*  The Role of Sympatho-vagal Balance on Different Limbs of Pain Perception in Healthy Subjects - Full Text View - ClinicalTrials...
Adrenergic alpha-Antagonists. Adrenergic Antagonists. Adrenergic Agents. Neurotransmitter Agents. Molecular Mechanisms of ... Every subject will be invited to 2 separate sessions. At least 24 hours will apart the two sessions. The test in each session ...
  https://clinicaltrials.gov/ct2/show/NCT01621620?recr=Open&cond=%22Pain+Perception%22&rank=10
*  Studies of Opioid Seeking Behavior: Yohimbine and Hydrocortisone Effects - Full Text View - ClinicalTrials.gov
Adrenergic alpha-Antagonists. Adrenergic Antagonists. Adrenergic Agents. Neurotransmitter Agents. Molecular Mechanisms of ... Phase 2: Participants will then live on an inpatient research unit (located in Detroit Michigan) for at least 16 consecutive ...
  https://clinicaltrials.gov/ct2/show/NCT01536925?recr=Open&cond=%22Opioid-Related+Disorders%22&rank=3
*  A Comparison of Study Drug With Placebo and Haloperidol in Patients With Schizophrenia - Full Text View - ClinicalTrials.gov
Adrenergic alpha-Antagonists. Adrenergic Antagonists. Adrenergic Agents. Serotonin 5-HT2 Receptor Antagonists. Serotonin ... Dopamine Antagonists. Dopamine Agents. Neurotransmitter Agents. Molecular Mechanisms of Pharmacological Action. Anti-Dyskinesia ...
  https://clinicaltrials.gov/ct2/show/NCT00044044
*  Lurasidone HCI - A 6-week Phase 3 Study of Patients With Bipolar I Depression - Full Text View - ClinicalTrials.gov
Adrenergic alpha-Antagonists. Adrenergic Antagonists. Adrenergic Agents. Neurotransmitter Agents. Molecular Mechanisms of ... Serotonin 5-HT2 Receptor Antagonists. Serotonin Antagonists. Serotonin Agents. Dopamine D2 Receptor Antagonists. Dopamine ...
  https://clinicaltrials.gov/ct2/show/NCT01284517
*  Major Depressive Disorder With Mixed Features - Extension - Full Text View - ClinicalTrials.gov
Adrenergic alpha-Antagonists. Adrenergic Antagonists. Adrenergic Agents. Neurotransmitter Agents. Molecular Mechanisms of ... Serotonin 5-HT2 Receptor Antagonists. Serotonin Antagonists. Serotonin Agents. Dopamine D2 Receptor Antagonists. Dopamine ...
  https://clinicaltrials.gov/ct2/show/NCT01423253
*  PEARL Schizophrenia Maintenance - Full Text View - ClinicalTrials.gov
Adrenergic alpha-Antagonists. Adrenergic Antagonists. Adrenergic Agents. Neurotransmitter Agents. Molecular Mechanisms of ... Serotonin 5-HT2 Receptor Antagonists. Serotonin Antagonists. Serotonin Agents. Dopamine D2 Receptor Antagonists. Dopamine ... Subject with Type 2 diabetes is eligible for study inclusion if the following condition is met at screening:. if a subject is ... An anchored Likert scale from 1-7, where values of 2 and above indicate the presence of progressively more severe symptoms, is ...
  https://clinicaltrials.gov/ct2/show/NCT01435928
*  Role of adrenergic alpha-2-receptors on feeding behavior in layer-type chicks.
Intracerebroventricular injection of the adrenergic alpha-2-receptor agonist, clonidine, stimulated food intake. ... The present study was designed to investigate the role of brain adrenergic alpha-2-receptors on feeding regulation of layer- ... 0/Adrenergic alpha-Agonists; 0/Adrenergic alpha-Antagonists; 0/Neuropeptide Y; 0/Neurotransmitter Agents; 0/Receptors, ... Adrenergic alpha-Agonists / pharmacology. Adrenergic alpha-Antagonists / pharmacology. Animals. Chickens / physiology*. ...
  http://www.biomedsearch.com/nih/Role-adrenergic-alpha-2-receptors/19233186.html
*  ChemIDplus - 367514-88-3 - NEKCRUIRPWNMLK-SCIYSFAVSA-N - Lurasidone hydrochloride [USAN] - Similar structures search, synonyms,...
SEROTONIN 5-HT2 RECEPTOR ANTAGONIST, serotonin 5-HT7 receptor antagonist, and antagonist of the adrenergic ?2A and ?2C ... A thiazole derivative and atypical ANTIPSYCHOTIC AGENT that functions as a DOPAMINE D2 RECEPTOR ANTAGONIST; ... and 5-HT7 Receptors as Well as Dopamine D2 Receptors) ... Adrenergic alpha-2 Receptor Antagonists. *. Adrenergic alpha- ... receptors, as well as a partial SEROTONIN 5-HT1A RECEPTOR AGONIST. It is used in the treatment of SCHIZOPHRENIA and BIPOLAR ...
  https://chem.nlm.nih.gov/chemidplus/rn/367514-88-3
*  Ipsen gives back rights to Santhera's PD drug - PharmaTimes
Santhera has regained the rights to fipamezole, its first-in-class selective adrenergic alpha-2 receptor antagonist for the ...
  http://www.pharmatimes.com/news/ipsen_gives_back_rights_to_santheras_pd_drug_975846
*  US Neuropathic Pain Market Value Doubles to $5 Billion by 2018 - MASSAGE Magazine
... an opioid receptor agonist/norepinephrine reuptake inhibitor tapentadol (Ortho-McNeil); a dopamine receptor agonist sodium ... a sodium channel antagonist mexiletine (Boehringer Ingelheim); three glutamate / NMDA antagonists ketamine intranasal (Javelin ... an alpha-2 adrenergic receptor antagonist/norepinehrine reuptake inhibitor reboxetine (Pfizer); ... Eighteen drugs are in Phase III development in the US including two GABA receptor agonists pregabalin (Pfizer) and gabapentin ...
  https://www.massagemag.com/us-neuropathic-pain-market-value-doubles-to-5-billion-by-2018-2299/
*  Main Study of Lofexidine and Methadone Pharmacodynamic Interaction in Methadone Maintained Patients - Full Text View -...
Narcotic Antagonists. Adrenergic alpha-2 Receptor Agonists. Adrenergic alpha-Agonists. Adrenergic Agonists. Adrenergic Agents. ... Up to 2 grams per day of acetaminophen is allowed at the discretion of the principal investigator or his designee. ... Lofexidine HCl 0.2 mg tablets titrated in ascending doses of 0.2 mg (1 tablet) QID starting at 0.4 mg (2 tablets) QID [e.g. Day ... Lofexidine Area Under the Curve (AUC) [ Time Frame: plateau days pre-dose, 0.5, 1 , 2, 3, 4, and 5 hours post dose ]. AUC will ...
  https://clinicaltrials.gov/ct2/show/NCT01650649?recr=Open&intr=methadone&rank=20
*  Lofexidine for Inpatient Opiate Detox - Full Text View - ClinicalTrials.gov
Narcotic Antagonists. Adrenergic alpha-2 Receptor Agonists. Adrenergic alpha-Agonists. Adrenergic Agonists. Adrenergic Agents. ... Lofexidine is an alpha2-adrenergic-agonist with mild to moderate antihypertensive actions. It is mainly used in the alleviation ... Have a score greater than or equal to 2 on the Objective Opiate Withdrawal Scale-Handelsman (OOWS) immediately prior to ... 2 above), anticonvulsants, antihypertensives, antiarrhythmics, antiretroviral, and cholesterol lowering medications. Nicotine ...
  https://clinicaltrials.gov/ct2/show/NCT00235729
*  Yohimbe bark extract (Pausinystalia johimbe) | Plant Profiler | Sigma-Aldrich
Assessment of alpha 2 adrenergic autoreceptor function in humans: effects of oral yohimbine. Life Sci 1982;30(23):2033-2041. ... It is significantly more active at presynaptic adrenoceptors than postsynaptic receptors. This action blocks the decrease in ... and peripherally to increase the release of norepinephrine from adrenergic nerve terminals. This increases the plasma ... Alpha 2-antagonist compounds and lipid mobilization: evidence for a lipid mobilizing effect of oral yohimbine in healthy male ...
  https://www.sigmaaldrich.com/life-science/nutrition-research/learning-center/plant-profiler/pausinystalia-johimbe.html
*  Yohimbine - wikidoc
Yohimbine Hydrochloride is a selective competitive alpha2-adrenergic receptor antagonist. The alpha2 receptor is responsible ... Since yohimbine is an antagonist, it will decrease the effects of these receptors, thus causing excitation, vasodilation, and ... Yohimbine and Yohimbine bark may also cause vasodilation through endothelin B receptor stimulation and nitric oxide (NO) ... Yohimbine also antagonizes several serotonin receptor subtypes: 1A (inhibitory, behavioral control), 1B (inhibitory, ...
  http://www.wikidoc.org/index.php/Yohimbe
*  Evidence for the Role of Membrane Receptor Lateral Movement in GTP-Binding Protein-Mediated Signal Transduction | SpringerLink
... direct measurements indicate that plasma membrane polypeptide hormone receptors are mobile within the plane of the lipid ... Agonist and antagonist binding to alpha 2-adrenergic receptors in purified mem branes from human platelets. Implications of ... Role of fry subunits of G proteins in targeting the (3-adrenergic receptor kinase to membrane-bound receptors. Science 1992; ... multiple sites of regulation by 3-adrenergic receptor and Mg-' studied in reconstituted receptor-G, vesicles. J Biol Chem 1986 ...
  https://link.springer.com/chapter/10.1007/978-1-4757-0680-2_5
*  A Category Names List - Drug Information Portal - U.S. National Library of Medicine
Adrenergic alpha-1 Receptor Antagonists (16) • Drugs that bind to and block the activation of ADRENERGIC ALPHA-1 RECEPTORS. ... Adrenergic alpha-Antagonists (65) • Drugs that bind to but do not activate alpha-adrenergic receptors thereby blocking the ... Adrenergic alpha-1 Receptor Agonists (7) • Compounds that bind to and activate ADRENERGIC ALPHA-1 RECEPTORS. MeSH ... Adrenergic Antagonists (132) • Drugs that bind to but do not activate ADRENERGIC RECEPTORS. Adrenergic antagonists block the ...
  https://druginfo.nlm.nih.gov/drugportal/drug/categories
*  Plus it
The 5HT1 receptor-selective antagonist methiothepin, but not ketanserin (5HT2-selective) or ICS-205,930 (5HT3-selective), ... The nonselective alpha-adrenergic agonist oxymetazoline inhibits parathyroid hormone (PTH)-stimulated cAMP production in intact ... Desensitization of alpha 2-receptor-mediated inhibition of cAMP production by epinephrine did not alter the response to either ... a receptor in OK cells that is negatively coupled to adenylate cyclase but distinct from the alpha 2-adrenergic receptor. Prior ...
  http://molpharm.aspetjournals.org/content/34/1/1
*  Rauvolscin - Википедија, слободна енциклопедија
Perry BD, U'Prichard DC (1981). „[3H]rauwolscine (alpha-yohimbine): a specific antagonist radioligand for brain alpha 2- ... adrenergic receptors". European Journal of Pharmacology. 76 (4): 461-4. PMID 6276200. doi:10.1016/0014-2999(81)90123-0.. ... Rauvolscin deluje predominantno kao antagonist α2-adrenergičnog receptora.[2] On takođe deluje kao parcijalni agonist 5-HT1A ... Wainscott DB, Sasso DA, Kursar JD, Baez M, Lucaites VL, Nelson DL (1998). „[3H]Rauwolscine: an antagonist radioligand for the ...
  https://sr.wikipedia.org/wiki/Rauvolscin
*  Boldine - Mr Supplement Australia
"Adrenergic Receptor Function in Fat Cells." Am J Clin Nutr. 55.1 (1992): 228S-36S.. (3) O'Brien P, Carrasco-Pozo C, Speisky H. ... 1)Eltze M, Grebe T, Michel MC, Czyborra P, Ullrich B. Affinity profile at alpha(1)- and alpha(2)-adrenoceptor subtypes and in ... Boldine has been shown to act as an alpha-2 adrenergic receptor antagonist. In English it's not that much simpler - boldine ... Furthermore, it is believed that the inactivation of these receptors, which are highly concentrated on fat cells, is something ...
  https://www.mrsupplement.com.au/boldine-boldo-lindera
*  Fipamezole in Neurogenic Orthostatic Hypotension - Tabular View - ClinicalTrials.gov
Fipamezole is a new antagonist of the pre-synaptic adrenergic alpha-2 receptors and is being investigated for potential use as ... to vascular adrenergic receptors, either because of blunted CNS control or impaired function of postganglionic sympathetic ... Adrenergic alpha-2 receptors inhibit noradrenaline and some other neurotransmitter release from nerve terminals in a tonic ... Alpha-2 receptors are located widely in the body, both in the central nervous system (CNS) and periphery. Pharmacological ...
  https://clinicaltrials.gov/ct2/show/record/NCT00758849
*  Table of Contents - August 01, 1990, 254 (2) | Journal of Pharmacology and Experimental Therapeutics
Prostaglandin synthesis elicited by adrenergic stimuli in rabbit aorta is mediated via alpha-1 and alpha-2 adrenergic receptors ... Adaptation of brain 5HT2 receptors after mianserin treatment: receptor sensitivity, not receptor binding, more accurately ... RG 12915: a potent 5-hydroxytryptamine-3 antagonist that is an orally effective inhibitor of cytotoxic drug-induced emesis in ... Endothelin receptor-coupling mechanisms in vascular smooth muscle: a role for protein kinase C. N R Danthuluri and T A Brock ...
  http://jpet.aspetjournals.org/content/254/2
*  Internet Scientific Publications
It is a competitive selective Alpha-2 adrenergic receptor antagonist, which readily enters CNS, and has peripheral and central ... 2. Whereas both groups acknowledge that at least in the short term (6 months), testosterone therapy is safe, with only ... 2. Basson R. Women's Sexuality and Sexual Dysfunction. In: Gibbs RS, Karlan BY, Haney AF, Nygaard IE. Eds. Danforth's ... Menopause is associated with a variety of endocrine changes (1). These lead to a reduction in sexuality and well-being (2). The ...
  http://ispub.com/IJGO/12/2/6043
*  Modeling Stress-precipitated Smoking Behavior for Medication Development - Full Text View - ClinicalTrials.gov
Adrenergic alpha-1 Receptor Antagonists. Adrenergic alpha-Antagonists. Adrenergic alpha-2 Receptor Agonists. Adrenergic alpha- ... Adrenergic beta-Antagonists. Adrenergic Antagonists. Adrenergic Agents. Neurotransmitter Agents. Molecular Mechanisms of ... The starting dose is 12.5 mg/day for day 1, followed by 25 mg/day for days 2-3, followed by 50 mg from days 4 to the end of the ... The starting dose is 0.5 mg/day for days 1-3, followed by 1.5mg/day for days 4-7, followed by 2 mg/day for days 8-12, followed ...
  https://clinicaltrials.gov/ct2/show/NCT00773357?term=Smoking&recr=Open&rank=16
*  Neurotransmitter Modulation of Neuronal Damage Following Cerebral Ischemia: Effects on Protein Ubiquitination | SpringerLink
Block, G.A., Pulsinelli, W.A. (1987) Excitatory amino acid receptor antagonists: Failure to prevent ischemic neuronal damage. J ... or post-treated with the non-competitive NMDA antagonist MK-801. In contrast, using an alpha 2-adrenergic receptor antagonist, ... using antagonist against the N-methyl-d-aspartate (NMDA) receptor. However, we have not been able to demonstrate a decrease in ... which cannot be blocked by noncompetitive NMDA receptor antagonist. This enhanced calcium entry can possibly be inhibited by ...
  https://link.springer.com/chapter/10.1007/978-1-4684-5562-5_34
*  Selective modification of renal alpha 2-adrenergic receptors in Milan hypertensive rat strain. | Hypertension
Binding of the selective alpha 1-adrenergic antagonist [3H]prazosin and the alpha 2-adrenergic antagonist [3H]rauwolscine was ... Cerebral and renal alpha-adrenergic receptors play an important role in the control of blood pressure. We studied alpha- ... In the cerebral cortex, no between-strain differences in alpha 1-adrenergic and alpha 2-adrenergic receptor density and ... adrenergic receptors in the cerebral and renal cortex of Milan hypertensive strain (MHS) and normotensive strain (MNS) rats, a ...
  http://hyper.ahajournals.org/content/10/5/505