ampd2, adenosine monophosphate deaminase 2 - Creative Biogene
AMP deaminase 2; AMPD isoform L; adenosine monophosphate deaminase 2 isoform L; AMP deaminase isoform L; AMPD 2; AMPD2_HUMAN; ... Adenosine monophosphate deaminase-2 (EC 220.127.116.11) catalyzes the deamination of AMP to IMP and plays an important role in the ... AMPD2; adenosine monophosphate deaminase 2; adenosine monophosphate deaminase 2 (isoform L); ...https://www.creative-biogene.com/symbolsearch_ampd2.html
Myoadenylate deaminase deficiency does not affect muscle anaplerosis during exhaustive exercise in humans - Tarnopolsky - 2001 ...
Hisatome, I., Morisake, T., Kamma, H., Sugama, T., Morisaki, H., Ohtahara, A. & Holmes, E. W. (1998). Control of AMP deaminase ... Sinkeler S. P., Binkhorst, R. A., Joosten, E. M., Wevers, R. A., Coerwinkei, M. M. & Oei, T. L. (1987). AMP deaminase ... Morisaki, T., Gross, M., Morisaki, H., Pongratz, D., Zollner, N. & Holmes, E. W. (1992). Molecular basis of AMP deaminase ... Norman, B., Mahnke-Zizelman, D. K., Vallis, A. & Sabina, R. L. (1998). Genetic and other determinants of AMP deaminase activity ...http://onlinelibrary.wiley.com/doi/10.1111/j.1469-7793.2001.t01-1-00881.x/full
Abstract 19495: Cardioprotective Effect of AMP Deaminase Inhibition in Oxygen Deprivation | Circulation
Abstract 19495: Cardioprotective Effect of AMP Deaminase Inhibition in Oxygen Deprivation. Ryszard T Smolenski, Tomasz ... Studies on the effect of genetic polymorphisms known to affect AMP deaminase (AMPD) activity on progress of heart disease are ... Abstract 19495: Cardioprotective Effect of AMP Deaminase Inhibition in Oxygen Deprivation. Ryszard T Smolenski, Tomasz ... Abstract 19495: Cardioprotective Effect of AMP Deaminase Inhibition in Oxygen Deprivation. Ryszard T Smolenski, Tomasz ...http://circ.ahajournals.org/content/122/Suppl_21/A19495
Regulation of skeletal-muscle AMP deaminase: involvement of histidine residues in the pH-dependent inhibition of the rabbit...
Reaction of rabbit skeletal-muscle AMP deaminase with a low molar excess of diethyl pyrocarbonate results in conversion of the ... Regulation of skeletal-muscle AMP deaminase: involvement of histidine residues in the pH-dependent inhibition of the rabbit ... Regulation of skeletal-muscle AMP deaminase: involvement of histidine residues in the pH-dependent inhibition of the rabbit ... Regulation of skeletal-muscle AMP deaminase: involvement of histidine residues in the pH-dependent inhibition of the rabbit ...http://www.biochemj.org/content/309/3/845
Adenosine monophosphate deaminase deficiency
AMP deaminase 3. Tchem. Enzyme. AMP deaminase 1. Tchem. Enzyme. Name. Description. ...https://pharos.nih.gov/idg/diseases/umls:C2931781
Adenosine monophosphate deaminase deficiency type 1 - Wikipedia
The genetic form is caused by a defect in the gene for AMP deaminase though there is also an acquired form of AMP deficiency. ... AMP is normally converted into IMP by myoadenylate deaminase-so myoadenylate deaminase deficiency reduces energy that would be ... AMP deaminase is an enzyme that converts adenosine monophosphate (AMP) to inosine monophosphate (IMP), freeing an ammonia ... Fischer, H.; Esbjornsson, M.; Sabina, R. L.; Stromberg, A.; Peyrard-Janvid, M.; Norman, B. (2007). "AMP deaminase deficiency is ...https://en.wikipedia.org/wiki/Adenosine_monophosphate_deaminase_deficiency_type_1
AMP deaminase (IPR006329) | InterPro | EMBL-EBI
Expression patterns of AMP-deaminase isozymes in human hepatocellular carcinoma (HCC).. Mol. Cell. Biochem. null null 2008 ... AMP-deaminase (AMPD) is a large, well-conserved eukaryotic protein that catalyzes the hydrolytic deamination of adensosine ... In mammalian liver, the reaction catalysed by AMP-deaminase constitutes a rate-limiting step in adenine nucleotide catabolism [ ... monophosphate (AMP) to inosine monophosphate (IMP), and so plays an important role in purine metabolism. ...http://www.ebi.ac.uk/interpro/entry/IPR006329
AMP deaminase - Wikipedia
AMP deaminase 1 is an enzyme that in humans is encoded by the AMPD1 gene. Adenosine monophosphate deaminase is an enzyme that ... by directly inhibiting AMP deaminase, thereby increasing cellular AMP. It has been shown that in environments with high ... "Metformin activates AMP kinase through inhibition of AMP deaminase". J. Biol. Chem. 286 (1): 1-11. doi:10.1074/jbc.M110.121806 ... 1998). "Control of AMP deaminase 1 binding to myosin heavy chain". Am. J. Physiol. 275 (3 Pt 1): C870-81. PMID 9730972. Sims B ...https://en.wikipedia.org/wiki/AMP_deaminase
AMP deaminase 2 - Wikipedia
AMP deaminase 2 is an enzyme that in humans is encoded by the AMPD2 gene. GRCh38: Ensembl release 89: ENSG00000116337 - Ensembl ... Bausch-Jurken MT, Mahnke-Zizelman DK, Morisaki T, Sabina RL (1992). "Molecular cloning of AMP deaminase isoform L. Sequence and ... Van den Bergh F, Sabina RL (1996). "Characterization of human AMP deaminase 2 (AMPD2) gene expression reveals alternative ... "Cloning of human AMP deaminase isoform E cDNAs. Evidence for a third AMPD gene exhibiting alternatively spliced 5'-exons". J ...https://en.wikipedia.org/wiki/AMP_deaminase_2
Variation in the Gene for Muscle-Specific AMP Deaminase Is Associated With Insulin Clearance, a Highly Heritable Trait |...
By converting AMP to inosine monophosphate, AMPD1 plays a major role in regulating cellular AMP levels; AMP activates AMP ... codes for the muscle-specific form of the AMP deaminase enzyme (myoadenylate deaminase), which catalyzes the deamination of AMP ... We tested the candidate gene AMP deaminase 1 (AMPD1) for association with insulin-related traits because it codes for an enzyme ... Morisaki T, Gross M, Morisaki H, Pongratz D, Zollner N, Holmes EW: Molecular basis of AMP deaminase deficiency in skeletal ...http://diabetes.diabetesjournals.org/content/54/4/1222
Nucleic acid metabolism - Wikipedia
XMP is then converted into GMP by using the hydrolysis of 1 ATP and the conversion of glutamine to glutamate. AMP and GMP ... Guanine is then deaminated via guanine deaminase to form xanthine which is then converted to uric acid. Oxygen is the final ... While IMP can be directly converted to AMP, synthesis of GMP (guanosine monophosphate) requires an intermediate step, in which ... The nucleoside, adenosine, is then deaminated and hydrolyzed to form hypoxanthine via adenosine deaminase and nucleosidase ...https://en.wikipedia.org/wiki/Nucleic_acid_metabolism
Nucleotide salvage - Wikipedia
The nucleosides cytidine and deoxycytidine can be salvaged along the uracil pathway by cytidine deaminase, which converts them ... AMP Folate biosynthesis. Tetrahydrofolic acid and its derivatives are produced by salvage pathways from GTP. ...https://en.wikipedia.org/wiki/Nucleotide_salvage
Search: All Pfam signatures | InterPro | EMBL-EBI
Adenosine/AMP deaminase domain (IPR001365) Pfam signature: PF00962 Cellulosome anchoring protein, cohesin domain (IPR002102) ... Porphobilinogen deaminase, N-terminal (IPR022417) Pfam signature: PF01379 Sugar isomerase (SIS) (IPR001347) Pfam signature: ... AMP-dependent synthetase/ligase (IPR000873) Pfam signature: PF00501 Phycobilisome, alpha/beta subunit (IPR012128) Pfam ... Cytidine and deoxycytidylate deaminase domain (IPR002125) Pfam signature: PF00383 Molybdopterin oxidoreductase (IPR006656) Pfam ...http://www.ebi.ac.uk/interpro/member-database/Pfam
Substituted oxetanes, method of making, and method of use thereof - Patent # 7687500 - PatentGenius
Bookser, Brett C., et al; AMP Deaminase Inhibitors. 2. Initial Dicovery of a Non-Nucleotide Transition-State Inhibitor Series; ... Bookser, Brett C., et al; AMP Deaminase Inhibitors. 4. Further N3-Substituted Coformycin Aglycon Analogues: N3-Alkylmalonates ... Kasibhatla, Srinivas Rao, et al; "AMP Deaminase Inhibitors. 3. SAR of 3-(Carboxyarylalkyl)coformycin Aglycon Analogues"; J. Med ... Terasaka, Tadashi, et al; "A Highly Potent Non-Nucleoside Adenosine Deaminase Inhibitor: Efficient Drug Discovery by ...http://www.patentgenius.com/patent/7687500.html
AMP deaminase; AICAside, aminoimidazole carboxamidoribonucleoside; ADA, adenosine deaminase; AK, adenosine kinase; RFC1, ... Because AICAR inhibits AMP deaminase and AICAR's dephosphorylated metabolite AICARiboside directly inhibits adenosine deaminase ... adenosine deaminase and 5′-adenylate deaminase by polyglutamates of methotrexate and oxidized folates and by 5-aminoimidazole-4 ... AICAR accumulation could lead to the release of AMP (which may be dephosphorylated to adenosine) and/or adenosine (Barankiewicz ...http://pharmrev.aspetjournals.org/content/57/2/163
ADA Gene - GeneCards | ADA Protein | ADA Antibody
Adenosine Deaminase, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards - The Human Gene ... Adenosine and AMP deaminases family.. Family:. * Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP ... two well known members of this group are adenosine deaminase and cytidine deaminase. ... adenosine deaminase,adenine nucleotide catalytic pathway,including a locus control region LCR-ADA (see symbol) in intron 1 *ADA ...https://www.genecards.org/cgi-bin/carddisp.pl?gene=ADA
Gene profile analysis of osteoblast genes differentially regulated by histone deacetylase inhibitors | Springer for Research &...
AMP deaminase 3. 4.177. 1.93E-06. Musculoskeletal, embryonic nuclear protein 1 ...https://rd.springer.com/article/10.1186/1471-2164-8-362
Genome sequence of the insect pathogenic fungus Cordyceps militaris, a valued traditional chinese medicine | Genome Biology |...
... adenine deaminase; ADEK, adenylate kinase; ADK, adenosine kinase; ADN, adenosine nucleosidase; AMPD, AMP deaminase; APRT, ... Abbreviations for different enzymes: ADA, adenosine deaminase; ADE, ...https://genomebiology.biomedcentral.com/articles/10.1186/gb-2011-12-11-r116
AMP deaminase.. EC 18.104.22.168 Profiles. 1psg430_22.214.171.124 (PRI002700). 12psg430_126.96.36.199 (PRI008635). ...http://priam.prabi.fr/cgi-bin/PRIAM_profiles_CurrentRelease.pl?EC=188.8.131.52
AMPD3 Gene - GeneCards | AMPD3 Protein | AMPD3 Antibody
Adenosine Monophosphate Deaminase 3, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards ... AMP + H(2)O = IMP + NH(3). *AMPD3_HUMAN,Q01432. UniProtKB/Swiss-Prot Function: AMP deaminase plays a critical role in energy ... GO annotations related to this gene include deaminase activity and AMP deaminase activity. An important paralog of this gene is ... Cloning of human AMP deaminase isoform E cDNAs. Evidence for a third AMPD gene exhibiting alternatively spliced 5'-exons. (PMID ...http://www.genecards.org/cgi-bin/carddisp.pl?id_type=entrezgene&id=272
Fast skeletal muscle transcriptome of the Gilthead sea bream (Sparus aurata) determined by next generation sequencing | BMC...
Dzeja P, Terzic A: Adenylate kinase and AMP signalling networks: metabolic monitoring, signal communication and body energy ... parvalbumin and adenosine monophosphate deaminase-1 (Additional file 15). Pairwise comparisons of the number of reads that ... AMP-activated protein kinase catalytic subunit alpha/beta/gamma; AKT2, Rac-beta serine/threonine protein kinase 2; AKT3, Rac- ...https://bmcgenomics.biomedcentral.com/articles/10.1186/1471-2164-13-181
Human Metabolome Database: Showing metabocard for Inosinic acid (HMDB0000175)
1. AMP deaminase 1. General function:. Involved in deaminase activity. Specific function:. AMP deaminase plays a critical role ... Exercise causes branched-chain oxoacid dehydrogenase dephosphorylation but not AMP deaminase binding. J Appl Physiol (1985). ... Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity). Gene Name:. ADSSL1. Uniprot ID:. Q8N142 ... It is formed by the deamination of AMP and when hydrolysed produces inosine. Inosinic acid is the ribonucleotide of ...http://www.hmdb.ca/metabolites/HMDB00175