*  The effect of moderate alcohol consumption on biomarkers of inflammation and hemostatic factors in postmenopausal women
Inflammation and hemostasis contribute to the etiology of cardiovascular disease. A study evaluated the effect of moderate alcohol consumption on biomarkers of inflammation and hemostasis in postmenopausal women. Previous studies by the same research group has demonstrated that moderate alcohol consumption (1-2 drinks/day) may decrease risk for cardiovascular disease because of an improved lipid profile. In addition to these beneficial changes, the alcohol-mediated reduction in risk may be through its effect on inflammation and hemostasis.. As part of a controlled diet study, 53 postmenopausal women each consumed a weight-maintaining diet plus 0, 15 and 30 g/day of alcohol for 8 weeks. The controlled diet contained 15%, 53% and 32% of energy from protein, carbohydrate and fat, respectively. Soluble intercellular adhesion molecule-1 decreased by 5% (P,0.05) with consumption of both 15 and 30 g of alcohol. Fibrinogen ...
  http://www.aim-digest.com/gateway/pages/women/articles/Inflammation.htm
*  Association of self-reported alcohol use and hospitalization for an alcohol-related cause in Scotland: a record-linkage study...
Investigates the extent to which self-reported alcohol consumption level in the Scottish population is associated with first-time hospital admission for an alcohol-related cause. Design Observational record-linkage study. A total of 23 183 respondents aged 16 and over who participated in the 1995, 1998 and 2003 Scottish Health Surveys, followed-up via record-linkage from interview date until 30 September 2005. Measurements Rate of first-time hospital admission with at least one alcohol-related diagnosis. Cox proportional hazards regression analysis was applied to estimate the relative risk of first-time hospitalization with an alcohol-related condition associated with usual alcohol consumption level (1-7, 8-14, 15-21, 22-35, 36-49, 50+ units/week and ex-drinker, compared with ,1 unit per week). Findings Of the SHS participants, 527 were hospitalized for an alcohol-related cause during 135 313 person-years of ...
  http://strathprints.strath.ac.uk/13385/
*  Adolescent alcohol consumption: Biomarkers PEth and FAEE in relation to interview and questionnaire data
Objective: The aim of this study was to investigate the congruence of biomarkers, questionnaires, and interviews as instruments to assess adolescent alcohol consumption. Method: The methodology used was a cross-sectional study with a randomized sample. Four different methods were used to estimate high adolescent alcohol consumption. The concordance of the results was investigated. Surveys were performed, and biological specimens were collected at all schools in the county of Västmanland, Sweden, in 2001. Eighty-one boys and 119 girls from a population of 16- and 19-year-old adolescents were randomly selected from quartiles of volunteers representing various degrees of psychosocial risk behaviors. Using a questionnaire (for a 1-hour session) and in-depth interviews, subjects were assessed regarding their alcohol-use habits. Blood and hair samples were analyzed for phosphatidylethanol (PEth) and fatty acid ethyl esters (FAEEs), respectively. Results: High ...
  http://liu.diva-portal.org/smash/record.jsf?pid=diva2:286339
*  New Study Confirms Possible Benefits of Moderate Alcohol Consumption - General News - News | DISCUS
Washington, DC - Moderate alcohol consumption is associated with a reduced risk of cardiovascular disease and mortality from all-causes, according to a new, large study of over 333,000 U.S. adults published yesterday in the Journal of the American College of Cardiology. The study findings did not differentiate between beer, wine and spirits. The study concluded that moderate alcohol consumption was associated with a 21 percent and 34 percent decreased risk of cardiovascular disease mortality and a 13 percent and 25 percent decreased risk of all-cause mortality, respectively, in both men and women. Similar findings were observed for light drinking among men and women.. The researchers found, "the protective effect of light-to-moderate alcohol consumption was more pronounced in women, middle-aged and older populations.". The researchers noted that previous studies showed that "all alcoholic drinks at moderate level were ...
  http://www.discus.org/new-study-confirms-possible-benefits-of-moderate-alcohol-consumption/?pg=5&
*  Abstract P297: Alcohol Consumption and Cardiac Biomarkers | Circulation
Background: Excess alcohol consumption can lead to myocardial dysfunction. However, whether novel cardiac biomarkers tests can detect subclinical myocardial damage and wall stress in asymptomatic populations exposed to alcohol is currently unknown.. Objective: To characterize the association of alcohol consumption with subclinical myocardial damage, as assessed by a novel highly sensitive assay for cardiac troponin T (hs-cTnT) and wall stress, as assessed by N-terminal pro-brain natriuretic peptide (NT-proBNP).. Methods: Using data from the community-based ARIC Study we examined the cross-sectional association of categories of self-reported alcohol consumption with cardiac biomarkers among 10,381 individuals without cardiovascular disease (1990-92). We also examined the prospective association of alcohol consumption with 6-year change in cardiac biomarkers in a subset of participants (n=8,972 for hs-cTnT and n=9,060 for ...
  http://circ.ahajournals.org/content/131/Suppl_1/AP297
*  Effects of study design and allocation on self-reported alcohol consumption: randomized trial | Trials | Full Text
There were no differences between the groups ('cohort' versus 'control' and 'intervention'; or 'control' versus 'intervention') in drinking one month after baseline as a function of what participants were given to believe about the study. Accordingly, neither of the null hypotheses can be rejected. There was a large difference in the percentage of the 'intervention' group who clicked on the alcohol information, and in the amount of time spent viewing that information, relative to the other groups, suggesting that the 'intervention' group treated the alcohol information in the way intended, as an intervention. There was no difference between the 'cohort' and 'control' groups in accessing of the alcohol information, suggesting the possibility of failure in the experimental manipulation, particularly as this measure was primarily designed as a manipulation check and was not specified a priori as an outcome measure.. Strengths of the study ...
  https://trialsjournal.biomedcentral.com/articles/10.1186/s13063-015-0642-0
*  Parenting influences on adolescent alcohol use - 3. Alcohol: Age of initiation, levels of use, and risky use | Australian...
Before proceeding with a discussion of parenting influences, it is necessary to set the scene by discussing rates and levels of alcohol use among Australian adolescents. This section provides an overview of information about: the age at which Australian adolescents commence drinking; levels of adolescent alcohol consumption, distinguishing between 'moderate' and 'risky' levels of use; the risks associated with alcohol consumption; adolescents' views of alcohol and their reasons for drinking; their source of access to alcohol; and the settings in which adolescent alcohol use takes place.
  https://aifs.gov.au/publications/parenting-influences-adolescent-alcohol-use/3-alcohol-age-initiation-levels-use-and
*  Integrated Stepped Care for Unhealthy Alcohol Use in HIV - Full Text View - ClinicalTrials.gov
Unhealthy alcohol use threatens the health benefits seen with antiretroviral therapy (ART) for HIV-infected (HIV+) patients. Although research has demonstrated the efficacy of brief interventions, motivational counseling, and medications to treat unhealthy alcohol use in HIV uninfected patients, there is limited research or use of these treatments in HIV+ patients. We have demonstrated that integrated treatment of addiction in HIV clinics is feasible. Stepped care algorithms can facilitate the evaluation of varying intensities of treatments for unhealthy alcohol use. The proposed study will compare onsite Integrated Stepped Care treatment (ISC) to treatment as usual (TAU) in three, linked, 6-month randomized clinical trials in 642 HIV+ patients with unhealthy alcohol use. Screened patients are randomized to ISC or TAU after determining that they meet criteria for either 1) at-risk drinking, 2) alcohol abuse ...
  https://clinicaltrials.gov/show/NCT01410123?order=120
*  Integrated Stepped Care for Unhealthy Alcohol Use in HIV - Full Text View - ClinicalTrials.gov
Unhealthy alcohol use threatens the health benefits seen with antiretroviral therapy (ART) for HIV-infected (HIV+) patients. Although research has demonstrated the efficacy of brief interventions, motivational counseling, and medications to treat unhealthy alcohol use in HIV uninfected patients, there is limited research or use of these treatments in HIV+ patients. We have demonstrated that integrated treatment of addiction in HIV clinics is feasible. Stepped care algorithms can facilitate the evaluation of varying intensities of treatments for unhealthy alcohol use. The proposed study will compare onsite Integrated Stepped Care treatment (ISC) to treatment as usual (TAU) in three, linked, 6-month randomized clinical trials in 642 HIV+ patients with unhealthy alcohol use. Screened patients are randomized to ISC or TAU after determining that they meet criteria for either 1) at-risk drinking, 2) alcohol abuse ...
  https://clinicaltrials.gov/show/NCT01410123?order=121
*  Alcohol Use and Risky Sexual Behaviors Among HIV Infected Subjects in Kampala Uganda - Full Text View - ClinicalTrials.gov
Background: Approximately 6.4% of Ugandans are living with HIV, that is acquired and transmitted mainly through sexual intercourse between an HIV infected and uninfected person. Uganda is ranked among 28 top per capita alcohol consumers in the world and second in Africa. in the general population, Alcohol consumption is associated with increased sexual transmission risks for HIV. Data on alcohol consumption and its impact on sexual behaviors and HIV disease progression among HIV infected persons, the persons able to transmit HIV are lacking in this setting.. Objectives: To estimate the prevalence of alcohol consumption among HIV infected persons, assess associations between alcohol and CD4 cell count as well as evaluate the effect of alcohol motivational intervention counseling on alcohol consumption and the subsequent practice of risky sexual behaviors, among HIV infected persons.. ...
  https://clinicaltrials.gov/ct2/show/NCT01802736?term=%22+February+06%2C++2013%22%3A%22+March+08%2C++2013%22%5BFIRST-RECEIVED-DATE%5DAND+HIV%5BCONDITION%5D&rank=16
*  Genetics, Pharmacokinetics, and Neurobiology of Adolescent Alcohol Use
Complex behaviors such as the initiation and use of alcohol result from an intricate interplay between genes and environment. Genes shape physiological and behavioral responses to alcohol that can influence the likelihood that a young person will begin using alcohol and that he or she will progress to problem drinking. Youthful alcohol use also can have an impact on unfolding developmental patterns, and for some, early use becomes the entry point for pathways that lead to problems with alcohol. This article first describes research on genes that may be involved in the development of alcohol problems and how genetic factors may contribute to adolescent alcohol use. It then examines how the changes that occur during adolescent development-in alcohol metabolism, in the brain, and in the endocrine and stress response systems-may affect how a young person ...
  http://connection.ebscohost.com/c/articles/19363492/genetics-pharmacokinetics-neurobiology-adolescent-alcohol-use
*  Relationship Between Alcohol and Blood Pressure | Actforlibraries.org
Alcohol is one of the main causes of high blood pressure. A doctor recommends cutting back on alcohol when a patient is diagnosed with high blood pressure. Alcohol affects the body in different ways. For example, steady alcohol consumption over a long period permanently changes the brain by reducing the amount of brain tissue. Steady alcohol consumption also deprives the heart of essential nutrients. This weakens the heart muscles and hinders its ability to pump blood. This increases blood pressure and causes heart attacks and strokes. Alcohol also affects the liver, skin, lungs and bones among other parts of the body. In addition, alcohol contains sugar and other carbohydrates that increase weight. Weight gain is another cause of high blood pressure.. How Alcohol Increases Blood Pressure There is no concrete proof as to how alcohol affects blood pressure. ...
  http://www.actforlibraries.org/alcohol-and-blood-pressure/
*  Health News Report: Moderate Alcohol Consumption - Mortality Benefits
Most of the previous studies assessed alcohol intake at baseline; however, in this study researchers collected detailed information seven times over 40 years. "Consumption patterns usually change during life," Streppel said. "This enabled us to study the effects of long-term alcohol intake on mortality." Researchers found that the number of alcohol users nearly doubled from 45 percent in 1960 to 85 percent in the 2000 survey. Average alcohol consumption rose and then fell at various points during the study. Users' consumption was eight grams a day in 1960, then survivors' consumption was 18 grams a day in 1985, dropping to 13 grams per day in 2000. The percentage of wine users increased during follow-up from 2 percent in 1960 to more than 40 percent among the survivors in 2000. "One can speculate that a protective effect of light alcohol intake could be due to an increase in high-density lipoprotein (HDL) cholesterol, or to ...
  http://healthnewsreport.blogspot.com/2014/11/moderate-alcohol-consumption-mortality.html
*  Alcohol consumption and polymorphisms of cytochromes P4502E1 are high risk... ( Heavier alcohol consumption increase...)
Health, ...Heavier alcohol consumption increases the risk of ESCC. There are syne...This study performed by a team led by Dr. Yan-Mei Guo is described i...ESCC is the seventh leading cause of cancer deaths worldwide. Epidemio...In the view of the authors no clear explanation has to date existed...,Alcohol,consumption,and,polymorphisms,of,cytochromes,P4502E1,are,high,risks,for,ESCC,medicine,medical news today,latest medical news,medical newsletters,current medical news,latest medicine news
  http://www.bio-medicine.org/medicine-news-1/Alcohol-consumption-and-polymorphisms-of-cytochromes-P4502E1-are-high-risks-for-ESCC-14278-1/
*  Influence of sex, age, body mass index, and smoking on alcohol intake and mortality | The BMJ
Many have questioned the validity of self reported alcohol intake, but until now one of the available methods to obtain the information (sales reports, collateral information, etc) has proved to be more valid.20 We made no attempt to validate the subjects' reported histories. Trained staff went through the histories as reported in the questionnaire with the subject. Subjects had no reason to deny their alcohol intake, as may be the case, for example, in data collected for insurance purposes. Still, the alcohol intake may have been underreported. If the underreporting was equal at all levels the observed risk function would be moved to the left of the true risk function, which means that the present study would overestimate the risk of dying from given reported levels of alcohol intake in the groups with higher alcohol intake, while the nadir, also moving to the left, would be at a lower intake. If the underreporting was ...
  http://www.bmj.com/content/308/6924/302.long
*  Alcohol consumption, early onset drinking and health-related consequences in adolescents presenting at Emergency Departments in...
Globally, alcohol use is the leading cause of ill health and life years lost in adolescents, although its clinical impact is often overlooked, particularly in England where most research is based in schools. This study aims to examine the prevalence of alcohol consumption and the association between alcohol consumption and age of onset with health and social consequences among adolescents presenting to emergency departments (EDs). Methods Consecutive attenders (n = 5,576) aged 10-17 years at 10 EDs were included. Information was collected on general health and functioning, quality of life, alcohol use, and alcohol-related health and social consequences. Results Nearly 40% of adolescents reported the consumption of alcohol that was more than a sip in their lifetime. Age of the first alcohol consumption before the age of 15 years was associated with tobacco use (p , .001), lower quality of ...
  http://epubs.surrey.ac.uk/813342/
*  Review: a mean alcohol intake of 30 g/day is associated with benefits for some biological markers of coronary artery disease |...
The cardiovascular benefits of consuming alcohol have been of particular interest during the last decade. Studies included in this meta-analysis by Rimm et al for effects on lipoproteins and other biological markers had relatively small sample sizes, involved predominantly younger (,50 y of age) and male (82% of total sample) participants, and studied the effects of alcohol consumption over a short duration (range 1 day to 3 mo). Meta-analytic methods enable pooling of studies to enhance the sample size and the effect of the intervention.. In everyday terms, "moderate alcohol consumption" represents approximately 30 g of alcohol per day (eg, 24 oz or 720 ml of regular beer; 10 oz or 300 ml of table wine; 2 oz or 60 ml of spirits).1-2 As the authors indicate, there is "a decreased first pass metabolism of alcohol among women that may accentuate... (its) effects". In fact, recommendations exist that women and lighter weight ...
  http://ebn.bmj.com/content/3/3/89?frame=sidebar
*  China Digital Wine Alcohol Tester Breath Alcohol Tester Alcohol Breathalyzer Sensor - China Digital Alcohol Tester Alcohol...
China Digital Wine Alcohol Tester Breath Alcohol Tester Alcohol Breathalyzer Sensor, Find details about China Digital Alcohol Tester Alcohol Breath Tester, Breathalyzer from Digital Wine Alcohol Tester Breath Alcohol Tester Alcohol Breathalyzer Sensor - Shenzhen Ipopman Technology Limited
  http://cnipopman.en.made-in-china.com/product/fNgmelHYqnkL/China-Digital-Wine-Alcohol-Tester-Breath-Alcohol-Tester-Alcohol-Breathalyzer-Sensor.html
*  Brief Therapy Intervention for Heavy/Hazardous Drinking in HIV-Positive Women - Full Text View - ClinicalTrials.gov
Heavy alcohol use negatively impacts HIV/AIDS in several important ways. It increases HIV-risk behaviors, impairs the immune system and accelerates HIV disease progression. Heavy alcohol use also interferes with HIV care compliance, including appointment attendance and medication adherence.. Women are particularly important targets for alcohol use interventions. The threshold for harmful alcohol effects is strikingly low in women, with two drinks per day placing women at risk for negative health consequences. Heavy/hazardous alcohol use is less likely to be detected in women receiving health services. Women may be less likely to seek and or engage in alcohol treatment services, making nontraditional care settings particularly important for reaching this population.. This proposal tests the utility of a brief alcohol intervention for HIV+ women delivered in a medical setting. Hazardous/binge ...
  https://clinicaltrials.gov/ct2/show/study/NCT00127231?view=results
*  Brief Therapy Intervention for Heavy/Hazardous Drinking in HIV-Positive Women - Full Text View - ClinicalTrials.gov
Heavy alcohol use negatively impacts HIV/AIDS in several important ways. It increases HIV-risk behaviors, impairs the immune system and accelerates HIV disease progression. Heavy alcohol use also interferes with HIV care compliance, including appointment attendance and medication adherence.. Women are particularly important targets for alcohol use interventions. The threshold for harmful alcohol effects is strikingly low in women, with two drinks per day placing women at risk for negative health consequences. Heavy/hazardous alcohol use is less likely to be detected in women receiving health services. Women may be less likely to seek and or engage in alcohol treatment services, making nontraditional care settings particularly important for reaching this population.. This proposal tests the utility of a brief alcohol intervention for HIV+ women delivered in a medical setting. Hazardous/binge ...
  https://clinicaltrials.gov/show/NCT00127231?order=141
*  Brief Therapy Intervention for Heavy/Hazardous Drinking in HIV-Positive Women - Full Text View - ClinicalTrials.gov
Heavy alcohol use negatively impacts HIV/AIDS in several important ways. It increases HIV-risk behaviors, impairs the immune system and accelerates HIV disease progression. Heavy alcohol use also interferes with HIV care compliance, including appointment attendance and medication adherence.. Women are particularly important targets for alcohol use interventions. The threshold for harmful alcohol effects is strikingly low in women, with two drinks per day placing women at risk for negative health consequences. Heavy/hazardous alcohol use is less likely to be detected in women receiving health services. Women may be less likely to seek and or engage in alcohol treatment services, making nontraditional care settings particularly important for reaching this population.. This proposal tests the utility of a brief alcohol intervention for HIV+ women delivered in a medical setting. Hazardous/binge ...
  https://clinicaltrials.gov/show/NCT00127231?order=205
*  Brief Therapy Intervention for Heavy/Hazardous Drinking in HIV-Positive Women - Full Text View - ClinicalTrials.gov
Heavy alcohol use negatively impacts HIV/AIDS in several important ways. It increases HIV-risk behaviors, impairs the immune system and accelerates HIV disease progression. Heavy alcohol use also interferes with HIV care compliance, including appointment attendance and medication adherence.. Women are particularly important targets for alcohol use interventions. The threshold for harmful alcohol effects is strikingly low in women, with two drinks per day placing women at risk for negative health consequences. Heavy/hazardous alcohol use is less likely to be detected in women receiving health services. Women may be less likely to seek and or engage in alcohol treatment services, making nontraditional care settings particularly important for reaching this population.. This proposal tests the utility of a brief alcohol intervention for HIV+ women delivered in a medical setting. Hazardous/binge ...
  https://clinicaltrials.gov/show/NCT00127231?order=36
*  Saúde Pública - Alcohol, diabetes, and public health in the Americas Alcohol, diabetes, and public health in the Americas
The interaction between diabetes mellitus and alcohol consumption is complex. While regular light-tomoderate drinking may decrease the risk for diabetes, heavy drinking increases this risk (1, 2). Moreover, alcohol consumption, especially "binge" drinking (heavy episodic consumption), can worsen the course of the disease and influence its outcomes via a number of mechanisms. Recent meta-analyses, systematic reviews, and primary studies (1, 2) illustrate the multiple ways alcohol consumption can affect diabetes, and provide the basis for integrating alcohol control measures into the public health approach to diabetes prevention and management within the context of the World Health Organization (WHO) global strategy to reduce the harmful use of alcohol (3). This article describes the association between alcohol use and diabetes within the context of new ...
  https://scielosp.org/scielo.php?script=sci_arttext&pid=S1020-49892012000800010&lng=pt&nrm=iso&tlng=pt
*  Intrapersonal and environmental factors associated with Chinese youth alcohol use experimentation and binge drinking behaviors ...
This study investigated intrapersonal and environmental determinants of alcohol use in a Chinese youth population to explore the role that such determinants have on alcohol use behaviors. This study analyzed which determinants functioned as risk and protective factors for the transition to increased alcohol use; and which variables moderated the impact of other variables in their relationship to alcohol use onset and progression. Longitudinal data from the China Seven Cities Study (CSCS), a health behavior study in seven of China 's largest cities, were employed to study these matters. Data was analyzed from 14,434 7th, 8th, 10th, and 11th grade middle and high school students and their parents/guardians for this study. This study identified important determinants of Chinese youth drinking onset and transition behaviors. Junk food use, smoking behavior, and allowance were incrementally associated with increasing levels of ...
  http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll127/id/198550/rec/122
*  Alcohol: Science, Policy and Public Health - Oxford Scholarship
Alcohol has always been an issue in public health but it is currently assuming increasing importance as a cause of disease and premature death worldwide. This book provides an interdisciplinary source of information that links together the usually separate fields of science, policy, and public health. This volume highlights the importance of bringing scientific knowledge to bear in order to strengthen and develop alcohol public policy. The book looks at the historical evolution of alcohol consumption in society, key early studies of alcohol and disease, and the cultural and social aspects of alcohol consumption. It then goes on to cover the chemistry and biology of alcohol, patterns of consumption, gender and age-related issues, alcohol and injury, alcohol and cancer and non-malignant disease, and various current therapeutic aspects. The book concludes with a section on ...
  http://www.oxfordscholarship.com/view/10.1093/acprof:oso/9780199655786.001.0001/acprof-9780199655786?rskey=jodZRN&result=6