*  Induction of Bach1 and ARA70 gene expression at an early stage of adipocyte differentiation of mouse 3T3-L1 cells | Biochemical...
Induction of Bach1 and ARA70 gene expression at an early stage of adipocyte differentiation of mouse 3T3-L1 cells. Makoto ... Induction of Bach1 and ARA70 gene expression at an early stage of adipocyte differentiation of mouse 3T3-L1 cells ... Induction of Bach1 and ARA70 gene expression at an early stage of adipocyte differentiation of mouse 3T3-L1 cells ... Induction of Bach1 and ARA70 gene expression at an early stage of adipocyte differentiation of mouse 3T3-L1 cells ...
  http://www.biochemj.org/content/361/3/629
*  Tumor necrosis factor-alpha acutely inhibits insulin signaling in human adipocytes: implication of the p80 tumor necrosis...
This cross talk has now been investigated in human adipocytes at the level of phosphatidylinositol (PI) 3-kinase, and the TNF ... Equilibrium binding studies using human adipocytes from mammary tissue indicated the presence of two populations of TNFR with ... These findings indicate that in human adipocytes, low concentrations of TNF-alpha induce a rapid inhibition of insulin ... Tumor necrosis factor-alpha acutely inhibits insulin signaling in human adipocytes: implication of the p80 tumor necrosis ...
  http://diabetes.diabetesjournals.org/content/47/4/515.short
*  The Carb-Sane Asylum: Adipocyte Size & Adipokine Secretion
Relationship between Adipocyte Size and Adipokine Expression and Secretion. Context: Adipocytes are known to release a variety ... The results obtained by the technique clearly suggest that only the very large adipocytes are dysregulated. Adipocyte ... Something else that caught my eye: Recently, adipocyte size in the sc abdominal depot was identified to be a significant ... Design, Patients, and Main Outcome Measures: Protein secretion and mRNA expression in cultured adipocytes separated according ...
  http://carbsanity.blogspot.com/2010/10/adipocyte-size-adipokine-secretion.html
*  Human Preadipocytes-subcutaneous | Creative Bioarray
Adipocytes play an important role in energy storage and metabolism. Adipocyte differentiation is a developmental process that ... It has also been demonstrated that there is a close relationship between adipocyte differentiation and many physiological and ... Preadipocytes are present throughout adult life in adipose tissues and can proliferate and differentiate into mature adipocytes ...
  https://www.creative-bioarray.com/Human-Preadipocytes-subcutaneous-CSC-7736W-item-1791.htm
*  Plus it
In obesity, the differentiation of adipocytes is suppressed. Although adipocyte differentiation is associated with changes in ... The M2 isoform of PK (PKM2) is expressed in adipocytes but its role in adipogenesis is unknown. Here we demonstrate that PKM2 ... Abstract B36: Pyruvate kinase M2 regulates adipocyte differentiation and the expression of enzymes involved in glucose ... Overexpression of PKM2 suppressed adipocyte differentiation. In obesity, increased numbers of macrophages are found in adipose ...
  http://cancerpreventionresearch.aacrjournals.org/content/8/10_Supplement/B36
*  Ser-474 is the major target of insulin-mediated phosphorylation of protein kinase B beta in primary rat adipocytes.
... Göransson ... Taken together, these results show that rat adipocyte PKB beta mainly is phosphorylated on Ser-474 in response to insulin ... In this study, we have characterized the insulin-induced phosphorylation and activation of PKB beta in primary rat adipocytes. ... Adipocytes/drug effects/*enzymology, Animals, Cells; Cultured, Electrophoresis; Gel; Two-Dimensional, Enzyme Inhibitors/ ...
  http://uu.diva-portal.org/smash/record.jsf?pid=diva2:38200
*  Deficiency of Phosphoinositide 3-Kinase Enhancer Protects Mice From Diet-Induced Obesity and Insulin Resistance | Diabetes
First, the mature adipocyte marker aP2 is significantly decreased during in vitro adipocyte differentiation in PIKE−/− MEFs, ... PIKE is essential for adipocyte differentiation.. Under chow diet feeding conditions, expressions of mature adipocyte markers ... Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes. Nat Rev Mol Cell Biol 2008; 9: 367- 377. ... 2C). The adipocytes in PIKE−/− mice were also smaller in both feeding conditions (Fig. 2D and E). Moreover, circulating leptin ...
  http://diabetes.diabetesjournals.org/content/59/4/883?with-ds=yes
*  In vitro models of diabetes - FRAME
The FRAME Alternatives Laboratory cultures primary human adipocytes and skeletal muscle myotubes to study the effects of ...
  http://www.frame.org.uk/research-diabetes/
*  Protein kinase C isoforms ɛ, η, δ and ζ in murine adipocytes: expression, subcellular localization and tissue-specific...
3T3-L1 adipocytes express PKC-ε and -ζ, and PKC-ε expression increases with differentiation from preadipocytes to adipocytes. ... PMA treatment of adipocytes induces translocation of PKC-ε and -δ from the cytosol to the membrane fractions. Insulin treatment ... The PKC isoforms ε, η, δ and ζ are expressed in adipocytes. Immunoreactivity for all isoforms is higher in the membranes than ... Protein kinase C isoforms ɛ, η, δ and ζ in murine adipocytes: expression, subcellular localization and tissue-specific ...
  http://www.biochemj.org/content/316/3/865
*  Apolipoprotein E promotes lipid accumulation and differentiation in human adipocytes (Journal Article) | SciTech Connect
Interestingly, incubation of APOE-deficient hMSC-Tert adipocytes with conditioned media from APOE3-overexpressing adipocytes or ... but were unable to induce adipocyte differentiation, asmore » judged by expression of adipocyte markers. Taken together, ... However, little is yet known if APOE functions in a similar manner in human adipocytes. This prompted us to compare lipid ... Differentiated hMSC-Tert were stably transduced with or without siRNA targeting APOE while murine adipocytes were isolated from ...
  https://www.osti.gov/scitech/biblio/22462329-apolipoprotein-promotes-lipid-accumulation-differentiation-human-adipocytes
*  Plus it
Research Design and Methods: ApoE gene and protein expression in 3T3-L1 adipocytes, or mature adipocytes and adipose tissue ... Results: Oxidant stress in 3T3-L1 cells, or adipocytes and adipose tissue from lean mice significantly reduced apoE mRNA and ... Objective: Endogenous expression of apoE has a significant impact on adipocyte lipid metabolism and is markedly suppressed in ... Adipose tissue oxidant stress is emerging as an important mediator of adipocyte dysfunction. These studies were undertaken to ...
  http://diabetes.diabetesjournals.org/content/early/2008/08/04/db08-0592
*  Kindke's Scrap Notes: May 2015
... even small adipocytes contain the same amount of leptin as large adipocytes. And PPARg does not appear to predict adipocyte ... I would of expected larger adipocytes to have higher PPARg, and vice versa for the small adipocytes. *shrug* ). Depiste reduced ... the size distribution of adipocytes follows a Gaussian curve, but when you make insulin invisible to adipocytes, the size ... These data suggest an intrinsic heterogeneity of adipocytes with differences in gene expression related to adipocyte size and ...
  http://kindkehealthnotes.blogspot.com/2015/05/
*  Plus it
Some have proposed that the generation of new adipocytes may be balanced by adipocyte death, with the constant and tightly ... Obesity in adults is typically associated with adipocyte hypertrophy, and an additional adipocyte hyperplasia occurs in ... in 3T3-L1 cells promotes adipocyte differentiation. IFN-γ not only rescued adipocyte differentiation but also decreased Coup- ... A: 3T3-L1 cells were induced to differentiate into adipocytes in the presence of 20 nmol/L SAG and/or 50 ng/mL IFN-γ or were ...
  http://diabetes.diabetesjournals.org/content/60/6/1668
*  Plus it
Thank you for your interest in spreading the word about Diabetes.. NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.. ...
  http://diabetes.diabetesjournals.org/content/66/Supplement_1/A487
*  Obesity, Metabolic Syndrome, and Adipocytes
... M. V. Dodson,1 P. S. Mir,2 G. J. Hausman,3 L. L. Guan,4 Min Du,1 Z. Jiang,1 M. E. ... M. V. Dodson, P. S. Mir, G. J. Hausman, et al., "Obesity, Metabolic Syndrome, and Adipocytes," Journal of Lipids, vol. 2011, ...
  https://www.hindawi.com/journals/jl/2011/721686/cta/
*  Adipocyte - Wikipedia
Marrow adipocytes, like brown and white adipocytes, are derived from mesenchymal stem cells. The marrow adipose tissue depot is ... Adipocytes are derived from mesenchymal stem cells which give rise to adipocytes, osteoblasts, myocytes and other cell types ... Pre-adipocytes are undifferentiated fibroblasts that can be stimulated to form adipocytes. Recent studies shed light into ... Most recently, the presence of beige adipocytes with a gene expression pattern distinct from either white or brown adipocytes ...
  https://en.wikipedia.org/wiki/Adipocyte
*  Adipocyte protein 2 - Wikipedia
aP2 (adipocyte Protein 2) is a carrier protein for fatty acids that is primarily expressed in adipocytes and macrophages. aP2 ... Shum BO, Mackay CR, Gorgun CZ, Frost MJ, Kumar RK, Hotamisligil GS, Rolph MS (2006). "The adipocyte fatty acid-binding protein ... "Human adipocyte lipid-binding protein: purification of the protein and cloning of its complementary DNA". Biochemistry. 28 (22 ... "Adipocyte/macrophage fatty acid binding proteins control integrated metabolic responses in obesity and diabetes". Cell Metab. 1 ...
  https://en.wikipedia.org/wiki/Adipocyte_protein_2
*  BMP7 Drives Human Adipogenic Stem Cells into Metabolically Active Beige Adipocytes | SpringerLink
The aim of this study was to confirm BMP7-derived human adipocytes as a relevant in vitro model of human beige adipocyte by ... Rosenwald M, Wolfrum C (2014) The origin and definition of brite versus white and classical brown adipocytes. Adipocyte 3:4-9 ... UCP1-containing adipocytes molecularly distinct from classic brown adipocytes. J Biol Chem 285:7153-7164PubMedCentralPubMed ... By confirming the cellular identity and metabolic activity, this BMP7-induced human beige adipocytes from hASC should aid in ...
  https://link.springer.com/article/10.1007/s11745-014-3981-9
*  Stevioside from Stevia rebaudiana Bertoni Increases Insulin Sensitivity in 3T3-L1 Adipocytes
To test effects of stevioside on insulin-sensitivity of 3T3-L1 adipocytes, its effects on glucose uptake by the adipocytes was ... α suppresses adipocyte-specific genes and activates expression of preadipocyte genes in 3T3-L1 adipocytes: nuclear factor-κB ... J. K. Sethi and G. S. Hotamisligil, "The role of TNFα in adipocyte metabolism," Seminars in Cell and Developmental Biology, vol ... 3.3.3. Glucose Uptake in TNF-α Induced Adipocytes. 3T3-L1 cells were induced to insulin resistance using TNF-α, to test whether ...
  https://www.hindawi.com/journals/ecam/2013/938081/
*  Consequence of Menin Deficiency in Mouse Adipocytes Derived by In Vitro Differentiation
The top 40 genes differentially expressed in the Men1-KO adipocytes (at least 3-fold change compared with WT adipocytes; ) were ... b) Expression of adipocyte marker genes. Conventional RT-PCR followed by agarose gel electrophoresis of the adipocyte marker ... These menin-deficient adipocytes and their corresponding normal adipocytes were analyzed for cell size, lipid content, and gene ... using RNA isolated from mESC-derived adipocytes showed 1.6- to 29-fold upregulation of 19 genes in menin-null adipocytes; the ...
  https://www.hindawi.com/journals/ije/2015/149826/
*  Ursolic Acid Inhibits Adipogenesis in 3T3-L1 Adipocytes through LKB1/AMPK Pathway
Adipocyte differentiation Is the Subject Area "Adipocyte differentiation" applicable to this article? Yes. No. ... Adipocytes Is the Subject Area "Adipocytes" applicable to this article? Yes. No. ... Adipose tissue is determined by the number and size of adipocytes. The increase in the number of adipocytes involves the ... Sirt1 inhibits adipogenesis by repressing PPARγ expression in cultured adipocytes [26] and decreases adipocyte formation during ...
  http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0070135
*  Regulation of vascular tone by adipocytes
... Nele Maenhaut (UGent) and Johan Van de Voorde (UGent) ... "Regulation of Vascular Tone by Adipocytes." Bmc Medicine 9 (25).. APA. Maenhaut, N., & Van de Voorde, J. (2011). Regulation of ... For example, the unidentified adipocyte-derived relaxing factor (ADRF) released from adipose tissue has been shown to relax ... For example, the unidentified adipocyte-derived relaxing factor (ADRF) released from adipose tissue has been shown to relax ...
  https://biblio.ugent.be/publication/1245143
*  Homocysteine Upregulates Resistin Production From Adipocytes In Vivo and In Vitro | Diabetes
Primary cultured rat adipocytes express all PKC isoforms except PKC-γ (27). Our results show that in adipocytes, PKCs, most ... Isolation and culture of primary rat adipocytes.. Mature adipocytes were isolated from epididymal fat pads of Sprague-Dawley ... After another 24 h incubation, adipocytes treated with the conditioned medium from Hcy-treated adipocytes showed significant ... adipocytes treated with the conditioned medium from Hcy-treated adipocytes also showed a significant reduction in insulin- ...
  http://diabetes.diabetesjournals.org/content/57/4/817
*  Frontiers | Bacterial Translocation - Impact on the Adipocyte Compartment | Immunology
Adipose tissue comprises not only mature adipocytes but harbors a variety of other cells including adipocyte precursor cells ( ... In vitro, adipocytes release CRP after stimulation with TNFα, IL-6, LPS, and E. coli, but not Pam3Cys (a TLR2 ligand), MDP (a ... Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans. J Lipid Res (2005) 46( ... Adipocyte fetuin-a contributes to macrophage migration into adipose tissue and polarization of macrophages. J Biol Chem (2013) ...
  https://www.frontiersin.org/articles/10.3389/fimmu.2013.00510/full
*  Homocysteine Upregulates Resistin Production From Adipocytes In Vivo and In Vitro | Diabetes
Adipocyte Liver Kinase b1 Suppresses Beige Adipocyte Renaissance Through Class IIa Histone Deacetylase 4 ... Homocysteine Upregulates Resistin Production From Adipocytes In Vivo and In Vitro. Yin Li, Changtao Jiang, Guoheng Xu, Nanping ... Homocysteine Upregulates Resistin Production From Adipocytes In Vivo and In Vitro. Yin Li, Changtao Jiang, Guoheng Xu, Nanping ... 19.27 ± 1.71 ng/ml, P , 0.01). Hcy (300-1000 μmol/l) also increased mRNA expression of resistin in primary rat adipocytes in a ...
  http://diabetes.diabetesjournals.org/content/57/4/817.short?cited-by=yes&legid=diabetes