Chills: The sudden sensation of being cold. It may be accompanied by SHIVERING.Cold Temperature: An absence of warmth or heat or a temperature notably below an accustomed norm.Nuts: Botanically, a type of single-seeded fruit in which the pericarp enclosing the seed is a hard woody shell. In common usage the term is used loosely for any hard, oil-rich kernel. Of those commonly eaten, only hazel, filbert, and chestnut are strictly nuts. Walnuts, pecans, almonds, and coconuts are really drupes. Brazil nuts, pistachios, macadamias, and cashews are really seeds with a hard shell derived from the testa rather than the pericarp.Cold Climate: A climate characterized by COLD TEMPERATURE for a majority of the time during the year.Fever: An abnormal elevation of body temperature, usually as a result of a pathologic process.Betaine: A naturally occurring compound that has been of interest for its role in osmoregulation. As a drug, betaine hydrochloride has been used as a source of hydrochloric acid in the treatment of hypochlorhydria. Betaine has also been used in the treatment of liver disorders, for hyperkalemia, for homocystinuria, and for gastrointestinal disturbances. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1341)Locusta migratoria: A species of migratory Old World locusts, in the family ACRIDIDAE, that are important pests in Africa and Asia.Drug Evaluation: Any process by which toxicity, metabolism, absorption, elimination, preferred route of administration, safe dosage range, etc., for a drug or group of drugs is determined through clinical assessment in humans or veterinary animals.Trees: Woody, usually tall, perennial higher plants (Angiosperms, Gymnosperms, and some Pterophyta) having usually a main stem and numerous branches.Acclimatization: Adaptation to a new environment or to a change in the old.UtahLiver Abscess, Pyogenic: Single or multiple areas of PUS due to bacterial infection within the hepatic parenchyma. It can be caused by a variety of BACTERIA, local or disseminated from infections elsewhere such as in APPENDICITIS; CHOLECYSTITIS; PERITONITIS; and after LIVER TRANSPLANTATION.Food Handling: Any aspect of the operations in the preparation, processing, transport, storage, packaging, wrapping, exposure for sale, service, or delivery of food.Climate: The longterm manifestations of WEATHER. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)Climate Change: Any significant change in measures of climate (such as temperature, precipitation, or wind) lasting for an extended period (decades or longer). It may result from natural factors such as changes in the sun's intensity, natural processes within the climate system such as changes in ocean circulation, or human activities.Seasons: Divisions of the year according to some regularly recurrent phenomena usually astronomical or climatic. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)Infusions, Intravenous: The long-term (minutes to hours) administration of a fluid into the vein through venipuncture, either by letting the fluid flow by gravity or by pumping it.Amphotericin B: Macrolide antifungal antibiotic produced by Streptomyces nodosus obtained from soil of the Orinoco river region of Venezuela.Meat: The edible portions of any animal used for food including domestic mammals (the major ones being cattle, swine, and sheep) along with poultry, fish, shellfish, and game.

*  The Chills - Everything2.com
The Chills were an excellent pop band from New Zealand in the mid-to-late 1980's. They produced a string of great singles on ... The Chills were an excellent pop band from New Zealand in the mid-to-late 1980's. They produced a string of great singles on ...
  https://everything2.com/title/The+Chills
*  chilling - Wiktionary
chilling (comparative more chilling, superlative most chilling). *Becoming cold. *1936, Djuna Barnes, Nightwood, Faber & Faber ... chilling (plural chillings). *The act by which something is chilled. * 2004, Timothy D. J. Chappell, Reading Plato's Theaetetus ... It was a chilling story, but the children enjoyed it. *22 March 2012, Scott Tobias, AV Club The Hunger Games[1] Displaying a ... As they reached the street the 'Duchess' caught a swirling hem of lace about her chilling ankles.. ...
  https://en.wiktionary.org/wiki/chilling
*  CHILL FACTOR
Top music downloads 1. Whatever You Like, T.I. 2. I Kissed a Girl, Katy Perry 3. Disturbia, Rihanna 4. Got Money, Lil Wayne 5. Paper Planes, M.I.A. ...
  https://nypost.com/2008/10/06/chill-factor-50/
*  Chills - Undiagnosed Symptoms - MedHelp
I have a patient who is experiencing what he describes as chills up his back and the backs of his arms. He has a history of a ... I have a patient who is experiencing what he describes as chills up his back and the backs of his arms. He has a history of a ...
  https://www.medhelp.org/posts/Undiagnosed-Symptoms/Chills/show/1868646
*  Lawyer: Tear gas 'chills' protesters' rights
... tells MSNBC's Trymaine Lee why tear gas chills protesters First Amendment rights. ... tells MSNBC's Trymaine Lee why tear gas chills protesters First Amendment rights.Dec.12.2014 ...
  http://www.msnbc.com/msnbc/watch/lawyer-tear-gas-chills-protesters-rights-370886211909
*  Burberry profit warning chills luxury rivals | Reuters
British fashion house Burberry's profit warning on Tuesday gave the clearest sign yet that a slowdown in China and Europe's debt crisis is bringing a nearly three-year boom in demand for luxury goods to an end.
  https://www.reuters.com/article/us-burberry-warning/burberry-profit-warning-chills-luxury-rivals-idUSBRE88A0DT20120911
*  chill-outs - Wiktionary
Retrieved from "https://en.wiktionary.org/w/index.php?title=chill-outs&oldid=46835094" ...
  https://en.wiktionary.org/wiki/chill-outs
*  Snowden affair chills US-Latin American ties
WASHINGTON (AP) - America's 'backyard,' as Secretary of State John Kerry once referred to Latin America, is sprouting angry weeds as the scandal involving intelligence leaker Edward Snowden lays bare already thorny U.S. relations with Latin America.
  https://www.yahoo.com/news/snowden-affair-chills-us-latin-american-ties-153803859.html?ref=gs
*  Chill Your Cheeks | WIRED
We've got plenty of items on our ergonomic wish list to make the eight hours a day we spend chained to a chair more bearable, but honestly, an 'ass cooler' is not one of them. Frankly we had no idea that an overheated posterior was a workplace hazard. But if it is one you contend \[…\]
  https://www.wired.com/2006/08/chill-your-chee/
*  Chilled Metropolis
You are not logged in. If you sign up for an account, you can gain additional voting power over time, allowing your vote to have an even greater impact on submission scores! ...
  https://www.newgrounds.com/audio/listen/212435
*  The Chill
Well, folks, it's been a while, but the Chill is back. Sort of. My brother and I used to run a blog called MFBarkley. The site ...
  http://www.chicagonow.com/chill/category/sports/
*  Economic exodus quickly chills Catalonia's independence dream
The flight of banks and top corporations from Catalonia is turning into a stampede as the Spanish state tightens the garrote on the rebel government in Barcelona, exposing the desperate weakness of the independence movement.
  http://www.telegraph.co.uk/business/2017/10/06/economic-exodus-quickly-chills-catalan-exuberance/
*  Prelaunch Chill Was Discounted
... Thiokol Consultation Brought a Go-Ahead, NASA Tells Probers. By Boyce Rensberger. Washington ...
  http://www.washingtonpost.com/wp-dyn/content/article/2006/01/25/AR2006012501364_pf.html
*  The thrill of chills | bollywood | Hindustan Times
The thrill of chills With Indian viewers giving horror and supernatural fare on films and TV a thumbs-up, more producers are ...
  http://www.hindustantimes.com/bollywood/the-thrill-of-chills/story-uUEk1czTC24bqK3B3NVgiK.html
*  Chills - Webfont & Desktop font « MyFonts
... there is indeed a chill of fear in your heart and the blood in your veins is turning cold. Try your best not to shiver and... ... Is that the trees rustling, or the hinges on the gate? Pull up your covers as daylight grows dim... there is indeed a chill of ...
  http://www.myfonts.com/fonts/comicraft/chills/
*  Samantha Fish - Chills & Fever | Musician's Friend
Chills & Fever at Musician's Friend. Get a low price and free shipping on thousands of items. ... Alliance Samantha Fish - Chills & Fever. Release Date:05/19/2017;Notes:Vinyl LP pressing. 2017 release from the blues rocker. ... Alliance Samantha Fish - Chills & Fever. Skip to main content Skip to footer /*#janrain-paypal { display:none; }*/ # ... On Chills & Fever Samantha makes musical history enlisting members of the punk blues band The Detroit Cobras along with ...
  http://www.musiciansfriend.com/books-sheet-music-media/alliance-samantha-fish--chills-fever/k57107000000000
*  Brutal weather chills home-builder confidence - MarketWatch
This advertisement is provided by Bankrate, which compiles rate data from more than 4,800 financial institutions. Bankrate is paid by financial institutions whenever users click on display advertisements or on rate table listings enhanced with features like logos, navigation links, and toll free numbers. Dow Jones receives a share of these revenues when users click on a paid placement. ...
  https://www.marketwatch.com/story/brutal-weather-chills-home-builder-confidence-2014-02-18?link=MW_story_latest_news
*  Chilled - Everything2.com
Hardened on the surface or edge by chilling; as, chilled iron; a chilled wheel. 2. Painter,Paint. Having that cloudiness or ... Chilled (?), a. 1. Hardened on the surface or edge by chilling; as, chilled iron; a chilled wheel. ... Chill Out. ambient techno. Electro-Soma. Sins of the Fathers : Hope (one). Our Hero. A monkey is for life, not just for ...
  https://everything2.com/title/chilled
*  Bachmann chills out in a meat locker
2012 GOP presidential candidate Michele Bachmann tours an Iowa meat packing plant, and while doing so makes a statement about Iranian President Mahmoud Ahmadinejad. And in other water cooler news, the 'Daily Show' celebrates the end of don't ask, don't tell.
  http://www.msnbc.com/way-too-early/watch/bachmann-chills-out-in-a-meat-locker-43144259906
*  The big chill | New Scientist
Winter World: The ingenuity of animal survival by Bernd Heinrich, Ecco Press/HarperCollins, $24.95, ISBN 0060197447 Reviewed by Jonathan Beard
  https://www.newscientist.com/article/mg17723765-400-the-big-chill/
*  Cold War-era chills. Tourists welcome. - latimes
... themselves evoke a chill. The wall posters include one that is almost touching in its naivete, labeled "Actions of a Soldier ...
  http://articles.latimes.com/2007/jun/24/world/fg-bombshelter24
*  Pitt chills out UConn - NewsTimes
https://www.newstimes.com/news/article/Pitt-chills-out-UConn-100703.php ...
  https://www.newstimes.com/news/article/Pitt-chills-out-UConn-100703.php
*  Japan's 3D chiller - Variety
Japan's 3D chiller When Japanese helmer Takashi Shimuzu presents horror-thriller 'Tormented,' a 3D fantasy puzzle, out-of- ... Japan's 3D chiller. Shimizu takes format to new level. By John Hopewell ...
  http://variety.com/2011/digital/features/japan-s-3d-chiller-1118042278/
*  Chills And Spills - tribunedigital-orlandosentinel
Sunday's chiller was the coldest game in Jacksonville history, too, easily surpassing a 26 degree playoff game against the New ... What Jay probably meant was: In a 12-degree wind chill, against the worst team in the NFL, on a weekend usually designated for ... But here's the really bad part: By kickoff, the entire field was covered with snow, and gusting winds dropped the wind chill ... This was anything but a meaningless game to the Patriots, who played for nearly four hours in finger-numbing, bone-chilling, ...
  http://articles.orlandosentinel.com/2000-12-18/features/0012180358_1_wind-chill-9-degrees-fans
*  Chill EDM on Spotify
Chill EDM. By EDM Sauce. Only the best chill music hits on Spotify. The Chill EDM Playlist features songs from the leading ... Listen to Chill EDM now.. Listen to Chill EDM in full in the Spotify app ...
  https://open.spotify.com/user/edmsauce/playlist/4BmzJqVAWW4fodF5xWvWFZ

Wind chill warning: A wind chill warning is issued by Environment Canada or the National Weather Service of the United States when the wind chill is low enough that it becomes life-threatening.Cold shock response: Cold shock response is the physiological response of organisms to sudden cold, especially cold water.Split nut: A split nut is a nut that is split lengthwise into two pieces (opposed halves) so that its female thread may be opened and closed over the male thread of a bolt or leadscrew. This allows the nut, when open, to move along the screw without the screw turning (or, vice versa, to allow the screw to pass through the nut without turning).Mawson StationRabbit feverBetaine: A betaine (BEET-ah-een, ) in chemistry is any neutral chemical compound with a positively charged cationic functional group such as a quaternary ammonium or phosphonium cation (generally: onium ions) which bears no hydrogen atom and with a negatively charged functional group such as a carboxylate group which may not be adjacent to the cationic site. A betaine thus may be a specific type of zwitterion.Peat swamp forest: Peat swamp forests are tropical moist forests where waterlogged soil prevents dead leaves and wood from fully decomposing. Over time, this creates a thick layer of acidic peat.Acclimatization: Acclimatization (UK also acclimatisation; US also acclimation) is the process in which an individual organism adjusts to a gradual change in its environment (such as a change in temperature, humidity, photoperiod, or pH), allowing it to maintain performance across a range of environmental conditions. Acclimation occurs in a short period of time (days to weeks), and within the organism's lifetime (compare to adaptation).Clara W. BeebePyogenic liver abscessHadley Centre for Climate Prediction and Research: 140px|rightClimate change in the United Kingdom: Climate change in the United Kingdom has been a subject of protests and controversies, and various policies have been developed to mitigate its effects. It is estimated to demand at least 80-85% emission reductions in the EU during 2008-2050 with reductions as soon as technically possible.Four Seasons Baltimore and Residences: Four Seasons Hotel Baltimore is currently a 22 story highrise hotel complex building which opened on November 14, 2011. The building's construction began back in 2007 and went through several changes.White meat: White meat or light meat refers to the lighter-colored meat of poultry as contrasted with dark meat. In a more general sense, white meat may also refer to any lighter-colored meat, as contrasted with red meats like beef and some types of game.

(1/19) A randomized, double-blind comparative trial evaluating the safety of liposomal amphotericin B versus amphotericin B lipid complex in the empirical treatment of febrile neutropenia. L Amph/ABLC Collaborative Study Group.

In this double-blind study to compare safety of 2 lipid formulations of amphotericin B, neutropenic patients with unresolved fever after 3 days of antibacterial therapy were randomized (1:1:1) to receive amphotericin B lipid complex (ABLC) at a dose of 5 mg/kg/d (n=78), liposomal amphotericin B (L Amph) at a dose of 3 mg/kg/d (n=85), or L Amph at a dose of 5 mg/kg/d (n=81). L Amph (3 mg/kg/d and 5 mg/kg/d) had lower rates of fever (23.5% and 19.8% vs. 57.7% on day 1; P<.001), chills/rigors (18.8% and 23.5% vs. 79.5% on day 1; P<.001), nephrotoxicity (14.1% and 14.8% vs. 42.3%; P<.01), and toxicity-related discontinuations of therapy (12.9% and 12.3% vs. 32.1%; P=.004). After day 1, infusional reactions were less frequent with ABLC, but chills/rigors were still higher (21.0% and 24.3% vs. 50.7%; P<.001). Therapeutic success was similar in all 3 groups.  (+info)

(2/19) Rituximab dose-escalation trial in chronic lymphocytic leukemia.

PURPOSE: To conduct a dose-escalation trial of rituximab in patients with chronic lymphocytic leukemia (CLL) to define the maximum-tolerated dose (MTD), to evaluate first-dose reactions in patients with high circulating lymphocyte counts, and to assess the efficacy at higher versus lower doses. PATIENTS AND METHODS: Fifty patients with CLL (n = 40) or other mature B-cell lymphoid leukemias (n = 10) were treated with four weekly infusions of rituximab. The first dose was 375 mg/m(2) for all patients; dose- escalation began with dose 2 but was held constant for each patient. Escalated doses were from 500 to 2,250 mg/m(2). RESULTS: Toxicity with the first dose (375 mg/m(2)) was noted in 94% of patients but was grade 1 or 2 in most, predominantly fever and chills. Six patients (12%) experienced severe toxicity with the first dose, including fever, chills, dyspnea, and hypoxia in all six patients, hypotension in five, and hypertension in one. Toxicity on subsequent doses was minimal until a dose of 2,250 mg/m(2) was achieved. Eight (67%) of 12 patients had grade 2 toxicity, including fever, chills, nausea, and malaise, although no patient had grade 3 or 4 toxicity. Severe toxicity with the first dose was significantly more common in patients with other B-cell leukemias, occurring in five (50%) of 10 patients versus one (2%) of 40 patients with CLL (P <.001). The overall response rate was 40%; all responses in patients with CLL were partial remissions. Response rates were 36% in CLL and 60% in other B-cell lymphoid leukemias. Response was correlated with dose: 22% for patients treated at 500 to 825 mg/m(2), 43% for those treated at 1,000 to 1,500 mg/m(2), and 75% for those treated at the highest dose of 2,250 mg/m(2) (P =.007). The median time to disease progression was 8 months. Myelosuppression and infections were uncommon. CONCLUSION: Rituximab has significant activity in patients with CLL at the higher dose levels. Severe first-dose reactions were uncommon in patients with CLL, even with high circulating lymphocyte counts, but were frequent in patients with other mature B-cell leukemias in which CD20 surface expression is increased. Efficacy of rituximab was also significant in this group of patients.  (+info)

(3/19) Dacarbazine and interferon alpha with or without interleukin 2 in metastatic melanoma: a randomized phase III multicentre trial of the Dermatologic Cooperative Oncology Group (DeCOG).

In several phase II-trials encouraging tumour responses rates in advanced metastatic melanoma (stage IV; AJCC-classification) have been reported for the application of biochemotherapy containing interleukin 2. This study was designed to compare the efficacy of therapy with dacarbazine (DTIC) and interferon alpha (IFN-alpha) only to that of therapy with DTIC and IFN-alpha with the addition of interleukin 2 (IL-2) in terms of the overall survival time and rate of objective remissions and to provide an elaborated toxicity profile for both types of therapy. 290 patients were randomized to receive either DTIC (850 mg/m(2)every 28 days) plus IFN-alpha2a/b (3 MIU/m(2), twice on day 1, once daily from days 2 to 5; 5 MIU/m(2)3 times a week from week 2 to 4) with or without IL-2 (4.5 MIU/m(2)for 3 hours i.v. on day 3; 9.0 MIU/m(2) i.v. day 3/4; 4.5 MIU/m(2) s.c. days 4 to 7). The treatment plan required at least 2 treatment cycles (8 weeks of therapy) for every patient. Of 290 randomized patients 281 were eligible for an intention-to-treat analysis. There was no difference in terms of survival time from treatment onset between the two arms (median 11.0 months each). In 273 patients treated according to protocol tumour response was assessable. The response rates did not differ between both arms (P = 0.87) with 18.0% objective responses (9.7% PR; 8.3% CR) for DTIC plus IFN-alpha as compared to 16.1% (8.8% PR; 7.3% CR) for DTIC, IFN-alpha and IL-2. Treatment cessation due to adverse reactions was significantly more common in patients receiving IL-2 (13.9%) than in patients receiving DTIC/IFN-alpha only (5.6%). In conclusion, there was neither a difference in survival time nor in tumour response rates when IL-2, applied according to the combined intravenous and subcutaneous schedule used for this study, was added to DTIC and IFN-alpha. However, toxicity was increased in melanoma patients treated with IL-2. Further phase III trials with continuous infusion and higher dosages must be performed before any final conclusions can be drawn on the potential usefulness of IL-2 in biochemotherapy of advanced melanoma.  (+info)

(4/19) Therapeutic use of cytokines to modulate phagocyte function for the treatment of infectious diseases: current status of granulocyte colony-stimulating factor, granulocyte-macrophage colony-stimulating factor, macrophage colony-stimulating factor, and interferon-gamma.

The innate immune system represents the initial arm of host defense against pathogenic bacteria, fungi, and parasites. Neutrophils, monocytes, and tissue-based macrophages are major cellular components of this system. The potential ability to augment activity of the innate immune system has increased dramatically during the past 2 decades, with the discovery and development of cytokines. Four cytokines, namely granulocyte colony-stimulating factor (G-CSF), granulocyte-macrophage colony-stimulating factor (GM-CSF), macrophage colony-stimulating factor (M-CSF), and interferon (IFN)-gamma, have received increasing attention as potential adjunctive agents for the treatment of infectious diseases. In various animal models of infection, therapeutic administration of each of the 4 cytokines has been shown to enhance pathogen eradication and to decrease morbidity and/or mortality. However, variable therapeutic efficacy has been reported in clinical trials conducted to date. This review summarizes the current status of the use of G-CSF, GM-CSF, M-CSF, and IFN-gamma in the treatment of infectious diseases.  (+info)

(5/19) Phase 2 study of a combined immunochemotherapy using rituximab and fludarabine in patients with chronic lymphocytic leukemia.

This multicenter phase 2 trial investigated safety and efficacy of a new immunochemotherapeutic regimen combining rituximab (R) and fludarabine (F) in patients with fludarabine- and anthracycline-naive chronic lymphocytic leukemia (CLL). The rationale for using R + F includes single-agent efficacy of both drugs, in vitro synergism of R and F, and no apparent overlapping toxicity. Of 31 eligible patients with B-CLL enrolled, 20 were previously untreated and 11 relapsed. Treatment consisted of fludarabine administered at standard doses (25 mg/m(2)/d; days 1-5, 29-33, 57-61, and 85-89) and rituximab (375 mg/m(2)/d) given on days 57, 85, 113, and 151. Side effects such as fever, chills, and exanthema were generally mild (National Cancer Institute Common Toxicity Criteria [NCI-CTC] grade 1/2 in 48% and grade 3 and/or 4 in 3% of patients). Fever and chills were mainly associated with the first rituximab infusion. Hematologic toxicity included neutropenia (grade 1 and/or 2 in 26%, grade 3 and/or 4 in 42%) and thrombocytopenia (grade 1 and/or 2 in 19%, grade 3 and/or 4 in 9%). One patient died of cerebral bleeding during prolonged thrombocytopenia after the second cycle of fludarabine. There were a total of 32 infections in 16 patients, none of which was fatal. The overall response rate (complete remission [CR] and partial remission [PR]) was 87% (27 of 31 evaluable patients). In 20 previously untreated patients, 17 (85%) responded. Ten of 31 patients achieved CR (5 of 20 untreated; 5 of 11 pretreated; 9 of 21 Binet stage B, 1 of 10 Binet stage C). The median duration of response was 75 weeks. We conclude that the combination of rituximab and fludarabine is feasible and effective in patients with B-CLL.  (+info)

(6/19) An overview of the current clinical use of the anti-CD20 monoclonal antibody rituximab.

The chimeric anti-CD20 monoclonal antibody rituximab has become part of the standard therapy for patients with non-Hodgkin's lymphoma (NHL). To date, more than 300 000 patients have been treated with rituximab worldwide, including patients with indolent and aggressive NHL, Hodgkin's disease and other B-cell malignancies. Combination of rituximab with cytotoxic agents or cytokines has been explored in a number of different studies. Rituximab is now also approved for patients with diffuse large B-cell lymphoma when combined with standard CHOP chemotherapy (cyclophosphamide, doxorubicin, vincristine and prednisone). The monoclonal antibody is generally well tolerated. Most adverse events are infusion-associated, including chills, fever and rigor related to the release of cytokines.  (+info)

(7/19) A major outbreak of severe acute respiratory syndrome in Hong Kong.

BACKGROUND: There has been an outbreak of the severe acute respiratory syndrome (SARS) worldwide. We report the clinical, laboratory, and radiologic features of 138 cases of suspected SARS during a hospital outbreak in Hong Kong. METHODS: From March 11 to 25, 2003, all patients with suspected SARS after exposure to an index patient or ward were admitted to the isolation wards of the Prince of Wales Hospital. Their demographic, clinical, laboratory, and radiologic characteristics were analyzed. Clinical end points included the need for intensive care and death. Univariate and multivariate analyses were performed. RESULTS: There were 66 male patients and 72 female patients in this cohort, 69 of whom were health care workers. The most common symptoms included fever (in 100 percent of the patients); chills, rigors, or both (73.2 percent); and myalgia (60.9 percent). Cough and headache were also reported in more than 50 percent of the patients. Other common findings were lymphopenia (in 69.6 percent), thrombocytopenia (44.8 percent), and elevated lactate dehydrogenase and creatine kinase levels (71.0 percent and 32.1 percent, respectively). Peripheral air-space consolidation was commonly observed on thoracic computed tomographic scanning. A total of 32 patients (23.2 percent) were admitted to the intensive care unit; 5 patients died, all of whom had coexisting conditions. In a multivariate analysis, the independent predictors of an adverse outcome were advanced age (odds ratio per decade of life, 1.80; 95 percent confidence interval, 1.16 to 2.81; P=0.009), a high peak lactate dehydrogenase level (odds ratio per 100 U per liter, 2.09; 95 percent confidence interval, 1.28 to 3.42; P=0.003), and an absolute neutrophil count that exceeded the upper limit of the normal range on presentation (odds ratio, 1.60; 95 percent confidence interval, 1.03 to 2.50; P=0.04). CONCLUSIONS: SARS is a serious respiratory illness that led to significant morbidity and mortality in our cohort.  (+info)

(8/19) Risk of transmission of leptospirosis from infected cattle to dairy workers in southern Israel.

BACKGROUND: Leptospirosis is a zoonotic disease that occurs worldwide, found predominantly in agricultural workers, port workers and dairy workers. OBJECTIVE: To investigate the risk of disease transmission to dairy workers following an outbreak in 1999 of Leptospirosis hardjo in the dairy herds of two kibbutzim in southern Israel. METHODS: A seroepidemiologic survey of all the dairy workers from these two kibbutzim was conducted, including individual interview and examination. Data were collected on the presence of clinical symptoms of leptospirosis during the previous month. One month later the medical personnel on the two kibbutzim were contacted in order to determine if any worker had subsequently developed clinical signs or symptoms of leptospirosis. All dairy workers had blood drawn for serology. Those workers whose initial serology had been borderline for leptospirosis had a repeated serology test between 2 and 4 weeks later. Doxycycline was given prophylactically to all dairy workers on one kibbutz only. RESULTS: Either with or without chemoprophylaxis, no dairy workers exposed to herds infected with Leptospira hardjo showed evidence of seroconversion or disease. This indicated a low risk of transmission of this serovar from cows to dairy workers. CONCLUSION: Since human illness with leptospirae can cause illness associated with significant morbidity, we recommend that physicians make an informed decision regarding doxycycline prophylaxsis for dairy workers exposed to cattle herds infected with Leptospira hardjo.  (+info)



  • Listeners
  • After the release of the fifth edition, Matt Darey's Pure Euphoria in April 2000, Short and the other creators of Euphoria, credited as Tailormade Music, looked to create an edition that would not feature trance music or another form of dance music, but instead chill-out music for listeners to relax to. (wikipedia.org)
  • occurs
  • Shivering also occurs along with chills because the patient's body produces heat during muscle contraction in a physiological attempt to increase body temperature to the new set point. (wikipedia.org)
  • Postpartum chills is a physiological response that occurs within two hours of childbirth. (wikipedia.org)
  • scenes
  • Displaying a sturdy professionalism throughout that stops just short of artistry, director Gary Ross, who co-scripted with Collins and Billy Ray, does his strongest work in the early scenes, which set up the stakes with chilling efficiency. (wiktionary.org)
  • Chills is composed of a presenter, psychic medium, historian, main technology consultant and a backstage team of researchers and technicians, who work behind the scenes, mainly with Harrison and La Peruta. (wikipedia.org)
  • Behind the scenes, Diamond works as an intermediary between Chills and the various people involved. (wikipedia.org)
  • accompany
  • After discharge to home with the baby, chills that accompany uncontrolled bleeding, shortness of breath, cold clammy skin, dizziness, heart pain, and racing heart can be a sign of shock that needs immediate medical attention. (wikipedia.org)
  • chart
  • In the 1980s and 1990s, The Chills had some significant chart success in their homeland, and were a cult band in other parts of the world as one of the earliest proponents of the Dunedin Sound. (wikipedia.org)
  • Chills" has become the group's most successful single to date, becoming their first release to hit number one on the Canada Country chart and their first to chart on the Canadian Hot 100. (wikipedia.org)
  • In the United States, "Chills" also became their first single to chart on the Billboard Country Airplay chart, reaching a peak position of 58. (wikipedia.org)
  • supernatural
  • With the four titles' debuts set to be staggered over the course of four months, Marvel premiered Journey into Mystery vol. 2 (Oct. 1972), Chamber of Chills (Nov. 1972), Supernatural Thrillers (Dec. 1972), and, with a late start, Worlds Unknown (May 1973). (wikipedia.org)
  • Single
  • Chillers for industrial applications can be centralized, where a single chiller serves multiple cooling needs, or decentralized where each application or machine has its own chiller. (wikipedia.org)
  • Single malt whiskeys are usually chilled down to 0°C, while the temperature for blended whiskey tends to be lower since they have lower levels of fatty acid. (wikipedia.org)
  • band
  • Band personnel turnover was near-constant, with The Chills going through over 20 different line-up changes with Phillipps as the only constant member. (wikipedia.org)
  • Phillipps announced the dissolution of the Chills after the Soft Bomb tour, and joined David Kilgour in a loosely organized covers band known as The Pop Art Toasters, which released a self-titled EP in 1994. (wikipedia.org)
  • album
  • Chills" is a song recorded by Canadian rap rock group Down with Webster, taken from their second major-label studio album Party for Your Life (2014). (wikipedia.org)
  • Chilled Euphoria is a DJ mix album digitally mixed by British DJ Red Jerry as part of the Telstar TV's Euphoira series of DJ mixed dance music compilations. (wikipedia.org)
  • The album was intended to be played in "post club sessions", where people chill-out in their homes listening to the album after returning home from a dance nightclub at 8 am. (wikipedia.org)
  • Name
  • After Bull's death in July 1983 (from leukaemia), the Chills changed their name to A Wrinkle in Time, as Phillipps was initially unwilling to continue performing under a name associated with his late friend. (wikipedia.org)
  • Chamber of Chills is the name of two anthology horror comic books, one published by Harvey Publications in the early 1950s, the other by Marvel Comics in the 1970s. (wikipedia.org)
  • title
  • For example, the news headline "Flood insurance [price] spikes have chilling effect on some home sales," and the abstract title of a two‐part survey of 160 college students involved in dating relationships: "The chilling effect of aggressive potential on the expression of complaints in intimate relationships. (wikipedia.org)
  • commonly
  • Sometimes a chill of medium power and short duration may occur during a scare, especially in scares of fear, commonly interpreted like or confused by trembling. (wikipedia.org)
  • Chills are commonly caused by inflammatory diseases, such as the flu. (wikipedia.org)
  • However, the term is also now commonly used outside American legal jargon, such as the chilling effects of high prices or of corrupt police, or of "anticipated aggressive repercussions" (in say, personal relationships). (wikipedia.org)
  • effect
  • In a legal context, a chilling effect is the inhibition or discouragement of the legitimate exercise of natural and legal rights by the threat of legal sanction. (wikipedia.org)
  • The right that is most often described as being suppressed by a chilling effect is the US constitutional right to free speech. (wikipedia.org)
  • any coercion or threat of coercion (or other unpleasantries) can have a chilling effect on a group of people regarding a specific behavior, and often can be statistically measured or be plainly observed. (wikipedia.org)
  • In United States and Canadian law, the term chilling effects refers to the stifling effect that vague or excessively broad laws may have on legitimate speech activity. (wikipedia.org)
  • A chilling effect is an effect that reduces, suppresses, discourages, delays, or otherwise retards reporting concerns of any kind. (wikipedia.org)
  • An example of the "chilling effect" in Canadian case law can be found in Iorfida v. MacIntyre where the constitutionality of a criminal law prohibiting the publication of literature depicting illicit drug use was challenged. (wikipedia.org)
  • The court found that the law had a "chilling effect" on legitimate forms of expression and could stifle political debate on issues such as the legalization of marijuana. (wikipedia.org)
  • The court noted that it did not adopt the same "chilling effect" analysis used in American law but considered the chilling effect of the law as a part of its own analysis. (wikipedia.org)
  • The United States Supreme Court first refers to the "chilling effect" in the context of the United States Constitution in Wieman v. Updegraff in 1952. (wikipedia.org)
  • The "chilling effect" referred to at the time was a "deterrent effect" on freedom of expression-even when there is no law explicitly prohibiting it. (wikipedia.org)
  • However, in general, "chilling effect" is now often used in reference to laws or actions that do not explicitly prohibit legitimate speech, but that impose undue burdens. (wikipedia.org)
  • not in citation given] Censorship Culture of fear Opinion corridor Fear mongering Media transparency Prior restraint Strategic lawsuit against public participation chilling effect. (wikipedia.org)
  • Retrieved January 26, 2014 Communication Monographs, Volume 60, Issue 3, 1993 Denise H. Clovena & Michael E. Roloffb pages 199-219 "THE CHILLING EFFECT OF AGGRESSIVE POTENTIAL ON THE EXPRESSION OF COMPLAINTS IN INTIMATE RELATIONSHIPS" Abstract, by DH Cloven - 1993 -Published online: 02 Jun 2009 - (Cited by 99) "A two‐part survey of 160 college students involved in dating relationships. (wikipedia.org)
  • high
  • In computing, CHILL (an acronym for CCITT High Level Language) is a procedural programming language designed for use in telecommunication switches (the hardware used inside telephone exchanges). (wikipedia.org)
  • team
  • Chills is an upcoming television show and paranormal investigation team based in Brighton, UK. (wikipedia.org)
  • Technical consultant Alessandro La Peruta completed the team, and Chills was formed. (wikipedia.org)
  • Curtis Diamond, the co-founder of Chills, is the team host. (wikipedia.org)
  • He heads up a trained research team who intensively examine all aspects of the location selected by Chills. (wikipedia.org)
  • In addition to her job with the Australian Olympic team Chiller is the President of Modern Pentathlon Australia and has been appointed to the International Modern Pentathlon Union's 'Sport for All' Commission. (wikipedia.org)
  • Chiller continued her insistence upon discipline amongst current athletes, by banning Rio gold medallist Emma McKeon and fellow swimmer Josh Palmer from the Olympic closing ceremony after both breached team protocols. (wikipedia.org)
  • water
  • Chilled water is used to cool and dehumidify air in mid- to large-size commercial, industrial, and institutional facilities. (wikipedia.org)
  • In air conditioning systems, chilled water is typically distributed to heat exchangers, or coils, in air handlers or other types of terminal devices which cool the air in their respective space(s). (wikipedia.org)
  • The water is then recirculated to the chiller to be recooled. (wikipedia.org)
  • These cooling coils transfer sensible heat and latent heat from the air to the chilled water, thus cooling and usually dehumidifying the air stream. (wikipedia.org)
  • Chilled water temperatures can range from 35 to 45 °F (2 to 7 °C), depending upon application requirements. (wikipedia.org)
  • When the chillers for air conditioning systems are not operable or they are in need of repair or replacement, emergency chillers may be used to supply chilled water. (wikipedia.org)
  • Large chilled water hoses are used to connect between rental chillers and air conditioning systems. (wikipedia.org)
  • In industrial application, chilled water or other liquid from the chiller is pumped through process or laboratory equipment. (wikipedia.org)
  • Chill filtering prevents the whisky from becoming hazy when in the bottle, when served, when chilled, or when water or ice is added, as well as precluding sedimentation from occurring in the bottles. (wikipedia.org)
  • people
  • For this new edition, they drew inspiration from experiences where nightclubs would close at around 8 am, and clubbers would, after a somewhat frustrating journey home, finally return home "with a group of friends in tow" and "make the most out of the next few hours", an experience that they compared to fine art, where people would perform chill out activities. (wikipedia.org)
  • point
  • The increased set point causes the body temperature to rise (pyrexia), but also makes the patient feel cold or chills until the new set point is reached. (wikipedia.org)
  • group
  • Thomas Harvey, one of the lead lawyers for Ferguson protesters and co-founder of Arch City Defenders, a group that advocates for the poor and vulnerable, tells MSNBC's Trymaine Lee why tear gas chills protesters First Amendment rights. (msnbc.com)
  • Walking through the front door of home, with a group of friends in tow, it's Mission Accomplished and time to chill, providing you've come to an arrangement on who's making the tea, the toast and nobody has forgotten the Rizzlas. (wikipedia.org)
  • back
  • I have a patient who is experiencing what he describes as chills up his back and the backs of his arms. (medhelp.org)
  • This discussion is related to Weird back chills, please help . (medhelp.org)
  • form
  • Ten years of experience in developing himself into one of the foremost psychics in the country has led him to form Chills. (wikipedia.org)
  • Chilled Euphoria features chill-out music, in the form of genres such as ambient music and trip hop, cross-licensed from different artists. (wikipedia.org)
  • horror
  • The first Chamber of Chills was a 10-cent horror anthology published bimonthly by Harvey Publications that ran 26 issues (June 1951 - Dec. 1954). (wikipedia.org)
  • country
  • Country music blog The Shotgun Seat wrote that "Chills" is "a clear standout" on the EP, "with its rolling rhythm and fast-paced chorus. (wikipedia.org)
  • cold
  • there is indeed a chill of fear in your heart and the blood in your veins is turning cold. (myfonts.com)
  • process
  • Chill filtering works by reducing the temperature sufficiently that some fatty acids, proteins and esters (created during the distillation process) precipitate out so that they are caught on the filter. (wikipedia.org)
  • Factors affecting the chill filtering process include the temperature, number of filters used, and speed at which the whiskey is passed through the filters. (wikipedia.org)