*  Irisin Stimulates Browning of White Adipocytes Through Mitogen-Activated Protein Kinase p38 MAP Kinase and ERK MAP Kinase...
White adipocytes store energy (e.g., triglycerides), whereas brown adipocytes consume energy (5,6). Many studies have shown ... A: Expression of brown/beige adipocyte marker, betatrophin, and white adipocyte marker (aP2 and adipoq) genes were measured by ... Irisin stimulates adipocyte browning via p38/ERK pathways. Primary rat adipocytes and 3T3-L1-derived adipocytes were treated ... To investigate the browning effect of r-irisin on adipocytes, we used both 3T3-L1-derived adipocytes and primary rat adipocytes ...
  http://diabetes.diabetesjournals.org/content/63/2/514.full
*  Abstract 52: Capsaicin Activates the Trpv1-camkii-ampk-sirt-1-dependent Mechanism to Trigger Brown Remodeling of White...
Capsaicin Activates the Trpv1-camkii-ampk-sirt-1-dependent Mechanism to Trigger Brown Remodeling of White Adipocytes to ... Capsaicin Activates the Trpv1-camkii-ampk-sirt-1-dependent Mechanism to Trigger Brown Remodeling of White Adipocytes to ... Capsaicin Activates the Trpv1-camkii-ampk-sirt-1-dependent Mechanism to Trigger Brown Remodeling of White Adipocytes to ... Capsaicin Activates the Trpv1-camkii-ampk-sirt-1-dependent Mechanism to Trigger Brown Remodeling of White Adipocytes to ...
  http://atvb.ahajournals.org/content/35/Suppl_1/A52
*  Frontiers | TGF-β/Smad3 Signaling Regulates Brown Adipocyte Induction in White Adipose Tissue | Endocrinology
Here we review the data supporting this phenomenon and put into perspective the promise of conversion of white fat to a brown ... Here we review the data supporting this phenomenon and put into perspective the promise of conversion of white fat to a brown ... role played by the TGF-beta/Smad3 signaling pathway in modulating the appearance of brown adipocytes in traditional white fat, ... role played by the TGF-beta/Smad3 signaling pathway in modulating the appearance of brown adipocytes in traditional white fat, ...
  https://www.frontiersin.org/articles/10.3389/fendo.2012.00035/full
*  Frontiers | Oxygen Deprivation and the Cellular Response to Hypoxia in Adipocytes - Perspectives on White and Brown Adipose...
We suggest that obesity-linked hypoxia may lead to similar alterations in brown adipocytes as in white fat cells - particularly ... We suggest that obesity-linked hypoxia may lead to similar alterations in brown adipocytes as in white fat cells - particularly ... and this leads to substantial changes in white adipocyte function. These changes include increased production of inflammation- ... and this leads to substantial changes in white adipocyte function. These changes include increased production of inflammation- ...
  https://www.frontiersin.org/articles/10.3389/fendo.2015.00019/full
*  Enhancing Energy Expending Adipocytes in White Adipose Tissue - Stephen Farmer
... within white adipose (WAT) adipocytes. There are two major types of adipose, white that stores TGs and brown (BAT) that ... Enhancing Energy Expending Adipocytes in White Adipose Tissue Farmer, Stephen Robert Boston University, Boston, MA, United ... Enhancing Energy Expending Adipocytes in White Adipose Tissue. Farmer, Stephen Robert / Boston University. $497,778. ... Enhancing Energy Expending Adipocytes in White Adipose Tissue. Farmer, Stephen Robert / Boston University. $434,920. ...
  http://grantome.com/grant/NIH/R01-DK098830-02S1
*  Angiotensin type 2 receptor activation promotes browning of white adipose tissue and brown adipogenesis | Signal Transduction...
AT2R expression in white adipocyte is upregulated by thyroid hormone T3. Human white adipocytes (day 14) were treated without ... pathway in white adipocytes.. Figure 3. Signaling pathways underlying the AngII-AT2R-induced browning of white adipocytes. (a-c ... adipocyte protein 2 (aP2)). To quantify the number of white adipocytes with multilocular appearance (adipocytes with the ... AT2R activation increases UCP1 and CITED1 expressions in white adipocytes. (a and b) Mouse white adipose cells (day 4) were ...
  https://www.nature.com/articles/sigtrans201722?error=cookies_not_supported&code=e9eb300c-2774-48c4-92a8-0f416b0c1191
*  Healthier White Adipose by Recruitment of Beige/Brite Adipocytes - Stephen Farmer
... within white adipose (WAT) adipocytes. There are two major types of adipose, white that stores TGs and brown (BAT) that ... Healthier White Adipose by Recruitment of Beige/Brite Adipocytes Farmer, Stephen Robert Boston University, Boston, MA, United ... Healthier White Adipose by Recruitment of Beige/Brite Adipocytes. Farmer, Stephen Robert / Boston University. $327,810. ... Healthier White Adipose by Recruitment of Beige/Brite Adipocytes. Farmer, Stephen Robert / Boston University. ...
  http://grantome.com/grant/NIH/R01-DK102199-01
*  Plus it
2G). Immunohistochemistry showed that the FLAGΔ256 was mainly expressed in the nucleus of white adipocytes (Fig. 2H). Body ... Overexpression of the mutant FoxO1 in WAT affects size and gene expression of white adipocytes.. To investigate the mechanism ... Adipocyte Liver Kinase b1 Suppresses Beige Adipocyte Renaissance Through Class IIa Histone Deacetylase 4 ... Troglitazone increases the number of small adipocytes without the change of white adipose tissue mass in obese Zucker rats. J ...
  http://diabetes.diabetesjournals.org/content/57/3/563
*  Protein must exist in specific brain cells to prevent diet-induced obesity, UT Southwestern researchers find - Healthcanal.com ...
White adipocytes primarily store fat.. "When SIRT1 is present in POMC neurons, the neurons properly convey a signal from leptin ... In addition, the researchers found that SIRT1 must be present in POMC neurons for leptin to stimulate the remodeling of white ... "The drawback to harnessing adrenergic receptors to make more brown adipocytes, as a lot of people are thinking about doing, is ... and that could trigger the remodeling of white fat into brown fat - has high potential. ...
  https://www.healthcanal.com/brain-nerves/9154-protein-must-exist-in-specific-brain-cells-to-prevent-diet-induced-obesity-ut-southwestern-researchers-find.html
*  FOXC2 Gene - GeneCards | FOXC2 Protein | FOXC2 Antibody
Visceral White Adipocytes Visceral White Adipose * Sacral Brown Adipocyte Cells Sacral Brown Adipose Depot ...
  http://www.genecards.org/cgi-bin/carddisp.pl?gene=FOXC2
*  ATP6V0E2 Gene - GeneCards | VA0E2 Protein | VA0E2 Antibody
Visceral White Adipocytes Visceral White Adipose *span" data-trigger="SectionLoaded"> Gut Tube (Gastrointestinal Tract) * ...
  http://www.genecards.org/cgi-bin/carddisp.pl?gene=ATP6V0E2
*  ZNF365 Gene - GeneCards | ZN365 Protein | ZN365 Antibody
Visceral White Adipocytes Visceral White Adipose *span" data-trigger="SectionLoaded"> Eye (Sensory Organs) * Lens ...
  http://www.genecards.org/cgi-bin/carddisp.pl?gene=ZNF365
*  HELZ2 - Helicase with zinc finger domain 2 - Homo sapiens (Human) - HELZ2 gene & protein
R-HSA-381340. Transcriptional regulation of white adipocyte differentiation. R-HSA-400206. Regulation of lipid metabolism by ... R-HSA-381340. Transcriptional regulation of white adipocyte differentiation. R-HSA-400206. Regulation of lipid metabolism by ... "THRAP3 interacts with HELZ2 and plays a novel role in adipocyte differentiation.". Katano-Toki A., Satoh T., Tomaru T., Yoshino ... "THRAP3 interacts with HELZ2 and plays a novel role in adipocyte differentiation.". Katano-Toki A., Satoh T., Tomaru T., Yoshino ...
  http://www.uniprot.org/uniprot/Q9BYK8
*  MED8 - Mediator of RNA polymerase II transcription subunit 8 - Homo sapiens (Human) - MED8 gene & protein
R-HSA-381340. Transcriptional regulation of white adipocyte differentiation. Miscellaneous databases. The Gene Wiki collection ... R-HSA-381340. Transcriptional regulation of white adipocyte differentiation. UniPathway: a resource for the exploration and ... Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys). Callithrix jacchus (White-tufted-ear marmoset). ...
  http://www.uniprot.org/uniprot/Q96G25
*  Cell Research - Fat poetry: a kingdom for PPAR[gamma]
Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma. Nature 2004; 429:771-776. , Article , PubMed , ... Both adipocyte number and adipocyte size are major contributors to adipose tissue mass. Therefore, adipocyte differentiation is ... Peroxisome proliferator-activated receptor gamma is required in mature white and brown adipocytes for their survival in the ... Hansen JB, Kristiansen K. Regulatory circuits controlling white versus brown adipocyte differentiation. Biochem J 2006; 398:153 ...
  http://www.nature.com/cr/journal/v17/n6/full/cr200748a.html?error=cookies_not_supported&code=c8817324-0a7b-4818-898b-dc15fdc25710
*  Plus it
Emergence of brown adipocytes in white fat in mice is under genetic control. Effects on body weight and adiposity. J Clin ... Identification of white adipocyte progenitor cells in vivo. Cell 2008;135:240-249pmid:18835024. ... Programming human pluripotent stem cells into white and brown adipocytes. Nat Cell Biol 2012;14:209-219pmid:22246346. ... Identification of inducible brown adipocyte progenitors residing in skeletal muscle and white fat. Proc Natl Acad Sci U S A ...
  http://diabetes.diabetesjournals.org/content/64/11/3713
*  CDK19 Gene - GeneCards | CDK19 Protein | CDK19 Antibody
Transcriptional regulation of white adipocyte differentiation .40 2. Metabolism. Metabolism .37 Metabolism of lipids and ...
  http://www.genecards.org/cgi-bin/carddisp.pl?gene=CDK19
*  CARM1 Gene - GeneCards | CARM1 Protein | CARM1 Antibody
Transcriptional regulation of white adipocyte differentiation .40 3. RNA Polymerase II Transcription Initiation And Promoter ... promotes adipocyte differentiation and the accumulation of brown fat tissue. Plays a role in the regulation of pre-mRNA ... promotes adipocyte differentiation and the accumulation of brown fat tissue. Plays a role in the regulation of pre-mRNA ...
  http://www.genecards.org/cgi-bin/carddisp.pl?gene=CARM1
*  CDK8 Gene - GeneCards | CDK8 Protein | CDK8 Antibody
Transcriptional regulation of white adipocyte differentiation .40 3. Transcriptional activity of SMAD2/SMAD3-SMAD4 heterotrimer ...
  http://www.genecards.org/cgi-bin/carddisp.pl?gene=CDK8
*  CHD9 Gene - GeneCards | CHD9 Protein | CHD9 Antibody
Transcriptional regulation of white adipocyte differentiation .40 3. Regulation of cholesterol biosynthesis by SREBP (SREBF). ...
  http://www.genecards.org/cgi-bin/carddisp.pl?id_type=entrezgene&id=80205
*  UniProt: P01375
Transcriptional regulation of white adipocyte differentiation. DR Reactome; R-HSA-5357786; TNFR1-induced proapoptotic signaling ...
  http://www.genome.jp/dbget-bin/www_bget?uniprot:P01375
*  PPARA Gene - GeneCards | PPARA Protein | PPARA Antibody
Brown adipocyte-like cells(Nishio M et. al. 2012) * White adipocyte-like cells(Elabd C et. al. 2009) ...
  http://www.genecards.org/cgi-bin/carddisp.pl?gene=PPARA&keywords=hsa-mir-6731-5p
*  MED7 Gene - GeneCards | MED7 Protein | MED7 Antibody
Transcriptional regulation of white adipocyte differentiation .40 2. Gene Expression. Gene Expression ...
  http://www.genecards.org/cgi-bin/carddisp.pl?gene=MED7
*  HDAC3 Gene - GeneCards | HDAC3 Protein | HDAC3 Antibody
Transcriptional regulation of white adipocyte differentiation .40 5. p53 Signaling. p53 Pathway ...
  http://www.genecards.org/cgi-bin/carddisp.pl?gene=HDAC3