Zanthoxylum: A plant genus of the family RUTACEAE. Some members of Zanthoxylum are reclassified from ELEUTHEROCOCCUS, Melicope, and EVODIA. The twigs are used as dental brushing sticks (TOOTHBRUSHING). Most plants that are called Fagara have been reclassified as Zanthoxylum, however some Fagara were reclassified to MELICOPE (also in the Rutacea family) or to GLEDITSIA (a genus in the FABACEAE family).Bufotenin: A hallucinogenic serotonin analog found in frog or toad skins, mushrooms, higher plants, and mammals, especially in the brains, plasma, and urine of schizophrenics. Bufotenin has been used as a tool in CNS studies and misused as a psychedelic.Medicine, African Traditional: A system of traditional medicine which is based on the beliefs and practices of the African peoples. It includes treatment by medicinal plants and other materia medica as well as by the ministrations of diviners, medicine men, witch doctors, and sorcerers.Plant Bark: The outer layer of the woody parts of plants.Oils, Volatile: Oils which evaporate readily. The volatile oils occur in aromatic plants, to which they give odor and other characteristics. Most volatile oils consist of a mixture of two or more TERPENES or of a mixture of an eleoptene (the more volatile constituent of a volatile oil) with a stearopten (the more solid constituent). The synonym essential oils refers to the essence of a plant, as its perfume or scent, and not to its indispensability.Plant Extracts: Concentrated pharmaceutical preparations of plants obtained by removing active constituents with a suitable solvent, which is evaporated away, and adjusting the residue to a prescribed standard.

*  Category:Zanthoxylum schinifolium - Wikimedia Commons
Media in category "Zanthoxylum schinifolium". The following 13 files are in this category, out of 13 total. ... Zanthoxylum schinifolium - VanDusen Botanical Garden - Vancouver, BC - DSC07116.jpg 5,472 × 3,648; 14.05 MB. ... Zanthoxylum schinifolium - VanDusen Botanical Garden - Vancouver, BC - DSC07118.jpg 5,472 × 3,648; 12.52 MB. ... Retrieved from "https://commons.wikimedia.org/w/index.php?title=Category:Zanthoxylum_schinifolium&oldid=107628891" ...
  https://commons.wikimedia.org/wiki/Category:Zanthoxylum_schinifolium
*  Mali trees can kill the Malaria carrying mosquito and its parasite Muslim Science
Now scholars from the University of Oslo extracted important compounds from the bark of the Olon (Zanthoxylum heitzii) tree ...
  http://muslim-science.com/mali-trees-can-kill-the-malaria-carrying-mosquito-and-its-parasite/
*  Medicinal Trees: Prickly Ash - Good Witches Homestead
Angelica Tree Prickly Ash Suterberry Toothache Tree The prickly ash or the Zanthoxylum americanum is a tall shrub that may also ... The prickly ash or the Zanthoxylum americanum is a tall shrub that may also be described as a small tree and usually grows up ... It may be mentioned here that the prickly ash tree found in China, which is known as the Zanthoxylum simulans, also possesses ...
  https://goodwitcheshomestead.com/2017/04/19/medicinal-trees-prickly-ash/
*  Plus it
In this study, we showed that nitidine chloride, a natural phytochemical alkaloid derived from Zanthoxylum nitidum (Roxb) DC, ...
  http://mct.aacrjournals.org/content/early/2012/01/27/1535-7163.MCT-11-0648
*  中国科学院西双版纳热带植物园机构知识库(XTBG OpenIR): Chemical constituents and antiinflammatory activities of Maqian (Zanthoxylum
In this study, 44 compounds in the petroleum ether extract of Maqian (Zanthoxylum myriacanthum var. pubescens) bark, a ... Chemical constituents and anti-inflammatory activities of Maqian (Zanthoxylum myriacanthum var. pubescens) bark extracts.pdf. ... Chemical Constituents And Antiinflammatory Activities Of Maqian (zanthoxylum Myriacanthum Var. Pubescens) Bark Extracts[J]. ... Chemical constituents and antiinflammatory activities of Maqian (Zanthoxylum myriacanthum var. pubescens) bark extracts. ...
  http://ir.xtbg.org.cn/handle/353005/10341
*  Zanthoxylum americanum | MTPR
November 16th & 18th, 2013: The leaves, bark (sans thorns), root bark and berries of Prickly Ash are medicinal, soothing sore throat and skin inflammation, increasing saliva, and improving blood flow and digestion. North Americans used it to numb toothache.. http://www.floradelaterre.com/. ...
  http://mtpr.org/term/zanthoxylum-americanum
*  Tropicos | Name - !Zanthoxylum L.
Shrubs or trees, often prickly. Leaves alternate, imparipinnate, glandular-punctate. Flowers mostly unequal, in axillary or terminal cymes. Calyx 3-8-lobed or absent. Petals 3-5, occasionally absent. Stamens 3-8, rudimentary in the female flowers. Ovary 1-5-locular; style sublateral, free or united above; stigma capitate. Fruit a schizocarp, subglobose ...
  http://www.tropicos.org/Name/40028189?projectid=32
*  A plant (Zanthoxylum… | Wellcome Collection
A plant (Zanthoxylum rhetsea) related to knobthorn: branch with flowers and fruit, separate flowers and fruit and sectioned ... A plant (Zanthoxylum rhetsea) related to knobthorn: branch with flowers and fruit, separate flowers and fruit and sectioned ...
  https://wellcomecollection.org/works/z9vg7f54
*  Evaluation of Ethnopharmacological and Antioxidant Potential of Zanthoxylum armatum DC.
Zanthoxylum armatum DC. (syn. Z. alatum Roxb.) is an important medicinal plant commonly called Timur or Indian prickly ash. The ... Evaluation of Ethnopharmacological and Antioxidant Potential of Zanthoxylum armatum DC.. Rabia Kanwal, Muhammad Arshad, Yamin ... Results obtained through different tests confirmed redox protective activities of Zanthoxylum armatum. Further in vitro and in ...
  https://www.hindawi.com/journals/jchem/2015/925654/abs/
*  Zanthoxylum coriaceum (SV6) :: Swingle Plant Anatomy Digital Archive
Digitized images of microscopic slices of Zanthoxylum coriaceum (SV6) plant structures that were stained and permanently ...
  http://merrick.library.miami.edu/cdm/compoundobject/collection/swingle/id/1658/rec/6827
*  Effects of Oils and Essential Oils from Seeds of Zanthoxylum schinifolium against Foodborne Viral Surrogates
M. S. Chung, "Volatile compounds of Zanthoxylum piperitum A.P. DC," Food Science and Biotechnology, vol. 14, pp. 529-532, 2005. ... Effects of Oils and Essential Oils from Seeds of Zanthoxylum schinifolium against Foodborne Viral Surrogates. Mi Oh and Mi Sook ... G. Wu and H. Wu, "Analgesia synergism of essential oil from pericarp of Zanthoxylum schinifolium and verapamil," Evidence-Based ... Seeds and pericarp of Zanthoxylum schinifolium, which belongs to the Rutaceae family, are widely consumed in Korea, China, and ...
  https://www.hindawi.com/journals/ecam/2014/135797/
*  Zanthoxylum - Wikipedia
Zanthoxylum anison L.O. Williams Zanthoxylum anodynum Ant.Molina Zanthoxylum apiculatum (Sandwith) P.G.Waterm. Zanthoxylum ... Zanthoxylum gardneri Engl. Zanthoxylum gilletii (De Wild.) P.G.Waterm. Zanthoxylum glomeratum C.C. Huang Zanthoxylum ... Zanthoxylum stipitatum C.C. Huang Zanthoxylum subspicatum H. Perrier Zanthoxylum syncarpum Tul. Zanthoxylum taediosum A. Rich. ... Zanthoxylum calcicola C.C. Huang Zanthoxylum capense (Thunb.) Harv. Zanthoxylum caribaeum Lam. - Yellow prickly ash Zanthoxylum ...
  https://en.wikipedia.org/wiki/Zanthoxylum
*  Zanthoxylum caribaeum - Wikipedia
Zanthoxylum caribaeum is a species of plant in the Rutaceae family. It is found in Belize, Guatemala, and Honduras. " ... "Zanthoxylum caribaeum Lam". World Checklist of Selected Plant Families (WCSP). Royal Botanic Gardens, Kew. Retrieved 29 ... Zanthoxylum gentlei. 2006 IUCN Red List of Threatened Species. Downloaded on 24 August 2007.. ...
  https://en.wikipedia.org/wiki/Zanthoxylum_caribaeum
*  Zanthoxylum delagoense - Wikipedia
Zanthoxylum delagoense is a species of plant in the Rutaceae family. It is endemic to Mozambique. Matimele, H.A.; Raimondo, D ... Zanthoxylum delagoense. 2006 IUCN Red List of Threatened Species. Downloaded on 24 August 2007.. ... Bandeira, S.; Burrows, J.E.; Darbyshire, I.; Massingue, A.O. & Timberlake, J. (2016). "Zanthoxylum delagoense". The IUCN Red ...
  https://en.wikipedia.org/wiki/Zanthoxylum_delagoense
*  Zanthoxylum chevalieri - Wikipedia
Zanthoxylum chevalieri is a species of plant in the Rutaceae family. It is endemic to Ghana. It is threatened by habitat loss. ... Hawthorne, W. (1998). "Zanthoxylum chevalieri". The IUCN Red List of Threatened Species. IUCN. 1998: e.T34830A9892724. doi: ...
  https://en.wikipedia.org/wiki/Zanthoxylum_chevalieri
*  Zanthoxylum schinifolium - Wikipedia
Zanthoxylum schinifolium, also called mastic-leaf prickly ash, is a species of flowering plant in the Rutaceae, the citrus ... "Zanthoxylum schinifolium". Germplasm Resources Information Network (GRIN). Agricultural Research Service (ARS), United States ... Dianxiang Zhang and Thomas G. Hartley (2008), "Zanthoxylum schinifolium", Flora of China online, 11, retrieved 7 May 2015 ...
  https://en.wikipedia.org/wiki/Zanthoxylum_schinifolium
*  Zanthoxylum harrisii - Wikipedia
Zanthoxylum harrisii is a species of plant in the Rutaceae family. It is endemic to Jamaica. It is threatened by habitat loss. ... Kelly, D.L. (1998). "Zanthoxylum harrisii". The IUCN Red List of Threatened Species. IUCN. 1998: e.T34311A9857406. doi:10.2305/ ...
  https://en.wikipedia.org/wiki/Zanthoxylum_harrisii
*  Zanthoxylum dipetalum - Wikipedia
Zanthoxylum dipetalum is a rare species of tree in the citrus family and in the same genus as Szechuan pepper. It is known by ... Zanthoxylum dipetalum var. tomentosum. Archived June 27, 2014, at the Wayback Machine. 2011 IUCN Red List of Threatened Species ... Zanthoxylum dipetalum. Archived August 29, 2011, at the Wayback Machine. Center for Plant Conservation. Fish, F., et al. (1975 ... Portner, T., Keir, M., Gon, S.M., Sporck-Koehler, M., Chau, M., Caraway, V.L. & Kwon, J. (2015). "Zanthoxylum dipetalum". The ...
  https://en.wikipedia.org/wiki/Zanthoxylum_dipetalum
*  Zanthoxylum integrifoliolum - Wikipedia
Zanthoxylum integrifoliolum is a species of plant in the Rutaceae family. It is found in the Philippines and Taiwan. World ... Conservation Monitoring Centre (1998). "Zanthoxylum integrifoliolum". The IUCN Red List of Threatened Species. IUCN. 1998: e. ...
  https://en.wikipedia.org/wiki/Zanthoxylum_integrifoliolum
*  Zanthoxylum nadeaudii - Wikipedia
Zanthoxylum nadeaudii is a species of plant in the Rutaceae family. It is endemic to French Polynesia. Florence, J. (1998). " ... "Zanthoxylum nadeaudii". The IUCN Red List of Threatened Species. IUCN. 1998: e.T38981A10155875. doi:10.2305/IUCN.UK.1998.RLTS. ...
  https://en.wikipedia.org/wiki/Zanthoxylum_nadeaudii
*  Zanthoxylum thomasianum - Wikipedia
Zanthoxylum thomasianum, also known as the St. Thomas prickly-ash, is a species of plant in the Rutaceae family. It is found in ... John listed as "endangered". Some taxonomers consider it a subspecies of Zanthoxylum punctatum. Clubbe, C.; Pollard, B.; Smith- ... Abbott, J.; Walker, R. & Woodfield, N. (2003). "Zanthoxylum thomasianum". IUCN Red List of Threatened Species. Version 2006. ...
  https://en.wikipedia.org/wiki/Zanthoxylum_thomasianum
*  Zanthoxylum albuquerquei - Wikipedia
Zanthoxylum albuquerquei is a species of tree in the Rutaceae family. It is endemic to Peru. Trees up to 27 m tall; trunk up to ... "Zanthoxylum albuquerquei". www.iucnredlist.org. Retrieved 2017-10-26. Simpson, D. (1982). "New species from South America III ...
  https://en.wikipedia.org/wiki/Zanthoxylum_albuquerquei
*  Zanthoxylum coriaceum - Wikipedia
Zanthoxylum coriaceum. NatureServe. Zanthoxylum coriaceum. Archived October 26, 2011, at the Wayback Machine. Center for Plant ... Zanthoxylum coriaceum is a species of flowering plant in the citrus family known by the common name Biscayne prickly-ash. It is ...
  https://en.wikipedia.org/wiki/Zanthoxylum_coriaceum
*  Zanthoxylum negrilense - Wikipedia
Zanthoxylum negrilense is a species of plant in the Rutaceae family. It is endemic to Jamaica. Kelly, D.L. (1998). "Zanthoxylum ...
  https://en.wikipedia.org/wiki/Zanthoxylum_negrilense

(1/36) Antibacterial and antifungal activities of extracts of Zanthoxylum chalybeum and Warburgia ugandensis, Ugandan medicinal plants.

Measles is a killer disease of children in Uganda. The treatment of the disease is mainly directed at the secondary microbial infections. A large proportion of the population in Uganda still relies on the use of herbal remedies, which have been claimed to produce beneficial responses. In this study, the efficacy of Warburgia ugandensis and Zanthoxylum chalybeum against common bacteria and fungi was investigated. Bactericidal and antifungal assays were done using extracts derived from Z. chalybeum and W. ugandensis (agar well diffusion, disc diffusion and colony count assays). All extracts (ethanolic, petroleum ether and aqueous) of Z. chalybeum did not show antimicrobial activity. Phytochemical investigations of Zanthoxylum chalybeum (seed) yielded a pure crystalline alkaloid (27-135 D) which was characterized as skimianine based on (1)H-NMR spectroscopy and comparison with spectra of authentic samples. Skimmianine did not have antimicrobial activity in this test system. W. ugandensis water extracts elicited antibacterial activity against both Escherischia coli and Staphylococcus aureus in the agar well assay but not in the disc diffusion assay. Warburgia ugandensis water extracts and fraction 27-163 D also showed antifungal activity against Candida albicans. Chromatography of extracts of Warburgia ugandensis stem bark afforded compound 49-169 K, which was characterized as the sesquiterpine muzigadial (by (1)H-NMR spectroscopy), which did not show antibacterial activity but had antifungal activity against C. albicans. Therefore, the claimed efficacy of W. ugandensis could be attributable to antibacterial and antifungal activity of its components. Since Z. chalybeum extracts had neither antifungal nor antibacterial activities, its mode of action is unclear from these results.  (+info)

(2/36) Effect of methanol extract of Zanthoxylum piperitum leaves and of its compound, protocatechuic acid, on hepatic drug metabolizing enzymes and lipid peroxidation in rats.

The effect of methanol extract and protocatechuic acid from the leaves of Zanthoxylum piperitum on lipid peroxidation and drug metabolizing enzymes were investigated in the liver of bromobenzene-treated rats. The methanol extract and protocatechuic acid reduced the level of lipid peroxide induced by bromobenzene. The methanol extract and protocatechuic acid reduced the activity of aniline hydroxylase that had been increased by bromobenzene, while did not affect the activities of aminopyrine N-demethylase and glutathione S-transferase. The methanol extract and compound effectively restored the activity of epoxide hydrolase which had been decreased by bromobenzene. These results may suggest that the methanol extract of Z. piperitum and protocatechuic acid prevented lipid peroxidation by reducing the activity of aniline hydroxylase, an epoxide-producing enzyme, and by enhancing the activity of epoxide hydrolase, an epoxide-removing enzyme, in rats that had been intoxicated with bromobenzene.  (+info)

(3/36) Acute toxicity effects of the methanolic extract of Fagara zanthoxyloides (Lam.) root-bark.

BACKGROUND: Fagara zanthoxyloides is a well known medicinal plant in Uganda. It is used extensively in malaria and other infections. However nothing is known about its toxicity. OBJECTIVE: The objective of the study was to evaluate the acute toxicity of the methanolic extract of the root-bark of F. zanthoxyloides, in mice. METHODS: Methanolic extract of the root-bark of the plant was administered orally to mice at various dose levels to determine the acute toxic effects and the median lethal dose (LD50) in mice. RESULTS: The LD50 of the methanolic extract was found to be 5.0 g/Kg body weight within 95% confidence limits. The mice showed signs of cerebral irritation before dying. Histopathological examinations of the viscera showed congestion and focal necrosis of the liver and renal tubules. CONCLUSION: It was concluded that the extract of F. zanthoxyloides is safe, however the cerebral mechanism that lead to the death of the mice need to be investigated further.  (+info)

(4/36) Evaluation of botanicals as repellents against mosquitoes.

Repellent properties of three plant extracts--essential oil (steam distillate) of Zanthoxylum limonella (fruits), Citrus aurantifolia (leaf) and petroleum ether extract of Z. limonella (fruits) were evaluated as repellent against Aedes (S.) albopictus mosquitoes in mustard (Dhara) and coconut (Parachute) oil base under laboratory conditions. Three concentrations--10, 20 and 30% of the repellents were evaluated. Repellents in mustard oil afforded longer protection time against the bites of Aedes (S.) albopictus mosquitoes than those in coconut oil. At 30% concentration, 296-304 min protection time was achieved by the test repellents in mustard oil base while repellents in coconut oil exhibited 223.5-245 min protection time at the same concentration. Oil of Z. limonella gave the highest protection time against the bites of Aedes (S.) albopictus mosquitoes at all the concentrations than other herbal repellents tested both in mustard and coconut oil.  (+info)

(5/36) Tyrosinase inhibitor isolated from the leaves of Zanthoxylum piperitum.

Two flavonols, quercetin (1) and quercitrin (2), were isolated from the leaves of Zanthoxylum piperitum. Their structures were established by UV, one- and two-dimensional NMR, and mass spectroscopic methods. Quercetin showed significant inhibition against mushroom tyrosinase with an IC50 value of 3.8 microg/ml, and appeared to inhibit the polyphenol oxidase activity of tyrosinase in a competitive manner (Ki = 10 +/- 0.20 microM) when L-tyrosine was used as a substrate, although it did not inhibit the melanin production of Streptomyces bikiniensis.  (+info)

(6/36) The essential oils from Zanthoxylum schinifolium pericarp induce apoptosis of HepG2 human hepatoma cells through increased production of reactive oxygen species.

The volatile extract from dried pericarp of Zanthoxylum schinifolium that was obtained by simultaneous distillation with dichloromethane and water was composed of 29.9% geranyl acetate, 15.8% citronella, 15.4% sabinene and the minor volatile components included beta-myrcene, linalool, (-)-isopulegol, citronellyl acetate, 1,4-dimethyl pyrazole, alpha-terpinene, 3-methyl-6-(1-methylethyl)-2-cyclo-hexene-1-o1 and trans-geraniol. The volatile extract decreased the cell viability and induced apoptotic death in HepG2 human hepatoma cells in a concentration- and time-related manner. In addition, the volatile extract increased the production of reactive oxygen species in a dose-dependent manner. Pretreatment of the cells with Trolox, a well-known antioxidant, significantly suppressed the generation of reactive oxygen species and cell death induced by the extract. However, caspase-3 activity was not changed in the extract-treated cells, suggesting that the extract-induced apoptosis of HepG2 cells is caspase-3 independent. Furthermore, in nude mice inoculated with Huh-7 human hepatoma cells, the extract significantly inhibited tumor development. These results suggest that the volatile extract from Zanthoxylum schinifolium pericarpium is a good candidate for hepatocellular carcinoma (HCC) therapy and that reactive oxygen species are the key signaling molecules in the volatile extract-induced cell death in HepG2 cells.  (+info)

(7/36) Sichuan pepper extracts block the PAK1/cyclin D1 pathway and the growth of NF1-deficient cancer xenograft in mice.

There is increasing evidence that more than 70% of cancers including pancreatic, breast and prostate cancers as well as neurofibromatosis (NF) are highly addicted to abnormal activation of the Ser/Thr kinase PAK1 for their growth. So far FK228 is the most potent among the HDAC (histone deacetylase) inhibitors that block the activation of both PAK1 and another kinase AKT, downstream of PI-3 kinase. However, FK228 is still in clinical trials (phase 2) for a variety of cancers (but not for NF as yet), and not available for most cancer/NF patients. Thus, we have been exploring an alternative which is already in the market, and therefore immediately useful for the treatment of those desperate cancer/NF patients. Here we provide the first evidence that extracts of Chinese/ Japanese peppercorns (Zanthoxyli Fructus) from the plant Zanthoxylum piperitum called "Hua Jiao"/"Sansho", block selectively the key kinase PAK1, leading to the downregulation of cyclin D1. Unlike FK228, these extracts do not inhibit AKT activation at the concentrations that block either cancer growth or PAK1 activation. The Chinese pepper extract selectively inhibits the growth of NF1-deficient malignant peripheral nerve sheath tumor (MPNST) cells, without affecting the growth of normal fibroblasts, and suppresses the growth of NF1-deficient human breast cancer (MDA-MB-231) xenograft in mice. Our data suggest that these peppercorn extracts would be potentially useful for the treatment of PAK1-dependent NF such as MPNST, in addition to a variety of PAK1-dependent cancers including breast cancers.  (+info)

(8/36) Polyphenolic constituent structures of Zanthoxylum piperitum fruit and the antibacterial effects of its polymeric procyanidin on methicillin-resistant Staphylococcus aureus.

Zanthoxylum piperitum (Rutaceae) is used as a spice and a natural medicine in Japan. Our study found that ZP-CT-A, a polymeric proanthocyanidin purified from the fruit of this species, noticeably decreased the minimum inhibitory concentrations of beta-lactam antibiotics for methicillin-resistant Staphylococcus aureus (MRSA). The structure of ZP-CT-A was characterized on the basis of (13)C NMR and size exclusion chromatographic data and the results of thiolytic degradation. A mechanistic study of the effects of ZP-CT-A indicated that it suppressed the activity of beta-lactamase and largely decreased the stability of the bacterial cell membrane of MRSA, as shown by a reduction in the tolerance of MRSA to low osmotic pressure and high ionic strength solutions.  (+info)



  • schinifolium
  • Here, we determined the antiviral activities of oils from seeds of Zanthoxylum schinifolium (ZSO) against foodborne viral surrogates, feline calicivirus-F9 (FCV-F9), and murine norovirus-1 (MNV-1), using plaque assay. (hindawi.com)
  • alatum
  • The essential oil obtained from the fresh leaves of Zanthoxylum alatum was analysed by gas chromatography/mass spectrometry (GC/MS). Fourteen components were identified, and linalool (30.58%), 2-decanone (20.85%), β -fenchol (9.43%), 2-tridecanone (8.86%), β -phellandrene (5.99%), Sabinene (4.82%), and α -pinene (4.11%) were the main components. (hindawi.com)
  • Good nematicidal activity against B. xylophilus was achieved with essential oils of Gaultheria fragrantissima and Zanthoxylum alatum . (brillonline.com)
  • Extracts
  • We investigated the applicability of extracts from Oenanthe javanica (OJ), Perilla frutescens (PF), and Zanthoxylum piperitum (ZP) as cosmetic ingredients by confirming their anti-oxidant and anti-inflammatory effects in vitro . (e-ajbc.org)