit for studying allosteric networks in ion channels | JGP
... has achieved impressive insight into its allosteric machinery (Eaton et al., 2007). A K+ channel whose regulation, at a basic ... Modality-sensitive allosteric factors. Constraint 4 implied that allosteric energies are insensitive to external forces. There ... model as a natural choice for allosteric regulation of BK.. The relatively large number of regulatory domains (four voltage ... Allosteric interactions are labeled C, D, and E. (B) Five linkage cycles generated from the work functions WC[q] and WH[g] and ...
  http://jgp.rupress.org/content/early/2012/12/11/jgp.201210859
*  Plus it
Allosteric operational model parameters for the functional allosteric interaction between flavonols and peptide ligands of the ... but is not under direct regulation by estradiol, 17beta-diol, or dihydrotestosterone in breast cancer cells ... Recent drug discovery efforts for the GLP-1R have focused on targeting sites for allosteric modulation. Allosteric interactions ... 2007) Allosteric GPCR modulators: taking advantage of permissive receptor pharmacology. Trends Pharmacol Sci 28:382-389. ...
  http://jpet.aspetjournals.org/content/336/2/540
*  Allosteric regulation - Wikipedia
In biochemistry, allosteric regulation (or allosteric control) is the regulation of an enzyme by binding an effector molecule ... B - Allosteric site. C - Substrate. D - Inhibitor. E - Enzyme. This is a diagram of allosteric regulation of an enzyme. ... Ensemble models of allosteric regulation enumerate an allosteric system's statistical ensemble as a function of its potential ... allosteric regulation is also expected to play an increasing role in drug discovery and bioengineering. The AlloSteric Database ...
  https://en.wikipedia.org/wiki/Homotropic_allosteric_interaction
*  Definition of allosteric regulation - Chemistry Dictionary
Definition of allosteric regulation. 1) Allosteric regulation is the regulation of the activity of allosteric enzymes. (See ...
  http://www.chemistry-dictionary.com/definition/allosteric+regulation.php
*  Duke Physics
Balabin, IA; Yang, W; Beratan, DN, Coarse-grained modeling of allosteric regulation in protein receptors., Proceedings of the ... Allosteric regulation provides highly specific ligand recognition and signaling by transmembrane protein receptors. Unlike ... We describe a theoretical model for allosteric regulation in receptors that addresses a fundamental riddle of signaling: What ...
  http://fds.duke.edu/db/aas/Physics/faculty/weitao.yang/publications/235009
*  Prepaying the entropic cost for allosteric regulation in KIX | PNAS
Prepaying the entropic cost for allosteric regulation in KIX. Sean M. Law, Jessica K. Gagnon, Anna K. Mapp and Charles L. ... Our results capture an increase in affinity for the peptide in the allosteric site when KIX is prebound by a complementary ... Here, we investigate the allosteric mechanism involving a promiscuous protein that serves as a hub for a variety of ... It is presumable that the features identified in this allosteric mechanism are conserved between the central protein and other ...
  http://www.pnas.org/content/early/2014/07/02/1405831111
*  Targeting PARP-1 Allosteric Regulation Offers Therapeutic Potential against Cancer | Cancer Research
Targeting PARP-1 Allosteric Regulation Offers Therapeutic Potential against Cancer. Jamin D. Steffen, Renee M. Tholey, Marie- ... Targeting PARP-1 Allosteric Regulation Offers Therapeutic Potential against Cancer. Jamin D. Steffen, Renee M. Tholey, Marie- ... Targeting PARP-1 Allosteric Regulation Offers Therapeutic Potential against Cancer. Jamin D. Steffen, Renee M. Tholey, Marie- ... Targeting PARP-1 Allosteric Regulation Offers Therapeutic Potential against Cancer Message Subject (Your Name) has forwarded a ...
  http://cancerres.aacrjournals.org/content/74/1/31
*  Allosteric regulation - Wikipedia
In biochemistry, allosteric regulation (or allosteric control) is the regulation of an enzyme by binding an effector molecule ... Ensemble models of allosteric regulation enumerate an allosteric system's statistical ensemble as a function of its potential ... the allosteric site). The sequential model of allosteric regulation holds that subunits are not connected in such a way that a ... allosteric regulation is also expected to play an increasing role in drug discovery and bioengineering. The AlloSteric Database ...
  https://en.wikipedia.org/wiki/Allosteric_regulation
*  Hemoglobin function and allosteric regulation in semi-fossorial rodents (family Sciuridae) with different altitudinal ranges. ...
Hemoglobin function and allosteric regulation in semi-fossorial rodents (family Sciuridae) with different altitudinal ranges.. ... Hemoglobin function and allosteric regulation in semi-fossorial rodents (family Sciuridae) with different altitudinal ranges ... Hemoglobin function and allosteric regulation in semi-fossorial rodents (family Sciuridae) with different altitudinal ranges ... Hemoglobin function and allosteric regulation in semi-fossorial rodents (family Sciuridae) with different altitudinal ranges ...
  https://www.ncbi.nlm.nih.gov/pubmed/24172889
*  Novel ATP-cone-driven allosteric regulation of ribonucleotide reductase via the radical-generating subunit | eLife
Structural and functional characterization of an unanticipated mode of allosteric activity regulation in ribonucleotide ... This type of allosteric regulation has been shown to provide an evolutionarily dynamic process by which allosteric regulation ... Allosteric regulation of an enzyme is defined as regulation of activity by binding of an effector molecule to a different ... Allosteric regulation of RNRs affects both substrate specificity and overall activity. The specificity regulation has been ...
  https://elifesciences.org/articles/31529
*  Familial and Somatic BAP1 Mutations Inactivate ASXL1/2-Mediated Allosteric Regulation of BAP1 Deubiquitinase by Targeting...
Familial and Somatic BAP1 Mutations Inactivate ASXL1/2-Mediated Allosteric Regulation of BAP1 Deubiquitinase by Targeting ... Familial and Somatic BAP1 Mutations Inactivate ASXL1/2-Mediated Allosteric Regulation of BAP1 Deubiquitinase by Targeting ... Familial and Somatic BAP1 Mutations Inactivate ASXL1/2-Mediated Allosteric Regulation of BAP1 Deubiquitinase by Targeting ... Familial and Somatic BAP1 Mutations Inactivate ASXL1/2-Mediated Allosteric Regulation of BAP1 Deubiquitinase by Targeting ...
  http://cancerres.aacrjournals.org/content/early/2017/12/28/0008-5472.CAN-17-2876.article-info
*  L0710ap - committed step in a pathway Allosteric regulation(mechanism Binding of ATP to a non-substrate(allosteric site on the...
committed step in a pathway Allosteric regulation (mechanism) Binding of ATP to a non-substrate (allosteric) site on the enzyme ... committed step in a pathway Allosteric regulation (mechanism) Binding of ATP to a non-substrate (allosteric) site on the enzyme ... Regulation of Glycolysis Learning Objectives: List the points of regulation in glyco ... Net reaction rate is: Inhibited by ↑ATP Accelerated by ↑ADP Feedback regulation (principle) End products of biochemical ...
  https://www.coursehero.com/file/6123813/L0710ap/
*  Enzyme Inhibition - Types of Inhibition - Allosteric Regulation - TeachMePhysiology
Allosteric Inhibition. Allosteric enzymes display a sigmoidal curve in contrast to the hyperbolic curve displayed by Michaelis- ... How do allosteric inhibitors usually work? Bind to R state to maintain low affinity state of enzyme Bind to R state to maintain ... Allosteric enzymes have two states: a low affinity state dubbed the "T" state and the high affinity "R" state. Inhibitors work ... This is because most allosteric enzymes contain multiple sub-units which can affect each other when the substrate binds to the ...
  http://teachmephysiology.com/basics/enzyme-activity/enzyme-inhibition/
*  Receptor disulfide allosteric regulation of anthrax toxin action - Jianjun Sun
Receptor disulfide allosteric regulation of anthrax toxin action Sun, Jianjun University of Texas El Paso, El Paso, TX, United ... Receptor disulfide allosteric regulation of anthrax toxin action. Sun, Jianjun / University of Texas El Paso. $224,250. ... Receptor disulfide allosteric regulation of anthrax toxin action. Sun, Jianjun / University of Texas El Paso. $224,250. ... Receptor disulfide allosteric regulation of anthrax toxin action. Sun, Jianjun / University of Texas El Paso. $216,401. ...
  http://grantome.com/grant/NIH/SC1-GM095475-03
*  Postdoctoral Position - Allosteric Regulation in the KDM5 Family of Histone Demethylases | ISMAR
Postdoctoral Position - Allosteric Regulation in the KDM5 Family of Histone Demethylases. Submitted by mariabaias on Thu, 2015- ... Postdoctoral Position - Allosteric Regulation in the KDM5 Family of Histone Demethylases. *Postdoctoral Position Available in ... Postdoctoral Position - Allosteric Regulation in the KDM5 Family of Histone Demethylases. *Postdoctoral Position Available in ... The goal of this work is to expand our understanding of the mechanisms that underlie regulation of chromatin methylation and ...
  https://wws.weizmann.ac.il/ISMAR/positions/postdoctoral-position-allosteric-regulation-kdm5-family-histone-demethylases
*  Evidence for a Common Mechanism of SIRT1 Regulation by Allosteric Activators | Science
Evidence for a Common Mechanism of SIRT1 Regulation by Allosteric Activators. By Basil P. Hubbard, Ana P. Gomes, Han Dai, Jun ... Evidence for a Common Mechanism of SIRT1 Regulation by Allosteric Activators. By Basil P. Hubbard, Ana P. Gomes, Han Dai, Jun ... Evidence for a Common Mechanism of SIRT1 Regulation by Allosteric Activators Message Subject. (Your Name) has forwarded a page ... Thus, SIRT1 can be directly activated through an allosteric mechanism common to chemically diverse STACs. ...
  http://science.sciencemag.org/content/339/6124/1216.long
*  Molecular basis for allosteric specificity regulation in class Ia ribonucleotide reductase from Escherichia coli | eLife
Allosteric activity sites are shown with ATP modeled in cyan and dATP in red spheres. (E) Allosteric specificity regulation is ... First, allosteric activity regulation modulates the overall size of dNTP pools. ATP or dATP binding at an allosteric activity ... The second form of allosteric regulation is specificity regulation, which maintains the proper relative ratios of dNTPs in the ... Allosteric activity regulation is achieved by interconversion between an active α2β2 complex in the presence of the allosteric ...
  https://elifesciences.org/articles/07141
*  Lack of conventional oxygen-linked proton and anion binding sites does not impair allosteric regulation of oxygen binding in...
Lack of conventional oxygen-linked proton and anion binding sites does not impair allosteric regulation of oxygen binding in ...
  http://www.forskningsdatabasen.dk/catalog/243980667
*  Allosteric regulation of the partitioning of glucose-1-phosphate between glycogen and trehalose biosynthesis in Mycobacterium...
Allosteric regulation of the partitioning of glucose-1-phosphate between glycogen and trehalose biosynthesis in Mycobacterium ... None of the other two enzymes tested exhibited allosteric regulation. Conclusions: Results give information about how the ... The substrate specificity, kinetic parameters and allosteric regulation of each enzyme were determined. ADP-glucose ... Allosteric regulation of the partitioning of glucose-1-phosphate between glycogen and trehalose biosynthesis in Mycobacterium ...
  http://ri.conicet.gov.ar/handle/11336/39604
*  How Many Chromosomes Are Contained in a Human Male Gamete Cell? | Reference.com
What Is an Allosteric Regulation?. * Q: What Do You Call a Motor Neuron and All of the Skeletal Muscle Cells It Stimulates?. ...
  https://www.reference.com/science/many-chromosomes-contained-human-male-gamete-cell-8dfd2ddc668f1bff
*  biophysics | Philosophical Transactions of the Royal Society B: Biological Sciences
Markov models for the elucidation of allosteric regulation. Ushnish Sengupta, Birgit Strodel ... Folding cooperativity and allosteric function in the tandem-repeat protein class. Albert Perez-Riba, Marie Synakewicz, Laura S ... Ensemble allosteric model: energetic frustration within the intrinsically disordered glucocorticoid receptor. Jordan T. White, ... Shared dynamics of LeuT superfamily members and allosteric differentiation by structural irregularities and multimerization. ...
  http://rstb.royalsocietypublishing.org/collection/biophysics
*  Functional Subunits of Eukaryotic Chaperonin CCT/TRiC in Protein Folding
Allosteric Regulations in CCT. Allosteric regulation plays an important role for transitions between different functional ... Reissmann S, Parnot C, Booth CR, Chiu W, Frydman J. Essential function of the built-in lid in the allosteric regulation of ... As it was strongly believed that allosteric regulation of chaperonins is crucial for assisting the protein folding, the ... The allosteric transitions of GroEL can be described by a nested allosteric model in which each of its rings is in equilibrium ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC3268035/?lang=en-ca
*  Kimberlite
Allosteric regulation. Aqueous solution. Tabun (nerve agent). Liquid hydrogen. Alanine. Nutrient. Plasmolysis. ...
  https://www.princeton.edu/~achaney/tmve/wiki100k/docs/Kimberlite.html
*  button what time should you take spironolactone point that
Drug regulations require that safety, spironolacton, and quality of the product are defined, whereas food regulations are less ... The allosteric effect was thus assumed to be mediated entirely by the enzyme molecule and to depend upon its specific structure ...
  http://luxbar-starway.ru/cheap-meds-online-no-prescription/what-time-should-you-take-spironolactone.html
*  Protocols and Video Articles Authored by Rohini Kuner (Translated to Italian)
Regulation of Motor Performance and Striatal Function by Synaptic Scaffolding Proteins of the Homer1 Family Proceedings of the ... However, the positive allosteric GABA(A) receptor modulator diazepam (DZP) had almost completely lost its potentiating effect ... This process was mediated by activation of PKC-delta via Gab1/2/PI(3)K and subsequent regulation of TRPV1, a member of the ... These results suggest that synapsin II is involved in the regulation of glutamate and GABA release in the spinal cord after ...
  https://www.jove.com/author/Rohini_Kuner?language=Italian