*  20alpha-hydroxysteroid dehydrogenase - Wikipedia
20alpha-dihydroxypregn-4-en-3-one, NAD+, and NADP+, whereas its 4 products are 17-alpha-hydroxyprogesterone, NADH, NADPH, and ... Other names in common use include 20alpha-hydroxy steroid dehydrogenase, 20alpha-hydroxy steroid dehydrogenase, 20alpha-HSD, ... "Expression of 17beta-hydroxysteroid dehydrogenase type 1 and type 2, P450 aromatase, and 20alpha-hydroxysteroid dehydrogenase ... Hershkovitz L, Beuschlein F, Klammer S, Krup M, Weinstein Y (March 2007). "Adrenal 20alpha-hydroxysteroid dehydrogenase in the ...
  https://en.wikipedia.org/wiki/20alpha-hydroxysteroid_dehydrogenase
*  3beta(or 20alpha)-hydroxysteroid dehydrogenase - Wikipedia
... hydroxysteroid dehydrogenase (EC 1.1.1.210) is an enzyme that catalyzes the chemical reaction 5α-androstan-3β,17β-diol + NADP+ ... H+ This enzyme possesses the combined activities of the 3-β-hydroxysteroid dehydrogenase/Δ-5-4 isomerase and 20-α- ... hydroxysteroid dehydrogenase enzymes. Sharaf MA, Sweet F (September 1982). "Dual activity at an enzyme active site: 3 beta,20 ... alpha-hydroxysteroid oxidoreductase from fetal blood". Biochemistry. 21 (19): 4615-20. doi:10.1021/bi00262a016. PMID 6958329. ...
  https://en.wikipedia.org/wiki/3beta(or_20alpha)-hydroxysteroid_dehydrogenase
*  HSD17B1 antibody [EP1682Y] Recombinant (ab51045) | Abcam
Hydroxysteroid (17 beta) dehydrogenase 1 antibody. *MGC13814 antibody. *Placental 17 beta hydroxysteroid dehydrogenase antibody ... Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. ... PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific ...
  http://www.abcam.com/hsd17b1-antibody-ep1682y-ab51045.html
*  KEGG BRITE: KEGG Orthology (KO) - Mus musculus (mouse)
... corticosteroid 11-beta-dehydrogenase isozyme 2 [EC:1.1.1.-] K05295 E1.1.1.149; 20alpha-hydroxysteroid dehydrogenase [EC:1.1. ... 3-oxo-5-alpha-steroid 4-dehydrogenase 2 [EC:1.3.1.22] K12345 SRD5A3; 3-oxo-5-alpha-steroid 4-dehydrogenase 3 [EC:1.3.1.22 1.3. ... dehydrogenase 1 15486 Hsd17b2; hydroxysteroid (17-beta) dehydrogenase 2 27400 Hsd17b6; hydroxysteroid (17-beta) dehydrogenase 6 ... 15483 Hsd11b1; hydroxysteroid 11-beta dehydrogenase 1 15484 Hsd11b2; hydroxysteroid 11-beta dehydrogenase 2 105349 Akr1c18; ...
  http://www.genome.jp/kegg-bin/get_htext?mmu00001+394435
*  Frasor J[au] - PubMed - NCBI
Response-specific and ligand dose-dependent modulation of estrogen receptor (ER) alpha activity by ERbeta in the uterus. ... Impact of estrogen receptor beta on gene networks regulated by estrogen receptor alpha in breast cancer cells. ... Transcriptional profiling of estrogen-regulated gene expression via estrogen receptor (ER) alpha or ERbeta in human ... 20.. PHLDA1 expression is controlled by an estrogen receptor-NFκB-miR-181 regulatory loop and is essential for formation of ER+ ...
  https://www.ncbi.nlm.nih.gov/pubmed?cmd=search&term=Frasor+J%5Bau%5D&dispmax=50
*  KAKEN - Research Projects | Development of new in vivo systems for the evaluation of growth factors function. (KAKENHI-PROJECT...
... hydroxysteroid dehydrogenase.' Biochemca et Biophysica Acta. 1079. 112-118 (1991). *. Description. 「研究成果報告書概要(欧文)」より ... Growth Factors / Cytokine / Activin / Transforming Growth Factor-beta / Nerve growth factor / Tumor Necrosis Factor-alpha / ... hydroxysteroid dehydrogenase in luteotrophic and luteolytic processes during rat pseudopregnancy.' Journal of Reproduction and ... and alpha- subunits in the early embryos and oviducts of different strains of mice.' Journal of Reproduction and Development.38 ...
  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-01860040/
*  Recombinant Human AKR1C1, His-tagged AKR1C1-27157TH - Creative BioMart
3-alpha)-hydroxysteroid dehydrogenase); DDH1; aldo-keto reductase family 1 member C1; DD1; DDH; HAKRC; MBAB;. ... 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity; aldo-keto reductase (NADP) activity; androsterone ... AKR1C1 aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase ... AKR1C1; aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha ( ...
  https://www.creativebiomart.net/description_61505_7.htm
*  AKR1C1 Pre-design Chimera RNAi - (H00001645-R01) - Products - Abnova
3-alpha)-hydroxysteroid dehydrogenase) (AKR1C1), mRNA. (H00001645-R01) - Products - Abnova ... dihydrodiol dehydrogenase 1,dihydrodiol dehydrogenase isoform DD1,hepatic dihydrodiol dehydrogenase,trans- ... 2-ALPHA-HSD,20-ALPHA-HSD,C9,DD1,DDH,DDH1,H-37,HAKRC,MBAB,MGC8954 ... Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ... Homo sapiens aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid ...
  http://www.abnova.com/products/products_detail.asp?catalog_id=H00001645-R01
*  Efficacy and Safety Assessment of T2345 in Ocular Hypertensive or Glaucomatous Patients
... prostaglandin F2-alpha (FP receptors), and prostacyclin (IP receptors). ... Aldo-keto reductase that functions as a bi-directional 17 BETA, 20 ALPHA-HYDROXYSTEROID DEHYDROGENASE. It catalyzes the ...
  https://www.bioportfolio.com/resources/trial/63209/Efficacy-and-Safety-Assessment-of-T2345-in-Ocular-Hypertensive-or-Glaucomatous-Patients.html
*  Recombinant human HSD3a protein (ab109831) | Abcam
3 alpha HSD1. *3-alpha-HSD1. *3-alpha-hydroxysteroid dehydrogenase type I ... 5-alpha-androstan-3-alpha,17-beta-diol (3-alpha-diol). Also has some 20-alpha-hydroxysteroid dehydrogenase activity. The ... Store at -20°C or -80°C. Avoid freeze / thaw cycle.. Preservative: None. Constituents: 20% Glycerol, 0.58% Sodium chloride, ...
  https://www.abcam.com/recombinant-human-hsd3a-protein-ab109831.html
*  AKR1C4 Gene - GeneCards | AK1C4 Protein | AK1C4 Antibody
Chlordecone Reductase; 3-Alpha Hydroxysteroid Dehydrogenase, Type I; Dihydrodiol Dehydrogenase 4 2 3 ... Close kinship of human 20alpha-hydroxysteroid dehydrogenase gene with three aldo-keto reductase genes. (PMID: 10672042) ... aldo-keto reductase family 1,member C4 (3-alpha hydroxysteroid dehydrogenase,type I),with high affinity for dihydrotestosterone ... Molecular cloning of two human liver 3 alpha- hydroxysteroid/dihydrodiol dehydrogenase isoenzymes that are identical with ...
  http://www.genecards.org/cgi-bin/carddisp.pl?gene=AKR1C4
*  Mechanisms in Interleukin 3 Regulated Growth and Differentiation | SpringerLink
Regulation of T cell differentiation: In vitro induction of 20 alpha hydroxysteroid dehydrogenase in splenic lymphocytes is ... Interleukin 2 and 3 regulate the in vitro proliferation of two distinguishable populations of 20 alpha hydroxysteroid ... dehydrogenase positive cells. J. Immunol. 135:1864, (1985).Google Scholar. *. 13.. J. N. Ihle, J. Keller, A. Rein, J. Cleveland ...
  https://link.springer.com/chapter/10.1007/978-1-4684-5323-2_15
*  Human Metabolome Database: Showing metabocard for 7a-Hydroxy-5b-cholestan-3-one (HMDB0006892)
The bile acid intermediates 7-alpha,12-alpha-dihydroxy-4-cholesten-3-one and 7-alpha-hydroxy-4-cholesten-3-one can also act as ... 2. 3-oxo-5-beta-steroid 4-dehydrogenase. General function:. Involved in oxidoreductase activity. Specific function:. ... 5-alpha-androstan-3-alpha,17-beta-diol (3-alpha-diol). Also has some 20-alpha-hydroxysteroid dehydrogenase activity. The ... Efficiently catalyzes the reduction of progesterone, androstenedione, 17-alpha-hydroxyprogesterone and testosterone to 5-beta- ...
  http://www.hmdb.ca/metabolites/HMDB0006892
*  3α-Hydroxysteroid dehydrogenase - Wikipedia
3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)". Rizner TL, Lin HK, Peehl DM, Steckelbroeck S, ... "Close kinship of human 20alpha-hydroxysteroid dehydrogenase gene with three aldo-keto reductase genes". Genes to Cells. 5 (2): ... Khanna M, Qin KN, Cheng KC (June 1995). "Distribution of 3 alpha-hydroxysteroid dehydrogenase in rat brain and molecular ... Dufort I, Labrie F, Luu-The V (February 2001). "Human types 1 and 3 3 alpha-hydroxysteroid dehydrogenases: differential ...
  https://en.wikipedia.org/wiki/3%CE%B1-Hydroxysteroid_dehydrogenase
*  Cloxazolam - Wikipedia
... alpha-hydroxysteroid dehydrogenase for neurosteroids and its inhibition by benzodiazepines" (pdf). Biol Pharm Bull. 25 (4): 441 ... Usami N; Yamamoto T; Shintani S; Ishikura S; Higaki Y; Katagiri Y; Hara A. (Apr 2002). "Substrate specificity of human 3(20) ...
  https://en.wikipedia.org/wiki/Cloxazolam
*  AKR1C1 - Wikipedia
Khanna M, Qin KN, Cheng KC (Jun 1995). "Distribution of 3 alpha-hydroxysteroid dehydrogenase in rat brain and molecular cloning ... Couture JF, Legrand P, Cantin L, Luu-The V, Labrie F, Breton R (Aug 2003). "Human 20alpha-hydroxysteroid dehydrogenase: ... Zhang Y, Dufort I, Rheault P, Luu-The V (Oct 2000). "Characterization of a human 20alpha-hydroxysteroid dehydrogenase". Journal ... 3-alpha)-hydroxysteroid dehydrogenase)". Human AKR1C1 genome location and AKR1C1 gene details page in the UCSC Genome Browser. ...
  https://en.wikipedia.org/wiki/AKR1C1
*  Plus it
The SNP rs11648233 resides in the 17-beta-hydroxysteroid dehydrogenase II gene (HSD17B2), which functions in the pathway that ... Expression cloning and characterization of human 17 beta-hydroxysteroid dehydrogenase type 2, a microsomal enzyme possessing 20 ... alpha-hydroxysteroid dehydrogenase activity. J Biol Chem 1993;268:12964-9. ... of 20% and a per-allele effect size of 1.5 based on a genome-wide significance level of P = 5.0 × 10−8 (ref. 47; Fig. 3A, pink ...
  http://cancerdiscovery.aacrjournals.org/content/4/2/155
*  AKR1C3 - Wikipedia
"Entrez Gene: AKR1C3 aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)". Tian Y, Zhao L, ... "Close kinship of human 20alpha-hydroxysteroid dehydrogenase gene with three aldo-keto reductase genes". Genes to Cells. 5 (2): ... Khanna M, Qin KN, Cheng KC (Jun 1995). "Distribution of 3 alpha-hydroxysteroid dehydrogenase in rat brain and molecular cloning ... Bennett MJ, Schlegel BP, Jez JM, Penning TM, Lewis M (Aug 1996). "Structure of 3 alpha-hydroxysteroid/dihydrodiol dehydrogenase ...
  https://en.wikipedia.org/wiki/AKR1C3
*  Combination Antiretroviral Drug Regimens and Maternal and Neonatal Outcomes | General Principles Regarding Use of...
Low prolactin and high 20-alpha-hydroxysteroid dehydrogenase levels contribute to lower progesterone levels in HIV-infected ... that pregnant women with HIV exposed to PI-based ART with low serum progesterone have elevated levels of human placental 20-α- ... hydroxysteroid dehydrogenase levels, an enzyme that inactivates serum progesterone. These women were also noted to have lower ... 2006;20(18):2345-2353. Available at http://www.ncbi.nlm.nih.gov/pubmed/17117021. ...
  https://aidsinfo.nih.gov/guidelines/html/3/perinatal/171/combination-antiretroviral-drug-regimens-and-pregnancy-outcome
*  John Weisz | Harvard Catalyst Profiles | Harvard Catalyst
Orth J, Weisz J. Development of delta 5 -3 beta hydroxysteroid dehydrogenase and glucose-6-phosphate dehydrogenase activity in ... Hersey RM, Lloyd T, MacLusky NJ, Weisz J. The catechol estrogen, 2-hydroxyestradiol-17 alpha, is formed from estradiol-17 alpha ... Effects of prolactin and LH on the activity of delta5-3beta hydroxy-steroid dehydrogenase, dihydro-orotic dehydrogenase, b- ... A quantitative cytochemical study of glucose-6-phosphate dehydrogenase and delta 5-3 beta-hydroxysteroid dehydrogenase activity ...
  https://connects.catalyst.harvard.edu/profiles/display/Person/77736
*  Interleuchina 3 - Wikipedia
Stomski FC, Sun Q, Bagley CJ, et al., Human interleukin-3 (IL-3) induces disulfide-linked IL-3 receptor alpha- and beta-chain ... Egli trovò un fattore derivato dalla cellula T che induceva la sintesi di 20alpha-idrossisteroido-deidrogenasi in cellule ... induces disulfide-linked IL-3 receptor alpha- and beta-chain heterodimerization, which is required for receptor activation but ... Ihle JN, Pepersack L, Rebar L, Regulation of T cell differentiation: in vitro induction of 20 alpha-hydroxysteroid ...
  https://it.wikipedia.org/wiki/Interleuchina_3
*  Neurosteroid - Wikipedia
... alpha-hydroxysteroid dehydrogenase for neurosteroids and its inhibition by benzodiazepines" (pdf). Biological & Pharmaceutical ... while 3β-hydroxysteroid dehydrogenase and hydroxysteroid sulfotransferases are involved in excitatory neurosteroid production. ... 5α-reductase type I and 3α-hydroxysteroid dehydrogenase are involved in the biosynthesis of inhibitory neurosteroids, ... Melcangi RC, Celotti F, Martini L (March 1994). "Progesterone 5-alpha-reduction in neuronal and in different types of glial ...
  https://en.wikipedia.org/wiki/Neurosteroid
*  Progesterone (17OHP) for Prolongation of Pregnancy in Women With Preterm Rupture of the Membranes (PROM)
5-alpha-dihydroprogesterone. A biologically active 5-alpha-reduced metabolite of plasma PROGESTERONE. It is the immediate ... 17-alpha-hydroxy-progesterone caproate, Castor Oil (Placebo). Location. Desert Good Samaritan Hospital. Mesa. Arizona. United ... Treatment of Preterm Labor With 17 Alpha-Hydroxyprogesterone Caproate. The goal of our research will be to determine the ... It is not known whether 17-alpha-hydroxyprogesterone caproate (17OHP-C) is effective for preventing preterm delivery with an ...
  https://www.bioportfolio.com/resources/trial/65146/Progesterone-17OHP-for-Prolongation-of-Pregnancy-in-Women-With-Preterm-Rupture-of.html
*  Identification of differentially expressed genes in fibroblasts derived from patients with Dupuytren's Contracture | BMC...
... and type XV collagen alpha 1 chain. Overall, our study has identified a variety of candidate genes that may be involved in the ... 3-alpha)-hydroxysteroid dehydrogenase) (AKR1C1) 0.59 cDNA of Unknown Biological Function ... Hydroxysteroid (11-beta) dehydrogenase transcript variant 1 catalyzes the interconversion of biologically inactive ... Homo sapiens hydroxysteroid (11-beta) dehydrogenase 1 (HSD11B1), transcript variant 1, mRNA ...
  https://bmcmedgenomics.biomedcentral.com/articles/10.1186/1755-8794-1-10
*  Cervical ripening in humans: potential roles of estrogen, progesterone, and insulin-like growth factor-I. Changes in 17-beta,20...
20-alpha-hydroxysteroid dehydrogenase activity supporting an increase in the estrogen/progesterone ratio of human fetal ... A study examined the activity of 17-beta,10-alpha-hydroxysteroid dehydrogenase and its affect on the estrogen-progesterone ... The activity of 17-beta,10-alpha-hydroxysteroid dehydrogenase changed at the time of parturition. Around this time, its ... The enzyme 17-beta,10-alpha-hydroxysteroid dehydrogenase may play an important role in increasing the estrogen-progesterone ...
  http://www.readabstracts.com/Health/Cervical-ripening-in-humans-potential-roles-of-estrogen-progesterone-and-insulin-like-growth-factor-.html