Multiple Brain Markers are Linked to Age-Related Variation in Cognition
Clinically normal older humans aged 65-90 from the Harvard Aging Brain Study (N = 186) were characterized on a priori magnetic ... aging; amyloid, executive function, memory, white matter National Category Neurosciences Identifiers. URN: urn:nbn:se:umu:diva- ... Of the age-related variance in cognition, 70-80% was accounted for by combining all brain markers (but only ∼20% of total ... Age-related alterations in brain structure and function have been challenging to link to cognition due to potential overlapping ...http://umu.diva-portal.org/smash/record.jsf?pid=diva2:808295
JCI - Aging-associated inflammation promotes selection for adaptive oncogenic events in B cell progenitors
Proinflammatory cytokines, aging, and age-related diseases. J Am Med Dir Assoc. 2013;14(12):877-882.. View this article via: ... In senescence, age-associated B cells secrete TNFα and inhibit survival of B-cell precursors. Aging Cell. 2013;12(2):303-311. ... Miller JP, Allman D. Linking age-related defects in B lymphopoiesis to the aging of hematopoietic stem cells. Semin Immunol. ... BALB/c and C57BL/6 mice of different ages were purchased from the National Institute of Aging (NIA) or the National Cancer ...https://jci.org/articles/view/83024
"Polymorphism of age-dependent changes in the production of a thf helpe" by T Matsuzawa and B Cinader
Matsuzawa, T and Cinader, B, "Polymorphism of age-dependent changes in the production of a thf helper factor." (1982). Subject ... Polymorphism of age-dependent changes in the production of a thf helper factor. ...https://mouseion.jax.org/ssbb1982/2609/
RFA-AG-18-018: Development of Valid Reliable Markers of Aging-Related Biologic Mechanisms for Human Studies (U01)
Development of Valid Reliable Markers of Aging-Related Biologic Mechanisms for Human Studies (U01) RFA-AG-18-018. NIA ... It may be possible to prevent or ameliorate multiple adverse age-related outcomes by slowing or reversing aging changes though ... Use data from linked cohorts spanning different age ranges to examine relationships of markers to aging changes from early life ... individuals of differing ages and within the same age cohort, and assess their relationships in humans to in vivo functions ...https://grants.nih.gov/grants/guide/rfa-files/RFA-AG-18-018.html
Heightened self-reactivity associated with selective survival, but not expansion, of naïve virus-specific CD8+ T cells in aged...
We show differential onset of decline for several IAV-specific CD8+ T-cell populations with advanced age that parallel age- ... In advanced age, decreased CD8+ cytotoxic T-lymphocyte (CTL) responses to novel pathogens and cancer is paralleled by a decline ... Furthermore, naïve CD8+ T cells expressing high levels of CD44 accumulate with age, but it is unknown whether this accumulation ... Heightened self-reactivity associated with selective survival, but not expansion, of naïve virus-specific CD8+ T cells in aged ...http://prism.edu.au/publications/502/
American Aging Association - Home
to Delay Aging. AGE 47th Annual Meeting. June 27-July 1, 2018. Philadelphia. (with the 2018 Nathan Shock Centers Summit). ... The American Aging Association is a group of experts dedicated to understanding the basic mechanisms of aging to enable methods ... Sergei Doulatov, PhD, Assistant Professor, University of Washington: The role of autophagy in hematopoietic stem cell aging. ... AGE would like to thank Duncan Palmatier for helping obtain the trademark GeroScience. ...https://www.americanagingassociation.org/
Investigation of Transcriptome Dysregulation in Brain Ageing | babs
RNA sequencing reveals pronounced changes in the noncoding transcriptome of aging synaptosomes', Neurobiol Aging, 56:67-77. ... Human brain ageing is characterised by decreasing cognitive function of various severity affecting 60% of aged population. ... Diminished cognitive function with increased age is likely a manifestation of dysregulated synaptic function and ineffective ...https://www.babs.unsw.edu.au/research/investigation-transcriptome-dysregulation-brain-ageing
Age-related effects of the neuromodulator d-serine on neurotransmission and synaptic potentiation in the CA1 hippocampal area...
... but with a larger magnitude in aged rats, thus preventing the age-related decrease in NMDAr activation. d-serine also increased ... Circuit-specific changes in d-serine-dependent activation of the N-methyl-D-aspartate receptor in the aging hippocampus, AGE, ... Age-related effects of the neuromodulator d-serine on neurotransmission and synaptic potentiation in the CA1 hippocampal area ... J.-M. Billard, Serine racemase as a prime target for age-related memory deficits, European Journal of Neuroscience, 2013, 37, ...http://onlinelibrary.wiley.com/doi/10.1111/j.1471-4159.2006.03944.x/abstract
Elderly at the bath: Medical Supplies for the elderly
Medical supplies for the elderly are especially helpful for allowing aged individuals to perform satisfactorily in the bathroom ... Medical supplies for the elderly are especially helpful for allowing aged individuals to perform satisfactorily in the bathroom ...http://www.discountmedicalsupplies.com/doctors/caregiver/elderly-bath-medical-supplies-elderly
The Aging Brain: Why We Forget and What Might Help - Juvenon.com
aging ala alc anti-aging avocado basil blues brain brain health cheese cilantro diabetes diet eating energy exercise fat food ... as we age. So, what's happening to us? Let's take a closer look at some of the scientific knowledge about the aging brain and ... This Research Update column highlights articles related to recent scientific inquiry into the process of human aging. It is not ... on levels of NMDAR in aged mice. The investigators suspected this antioxidant is an important piece of the age-associated ...http://juvenon.com/the-aging-brain-why-we-forget-and-what-might-help-611/
IJMS | Free Full-Text | Oxidative Stress and Epigenetic Regulation in Ageing and Age-Related Diseases | HTML
To understand the process leading to age-associated alterations is, therefore, of the highest relevance for the development of ... might orchestrate the progressive loss of control over biological homeostasis and the functional impairment typical of aged ... new treatments for age-associated diseases, such as cancer, diabetes, Alzheimer and cardiovascular accidents. Mechanistically, ... Stadtman, E.R. Protein oxidation in aging and age-related diseases. Ann. N. Y. Acad. Sci 2001, 928, 22-38. [Google Scholar] ...http://mdpi.com/1422-0067/14/9/17643/htm
Reading and solving arithmetic problems improves cognitive functions of normal aged people: a randomized controlled study |...
People generally believe the so-called mental-exercise hypothesis, that is, the age-related decline in cognitive fun ... The relationship between mental exercise and mental aging is a controversial issue. ... Salthouse TA (2006) Mental exercise and mental aging. Perspect Psychol Sci 1:68-87CrossRefGoogle Scholar ... Here, we introduce a new cognitive intervention program for normal aged people, the concept of which is derived from the ...https://link.springer.com/article/10.1007%2Fs11357-007-9044-x
Age-related decrease in proteasome expression contributes to defective nuclear factor-κB activation during hepatic ischemia...
Age-related changes in the 20S and 26S proteasome activities in the liver of male F344 rats. Mech Ageing Dev 1998; 102: 55-66. ... Alteration of rat liver 20S proteasome activities by age and food restriction. J Gerontol A Biol Sci Med Sci 1996; 51: B316- ... Age-dependent responses to hepatic ischemia/reperfusion injury. Shock 2005; 24: 421-427.. *CrossRef, ... Age-related decrease in proteasome expression contributes to defective nuclear factor-κB activation during hepatic ischemia/ ...http://onlinelibrary.wiley.com/doi/10.1002/hep.22840/references
The normal age variation in left ventricular parameters | Open-i
The normal age variation in left ventricular parameters in males (left) and females (right). Solid lines represent rational ... Results: Age and gender specific normal ranges for LV volumes, mass and function are presented from the second through the ... Results: Age and gender specific normal ranges for LV volumes, mass and function are presented from the second through the ... Conclusion: LV volumes, mass and function vary over a broad age range in healthy individuals. LV volumes and mass both rise in ...https://openi.nlm.nih.gov/detailedresult.php?img=PMC2657902_1471-2342-9-2-2&req=4
Age related change in the supraspinatus tendon - Oxford Clinical Trials Research Unit
Findings that something in your blood can influence the way you think could lead to new treatments for age-associated declines...
For largely unknown reasons, the hippocampus is especially vulnerable to normal aging, said Wyss-Coray. "With advancing age, ... Potential anti-aging component of cord blood refreshes minds of old mice on April 20, 2017 at 7:14 am The mice also got better ... Could Young Blood Boost Aging Brains? on April 20, 2017 at 2:21 am That led to a critical question: What is it about umbilical ... A protein from umbilical cords could revitalize memory in an aging brain on April 19, 2017 at 5:00 pm They also isolated the ...http://www.innovationtoronto.com/2017/04/findings-that-something-in-your-blood-can-influence-the-way-you-think-could-lead-to-new-treatments-for-age-associated-declines-in-mental-ability/
Frontiers | Environmental enrichment strengthens corticocortical interactions and reduces amyloid-β oligomers in aged mice |...
... in aged wild-type mice. We analyzed the functional consequences of EE on aged brain physiology by performing in vivo local ... in aged wild-type mice. We analyzed the functional consequences of EE on aged brain physiology by performing in vivo local ... Considering the high social impact of the decline in brain performance associated to aging, there is an urgent need to better ... Considering the high social impact of the decline in brain performance associated to aging, there is an urgent need to better ...https://www.frontiersin.org/articles/10.3389/fnagi.2014.00001/full
National Institute on Aging
on health & aging & Alzheimer's. Get research news & funding opportunities from the National Institute on Aging at NIH. ... Global Aging. Find information on research into global trends in aging and aging-related diseases. ... Aging Research Advances. Since its founding in 1974, NIA research has changed the way America understands aging. ... Baltimore Longitudinal Study of Aging. The Baltimore Longitudinal Study of Aging is America's longest-running scientific study ...https://www.nia.nih.gov/
Age of Autism Awards 2010: Dr. Paul Offit, Denialist of the Decade - AGE OF AUTISM
... after which an age-related decline dominates in the elderly. Based on a realistic age-structured model, we compare differences ... Posted by Age of Autism on December 29, 2010 at 05:45 AM in Abdulkadir Khalif, Anne Dachel, Cathy Jameson, Current Affairs, Dan ... Age of Autism Awards 2010: Dr. Paul Offit, Denialist of the Decade By Dan Olmsted ... He should wear his black hooded cloak and carry his sickle when he recieves this award for 'Monster of the Decade' from Age of ...http://www.ageofautism.com/2010/12/age-of-autism-awards-2010-dr-paul-offit-denialist-of-the-decade.html
Understanding of gravity in the Middle Ages | Physics Forums - The Fusion of Science and Community
I would say yes if you are talking about a temporal frame of reference, i.e. Middle Ages vs. Information Age. ... Similar Discussions: Understanding of gravity in the Middle Ages * Middle of gravity (Replies: 5) ... I have read that in the Middle Ages people believed that angels pushed the Moon in its orbit, the angelic push presumably being ... What else did people in the Middle Ages know about gravity? Did they, for example, know that the same force which was ...https://www.physicsforums.com/threads/understanding-of-gravity-in-the-middle-ages.936516/
Media Use in School-Aged Children and Adolescents | From the American Academy of Pediatrics | Pediatrics
Pathological video-game use among youth ages 8 to 18: a national study. Psychol Sci. 2009;20(5):594-602pmid:19476590. ... It is estimated that ∼12% of youth aged 10 to 19 years have ever sent a sexual photo to someone else.44 The Internet also has ... A recent study found that TV hours among school-aged children have decreased in the past decade for children younger than 8 ... This policy statement focuses on children and adolescents 5 through 18 years of age. Research suggests both benefits and risks ...http://pediatrics.aappublications.org/content/early/2016/10/19/peds.2016-2592
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In a study conducted to understand the effect of aging on carbohydrates digestion and absorption, both older and younger age ... manometric studies of the colon in the elderly fail to identify any age-related decrease in the motility. In the aged colon, ... but not in the younger age groups (3) . Finally, the brush border peptidases seem also to remain intact with older age, and ... it is worth mentioning that serum insulin levels increase with age, but the sensitivity to insulin diminishes with age (1) . ...http://www.angelfire.com/ky/IBMS/aginggi.html
Rejuvenation (aging) - Wikipedia
Ageless Aging brain American Academy of Anti-Aging Medicine Biogerontology Biological immortality DNA repair DNA damage theory ... Life extension strategies often study the causes of aging and try to oppose those causes in order to slow aging. Rejuvenation ... de Grey, Aubrey; Rae, Michael (September 2007). Ending Aging: The Rejuvenation Breakthroughs that Could Reverse Human Aging in ... was applied as a robust method of decelerating aging and the development of age-related diseases. The biomedical gerontologist ...https://en.wikipedia.org/wiki/Rejuvenation_(aging)
Aging Rockers - latimes
Concerning Robert Hilburn's June 25 article, 'Never Too Old to Rock':The Who? My gosh--they died years ago, yet they continue to plague us.They stopped doing anything worthwhile a long time ago.http://articles.latimes.com/1989-07-09/entertainment/ca-5015_1_david-bowie-aging-rockers-spare
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