*  Truncating APC mutations have dominant effects on proliferation, spindle checkpoint control, survival and chromosome stability ...
Germline mutations in the adenomatous polyposis coli (APC) gene are responsible for familial adenomatous polyposis (FAP). In ... Nathke, I. S., Adams, C. L., Polakis, P., Sellin, J. H. and Nelson, W. J. (1996). The adenomatous polyposis coli tumor ... Dikovskaya, D., Newton, I. P. and Nathke, I. S. (2004). The adenomatous polyposis coli protein is required for the formation of ... Zumbrunn, J., Kinoshita, K., Hyman, A. A. and Nathke, I. S. (2001). Binding of the adenomatous polyposis coli protein to ...
  http://jcs.biologists.org/content/117/26/6339?ijkey=5798b1030cffb7bd886a0f58812ba073c713fe64&keytype2=tf_ipsecsha
*  Adenomatous Polyposis Coli; Polyposis Coli, Familial; Polyposis Syndrome, Familial
Polyposis Coli, Familial; Polyposis Syndrome, Familial. On-line free medical diagnosis assistant. Ranked list of possible ... Adenomatous Polyposis Coli (Polyposis Coli, Familial; Polyposis Syndrome, Familial). A polyposis syndrome due to an autosomal ... "Adenomatous Polyposis Coli"Drugs, active principles and "Adenomatous Polyposis Coli"Medicinal plantsQuestions and answers from ... The syndrome is characterized by the development of hundreds of adenomatous polyps in the colon and rectum of affected ...
  http://lookfordiagnosis.com/mesh_info.php?term=Adenomatous+Polyposis+Coli&lang=1
*  APC gene mutations and extraintestinal phenotype of familial adenomatous polyposis. | Gut
BACKGROUND: Familial adenomatous polyposis (FAP) is caused by germline mutation of the adenomatous polyposis coli (APC) gene on ...
  http://gut.bmj.com/content/40/4/521
*  Anti-Rat (Rattus) Adenomatous Polyposis Coli antibody for Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Adenomatous Polyposis Coli antibody for Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)). ... Recommended Adenomatous Polyposis Coli Antibody (supplied by: Log in to see ) Antigen Adenomatous Polyposis Coli (APC) ... anti-Adenomatous Polyposis Coli Antibodies * anti-Rat (Rattus) Adenomatous Polyposis Coli antibody for Immunohistochemistry ( ... Synonyms: GS, DP2, DP3, BTPS2, DP2.5, PPP1R46, Adenomatous polyposis coli protein, Protein APC, Deleted in polyposis 2.5, APC ...
  http://www.antibodies-online.com/wnt-signaling-pathway-10/apc-antibody-1888/rat-ihc-p-5933/
*  Adenomatous polyposis coli (Apc) tumor suppressor gene as a multifunctional gene | SpringerLink
... gene is mutated in familial adenomatous polyposis and in sporadic colorectal tumors. The Apc gene product (APC), basically a ... The adenomatous polyposis coli (Apc) gene is mutated in familial adenomatous polyposis and in sporadic colorectal tumors. The ... adenomatous polyposis coli (Apc) gene β-catenin synapse tumor suppressor Wnt signaling ... Kaplan KB, Burds AA, Swedlow JR, Bekir SS, Sorger PK, Näthke IS (2001) A role for the adenomatous polyposis coli protein in ...
  https://link.springer.com/article/10.1111%2Fj.1447-073x.2005.00106.x
*  A Clinical Trial of COX and EGFR Inhibition in Familial Polyposis Patients - Full Text View - ClinicalTrials.gov
Adenomatous Polyposis Coli Drug: Erlotinib Drug: Sulindac Drug: Placebo A Drug: Placebo B Phase 2 ... Adenomatous Polyposis Coli. Intestinal Neoplasms. Gastrointestinal Neoplasms. Digestive System Neoplasms. Neoplasms by Site. ... Genetic and Rare Diseases Information Center resources: Familial Adenomatous Polyposis MYH-associated Polyposis ... Genetics Home Reference related topics: Familial adenomatous polyposis Drug Information available for: Sulindac Erlotinib ...
  https://clinicaltrials.gov/ct2/show/NCT01187901
*  Histogenesis of human colorectal adenomas and hyperplastic polyps: the role of cell proliferation and crypt fission | Gut
2 One of the earliest mutations in colonic carcinogenesis occurs at the adenomatous polyposis coli (APC) gene.3 ... patients with familial adenomatous polyposis and hereditary non-polyposis colorectal carcinoma were excluded) were obtained ... None the less, a recent study of preneoplastic intestine of human familial adenomatous polyposis (FAP) and multiple intestinal ... not only in the small adenomas of polyposis coli but also in the intervening morphologically normal rectal crypts, supporting ...
  http://gut.bmj.com/content/50/2/212
*  Adenomatous polyposis coli (IPR026836) | InterPro | EMBL-EBI
Adenomatous polyposis coli (IPR026836). Short name: APC Family relationships *Adenomatous polyposis coli (APC) family ( ... Adenomatous polyposis coli (APC) is a tumor suppressor protein that induces the degradation of oncogenic beta-catenin and ... Adenomatous polyposis coli (APC): a multi-functional tumor suppressor gene.. J. Cell. Sci. 120 3327-35 2007 ... Structural basis for the recognition of Asef by adenomatous polyposis coli.. Cell Res. 22 372-86 2012 ...
  http://www.ebi.ac.uk/interpro/entry/IPR026836
*  adenomatous polyposis coli protein
Truncation mutations in the adenomatous polyposis coli protein (APC) are responsible for familial polyposis, a form of ... adenomatous polyposis coli protein. Summary. Summary: A negative regulator of beta-catenin signaling which is mutant in ... adenomatous polyposis coli*apc genes*colorectal neoplasms*trans activators*colonic neoplasms*neoplastic gene expression ... We find that RNAi-mediated depletion of two kMAPs, the adenomatous polyposis coli protein (APC) and its binding partner, EB1, ...
  https://www.labome.org/topics/chemicals/and/proteins/cytoskeletal/adenomatous-polyposis-coli-protein-14404.html
*  Adenomatous Polyposis Coli Protein Summary Report | CureHunter
A negative regulator of beta-catenin signaling which is mutant in ADENOMATOUS POLYPOSIS COLI and GARDNER SYNDROME. ... Adenomatous Polyposis Coli (Familial Adenomatous Polyposis) 01/01/2008 - "The adenomatous polyposis coli gene functions as a ... Adenomatous Polyposis Coli Protein. Subscribe to New Research on Adenomatous Polyposis Coli Protein ... 07/15/1994 - "The adenomatous polyposis coli protein (APC) is mutated in familial adenomatous polyposis patients as well as in ...
  http://www.curehunter.com/public/keywordSummaryD025601-Adenomatous-Polyposis-Coli-Protein.do
*  RCSB PDB - Protein Feature View - Adenomatous polyposis coli protein - P25054 (APC HUMAN)
The PDB archive contains information about experimentally-determined structures of proteins, nucleic acids, and complex assemblies. As a member of the wwPDB, the RCSB PDB curates and annotates PDB data according to agreed upon standards. The RCSB PDB also provides a variety of tools and resources. Users can perform simple and advanced searches based on annotations relating to sequence, structure and function. These molecules are visualized, downloaded, and analyzed by users who range from students to specialized scientists.
  http://www.rcsb.org/pdb/protein/P25054
*  Adenomatous Polyposis Coli ELISA & Assay Kits
Compare and order Adenomatous Polyposis Coli ELISA Kits. View citations, images, detection ranges, sensitivity, prices and more ... adenomatosis polyposis coli , adenomatous polyposis coli protein , multiple intestinal neoplasia , adenomatosis polyposis coli ... Adenomatous Polyposis Coli ELISA Kit. 18 products by 10 suppliers: Abbexa , EIAab , Assay Biotechnology , Cloud-Clone , ... tumor suppressor , deleted in polyposis 2.5 , protein phosphatase 1, regulatory subunit 46 , adenomatous polyposis coli homolog ...
  https://www.antibodies-online.com/wnt-signaling-pathway-10/apc-elisa-kit-743/
*  Adenomatous polyposis coli - Wikipedia
Adenomatous polyposis coli (APC) also known as deleted in polyposis 2.5 (DP2.5) is a protein that in humans is encoded by the ... entry on APC-Associated Polyposis Conditions OMIM entries on APC-Associated Polyposis Conditions Adenomatous Polyposis Coli ... The (Adenomatous Polyposis Coli) APC protein normally builds a "destruction complex" with glycogen synthase kinase 3-alpha and ... Rosenberg MM, Yang F, Giovanni M, Mohn JL, Temburni MK, Jacob MH (June 2008). "Adenomatous polyposis coli plays a key role, in ...
  https://en.wikipedia.org/wiki/Adenomatous_polyposis_coli
*  Neurite outgrowth involves adenomatous polyposis coli protein and β-catenin | Journal of Cell Science
Neurite outgrowth involves adenomatous polyposis coli protein and β-catenin. Violet Votin, W. James Nelson, Angela I. M. Barth ... Neurite outgrowth involves adenomatous polyposis coli protein and β-catenin. Violet Votin, W. James Nelson, Angela I. M. Barth ... Neurite outgrowth involves adenomatous polyposis coli protein and β-catenin. Violet Votin, W. James Nelson, Angela I. M. Barth ... Neurite outgrowth involves adenomatous polyposis coli protein and β-catenin Message Subject (Your Name) has sent you a message ...
  http://jcs.biologists.org/content/118/24/5699
*  Methylation analysis of the adenomatous polyposis coli (APC) gene in cdult T-cell leukemia/lymphoma | Cancer Research
Methylation analysis of the adenomatous polyposis coli (APC) gene in cdult T-cell leukemia/lymphoma. Masahide Matsushita, Yang ... The Adenomatous Polyposis Coli (APC) gene is a tumor suppressor gene which is associated with both familial and sporadic cancer ... Methylation analysis of the adenomatous polyposis coli (APC) gene in cdult T-cell leukemia/lymphoma ... Methylation analysis of the adenomatous polyposis coli (APC) gene in cdult T-cell leukemia/lymphoma ...
  http://cancerres.aacrjournals.org/content/66/8_Supplement/372.5
*  Adenomatous polyposis coli-mediated control of beta-catenin is essential for both chondrogenic and osteogenic differentiation...
Adenomatous polyposis coli (Apc) is a key controller of beta-catenin turnover by down-regulating intracellular levels of beta- ... Adenomatous polyposis coli-mediated control of beta-catenin is essential for both chondrogenic and osteogenic differentiation ...
  https://www.sigmaaldrich.com/catalog/papers/19356224
*  Expression of Adenomatous Polyposis Coli Protein in Reactive Astrocytes in Hippocampus of Kainic Acid-Induced Rat | Springer...
The adenomatous polyposis coli gene (APC) was initially identified through its link to colon cancer. It is associated with the ... Adenomatous polyposis coli Astrocytes Oligodendrocytes GSK-3beta Beta-catenin Kainic acid This is a preview of subscription ... The adenomatous polyposis coli gene (APC) was initially identified through its link to colon cancer. It is associated with the ... Expression of Adenomatous Polyposis Coli Protein in Reactive Astrocytes in Hippocampus of Kainic Acid-Induced Rat. ...
  https://rd.springer.com/article/10.1007/s11064-009-0036-3
*  Two Novel Somatic Mutations in Exon 15 of the Adenomatous Polyposis Coli Gene in Iranian Familial Adenomatousis Polyposis Coli...
The Adenomatous Polyposis Coli (APC) gene is considered as a gatekeeper in colorectal tumorigenesis. 60% of somatic mutations ... adenomatous polyposis coli) gene. Hum Mutat 2: 425-434.. *Polakis P (1997) The adenomatous polyposis coli (APC) tumor ... Two Novel Somatic Mutations in Exon 15 of the Adenomatous Polyposis Coli Gene in Iranian Familial Adenomatousis Polyposis Coli ... Two Novel Somatic Mutations in Exon 15 of the Adenomatous Polyposis Coli Gene in Iranian Familial Adenomatousis Polyposis Coli ...
  https://www.omicsonline.org/open-access/two-novel-somatic-mutations-in-exon-15-of-the-adenomatous-polyposiscoli-gene-in-iranian-familial-adenomatousis-polyposis-coli-pati-2161-1041-1000157.php?aid=68007
*  Adenomatous Polyposis Coli Tumor Suppressor Protein Has Signaling Activity in Xenopus laevis Embryos Resulting in the Induction...
The adenomatous polyposis coli (APC)1 gene is a tumor suppressor gene linked to familial adenomatous polyposis (FAP) and to the ... adenomatous polyposis coli. hAPC. human APC. XAPC. Xenopus APC cDNA. XAPC FL. full-length Xenopus APC cDNA. Dlg. Drosophila ... 1991) Identification and characterization of the Familial Adenomatous Polyposis Coli gene. Cell 66:589-600, pmid:1651174.. ... Mutations in the adenomatous polyposis coli (APC) tumor suppressor gene are linked to both familial and sporadic human colon ...
  http://jcb.rupress.org/content/136/2/411
*  Oncogenic mutations in adenomatous polyposis coli (Apc) activate mechanistic target of rapamycin complex 1 (mTORC1)in mice and...
Oncogenic mutations in adenomatous polyposis coli (Apc) activate mechanistic target of rapamycin complex 1 (mTORC1)in mice and ... Truncating mutations in adenomatous polyposis coli (Apc) are strongly linked to colorectal cancers. APC is a negative regulator ... Oncogenic mutations in adenomatous polyposis coli (Apc) activate mechanistic target of rapamycin complex 1 (mTORC1)in mice and ... Oncogenic mutations in adenomatous polyposis coli (Apc) activate mechanistic target of rapamycin complex 1 (mTORC1)in mice and ...
  http://dmm.biologists.org/content/early/2013/11/07/dmm.012625
*  Exploring Novel Properties of Adenomatous Polyposis Coli: Msi1-Knockout Mice Display Alterations in APC and Intestinal Cell...
Adenomatous polyposis coli (APC) is the initiating mutation in 80% of all colorectal cancers. Our lab is focused on ... Exploring Novel Properties of Adenomatous Polyposis Coli: Msi1-Knockout Mice Display Alterations in APC and Intestinal Cell ...
  https://kuscholarworks.ku.edu/handle/1808/9788
*  Relationship between the role of the adenomatous polyposis coli protein in colon cancer and its contribution to cytoskeletal...
A unique feature of colon cancer is that truncation mutations in the APC (adenomatous polyposis coli) gene are common to most ... Abbreviations: APC, adenomatous polyposis coli; Asef, APC-stimulated guanine nucleotide exchange factor; GSK3β, glycogen ... Relationship between the role of the adenomatous polyposis coli protein in colon cancer and its contribution to cytoskeletal ... Relationship between the role of the adenomatous polyposis coli protein in colon cancer and its contribution to cytoskeletal ...
  http://www.biochemsoctrans.org/content/33/4/694
*  The adenomatous polyposis coli gene of the mouse in development and neoplasia.
The adenomatous polyposis coli gene of the mouse in development and neoplasia. Dove, W F 관련메뉴. ; Luongo, C 관련메뉴. ; Connelly, C ...
  http://www.ndsl.kr/ndsl/search/detail/article/articleSearchResultDetail.do?cn=NART00103517
*  Cancer Stem Cells
More than 80% of intestinal neoplasia is associated with the adenomatous polyposis coli (APC) mutation. Doublecortin-like ...
  https://www.biomedcentral.com/collections/cancerstemcells