Acyl-butyrolactones are not a widely recognized or established medical term. However, based on the individual words, it is possible that acyl-butyrolactones refer to a class of chemical compounds known as lactones, which contain a ring structure containing a carbonyl group (a double bond between a carbon atom and an oxygen atom) and a ester group. The term "acyl" suggests that one of the substituents on the lactone ring is an acyl group, which is a functional group consisting of a carbonyl group attached to a carbon atom or a hydrogen atom.

It's worth noting that while lactones are found in nature and can have various biological activities, they are not typically considered as a major class of compounds in medical or clinical contexts. If you have more specific information about acyl-butyrolactones or their potential relevance to medicine, I would be happy to try to provide further clarification.