Immunologic adjuvant - Wikipedia
Look up adjuvant in Wiktionary, the free dictionary. Scholia has a profile for immunologic adjuvant (Q967453). Adjuvant therapy ... The word "adjuvant" comes from the Latin word adiuvare, meaning to help or aid. "An immunologic adjuvant is defined as any ... Sasaki S, Okuda K (2000). "The Use of Conventional Immunologic Adjuvants in DNA Vaccine Preparations". In Lowrie DB, Whalen RG ... Aluminium salts are the most commonly-used adjuvants in human vaccines. Their adjuvant activity was described in 1926. The ...
Lithium chloride, an immunologic adjuvant<...
Lithium chloride, an immunologic adjuvant. / Shenkman, L.; Borkowsky, W.; Holzman, R. S. et al. In: Clinical Research, Vol. 24 ... Shenkman L, Borkowsky W, Holzman RS, Shopsin B. Lithium chloride, an immunologic adjuvant. Clinical Research. 1976;24(5):634A. ... Shenkman, L., Borkowsky, W., Holzman, R. S., & Shopsin, B. (1976). Lithium chloride, an immunologic adjuvant. Clinical Research ... Shenkman, L, Borkowsky, W, Holzman, RS & Shopsin, B 1976, Lithium chloride, an immunologic adjuvant, Clinical Research, vol. ...
Flow-cytometric studies with eleutherococcus senticosus extract as an immunomodulatory agent
Adjuvants, Immunologic* * Antibodies, Monoclonal / pharmacology * Double-Blind Method * Female * Flow Cytometry * Humans ...
A heat shock protein based polyvalent vaccine targeting HSV-2: CD4(+) and CD8(+) cellular immunity and protective efficacy
Adjuvants, Immunologic / administration & dosage * Animals * CD4-Positive T-Lymphocytes / immunology* * CD8-Positive T- ... Optimal T cell stimulation was dependent on the synergistic adjuvant properties of QS-21 with hsp70. The vaccine provided ... complexed non-covalently to the HSP70 chaperone and formulated with QS-21 saponin adjuvant. HerpV is observed to be immunogenic ...
ACIP: General Recommendations on Immunization
Adjuvants. Many antigens evoke suboptimal immunologic responses. Efforts to enhance immunogenicity include mixing antigens with ... Immunologic investigations with oral live typhoid vaccine Ty21a strain. In: Steffen R, Lobel HO, Bradley DJ, eds. Travel ... Preparations with adjuvants should be administered intramuscularly. && Td = tetanus and diphtheria toxoids for use among ... In general, vaccines containing adjuvants should be injected into the muscle mass; when administered subcutaneously or ...
Vaccine adjuvants - understanding molecular mechanisms to improve vaccines | Swiss Medical Weekly
Divergent therapeutic and immunologic effects of oligodeoxynucleotides with distinct CpG motifs. J Immunol. 2001;167(9):4878-86 ... CpG ODN and ISCOMATRIX adjuvant: a synergistic adjuvant combination inducing strong T-Cell IFN-gamma responses. Biomed Res Int ... Development and characterization of synthetic glucopyranosyl lipid adjuvant system as a vaccine adjuvant. PLoS One. 2011;6(1): ... Evidence of increased clinical protection of an MF59-adjuvant influenza vaccine compared to a non-adjuvant vaccine among ...
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Eating Dirt - Volume 9, Number 8-August 2003 - Emerging Infectious Diseases journal - CDC
... likely make at least passable immunologic adjuvants. For all these reasons, clays might act as vaccines. And the IgA antibodies ... For decades we have used aluminum salts, like those found in clays, as adjuvants in human and animal vaccines. Adjuvants are ... Aluminum compounds as vaccine adjuvants. Adv Drug Deliv Rev. 1998;32:155-72. DOIPubMedGoogle Scholar ... Immunologic Development and Infectious Disease The "Age of Bacteria" Chimayo Cite This Article ...
Prasarini Thailam (Oil) - Benefits, Usage, Indications and Dosage
Safety, Correlative Markers, and Clinical Results of Adjuvant Nivolumab in Combination with Vaccine in Resected High-Risk...
Conclusions: Nivolumab with vaccine is well tolerated as adjuvant therapy and demonstrates immunologic activity with promising ... Although the results cannot be compared directly with the prior adjuvant interferon and current adjuvant ipilimumab experience ... Adjuvant therapy for resected high-risk melanoma continues to be an area in need of more effective strategies. Patients with ... Adjuvant therapy with pegylated interferon alfa-2b versus observation alone in resected stage III melanoma: final results of ...
Lee M. Wetzler, M.D. | Virology, Immunology & Microbiology
We have also begun a systems immunologic analysis of the adjuvant activity of PorB. We have found that PorB induces a genetic ... We are also comparing the PorB adjuvant activity to other classical and investigative adjuvants including Alum, MF59, CpG DNA ... We are investigating the use of this TLR2 ligand, PorB, as a vaccine adjuvant using classic antigens i.e. OVA, and more ... We have shown that PorB adjuvant activity is absolutely MyD88 dependent and also largely dependent on the presence of TLR2 ( ...
Prevention of Pertussis, Tetanus, and Diphtheria with Vaccines in the United States: Recommendations of the Advisory Committee...
Pentacel (Sanofi Pasteur) (DTaP-IPV/Hib): The immunologic response of all antigens in Pentacel (diphtheria and tetanus toxoids ... Antitoxin response of pregnant women to adjuvant and plain toxoids. Bull World Health Organ 1965;32:683-97. PubMedexternal icon ... Pediarix (GSK) (DTaP-HepB-IPV): The immunologic response of all antigens in Pediarix (diphtheria and tetanus toxoids; pertussis ... The immunologic basis of immunization series-Module 3: tetanus update 2006. Geneva, Switzerland: World Health Organization; ...
Ofer Levy | Vaccine Congress USA
... leveraging robotic and immunologic approaches to discover, characterize, and formulate novel small molecule adjuvants that may ... PVP faculty lead several NIH/NIAID-supported studies, including: (a) Adjuvant Discovery and Development Program contracts, ... adjuvant screening/discovery, systems biology, animal studies, and clinical trials to accelerate and de-risk development of ...
環磷醯胺對於結合GVAX疫苗合併治療子
Trial to evaluate the immunogenicity and safety of a melanoma helper peptide vaccine plus incomplete Freund's adjuvant,...
Immunologic and clinical outcomes of a randomized phase II trial of two multipeptide vaccines for melanoma in the adjuvant ... Immunologic hierarchy, class II MHC promiscuity, and epitope spreading of a melanoma helper peptide vaccine. Cancer Immunol ... Studies to optimize adjuvants and strategies cannot be performed efficiently with neo-antigens, because the patient specificity ... These data add to findings from others for the value of TLR agonists in vaccine adjuvants. A hepatitis B virus vaccine ( ...
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Breast Cancer Vaccine Trial: What You Need to Know with Dr. Thomas Budd | Cleveland Clinic
The particular immunologic adjuvant we use could be used with other proteins, so that I think there is a future for this ... We give the protein plus another drug called an immunologic adjuvant that kind of tells the immune system, Hey, take a look at ... So it could be a so-called immunologic target, where you can stimulate the immune system to attack cells and make too much of ... but also the immunologic response. The end points were really looking at are side effects and whether we can detect an immune ...
New Revelation - The Neurotoxin Far Worse than Mercury… Posted By Dr. Mercola - Truth Seeker Forum
But vaccines also contain adjuvants - agents that stimulate your immune system to greatly increase immunologic response to the ... Like other adjuvants, aluminum is added to the vaccine in order to boost your immune response to the antigen. The antigen is ... Ayoub in its entirely to learn more about the dangers of this common vaccine adjuvant. You can also read Aluminum in Vaccines ... Aluminum is the most commonly used vaccine adjuvant and may actually be as dangerous as mercury.. Aluminum in vaccines is ...
SciELO - Brazil - Physicochemical features, functional characteristics, and health benefits of cottonseed oil: a review...
... it is very crucial to conduct research work and develop novel immunologic adjuvants that possess very minute toxicity for the ... Based on this idea, an experiment on cottonseed oil has shown to have adjuvant effect on the humoral response, thus motivating ... 40-42.). Such responses may be achieved by using vegetable oils as they are the probable adjuvant sources. The supreme ... The careful selection of adjuvants can affect certain features of antibody response like epitope specificity, affinity, class ...
Immunologic and Clinical Responses after Vaccinations with Peptide-Pulsed Dendritic Cells in Metastatic Renal Cancer Patients |...
... that have been reported to be immunogenic when used as adjuvant (19). Furthermore, in our in vitro analysis, we found that the ... Immunologic and Clinical Responses after Vaccinations with Peptide-Pulsed Dendritic Cells in Metastatic Renal Cancer Patients ... Clinical and immunologic results of a randomized phase II trial of vaccination using four melanoma peptides either administered ... This study shows that MUC1 peptide-pulsed dendritic cells can induce clinical and immunologic responses in patients with ...
Frontiers | Emerging Therapeutics for Immune Tolerance: Tolerogenic Vaccines, T cell Therapy, and IL-2 Therapy
FK506 as an adjuvant of tolerogenic DNA vaccination for the prevention of experimental autoimmune encephalomyelitis. J Gene Med ... Efficacy and immunologic effects of extracorporeal photopheresis plus interleukin-2 in chronic graft-versus-host disease. Blood ... For example, the cytokine GM-CSF has been used as a tolerogenic adjuvant and a DC targeting moiety to suppress EAE. Peptides ... IFN-β was used as a tolerogenic adjuvant and carrier protein because of its ability to suppresses T cell priming, inhibit Tcon ...
Aluminum Toxicity: Practice Essentials, Pathophysiology, Etiology
A number of vaccines contain aluminum salts as adjuvants. As a result, fully vaccinated children are exposed to up to 4 mg of ... Other organic manifestations of aluminum intoxication have been proposed, such as a slightly poorer immunologic response to ... Inbar et al posited that data on vaccine-related aluminum toxicity may have been limited by the use of aluminum adjuvants as ... 26] However, adjuvant aluminum in vaccines has been reported to cause local inflammatory reactions (eg, erythema, subcutaneous ...
Administration of Vaccines in Animals - Pharmacology - Merck Veterinary Manual
The interval between vaccine doses depends on an animals immunologic memory. The duration of this memory depends on multiple ... factors, such as the nature of the antigen, the use of live or dead organisms, the adjuvants used, and the route of ... Modified live vaccines, however, may induce a protective primary immune response and some immunologic memory. Because the ...
Global gene expression profiles in fibroblasts from synovial, skin and lymphoid tissue reveals distinct cytokine and chemokine...
TILs Clinical Trial Provides Hope for Cervical Carcinoma Patients | Moffitt
NIH Clinical Center: Search the Studies
TLR4-mediated release of heparin-binding protein in human airways : a co-stimulatory role for IL-26 | Lund University...
Prevalence of active cytomegalovirus infection at diagnosis of ovarian cancer and during chemotherapy and subsequent changes in...
... during and after front-line adjuvant chemotherapy. Serum CMV DNA levels were assessed using digital PCR; >100 copies/mL of ... Immunologic monitoring in Breast cancer patients receiving postoperative adjuvant chemotherapy. Cancer. 1981;48(9):1996-2002. ... Shilling V, Jenkins V. Self-reported cognitive problems in women receiving adjuvant therapy for Breast cancer. Eur J Oncol Nurs ... during and after front-line adjuvant chemotherapy. Serum CMV DNA levels were assessed using digital PCR; ,100 copies/mL of ...