Two off-spring from the same PREGNANCY. They are from a single fertilized OVUM that split into two EMBRYOS. Such twins are usually genetically identical and of the same sex.
Disorders affecting TWINS, one or both, at any age.
Two individuals derived from two FETUSES that were fertilized at or about the same time, developed in the UTERUS simultaneously, and born to the same mother. Twins are either monozygotic (TWINS, MONOZYGOTIC) or dizygotic (TWINS, DIZYGOTIC).
Two offspring from the same PREGNANCY. They are from two OVA, fertilized at about the same time by two SPERMATOZOA. Such twins are genetically distinct and can be of different sexes.
The division of a ZYGOTE into two parts, each of which is capable of further development.
Conjoined twins are a rare type of monozygotic twinning where genetically identical individuals form a single organism with varying degrees of physical connection and shared anatomy due to incomplete division during embryonic development.
Methods of detecting genetic etiology in human traits. The basic premise of twin studies is that monozygotic twins, being formed by the division of a single fertilized ovum, carry identical genes, while dizygotic twins, being formed by the fertilization of two ova by two different spermatozoa, are genetically no more similar than two siblings born after separate pregnancies. (Last, J.M., A Dictionary of Epidemiology, 2d ed)
Three individuals derived from three FETUSES that were fertilized at or about the same time, developed in the UTERUS simultaneously, and born to the same mother.
The condition of carrying TWINS simultaneously.
The study of the patterns of ridges of the skin of the fingers, palms, toes, and soles.
The condition of carrying two or more FETUSES simultaneously.
The external elements and conditions which surround, influence, and affect the life and development of an organism or population.
Four individuals derived from four FETUSES that were fertilized at or about the same time, developed in the UTERUS simultaneously, and born to the same mother.
The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
Five individuals derived from five FETUSES that were fertilized at or about the same time, developed in the UTERUS simultaneously, and born to the same mother.
Passage of blood from one fetus to another via an arteriovenous communication or other shunt, in a monozygotic twin pregnancy. It results in anemia in one twin and polycythemia in the other. (Lee et al., Wintrobe's Clinical Hematology, 9th ed, p737-8)
The outward appearance of the individual. It is the product of interactions between genes, and between the GENOTYPE and the environment.
Selective abortion of one or more embryos or fetuses in a multiple gestation pregnancy. The usual goal is to improve the outcome for the remaining embryos or fetuses.
A latent susceptibility to disease at the genetic level, which may be activated under certain conditions.
The combined effects of genotypes and environmental factors together on phenotypic characteristics.
An infant during the first month after birth.
The systems and processes involved in the establishment, support, management, and operation of registers, e.g., disease registers.
The different ways GENES and their ALLELES interact during the transmission of genetic traits that effect the outcome of GENE EXPRESSION.
The transfer of mammalian embryos from an in vivo or in vitro environment to a suitable host to improve pregnancy or gestational outcome in human or animal. In human fertility treatment programs, preimplantation embryos ranging from the 4-cell stage to the blastocyst stage are transferred to the uterine cavity between 3-5 days after FERTILIZATION IN VITRO.
The experimental study of the relationship between the genotype of an organism and its behavior. The scope includes the effects of genes on simple sensory processes to complex organization of the nervous system.
The transmission of traits encoded in GENES from parent to offspring.
The mass or quantity of heaviness of an individual at BIRTH. It is expressed by units of pounds or kilograms.
The occurrence in an individual of two or more cell populations of different chromosomal constitutions, derived from a single ZYGOTE, as opposed to CHIMERISM in which the different cell populations are derived from more than one zygote.
The aggregate of social and cultural institutions, forms, patterns, and processes that influence the life of an individual or community.
I'm sorry for any confusion, but "Denmark" is not a medical term and does not have a medical definition. It is a country located in northern Europe. If you have any questions related to medicine or health, I would be happy to try to help answer them.
Theoretical representations that simulate the behavior or activity of genetic processes or phenomena. They include the use of mathematical equations, computers, and other electronic equipment.
'Abnormalities, Multiple' is a broad term referring to the presence of two or more structural or functional anomalies in an individual, which may be genetic or environmental in origin, and can affect various systems and organs of the body.
A syndrome of defective gonadal development in phenotypic females associated with the karyotype 45,X (or 45,XO). Patients generally are of short stature with undifferentiated GONADS (streak gonads), SEXUAL INFANTILISM, HYPOGONADISM, webbing of the neck, cubitus valgus, elevated GONADOTROPINS, decreased ESTRADIOL level in blood, and CONGENITAL HEART DEFECTS. NOONAN SYNDROME (also called Pseudo-Turner Syndrome and Male Turner Syndrome) resembles this disorder; however, it occurs in males and females with a normal karyotype and is inherited as an autosomal dominant.
The performance of dissections, injections, surgery, etc., by the use of micromanipulators (attachments to a microscope) that manipulate tiny instruments.
The outermost extra-embryonic membrane surrounding the developing embryo. In REPTILES and BIRDS, it adheres to the shell and allows exchange of gases between the egg and its environment. In MAMMALS, the chorion evolves into the fetal contribution of the PLACENTA.
Sets of cell surface antigens located on BLOOD CELLS. They are usually membrane GLYCOPROTEINS or GLYCOLIPIDS that are antigenically distinguished by their carbohydrate moieties.
The techniques used to select and/or place only one embryo from FERTILIZATION IN VITRO into the uterine cavity to establish a singleton pregnancy.
A conflict occurring from 1954 through 1975 within the Republic of Vietnam. It involved neighboring nations and the United States and other members of the Southeast Asia Treaty Organization.
I'm sorry for any confusion, but "Sweden" is not a medical term and does not have a medical definition. It is a country located in Northern Europe. If you have any questions related to medical topics or definitions, I would be happy to try to help answer them!

Genetic influences on cervical and lumbar disc degeneration: a magnetic resonance imaging study in twins. (1/1447)

OBJECTIVE: Degenerative intervertebral disc disease is common; however, the importance of genetic factors is unknown. This study sought to determine the extent of genetic influences on disc degeneration by classic twin study methods using magnetic resonance imaging (MRI). METHODS: We compared MRI features of degenerative disc disease in the cervical and lumbar spine of 172 monozygotic and 154 dizygotic twins (mean age 51.7 and 54.4, respectively) who were unselected for back pain or disc disease. An overall score for disc degeneration was calculated as the sum of the grades for disc height, bulge, osteophytosis, and signal intensity at each level. A "severe disease" score (excluding minor grades) and an "extent of disease" score (number of levels affected) were also calculated. RESULTS: For the overall score, heritability was 74% (95% confidence interval [95% CI] 64-81%) at the lumbar spine and 73% (95% CI 64-80%) at the cervical spine. For "severe disease," heritability was 64% and 79% at the lumbar and cervical spine, respectively, and for "extent of disease," heritability was 63% and 63%, respectively. These results were adjusted for age, weight, height, smoking, occupational manual work, and exercise. Examination of individual features revealed that disc height and bulge were highly heritable at both sites, and osteophytes were heritable in the lumbar spine. CONCLUSION: These results suggest an important genetic influence on variation in intervertebral disc degeneration. However, variation in disc signal is largely influenced by environmental factors shared by twins. The use of MRI scans to determine the phenotype in family and population studies should allow a better understanding of disease mechanisms and the identification of the genes involved.  (+info)

High polymorphism level of genomic sequences flanking insertion sites of human endogenous retroviral long terminal repeats. (2/1447)

The polymorphism at the multitude of loci adjacent to human endogenous retrovirus long terminal repeats (LTRs) was analyzed by a technique for whole genome differential display based on the PCR suppression effect that provides selective amplification and display of genomic sequences flanking interspersed repeated elements. This strategy is simple, target-specific, requires a small amount of DNA and provides reproducible and highly informative data. The average frequency of polymorphism observed in the vicinity of the LTR insertion sites was found to be about 12%. The high incidence of polymorphism within the LTR flanks together with the frequent location of LTRs near genes makes the LTR loci a useful source of polymorphic markers for gene mapping.  (+info)

X-chromosome inactivation patterns do not implicate asymmetric splitting of the inner cell mass in the aetiology of twin-twin transfusion syndrome. (3/1447)

The aetiology of twin-twin transfusion syndrome (TTTS) is unclear. We investigated the hypothesis that monochorionic (MC) pregnancies with TTTS are associated with differences in the timing and symmetry of twinning compared to MC twin pregnancies without TTTS. DNA was extracted from the umbilical cord vessels of 26 female MC twins, 14 with and 12 without TTTS on serial antenatal ultrasound. X-inactivation patterns were determined by DNA digestion with Hhal and Hpall followed by polymerase chain reaction for a polymorphic trinucleotide repeat in the androgen receptor gene. Products were quantified by densitometry and results compared to those in peripheral blood samples of adult female controls. The median degree of non-random inactivation was similar in MC twins with TTTS, in MC twins without TTTS, and in adult controls. The percentage of individuals with skewed (> or =30/70%) inactivation patterns was no different in MC twins with TTTS compared to those without TTTS, and was similar to adult controls using either enzyme technique. In conclusion we found no difference in the degree or frequency of non-random X-inactivation patterns in TTTS. X-inactivation patterns do not appear to be a useful tool for studying the symmetry of inner cell mass splitting in monochorionic twins.  (+info)

Genetic determination of islet cell autoimmunity in monozygotic twin, dizygotic twin, and non-twin siblings of patients with type 1 diabetes: prospective twin study. (4/1447)

OBJECTIVE: To test the hypothesis that non-diabetic dizygotic and monozygotic twin siblings of patients with type 1 diabetes have a similar high prevalence of islet cell autoantibodies, thus suggesting that islet cell autoimmunity is mainly environmentally determined. DESIGN: Prospective twin study. SETTING: Two specialist centres for diabetes in the United States. PARTICIPANTS: Non-diabetic monozygotic twin (n=53), dizygotic twin (n=30), and non-twin (n=149) siblings of patients with type 1 diabetes; 101 controls. MAIN OUTCOME MEASURES: Analysis of progression to diabetes and expression of anti-islet autoantibodies. RESULTS: Monozygotic twin siblings had a higher risk of progression to diabetes (12/53) than dizygotic twin siblings (0/30; P<0.005). At the last follow up 22 (41.5%) monozygotic twin siblings expressed autoantibodies compared with 6 (20%) dizygotic twin siblings (P<0.05), 16 (10.7%) non-twin siblings (P<0.0001), and 6 (5.9%) controls (P<0.0001). Monozygotic twin siblings expressed multiple (>/=2) antibodies more often than dizygotic twin siblings (10/38 v 1/23; P<0.05). By life table analysis the probability of developing positive autoantibodies was higher among the monozygotic twin siblings bearing the diabetes associated HLA DQ8/DQ2 genotype than in those without this genotype (64.2% (95% confidence interval 32.5% to 96%) v 23.5% (7% to 40%) at 10 years of discordance; P<0.05). CONCLUSION: Monozygotic and dizygotic twins differ in progression to diabetes and expression of islet cell autoantibodies. Dizygotic twin siblings are similar to non-twin siblings. These two observations suggest that genetic factors play an important part in determination of islet cell autoimmunity, thus rejecting the hypothesis. In addition, there is a high penetrance of islet cell autoimmunity in DQ8/DQ2 monozygotic twin siblings.  (+info)

Diagnosis of twin reversed arterial perfusion sequence in the first trimester by transvaginal color Doppler ultrasound. (5/1447)

A case of twin reversed arterial perfusion (TRAP) sequence was diagnosed at 12 weeks' gestation using transvaginal color Doppler ultrasound, which demonstrated the presence of retrograde perfusion in the umbilical artery of the abnormal twin. Ultrasound imaging showed a monochorionic-diamniotic twin pregnancy with an inappropriately grown second twin, the morphological evaluation of which revealed an abnormal cephalic pole with acrania, diffuse subcutaneous edema and the presence of cardiac activity in an abnormal heart with a single chamber.  (+info)

Breast cancer risk in monozygotic and dizygotic female twins: a 20-year population-based cohort study in Finland from 1976 to 1995. (6/1447)

This population-based study investigated the occurrence of breast cancer over a 20-year period in a cohort of monozygotic (MZ) and dizygotic (DZ) twins in Finland. Altogether, 13,176 female twins of known zygosity who were living in Finland at the end of 1975 were identified from the Finnish Twin Cohort Study and followed-up for cancer through the Finnish Cancer Registry for the years 1976-1995. Standardized incidence ratios (SIRs) were calculated, based on national cancer incidence rates. The relative risk of breast cancer for MZ twins compared to DZ twins was decreased [SIR(MZ)/SIR(DZ) ratio = 0.78; 95% confidence interval (CI), 0.58-1.0]; the decreased risk for MZ twins (SIR = 0.76; 95% CI, 0.58-1.0) accounted for this result, whereas the risk for DZ twins did not differ from the general population risk (SIR = 0.98; 95% CI, 0.84-1.1). There was no risk decrease among MZ twins in other cancers related to reproductive behavior; i.e., number of children and age at first birth seem not to explain the decreased risk of breast cancer. Our results, which are in line with earlier studies on the same topic, suggest that prenatal influences or postnatal behavioral factors may protect MZ female twins from breast cancer.  (+info)

How identical would cloned children be? An understanding essential to the ethical debate. (7/1447)

The ban on human cloning in many countries worldwide is founded on an assumption that cloned children will be identical to each other and to their nuclear donor. This paper explores the scientific basis for this assumption, considering both the principles and practice of cloning in animals and comparing genetic and epigenetic variation in potential human clones with that in monozygotic twins.  (+info)

A spare or an individual? Cloning and the implications of monozygotic twinning. (8/1447)

The creation of Dolly, the cloned sheep, raises the scenario of cloning in humans. Neither the case for, nor against, the ethics of cloning in humans is discussed in this paper. Instead, it considers the neglected issue of the likely happiness or otherwise of the resulting children if they are born as monozygotic twins or triplets. The advantages and disadvantages of twinship are discussed in detail, and it is concluded that recognized medical risks, and incompletely understood psychological effects, should be given serious consideration.  (+info)

Monozygotic twins, also known as identical twins, are derived from a single fertilized egg (ovum) that splits and develops into two separate embryos. This results in the formation of genetically identical individuals who share the same genetic material, with the exception of potential mutations that may occur after the split. Monozygotic twins have the same sex, blood type, and other genetic traits. They are a unique pair of siblings, sharing an extraordinary degree of resemblance in physical characteristics, abilities, and behaviors.

'Diseases in Twins' is a field of study that focuses on the similarities and differences in the occurrence, development, and outcomes of diseases among twins. This research can provide valuable insights into the genetic and environmental factors that contribute to various medical conditions.

Twins can be classified into two types: monozygotic (identical) and dizygotic (fraternal). Monozygotic twins share 100% of their genes, while dizygotic twins share about 50%, similar to non-twin siblings. By comparing the concordance rates (the likelihood of both twins having the same disease) between monozygotic and dizygotic twins, researchers can estimate the heritability of a particular disease.

Studying diseases in twins also helps understand the role of environmental factors. When both twins develop the same disease, but they are discordant for certain risk factors (e.g., one twin smokes and the other does not), it suggests that the disease may have a stronger genetic component. On the other hand, when both twins share similar risk factors and develop the disease, it implies that environmental factors play a significant role.

Diseases in Twins research has contributed to our understanding of various medical conditions, including infectious diseases, cancer, mental health disorders, and developmental disorders. This knowledge can lead to better prevention strategies, early detection methods, and more targeted treatments for these diseases.

In the field of medicine, twins are defined as two offspring produced by the same pregnancy. They can be either monozygotic (identical) or dizygotic (fraternal). Monozygotic twins develop from a single fertilized egg that splits into two separate embryos, resulting in individuals who share identical genetic material. Dizygotic twins, on the other hand, result from the fertilization of two separate eggs by two different sperm cells, leading to siblings who share about 50% of their genetic material, similar to non-twin siblings.

Dizygotic twins, also known as fraternal twins, are a result of two separate sperm fertilizing two separate eggs during conception. These twins share about 50% of their genes, similar to any non-twin siblings. They may be of the same sex or different sexes and can vary in appearance, personality, and interests. Dizygotic twins typically do not share a placenta or a sac in the womb, but they may share a chorion (outer fetal membrane).

Monozygotic twinning, also known as identical twinning, is a type of twin pregnancy that occurs when a single fertilized egg (ovum) splits into two embryos during the early stages of development. This results in the formation of two genetically identical individuals who share the same set of DNA and are therefore considered to be genetic clones of each other.

Monozygotic twinning is thought to occur in about 1 in every 250 pregnancies, making it less common than dizygotic (fraternal) twinning, which occurs when two separate eggs are fertilized by two different sperm. In monozygotic twinning, the timing of the split determines the type of placenta and amniotic sac each twin will have.

If the split occurs within the first few days after fertilization, the twins will typically develop in separate amniotic sacs and have their own individual placentas. If the split occurs later, the twins may share an amniotic sac (monoamniotic) or a placenta (monochorionic), or both (monochorionic-monoamniotic).

Monozygotic twinning is associated with some increased risks for pregnancy complications, such as preterm labor and delivery, low birth weight, and twin-to-twin transfusion syndrome, a rare condition in which blood flows unevenly between the twins through shared placental blood vessels. However, most monozygotic twins are born healthy and develop normally.

Conjoined twins, also known as Siamese twins, are a rare type of monozygotic (identical) twins who are born physically connected to each other. They develop from a single fertilized egg that fails to fully separate, resulting in various degrees of fusion between their bodies. The point of connection and the extent of sharing body parts can vary greatly between sets of conjoined twins. Some may be connected at the chest, abdomen, or hips, while others may share vital organs such as the heart or brain. Treatment options depend on the type of conjunction and whether separation is possible without causing harm to either twin. Conjoined twins occur in about 1 in every 200,000 live births.

"Twin studies" is a type of research design used in medical and scientific research, particularly in the field of genetics. This method involves comparing similarities and differences between monozygotic (identical) twins and dizygotic (fraternal) twins to estimate the heritability of certain traits or conditions.

Monozygotic twins share 100% of their genetic material, while dizygotic twins share only about 50%, similar to non-twin siblings. By comparing the concordance rates (the likelihood that both twins in a pair will have the same trait or condition) between monozygotic and dizygotic twins, researchers can estimate the proportion of variation in a trait that is due to genetic factors (heritability).

Twin studies can provide valuable insights into the genetic and environmental contributions to various traits and conditions, including physical characteristics, cognitive abilities, personality traits, and susceptibility to diseases. However, it's important to note that twin studies have limitations, such as the potential for environmental influences to be confounded with genetic factors, and the assumption that monozygotic twins share all of their genetic material, which is not always the case due to rare genetic events like mutations during development.

In medical terms, triplets are a type of multiple pregnancy, where three offsprings (fetuses) develop simultaneously in the uterus of a single pregnant woman. This occurs when a woman releases more than one egg during ovulation, and all three eggs get fertilized by separate sperm cells. Triplets can also occur through the use of assisted reproductive technologies such as in vitro fertilization (IVF) where multiple embryos are transferred into the uterus.

Triplet pregnancies carry a higher risk of complications for both the mother and the offsprings compared to singleton or twin pregnancies, including preterm labor, low birth weight, and developmental issues. As such, they often require close monitoring and specialized care throughout the pregnancy.

Twin pregnancy refers to a type of multiple pregnancy where a woman is carrying two fetuses simultaneously. There are two types of twin pregnancies: monozygotic (identical) and dizygotic (fraternal). Monoygotic twins occur when a single fertilized egg (zygote) splits and develops into two separate embryos, resulting in identical twins who share the same genetic material. Dizygotic twins, on the other hand, result from the fertilization of two separate eggs by two different sperm cells, leading to non-identical twins who have their own unique genetic material.

Twin pregnancies are associated with higher risks of complications compared to singleton pregnancies, including preterm labor, low birth weight, gestational diabetes, and preeclampsia. Close monitoring by healthcare providers is essential to ensure the best possible outcomes for both the mother and the twins.

Dermatoglyphics is the study of the fingerprints, palm prints, and other skin ridge patterns found on the hands and feet. These patterns are formed during fetal development and are generally considered to be unique to each individual. Dermatoglyphics can provide important clues about a person's genetic makeup and health status, and they are often used in forensic investigations to help identify individuals. In medicine, dermatoglyphics may be used to help diagnose certain genetic disorders or birth defects.

Multiple pregnancy is a type of gestation where more than one fetus is carried simultaneously in the uterus. The most common forms of multiple pregnancies are twins (two fetuses), triplets (three fetuses), and quadruplets (four fetuses). Multiple pregnancies can occur when a single fertilized egg splits into two or more embryos (monozygotic) or when more than one egg is released and gets fertilized during ovulation (dizygotic). The risk of multiple pregnancies increases with the use of assisted reproductive technologies, such as in vitro fertilization. Multiple pregnancies are associated with higher risks for both the mother and the fetuses, including preterm labor, low birth weight, and other complications.

The term "environment" in a medical context generally refers to the external conditions and surroundings that can have an impact on living organisms, including humans. This includes both physical factors such as air quality, water supply, soil composition, temperature, and radiation, as well as biological factors such as the presence of microorganisms, plants, and animals.

In public health and epidemiology, the term "environmental exposure" is often used to describe the contact between an individual and a potentially harmful environmental agent, such as air pollution or contaminated water. These exposures can have significant impacts on human health, contributing to a range of diseases and disorders, including respiratory illnesses, cancer, neurological disorders, and reproductive problems.

Efforts to protect and improve the environment are therefore critical for promoting human health and preventing disease. This includes measures to reduce pollution, conserve natural resources, promote sustainable development, and mitigate the impacts of climate change.

Quadruplets are defined in medicine as a type of multiple birth where four offspring are produced from the same pregnancy. This occurs when a single fertilized egg divides into four embryos, or more rarely, when four separate eggs are each fertilized by different sperm. Quadruplets face higher risks of preterm birth and other complications compared to singleton pregnancies.

Pregnancy is a physiological state or condition where a fertilized egg (zygote) successfully implants and grows in the uterus of a woman, leading to the development of an embryo and finally a fetus. This process typically spans approximately 40 weeks, divided into three trimesters, and culminates in childbirth. Throughout this period, numerous hormonal and physical changes occur to support the growing offspring, including uterine enlargement, breast development, and various maternal adaptations to ensure the fetus's optimal growth and well-being.

Quintuplets are defined in medical terms as a rare type of multiple pregnancy where a woman gives birth to five offspring at once. This occurs when one fertilized egg divides into five embryos, a phenomenon known as monozygotic quintuplets. Each baby shares the same genetic material and may be of the same sex. Quintuplets have a higher risk of preterm birth and other complications compared to singleton pregnancies. The survival rate for quintuplets has improved significantly over time due to advancements in medical technology and neonatal care.

Fetofetal transfusion is a medical condition that can occur in pregnancies with multiple fetuses, such as twins or higher-order multiples. It refers to the transfer of blood from one fetus (donor) to another (recipient) through anastomotic connections in their shared placenta.

In some cases, these anastomoses can result in an imbalance in blood flow between the fetuses, leading to a net transfer of blood from one fetus to the other. This situation is more likely to occur when there is a significant weight or size difference between the fetuses, known as twin-to-twin transfusion syndrome (TTTS).

In TTTS, the recipient fetus receives an excess of blood, which can lead to high-output cardiac failure, hydrops, and potential intrauterine demise. Meanwhile, the donor fetus may become anemic, growth-restricted, and at risk for hypovolemia and intrauterine demise as well. Fetofetal transfusion can be diagnosed through ultrasound evaluation and managed with various interventions, including laser ablation of anastomotic vessels or fetoscopic surgery, depending on the severity and gestational age at diagnosis.

A phenotype is the physical or biochemical expression of an organism's genes, or the observable traits and characteristics resulting from the interaction of its genetic constitution (genotype) with environmental factors. These characteristics can include appearance, development, behavior, and resistance to disease, among others. Phenotypes can vary widely, even among individuals with identical genotypes, due to differences in environmental influences, gene expression, and genetic interactions.

Pregnancy reduction, multifetal refers to the medical procedure used to decrease the number of fetuses in a multiple pregnancy, such as twins or higher-order multiples (triplets, quadruplets, etc.). This is also known as selective reduction or selective termination. The goal of this procedure is to reduce the risk of complications associated with multifetal pregnancies, including preterm labor, low birth weight, and pregnancy loss.

The procedure typically involves an ultrasound-guided injection of a medication that stops the development of one or more fetuses. This is usually performed during the first trimester of pregnancy. The decision to undergo pregnancy reduction is often based on a variety of factors, including maternal age, medical history, and personal preferences. It's important to note that this procedure carries its own risks, such as infection, bleeding, and loss of the remaining fetuses, so it should be carefully considered and discussed with healthcare providers.

Genetic predisposition to disease refers to an increased susceptibility or vulnerability to develop a particular illness or condition due to inheriting specific genetic variations or mutations from one's parents. These genetic factors can make it more likely for an individual to develop a certain disease, but it does not guarantee that the person will definitely get the disease. Environmental factors, lifestyle choices, and interactions between genes also play crucial roles in determining if a genetically predisposed person will actually develop the disease. It is essential to understand that having a genetic predisposition only implies a higher risk, not an inevitable outcome.

Gene-Environment Interaction (GEI) is a concept in genetics that refers to the way in which genetic variations and environmental factors interact to influence traits or disease susceptibility. It describes a situation where the effect of an environmental exposure on a particular trait or disease outcome is dependent on the genetic makeup of the individual, and vice versa.

In other words, GEI suggests that the impact of environmental factors on health outcomes may be different depending on a person's genetic background, and similarly, the influence of certain genes on health outcomes may depend on the presence or absence of specific environmental exposures. This interaction can help explain why some individuals are more susceptible to certain diseases or traits than others, even when exposed to similar environments.

GEI is an important concept in precision medicine, as understanding these interactions can help identify individuals who are at higher risk for certain diseases and develop targeted prevention and treatment strategies based on their genetic and environmental profiles.

A newborn infant is a baby who is within the first 28 days of life. This period is also referred to as the neonatal period. Newborns require specialized care and attention due to their immature bodily systems and increased vulnerability to various health issues. They are closely monitored for signs of well-being, growth, and development during this critical time.

A registry in the context of medicine is a collection or database of standardized information about individuals who share a certain condition or attribute, such as a disease, treatment, exposure, or demographic group. These registries are used for various purposes, including:

* Monitoring and tracking the natural history of diseases and conditions
* Evaluating the safety and effectiveness of medical treatments and interventions
* Conducting research and generating hypotheses for further study
* Providing information to patients, clinicians, and researchers
* Informing public health policy and decision-making

Registries can be established for a wide range of purposes, including disease-specific registries (such as cancer or diabetes registries), procedure-specific registries (such as joint replacement or cardiac surgery registries), and population-based registries (such as birth defects or cancer registries). Data collected in registries may include demographic information, clinical data, laboratory results, treatment details, and outcomes.

Registries can be maintained by a variety of organizations, including hospitals, clinics, academic medical centers, professional societies, government agencies, and industry. Participation in registries is often voluntary, although some registries may require informed consent from participants. Data collected in registries are typically de-identified to protect the privacy of individuals.

Inheritance patterns refer to the way in which a particular genetic trait or disorder is passed down from one generation to the next, following the rules of Mendelian genetics. There are several different inheritance patterns, including:

1. Autosomal dominant: A single copy of the altered gene in each cell is sufficient to cause the disorder. An affected parent has a 50% chance of passing on the altered gene to each offspring.
2. Autosomal recessive: Two copies of the altered gene in each cell are necessary for the disorder to occur. Both parents must be carriers of the altered gene and have a 25% chance of passing on the altered gene to each offspring, who may then develop the disorder.
3. X-linked dominant: The altered gene is located on the X chromosome, and one copy of the altered gene in each cell is sufficient to cause the disorder. Females are more likely to be affected than males, and an affected female has a 50% chance of passing on the altered gene to each offspring.
4. X-linked recessive: The altered gene is located on the X chromosome, and two copies of the altered gene in each cell are necessary for the disorder to occur. Males are more likely to be affected than females, and an affected male will pass on the altered gene to all of his daughters (who will be carriers) but none of his sons.
5. Mitochondrial inheritance: The altered gene is located in the mitochondria, the energy-producing structures in cells. Both males and females can pass on mitochondrial genetic disorders, but only through the female line because offspring inherit their mother's mitochondria.

Understanding inheritance patterns helps medical professionals predict the likelihood of a genetic disorder occurring in families and provides information about how a disorder may be passed down through generations.

Embryo transfer is a medical procedure that involves the transfer of an embryo, which is typically created through in vitro fertilization (IVF), into the uterus of a woman with the aim of establishing a pregnancy. The embryo may be created using the intended parent's own sperm and eggs or those from donors. After fertilization and early cell division, the resulting embryo is transferred into the uterus of the recipient mother through a thin catheter that is inserted through the cervix. This procedure is typically performed under ultrasound guidance to ensure proper placement of the embryo. Embryo transfer is a key step in assisted reproductive technology (ART) and is often used as a treatment for infertility.

Behavioral genetics is a subfield of genetics that focuses on the study of the genetic basis of behavior. It seeks to understand how genes and environment interact to influence individual differences in behaviors such as personality traits, cognitive abilities, psychiatric disorders, and addiction. This field integrates knowledge from genetics, psychology, neuroscience, and statistics to investigate the complex relationship between genetic factors and behavioral outcomes. Research in behavioral genetics includes studies of twins, families, and adopted individuals, as well as animal models, to identify specific genes or genetic variations that contribute to the heritability of various behaviors. Understanding these genetic influences can provide insights into the prevention, diagnosis, and treatment of behavioral disorders.

Heredity, in medical terms, refers to the passing on of genetic characteristics from parents to their offspring through the transmission of genes. These genes carry the information that determines many traits, such as eye color, hair color, height, and certain health conditions. Heredity plays a significant role in understanding the causes of various diseases and disorders, as some are strongly influenced by genetic factors. However, it's important to note that environmental factors can also interact with genetic predispositions to influence the expression of these traits.

Birth weight refers to the first weight of a newborn infant, usually taken immediately after birth. It is a critical vital sign that indicates the baby's health status and is used as a predictor for various short-term and long-term health outcomes.

Typically, a full-term newborn's weight ranges from 5.5 to 8.8 pounds (2.5 to 4 kg), although normal birth weights can vary significantly based on factors such as gestational age, genetics, maternal health, and nutrition. Low birth weight is defined as less than 5.5 pounds (2.5 kg), while high birth weight is greater than 8.8 pounds (4 kg).

Low birth weight babies are at a higher risk for various medical complications, including respiratory distress syndrome, jaundice, infections, and developmental delays. High birth weight babies may face challenges with delivery, increased risk of obesity, and potential metabolic issues later in life. Regular prenatal care is essential to monitor fetal growth and ensure a healthy pregnancy and optimal birth weight for the baby.

Mosaicism, in the context of genetics and medicine, refers to the presence of two or more cell lines with different genetic compositions in an individual who has developed from a single fertilized egg. This means that some cells have one genetic makeup, while others have a different genetic makeup. This condition can occur due to various reasons such as errors during cell division after fertilization.

Mosaicism can involve chromosomes (where whole or parts of chromosomes are present in some cells but not in others) or it can involve single genes (where a particular gene is present in one form in some cells and a different form in others). The symptoms and severity of mosaicism can vary widely, depending on the type and location of the genetic difference and the proportion of cells that are affected. Some individuals with mosaicism may not experience any noticeable effects, while others may have significant health problems.

A "social environment" is not a term that has a specific medical definition, but it is often used in the context of public health and social sciences to refer to the physical and social conditions, relationships, and organized institutions that influence the health and well-being of individuals and communities.

The social environment includes factors such as:

* Social support networks (family, friends, community)
* Cultural norms and values
* Socioeconomic status (income, education, occupation)
* Housing and neighborhood conditions
* Access to resources (food, healthcare, transportation)
* Exposure to discrimination, violence, and other stressors

These factors can have a significant impact on health outcomes, as they can influence behaviors related to health (such as diet, exercise, and substance use), as well as exposure to disease and access to healthcare. Understanding the social environment is essential for developing effective public health interventions and policies that promote health equity and reduce health disparities.

I'm not sure I understand your question. "Denmark" is a country located in Northern Europe, and it is not a medical term or concept. It is the southernmost of the Nordic countries, and it consists of the Jutland peninsula and several islands in the Baltic Sea. The capital city of Denmark is Copenhagen.

If you are looking for information about a medical condition that may be associated with Denmark, could you please provide more context or clarify your question? I would be happy to help you with more specific information if I can.

Genetic models are theoretical frameworks used in genetics to describe and explain the inheritance patterns and genetic architecture of traits, diseases, or phenomena. These models are based on mathematical equations and statistical methods that incorporate information about gene frequencies, modes of inheritance, and the effects of environmental factors. They can be used to predict the probability of certain genetic outcomes, to understand the genetic basis of complex traits, and to inform medical management and treatment decisions.

There are several types of genetic models, including:

1. Mendelian models: These models describe the inheritance patterns of simple genetic traits that follow Mendel's laws of segregation and independent assortment. Examples include autosomal dominant, autosomal recessive, and X-linked inheritance.
2. Complex trait models: These models describe the inheritance patterns of complex traits that are influenced by multiple genes and environmental factors. Examples include heart disease, diabetes, and cancer.
3. Population genetics models: These models describe the distribution and frequency of genetic variants within populations over time. They can be used to study evolutionary processes, such as natural selection and genetic drift.
4. Quantitative genetics models: These models describe the relationship between genetic variation and phenotypic variation in continuous traits, such as height or IQ. They can be used to estimate heritability and to identify quantitative trait loci (QTLs) that contribute to trait variation.
5. Statistical genetics models: These models use statistical methods to analyze genetic data and infer the presence of genetic associations or linkage. They can be used to identify genetic risk factors for diseases or traits.

Overall, genetic models are essential tools in genetics research and medical genetics, as they allow researchers to make predictions about genetic outcomes, test hypotheses about the genetic basis of traits and diseases, and develop strategies for prevention, diagnosis, and treatment.

'Abnormalities, Multiple' is a broad term that refers to the presence of two or more structural or functional anomalies in an individual. These abnormalities can be present at birth (congenital) or can develop later in life (acquired). They can affect various organs and systems of the body and can vary greatly in severity and impact on a person's health and well-being.

Multiple abnormalities can occur due to genetic factors, environmental influences, or a combination of both. Chromosomal abnormalities, gene mutations, exposure to teratogens (substances that cause birth defects), and maternal infections during pregnancy are some of the common causes of multiple congenital abnormalities.

Examples of multiple congenital abnormalities include Down syndrome, Turner syndrome, and VATER/VACTERL association. Acquired multiple abnormalities can result from conditions such as trauma, infection, degenerative diseases, or cancer.

The medical evaluation and management of individuals with multiple abnormalities depend on the specific abnormalities present and their impact on the individual's health and functioning. A multidisciplinary team of healthcare professionals is often involved in the care of these individuals to address their complex needs.

Turner Syndrome is a genetic disorder that affects females, caused by complete or partial absence of one X chromosome. The typical karyotype is 45,X0 instead of the normal 46,XX in women. This condition leads to distinctive physical features and medical issues in growth, development, and fertility. Characteristic features include short stature, webbed neck, low-set ears, and swelling of the hands and feet. Other potential symptoms can include heart defects, hearing and vision problems, skeletal abnormalities, kidney issues, and learning disabilities. Not all individuals with Turner Syndrome will have every symptom, but most will require medical interventions and monitoring throughout their lives to address various health concerns associated with the condition.

Micromanipulation is a term used in the field of medicine, specifically in assisted reproductive technologies (ARTs) such as in vitro fertilization (IVF). It refers to a technique that involves the manipulation of oocytes (human eggs), sperm, and/or embryos under a microscope using micromanipulative tools and equipment.

The most common form of micromanipulation is intracytoplasmic sperm injection (ICSI), where a single sperm is selected and injected directly into the cytoplasm of an oocyte to facilitate fertilization. Other forms of micromanipulation include assisted hatching (AH), where a small opening is made in the zona pellucida (the protective layer surrounding the embryo) to help the embryo hatch and implant into the uterus, and embryo biopsy, which involves removing one or more cells from an embryo for genetic testing.

Micromanipulation requires specialized training and equipment and is typically performed in IVF laboratories by experienced embryologists. The goal of micromanipulation is to improve the chances of successful fertilization, implantation, and pregnancy, particularly in cases where conventional methods have been unsuccessful or when there are specific fertility issues, such as male factor infertility or genetic disorders.

The chorion is the outermost fetal membrane that surrounds the developing conceptus (the embryo or fetus and its supporting structures). It forms early in pregnancy as an extraembryonic structure, meaning it arises from cells that will not become part of the actual body of the developing organism. The chorion plays a crucial role in pregnancy by contributing to the formation of the placenta, which provides nutrients and oxygen to the growing embryo/fetus and removes waste products.

One of the most important functions of the chorion is to produce human chorionic gonadotropin (hCG), a hormone that signals the presence of pregnancy and maintains the corpus luteum, a temporary endocrine structure in the ovary that produces progesterone during early pregnancy. Progesterone is essential for preparing the uterus for implantation and maintaining the pregnancy.

The chorion consists of two layers: an inner cytotrophoblast layer and an outer syncytiotrophoblast layer. The cytotrophoblast layer is made up of individual cells, while the syncytiotrophoblast layer is a multinucleated mass of fused cytotrophoblast cells. These layers interact with the maternal endometrium (the lining of the uterus) to form the placenta and facilitate exchange between the mother and the developing fetus.

In summary, the chorion is a vital extraembryonic structure in pregnancy that contributes to the formation of the placenta, produces hCG, and interacts with the maternal endometrium to support fetal development.

Blood group antigens are molecular markers found on the surface of red blood cells (RBCs) and sometimes other types of cells in the body. These antigens are proteins, carbohydrates, or glycoproteins that can stimulate an immune response when foreign antigens are introduced into the body.

There are several different blood group systems, but the most well-known is the ABO system, which includes A, B, AB, and O blood groups. The antigens in this system are called ABO antigens. Individuals with type A blood have A antigens on their RBCs, those with type B blood have B antigens, those with type AB blood have both A and B antigens, and those with type O blood have neither A nor B antigens.

Another important blood group system is the Rh system, which includes the D antigen. Individuals who have this antigen are considered Rh-positive, while those who do not have it are considered Rh-negative.

Blood group antigens can cause complications during blood transfusions and pregnancy if there is a mismatch between the donor's or fetus's antigens and the recipient's antibodies. For example, if a person with type A blood receives type B blood, their anti-B antibodies will attack the foreign B antigens on the donated RBCs, causing a potentially life-threatening transfusion reaction. Similarly, if an Rh-negative woman becomes pregnant with an Rh-positive fetus, her immune system may produce anti-D antibodies that can cross the placenta and attack the fetal RBCs, leading to hemolytic disease of the newborn.

It is important for medical professionals to determine a patient's blood group before performing a transfusion or pregnancy-related procedures to avoid these complications.

Single embryo transfer (SET) is a medical procedure that involves the transplantation of a single embryo into a woman's uterus during in vitro fertilization (IVF) treatments. The aim of SET is to reduce the risk of multiple pregnancies, which can pose significant health risks to both the mother and the babies.

In IVF, multiple eggs are typically fertilized in the laboratory, resulting in several embryos. Traditionally, multiple embryos have been transferred into the uterus to increase the chances of a successful pregnancy. However, this approach also increases the risk of multiple pregnancies, which can lead to complications such as preterm labor, low birth weight, and gestational diabetes.

With SET, only one embryo is transferred, reducing the risk of multiple pregnancies while still providing a good chance of success in appropriately selected patients. The decision to perform SET is based on several factors, including the age and health of the patient, the quality of the embryos, and previous reproductive history.

Overall, single embryo transfer is a safe and effective way to increase the chances of a healthy singleton pregnancy while minimizing the risks associated with multiple pregnancies.

I believe there might be a misunderstanding in your question. The "Vietnam Conflict" is not a medical term, but rather a historical event - it was a long, violent conflict that took place in Vietnam, Laos, and Cambodia from 1959 to 1975.

However, I can provide you with some information on how the Vietnam War may relate to medical and health-related topics:

The Vietnam Conflict had significant impacts on the physical and mental health of both military personnel and civilians involved. Some common health issues related to this conflict include:

1. Agent Orange Exposure: Many US soldiers were exposed to Agent Orange, a powerful herbicide used by the US military during the war. This exposure has been linked to various health problems, including different types of cancer, neurological disorders, and birth defects in their offspring.
2. Post-Traumatic Stress Disorder (PTSD): The Vietnam War is known for its high prevalence of PTSD among veterans. The traumatic experiences during the war led to long-term psychological issues, such as anxiety, depression, and substance abuse disorders.
3. Traumatic Brain Injury (TBI): Military personnel involved in the conflict were at risk of TBIs due to explosions and other combat-related injuries. These injuries can lead to cognitive impairments, motor function issues, and emotional disturbances.
4. Physical Disabilities: Amputations, sensory losses, and other physical disabilities were common among veterans due to landmines, gunshot wounds, and other war-related injuries.
5. Infectious Diseases: Tropical diseases, such as malaria and tuberculosis, were prevalent among both military personnel and civilians during the Vietnam Conflict. Additionally, soldiers were at risk of contracting sexually transmitted infections due to high-risk behaviors.

These are just a few examples of how the Vietnam Conflict intersects with medical and health topics.

I'm sorry for any confusion, but "Sweden" is not a medical term. It is a country located in northern Europe. If you have any questions about medical terminology or concepts, I would be happy to help answer those!

Monozygotic twins or unrelated stepchildren? On the relationship between economic psychology and behavioral economics. Journal ...
... twins become conjoined twins. Non-conjoined monozygotic twins form up to day 14 of embryonic development, but when twinning ... Monozygotic twins who share a placenta can develop twin-to-twin transfusion syndrome. This condition means that blood from one ... The children of monozygotic twins test genetically as half-siblings (or full siblings, if a pair of monozygotic twins ... Monozygotic twins can have markedly different epigenetic profiles. A study of 80 pairs of monozygotic twins ranging in age from ...
"Thanatophoric dysplasia in monozygotic twins". TheFetus.net. Archived from the original on December 12, 2008. Retrieved 2016-03 ...
An example is monozygotic twins. To have a complete picture of what is going on with the epigenetic tapestry of our cells, ... Epigenetics Editorial Board Wade, Nicholas (5 July 2005). "Explaining Differences in Twins - New York Times". The New York ...
Edwards JH, Dent T, Kahn J (June 1966). "Monozygotic twins of different sex". Journal of Medical Genetics. 3 (2): 117-123. doi: ... While no humans - not even monozygotic twins - are genetically identical, two humans on average will have a genetic similarity ... Machin GA (January 1996). "Some causes of genotypic and phenotypic discordance in monozygotic twin pairs". American Journal of ... January 2021). "Differences between germline genomes of monozygotic twins". Nature Genetics. 53 (1): 27-34. doi:10.1038/s41588- ...
Tomasz Dziedzic, Ewa Fabianska, and Zuzanna Toeplitz (2007). Handwriting of Monozygotic and Dizygotic Twins. Problems of ... Even identical twins who share appearance and genetics do not have the same handwriting. Characteristics of handwriting include ... "On the Discriminability of the Handwriting of Twins". J Forensic Sci.; 53(2):430-46. ...
In 2011, a case of monozygotic twins with divergent ROHHAD phenotypes was reported. One twin was affected with ROHHAD and ... "Monozygotic Twins Discordant for ROHHAD Phenotype". Pediatrics. 128 (3): e711-e715. doi:10.1542/peds.2011-0155. ISSN 0031-4005 ... developed symptoms, while the other twin developed normally. This report questioned the theory that ROHHAD is genetically ...
Gedda L, Sciacca A, Brenci G, Villatico S, Bonanni G, Gueli N, Talone C (1984). "Situs viscerum specularis in monozygotic twins ... Some identical twins-known as mirror image twins-can have a mirror-imaged anatomy, a congenital condition with the appendix ... "Unusual Types of Twins". Multiples of America. Archived from the original on 2 May 2014. Retrieved 30 April 2014. ...
One early case that drew attention to the syndrome was a report of monozygotic twin sisters with a ring 22, one of the first ... Lindenbaum RH, Bobrow M, Barber L (March 1973). "Monozygotic Twins with Ring Chromosome 22". Journal of Medical Genetics. 10 (1 ... recorded reports of a shared chromosomal anomaly between twins. Cat eye syndrome Emanuel syndrome Unique, Jeffries A, Hultén M ...
Monozygotic twins carry identical genomic information. Therefore, if they are discordant for a particular disease or phenotype ... Another limitation is recruiting a large enough cohort of discordant monozygotic twins with the disease of interest. ... Longitudinal studies using disease-discordant monozygotic twins gives the added benefit of ruling out genetic influences on ... including differences in disease-associated epigenetic marks between monozygotic twins, the rising incidence of type 1 diabetes ...
Critics of twin studies argue that they are based on false or questionable assumptions, including that monozygotic twins share ... Maudsley Bipolar Twin Study Minnesota Twin Family Study Twins Early Development Study NASA Twins Study The power of twin ... The classical twin design compares the similarity of monozygotic (identical) and dizygotic (fraternal) twins. If identical ... Not really identical: epigenetic differences in monozygotic twins and implications for twin studies in psychiatry. Haque FN, ...
Monoamniotic twins are always monozygotic (identical twins). Monochorionic-Diamniotic twins are almost always monozygotic, with ... Monochorionic twins are monozygotic (identical) twins that share the same placenta. If the placenta is shared by more than two ... Monochorionic twins occur in 0.3% of all pregnancies. Seventy-five percent of monozygotic twin pregnancies are monochorionic; ... If one twin dies in utero, blood accumulates in that twin's body, causing exsanguination of the remaining twin. In the case of ...
1984). "Situs viscerum specularis in monozygotic twins". Acta Genet Med Gemellol (Roma). 33 (1): 81-5. doi:10.1017/ ... twins. About 25% of individuals with situs inversus have an underlying condition known as primary ciliary dyskinesia (PCD). PCD ...
... however the monozygotic twins case studies indicate there is an epigenetic component. Synesthesia might also be an oligogenic ... a case study of discordant monozygotic twins". Neurocase. 8 (4): 338-342. doi:10.1076/neur.8.3.338.16194. PMID 12221147. S2CID ... a case study of discordant monozygotic twins". Neurocase. 8 (4): 338-342. doi:10.1076/neur.8.3.338.16194. PMID 12221147. S2CID ... twins While both twins had the same genome with the potential for phenotypic expression of synesthesia, only one had documented ...
... monozygotic twins born to normal and non consanguineous parents, presenting with an unusual facial appearance, cortical atrophy ... "Smith-Fineman-Myers syndrome in apparently monozygotic twins". American Journal of Medical Genetics. 79 (3): 205-8. doi:10.1002 ...
2000) reported a pair of monozygotic twins with Fryns syndrome discordant for severity of diaphragmatic defect. Both twins had ... Vargas JE, Cox GF, Korf BR (September 2000). "Discordant phenotype in monozygotic twins with Fryns syndrome". Am. J. Med. Genet ... Twin A lacked an apparent diaphragmatic defect, and at 1 year of age had mild developmental delay. Twin B had a left congenital ...
A case study of discordant monozygotic twins. Neurocase, 8, 338-342. Cheesman, J., & Merikle, P. M. (1986). Distinguishing ...
A more recent study, where 114 monozygotic twins and 80 dizygotic twins were analyzed for the DNA methylation status of around ... epigenetic differences in monozygotic twins and implications for twin studies in psychiatry". American Journal of Medical ... Dizygotic (fraternal) and monozygotic (identical) twins show evidence of epigenetic influence in humans. DNA sequence ... July 2005). "Epigenetic differences arise during the lifetime of monozygotic twins". Proceedings of the National Academy of ...
The classic twin study compares monozygotic and dizygotic twins. If the monozygotic twins resemble each other much more closely ... Monozygotic, or identical, twins share 100% of their genes, while dizygotic, or fraternal, twins share on average 50% of their ... Early twin studies were replicated later using twins with OCD meeting DSM criteria and ascertainment of probands, but only a ... Twin Research and Human Genetics. 8 (5): 450-458. doi:10.1375/twin.8.5.450. Pauls, David L. (2010). "The Genetics of Obsessive- ...
... monozygotic twins usually have exactly identical genomes. Scientists have focused on comparison studies of such twins for ... Bell, Jordana T.; Spector, Tim D. (1 March 2011). "A twin approach to unraveling epigenetics". Trends in Genetics. 27 (3): 116- ... evaluating the heritability of genes and the roles of epigenetics in divergences and similarities between monozygotic twins, ... Petronis, Arturas (1 July 2006). "Epigenetics and twins: three variations on the theme". Trends in Genetics. 22 (7): 347-350. ...
Chen H, Huang H, Chang T, Lai C, Soong Y (2006). "Pure XY gonadal dysgenesis and agenesis in monozygotic twins". Fertility and ...
An extreme case of this was seen where monozygotic female twins had extreme variance in expression of Menkes disease (an X- ... "Menkes disease with discordant phenotype in female monozygotic twins". American Journal of Medical Genetics. Part A. 167A (11 ... linked disorder) resulting in the death of one twin while the other remained asymptomatic. It is thought that X-inactivation ...
Mono-zygotic twin studies reveal 8-29% of changes between the twins' teeth is from the environment. Several studies of mono- ... Epigenetic markers differ the most in monozygotic twins who spend time apart or have a very different medical history. As twins ... Monozygotic twins provide information on epigenetic differences that are not from genetic factors. ... The rate of disease discordance between monozygotic twins is usually over 50%, including heritable diseases. This does not ...
A Japanese case study of monozygotic twins discordant for schizophrenia (one has the diagnosis while the other does not) draws ... Twin studies have shown that an identical twin has ~50% risk of also developing the disorder. Family studies indicate that the ... The average concordance rates are higher for identical twins than for fraternal twins and evidence also suggests that the ... A case report of monozygotic twins". Psychiatry and Clinical Neurosciences. 57 (3): 271-274. doi:10.1046/j.1440-1819.2003.01116 ...
Two monozygotic female twins had the same IRF6 mutation; however Twin A was born with a bilateral cleft lip, whereas Twin B had ... Both twins were diagnosed with VWS. The twins' father had lip pits alone and a family history of CLP, CP, CL, and/or lip pits. ... 1], OMIM Van der Woude Syndrome 2 Jobling R, Ferrier RA, McLeod R, Petrin AL, Murray JC, Thomas MA (2011). "Monozygotic twins ... This study is not the first case of different phenotypes occurring between monozygotic twins. Possible causes of phenotypic ...
"Ancient DNA reveals monozygotic newborn twins from the Upper Palaeolithic". Communications Biology. 3 (1): 650. doi:10.1038/ ... 2020) examined the remains of one adult male and two twin boys from a Gravettian site in Austria. All belonged to haplogroup Y- ...
... are identified as the earliest known case of monozygotic twins by Teschler-Nicola et al. (2020). A study on the genome of a ~ ... "Ancient DNA reveals monozygotic newborn twins from the Upper Palaeolithic". Communications Biology. 3 (1): Article number 650. ...
"Ancient DNA reveals monozygotic newborn twins from the Upper Palaeolithic". Communications Biology. 3 (1): 650. doi:10.1038/ ... At the same site, two twin boys were also found, both were assigned to haplogroup I*. Haplogroup IJ was in the Middle East and/ ...
... among monozygotic twins and a 30% one among dizygotic twins. In 2000, Bailey, Dunne and Martin studied a larger sample of 4,901 ... MZ' indicates identical twins with the same sets of genes and 'DZ' indicates fraternal twins where genes are mixed to an extent ... A 2008 study of all adult twins in Sweden (more than 7,600 twins) found that same-sex behaviour was explained by both heritable ... They found 20% concordance in the male identical or MZ twins and 24% concordance for the female identical or MZ twins. Self ...
Sep 1998). "Identical de novo mutation at the D4F104S1 locus in monozygotic male twins affected by facioscapulohumeral muscular ... "Extreme variability of expression in monozygotic twins with FSH muscular dystrophy". Neurology. 43 (2): 345-8. doi:10.1212/wnl. ... Distribution and degree of muscle weakness is extremely variable, even between identical twins. Musculoskeletal pain is very ...
A pair of monozygotic male twins discordant for ectopia vesicae urinariae is described. There is no reason to think that any ...
Monozygotic twin girls are reported, one of whom has the typical clinical features of Duchenne muscular dystrophy despite a ... This segregation was followed by, and may even have resulted in, twinning into a female pair, one normal and one with the full ... in 16 independent somatic cell hybrids made between cells derived from each girl and a mouse line suggest that in one twin only ...
Ovarian transplantation between monozygotic twins discordant for premature ovarian failure. N Engl J Med 2005; 53:58-63. ... A series of monozygotic twins discordant for ovarian failure: ovary transplantation (cortical versus microvascular) and ... Ovarian transplantation in a series of monozygotic twins discordant for ovarian failure. N Engl J Med2007;356:1382-1384. ... Discordant KCNQ1OT1 imprinting in sets of monozygotic twins discordant for Beckwith-Wiedemann syndrome. Hum Mol Genet 2002;11: ...
We performed an intrapair comparison in 27 monozygotic twin pairs, one of whom was taking third-generation OC, whereas the ... Markers for cardiovascular disease in monozygotic twins discordant for the use of third-generation oral contraceptives. In: ... We performed an intrapair comparison in 27 monozygotic twin pairs, one of whom was taking third-generation OC, whereas the ... We performed an intrapair comparison in 27 monozygotic twin pairs, one of whom was taking third-generation OC, whereas the ...
Historic Embryology - Twinning 1915 Twin embryos 17-19 somites , 1916 Conjoined Twins , 1922 Monozygotic origin identical twins ... Arey LB. Direct proof of the monozygotic origin of human identical twins. (1922) Anat. Rec. : 245- . ... Mammalian monozygotic twins do not arise by the separation of early blastomeres, as too often has been assumed; on the contrary ... This historic 1922 paper by Arey describes development of monozygotic twins. See the comment on this paper by Frederic Lewis. ...
... and beliefs in socialization of monozygotic twins. Psicol. rev. (Belo Horizonte) [online]. 2010, vol.16, n.3, pp. 575-593. ISSN ... Keywords : twins; beliefs; culture; socialization; childhood development. · abstract in Portuguese , Spanish · text in ... The cultural psychology approach demands a qualitative, systemic analysis of complexities of twin development, considering the ... illustrated by the analysis of an episode between a pair of male twin children and their grandpa. We integrated these data with ...
What does it mean to exist in a superposition of states? Does quantum fuzziness spill over to our macroscopic domain? Is experienced reality inherently probabilistic or does the universe split in two every time we make a choice? An experimental study.
Erratum: Heriability of the P300 components of the event-related potential: A study of monozygotic and dizygotic twins ( ... title = "Erratum: Heriability of the P300 components of the event-related potential: A study of monozygotic and dizygotic twins ... Erratum: Heriability of the P300 components of the event-related potential: A study of monozygotic and dizygotic twins ( ... Erratum: Heriability of the P300 components of the event-related potential: A study of monozygotic and dizygotic twins ( ...
Handwriting of Monozygotic and Dizygotic Twins NCJ Number. 226840. Journal. Problems of Forensic Sciences ...
Immunologically restricted and inhibitory anti-Ro/SSA in monozygotic twins. Lupus. 1997; 6(4):395-8. ...
The co-twin control design was used to explore these mental health issues in MZ twins concordant and discordant for a motor ... The co-twin control design was used to explore these mental health issues in MZ twins concordant and discordant for a motor ... The co-twin control design was used to explore these mental health issues in MZ twins concordant and discordant for a motor ... The co-twin control design was used to explore these mental health issues in MZ twins concordant and discordant for a motor ...
To analyze genetic differences between 2 pairs of monozygotic twins that had discordant aortic valve morphology, with 1 twin in ... To analyze genetic differences between 2 pairs of monozygotic twins that had discordant aortic valve morphology, with 1 twin in ... To analyze genetic differences between 2 pairs of monozygotic twins that had discordant aortic valve morphology, with 1 twin in ... To analyze genetic differences between 2 pairs of monozygotic twins that had discordant aortic valve morphology, with 1 twin in ...
Monozygotic twins or unrelated stepchildren? On the relationship between economic psychology and behavioral economics. Journal ...
Twins, Dizygotic * Twins, Monozygotic Grants and funding * WT_/Wellcome Trust/United Kingdom ... Here, we compared microbiotas across ,1,000 fecal samples obtained from the TwinsUK population, including 416 twin pairs. We ... 3 Department of Twin Research and Genetic Epidemiology, Kings College London, London SE1 7EH, UK. ...
13 monozygotic twin pairs concordant for schizophrenia, and several normal monozygotic twin samples. Results: The a-b ridge ... Method: Four dermatoglyphic markers of prenatal growth were obtained by established procedures from 26 monozygotic twin pairs ... In comparison with their well co-twins, the affected twins, in discordant pairs, had developed fewer epidermal ridges in the a- ... In contrast, no significant differences were found between the affected twins and their well co-twins on markers associated ...
Sexual discordance in monozygotic twins. Perlman EJ, Stetten G, Tuck-Müller CM, Farber RA, Neuman WL, Blakemore KJ, Hutchins GM ...
The effect of intra-uterine growth on Verbal IQ scores in childhood: a monozygotic twin study. Pediatrics. 126 (5), pp. e1095- ... 2010) The effect of intra-uterine growth on Verbal IQ scores in childhood: a monozygotic twin study Pediatrics 126 (5) pp. ... The effect of intra-uterine growth on Verbal IQ scores in childhood: a monozygotic twin study. Article ... The results suggest that the mean advantage for heavier twins relative to their lighter co-twins can be as much as half a SD in ...
Lynnea Myers about her JCPP Advances paper on Behavioural and Biological Divergence in Monozygotic Twin Pairs Discordant for ... So overall, what we found is that the current state of research on these monozygotic twins who are discordant for autism is ... There is a dearth of studies examining monozygotic ASD discordant twins, and Lynnea explains why this group is so important for ... More studies are needed, but more studies really are needed using these monozygotic discordant twins for things like autism or ...
METHOD: Thirty healthy, never-depressed monozygotic (MZ) twins with a co-twin history of depression (high risk group: n = 13) ... RESULTS: High-risk twins showed increased neural response to happy and fearful faces in dorsal anterior cingulate cortex (ACC ... These task-related changes in neural responses in high-risk twins were accompanied by impaired gender discrimination ... or without co-twin history of depression (low-risk group: n = 17) were enrolled in a functional magnetic resonance imaging ( ...
Endometriosis in monozygotic twins. Fertil Steril. 1997 Nov. 68(5):941-2. [QxMD MEDLINE Link]. ...
TMD-Twin presented an internal locus of control. CONCLUSION:. Both monozygotic twins presented a chronic pain phenotype, ... The design of research with monozygotic twins discordant for the disease has emerged as a powerful tool for the detection of ... The aim of this study is to report a clinical case of monozygotic twins discordant for pain-related temporomandibular joint ... Phenotypic analysis of discordant monozygotic twins for pain-related temporomandibular joi Phenotypic analysis of discordant ...
... we investigated a single pair of handedness discordant monozygotic (MzHd) twins. Imaging of the brain was undertaken using ... The twins were discordant for MRI anatomical asymmetries of the pars triangularis and planum temporale, whose asymmetry was ... Thus, the right-handed twin had left lateralized verbal with right lateralized visuo-spatial attention, while the left-handed ... twin had right lateralized verbal with left lateralized visuo-spatial activation; these data lend further support for to the ...
A Preliminary Case of Daily School Feelings in Monozygotic Twins. / Zheng, Yao; Molenaar, Peter C.M.; Arden, Rosalind et al. In ... A Preliminary Case of Daily School Feelings in Monozygotic Twins. In: Behavior Genetics. 2016 ; Vol. 46, No. 5. pp. 705-717. ... A Preliminary Case of Daily School Feelings in Monozygotic Twins. Behavior Genetics. 2016 Sep 1;46(5):705-717. doi: 10.1007/ ... A Preliminary Case of Daily School Feelings in Monozygotic Twins. Yao Zheng, Peter C.M. Molenaar, Rosalind Arden, Kathryn ...
Objective.-The study of monozgotic twins can elucidate possible environmental causes for a disease in genetically identical ... To this end, we studied a pair of monozygotic female twins appearing discordant for dementia of the Alzheimer type (DAT). ... Participants. -An 81-year-old female monozygotic twin pair.. Outcome Measures. -Clinical assessments, standardized rating ... Moreover, review of previous reports of monozygotic twin pairs concordant or discordant for Alzheimers disease, with adequate ...
When twins have significant differences in body mass index, the higher BMI more commonly veers from the genetically predicted ... Of the twins, 34% were monozygotic twins. They were examined at approximately age 30 in 1975 and then followed up in 1981, 1990 ... The study included 3227 twin pairs of the same gender from the Older Finnish Twin Cohort, consisting of twins born before 1958 ... Among the twin pairs, the twin with the higher BMI of the two more frequently deviated from their genetically predicted BMI ( ...
Method Data for 3,948 participants came from the Colombo Twin and Singleton Follow-up Study (CoTaSS-2). Using self-report ... but there is limited twin research exploring this association further. There is also little evidence on sex differences and non ... measures of depressive symptoms and HRQL, we conducted univariate and bivariate sex-limitation twin analyses. Results ... Twin studies report genetic and individual-level environmental underpinnings in the aetiology of both depression and HRQL, ...
N2 - We report on a pair of male monozygotic twins, one unaffected and the other affected with gonadotropin-releasing hormone ( ... AB - We report on a pair of male monozygotic twins, one unaffected and the other affected with gonadotropin-releasing hormone ( ... We report on a pair of male monozygotic twins, one unaffected and the other affected with gonadotropin-releasing hormone (GnRH ... Treatment with a gonadotropin-releasing-hormone analog and attainment of full height potential in a male monozygotic twin with ...
This study shows the presence of differentially expressed proteins in the saliva of the couple of monozygotic twins discordant ... we used a proteomic approach to evaluate the global changes in the salivary profile in a couple of monozygotic twins who were ... The aim was to evaluate differences of salivary protein expression in the CFS patient in respect to his healthy twin. Saliva ... Nevertheless, a recent study of Byrnes et al.[22] on monozygotic twins discordant for CFS, did not identify a biomarker for CFS ...
T2 - Genome-wide analysis of DNA methylation, copy number variation, and gene expression in monozygotic twins discordant for ... title = "Corrigendum: Genome-wide analysis of DNA methylation, copy number variation, and gene expression in monozygotic twins ... Corrigendum: Genome-wide analysis of DNA methylation, copy number variation, and gene expression in monozygotic twins ... Corrigendum: Genome-wide analysis of DNA methylation, copy number variation, and gene expression in monozygotic twins ...
... twin pairs, 101 monozygotic male (MZM) twin pairs, 96 dizygotic female (DZF) twin pairs, 73 dizygotic male (DZM) twin pairs, ... A was constrained to be 1 for the monozygotic (MZ) twin pairs and 0.5 for the dizygotic (DZ) twin pairs. C was constrained to ... Studies on Finnish twins and twin families. Twin Research, 5, 366-371.Google Scholar ... Kaprio, J. (2013). The Finnish Twin Cohort study: An update. Twin Research and Human Genetics, 16, 157-162.Google Scholar ...
  • Among numerous causes, premature ovarian failure (POF) frequently has a genetic aetiology and normal menopausal age is strongly heritable judging by the greater concordance between monozygotic (MZ) than dizygotic twins (Snieder et al. (infertile.com)
  • By integrating data on the immune profiles of healthy monozygotic and dizygotic twin pairs, we estimated the variance in CD25 expression by helper T cells displaying a naive phenotype to be largely driven by genetic and shared early environmental influences. (nature.com)
  • Whole-exome sequencing was performed for the twin pair that had discordance of aortic valve and aortic aneurysm. (elsevierpure.com)
  • Sexual discordance in monozygotic twins. (nih.gov)
  • The twins' varied life histories suggest that environmental risk factors may contribute to apparent discordance for DAT and possible delay in disease onset for the currently nondemented twin. (jamanetwork.com)
  • Discordance for skeletal and cardiac defect in monozygotic twins. (thejcdp.com)
  • OBJECTIVE: To analyze genetic differences between 2 pairs of monozygotic twins that had discordant aortic valve morphology, with 1 twin in each pair having a BAV and the other having a trileaflet aortic valve. (elsevierpure.com)
  • MAIN OUTCOMES AND MEASURES: Genetic coding variations between monozygotic twins using whole-exome sequencing and targeted gene sequencing. (elsevierpure.com)
  • Genetic sequencing methods identified no pathogenic sequence changes between the twins in each pair. (elsevierpure.com)
  • 3 Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH, UK. (nih.gov)
  • Twin studies report genetic and individual-level environmental underpinnings in the aetiology of both depression and HRQL, but there is limited twin research exploring this association further. (plos.org)
  • A novel study of twins who have significant intrapair differences in body mass index (BMI) shows that in the majority of cases, the twin with the higher BMI is the one that veers from their genetic predisposition, based on a polygenic risk score (PRS) for BMI. (medscape.com)
  • While previous studies have evaluated curious cases of differences in weight between twins, the study is unique in investigating whether the higher or lower weighted twin deviates from their genetic predisposition. (medscape.com)
  • Here we investigated the peripheral immune signatures of 61 monozygotic twin pairs discordant for MS to dissect the influence of genetic predisposition and environmental factors. (nature.com)
  • Nonetheless, the expanding helper T cells of twins with MS, which were also elevated in non-twin patients with MS, emerged independent of the individual genetic makeup. (nature.com)
  • Here we conducted an in-depth pairwise analysis of the systemic immune compartment of 61 monozygotic twin pairs discordant for MS, in which both siblings carry the same genetic and early-life environmental risk for the disease, yet only one is affected by MS. This approach thus eliminated the majority of bias attributed to variable genetic and early environmental influences in a heterogenous population 17 , 18 . (nature.com)
  • M any scientists once believed that physical similarities between identical twins are genetic, while their personalities, intelligence and other differences between them are an effect of their environment. (youdao.com)
  • You look at identical twins , monozygotic twins who share the same genetic profile. (youdao.com)
  • The study was a heritability analysis of 192 pairs of twins, which attributed 37 percent of the variation in risk of autism to genetic factors and 55 percent to shared environmental factors . (cdc.gov)
  • Method: Four dermatoglyphic markers of prenatal growth were obtained by established procedures from 26 monozygotic twin pairs discordant for schizophrenia, 13 monozygotic twin pairs concordant for schizophrenia, and several normal monozygotic twin samples. (missouristate.edu)
  • Nongenetic pathologic developments of brain-wave patterns in monozygotic twins discordant and concordant for schizophrenia. (uni-heidelberg.de)
  • Yet our investigations into mz twins discordant and concordant for schizophrenia yielded a significantly reduced within-pair EEG concordance for both, the pairs discordant for schizophrenia and the pairs concordant for schizophrenia (with concordance for schizophrenia assessed through a syndrome-oriented approach). (uni-heidelberg.de)
  • Consequently, EEG anomalies associated with schizophrenia and manifested differently in the mz co-twins concordant for schizophrenia are likely the effect of nongenetic, pathologic processes that evolved independently in the co-twins' genetically identical brains once the illness began to progress. (uni-heidelberg.de)
  • Objective: This co-twin study investigated monozygotic twins who were discordant for schizophrenia for evidence of prenatal growth differences between the affected and well co-twins. (missouristate.edu)
  • Results: The a-b ridge count differences between the affected and well co-twins were greater than those found for concordant and normal monozygotic pairs. (missouristate.edu)
  • In contrast, no significant differences were found between the affected twins and their well co-twins on markers associated with fetal development before 13 or after 15 weeks estimated gestational age. (missouristate.edu)
  • The main differences were the lower pressure pain threshold and higher hyperalgesia locally presented by TMD- Twin . (bvsalud.org)
  • The aim was to evaluate differences of salivary protein expression in the CFS patient in respect to his healthy twin. (biomedcentral.com)
  • Cite this: Differences in Twins Suggest Obesity Veers From Genetics - Medscape - Nov 21, 2023. (medscape.com)
  • Brain structural differences in monozygotic twins discordant for body mass index. (mpg.de)
  • In particular, the within-pair EEG concordance of monozygotic (mz) twins was found to be typically as high as r = 0.81 across channels and frequency bands, thus being comparable to that between repeated assessments on the same individual with typically r = 0.83. (uni-heidelberg.de)
  • A series of monozygotic (MZ) twin pairs discordant for premature ovarian failure presented an unusual opportunity to study ovarian transplantation . (infertile.com)
  • The aim of this study was to investigate the relationship between poor motor ability and anxious and depressive symptomatology in child and adolescent monozygotic twins. (edu.au)
  • METHOD: Thirty healthy, never-depressed monozygotic (MZ) twins with a co-twin history of depression (high risk group: n = 13) or without co-twin history of depression (low-risk group: n = 17) were enrolled in a functional magnetic resonance imaging (fMRI) study. (ox.ac.uk)
  • Our study considered whether children who do not reach their potential birthweight, as indexed by the weight of their heavier twin, also do not attain their potential IQ. (uel.ac.uk)
  • We had quite a few when we initially pulled the articles on this kind of topic, but we determined studies to be eligible if they used this co-twin control design, and that's where you have a pair of twins participate in a study, and for our review, we were specifically looking at twins that were discordant for autism, clinical symptoms, or traits. (acamh.org)
  • The aim of this study is to report a clinical case of monozygotic twins discordant for pain -related temporomandibular joint disorder (TMD) from a cognitive-behavioral-emotional phenotypic analysis , from the comparison of clinical variables of pain , history of exposure to painful procedures in early childhood, and coping with pain . (bvsalud.org)
  • In the present study, we used a proteomic approach to evaluate the global changes in the salivary profile in a couple of monozygotic twins who were discordant for CFS. (biomedcentral.com)
  • This study shows the presence of differentially expressed proteins in the saliva of the couple of monozygotic twins discordant for CFS, probably related to the disease. (biomedcentral.com)
  • note = "Funding Information: The authors gratefully acknowledge the ongoing contribution of the{\^A} participants{\^A} in the Twins Early Development Study (TEDS){\^A} and their families. (psu.edu)
  • The study of monozgotic twins can elucidate possible environmental causes for a disease in genetically identical subjects. (jamanetwork.com)
  • Data for 3,948 participants came from the Colombo Twin and Singleton Follow-up Study (CoTaSS-2). (plos.org)
  • The Colombo Twin and Singleton study was funded in whole, or in part, by the Wellcome Trust [Grant number 093206/Z/10/Z], https://wellcome.org . (plos.org)
  • The study included 3227 twin pairs of the same gender from the Older Finnish Twin Cohort, consisting of twins born before 1958 and alive in 1974 in Finland. (medscape.com)
  • Conversely, a registry-based study investigated the familial recurrence rate of MS and revealed that monozygotic twin pairs displayed the highest familial risk (17% age-adjusted risk for the unaffected twin) of developing MS, indicating a strong heritable effect 8 . (nature.com)
  • A monozygotic co-twin control study in men. (erowid.org)
  • The obese brain as a heritable phenotype: A combined morphometry and twin study. (mpg.de)
  • The first study asks if health and educational attainment are related within monozygotic twin (MZ) pairs. (lu.se)
  • Among the twin pairs, the twin with the higher BMI of the two more frequently deviated from their genetically predicted BMI (approximately two thirds) compared with the lower-weight twin, while those who were the lower weight of the two deviated from their predicted BMI approximately a third of the time. (medscape.com)
  • Together, our matched-pair analysis of the extended twin approach allowed us to discern genetically and environmentally determined features of an MS-associated immune signature. (nature.com)
  • eg, bone, bone marrow, and skin grafts) Genetically identical (syngeneic [between monozygotic twins]) donor tissue (isografts) Genetically. (msdmanuals.com)
  • Monozygotic twin girls are reported, one of whom has the typical clinical features of Duchenne muscular dystrophy despite a normal female karyotype. (bmj.com)
  • This segregation was followed by, and may even have resulted in, twinning into a female pair, one normal and one with the full clinical features of the disease. (bmj.com)
  • In each pair, the twin with a BAV underwent surgical aortic valve replacement for clinical indications. (elsevierpure.com)
  • Discordant Clinical Outcomes in a Monozygotic Dichorionic-Diamniotic Twin Pregnancy with Early Zika Virus Exposure. (cdc.gov)
  • A pair of monozygotic male twins discordant for ectopia vesicae urinariae is described. (bmj.com)
  • We take a microgenetic approach to investigate the issue, illustrated by the analysis of an episode between a pair of male twin children and their grandpa. (bvsalud.org)
  • We report on a pair of male monozygotic twins, one unaffected and the other affected with gonadotropin-releasing hormone (GnRH)-dependent precocious puberty, and discuss the role of treatment with a GnRH analog in the attainment of full height potential in GnRH-dependent precocious puberty. (elsevierpure.com)
  • A monozygotic co-twin control design was used to compare the health of former heavy marijuana using male monozygotic twins to that of their co-twins who never used marijuana significantly. (erowid.org)
  • We performed an intrapair comparison in 27 monozygotic twin pairs, one of whom was taking third-generation OC, whereas the other was not using OC. (maastrichtuniversity.nl)
  • Results indicated significantly higher levels of anxious and depressive symptomatology in twins with a motor disorder in discordant pairs compared to their co-twins without a motor disorder, and controls. (edu.au)
  • In comparison with their well co-twins, the affected twins, in discordant pairs, had developed fewer epidermal ridges in the a-b interdigital area of their right palms. (missouristate.edu)
  • It was remarkable, therefore, to identify a MZ twin pair in which one sister had undergone menopause for unexplained reasons at age 14 years, whereas the other, aged 24, was still fertile with three naturally conceived children, as well as normal ovulatory cycles and ovarian reserve (Silber et al. (infertile.com)
  • Crossed cerebral lateralization for verbal and visuo-spatial function in a pair of handedness discordant monozygotic twins: MRI and fMRI brain imaging. (ox.ac.uk)
  • To examine the nature of hemispheric lateralization for neural processes underlying verbal fluency and visuo-spatial attention, we investigated a single pair of handedness discordant monozygotic (MzHd) twins. (ox.ac.uk)
  • To this end, we studied a pair of monozygotic female twins appearing discordant for dementia of the Alzheimer type (DAT). (jamanetwork.com)
  • An 81-year-old female monozygotic twin pair. (jamanetwork.com)
  • Fifty-six marijuana use discordant monozygotic twin pair members of the Vietnam Era Twin (VET) Registry. (erowid.org)
  • For example, I have used data on monozygotic (or 'identical') twins to analyze if the extent to which mothers read to children affect children's academic performance. (ku.dk)
  • DESIGN, SETTING, AND PARTICIPANTS: Two pairs of twins that were objectively determined to be monozygotic were examined at a tertiary care medical center associated with an academic medical center. (elsevierpure.com)
  • Using self-report measures of depressive symptoms and HRQL, we conducted univariate and bivariate sex-limitation twin analyses. (plos.org)
  • Roux-en-Y gastric bypass surgery progressively alters radiologic measures of hypothalamic inflammation in obese patients. (mpg.de)
  • Both monozygotic twins presented a chronic pain phenotype , although they were discordant with the TMD-related pain . (bvsalud.org)
  • Control- Twin did not show TMD, however she presented other chronic pains . (bvsalud.org)
  • Many times, the results of this test are the first indication that this is a twin pregnancy. (twinslist.org)
  • Here we present a case of conjoined twins in a triplet pregnancy diagnosed at 13 of weeks gestation. (hindawi.com)
  • This case represents to our knowledge the only MRI images of conjoined twins in a triplet pregnancy and demonstrates how 3D imaging can be used to better counsel patients about management options. (hindawi.com)
  • Conjoined twins within a triplet pregnancy are very rare and a recent review suggested the incidence is less than one in a million deliveries [ 3 ]. (hindawi.com)
  • The purpose of this report is to describe the presentation and management of a dichorionic triplet pregnancy complicated by conjoined twins. (hindawi.com)
  • MRI images of conjoined twins in a triplet pregnancy. (hindawi.com)
  • The parents were counseled and options discussed included (1) continue the pregnancy understanding that the shared heart meant the conjoined twins could not be separated should they survive to delivery, (2) terminate the entire pregnancy or, (3) selective feticide of the conjoined twins. (hindawi.com)
  • A review published in 2003 reported thirteen cases of conjoined twins within a triplet pregnancy [ 2 ]. (hindawi.com)
  • The first familial cases were reported in twins by Rosen and subsequently in 8 persons from a large 3-generation pedigree reported by Pipkin. (medscape.com)
  • 1984). We have encountered a conjoined stillborn twin fetas. (ivis.org)
  • METHODS: Ten MZ twin pairs requested ovarian transplantation and eight have undergone transplantation with cryopreservation of spare tissue. (infertile.com)
  • 2005). After the sterile twin received a graft of ovarian tissue from her sibling, she conceived naturally during the second menstrual cycle, and delivered a healthy baby at full-term. (infertile.com)
  • Shared fetal heart of conjoined twins. (hindawi.com)
  • A repeat scan was performed four days later again confirming a viable singleton gestation with fetal demise of conjoined twins. (hindawi.com)
  • There has been no real doubt that human homologous or identical twins come from the division of a single egg. (edu.au)
  • She couldn't tell the difference between the identical twins. (youdao.com)
  • N-COUNT Identical twins are twins of the same sex who look exactly the same. (youdao.com)
  • One of her most famous photographs is called " Identical Twins . (youdao.com)
  • But what if you are able to find identical twins who were separated at birth, and reared in radically different environments. (youdao.com)
  • It even distinguished between identical twins--their genes are the same, but their irises aren't. (youdao.com)
  • The developing embryo starts to split into identical twins within the first two weeks after conception. (youdao.com)
  • And it is only a predisposition towards having non-identical twins that is passed down through families. (youdao.com)
  • A thirty-two-year-old gravida 1 para 0 was referred to High Risk Obstetrics with a diagnosis of dichorionic diamniotic twin gestation. (hindawi.com)
  • An early ultrasound at six weeks gestation was reported as a dichorionic diamniotic twin gestation. (hindawi.com)
  • This case of discordant twins is not unique, however, and nine other twin pairs have subsequently consulted our center for ovarian transplantation in preference to conventional oocyte donation . (infertile.com)
  • Different neural and cognitive response to emotional faces in healthy monozygotic twins at risk of depression. (ox.ac.uk)
  • TMD- Twin was more exposed to painful procedures and emotional events due to congenital heart problems. (bvsalud.org)
  • Conclusions: Because the a-b ridges are known to complete development between 13 and 15 weeks estimated gestational age, the results provide physical evidence suggesting that the schizophrenia-affected monozygotic twins alone experienced a time-specific and time-limited dysgenesis during this time. (missouristate.edu)
  • We examined whether sub-optimal intra-uterine growth relates to impaired cognitive outcome by comparing birthweight and cognition in monozygotic (MZ) twins. (uel.ac.uk)
  • Beside the present case, the only other illustrative specimens among mammals are the normal developmental stages of the Texas armadillo (Newman and Patterson, '10) and Assheton's ('98) single case of a sheep's blastodermic vesicle which bore twin germinal areas. (edu.au)
  • CASE REPORT TMD- Twin presented a diagnosis of painful (myofascial pain with referral ) and joint (disk displacement with reduction) TMD according to the criteria of the DC/TMD. (bvsalud.org)
  • Restricting analyses to MZ twins enables the effect of reduced intra-uterine growth on cognition to be examined independently of confounding factors including parental IQ and education, gender, age, genes, and gestation. (uel.ac.uk)
  • Analysis of an X linked DNA polymorphism in 16 independent somatic cell hybrids made between cells derived from each girl and a mouse line suggest that in one twin only the maternal X chromosome is active, whereas in the other the active X was paternally derived. (bmj.com)
  • The cultural psychology approach demands a qualitative, systemic analysis of complexities of twin development, considering the dynamics of internalization processes taking place within culture, and across social relations with significant adults. (bvsalud.org)
  • Phenotypic analysis of discordant monozygotic twins for pain-related temporomandibular joint disorder. (bvsalud.org)
  • We combined the high-throughput of mass cytometry, facilitating the analysis of 57 twin pairs, with cellular indexing of transcriptomes and epitopes by sequencing (CITE-seq) of eight selected twin pairs to obtain a comprehensive overview of epitopes, transcriptome and T cell receptor (TCR) clonotypes. (nature.com)
  • The co-twin control design was used to explore these mental health issues in MZ twins concordant and discordant for a motor disorder, and controls. (edu.au)
  • The design of research with monozygotic twins discordant for the disease has emerged as a powerful tool for the detection of phenotypic risk factors . (bvsalud.org)
  • There is a dearth of studies examining monozygotic ASD discordant twins, and Lynnea explains why this group is so important for inclusion in research to advance the science into non-shared environmental effects, and explains the implications of the findings for professionals working in child and adolescent mental health. (acamh.org)
  • Person-specific non-shared environmental influences on intra-individual variability of daily school feelings were estimated using time series data from twenty-one pairs of monozygotic twins (age = 10 years, 16 female pairs) over two consecutive weeks. (psu.edu)
  • RESULTS: High-risk twins showed increased neural response to happy and fearful faces in dorsal anterior cingulate cortex (ACC), dorsomedial prefrontal cortex (dmPFC), pre-supplementary motor area and occipito-parietal regions compared to low-risk twins. (ox.ac.uk)
  • The results suggest that the mean advantage for heavier twins relative to their lighter co-twins can be as much as half a SD in VIQ points. (uel.ac.uk)
  • As the sample is taken from the mother's blood, there's no way to isolate the results for each twin. (twinslist.org)
  • 71 MZ twin pairs participated (7 years 11 months to 17 years 3 months). (uel.ac.uk)
  • At 1.6 years of age, the affected twin was studied for tall stature (+3.8 SD), and was diagnosed as having GnRH-dependent precocious puberty due to a hypothalamic hamartoma of the tuber cinereum. (elsevierpure.com)
  • He attained a final height of 171.0 cm at 14.9 years of age (+0.10 SD) and his twin 170.0 cm at 15.3 years of age (-0.10 SD), with their target height being 174.5 ± 9.0 cm. (elsevierpure.com)
  • A total of 1,240 Finnish twins aged 21-26 years completed a questionnaire containing items on the appraisal of their career goals along five dimensions: importance, progress, effort, strain, and self-efficacy. (cambridge.org)
  • This scan identified a triplet gestation complicated by a set of conjoined twins. (hindawi.com)
  • Moreover, review of previous reports of monozygotic twin pairs concordant or discordant for Alzheimer's disease, with adequate family history data, suggest a pattern indicating interactions among age at dementia onset, sex, and familiality. (jamanetwork.com)
  • Using complementary multimodal high-throughput and high-dimensional single-cell technologies in conjunction with data-driven computational tools, we identified an inflammatory shift in a monocyte cluster of twins with MS, coupled with the emergence of a population of IL-2 hyper-responsive transitional naive helper T cells as MS-related immune alterations. (nature.com)
  • The internal locus of control indicates greater pain sensitivity , with better coping of the painful experience for the TMD- Twin . (bvsalud.org)
  • These task-related changes in neural responses in high-risk twins were accompanied by impaired gender discrimination performance during face processing. (ox.ac.uk)
  • Conjoined twins are a rare complication of monozygotic twinning and are associated with high perinatal mortality. (hindawi.com)
  • Published reports concerning family incidence and twin reports are reviewed. (bmj.com)
  • The first of the two new specimens} consisted of a single chorionic sac which contained twin embryos, each 12.3 mm. long (fig. 1). (edu.au)
  • specimen of human twins demonstrates for the first time their actual origin from a single yolk sac, and hence from a single ovum. (edu.au)
  • Within the single chorion were twin embryos of 11.5 and 12 mm. (fig. 4). (edu.au)
  • Conjoined twins occur when division of a single zygote takes place twelve to thirteen days after fertilization [ 1 ]. (hindawi.com)
  • 1,000 fecal samples obtained from the TwinsUK population, including 416 twin pairs. (nih.gov)
  • There were significantly higher levels of anxious symptomatology in twins with a motor disorder in discordant sets than in sets of twins concordant for a motor disorder. (edu.au)
  • There were significantly higher levels of anxious symptomatology in concordant twins than in controls. (edu.au)
  • To the positive list I have there added two new cases of monochorial twins, each unique of its kind. (edu.au)