Lymphangioma: A benign tumor resulting from a congenital malformation of the lymphatic system. Lymphangioendothelioma is a type of lymphangioma in which endothelial cells are the dominant component.Lymphangioma, Cystic: A cystic growth originating from lymphatic tissue. It is usually found in the neck, axilla, or groin.Picibanil: A lyophilized preparation of a low-virulence strain (SU) of Streptococcus pyogenes (S. hemolyticus), inactivated by heating with penicillin G. It has been proposed as a noncytotoxic antineoplastic agent because of its immune system-stimulating activity.Mesenteric Cyst: A rare intra-abdominal tumor in the MESENTERY. Mesenteric cysts are usually benign and can be very large fluid-filled (2000 mL) lesions.Mediastinal Neoplasms: Tumors or cancer of the MEDIASTINUM.Intestinal Volvulus: A twisting in the intestine (INTESTINES) that can cause INTESTINAL OBSTRUCTION.Splenic Neoplasms: Tumors or cancer of the SPLEEN.Mesentery: A layer of the peritoneum which attaches the abdominal viscera to the ABDOMINAL WALL and conveys their blood vessels and nerves.Jejunal Neoplasms: Tumors or cancer in the JEJUNUM region of the small intestine (INTESTINE, SMALL).Abdomen, Acute: A clinical syndrome with acute abdominal pain that is severe, localized, and rapid in onset. Acute abdomen may be caused by a variety of disorders, injuries, or diseases.Klippel-Trenaunay-Weber Syndrome: A congenital disorder that is characterized by a triad of capillary malformations (HEMANGIOMA), venous malformations (ARTERIOVENOUS FISTULA), and soft tissue or bony hypertrophy of the limb. This syndrome is caused by mutations in the VG5Q gene which encodes a strong angiogenesis stimulator.Kasabach-Merritt Syndrome: Rapidly growing vascular lesion along the midline axis of the neck, upper trunk, and extremities that is characterized by CONSUMPTION COAGULOPATHY; THROMBOCYTOPENIA; and HEMOLYTIC ANEMIA. It is often associated with infantile Kaposiform HEMANGIOENDOTHELIOMA and other vascular tumors such as tufted ANGIOMA.Macroglossia: The presence of an excessively large tongue, which may be congenital or may develop as a result of a tumor or edema due to obstruction of lymphatic vessels, or it may occur in association with hyperpituitarism or acromegaly. It also may be associated with malocclusion because of pressure of the tongue on the teeth. (From Jablonski, Dictionary of Dentistry, 1992)Orbital Neoplasms: Neoplasms of the bony orbit and contents except the eyeball.Injections, Intralesional: Injections introduced directly into localized lesions.Hemangioendothelioma: A neoplasm derived from blood vessels, characterized by numerous prominent endothelial cells that occur singly, in aggregates, and as the lining of congeries of vascular tubes or channels. Hemangioendotheliomas are relatively rare and are of intermediate malignancy (between benign hemangiomas and conventional angiosarcomas). They affect men and women about equally and rarely develop in childhood. (From Stedman, 25th ed; Holland et al., Cancer Medicine, 3d ed, p1866)Incidental Findings: Unanticipated information discovered in the course of testing or medical care. Used in discussions of information that may have social or psychological consequences, such as when it is learned that a child's biological father is someone other than the putative father, or that a person tested for one disease or disorder has, or is at risk for, something else.Genital Neoplasms, Male: Tumor or cancer of the MALE GENITALIA.Retroperitoneal NeoplasmsVulvar Neoplasms: Tumors or cancer of the VULVA.Peritoneal Neoplasms: Tumors or cancer of the PERITONEUM.Tomography, X-Ray Computed: Tomography using x-ray transmission and a computer algorithm to reconstruct the image.

*  Giant mesenteric cystic lymphangioma presenting with abdominal pain and masquerading as a gynecologic malignancy
... arguing against a cystic mesothelial proliferation. The left ovary, although cystic, was uninvolved by the lymphangioma. ... Giant mesenteric cystic lymphangioma in an infant presenting with acute bowel obstruction. J Can Chir. 2009;5:E42-3. [PMC free ... Mesenteric cystic lymphangioma: a congenital and an acquired anomaly? Two cases and a review of the literature. J Ped Surg. ... Cystic lymphangioma of the mesentery causing intestinal obstruction. Singapore Med J. 2007;48:E265-7. [PubMed] ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC2994469/
*  Cystic hygroma - Wikipedia
A cystic hygroma, also known as cystic lymphangioma and macrocystic lymphatic malformation, is an often congenital ... Cystic hygroma can be associated with a nuchal lymphangioma or a fetal hydrops. Additionally, it can be associated with Turner ... In addition, cystic hygromas can be found in other body parts such as the arm, chest, legs, groin, and buttocks. Cystic ... If the cystic hygroma is large, a cesarean section may be performed. After birth, infants with a persistent cystic hygroma must ...
  https://en.wikipedia.org/wiki/Cystic_hygroma
*  FCH - RightDiagnosis.com
Cystic Hygroma) with alternative diagnoses, full-text book chapters, misdiagnosis, research treatments, prevention, and ... Cystic Hygroma: »Introduction: Cystic Hygroma »Symptoms of Cystic Hygroma FCH: Rare Disease. Office of Rare Diseases (ORD) of ... lymphangioma *ranula *thyroglossal duct cyst Terms associated with FCH:. Terms Similar to FCH:. *Familial nuchal bleb *Fetal ... Introduction: Cystic Hygroma »Symptoms of Cystic Hygroma FCH: Related Diseases. FCH: FCH is listed as a type of (or associated ...
  http://www.rightdiagnosis.com/medical/fch.htm
*  My Life With Lymphedema: Cystic lymphangioma: An unusual cause of lower limb lymphedema.]
Labels: Cystic lymphangioma; lower limb lymphedema; unilateral lymphedema; Ultrasonography; Magnetic resonance imaging ... Magnetic resonance imaging before then after gadolinium showed typical aspects of cystic lymphangioma and confirmed the ... The lesion was heterogeneous associating both tissular and cystic aspects. The lower limb lymphoscintigraphy showed an ... Cystic lymphangioma: An unusual cause of lower limb lymphedema.] Cystic lymphangioma: An unusual cause of lower limb lymphedema ...
  http://mylifewithlymphedema.blogspot.com/2008/07/cystic-lymphangioma-unusual-cause-of.html
*  Benign Lymphangioendothelioma Publications and Abstracts | PubFacts.com
Cardiac lymphangioma is a rare primary benign tumor of the heart. We report a 3-year-old with cystic lymphangioma encasing the ... Cystic lymphangioma of the lesser omentum in a pregnant woman: a case report and review of the literature.. *Authors: ... Lymphangioma of the pancreas is rare and presents as a large cystic mass in the retroperitoneum. The pancreatic origin can be ... Background: Omental cystic lymphangioma is an extremely rare abdominal mass caused by congenital malformation.. Case: An 8-year ...
  https://www.pubfacts.com/search/Benign+Lymphangioendothelioma
*  Cystic hygromas - Cystic Hygroma
Experiences, treatments and effects of this congenital defect also know as lymphangioma ... Filed Under: Cystic Hygroma Tagged With: Cystic hygromas, Genetic defects. Subscribe to Blog via Email. Enter your email ... OK-432 - A Promising Drug to Treat Cystic Hygroma. September 22, 2011. 1 Comment ...
  https://cystichygroma.net/tag/cystic-hygromas
*  Cystic Lymphangioma disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials
Cystic Lymphangioma, also known as cystic hygroma, is related to abdominal cystic lymphangioma and cavernous lymphangioma. An ... MalaCards integrated aliases for Cystic Lymphangioma:. Name: Cystic Lymphangioma 12 50 14 ... MalaCards organs/tissues related to Cystic Lymphangioma:. 39 Pancreas, Skin, Colon, Spleen, Breast, Adrenal Gland, Tongue ... Articles related to Cystic Lymphangioma:. (show top 50) (show all 412) id. Title. Authors. Year. ...
  http://www.malacards.org/card/cystic_lymphangioma
*  DMOZ - Health: Conditions and Diseases: Cardiovascular Disorders: Congenital Anomalies: Cystic Hygroma
Lymphangioma) : lymph - clear type fluid, angio - mas, oma - tumour is a very rare condition, it can range in its severity, it ... Cystic Hygroma: ( Lymphangioma) : lymph - "clear type fluid", angio - "mas", oma - "tumour" is a very rare condition, it can ...
  http://dmoztools.net/Health/Conditions_and_Diseases/Cardiovascular_Disorders/Congenital_Anomalies/Cystic_Hygroma/
*  Treatments Category - Cystic Hygroma
Experiences, treatments and effects of this congenital defect also know as lymphangioma ... Curing Cystic Hygroma Some Treatment Options. September 30, 2011. 1 Comment. Cystic Hygroma is a congenital defect mostly ... Filed Under: Treatments Tagged With: Is surgical care the right solution for the cystic hygroma, right solution for the cystic ... Filed Under: Cystic Hygroma, Treatments Tagged With: Alcohol, Bleomycin, OK-432. Is surgical care the right solution for the ...
  https://cystichygroma.net/treatments
*  Maddox's Journey: A BIG day, so much to report...
What is Cystic Hygroma?. A cystic hygroma (alternativley called Lymphangioma) is a mass that commonly occurs in the head and ... A cystic hygroma occurs as the baby grows in the womb. It forms from pieces of material that carry fluid and white blood cells ... After birth, a cystic hygroma usually looks like a soft bulge under the skin. The cyst may not be recognized at birth. It ... However, cystic hygromas can often invade other neck structures, making this impossible. ...
  http://maddoxsjourney.blogspot.com/2010/05/big-day-so-much-to-report.html?showComment=1274450197393
*  Chronic Low Back Pain due to Retroperitoneal Cystic Lymphangioma
Less than 1% of lymphangiomas is in the retroperitoneum. Lymphangioma is mostly asymptomatic. Chronic symptoms were reported in ... old girl with low back pain from 6 months ago with huge pelvic mass and diagnosis of retroperitoneal cystic lymphangioma. ... Abdominal cystic lymphangioma is a rare benign neoplasm. ... Abdominal cystic lymphangioma is a rare benign neoplasm. Less ... Chronic Low Back Pain due to Retroperitoneal Cystic Lymphangioma. Article 17, Volume 2, Issue 1, March 2014, Page 72-74 PDF ( ...
  http://abjs.mums.ac.ir/article_2380.html
*  Maddox's Journey: Bump in the road...
What is Cystic Hygroma?. A cystic hygroma (alternativley called Lymphangioma) is a mass that commonly occurs in the head and ... A cystic hygroma occurs as the baby grows in the womb. It forms from pieces of material that carry fluid and white blood cells ... After birth, a cystic hygroma usually looks like a soft bulge under the skin. The cyst may not be recognized at birth. It ... I will tell you that I was also born with a cystic hygroma on the left side of my face that hung from my cheek and mouth area. ...
  http://maddoxsjourney.blogspot.com/2010/06/bump-in-road.html?showComment=1279585417885
*  Curing Cystic Hygroma, Treatment Options
Some of the common agents that are used as treatment options for Curing Cystic Hygroma such as OK-432 and Bleomycin are ... Lymphangioma or hemangiomas when treated with IFN-alpha 2a result in complete shrinkage but still it has not been properly ... Cystic Hygroma is a congenital defect mostly affecting the head and neck portion in fetus or any other patient. This disease ... Curing Cystic Hygroma might seem really hard as there is not much information regarding them although the effort of some kind ...
  https://cystichygroma.net/2011/27-curing-cystic-hygroma-treatment-options
*  Treatment for Cystic hygroma by administering sclerosing agents
The treatment in medical terms for this cystic hygroma starts with monitoring the sclerosing agents ... How to give best treatment for Cystic hygroma? ... The use of this agent has been proposed for the lymphangiomas. ... Many of us would hardly get an idea as to why the cystic hygroma is being caused in our humans. The reasons could be several ... As cystic hygroma is known to be the benign diseases people generally look for the alternative treatments that are less toxic ...
  https://cystichygroma.net/2011/13-how-to-give-best-treatment-for-cystic-hygroma-by-administering-sclerosing-agents
*  Cystic Hygroma - Experiences, treatments and effects of this congenital defect also know as lymphangioma
Cystic Hygroma was first discussed in the year 1843 by Wernher, where it was said to be a congenital defect causing lesions in ... Filed Under: Cystic Hygroma Tagged With: Cystic hygromas, Genetic defects. Cystic Hygroma - A Congenital Defect affecting ... Cystic Hygroma. Experiences, treatments and effects of this congenital defect also know as lymphangioma ... Cystic Hygroma was first discussed in the year 1843 by Wernher, where it was said to be a congenital defect causing lesions in ...
  https://cystichygroma.net/page/2
*  031604 - Linfangioma cavernoso (Higroma qu stico) en una cr a porcina (Cavernous Lymphangioma (cystic hygroma) in a swine...
Cavernous Lymphangioma (cystic hygroma) in a swine breeding). , Veterinaria.org . La primera comunidad veterinaria de habla ... 031604 - Linfangioma cavernoso (Higroma qu stico) en una cr a porcina (Cavernous Lymphangioma (cystic hygroma) in a swine ... 031604 - Linfangioma cavernoso (Higroma qu stico) en una cr a porcina (Cavernous Lymphangioma (cystic hygroma) in a swine ... 031604 - Linfangioma cavernoso (Higroma qu stico) en una cr a porcina (Cavernous Lymphangioma (cystic hygroma) in a swine ...
  http://veterinaria.org/5578-revista-veterinaria-redvet-031604---linfangioma-cavernoso-higroma-quistico-en-una-cria-porcina-cavernous-ly.html
*  Broad ligament cystic lymphangioma: A case report | Journal of Medical Case Reports | Full Text
... was required to diagnose the lesion as a cystic lymphangioma. Lymphangiomas should be treated with total surgical excision. ... Broad ligament cystic lymphangioma is extremely rare. A 70-year-old multiparous woman presented with an abdominal mass of 20- ... Broad ligament lymphangiomas are extremely rare but must be considered as a differential diagnosis of cystic lesions in that ... A large cystic swelling was detected on computed tomography scan that was found to arise from the left adnexal region. This 19 ...
  https://jmedicalcasereports.biomedcentral.com/articles/10.1186/1752-1947-2-310
*  glossary:cystic lymphangioma [Lymphedema People]
glossary:cystic_lymphangioma. (1) A lymphangioma usually occurring in the neck and composed of large, multilocular, thin-walled ... glossary/cystic_lymphangioma.txt · Last modified: 2012/10/16 14:40 (external edit) ...
  http://m.www.lymphedemapeople.com/wiki/doku.php?id=glossary:cystic_lymphangioma
*  July 2012 - Volume 23 - Issue 4 : Journal of Craniofacial Surgery
Facial Cystic Lymphangioma in Adults. Biasotto, Matteo; Clozza, Emanuele; Tirelli, Giancarlo Biasotto, Matteo; Clozza, Emanuele ... New Treatment for Cystic Lymphangiomas of the Face and Neck: Cyst Wall Rupture and Cyst Aspiration Combined With Sclerotherapy ...
  https://journals.lww.com/jcraniofacialsurgery/Fulltext/2012/07000/href
*  EURORAD - Radiologic Teaching Files
Huge cystic lymphangioma of the pancreas: report of a case. Igarashi A, Maruo Y, Ito T, Ohsawa K, Serizawa A, Yabe M, Seki K, ... Pancreatic cystic lymphangioma. Author(s). Pedro Belo OlIiveira, Henrique Rodrigues, João Filipe Costa, Pedro Belo Soares, ... Cystic lymphangioma of the pancreas: CT and pathologic findings. Gray G, Fried K, Iraci J. Abdom Imaging. 1998 Jan-Feb; 23(1): ... Cystic lymphangioma of the pancreas: a case report with special reference to embryological development. Abe H, Kubota K, Noie T ...
  http://www.eurorad.org/eurorad/case.php?id=4506
*  EURORAD - Radiologic Teaching Files
The differential diagnosis between cystic lymphangiomas and other retroperitoneal cystic masses can be challenging and includes ... The aetiology of cystic lymphangiomas is unclear. The majority of them (90%) are discovered before the age of two years, which ... Chen C, Hsu S, Lin CH, Cheng MF, Yu JC (2005) Cystic lymphangioma of the jejunal mesentery in an adult: A case report. World J ... Sonographically, lymphangiomas are most often multiloculated cystic lesions. CT and MRI allow a more precise characterisation ...
  http://www.eurorad.org/eurorad/case.php?id=9292
*  Discussion | Vascular Birthmarks Foundation
Lymphatic Malformations aka Lymphangioma, Cystic Hygroma. https://www.facebook.com/Lymphatic-Malformations-aka-Lymphangioma- ...
  https://birthmark.org/node/379?do=newreply&p=11389
*  What Is Microbiology - Progressive Multifocal Leukoencephalopathy - Medicalrealm
What Is Genetic Disorder - Cystic Fibrosis * What Is Genetic Disorder - Familial Hypertrophic Cardiomyopathy ... What Is Dermatology - Lymphangioma * What Is Dermatology - Hailey - Hailey Disease * What Is Dermatology - Bullous Pemphigoid ...
  http://www.medicalrealm.net/what-is-microbiology---progressive-multifocal-leukoencephalopathy1.html
*  Share Your Birthmark Journey | Vascular Birthmarks Foundation
The Vascular Birthmarks Foundation provides support and resources for children and adults born with hemangiomas, port wine stains, and other vascular birthmarks.
  https://birthmark.org/node/106
*  List of diseases (C) - Wikipedia
... anemia Cystic fibrosis Cystic hamartoma of lung and kidney Cystic hygroma lethal cleft palate Cystic hygroma Cystic medial ... Caudal appendage deafness Caudal duplication Caudal regression syndrome Causalgia Cavernous hemangioma Cavernous lymphangioma ... facial neuromusculoskeletal syndrome Cystathionine beta synthetase deficiency Cystic adenomatoid malformation of lung Cystic ... contractures Congenital craniosynostosis maternal hyperthyroiditis Congenital cystic adenomatoid malformation Congenital cystic ...
  https://en.wikipedia.org/wiki/List_of_diseases_(C)

Lymphangioma circumscriptum: Superficial lymphatic malformation (also known as "Lymphangioma circumscriptum") is a congenital malformation of the superficial lymphatics, presenting as groups of deep-seated, vesicle-like papules resembling frog spawn, at birth or shortly thereafter.James, William; Berger, Timothy; Elston, Dirk (2005).Hygroma (canine disease): A hygroma, or a false bursa, is a discrete, fluid-filled sac that can form on the joints of dogs in response to repeated pressure, such as that from sitting on a hard surface. It is treated by draining the fluid and may be prevented by providing padded bedding.Mesenteric cyst: A mesenteric cyst () is a cyst in the mesenterium, and is one of the rarest abdominal tumors, with approximately 821 cases reported since 1507. The incidence is between 1 per 100,000 to 1 per 250,000 hospital admissions.Primary mediastinal B-cell lymphoma: Primary mediastinal B-cell lymphoma, abbreviated PMBL, is a type of lymphoma that rises in the mediastinum and predominantly affects young adults.Intestinal malrotationLittoral cell angioma: Littoral cell angioma, abbreviated LCA, and formally known as littoral cell angioma of the spleen, is a benign tumour of the spleen that arises from the cells that line the red pulp.Epiploic appendagitis: Epiploic appendagitis (EA) is an uncommon, benign, non-surgical, self-limiting inflammatory process of the epiploic appendices. Other, older terms for the process include appendicitis epiploica and appendagitis, but these terms are used less now in order to avoid confusion with acute appendicitis.Parkes Weber syndromeMacroglossiaOrbital lymphoma: Orbital lymphoma is a common type of non-Hodgkin lymphoma that occurs near or on the eye. Common symptoms include decreased vision and uveitis.Intravascular papillary endothelial hyperplasia: Intravascular papillary endothelial hyperplasia (also known as "Masson's hemangio-endotheliome vegetant intravasculaire," "Masson's lesion," "Masson's pseudoangiosarcoma," "Masson's tumor," and "Papillary endothelial hyperplasia") may mimic angiosarcoma, with lesions that are red or purplish 5-mm to 5-cm papules and deep nodules on the head, neck, or upper extremities.James, William; Berger, Timothy; Elston, Dirk (2005).Incidentaloma: In medicine, an incidentaloma is a tumor ([found by coincidence (incidentally) without clinical symptom]s or suspicion. Like other types of [[incidental findings, it is found during the course of examination and imaging for other reasons.Vulvar intraepithelial neoplasia: (ILDS D07.120) |Dense artery sign: In medicine, the dense artery sign or hyperdense artery sign is a radiologic sign seen on computer tomography (CT) scans suggestive of early ischemic stroke. In earlier studies of medical imaging in patients with strokes, it was the earliest sign of ischemic stroke in a significant minority of cases.

(1/83) Lymphangioma of the spleen in an elderly patient.

Splenic cystic lymphangioma is a very rare condition, and is classified among cystic proliferations of the spleen. It is considered to be the result of a developmental malformation of the lymphatic system and can involve the spleen alone or be a part of multiorgan disease. It is usually seen in children, often found incidentally. We describe a case of cystic lymphangioma of the spleen in an elderly woman putting emphasis on the rarity of the case in old age, and on the problems of differential diagnosis with the other cystic proliferations of the spleen, in particular hydatid disease, in the absence of histologic information.  (+info)

(2/83) Rapid determination of zygosity and common aneuploidies from amniotic fluid cells using quantitative fluorescent polymerase chain reaction following genetic amniocentesis in multiple pregnancies.

Following second-trimester twin amniocentesis, we used quantitative fluorescent polymerase chain reaction (QF-PCR) assays and polymorphic small tandem repeats (STR) for rapid determination of zygosity and common aneuploidies from amniotic fluid (AF) cells in four pregnancies with like-sex twins, fused placentae and inconclusive chorionicity. The first and the second cases were suspected to have inadvertent sampling of the same amniotic cavity twice. The first case showed a dizygotic (DZ) pattern and repeat amniocentesis was thus avoided. The second case was monozygotic (MZ) and was complicated by discordant fetal growth and twin-twin transfusion syndrome. The third case was associated with a co-twin malformation, occipital encephalocele. DNA studies revealed MZ twinning with a discordant structural defect. The fourth case was associated with co-twin abnormalities of cystic hygroma and hydrops fetalis. DNA studies showed DZ twinning with discordant structural and chromosomal defects. The QF-PCR assay with STR has the advantages of rapid determination of zygosity and common aneuploidies in AF cells. This simple test appears to be useful in the instances of possible inadvertent puncture of the same amniotic cavity twice during amniocentesis and of discordant fetal structural and/or chromosomal abnormalities following genetic amniocentesis in multiple pregnancies with uncertain chorionicity.  (+info)

(3/83) Management of orbital lymphangioma using intralesional injection of OK-432.

AIM: To treat orbital lymphangioma with an intralesional injection of OK-432 (group A Streptococcus pyogenes of human origin). METHOD: A 14 year old boy had a right orbital cystic lymphangioma. The visual acuity in the eye was 20/28. In an initial treatment, 0.02 mg of OK-432, was injected into the tumour after aspiration of the fluid contents, but no effect was seen. The second treatment was performed with 0.04 mg of OK-432. RESULT: 4 months later, the lesion had totally shrunk to fibrous tissue. The side effects were fever, a local inflammatory reaction lasting 3 days, and increased intraocular pressure, which was managed by draining the fluid contents. Visual acuity improved to 20/15, and the visual field defect and restriction of eye movement seen before treatment disappeared. No recurrence was noted 1 year after treatment. CONCLUSION: An intralesional injection of OK-432 shrunk the lymphangioma without functional disturbance and scar in the facial skin. OK-432 may be useful for orbital lymphangioma, but further studies are still warranted to determine efficacy, complications, and the optimal dose for safe treatment.  (+info)

(4/83) Cystic lymphangioma of the small-bowel mesentery: case report and a review of the literature.

Cystic lymphangioma of the small-bowel mesentery is a rare manifestation of an intraabdominal tumor in elderly patients. We present a case of a small-bowel mesentery lymphangioma, causing fever and chills and present clinical and pathologic features. Furthermore, etiology and differential diagnosis of this tumor are discussed.  (+info)

(5/83) Prognostic value of ultrasound findings of fetal cystic hygroma detected in early pregnancy by transvaginal sonography.

OBJECTIVE: To assess the prognostic value of first and early second trimester transvaginal ultrasound findings of fetal cystic hygroma such as volume, presence of septa and associated fetal anomalies or malformations. DESIGN: A prospective study of fetal cystic hygroma volume detected at 10-15 weeks of gestation by transvaginal scan. SUBJECTS: The study comprised a series of 33 cystic hygromas detected throughout the period March 1994 to March 1998 in 1918 pregnant women. METHODS: The volume of the hygroma and the presence of septa and other associated fetal anomalies or malformations were evaluated and correlated with fetal karyotype, persistence of the hygroma and pregnancy outcome. RESULTS: A volume equal to or greater than 75 mm3 revealed a sensitivity of 66.7% [eight of 12 cases; 95% confidence interval (CI), 34.9-90.1%] for the identification of abnormal fetal karyotype, 72.7% (eight of 11 cases; 95% CI, 39.0-90.4%) for the identification of persistence of the hygroma and 90% (nine of 10 cases; 95% CI, 55.5-99.7%) for identification of an unfavorable outcome of pregnancy. Furthermore, the prognostic value of ultrasound in determining pregnancy and fetal outcome were improved by combining data on the volume of the hygroma and the presence of associated anomalies or malformations. CONCLUSIONS: Measuring the volume of a cystic hygroma proves to be a useful ultrasound prognostic indicator in determining the risk of an associated karyotypic abnormality and adverse fetal and pregnancy outcome. However, due to limited sample size, caution is required in interpretation of the data and further studies are needed.  (+info)

(6/83) The progression of mediastinal lymphangioma in utero.

We describe a case of mediastinal lymphangioma that suddenly progressed in utero. The initial sonographic impression was one of pericardial effusion while the follow-up examination revealed a mediastinal cystic mass. At 35 weeks of gestation preterm labor occurred. An ultrasound examination performed at this time demonstrated the mediastinal cyst with internal hemorrhage and fetal hydrops. The cystic mass was resected 5 days after birth. The diagnosis of lymphangioma was made from histological examination. The infant was followed up for 18 months and remained well. We recommend frequent prenatal sonographic follow-up when a localized fluid collection is, shown in the mediastinum.  (+info)

(7/83) Five cases of the lymphangioma of the mediastinum in adult.

Mediastinal lymphangioma is rare disease. Above all cavernous type of mediastinal lymphangioma is very rare. We report 5 cases of mediastinal lymphangioma including cavernous type. CT was performed in all and revealed that they were smoothly marginated and cystic. All were surgically resected and specimens were classified pathologically into cystic type (3 cases), cavernous type (1 case) and mixed type of the two (1 case). MRI was performed in the cavernous type and suggested that the mass was lymphangioma because of pathognomonic lesion. Despite preoperative diagnosis of mediastinal lymphangioma is difficult, MRI is able to useful examination. In the follow-ups there has been no recurrence in our series.  (+info)

(8/83) Sonographic screening for fetal aneuploidy: first trimester.

OBJECTIVES: Screening for fetal aneuploidy is now possible during the first trimester using sonographic and biochemical markers. The aim of this review was to summarize the efficacy and use of nuchal translucency in screening for fetal aneuploidy, especially fetal Down syndrome, and other anomalies. METHODS: We reviewed available literature regarding first-trimester screening. This includes more than 16 studies of nuchal translucency as a marker for fetal aneuploidy published since 1995. RESULTS: Although early studies showed wide variation in detection of fetal Down syndrome when using nuchal translucency, more recent studies showed sensitivities of approximately 70% to 80%, for a 5% false-positive rate. Increased nuchal translucency has also been found to be a marker for other aneuploidies, including trisomy 18, trisomy 13, and Turner syndrome. Maternal serum biochemical screening can be used as a test for aneuploidy during the first trimester The 2 maternal serum markers that appear to be most useful in the late first trimester are the free beta subunit of human chorionic gonadotropin and pregnancy-associated plasma protein A. Together with maternal age, these markers yield a detection rate for trisomy 21 of approximately 60%, for a 5% false-positive rate. Because sonographic and biochemical markers appear to be largely independent, their combined risk results in improved detection rates compared with either method alone. As a result, the combination of nuchal translucency, biochemical markers, and maternal age has achieved a detection rate of approximately 85%, for a 5% false-positive level for detection of trisomy 21. A newly proposed "integrated" approach using a panel of first- and second-trimester markers suggests that further improvement in the screening performance is possible. A number of questions regarding first-trimester screening remain. We address some of these questions: is first-trimester screening more effective than second-trimester screening? How to account for intrauterine lethality? Is earlier diagnosis important, and will it be accepted by patients? Is first-trimester screening cost-effective? How should first-trimester screening be interpreted with second-trimester tests? CONCLUSIONS: Despite encouraging data and general enthusiasm for first-trimester screening for fetal Down syndrome and other aneuploidies, a number of questions remain about its implementation in the United States. Multicenter studies currently under way should help answer some of these questions.  (+info)