A severe form of LEPTOSPIROSIS, usually caused by LEPTOSPIRA INTERROGANS SEROVAR ICTEROHAEMORRHAGIAE and occasionally other serovars. It is transmitted to humans by the rat and is characterized by hemorrhagic and renal symptoms with accompanying JAUNDICE.
A condition characterized by a series of interrelated digital symptoms and joint changes of the lesser digits and METATARSOPHALANGEAL JOINTS of the FOOT. The syndrome can include some or all of the following conditions: hammer toe, claw toe, mallet toe, overlapping fifth toe, curly toe, EXOSTOSIS; HYPEROSTOSIS; interdigital heloma, or contracted toe.
Pain in the region of the METATARSUS. It can include pain in the METATARSAL BONES; METATARSOPHALANGEAL JOINT; and/or intermetatarsal joints (TARSAL JOINTS).
The five long bones of the METATARSUS, articulating with the TARSAL BONES proximally and the PHALANGES OF TOES distally.
The articulation between the head of one phalanx and the base of the one distal to it, in each toe.
The surgical cutting of a bone. (Dorland, 28th ed)

Three cases of canine leptospirosis in Quebec. (1/75)

Three dogs from different locations with acute renal failure were hospitalized in autumn 1996 and 1997. Leptospira interrogans serovar pomona was detected by the microscopic agglutination test. All dogs recovered after antibiotic treatment. The importance of the development of vaccines adapted to emerging serovars in dogs should be addressed.  (+info)

Expression in Escherichia coli of flaB, the gene coding for a periplasmic flagellin of Leptospira interrogans serovar pomona. (2/75)

A periplasmic flagellin gene, flaB, of Leptospira interrogans serovar pomona (strain Pomona) was expressed in Escherichia coli for the production and antigenic characterisation of the protein. The flaB structural gene, which was previously cloned into pUC118, was derived by PCR from the recombinant plasmid and used to generate an expression construct with the trc promoter-driven pProEx HT system. Under the conditions employed, the flaB was expressed as inclusion bodies formed within E. coli, yielding c. 120 mg of the recombinant protein/L of culture. A polyhistidine tag introduced at the amino-acid terminus of the FlaB protein allowed for the purification of the protein by nickel-chelate affinity chromatography. The expressed protein reacted with both mouse and bovine antisera to L. interrogans on Western blots, indicating that it could be of use in the diagnosis of leptospirosis. The recombinant leptospiral flagellin may also be of value in studying its role in the pathogenesis of leptospirosis.  (+info)

Risk factors for death and changing patterns in leptospirosis acute renal failure. (3/75)

The risk factors for death and changes in clinical patterns in leptospirosis (Weil's disease) have not been well studied. We retrospectively studied 110 patients with Weil's disease hospitalized in Brazil between 1985 and 1996. Univariate statistical analysis showed that nonsurvivors were older than survivors, and had higher frequency of oliguria, cardiac arrhythmia, dyspnea, and pulmonary rales. Logistic regression showed that the only independent factor associated with death was oliguria (odds ratio [OR] = 8.98). The presence of arthralgia (OR = 4.71), dehydration (OR = 6.26), dyspnea (OR = 17.7), and pulmonary rales (OR = 9.91) increased after 1994. These data suggest that in Weil's disease the clinical patterns have changed and the presence of oliguria is a risk factor for death.  (+info)

Leptospirosis - an under-diagnosed clinical condition. (4/75)

Leptospirosis is a zoonotic disease caused by leptospiral spirochaete. Two cases in children are described presenting with hepatorenal dysfunction.  (+info)

Identification of new repetitive element in Leptospira interrogans serovar copenhageni and its application to PCR-based differentiation of Leptospira serogroups. (5/75)

A new repetitive DNA element was identified in an isolate of Leptospira interrogans serovar copenhageni from a patient in Salvador, Brazil. A Sau3A genomic library from this strain was constructed and screened for repetitive DNA elements. An insert of 438 bp (Rep1) from one library clone hybridized to multiple chromosomal DNA fragments resolved electrophoretically after digestion with BamHI, HindIII, and MfeI. A single oligonucleotide primer, designated iRepl, was designed to generate multiple PCR amplicons of various electrophoretic mobilities in a PCR typing method. The method distinguished strains belonging to the eight pathogenic and three saprophytic species of the genus Leptospira. Clinical isolates obtained during urban epidemics between 1996 and 1998 in Salvador, Brazil, were analyzed by this PCR method. Although the iRep1 primer was unable to discriminate strains among L. interrogans serovar copenhageni isolates, it was able to differentiate strains belonging to different species and serogroups of Leptospira identified in Salvador. This PCR-based method may provide a faster and less expensive alternative to serologic tests used in reference laboratories.  (+info)

Competitive enzyme-linked immunosorbent assay for detection of Leptospira interrogans serovar pomona antibodies in bovine sera. (6/75)

A competitive enzyme-linked immunosorbent assay (ELISA) using a specific monoclonal antibody (M898) was developed for detection of bovine antibodies to Leptospira interrogans serovar pomona. This assay was evaluated using field sera (n = 190) with serovar pomona microscopic agglutination test (MAT) titers of > or =100 as the positive population (group A); field sera (n = 1,445) which were negative in the MAT (1:100 dilution) for serovar pomona (group B); and sera (from a specific-pathogen-free cattle herd [n = 210]) which were negative in the MAT (1:100 dilution) for serovars canicola, copenhageni, grippotyphosa, hardjo, pomona, and sejroe (group C). At the cutoff point recommended by receiver operating characteristic (ROC) curve analysis of the combined ELISA results of serum groups A, B, and C, the sensitivity and specificity values were 93.7 and 96.3%, respectively. The value for the area under this ROC curve was 0.977, indicating a high level of accuracy for the ELISA. Similar results were obtained from the analysis of the combined results of serum groups A and B and from the analysis of the combined results of serum groups A and C.  (+info)

First isolation of Leptospira fainei serovar Hurstbridge from two human patients with Weil's syndrome. (7/75)

Leptospira fainei serovar Hurstbridge is a recently discovered Leptospira species and so far it has only been cultured from animal sources. Based on positive serology and positive PCR for L. fainei among patients suspected of having leptospirosis, a role in human disease seems likely. This study describes two patients with Weil's disease from whom L. fainei was cultured. A local source of the infections was suspected, as these two patients resided in the same area of Denmark, were hospitalised approximately at the same time and had not been travelling recently. The Leptospira species was determined by serology, PCR and sequencing of bacterial DNA. One patient developed autoimmune hepatitis in the course of the L. fainei infection and was treated with both antibiotics and immunosuppression with good effect. The other patient had a self-limiting disease and did not receive any treatment.  (+info)

Identification of the hemolysis-associated protein 1 as a cross-protective immunogen of Leptospira interrogans by adenovirus-mediated vaccination. (8/75)

New vaccine strategies are needed for the prevention of leptospirosis, a widespread human and animal disease caused by pathogenic leptospires. Our previous work determined that a protein leptospiral extract conferred cross-protection in a gerbil model of leptospirosis. The 31- to 34-kDa protein fraction of Leptospira interrogans serovar autumnalis was shown sufficient for this purpose. In the present study, N-terminal sequencing of a 32-kDa fraction and Southern blotting of genomic DNA with corresponding degenerated oligonucleotide probes identified two of its constituents: hemolysis-associated protein 1 (Hap1) and the outer membrane Leptospira protein 1 (OmpL1). Adenovirus-mediated Hap1 vaccination induces significant protection against a virulent heterologous Leptospira challenge in gerbils, whereas a similar OmpL1 construct failed to protect the animals. These data indicate that Hap1 could be a good candidate for developing a new generation of vaccines able to induce broad protection against leptospirosis disease.  (+info)

Weil's disease is a severe form of leptospirosis, a bacterial infection caused by the spirochete Leptospira interrogans. It is named after the German physician Adolf Weil, who first described it in 1886. Weil's disease is characterized by the triad of symptoms: severe jaundice, kidney failure, and bleeding. The infection typically occurs through exposure to contaminated water or soil that has been contaminated with the urine of infected animals, such as rodents. The bacteria enter the body through cuts in the skin, mucous membranes, or via ingestion. Weil's disease is a medical emergency and requires prompt treatment with antibiotics to prevent severe complications and death.

Hammertoe syndrome, also known as hammer toe, is a deformity of the second, third, or fourth smaller toes where they become permanently bent at the middle joint, resembling a hammer. This condition can cause pain and difficulty walking, especially when wearing shoes that rub against the raised portion of the toe. Hammertoe syndrome can be caused by factors such as inherited foot type, arthritis, and muscle imbalance, and it can also result from wearing narrow or ill-fitting shoes for extended periods. Treatment options may include changes in footwear, orthotics, physical therapy, and in severe cases, surgery.

Metatarsalgia is a general term used to describe pain and inflammation in the ball of the foot (the metatarsal region). This is often caused by excessive pressure or stress on the metatarsal heads, usually due to factors such as poor foot mechanics, high-impact activities, or ill-fitting shoes. The pain can range from mild discomfort to sharp, intense sensations, and may be accompanied by symptoms like tingling, numbness, or burning in the toes. It's important to note that metatarsalgia is not a specific diagnosis but rather a symptom of an underlying issue, which should be evaluated and treated by a healthcare professional.

The metatarsal bones are a group of five long bones in the foot that connect the tarsal bones in the hindfoot to the phalanges in the forefoot. They are located between the tarsal and phalangeal bones and are responsible for forming the arch of the foot and transmitting weight-bearing forces during walking and running. The metatarsal bones are numbered 1 to 5, with the first metatarsal being the shortest and thickest, and the fifth metatarsal being the longest and thinnest. Each metatarsal bone has a base, shaft, and head, and they articulate with each other and with the surrounding bones through joints. Any injury or disorder affecting the metatarsal bones can cause pain and difficulty in walking or standing.

A toe joint, also known as a metatarsophalangeal (MTP) joint, is the articulation between the bones in the foot (metatarsals) and the bones in the toes (phalanges). There are five MTP joints in each foot, one for each toe except for the big toe, which has its own separate joint called the first metatarsophalangeal joint.

The MTP joints allow for movement and flexibility of the toes, enabling activities such as walking, running, and standing. Problems with these joints can lead to pain, stiffness, and difficulty moving, making it important to maintain their health and mobility through proper foot care and exercise.

Osteotomy is a surgical procedure in which a bone is cut to shorten, lengthen, or change its alignment. It is often performed to correct deformities or to realign bones that have been damaged by trauma or disease. The bone may be cut straight across (transverse osteotomy) or at an angle (oblique osteotomy). After the bone is cut, it can be realigned and held in place with pins, plates, or screws until it heals. This procedure is commonly performed on bones in the leg, such as the femur or tibia, but can also be done on other bones in the body.

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Factors associated with thrombocytopenia in severe leptospirosis (Weils disease) Authors. * Elizabeth F. Daher Federal ... All patients had a diagnosis of severe leptospirosis (Weils disease). Acute kidney injury was defined according to the RIFLE ... Lengthy disease and acute kidney injury are risk factors for thrombocytopenia. There was no significant association between ... 7.5%, p = 0.005). The independent risk factors associated with thrombocytopenia during the hospital stay were lengthy disease ( ...
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Learn about other conditions that can cause heel pain at Weil Foot & Ankle Institute. ... Meet Weil Foot & Ankle Institute. Weil Foot & Ankle Institute was founded in 1965, by Dr. Lowell Weil Sr, who was inspired by a ... While typically this disease presents with pain in the small joints of the hands and feet, it can also cause heel pain. The ... Pagets Disease: This is a chronic condition of the bone that causes osteoclast (bone-absorbing) activity to be more active ...
Leptospirosis (Weils Disease). It is important that all river users are familiar with the symptoms of this infection, which ... that take place near the waters edge where rat urine is more likely to be found increase the risk of contracting the disease. ...
HSE (n.d.) Leptospirosis (Weils Disease and Hardjo). Health and Safety Executive UK. ... Sanitation workers are at an increased risk of becoming ill from waterborne diseases.[19] One specific disease that concerns ... Centers for Disease Control and Prevention (September 29, 2020). "Guidance for Controlling Potential Risks to Workers Exposed" ... It is difficult to estimate the burden of disease for sanitation workers.[4] A systematic literature review with 65 studies ...
Adolf Weil (7 February 1848, Heidelberg - 23 July 1916, Wiesbaden) was a German physician after whom Weils disease is named. ... 1] Bibliography @ Who Named It JewishEncyclopedia.com - WEIL, ADOLF: at jewishencyclopedia.com Adolf Weil @ Who Named It. v t e ... Shortly after receiving news that Weils disease was caused by a spirochete, he died of acute hemoptysis. [ ... Weil studied medicine at the University of Heidelberg, and afterwards furthered his education in Berlin and Vienna. From 1872 ...
fifth disease. *traumatic brain injuries, such as concussion or subdural hematoma. *leptospirosis (Weils disease) ... severe liver or kidney disease, long-term starvation, and hormonal deficiencies. If you have diabetes, taking too much insulin ... http://www.mayoclinic.org/diseases-conditions/migraine-headache/home/ovc-20202432. *. MayoClinic Staff. (2018). Nausea and ... http://www.mayoclinic.org/diseases-conditions/hypoglycemia/basics/complications/con-20021103. *. MayoClinic Staff. (2018). ...
Weil disease; Icterohemorrhagic fever; Swineherds disease; Rice-field fever; Cane-cutter fever; Swamp fever; Mud fever; ... Weil disease, a severe form of leptospirosis, is rare in the continental United States. Hawaii has the highest number of cases ... Centers for Disease Control and Prevention. wwwnc.cdc.gov/travel/page/yellowbook-home. Updated May 1, 2023. Accessed May 17, ... Mandell, Douglas, and Bennetts Principles and Practice of Infectious Diseases. 9th ed. Philadelphia, PA: Elsevier; 2020:chap ...
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Half of the patients who died had the icteric form of the disease, 4 had the typical signs and symptoms of Weil disease, and 1 ... Weil disease was present in 27 (22%). In our case-series, jaundice appeared to be a common sign, in contrast to recent studies ... Bharti AR, Nally JE, Ricaldi JN, Matthias MA, Diaz MM, Lovett MA, Leptospirosis: a zoonotic disease of global importance. ... Clinical presentation varies from a flu-like syndrome to Weil disease, which includes jaundice, renal failure, and hemorrhagic ...
The Council is committed to the investigation and prevention of the spread of infectious diseases. ... Weils disease (Leptospirosis). Advice notes on each of these infectious diseases are available from the Infectious Diseases ... Infectious diseases North Kesteven District Council is committed to the investigation and prevention of the spread of ... The main infectious diseases reported to the team are:. * Food poisoning (salmonella species; campylobacter species; viral ...
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Myocarditis is an inflammatory disease of the myocardium with a wide range of clinical presentations, from subtle to ... Spirochetal: Syphilis, leptospirosis/Weil disease, relapsing fever/Borrelia, Lyme disease. * Fungal: Candidiasis, aspergillosis ... Systemic inflammatory disease: Giant cell myocarditis, sarcoidosis, Kawasaki disease, Crohn disease, systemic lupus ... Predictors of disease course in patients with acute myocarditis. Circulation. 2000 Dec 5. 102(23):2829-35. [QxMD MEDLINE Link] ...
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The worst form of leptospirosis, Weils disease, is typically linked to rat-transmitted bacteria. (8) ... At that point, the leptospirosis sickness is referred to as Weils disease. (6) ... Leptospirosis is a bacterial disease that spreads through direct contact with the urine of infected animals. The disease can ... However, the urine of an infected person is a potential source of the disease for someone else. Also rare but possible is an ...
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  • All patients had a diagnosis of severe leptospirosis (Weil's disease). (usp.br)
  • Weil disease, a severe form of leptospirosis, is rare in the continental United States. (medlineplus.gov)
  • Leptospirosis - a bacterial disease that causes serious illness by damaging vital organs such as the liver and kidneys. (pdsa.org.uk)
  • There is no titre test available for leptospirosis , so your dog will always need their yearly booster for this, even if their results show that they are protected for other diseases. (pdsa.org.uk)
  • Because both diseases are endemic to Greece and have similar clinical, epidemiologic, and seasonal characteristics ( 7 ), all samples sent to our laboratory for testing either for leptospirosis or for hantavirus infection are always tested for both ( 8 ). (cdc.gov)
  • Leptospirosis is a bacterial disease that spreads through direct contact with the urine of infected animals. (davidwolfe.com)
  • Accordingly, leptospirosis can sometimes be mistaken for another disease. (davidwolfe.com)
  • At that point, the leptospirosis sickness is referred to as Weil's disease. (davidwolfe.com)
  • Do not use wild rats as roughly 70% carry leptospirosis, sometimes called Weil's disease. (barnowltrust.org.uk)
  • Wild rats often carry leptospirosis or Weil's disease - a serious illness easily transmitted to humans. (barnowltrust.org.uk)
  • Leptospirosis, or Weil's disease, can be fatal to humans. (lichfielddc.gov.uk)
  • Leptospirosis may be difficult to diagnose because its initial symptoms are similar to many other diseases, and some cases have few to no symptoms, but early diagnosis is crucial, as successful treatment should be started within the first 4 days of illness. (logicalimages.com)
  • He's only half-joking: Weil's disease is a severe form of leptospirosis that causes headaches, chills and muscle aches, which you might contract if you came into contact with the urine, blood, or tissue of rodents that are infected with the bacteria. (yahoo.com)
  • Their urine carries a bacteria that leads to leptospirosis and then Weil's Disease, which can be fatal. (carpforum.co.uk)
  • More than a week after massive flooding from a southwest monsoon plagued Olongapo City, the number of cases of the bacterial disease, leptospirosis has gone up sharply to near 300 cases, according to a GMA News report today . (theglobaldispatch.com)
  • According to the report, at least 296 people have been diagnosed with leptospirosis, with eight deaths related to the disease. (theglobaldispatch.com)
  • Leptospirosis is a bacterial zoonotic disease caused by the corkscrew shaped organism, Leptospira. (theglobaldispatch.com)
  • Leptospirosis is an infectious disease of humans and animals that is caused by pathogenic spirochetes of the genus Leptospira . (medscape.com)
  • Salmonellosis, Weil's disease, leptospirosis and rat bite Typhoid fever are just some of the main rodent-borne diseases that can affect humans. (rentokil.com)
  • Although leptospirosis continues to be predominantly an occupational disease, in recent decades it has also increasingly been recognized as a disease of recreation. (medscape.com)
  • The term weil's disease is identified in base64 scheme by the sequence d2VpbCdzIGRpc2Vhc2U=, while the MD5 signature is equal to 9097d692de6ae178ee938814ff4c40d6. (altervista.org)
  • The ASCII encoding of weil's disease in hexadecimal notation is 7765696c27732064697365617365. (altervista.org)
  • Adolf Weil (7 February 1848, Heidelberg - 23 July 1916, Wiesbaden) was a German physician after whom Weil's disease is named. (wikipedia.org)
  • Shortly after receiving news that Weil's disease was caused by a spirochete, he died of acute hemoptysis. (wikipedia.org)
  • Weil's disease is carried by animals, and can be water-borne. (lowimpact.org)
  • Rats are known to spread infections such as Hantavirus, Salmonella, and Weil's disease. (horizonpestcontrol.com)
  • This phase is also called Weil's disease. (theglobaldispatch.com)
  • In humans, it is known as Weil's disease and symptoms include fever, muscle pains, vomiting and jaundice. (midwesternpestcontrol.com)
  • The Centers for Disease Control and Prevention (CDC) released data that covered the period from April to December of 2021, including both the delta surge and the first emergence of omicron, and noted that the rates of cases and deaths were consistently higher in all periods among those who were not vaccinated. (drweil.com)
  • Centers for Disease Control and Prevention. (medlineplus.gov)
  • Courtesy of the Centers for Disease Control and Prevention (CDC), Rob Weyant. (medscape.com)
  • These statistics are collected and compiled from reports sent by state health departments to the National Notifiable Diseases Surveillance System (NNDSS), which is operated by CDC in collaboration with the Council of State and Territorial Epidemiologists (CSTE). (cdc.gov)
  • Rodent borne diseases come in all shapes and sizes from bacteria-based illnesses such as salmonella to viruses such as hantavirus. (rentokil.ie)
  • Other diseases, such as toxoplasmosis and salmonella, affect both humans and animals. (lichfielddc.gov.uk)
  • Clinical presentation varies from a flu-like syndrome to Weil disease, which includes jaundice, renal failure, and hemorrhagic complications. (cdc.gov)
  • In our case-series, jaundice appeared to be a common sign, in contrast to recent studies in other countries in which the icteric form of the disease was observed in only 10% of cases ( 10 ). (cdc.gov)
  • The team receive numerous notifications of infectious disease, of which not all are cases of food poisoning. (n-kesteven.gov.uk)
  • The Highlights section presents information on selected nationally notifiable diseases to provide a context in which to interpret surveillance and disease-trend data and to provide further information on the epidemiology and prevention of selected diseases. (cdc.gov)
  • You can also catch a rodent-borne disease from inhaling dust that has been contaminated by their urine. (rentokil.ie)
  • Be aware that activities that can cause open wounds or that take place near the water's edge where rat urine is more likely to be found increase the risk of contracting the disease. (riverstourtrust.org)
  • You can catch these diseases by coming into direct contact with their urine, this can be by touching it or touching something that has been contaminated. (rentokil.ie)
  • However, the urine of an infected person is a potential source of the disease for someone else. (davidwolfe.com)
  • The Cola cans had traces of dried rat urine on them containing Weil s Disease and other toxic substances harmful to humans. (g7jjf.com)
  • The independent risk factors associated with thrombocytopenia during the hospital stay were lengthy disease (OR: 1.2, p = 0.001) and acute kidney injury (OR: 6.6, p = 0.004). (usp.br)
  • Lengthy disease and acute kidney injury are risk factors for thrombocytopenia. (usp.br)
  • Pulse-dose steroids may also play a role in the management of severe pulmonary disease. (medscape.com)
  • Comparison of comorbidities demonstrated that COVID-19-positive patients had higher rates of diabetes, heart failure, and pulmonary disease. (bvsalud.org)
  • Respiratory symptoms were recognized during the first phase of the disease, as other studies have reported ( 10 ). (cdc.gov)
  • We apply our methodology to China, Japan, and South Korea, and estimate the economic burden of chronic conditions in five domains (cardiovascular diseases, cancer, respiratory diseases, diabetes, and mental health conditions). (repec.org)
  • Rheumatoid Arthritis: This is an autoimmune disease that causes chronic inflammation that damages the structures around joints. (weil4feet.com)
  • Psoriatic Arthritis: This is another autoimmune disease that causes pain and swelling within joints. (weil4feet.com)
  • Proteinuric kidney diseases share an aggressive clinical course of developing end-stage renal disease. (karger.com)
  • Proteinuria is a major determinant of progression of chronic kidney disease (CKD), which is associated with more rapid worsening of renal function and earlier initiation of renal replacement therapy independent of estimated glomerular filtration rate (eGFR) [ 1 ]. (karger.com)
  • Half of the patients who died had the icteric form of the disease, 4 had the typical signs and symptoms of Weil disease, and 1 had central nervous system involvement. (cdc.gov)
  • Dogs are the pet most known to display clinical symptoms of the disease. (davidwolfe.com)
  • But by slapping Band-aids on symptoms rather than helping patients get at the root of why the symptoms are there in the first place, we put our patients at risk of more disease and even premature death. (wakeup-world.com)
  • This means that it is an early sign of the disease that develops before more obvious diagnosable symptoms appear. (medicalnewstoday.com)
  • Efforts to eliminate lymphatic filariasis have focused on massive treatment programs that involve administering medications to people living in areas where the disease is endemic, as a means of curing current infections and preventing new ones. (wustl.edu)
  • Because no cases of paralytic poliomyelitis, western equine encephalitis, or yellow fever were reported in the United States during 2001, these diseases do not appear in the tables in Part 1. (cdc.gov)
  • The disease begins multiplying, causing fever, headaches or general weakness. (midwesternpestcontrol.com)
  • Other possible conditions causing heel pain include crystal deposition arthritides, Paget's Disease, Diffuse idiopathic skeletal hyperostosis, Reiter's disease, diabetes, and sickle cell anemia. (weil4feet.com)
  • Graves disease is associated with pernicious anemia , vitiligo , diabetes mellitus type 1 , autoimmune adrenal insufficiency , systemic sclerosis , myasthenia gravis , Sjögren syndrome , rheumatoid arthritis , and systemic lupus erythematosus . (medscape.com)
  • Paget's Disease: This is a chronic condition of the bone that causes osteoclast (bone-absorbing) activity to be more active than osteoblast (bone-making) activity. (weil4feet.com)
  • We incorporate measures of disease prevalence into a human capital augmented production function, which enables us to determine the economic costs of chronic health conditions in terms of foregone gross domestic product (GDP). (repec.org)
  • The economic burden of chronic diseases: Estimates and projections for China, Japan, and South Korea ," Hohenheim Discussion Papers in Business, Economics and Social Sciences 09-2017, University of Hohenheim, Faculty of Business, Economics and Social Sciences. (repec.org)
  • The Economic Burden of Chronic Diseases: Estimates and Projections for China, Japan, and South Korea ," NBER Working Papers 23601, National Bureau of Economic Research, Inc. (repec.org)
  • Myocarditis is an inflammatory disease of the myocardium with a wide range of clinical presentations, from subtle to devastating. (medscape.com)
  • Early studies did suggest that statins are effective for men under 65 with pre-existing heart disease, but later, more rigorous clinical trials has not confirmed this benefit. (thehealthyskeptic.org)
  • Patients with severe disease should remain hospitalized until adequate resolution of organ failure and clinical infection. (medscape.com)
  • Vaccinations help protect against serious, potentially fatal diseases. (pdsa.org.uk)
  • Distemper - a very serious, often fatal disease that affects several different organs in the body including the guts, heart, immune system, lungs, brain and nerves. (pdsa.org.uk)
  • To provide clinicians with information on pathophysiology, early detection, disease monitoring, guidelines, and new and emerging treatments for PBC. (medscape.org)
  • In some patients, Graves disease represents a part of more extensive autoimmune processes leading to dysfunction of multiple organs (eg, polyglandular autoimmune syndromes ). (medscape.com)
  • Surgical outcomes in patients with Cushing's disease. (hopkinsmedicine.org)
  • We hypothesized that amiloride not triamterene (an analog of amiloride) would reduce proteinuria in the patients with proteinuric kidney disease. (karger.com)
  • Both amiloride and triamterene significantly reduced proteinuria in patients with proteinuric kidney disease. (karger.com)
  • As doctors, I believe it is our responsibility to dig into the lives of our patients so we can help them figure out what might be activating disease-causing stress responses in the body and what they might do to facilitate healing relaxation responses in the body. (wakeup-world.com)
  • Patients with severe disease should be placed on bed rest until adequately resuscitated and treated. (medscape.com)
  • Transfer to a facility with an appropriate level of care should be considered in patients with severe disease. (medscape.com)
  • Agency for Toxic Substances and Disease Registry. (cdc.gov)
  • Damage and Dysfunction, Agency for Toxic Substances and Disease Registry. (cdc.gov)
  • 2001. Public health assessment: Blackbird Mine, cobalt, Lemhi County, Idaho: Agency for Toxic Substances and Disease Registry. (cdc.gov)
  • Unlike previously adopted frameworks, this approach allows us to account for i) variations in human capital for workers in different age groups, ii) mortality and morbidity effects of non-communicable diseases, and iii) the treatment costs of diseases. (repec.org)
  • These references provide additional information on surveillance and epidemiologic issues, diagnostic issues, or disease control activities. (cdc.gov)
  • Phylogenetic Concepts and Tools Applied to Epidemiologic Investigations of Infectious Diseases. (cdc.gov)
  • Norway rats also carry bacteria and pathogens that can cause diseases. (a-z-animals.com)
  • Comparing the microbiome from healthy corals to those in early tissue necrosis suggests 21 potential pathogens, which might act as the promoters of such disease. (nature.com)
  • You can reduce your risk of developing diseases influenced by inflammation, including Alzheimer's, simply by following an anti-inflammatory diet like the one featured on the Dr. Weil on Healthy Aging online guide. (drweil.com)
  • Sanitation workers are at an increased risk of becoming ill from waterborne diseases. (wikipedia.org)
  • If you stop vaccinating your dog, they will be at risk of catching infectious diseases. (pdsa.org.uk)
  • The FDA has approved the prescription of statins to people at low risk for heart disease and stroke, who don't even have high cholesterol. (thehealthyskeptic.org)
  • Apart from the risk from cans and bottles the metal detectorist is exposed to the disease just by being on a field and handling the soil and vegetation when digging. (g7jjf.com)
  • Weil has studied lymphatic filariasis - which is caused by parasitic worms and spread by mosquitoes - for decades. (wustl.edu)
  • People in regions with lymphatic filariasis typically require treatment annually for five to seven years to reduce infection rates to levels that no longer support transmission of the disease by mosquitoes. (wustl.edu)
  • Mosquitoes are known to be carriers of dangerous diseases - such as malaria, dengue , Zika virus , Chikungunya - and businesses in regions with high mosquito density need to therefore ensure that their working environments in commercial premises have the suitable protection in place to keep employees safe. (rentokil.com)
  • Parvovirus - a highly contagious, potentially deadly disease that causes severe vomiting and diarrhoea. (pdsa.org.uk)
  • What happens when a deadly disease is eradicated? (cdc.gov)
  • Found worldwide, it was long considered an occupational disease (miners, farming, vets, and sugarcane harvesting and sewer workers), it is increasingly associated with recreational water sports and camping. (theglobaldispatch.com)
  • The infection can be treated with antibiotics (penicillin and doxycycline), especially if started early in the disease. (theglobaldispatch.com)
  • Low blood sugar can develop for a variety of reasons, including excessive alcohol consumption, medication side effect, severe liver or kidney disease , long-term starvation, and hormonal deficiencies. (healthline.com)
  • Because the dates of onset or diagnosis for notifiable diseases are not always reported, these surveillance data are presented by the year and week they were reported to CDC by public health officials in state and territorial health departments. (cdc.gov)
  • The annual incidence rate of the disease is 3 cases per 1 million population ( 6 ). (cdc.gov)
  • Part 1 contains tables showing incidence data for each of the diseases considered nationally notifiable during 2001. (cdc.gov)
  • Early detection of occupational diseases. (cdc.gov)
  • While we have made great strides in many countries, lymphatic filariasis remains pervasive in many impoverished countries in Africa and Asia, where it causes incredible suffering and disability," Weil said. (wustl.edu)
  • North Kesteven District Council is committed to the investigation and prevention of the spread of infectious diseases. (n-kesteven.gov.uk)
  • A notifiable disease is one for which regular, frequent, and timely information regarding individual cases is considered necessary for the prevention and control of the disease. (cdc.gov)
  • While typically this disease presents with pain in the small joints of the hands and feet, it can also cause heel pain. (weil4feet.com)
  • Nowadays, the infections that cause Reiter's are typically genitourinary or sexually transmitted diseases. (weil4feet.com)
  • [ 2 ] Moreover, advances in cancer immunotherapy with immune checkpoint inhibitors (anti-CTLA-4, anti-PD-1, and anti-PD-L1 antibodies) have led to immune-related adverse effects, including problems affecting the thyroid glands (ie, thyroiditis [typically with a transient hyperthyroid phase followed by a permanent hypothyroid phase] and Graves disease). (medscape.com)
  • His earlier research led to a new diagnostic test for the disease. (wustl.edu)
  • The mortality rate is about 40% for Weil disease and between 1%-5% overall. (logicalimages.com)
  • In 1999, mortality data began to be coded according to the International Statistical Classification of Diseases and Related Health Problems, Tenth Revision. (cdc.gov)
  • To bridge the mortality data for the period 1996-1998 (deaths coded using the International Classification of Diseases, Ninth Revision), and 1999, we use comparability ratios provided by the National Center for Health Statistics. (cdc.gov)
  • The subsequent investigation concluded that the disease had been contracted by her drinking out of a Cola can without washing the can before drinking the contents. (g7jjf.com)

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