Sublingual Gland Neoplasms: Neoplasms of the sublingual glands.Sublingual Gland: A salivary gland on each side of the mouth below the TONGUE.Salivary Gland Neoplasms: Tumors or cancer of the SALIVARY GLANDS.Ranula: A form of retention cyst of the floor of the mouth, usually due to obstruction of the ducts of the submaxillary or sublingual glands, presenting a slowly enlarging painless deep burrowing mucocele of one side of the mouth. It is also called sublingual cyst and sublingual ptyalocele.Sebaceous Gland NeoplasmsAnal Gland Neoplasms: Tumors or cancer of the anal gland.Submandibular Gland: One of two salivary glands in the neck, located in the space bound by the two bellies of the digastric muscle and the angle of the mandible. It discharges through the submandibular duct. The secretory units are predominantly serous although a few mucous alveoli, some with serous demilunes, occur. (Stedman, 25th ed)Salivary Glands: Glands that secrete SALIVA in the MOUTH. There are three pairs of salivary glands (PAROTID GLAND; SUBLINGUAL GLAND; SUBMANDIBULAR GLAND).Perianal GlandsAdenoma, Pleomorphic: A benign, slow-growing tumor, most commonly of the salivary gland, occurring as a small, painless, firm nodule, usually of the parotid gland, but also found in any major or accessory salivary gland anywhere in the oral cavity. It is most often seen in women in the fifth decade. Histologically, the tumor presents a variety of cells: cuboidal, columnar, and squamous cells, showing all forms of epithelial growth. (Dorland, 27th ed)Parotid Neoplasms: Tumors or cancer of the PAROTID GLAND.Parotid Gland: The largest of the three pairs of SALIVARY GLANDS. They lie on the sides of the FACE immediately below and in front of the EAR.Carcinoma, Mucoepidermoid: A tumor of both low- and high-grade malignancy. The low-grade grow slowly, appear in any age group, and are readily cured by excision. The high-grade behave aggressively, widely infiltrate the salivary gland and produce lymph node and distant metastases. Mucoepidermoid carcinomas account for about 21% of the malignant tumors of the parotid gland and 10% of the sublingual gland. They are the most common malignant tumor of the parotid. (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p575; Holland et al., Cancer Medicine, 3d ed, p1240)Salivary Proteins and Peptides: Proteins and peptides found in SALIVA and the SALIVARY GLANDS. Some salivary proteins such as ALPHA-AMYLASES are enzymes, but their composition varies in different individuals.Serous Membrane: A thin lining of closed cavities of the body, consisting of a single layer of squamous epithelial cells (MESOTHELIUM) resting on a thin layer of CONNECTIVE TISSUE, and covered with secreted clear fluid from blood and lymph vessels. Major serous membranes in the body include PERICARDIUM; PERITONEUM; and PLEURA.Silver Proteins: Compounds of silver and proteins used as topical anti-infective agents.Palatal Neoplasms: Tumors or cancer of the PALATE, including those of the hard palate, soft palate and UVULA.Acinar Cells: Cells lining the saclike dilatations known as acini of various glands or the lungs.Mouth, Edentulous: Total lack of teeth through disease or extraction.Chloroprene: Toxic, possibly carcinogenic, monomer of neoprene, a synthetic rubber; causes damage to skin, lungs, CNS, kidneys, liver, blood cells and fetuses. Synonym: 2-chlorobutadiene.Carcinoma, Adenoid Cystic: Carcinoma characterized by bands or cylinders of hyalinized or mucinous stroma separating or surrounded by nests or cords of small epithelial cells. When the cylinders occur within masses of epithelial cells, they give the tissue a perforated, sievelike, or cribriform appearance. Such tumors occur in the mammary glands, the mucous glands of the upper and lower respiratory tract, and the salivary glands. They are malignant but slow-growing, and tend to spread locally via the nerves. (Dorland, 27th ed)Mouth FloorMucin-5B: A gel-forming mucin that is predominantly expressed by submucosal glands of airway tissues and the SUBLINGUAL GLAND. It is one of the principal components of high molecular weight salivary mucin.Myoepithelioma: A usually benign tumor made up predominantly of myoepithelial cells.Adenolymphoma: A benign tumor characterized histologically by tall columnar epithelium within a lymphoid tissue stroma. It is usually found in the salivary glands, especially the parotid.Submandibular Gland NeoplasmsSalivary Glands, Minor: Accessory salivary glands located in the lip, cheek, tongue, floor of mouth, palate and intramaxillary.

*  Pituitary Gland, Intermediate; Intermediate Lobe of Pituitary
... On-line free medical diagnosis assistant. Ranked list of ... Sublingual Gland Neoplasms. 1. + + +. 88. Carcinoma, Mucoepidermoid. 1. + + +. 89. Trophoblastic Tumor, Placental Site. 1. + + ...
*  adrenal glands
... On-line free medical diagnosis assistant. Ranked list of possible diseases from either several symptoms or a ... Sublingual Gland Neoplasms. 2. + + +. 43. Histoplasmosis. 2. + + +. 44. Hyperandrogenism. 2. + + +. 45. Adenoma, Pleomorphic. 2 ... Vascular Neoplasms. 1. + + +. We do not evaluate or guarantee the accuracy of any content in this site. Click here for the full ...
*  Sublingual space - Wikipedia
Pathology arising from the sublingual gland is rare, however, sublingual gland neoplasms are predominantly malignant and thus ... the sublingual salivary gland. Saliva from the sublingual gland drains through several small excretory ducts in the floor of ... sublingual and submental spaces are sometimes termed the perimandibular spaces, or the submaxillary space. "Sublingual space". ... the intrinsic muscles of the tongue and genioglossus separate the two halves of the sublingual space. The sublingual space ...
*  2018 ICD-10-CM Diagnosis Code C09: Malignant neoplasm of tonsil
C08.1 Malignant neoplasm of sublingual gland C08.9 Malignant neoplasm of major salivary gland, unspecified ... C06.80 Malignant neoplasm of overlapping sites of unspecified parts of mouth C06.89 Malignant neoplasm of overlapping sites of ... Malignant neoplasm of oropharynx. 2016 2017 2018 Non-Billable/Non-Specific Code Type 2 Excludes*malignant neoplasm of tonsil ( ... Malignant neoplasm of lingual tonsil. 2016 2017 2018 Billable/Specific Code Type 2 Excludes*malignant neoplasm of tonsil NOS ( ...
*  Neoplasm of head and neck (Concept Id: C0278996) - MedGen - NCBI
Representative examples include oral cavity squamous cell carcinoma, laryngeal squamous cell carcinoma, and salivary gland ... A primary or metastatic malignant neoplasm affecting the head and neck. ... Malignant Sublingual Gland Neoplasm. *Malignant Submandibular Gland Neoplasm. *Malignant Minor Salivary Gland Neoplasm* ... Head and Neck Neoplasms*Neoplasm of head and neck*Cancer of salivary gland*Malignant Major Salivary Gland Neoplasm*Major ...
*  ICD-10 Diagnosis Code D11.7 Benign neoplasm of other major salivary glands
sublingual. »gland or duct. C08.1. C79.89. D00.00. D11.7. D37.031. D49.0. »submandibular gland. C08.0. C79.89. D00.00. D11.7. ... Neoplasms (C00-D48) * Benign neoplasms, except benign neuroendocrine tumors (D10-D36) *Benign neoplasm of major salivary glands ... Benign neoplasm of other major salivary glands Long Description: Benign neoplasm of other major salivary glands This is the ... Salivary Gland Disorders Your salivary glands are in your mouth. You have three pairs of major salivary glands and hundreds of ...
*  papillary cystadenocarcinoma
A case is reported of a papillary cystadenocarcinoma of the sublingual gland which presented as a ranula. This is both rare in ... ovarian neoplasms*neoplasm staging*uterine neoplasms*endometrioid carcinoma*clear cell adenocarcinoma*endometrial neoplasms* ... local neoplasm recurrence*pancreatic neoplasms*mucinous cystadenocarcinoma*hysterectomy*lymphatic metastasis*neoplasm ... Papillary cystadenocarcinoma of the sublingual gland presenting as a ranula. M Danford. Wessex Centre for Plastic and ...
*  Two Cases of Solitary Fibrous Tumor Involving Urinary Bladder and a Review of the Literature
... sublingual gland, lung, mediastinum, pericardium, gastrointestinal tract, liver, kidney, peritoneum, adrenal gland, spinal cord ... P. Klemperer and C. B. Rabin, "Primary neoplasms of the pleura. A report of five cases," Archives of Pathology & Laboratory ... Solitary fibrous tumor (SFT) is a rare mesenchymal neoplasm that accounts for less than 2% of all soft-tissue tumors usually ... "Immunoblot analysis of CD34 expression in histologically diverse neoplasms," American Journal of Pathology, vol. 156, no. 1, pp ...
*  Salivary Gland Cancers - Renal and Urology News
Salivary gland neoplasms, particularly in the major glands, parotid, submandibular and sublingual, are frequently benign, ... Salivary gland tumors make up about 5% of all head and neck neoplasms, and causation is largely unknown. There has been an ... This is in contrast to minor salivary gland neoplasms which may arise virtually anywhere in the upper aero-digestive tract - ... Beware of other conditions that can mimic salivary gland cancer:. The usual clinical presentation of a salivary gland tumor is ...
*  2017/18 ICD-10-CM Codes D37*: Neoplasm of uncertain behavior of oral cavity and digestive organs
D37.031 Neoplasm of uncertain behavior of the sublingual salivary glands. * D37.032 Neoplasm of uncertain behavior of the ... D37.02 Neoplasm of uncertain behavior of tongue. * D37.03 Neoplasm of uncertain behavior of the major salivary glands* D37.030 ... D37 Neoplasm of uncertain behavior of oral cavity and digestive organs* D37.0 Neoplasm of uncertain behavior of lip, oral ... D37.05 Neoplasm of uncertain behavior of pharynx. * D37.09 Neoplasm of uncertain behavior of other specified sites of the oral ...
*  Conference 09 - 2010 Case: 03 20101020
... mainly parotid and submandibular and less commonly the sublingual gland). Histologically, these neoplasms are biphasic and are ... Salivary gland: Expanding and infiltrating the salivary gland (submandibular, parotid or sublingual gland, varying depending on ... Harderian glands, and clitoral glands and preputial glands. In humans, salivary gland myoepitheliomas are classified based on ... and Harderian glands. All participants interpreted the tumor as arising from the salivary gland, and thus considered a neoplasm ...
*  Salivary Gland Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] | HealthLink BC
Incidence and Mortality Salivary gland tumors are a morphologically and clinically diverse group of neoplasms, which may ... of all salivary gland neoplasms and approximately 35% of malignant salivary gland neoplasms.[1,12] This neoplasm occurs most ... Tumors of the salivary glands comprise those in the major glands (e.g., parotid, submandibular, and sublingual) and the minor ... Mesenchymal neoplasms Mesenchymal neoplasms account for 1.9% to 5% of all neoplasms that occur within the major salivary glands ...
*  11 Salivary Gland Diseases Flashcards by Jordan Sanger | Brainscape
Study 11 Salivary Gland Diseases flashcards from Jordan Sanger ... Are minor salivary gland neoplasms more common in upper lip or ... Of all minor salivary gland neoplasms, which location is most likely to have a benign neoplasm? ... If your patient is ,60 yrs old and has a benign salivary gland neoplasm, it is more likely to be what kind? ... if your patient is ,50 yrs old and has a benign salivary gland neoplasm, it is more likely to be what kind? ...
*  Pathology3 Flashcards by Languages 247365 | Brainscape
parotid gland tissue. • submandibular gland tissue. • sublingual gland tissue. • all of the above ... The most common site of intraoral minor salivary gland neoplasms is ?. • The most common site of intraoral major salivary gland ... is the most common salivary gland malignancy and makes up between 5 % and 9% of all salivary gland neoplasms.. • adenoid cystic ... Of the neoplasms affecting the major or minor glands, the ? is the most common.. • basal cell adenoma. • sebaceous adenoma. • ...
*  Salivary Gland Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] | Cigna
Incidence and Mortality Salivary gland tumors are a morphologically and clinically diverse group of neoplasms, which may ... Salivary Gland Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] ... of all salivary gland neoplasms and approximately 35% of malignant salivary gland neoplasms.[1 ,12 ] This neoplasm occurs most ... Tumors of the salivary glands comprise those in the major glands (e.g., parotid, submandibular, and sublingual) and the minor ...
*  Salivary Gland Cancer Treatment (PDQ )
... of all salivary gland neoplasms and approximately 35% of malignant salivary gland neoplasms. [1] [12] This neoplasm occurs most ... Tumors of the salivary glands comprise those in the major glands (e.g., parotid, submandibular, and sublingual) and the minor ... Of salivary gland neoplasms, more than 50% are benign, and approximately 70% to 80% of all salivary gland neoplasms originate ... 3] In AFIP data of salivary gland neoplasms, acinic cell carcinoma is the third most common salivary gland epithelial neoplasm ...
*  List of MeSH codes (C07) - Wikipedia
... salivary gland neoplasms MeSH C07.465.565.824.695 --- parotid neoplasms MeSH C07.465.565.824.882 --- sublingual gland neoplasms ... salivary gland neoplasms MeSH C07.465.815.718.589 --- parotid neoplasms MeSH C07.465.815.718.870 --- sublingual gland neoplasms ... submandibular gland neoplasms MeSH C07.465.565.925 --- tongue neoplasms MeSH C07.465.614.187 --- dental fistula MeSH C07.465. ... submandibular gland diseases MeSH C07.465.815.882.500 --- submandibular gland neoplasms MeSH C07.465.815.929 --- xerostomia ...
*  List of MeSH codes (C04) - Wikipedia
... salivary gland neoplasms MeSH C04.588.443.591.824.695 --- parotid neoplasms MeSH C04.588.443.591.824.882 --- sublingual gland ... sebaceous gland neoplasms MeSH C04.588.805.776 --- sweat gland neoplasms MeSH C04.588.839.500 --- muscle neoplasms MeSH C04.588 ... anal gland neoplasms MeSH C04.588.274.476.411.445 --- duodenal neoplasms MeSH C04.588.274.476.411.501 --- ileal neoplasms MeSH ... peritoneal neoplasms MeSH C04.588.322.078 --- adrenal gland neoplasms MeSH C04.588.322.078.265 --- adrenal cortex neoplasms ...
*  Salivary gland-like carcinoma of the lung - Wikipedia
... parotid glands, submandibular glands and sublingual glands) of the head and neck. Carcinoma is a term for malignant neoplasms ... Salivary gland-like carcinomas of the lung generally refers a class of rare cancers that arise from the uncontrolled cell ... whose structure and features closely resemble those of cancers that form in the major salivary glands ( ... cell carcinoma Adenocarcinoma Large cell carcinoma Adenosquamous carcinoma Sarcomatoid carcinoma Carcinoid tumor Salivary gland ...
*  A SLIP OF THE TONGUE; A CASE OF DUAL DIAGNOSIS | Journal of Neurology, Neurosurgery & Psychiatry
Background Adenoid cystic carcinoma is an uncommon malignant neoplasm of salivary glands. We present a case of sublingual gland ... Biopsy confirmed an adenoid cystic carcinoma of the right sublingual gland with perineural invasion. She was referred for ... subtle high signal and abnormal enhancement of right CN V at the foramen ovale and an enhancing lesion in right sublingual ...
*  Chapter 11 Flashcards by Ryan Davis | Brainscape
Parotid gland (70%). Minor glands (25%). Submandibular (~5%). Sublingual (. 70 Sublingual neoplasms have the highest likelihood ... Parotid gland. They most common is minor glands (remember that the palate is the most common minor gland neoplasm site) ... What is the most common site for minor salivary gland neoplasms? What percentage of minor salivary gland neoplasms occur here? ... Hyperplasia of normal gland. **remember that you must biopsy to rule out neoplasm because swelling on the hard palate is ...
*  Salivary gland tumour - Wikipedia
Salivary gland tumours or neoplasms are tumours that form in the tissues of salivary glands. The salivary glands are classified ... The major salivary glands consist of the parotid, submandibular, and sublingual glands. The minor salivary glands consist of ... Around 50% of the tumours found in the submandibular glands are benign. Sublingual gland tumours are very rare but if present, ... Treatment of Salivary Gland Neoplasms with fast neutron Radiotherapy. Arch Otolaryngol Head Neck Surg Vol 129 944-948 Sep 2003 ...
*  Salivary Gland | South Florida ENT
There are 3 major glands, these consist of the parotid, submandibular and sublingual glands. They are considered exocrine ... Traditional salivary gland surgery can be performed to remove the diseased gland for a number of reasons:. *. Benign neoplasm ... Salivary Gland. Salivary Gland. The salivary glands are divided into major and minor glands. ... should the submandibular gland need to be resected we also offer a more recently developed technique to allow the gland to be ...
*  Biopsy, diagnosis and treatment of cysts and tumors sub-cluster 41
This study assessed the clinical and histological features and therapeutic efficacy of 25 cases of sublingual gland tumours ... Congenital neoplasms are very rare in childhood and represent 2.5% of all paediatric tumours; the intrauterine or congenital ... The pineal gland is important in structure, function and in the pathology that can affect it. The significance of the pathology ... Prognostication for cystic neoplasms of the pancreas continues to evolve. Beyond simple size and cystic fluid CEA determination ...
*  Saliva testing - Wikipedia
Humans have three major salivary glands: parotid, submandibular, and sublingual. These glands, along with additional minor ... and neoplasms. The following conditions are among those that can be detected through saliva testing (list not comprehensive): ... Nitrate extracted from blood by the salivary gland, accumulates in saliva, which is then reduced to nitric oxide to have a ... Most of these substances enter the salivary gland acinus and duct system from the surrounding capillaries via the intervening ...

Serous demilunePolymorphous low-grade adenocarcinoma: Polymorphous low-grade adenocarcinoma, often abbreviated PLGA, is a rare, asymptomatic, slow-growing malignant salivary gland tumor. It is most commonly found in the palate.Xanthocanace ranulaSebaceous adenoma: Sebaceous adenoma is a cutaneous condition characterized by a slow-growing tumor usually presenting as a pink, flesh-coloured, or yellow papule or nodule.James et al.Submandibular gland: The paired submandibular glands are major salivary glands located beneath the floor of the mouth. They each weigh about 15 grams and contribute some 60–67% of unstimulated saliva secretion; on stimulation their contribution decreases in proportion as the parotid secretion rises to 50%.Dredge turning gland: Dredge Turning Gland is a Trailing Suction Hopper Dredger component.Weaire–Phelan structure: In geometry, the Weaire–Phelan structure is a complex 3-dimensional structure representing an idealised foam of equal-sized bubbles. In 1993, Trinity College Dublin physicist Denis Weaire and his student Robert Phelan found that in computer simulations of foam, this structure was a better solution of the "Kelvin problem" than the previous best-known solution, the Kelvin structure..Sialoblastoma: A sialoblastoma is a low-grade salivary gland neoplasm that recapitulates primitive salivary gland anlage. It has previously been referred to as congenital basal cell adenoma, embryoma, or basaloid adenocarcinoma.Julie Campbell TathamChloropreneAdenoid cystic carcinomaDark FieldsEpithelial-myoepithelial carcinoma: Epithelial-myoepithelial carcinoma, abbreviated EMCa, is a rare malignant tumour that typically arises in a salivary gland and consists of both an epithelial and myoepithelial component. They are predominantly found in the parotid glandSebaceous lymphadenoma: Sebaceous lymphadenoma is a benign tumour of the salivary gland.

(1/7) Acinic cell carcinoma found by recurrence of a mucous cyst in the sublingual gland.

This case report describes an acinic cell carcinoma found by a recurrence of a ranula in the sublingual gland. A 42-year-old male was admitted to the hospital of the Tokyo Dental College with a swelling in his right oral floor but without pain. The lesion was treated by windowing the same day under the diagnosis of a ranula, but the swelling appeared again at the same area eight months after the first operation. A resection was performed, and the specimen was sent to the clinical laboratory for pathological diagnosis. Proliferating serous cells were seen in part of the wall of an exudative mucous cyst. PAS staining was partially positive, and immunohistochemical staining for S-100 protein, lactoferrin, and amylase were also positive in cytoplasmic granules. This report concludes that the pathological diagnosis is beneficial in clarifying the reasons for the recurrence of a benign lesion.  (+info)

(2/7) Salivary glands: report of a rare case of myoepithelial carcinoma involving tongue base treated by CO2 Laser.

Epithelial-myoepithelial carcinoma is a rare malignant tumour of the salivary glands. Herewith, the clinical evolution, anatomo-pathological characteristics and treatment adopted are described in a case occurring in the minor salivary glands of the tongue base. To our knowledge, this location has not been previously described in the literature. In fact, due to the rarity of the epithelial-myoepithelial carcinoma, there is no uniformity of data in the literature and very different therapeutic strategies have been suggested. In this report, the possibility of applying conservative surgery using CO(2) Laser is proposed. Results obtained in the case described confirm that conservative surgery is feasible in this type of neoplastic lesion of the tongue.  (+info)

(3/7) Robotic-assisted transoral removal of a bilateral floor of mouth ranulas.


(4/7) Carcinoma ex pleomorphic adenoma of the sublingual gland: a case report.


(5/7) Mucoepidermoid carcinoma of sublingual gland: a malignant neoplasm in an uncommon region.


(6/7) Bilateral submandibular gland lymphoma in Sjogren's syndrome.

Salivary gland lymphoma is associated with Sjogren's syndrome. A case of bilateral submandibular gland and sublingual gland lymphoma, arising in Sjogren's syndrome, is presented. A lymphoma involving more than one salivary gland may occur in Sjogren's syndrome, and there is an increased risk of developing an extrasalivary lymphoma.  (+info)

(7/7) Epstein-Barr virus (EBV) infection in salivary gland tumors: lytic EBV infection in nonmalignant epithelial cells surrounded by EBV-positive T-lymphoma cells.

To elucidate the association of Epstein-Barr virus (EBV) and salivary gland tumors, 114 cases of tumors of major salivary glands were investigated. EBV DNA was detected in all 6 cases of undifferentiated carcinoma and all 3 cases of T-cell lymphoma, but not in other tumor tissues. In situ hybridization studies for EBV DNA and EBV-encoded small RNA 1 (EBER1) showed specific localization of the EBV sequences to the undifferentiated carcinoma cells and T-lymphoma cells. Moreover, intense DNA signals were detected on nonneoplastic epithelial cells of T-lymphoma tissues. These epithelial cells were negative for EBER1 and expressed BZLF1, BALF2, and gp350/220 proteins associated with virus production. In contrast, nonmalignant epithelial cells surrounded by undifferentiated carcinoma cells showed no evidence of EBV infection or virus replication. These results indicate that there is an unusual association of salivary gland T-cell lymphomas with lytic EBV replication of nonmalignant epithelial cells.  (+info)

  • duct
  • the deep part of the submandibular gland and the submandibular duct (Wharton's duct) some extrinsic tongue muscle fibers. (
  • Incision of the plica itself can result in a ranula, or an incision placed medial to the plica can damage Wharton's duct, the sublingual artery and veins and the lingual nerve. (
  • Salivary calculus can be a serious problem, leading to stasis in the duct of the gland which can cause pain and a serious neck infection. (
  • Traditionally patients with these problems were offered surgery consisting of either blind removal of stone and dilation of duct or removal of the gland itself. (
  • Most of these substances enter the salivary gland acinus and duct system from the surrounding capillaries via the intervening tissue fluid, although some substances are produced within the glands themselves. (
  • The parotid gland is located in front of the ear, and it secretes its mostly serous saliva via the parotid duct (Stenson duct) into the mouth, usually opening roughly opposite the maxillary second molar. (
  • The submandibular gland is located medial to the angle of the mandible, and it drains its mixture of serous and mucous saliva via the submandibular duct (Wharton duct) into the mouth, usually opening in a punctum located in the floor of mouth. (
  • This irritation also causes inflammation of the duct openings of the minor salivary glands of the palate, and they become dilated. (
  • Frey's syndrome Salivary gland neoplasm A salivary diverticulum (plural diverticuli) is a small pouch or out-pocketing of the duct system of a major salivary gland. (
  • Several factors have been postulated: Formation of a hard salivary calculus or sialolith by accumulation of calcium salts in the duct of the salivary gland (a process known as Sialolithiasis). (
  • Cystic
  • Macroscopically, the neoplasms are dark red to yellow, solid to cystic masses filled with mucus, blood and necrotic cellular debris. (
  • Sialadenitis
  • Sialadenitis is inflammation of a salivary gland, usually caused by infections, although there are other less common causes of inflammation such as irradiation, allergic reactions or trauma. (
  • Chronic sclerosing sialadenitis is a chronic (long-lasting) inflammatory condition affecting the salivary gland. (
  • biopsy
  • Tissue biopsy is not usually indicated, but if carried out, the histopathologic appearance is usually normal salivary gland tissue. (
  • Sometimes attempted biopsy of Stafne defects reveals an empty cavity (possibly because the gland was displaced at the time of biopsy), or other contents such as blood vessels, fat, lymphoid or connective tissues. (
  • Cancers
  • Although exposure to ionizing radiation has been implicated as a cause of salivary gland cancer, the etiology of most salivary gland cancers cannot be determined. (
  • 2 , 3 , 5 , 6 ] Occupations associated with an increased risk for salivary gland cancers include rubber products manufacturing, asbestos mining, plumbing, and some types of woodworking. (
  • Salivary gland-like carcinomas of the lung generally refers a class of rare cancers that arise from the uncontrolled cell division (mitosis) of mutated cancer stem cells in lung tissue. (
  • In the United States, salivary gland cancers are uncommon with an incidence rate of 1.7 in 100000 between 2009 and 2013. (
  • connective
  • Eventual periductal and interlobular (inside the gland) sclerosis (replacement of regular tissue with hard connective tissue). (
  • Immune, especially autoimmune, cause - which has gained steam, given the observation that the tissue of the glands is overrun with lymphoid immune cells and fibrous connective tissue, as well as corroboration from markedly similar lesions (with histologic and immunohistochemical findings) seen elsewhere in the body. (
  • ducts
  • Saliva from the sublingual gland drains through several small excretory ducts in the floor of the mouth. (
  • Radio-active iodine administration can also lead to dysfunction of the excretory ducts of the saliva glands. (
  • New methods for managing salivary calculus, post-radiation salivary stasis and stenosis of salivary ducts have emerged using semi-rigid endoscopes which can be used to diagnose as well as to remove stones and dilate ducts to restore that gland back to its healthy state. (
  • Abnormalities of the salivary gland ducts leading to excessive accumulation or retention of ductal secretions, which can excite chronic inflammations. (
  • tissue
  • The Stafne defect is thought to be a normal anatomical variant, as the depression is created by ectopic salivary gland tissue associated with the submandibular gland and does not represent a pathologic lesion as such. (
  • Rarely, the defect can be completely surrounded by bone, and this has been theorized to be the result of entrapment of embyonic salivary gland tissue within the bone. (
  • Computed tomography (CT) will show a shallow defect through the medial cortex of the mandible with a corticated rim and no soft tissue abnormalities, with the exception of a portion of the submandibular gland. (
  • Sialography may be sometimes used to help demonstrate the salivary gland tissue within the bone. (
  • It is thought to be created by an ectopic portion of salivary gland tissue which causes the bone of the mandible to remodel around the tissue, creating an apparent cyst like radiolucent area on radiographs. (