Potential exposure of hands inside protective gloves-a summary of data from non-agricultural pesticide surveys.
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The results of individual surveys are compared and general observations are made about the protective nature of protective gloves. A total of 190 measurements of contamination by involatile components of pesticide products were made inside the gloves. Protective gloves were nearly always found to be contaminated inside, except for public hygiene insecticide uses. Disposable gloves were sometimes used when applying public hygiene insecticides, while gloves worn for other applications were normally re-used. The data suggest that when expressing inner glove exposure as 'amount of product per unit time', the data distributions of the non-zero results appeared similar for all activities except for the application of antifoulings. A median value for all non-zero data was indicated at 1.36mg product per minute; a 75th percentile at 4.21mg min(-1) and a 95th percentile at 71.9mg min(-1), assuming product densities of 1.0g ml(-1). In default of better information, these indicators can be used in health-based risk assessment. A further 47 data related to exposure inside new gloves, and 21 data to deposition on outer gloves. These indicate that in general, gloves provide a reasonable degree of protection to non-agricultural pesticides. Due regard should be paid to 'human factors' when considering contamination inside gloves. When people take off dirty gloves, it is difficult to avoid touching the glove exterior. With gloves off, the subject can touch contaminated surfaces. Donning dirty gloves furnishes an inevitable contact with contamination on the outside of the gloves, and can introduce that contamination inside. A common mode of contamination could contribute to the similar distributions for hand contamination inside gloves, from very different uses. (+info)
A novel method of assessing the effectiveness of protective gloves--results from a pilot study.
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We have devised a novel method for evaluating the effectiveness of protective gloves and have undertaken a small study to assess this approach. Three types of glove were tested in a standardised simulation test with a permethrin-based pesticide. Prewashed cotton gloves were used to collect the samples. One was worn over the protective glove on one hand to measure the potential deposition of pesticide on the hands had the gloves not been worn. A second was placed under the protective glove on the opposite hand to measure the actual deposition of permethrin on the hands when the gloves were worn. This regime was reversed half way through each test in an attempt to prevent bias. Measurable inner glove contamination occurred on 25 out of 30 occasions. Geometric mean protection factors were calculated from the ratio of outer and inner sampling glove contamination, with average protection factors of 470, 200 and 96 being obtained for the two nitrile and PVC gloves, respectively. The PVC gloves were the least effective in preventing inner glove contamination, probably because the glove was thick and fairly inflexible, causing more pesticide to enter the glove around the cuff. Although the tasks were standardised, variability occurred due to worker behaviour and equipment failure. The spray pump failed on five occasions, resulting in higher levels of inner glove contamination and a geometric mean protection factor of 32. On the occasions when the pump worked correctly, the level of protection provided by the gloves rose dramatically with mean protection factors of 220 and 450 being obtained for workers categorised as "messy" and "tidy", respectively. (+info)
Effectiveness of gloves in the prevention of hand carriage of vancomycin-resistant enterococcus species by health care workers after patient care.
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Gloving reduces acquisition of vancomycin-resistant Enterococcus species (VRE) on the hands, and it should be considered for routine inpatient care, even for contact with the intact skin of patients who may be colonized with VRE. However, gloving does not completely prevent contamination of the hands, and hand washing is necessary after glove removal. (+info)
Dermal in vitro penetration of methiocarb, paclobutrazol, and pirimicarb: effect of nonylphenolethoxylate and protective gloves.
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Dermal exposure has become the major route of human occupational exposure to pesticides. Detergents are used as part of formulated pesticide products and are known to change the barrier properties of human skin in vitro. However, studies on the influence of detergents as well as protective glove materials on dermal penetration of pesticides are scarce. In an experiment using in vitro static diffusion cells mounted with human skin, we evaluated the effect of nonylphenol-ethoxylate on dermal penetration of three extensively used pesticides--methiocarb, paclobutrazol, and pirimicarb--and the protection against dermal penetration offered by protective gloves made of latex or nitrile. There was a general tendency, though not statistically significant for all pesticides, for nonylphenolethoxylate to decrease the percutaneous penetration of the three pesticides. The nitrile generally offered better protection against percutaneous penetration of pesticides than did latex, but the degree of protection decreased over time and depended on the pesticides used. (+info)
Controlling antimicrobial resistance in hospitals: infection control and use of antibiotics.
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Antimicrobial-drug resistance in hospitals is driven by failures of hospital hygiene, selective pressures created by overuse of antibiotics, and mobile genetic elements that can encode bacterial resistance mechanisms. Attention to hand hygiene is constrained by the time it takes to wash hands and by the adverse effects of repeated handwashing on the skin. Alcohol-based hand rubs can overcome the time problem and actually improve skin condition. Universal glove use could close gaps left by incomplete adherence to hand hygiene. Various interventions have been described to improve antibiotic use. The most effective have been programs restricting use of antibiotics and computer-based order forms for health providers. (+info)
Distributions and determinants of pre-emergent herbicide exposures among custom applicators.
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Custom applicators intensively apply herbicides to corn and soybean fields each spring. The primary objective of this study was to characterize the exposure distributions of the herbicides alachlor, atrazine, 2,4-D 2-ethylhexyl ester (2,4-D EH), and metolachlor among a group of applicators during the spring pre-emergent spray season. A secondary objective was to evaluate determinants of exposure and to estimate within- and between-worker variance components. Fifteen applicators were sampled using a systematic design that included spray and non-spray days and multiple measurements (five to seven) on each applicator. Air, patch, and handwash samples were collected on 89 applicator-days. Applicator-days were classified into three categories: target herbicide sprayed, non-target herbicide sprayed, and no herbicide sprayed. Mixed-model regression analysis was used. For all exposure metrics, adjusted mean herbicide exposures were significantly higher on days when target herbicides were sprayed as compared to non-spray days. For 2,4-D EH only, adjusted mean exposures on non-target herbicide spray days were significantly higher than on non-spray days. Wearing gloves significantly reduced adjusted mean hand exposure for all herbicides (4-20 fold) and adjusted mean thigh exposure for three herbicides (8-53 fold) on days the herbicides were sprayed; however, wearing gloves significantly increased adjusted mean atrazine hand and thigh exposures (9 and 7 fold, respectively) on days that non-atrazine herbicides were sprayed. Few of the other covariates were consistent determinants of exposure. For all exposure metrics, the within-worker variability (GSD(W) 2.1-5.6) was greater than the between-worker variability (GSD(B) 1.2-2.7). (+info)
Sensitisation to natural rubber latex: an epidemiological study of workers exposed during tapping and glove manufacture in Thailand.
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OBJECTIVES: To estimate the prevalence of sensitisation to natural rubber latex in latex tappers and latex glove factory workers, and to relate this to airborne exposure to latex. METHODS: Five hundred workers employed in three latex glove factories, 314 tappers, and 144 college students (control group) were studied. The workers in the glove factories were classified into three exposure groups; high, moderate, and low. Personal exposures to natural rubber latex aeroallergens were measured by immunoassay. Symptom questionnaires and skin prick tests with latex allergens (Stallergenes 1:200 w/v) and other common environmental allergens were performed. The criterion for positivity was a wheal reaction at least 3 mm in diameter greater than that to a diluent control. RESULTS: The geometric mean (GM) concentration of latex in air was 15.4 microg/m(3) for those employed in glove stripping, glove inspections, and packing of powdered gloves. The moderate exposure glove manufacturing group and the tappers had GM concentrations of 2.3 and 2.4 microg/m(3) respectively, compared with United Kingdom users of latex powdered gloves,who had GM concentrations of 0.5 microg/m(3). The prevalence of sensitisation to latex in the tappers and latex glove factory workers was 1.3% and 1.7% respectively. No positive cases were found among the college students. Workers who showed a positive skin prick test to latex were more likely to be atopic. Work related respiratory and dermatological symptoms were found in about 20% of each population studied, but were not related to the presence of positive latex prick tests. CONCLUSIONS: This study suggests that in the Thai latex industries, latex sensitisation is rare despite high concentrations of airborne exposure and is less prevalent than in the healthcare sector in Europe where skin exposure is greater. (+info)
Importance of temporal cues for tactile spatial- frequency discrimination.
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While scanning a textured surface with fingers, tactile information is encoded both spatially, by differential activation of adjacent receptors, and temporally, by changes in receptor activation during movements of the fingers across the surface. We used a tactile discrimination task to examine the dependence of human tactile perception on the availability of spatial and temporal cues. Subjects discriminated between spatial frequencies of metal gratings presented simultaneously to both hands. Tactile temporal cues were eliminated by preventing lateral hand movements; tactile spatial cues were eliminated by using gloves with an attached rubber pin. Analysis revealed separation of the subjects into two groups: "spatiotemporal" (ST) and "latent-temporal" (LT). Under normal conditions, the performance of ST subjects was significantly better than that of the LT subjects. Prevention of lateral movements impaired performance of both ST and LT subjects. However, when only temporal cues were available, the performance of ST subjects was significantly impaired, whereas that of the LT subjects either improved or did not change. Under the latter condition, LT subjects changed strategy to scanning with alternating hands, at velocities similar to the velocities normally used by ST subjects. These velocities generated temporal frequencies between 15 and 30 Hz. The LT subjects were unaware of their improved performance. Nine of ten LT subjects significantly improved their performance under normal conditions when trained to scan gratings using alternating hands and velocities similar to those used by ST subjects. We conclude that (1) temporal cues are essential for spatial-frequency discrimination, (2) human subjects vary in the tactile strategies they use for texture exploration, and (3) poor tactile performers can significantly improve by using strategies that emphasize temporal cues. (+info)