- By using a biochemical, molecular, and cell biology-focused approach, we aim to identify potential biomarkers and therapeutic targets involved in these pathways that can then be utilised for the rationale improvement of cancer treatment. (ki.se)
- Increasing the efficacy of CD20 antibody therapy through the engineering of a new type II anti-CD20 antibody with enhanced direct and immune effector cell-mediated B-cell cytotoxicity. (rocheonline.se)
- The molecular biology of endometrial cancers and the implications for pathogenesis, classification, and targeted therapies. (cancercentrum.se)
- In particular, we are interested in those pathways responsible for maintaining the DNA molecule and the DNA precursor pool, both of which play critical roles in cancer biology and the response to cancer therapy. (ki.se)
- The experimental division of Renal Medicine comprises a number of 'state of the art' techniques and molecular biology methods to study vascular maintenance under uremic environment, calcification and early ageing. (karolinska.se)
- My research consists in identifying the molecular mechanisms that control neurogenesis and specification during development and neuronal homeostasis in adult, with a particular interest for pain-sensing neurons. (ki.se)
- We utilize epidemiological data from Sweden, EU and worldwide and make use of clinical and novel biomarkers data to predict and target vascular abnormalities towards amelioration of early vascular ageing under uremic environment. (karolinska.se)
- Gaining insight into these mechanisms could lead to targeted therapies for illnesses such as pain disorders. (ki.se)
- Alice Costantini from the research group Clinical Genetics will defend her thesis 'Genetic causes and molecular mechanisms underlying rare metabolic bone diseases' on June 14th, 2019. (ki.se)
- For this reason, understanding the pathogenesis of these diseases could eventually lead to the development of targeted therapies. (ki.se)
- 15.20-15.50 Targeted therapeutics of CLL - spring has arrived! (sfhem.se)
- Presentationen gjordes på AACR-NCI-EORTCs(1) konferens "Molecular Targets and Cancer Therapeutics" i San Francisco, USA. (activebiotech.com)
- Cancer stem cells (CSCs) pose a serious obstacle to cancer therapy as they can be responsible for poor prognosis and tumour relapse. (naturensparti.se)
- Potential for early antiretroviral therapy to reduce central nervous system HIV-1 persistence. (gu.se)