*  Bordetella adenylate cyclase toxin: the role of cell interaction in toxin functio - Joshua Eby
AC toxin) is necessary for disease caused by Bordetella pertussis, which has reemerged in the United States over the last two ... Bordetella adenylate cyclase toxin: the role of cell interaction in toxin functio Eby, Joshua Clark University of Virginia, ... The toxin molecule is a unique hybrid of an adenylate cyclase enzyme and a binding domain homologous to the repeats-in-toxin ( ... Bordetella adenylate cyclase toxin: the role of cell interaction in toxin functio. Eby, Joshua Clark / University of Virginia. ...
  http://grantome.com/grant/NIH/K08-AI081900-05
*  Adenylate cyclase toxin from Bordetella pertussis synergises with lipopolysaccharide to promote innate IL-10 production and...
Ross, P.J., Lavelle, E.C., Mills, K.H.G. and A.P. Boyd `Adenylate cyclase toxin from Bordetella pertussis synergises with ... Adenylate cyclase toxin from Bordetella pertussis synergises with lipopolysaccharide to promote innate IL-10 production and ... Adenylate cyclase toxin (CyaA) from Bordetella pertussis can subvert host immune responses allowing bacterial colonization. ... Adenylate Cyclase Toxin from Bordetella pertussis Synergizes with Lipopolysaccharide To Promote Innate Interleukin-10 ...
  http://www.tara.tcd.ie/handle/2262/33327
*  Ca2 Influx and Tyrosine Kinases Trigger Bordetella Adenylate Cyclase Toxin ACT Endocytosis. Cell Physiology and Expression of...
Ca2 Influx and Tyrosine Kinases Trigger Bordetella Adenylate Cyclase Toxin ACT Endocytosis. Cell Physiology and Expression of ... Ca2 Influx and Tyrosine Kinases Trigger Bordetella Adenylate Cyclase Toxin ACT Endocytosis. Cell Physiology and Expression of ... Ca2 Influx and Tyrosine Kinases Trigger Bordetella Adenylate Cyclase Toxin ACT Endocytosis. Cell Physiology and Expression of ... This pathogenic bacterium produces a unique adenylate cyclase toxin ACT which enters human phagocytes and catalyzes the ...
  http://libros.duhnnae.com/2017/jun8/149829571451-Ca2-Influx-and-Tyrosine-Kinases-Trigger-Bordetella-Adenylate-Cyclase-Toxin-ACT-Endocytosis-Cell-Physiology-and-Expression-of-the-CD11b-CD18-Integrin.php
*  Effects of pertussis toxin on adenylate cyclase responses to prostaglandin E2 and calcitonin in human breast cancer cells |...
Effects of pertussis toxin on adenylate cyclase responses to prostaglandin E2 and calcitonin in human breast cancer cells. V P ... of adenylate cyclase, there was no change in basal or calcitonin-responsive adenylate cyclase in intact cells. However, the ... Effects of pertussis toxin on adenylate cyclase responses to prostaglandin E2 and calcitonin in human breast cancer cells ... Effects of pertussis toxin on adenylate cyclase responses to prostaglandin E2 and calcitonin in human breast cancer cells ...
  http://www.biochemj.org/content/224/2/371
*  Cell proliferation, tumorogenicity, and apoptosis sub-cluster 17
The adenylate cyclase toxins. Ahuja Nidhi - - 2004 Cyclic AMP is a ubiquitous messenger that integrates many processes of the ... The Clostridium botulinum C2 toxin is the prototype of the family of binary actin-ADP-ribosylating toxins. C2 toxin is composed ... Toxin binding to its receptor, guanylyl cyclase C (GC-C), results in receptor activation and the production of high ... Diverse families of adenylate cyclases and phosphodiesterases stringently regulate the intracellular concentration of cAMP. Any ...
  http://www.biomedsearch.com/cluster/2/Cell-proliferation-tumorogenicity-and-apoptosis/sub-17-p7.html
*  ASMscience | The Evolution of Bacteri
Hewlett, E. L.,, L. Gray,, M. Allietta,, I. Ehrmann,, V. M. Gordon, and, M. C. Gray. 1991. Adenylate cyclase toxin from ... Hewlett, E. L.,, V. M. Gordon,, J. D. McCaffery,, W. M. Sutherland, and, M. C. Gray. 1989. Adenylate cyclase toxin from ... Gray, M. C.,, W. Ross,, K. Kim, and, E. L. Hewlett. 1999. Characterization of binding of adenylate cyclase toxin to target ... Hewlett, E. L.,, K. J. Kim,, S. J. Lee, and, M. C. Gray. 2000. Adenylate cyclase toxin from Bordetella pertussis: current ...
  http://www.asmscience.org/content/book/10.1128/9781555815622.ch10
*  Bordetella - Wikipedia
One of the most important of the regulated toxins is adenylate cyclase toxin, which aids in the evasion of innate immunity. The ... Gray MC, Donato GM, Jones FR, Kim T, Hewlett EL (2004). "Newly secreted adenylate cyclase toxin is responsible for intoxication ... Hewlett EL, Donato GM, Gray MC (2006). "Macrophage cytotoxicity produced by adenylate cyclase toxin from Bordetella pertussis: ... Recently discovered activities of adenylate cyclase toxin, including transmembrane pore formation and stimulation of calcium ...
  https://en.wikipedia.org/wiki/Bordetella
*  Free Laboratory Science Flashcards about Unit 3 Chapter 18
filamentous hemagglutinin and pertacin, pertussis toxin, adenylate cyclase toxin, tracheal cytotoxin. Bordetella *epidemiology* ... filamentous hemagglutinin and pertacin, pertussis toxin, adenylate cyclase toxin, tracheal cytotoxin. Bordetella pertussis * ...
  https://www.studystack.com/flashcard-2241823
*  Circular Dichroism to Study Protein Interactions - Current Protocols
Interaction of calcium with Bordetella pertussis adenylate cyclase toxin. J. Biol. Chem. 270:26370‐26376. ...
  http://www.currentprotocols.com/WileyCDA/CPUnit/refId-ps2010.html
*  Merkel TJ[au] - PubMed - NCBI
Use of a Toxin Neutralization Assay To Characterize the Serologic Response to Adenylate Cyclase Toxin after Infection with ... Quantification of the adenylate cyclase toxin of Bordetella pertussis in vitro and during respiratory infection. ... Evaluation of genetically inactivated alpha toxin for protection in multiple mouse models of Staphylococcus aureus infection. ...
  https://www.ncbi.nlm.nih.gov/pubmed?cmd=search&term=Merkel+TJ%5Bau%5D&dispmax=50
*  Cited In for PubMed (Select 11181701) - PubMed - NCBI
Bordetella adenylate cyclase toxin is a unique ligand of the integrin complement receptor 3. ... Chronic opioid treatment augments caveolin-1 scaffolding: relevance to stimulatory μ-opioid receptor adenylyl cyclase signaling ...
  https://www.ncbi.nlm.nih.gov/pubmed?linkname=pubmed_pubmed_citedin&from_uid=11181701
*  Bacillus anthracis-derived edema toxin (ET) counter-regulates movement of neutrophils and macromolecules through the...
Ahuja N, Kumar P, Bhatnagar R: The adenylate cyclase toxins. Crit Rev Microbiol. 2004, 30: 187-196.PubMedCrossRefGoogle Scholar ... PA combines with either LF to form lethal toxin (LT), or with EF to form edema toxin (ET) [1]. LT received its name as it was ... Structural and kinetic analyses of the interaction of anthrax adenylyl cyclase toxin with reaction products cAMP and ... which is an adenyl cyclase, and protective antigen (PA). Since cAMP, a product of adenyl cyclase, is known to enhance ...
  https://rd.springer.com/article/10.1186/1471-2180-12-2
*  Protein Lounge: Glutathione Metabolism in B. pertussis
It produces a complex array of adhesins, aggressins and toxins that are presumed to be important in the colonisation of its ... including Pertussis Toxin, Adenylate Cyclase Toxin, Dermonecrotic Toxin and Tracheal Cytotoxin (Ref.1, 2 & 3).. Glutathione in ... It produces a complex array of adhesins, aggressins and toxins that are presumed to be important in the colonisation of its ... Bordetella pertussis, the etiologic agent of whooping cough, produces numerous toxins ...
  http://www.proteinlounge.com/Pathway/Glutathione%20Metabolism%20in%20B.%20pertussis
*  RTX toxin - Wikipedia
"Membrane restructuring by Bordetella pertussis adenylate cyclase toxin, a member of the RTX toxin family". Journal of ... Adenylate cyclase toxin (ACT or CyaA), is a primary virulence factor in Bordetella pertussis. CyaA is a multifunctional RTX ... The C-terminal domain of the adenylate cyclase toxin (ACT or CyaA; TC# 1.C.11.1.4) of Bordetella pertussis forms a small cation ... Bumba, Ladislav; Jiri Masin; Radovan Fiser; Peter Sebo (2010). "Bordetella Adenylate Cyclase Toxin Mobilizes Its b2 Integrin ...
  https://en.wikipedia.org/wiki/RTX_toxin
*  ESAT-6 Inhibits Production of IFN-γ by Mycobacterium tuberculosis-Responsive Human T Cells | The Journal of Immunology
Suppression of T-lymphocyte activation and chemotaxis by the adenylate cyclase toxin of Bordetella pertussis. Infect. Immun. 76 ... Bordetella pertussis adenylate cyclase toxin inhibits T cell activation and production of IL-12 by dendritic cells through ... p70 in human monocyte-derived dendritic cells blocks IL-12 p35 through adenylate cyclase toxin-dependent cyclic AMP induction. ... Like the toxins produced by B. anthracis and B. pertussis, ESAT-6 affects both T cells and mononuclear phagocytes. In monocytic ...
  http://www.jimmunol.org/content/182/6/3668.long
*  Pertussis toxin - Wikipedia
Bagley K, Abdelwahab S, Tuskan R, Fouts T, Lewis G (2002). "Pertussis toxin and the adenylate cyclase toxin from Bordetella ... Carbonetti NH (2010). "Pertussis toxin and adenylate cyclase toxin: key virulence factors of Bordetella pertussis and cell ... The Gi subunits remain locked in their GDP-bound, inactive state, thus unable to inhibit adenylate cyclase activity, leading to ... Pertussis toxin is an exotoxin with six subunits (named S1 through S5-each complex contains two copies of S4). The subunits are ...
  https://en.wikipedia.org/wiki/Pertussis_toxin
*  CyaA - Wikipedia
Carbonetti NH, Artamonova GV, Andreasen C, Bushar N (May 2005). "Pertussis toxin and adenylate cyclase toxin provide a one-two ... Ladant D, Ullmann A (April 1999). "Bordatella pertussis adenylate cyclase: a toxin with multiple talents". Trends Microbiol. 7 ... "The adenylate cyclase toxin of Bordetella pertussis binds to target cells via the alpha(M)beta(2) integrin (CD11b/CD18)". J. ... Bifunctional hemolysin/adenylate cyclase is a protein that in B. pertussis (the bacteria that causes whooping cough) is encoded ...
  https://en.wikipedia.org/wiki/CyaA
*  News this Week | Science
New ingredients might include adenylate cyclase toxin, a protein that helps B. pertussis establish an infection. Novartis, of ... including an important substance called pertussis toxin. The two vaccines now used in the United States also contain the ... have developed a live pertussis vaccine in which three of the pertussis toxins have been genetically deactivated or removed. ... whole-cell vaccines proved effective at preventing disease even while producing lower antibody levels to pertussis toxin and ...
  http://science.sciencemag.org/content/341/6145/news-summaries
*  Isolation of Food Pathogens From Freshly Milled Palm Oil and the Effect of Sterilization on Oil Quality Parameters
Ahuja N, Kumar P, Bhatnagar R. (2004). The adenylate cyclase toxins. Crit. Rev. Microbiol. 30: 187-196. ... The bacterium has several virulence factors like extracellular toxins [1] and proteases [31] which adapt to specific host ... Measuring the economic impacts of Fusarium toxins in animal feeds. Anim Feed Sci Technol. 137 (3-4): 363-374. ...
  http://pubs.sciepub.com/jfs/2/2/4/index.html
*  Plus it
Protein kinase A translocation and insulin secretion in pancreatic beta-cells: studies with adenylate cyclase toxin from ...
  http://diabetes.diabetesjournals.org/content/61/3/642
*  Frontiers | Dendritic cell-based vaccination in cancer: therapeutic implications emerging from murine models | Immunology
The adenylate cyclase toxin of Bordetella pertussis binds to target cells via the alpha (M)beta (2) integrin (CD11b/CD18). J ... The candidate vaccine CyaA-Tyr (detoxified adenylate cyclase carrying a HLA-A*02-restricted tyrosinase 369-377 CTL epitope), ...
  https://www.frontiersin.org/articles/10.3389/fimmu.2015.00243/full
*  Try binary options for free
Repeat sequences in the Bordetella pertussis adenylate cyclase toxin can be recognized as alternative carboxy-proximal ...
  http://imbc-med.ru/try-binary-options-for-free-3.html