Acinic cell carcinoma found by recurrence of a mucous cyst in the sublingual gland.
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This case report describes an acinic cell carcinoma found by a recurrence of a ranula in the sublingual gland. A 42-year-old male was admitted to the hospital of the Tokyo Dental College with a swelling in his right oral floor but without pain. The lesion was treated by windowing the same day under the diagnosis of a ranula, but the swelling appeared again at the same area eight months after the first operation. A resection was performed, and the specimen was sent to the clinical laboratory for pathological diagnosis. Proliferating serous cells were seen in part of the wall of an exudative mucous cyst. PAS staining was partially positive, and immunohistochemical staining for S-100 protein, lactoferrin, and amylase were also positive in cytoplasmic granules. This report concludes that the pathological diagnosis is beneficial in clarifying the reasons for the recurrence of a benign lesion. (+info)
Salivary glands: report of a rare case of myoepithelial carcinoma involving tongue base treated by CO2 Laser.
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Epithelial-myoepithelial carcinoma is a rare malignant tumour of the salivary glands. Herewith, the clinical evolution, anatomo-pathological characteristics and treatment adopted are described in a case occurring in the minor salivary glands of the tongue base. To our knowledge, this location has not been previously described in the literature. In fact, due to the rarity of the epithelial-myoepithelial carcinoma, there is no uniformity of data in the literature and very different therapeutic strategies have been suggested. In this report, the possibility of applying conservative surgery using CO(2) Laser is proposed. Results obtained in the case described confirm that conservative surgery is feasible in this type of neoplastic lesion of the tongue. (+info)
Robotic-assisted transoral removal of a bilateral floor of mouth ranulas.
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Bilateral submandibular gland lymphoma in Sjogren's syndrome.
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Salivary gland lymphoma is associated with Sjogren's syndrome. A case of bilateral submandibular gland and sublingual gland lymphoma, arising in Sjogren's syndrome, is presented. A lymphoma involving more than one salivary gland may occur in Sjogren's syndrome, and there is an increased risk of developing an extrasalivary lymphoma. (+info)
Epstein-Barr virus (EBV) infection in salivary gland tumors: lytic EBV infection in nonmalignant epithelial cells surrounded by EBV-positive T-lymphoma cells.
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To elucidate the association of Epstein-Barr virus (EBV) and salivary gland tumors, 114 cases of tumors of major salivary glands were investigated. EBV DNA was detected in all 6 cases of undifferentiated carcinoma and all 3 cases of T-cell lymphoma, but not in other tumor tissues. In situ hybridization studies for EBV DNA and EBV-encoded small RNA 1 (EBER1) showed specific localization of the EBV sequences to the undifferentiated carcinoma cells and T-lymphoma cells. Moreover, intense DNA signals were detected on nonneoplastic epithelial cells of T-lymphoma tissues. These epithelial cells were negative for EBER1 and expressed BZLF1, BALF2, and gp350/220 proteins associated with virus production. In contrast, nonmalignant epithelial cells surrounded by undifferentiated carcinoma cells showed no evidence of EBV infection or virus replication. These results indicate that there is an unusual association of salivary gland T-cell lymphomas with lytic EBV replication of nonmalignant epithelial cells. (+info)