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*  Ca2 Influx and Tyrosine Kinases Trigger Bordetella Adenylate Cyclase Toxin ACT Endocytosis. Cell Physiology and Expression of...
Ca2 Influx and Tyrosine Kinases Trigger Bordetella Adenylate Cyclase Toxin ACT Endocytosis. Cell Physiology and Expression of ... Ca2 Influx and Tyrosine Kinases Trigger Bordetella Adenylate Cyclase Toxin ACT Endocytosis. Cell Physiology and Expression of ... Ca2 Influx and Tyrosine Kinases Trigger Bordetella Adenylate Cyclase Toxin ACT Endocytosis. Cell Physiology and Expression of ... This pathogenic bacterium produces a unique adenylate cyclase toxin ACT which enters human phagocytes and catalyzes the ...
  http://libros.duhnnae.com/2017/jun8/149829571451-Ca2-Influx-and-Tyrosine-Kinases-Trigger-Bordetella-Adenylate-Cyclase-Toxin-ACT-Endocytosis-Cell-Physiology-and-Expression-of-the-CD11b-CD18-Integrin.php
*  Bordetella adenylate cyclase toxin: the role of cell interaction in toxin functio - Joshua Eby
AC toxin) is necessary for disease caused by Bordetella pertussis, which has reemerged in the United States over the last two ... Bordetella adenylate cyclase toxin: the role of cell interaction in toxin functio Eby, Joshua Clark University of Virginia, ... The toxin molecule is a unique hybrid of an adenylate cyclase enzyme and a binding domain homologous to the repeats-in-toxin ( ... Bordetella adenylate cyclase toxin: the role of cell interaction in toxin functio. Eby, Joshua Clark / University of Virginia. ...
  http://grantome.com/grant/NIH/K08-AI081900-05
*  adenocarcinoma of pituitary gland 2005:2010[pubdate] *count=100 - BioMedLib™ search engine
Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide. Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, ... Chemical-registry-number] 0 / Neuromuscular Agents; EC 3.4.24.69 / Botulinum Toxins, Type A ... Pituitary Adenylate Cyclase-Activating Polypeptide; 0 / Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I; ...
  http://www.bmlsearch.com/?kwr=adenocarcinoma+of+pituitary+gland+2005:2010%5Bpubdate%5D&cxts=100&stmp=b0
*  Pituitary adenylate cyclase-activating polypeptide (PACAP) has neuroprotective function in dopamine-based neurodegeneration...
Following the toxin treatments a significant increase in the MB-COMT level was observed in both models and the increased MB- ... Pituitary adenylate cyclase-activating polypeptide (PACAP) has neuroprotective function in dopamine-based neurodegeneration ... Pituitary adenylate cyclase-activating polypeptide (PACAP) has neuroprotective function in dopamine-based neurodegeneration ... Pituitary adenylate cyclase-activating polypeptide (PACAP) has neuroprotective function in dopamine-based neurodegeneration ...
  http://dmm.biologists.org/content/early/2016/12/14/dmm.027185
*  Bordetella pertussis adenylate cyclase toxin modulates innate and adaptive immune responses: distinct roles for acylation and...
Adenylate cyclase toxin (CyaA) of Bordetella pertussis belongs to the repeat in toxin family of pore-forming toxins, which ... Boyd, A.P., Ross, P.J., Conroy, H., Mahon, N Lavelle, E.C.and Mills, K.H.G. `Bordetella pertussis adenylate cyclase toxin ... Bordetella pertussis adenylate cyclase toxin modulates innate and adaptive immune responses: distinct roles for acylation and ... Bordetella pertussis adenylate cyclase toxin modulates innate and adaptive immune responses - distinct roles for acylation and ...
  http://www.tara.tcd.ie/handle/2262/33228
*  Adenylate cyclase toxin from Bordetella pertussis synergises with lipopolysaccharide to promote innate IL-10 production and...
Ross, P.J., Lavelle, E.C., Mills, K.H.G. and A.P. Boyd `Adenylate cyclase toxin from Bordetella pertussis synergises with ... Adenylate cyclase toxin from Bordetella pertussis synergises with lipopolysaccharide to promote innate IL-10 production and ... Adenylate cyclase toxin (CyaA) from Bordetella pertussis can subvert host immune responses allowing bacterial colonization. ... Adenylate Cyclase Toxin from Bordetella pertussis Synergizes with Lipopolysaccharide To Promote Innate Interleukin-10 ...
  http://www.tara.tcd.ie/handle/2262/33327
*  Ca2+ Influx and Tyrosine Kinases Trigger Bordetella Adenylate Cyclase Toxin (ACT) Endocytosis. Cell Physiology and Expression...
This pathogenic bacterium produces a unique adenylate cyclase toxin (ACT) which enters human phagocytes and catalyzes the ... Ca2+ Influx and Tyrosine Kinases Trigger Bordetella Adenylate Cyclase Toxin (ACT) Endocytosis. Cell Physiology and Expression ... which suggests the mounting of an anti-toxin cell repair-response, very likely involving the toxin elimination from the cell ... into the target cell appear to be common master denominators in the different endocytic strategies activated by this toxin. ...
  https://addi.ehu.es/handle/10810/11378
*  Effects of pertussis toxin on adenylate cyclase responses to prostaglandin E2 and calcitonin in human breast cancer cells |...
Effects of pertussis toxin on adenylate cyclase responses to prostaglandin E2 and calcitonin in human breast cancer cells. V P ... of adenylate cyclase, there was no change in basal or calcitonin-responsive adenylate cyclase in intact cells. However, the ... Effects of pertussis toxin on adenylate cyclase responses to prostaglandin E2 and calcitonin in human breast cancer cells ... Effects of pertussis toxin on adenylate cyclase responses to prostaglandin E2 and calcitonin in human breast cancer cells ...
  http://www.biochemj.org/content/224/2/371
*  Table of Contents - March 13, 2018, 115 (11) | PNAS
Phospholipase A activity of adenylate cyclase toxin? Jiri Masin, Radim Osicka, Ladislav Bumba, and Peter Sebo ...
  http://www.pnas.org/content/115/11
*  Cell proliferation, tumorogenicity, and apoptosis sub-cluster 17
The adenylate cyclase toxins. Ahuja Nidhi - - 2004 Cyclic AMP is a ubiquitous messenger that integrates many processes of the ... The Clostridium botulinum C2 toxin is the prototype of the family of binary actin-ADP-ribosylating toxins. C2 toxin is composed ... Toxin binding to its receptor, guanylyl cyclase C (GC-C), results in receptor activation and the production of high ... Diverse families of adenylate cyclases and phosphodiesterases stringently regulate the intracellular concentration of cAMP. Any ...
  http://www.biomedsearch.com/cluster/2/Cell-proliferation-tumorogenicity-and-apoptosis/sub-17-p7.html
*  ASMscience | The Evolution of Bacteri
Hewlett, E. L.,, L. Gray,, M. Allietta,, I. Ehrmann,, V. M. Gordon, and, M. C. Gray. 1991. Adenylate cyclase toxin from ... Hewlett, E. L.,, V. M. Gordon,, J. D. McCaffery,, W. M. Sutherland, and, M. C. Gray. 1989. Adenylate cyclase toxin from ... Gray, M. C.,, W. Ross,, K. Kim, and, E. L. Hewlett. 1999. Characterization of binding of adenylate cyclase toxin to target ... Hewlett, E. L.,, K. J. Kim,, S. J. Lee, and, M. C. Gray. 2000. Adenylate cyclase toxin from Bordetella pertussis: current ...
  http://www.asmscience.org/content/book/10.1128/9781555815622.ch10
*  Bordetella - Wikipedia
One of the most important of the regulated toxins is adenylate cyclase toxin, which aids in the evasion of innate immunity. The ... Gray MC, Donato GM, Jones FR, Kim T, Hewlett EL (2004). "Newly secreted adenylate cyclase toxin is responsible for intoxication ... Hewlett EL, Donato GM, Gray MC (2006). "Macrophage cytotoxicity produced by adenylate cyclase toxin from Bordetella pertussis: ... Recently discovered activities of adenylate cyclase toxin, including transmembrane pore formation and stimulation of calcium ...
  https://en.wikipedia.org/wiki/Bordetella
*  Free Laboratory Science Flashcards about Unit 3 Chapter 18
filamentous hemagglutinin and pertacin, pertussis toxin, adenylate cyclase toxin, tracheal cytotoxin. Bordetella *epidemiology* ... filamentous hemagglutinin and pertacin, pertussis toxin, adenylate cyclase toxin, tracheal cytotoxin. Bordetella pertussis * ...
  https://www.studystack.com/flashcard-2241823
*  Circular Dichroism to Study Protein Interactions - Current Protocols
Interaction of calcium with Bordetella pertussis adenylate cyclase toxin. J. Biol. Chem. 270:26370‐26376. ...
  http://www.currentprotocols.com/WileyCDA/CPUnit/refId-ps2010.html
*  Merkel TJ[au] - PubMed - NCBI
Use of a Toxin Neutralization Assay To Characterize the Serologic Response to Adenylate Cyclase Toxin after Infection with ... Quantification of the adenylate cyclase toxin of Bordetella pertussis in vitro and during respiratory infection. ... Evaluation of genetically inactivated alpha toxin for protection in multiple mouse models of Staphylococcus aureus infection. ...
  https://www.ncbi.nlm.nih.gov/pubmed?cmd=search&term=Merkel+TJ%5Bau%5D&dispmax=50
*  Cited In for PubMed (Select 11181701) - PubMed - NCBI
Bordetella adenylate cyclase toxin is a unique ligand of the integrin complement receptor 3. ... Chronic opioid treatment augments caveolin-1 scaffolding: relevance to stimulatory μ-opioid receptor adenylyl cyclase signaling ...
  https://www.ncbi.nlm.nih.gov/pubmed?linkname=pubmed_pubmed_citedin&from_uid=11181701
*  Frontiers | Recognition of Extracellular Bacteria by NLRs and Its Role in the Development of Adaptive Immunity | Immunology
These mechanisms include bacterial secretion systems, pore-forming toxins and outer membrane vesicles. We will then focus on ... These mechanisms include bacterial secretion systems, pore-forming toxins and outer membrane vesicles. We will then focus on ... Inflammasome activation by adenylate cyclase toxin directs Th17 responses and protection against Bordetella pertussis. J ... These PFTs include the adenylate cyclase toxin (CyaA) from Bordetella pertussis (20), pneumolysin from Streptococcus pneumoniae ...
  https://www.frontiersin.org/articles/10.3389/fimmu.2013.00344/full
*  Bacillus anthracis-derived edema toxin (ET) counter-regulates movement of neutrophils and macromolecules through the...
Ahuja N, Kumar P, Bhatnagar R: The adenylate cyclase toxins. Crit Rev Microbiol. 2004, 30: 187-196.PubMedCrossRefGoogle Scholar ... PA combines with either LF to form lethal toxin (LT), or with EF to form edema toxin (ET) [1]. LT received its name as it was ... Structural and kinetic analyses of the interaction of anthrax adenylyl cyclase toxin with reaction products cAMP and ... which is an adenyl cyclase, and protective antigen (PA). Since cAMP, a product of adenyl cyclase, is known to enhance ...
  https://rd.springer.com/article/10.1186/1471-2180-12-2
*  Protein Lounge: Glutathione Metabolism in B. pertussis
It produces a complex array of adhesins, aggressins and toxins that are presumed to be important in the colonisation of its ... including Pertussis Toxin, Adenylate Cyclase Toxin, Dermonecrotic Toxin and Tracheal Cytotoxin (Ref.1, 2 & 3).. Glutathione in ... It produces a complex array of adhesins, aggressins and toxins that are presumed to be important in the colonisation of its ... Bordetella pertussis, the etiologic agent of whooping cough, produces numerous toxins ...
  http://www.proteinlounge.com/Pathway/Glutathione%20Metabolism%20in%20B.%20pertussis
*  ESAT-6 Inhibits Production of IFN-γ by Mycobacterium tuberculosis-Responsive Human T Cells | The Journal of Immunology
Suppression of T-lymphocyte activation and chemotaxis by the adenylate cyclase toxin of Bordetella pertussis. Infect. Immun. 76 ... Bordetella pertussis adenylate cyclase toxin inhibits T cell activation and production of IL-12 by dendritic cells through ... p70 in human monocyte-derived dendritic cells blocks IL-12 p35 through adenylate cyclase toxin-dependent cyclic AMP induction. ... Like the toxins produced by B. anthracis and B. pertussis, ESAT-6 affects both T cells and mononuclear phagocytes. In monocytic ...
  http://www.jimmunol.org/content/182/6/3668.long
*  Whooping cough - Wikipedia
"Pertussis toxin and adenylate cyclase toxin: key virulence factors of Bordetella pertussis and cell biology tools". Future ... "cough toxin".[33] Pertussis toxin causes lymphocytosis by an unknown mechanism. The elevated number of white blood cells leads ... The bacteria secrete a number of toxins. Tracheal cytotoxin, a fragment of peptidoglycan, kills ciliated epithelial cells and ... adults and adolescents who have already been infected for several weeks to determine whether antibody against pertussis toxin ...
  https://en.m.wikipedia.org/wiki/Whooping_cough