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*  Functional analysis of conserved histidines in ADP-glucose pyrophosphorylase from Escherichia coli. - Semantic Scholar
Identification of regions critically affecting kinetics and allosteric regulation of the Escherichia coli ADP-glucose ... A Novel Dual Allosteric Activation Mechanism of Escherichia coli ADP-Glucose Pyrophosphorylase: The Role of Pyruvate. *Matías D ...
  https://www.semanticscholar.org/paper/Functional-analysis-of-conserved-histidines-in-ADP-Hill-Preiss/14056a7c74bf62a66d9acb771c2bd24e1a8ed4b4
*  Allosteric regulation - Wikipedia
In biochemistry, allosteric regulation (or allosteric control) is the regulation of an enzyme by binding an effector molecule ... B - Allosteric site. C - Substrate. D - Inhibitor. E - Enzyme. This is a diagram of allosteric regulation of an enzyme. ... Ensemble models of allosteric regulation enumerate an allosteric system's statistical ensemble as a function of its potential ... allosteric regulation is also expected to play an increasing role in drug discovery and bioengineering. The AlloSteric Database ...
  https://en.wikipedia.org/wiki/Homotropic_allosteric_interaction
*  Allosteric regulation - Wikipedia
In biochemistry, allosteric regulation (or allosteric control) is the regulation of an enzyme by binding an effector molecule ... Ensemble models of allosteric regulation enumerate an allosteric system's statistical ensemble as a function of its potential ... the allosteric site). The sequential model of allosteric regulation holds that subunits are not connected in such a way that a ... allosteric regulation is also expected to play an increasing role in drug discovery and bioengineering. The AlloSteric Database ...
  https://en.wikipedia.org/wiki/Allosteric_regulation
*  Prepaying the entropic cost for allosteric regulation in KIX | PNAS
Prepaying the entropic cost for allosteric regulation in KIX. Sean M. Law, Jessica K. Gagnon, Anna K. Mapp and Charles L. ... Our results capture an increase in affinity for the peptide in the allosteric site when KIX is prebound by a complementary ... Here, we investigate the allosteric mechanism involving a promiscuous protein that serves as a hub for a variety of ... It is presumable that the features identified in this allosteric mechanism are conserved between the central protein and other ...
  http://www.pnas.org/content/early/2014/07/02/1405831111
*  PLOS Computational Biology: Binding Leverage as a Molecular Basis for Allosteric Regulation
... emphasizing that both enzymatic function and allosteric regulation require a coupling between ligand binding and protein ... Finally, sites with high binding leverage but no known biological function could be latent allosteric sites, and thus drug ... We show that high binding leverage is a characteristic of both allosteric sites and catalytic sites, ... Author Summary Allosteric protein regulation is the mechanism by which binding of a molecule to one site in a protein affects ...
  https://journals.plos.org/ploscompbiol/article/figure?id=10.1371/journal.pcbi.1002148.t002
*  Allosteric regulation of rhomboid intramembrane proteolysis | The EMBO Journal
Allosteric regulation is an efficient mechanism for modulation and regulation of protein activity to prevent non‐specific ... Allosteric regulation of rhomboid intramembrane proteolysis. Elena Arutyunova, Pankaj Panwar, Pauline M Skiba, Nicola Gale, ... Traut TW (1994) Dissociation of enzyme oligomers: a mechanism for allosteric regulation. Crit Rev Biochem Mol Biol 29: 125-163 ... The regulation of substrate binding and enzymatic activity for many serine proteases is achieved by allosteric interactions. ...
  http://emboj.embopress.org/content/33/17/1869?ijkey=dcc7e9b7a040c6b653ec87d4358438ba85f2c5b6&keytype2=tf_ipsecsha
*  Targeting PARP-1 Allosteric Regulation Offers Therapeutic Potential against Cancer | Cancer Research
Targeting PARP-1 Allosteric Regulation Offers Therapeutic Potential against Cancer. Jamin D. Steffen, Renee M. Tholey, Marie- ... Targeting PARP-1 Allosteric Regulation Offers Therapeutic Potential against Cancer. Jamin D. Steffen, Renee M. Tholey, Marie- ... Targeting PARP-1 Allosteric Regulation Offers Therapeutic Potential against Cancer. Jamin D. Steffen, Renee M. Tholey, Marie- ... Targeting PARP-1 Allosteric Regulation Offers Therapeutic Potential against Cancer Message Subject (Your Name) has forwarded a ...
  http://cancerres.aacrjournals.org/content/74/1/31
*  Hemoglobin function and allosteric regulation in semi-fossorial rodents (family Sciuridae) with different altitudinal ranges. ...
Hemoglobin function and allosteric regulation in semi-fossorial rodents (family Sciuridae) with different altitudinal ranges.. ... Hemoglobin function and allosteric regulation in semi-fossorial rodents (family Sciuridae) with different altitudinal ranges ... Hemoglobin function and allosteric regulation in semi-fossorial rodents (family Sciuridae) with different altitudinal ranges ... Hemoglobin function and allosteric regulation in semi-fossorial rodents (family Sciuridae) with different altitudinal ranges ...
  https://www.ncbi.nlm.nih.gov/pubmed/24172889
*  Novel ATP-cone-driven allosteric regulation of ribonucleotide reductase via the radical-generating subunit | eLife
Structural and functional characterization of an unanticipated mode of allosteric activity regulation in ribonucleotide ... This type of allosteric regulation has been shown to provide an evolutionarily dynamic process by which allosteric regulation ... Allosteric regulation of an enzyme is defined as regulation of activity by binding of an effector molecule to a different ... Allosteric regulation of RNRs affects both substrate specificity and overall activity. The specificity regulation has been ...
  https://elifesciences.org/articles/31529
*  Familial and Somatic BAP1 Mutations Inactivate ASXL1/2-Mediated Allosteric Regulation of BAP1 Deubiquitinase by Targeting...
Familial and Somatic BAP1 Mutations Inactivate ASXL1/2-Mediated Allosteric Regulation of BAP1 Deubiquitinase by Targeting ... Familial and Somatic BAP1 Mutations Inactivate ASXL1/2-Mediated Allosteric Regulation of BAP1 Deubiquitinase by Targeting ... Familial and Somatic BAP1 Mutations Inactivate ASXL1/2-Mediated Allosteric Regulation of BAP1 Deubiquitinase by Targeting ... Familial and Somatic BAP1 Mutations Inactivate ASXL1/2-Mediated Allosteric Regulation of BAP1 Deubiquitinase by Targeting ...
  http://cancerres.aacrjournals.org/content/early/2017/12/28/0008-5472.CAN-17-2876
*  Allosteric regulation of the adenosine triphosphate phosphoribosyltransferase from campylobacter jejuni
In the long form ATP-PRT histidine binds to the allosteric site at the regulatory domain, but the exact nature of the ... In chapter 4 a potential intramolecular communication pathway from the allosteric to the active site is probed by the ... ATP-PRT activity is modulated by two layers of regulation: active site inhibition by adenosine monophosphate, which reflects ... although this ligand is still able to bind at the allosteric site, which is consistent with the involvement of R216 in the ...
  https://ir.canterbury.ac.nz/handle/10092/10799
*  Allosteric Regulation of Glycogen Synthase - Asociación Española de Enfermos de Glucogenosis (AEEG)
Allosteric Regulation of Glycogen Synthase Controls Glycogen Synthesis in Muscle. SUMMARY. Glycogen synthase (GS), a key enzyme ... Our study provides genetic evidence that allosteric activation of GS is the primary mechanism by which insulin promotes muscle ... Here we identify a residue that plays an important role in the allosteric activation of GS by G6P. ... mainly due to the complex interplay between multiple phosphorylation sites and allosteric effectors. ...
  http://www.glucogenosis.org/2015/10/26/allosteric-regulation-of-glycogen-synthase/
*  L0710ap - committed step in a pathway Allosteric regulation(mechanism Binding of ATP to a non-substrate(allosteric site on the...
committed step in a pathway Allosteric regulation (mechanism) Binding of ATP to a non-substrate (allosteric) site on the enzyme ... committed step in a pathway Allosteric regulation (mechanism) Binding of ATP to a non-substrate (allosteric) site on the enzyme ... Regulation of Glycolysis Learning Objectives: List the points of regulation in glyco ... Net reaction rate is: Inhibited by ↑ATP Accelerated by ↑ADP Feedback regulation (principle) End products of biochemical ...
  https://www.coursehero.com/file/6123813/L0710ap/
*  Inserm - On the role of the difference in surface tensions involved in the allosteric regulation of NHE-1 induced by low to...
It is cooperatively activated by intracellular protons, and this allosteric regulation is modulated by the biophysical ... The purpose of this study was to develop the relationship between membrane surface tension, and the allosteric balance of a ... fluid phase endocytosis and the allosteric equilibrium constant of the transporter. We then used the experimental data ... published on the effects of osmotic pressure and membrane modification on the NHE-1 allosteric constant to fit these equations ...
  https://www.hal.inserm.fr/inserm-00871709
*  Definition of allosteric regulation - Chemistry Dictionary
Definition of allosteric regulation. 1) Allosteric regulation is the regulation of the activity of allosteric enzymes. (See ...
  http://www.chemistry-dictionary.com/definition/allosteric+regulation.php
*  Genetically encoded light-sensitive amino acids uncover allosteric regulation in neuronal receptors 理化学研究所 多細胞システム形成研究センター(
Genetically encoded light-sensitive amino acids uncover allosteric regulation in ... ホーム , セミナー・イベント , Genetically encoded light-sensitive amino acids uncover allosteric regulation in neuronal receptors ... Genetically encoded light-sensitive amino acids uncover allosteric regulation in neuronal receptors. ... Characterizations of light-induced allosteric modulations in the presence of inhibitors (Zn2+ and ifenprodil) and potentiators ...
  http://www.cdb.riken.jp/activities/2017/academic_events/seminar/0728_13792.html
*  Enzyme Inhibition - Types of Inhibition - Allosteric Regulation - TeachMePhysiology
Allosteric Inhibition. Allosteric enzymes display a sigmoidal curve in contrast to the hyperbolic curve displayed by Michaelis- ... How do allosteric inhibitors usually work? Bind to R state to maintain low affinity state of enzyme Bind to R state to maintain ... Allosteric enzymes have two states: a low affinity state dubbed the "T" state and the high affinity "R" state. Inhibitors work ... This is because most allosteric enzymes contain multiple sub-units which can affect each other when the substrate binds to the ...
  http://teachmephysiology.com/basics/enzyme-activity/enzyme-inhibition/
*  Receptor disulfide allosteric regulation of anthrax toxin action - Jianjun Sun
Receptor disulfide allosteric regulation of anthrax toxin action Sun, Jianjun University of Texas El Paso, El Paso, TX, United ... Receptor disulfide allosteric regulation of anthrax toxin action. Sun, Jianjun / University of Texas El Paso. $224,250. ... Receptor disulfide allosteric regulation of anthrax toxin action. Sun, Jianjun / University of Texas El Paso. $224,250. ... Receptor disulfide allosteric regulation of anthrax toxin action. Sun, Jianjun / University of Texas El Paso. $216,401. ...
  http://grantome.com/grant/NIH/SC1-GM095475-03
*  Postdoctoral Position - Allosteric Regulation in the KDM5 Family of Histone Demethylases | ISMAR
Postdoctoral Position - Allosteric Regulation in the KDM5 Family of Histone Demethylases. Submitted by mariabaias on Thu, 2015- ... Postdoctoral Position - Allosteric Regulation in the KDM5 Family of Histone Demethylases. *Postdoctoral Position Available in ... Postdoctoral Position - Allosteric Regulation in the KDM5 Family of Histone Demethylases. *Postdoctoral Position Available in ... The goal of this work is to expand our understanding of the mechanisms that underlie regulation of chromatin methylation and ...
  https://wws.weizmann.ac.il/ISMAR/positions/postdoctoral-position-allosteric-regulation-kdm5-family-histone-demethylases
*  Evidence for a Common Mechanism of SIRT1 Regulation by Allosteric Activators | Science
Evidence for a Common Mechanism of SIRT1 Regulation by Allosteric Activators. By Basil P. Hubbard, Ana P. Gomes, Han Dai, Jun ... Evidence for a Common Mechanism of SIRT1 Regulation by Allosteric Activators. By Basil P. Hubbard, Ana P. Gomes, Han Dai, Jun ... Evidence for a Common Mechanism of SIRT1 Regulation by Allosteric Activators Message Subject. (Your Name) has forwarded a page ... Thus, SIRT1 can be directly activated through an allosteric mechanism common to chemically diverse STACs. ...
  http://science.sciencemag.org/content/339/6124/1216.long
*  Molecular basis for allosteric specificity regulation in class Ia ribonucleotide reductase from Escherichia coli | eLife
Allosteric activity sites are shown with ATP modeled in cyan and dATP in red spheres. (E) Allosteric specificity regulation is ... First, allosteric activity regulation modulates the overall size of dNTP pools. ATP or dATP binding at an allosteric activity ... The second form of allosteric regulation is specificity regulation, which maintains the proper relative ratios of dNTPs in the ... Allosteric activity regulation is achieved by interconversion between an active α2β2 complex in the presence of the allosteric ...
  https://elifesciences.org/articles/07141
*  Lack of conventional oxygen-linked proton and anion binding sites does not impair allosteric regulation of oxygen binding in...
Lack of conventional oxygen-linked proton and anion binding sites does not impair allosteric regulation of oxygen binding in ...
  http://www.forskningsdatabasen.dk/catalog/243980667
*  Allosteric regulation of the partitioning of glucose-1-phosphate between glycogen and trehalose biosynthesis in Mycobacterium...
Allosteric regulation of the partitioning of glucose-1-phosphate between glycogen and trehalose biosynthesis in Mycobacterium ... None of the other two enzymes tested exhibited allosteric regulation. Conclusions: Results give information about how the ... The substrate specificity, kinetic parameters and allosteric regulation of each enzyme were determined. ADP-glucose ... Allosteric regulation of the partitioning of glucose-1-phosphate between glycogen and trehalose biosynthesis in Mycobacterium ...
  http://ri.conicet.gov.ar/handle/11336/39604
*  How Many Chromosomes Are Contained in a Human Male Gamete Cell? | Reference.com
What Is an Allosteric Regulation?. * Q: What Do You Call a Motor Neuron and All of the Skeletal Muscle Cells It Stimulates?. ...
  https://www.reference.com/science/many-chromosomes-contained-human-male-gamete-cell-8dfd2ddc668f1bff
*  biophysics | Philosophical Transactions of the Royal Society B: Biological Sciences
Markov models for the elucidation of allosteric regulation. Ushnish Sengupta, Birgit Strodel ... Folding cooperativity and allosteric function in the tandem-repeat protein class. Albert Perez-Riba, Marie Synakewicz, Laura S ... Ensemble allosteric model: energetic frustration within the intrinsically disordered glucocorticoid receptor. Jordan T. White, ... Shared dynamics of LeuT superfamily members and allosteric differentiation by structural irregularities and multimerization. ...
  http://rstb.royalsocietypublishing.org/collection/biophysics