An organochlorophosphate cholinesterase inhibitor that is used as an insecticide for the control of flies and roaches. It is also used in anthelmintic compositions for animals. (From Merck, 11th ed)
Pesticides designed to control insects that are harmful to man. The insects may be directly harmful, as those acting as disease vectors, or indirectly harmful, as destroyers of crops, food products, or textile fabrics.

Metrifonate increases neuronal excitability in CA1 pyramidal neurons from both young and aging rabbit hippocampus. (1/36)

The effects of metrifonate, a second generation cholinesterase inhibitor, were examined on CA1 pyramidal neurons from hippocampal slices of young and aging rabbits using current-clamp, intracellular recording techniques. Bath perfusion of metrifonate (10-200 microM) dose-dependently decreased both postburst afterhyperpolarization (AHP) and spike frequency adaptation (accommodation) in neurons from young and aging rabbits (AHP: p < 0.002, young; p < 0.050, aging; accommodation: p < 0.024, young; p < 0.001, aging). These reductions were mediated by muscarinic cholinergic transmission, because they were blocked by addition of atropine (1 microM) to the perfusate. The effects of chronic metrifonate treatment (12 mg/kg for 3 weeks) on CA1 neurons of aging rabbits were also examined ex vivo. Neurons from aging rabbits chronically treated with metrifonate had significantly reduced spike frequency accommodation, compared with vehicle-treated rabbits. Chronic metrifonate treatment did not result in a desensitization to metrifonate ex vivo, because bath perfusion of metrifonate (50 microM) significantly decreased the AHP and accommodation in neurons from both chronically metrifonate- and vehicle-treated aging rabbits. We propose that the facilitating effect of chronic metrifonate treatment on acquisition of hippocampus-dependent tasks such as trace eyeblink conditioning by aging subjects may be caused by this increased excitability of CA1 pyramidal neurons.  (+info)

Treating neurocysticercosis medically: a systematic review of randomized, controlled trials. (2/36)

OBJECTIVE: To summarize the evidence from randomized controlled trials on the effects of cysticidal therapy used for treating human cysticercosis. METHODS: Published and unpublished studies in any language identified through MEDLINE (1966 - June 1999) specialized databases, abstracts, proceedings and contact with experts were analysed. Those which compared, using randomized or quasi-randomized methods, any cysticidal drug with placebo or symptomatic therapy were entered in the study. Data were extracted independently by two reviewers and trial quality assessed. Meta-analysis using fixed effects models calculated provided there was no significant heterogeneity, expressed as relative risk. RESULTS: Four trials met the inclusion criteria, treating intraparenchymatous neurocysticercosis with either albendazole or praziquantel compared to placebo or no treatment. In the two trials reporting clinical outcomes, treatment was not associated with a reduction in the risk of seizures, although numbers were small (RR 0.95, 95% CI 0.59-1.51). Four trials reported radiological outcomes, and cysticidal treatment was associated with a lower risk of cyst persistence of scans taken within six months of start of treatment (RR 0.83, 95% CI 0.70-0.99). Subsidiary analysis assuming different outcomes in patients lost to follow-up did not alter the findings of the main analysis. CONCLUSIONS: There is insufficient evidence to determine whether cysticidal therapy is of any clinical benefit to patients with neurocysticercosis. The review does not exclude the possibility that more patients remain seizure-free when treated with cysticidal drugs. Further testing through placebo-controlled trials is required.  (+info)

Trichlorfon induces spindle disturbances in V79 cells and aneuploidy in male mouse germ cells. (3/36)

In order to assess the effects of trichlorfon on cell division and on aneuploidy induction, we conducted an in vitro assay for spindle disturbances using V79 cells and an in vivo assay for aneuploidy induction in meiosis of male mice using multicolour fluorescence in situ hybridization (FISH) with epididymal sperm. In the in vitro assay, the chemical caused a concentration-dependent increase in the incidence of initial and full c-mitoses in the dose range 40-120 microg/ml trichlorfon. The mitotic index (MI) was decreased between 40 and 100 microg/ml trichlorfon, whereas at 120 microg/ml the MI was back to the control level, coinciding with the dramatic increase in c-mitoses. The results confirm that trichlorfon is a potent spindle poison in V79 cells. In the in vivo multicolour FISH assay, administration of trichlorfon to male mice at single doses of 200, 300 and 405 mg/kg caused a dose-dependent increase of the frequencies of disomic sperm (0.068, 0.074 and 0.134%, respectively) compared with the corresponding controls (0.046, 0.042 and 0.056%, respectively). The prevalence of X-X-8 and Y-Y-8 sperm suggests that trichlorfon affected chromosome segregation predominantly during the second meiotic division. Diploid sperm were not induced by trichlorfon treatment, indicating that no meiotic block occurred. It is concluded that trichlorfon is a potent spindle poison in V79 cells and induces aneuploidy in mouse spermatocytes during meiosis.  (+info)

Metrifonate decreases sI(AHP) in CA1 pyramidal neurons in vitro. (4/36)

Metrifonate, a cholinesterase inhibitor, has been shown to enhance learning in aging rabbits and rats, and to alleviate the cognitive deficits observed in Alzheimer's disease patients. We have previously determined that bath application of metrifonate reduces the spike frequency adaptation and postburst afterhyperpolarization (AHP) in rabbit CA1 pyramidal neurons in vitro using sharp electrode current-clamp recording. The postburst AHP and accommodation observed in current clamp are the result of four slow outward potassium currents (sI(AHP), I(AHP), I(M), and I(C)) and the hyperpolarization activated mixed cation current, I(h). We recorded from visually identified CA1 hippocampal pyramidal neurons in vitro using whole cell voltage-clamp technique to better isolate and characterize which component currents of the AHP are affected by metrifonate. We observed an age-related enhancement of the slow component of the AHP tail current (sI(AHP)), but not of the fast decaying component of the AHP tail current (I(AHP), I(M), and I(C)). Bath perfusion of metrifonate reduced sI(AHP) at concentrations that cause a reduction of the AHP and accommodation in current-clamp recordings, with no apparent reduction of I(AHP), I(M), and I(C). The functional consequences of metrifonate administration are apparently mediated solely through modulation of the sI(AHP).  (+info)

Short- and long-term effect of acetylcholinesterase inhibition on the expression and metabolism of the amyloid precursor protein. (5/36)

We have investigated the acute and chronic effect of metrifonate (MTF) and dichlorvos (DDVP), respectively the prodrug and active acetylcholinesterase inhibitor, on the secretory processing of the amyloid precursor protein (APP) in SH-SY5Y neuroblastoma cells. We demonstrate that the acute treatment of SH-SY5Y cells with both compounds results in an increased secretion of the soluble fragment of APP (sAPPalpha) into the conditioned media of cells, with a pattern correlated to the level of acetycholinesterase inhibition. The regulation of APP processing in these conditions is mediated by an indirect cholinergic effect on muscarinic receptors, as demonstrated by inhibition with atropine. We have also followed APP expression and metabolism after long-term treatment with metrifonate. Treated cells showed reduced AChE activity after 24, 48 h and also following 7 days of repeated treatment, a time point at which increased AChE expression was detectable. At all time points sAPPalpha release was unaffected suggesting that enhanced sAPPalpha release by MTF is transitory, nevertheless the sensitivity of cholinergic receptors was unchanged, as indicated by the fact that cholinergic response can be elicited similarly in untreated and treated cells. APP gene expression was unaffected by long-term AChE inhibition suggesting that increased short-term sAPPalpha release does not elicit compensatory effects.  (+info)

Galantamine is an allosterically potentiating ligand of neuronal nicotinic but not of muscarinic acetylcholine receptors. (6/36)

Galantamine (Reminyl), an approved treatment for Alzheimer's disease (AD), is a potent allosteric potentiating ligand (APL) of human alpha 3 beta 4, alpha 4 beta 2, and alpha 6 beta 4 nicotinic receptors (nAChRs), and of the chicken/mouse chimeric alpha 7/5-hydroxytryptamine3 receptor, as was shown by whole-cell patch-clamp studies of human embryonic kidney-293 cells stably expressing a single nAChR subtype. Galantamine potentiates agonist responses of the four nAChR subtypes studied in the same window of concentrations (i.e., 0.1-1 microM), which correlates with the cerebrospinal fluid concentration of the drug at the recommended daily dosage of 16 to 24 mg. At concentrations >10 microM, galantamine acts as an nAChR inhibitor. The other presently approved AD drugs, donepezil and rivastigmine, are devoid of the nicotinic APL action; at micromolar concentrations they also block nAChR activity. Using five CHO-SRE-Luci cell lines, each of them expressing a different human muscarinic receptor, and a reporter gene assay, we show that galantamine does not alter the activity of M1-M5 receptors, thereby confirming that galantamine modulates selectively the activity of nAChRs. These studies support our previous proposal that the therapeutic action of galantamine is mainly produced by its sensitizing action on nAChRs rather than by general cholinergic enhancement due to cholinesterase inhibition. Galantamine's APL action directly addresses the nicotinic deficit in AD.  (+info)

Experimental study of the effect of a series of phosphoroorganic pesticides (Dipterex and Imidan) on embryogenesis. (7/36)

Experiments conducted on pregnant Wistar rats show that chlorophos (Dipterex) has embroyotoxic and teratogenic effects after oral introduction in a 80 mg/kg dose during a critical period of embryogenesis. Embryotoxic and teratogenic effects are absent during the introduction of 8 mg/kg of the pesticide. The oral introduction of phthalophos (Imidan) in a 30 mg/kg dose once on day 9 of pregnancy and the introduction of a 1.5 mg/kg dose daily throughout the course of pregnancy caused increased postimplantation mortality of embryos. A dose of 30 mg/kg of phthalophos on day 9 or day 13 of pregnancy causes developmental abnormalities, including hyponathia and hydrocephaly. A 0.06 mg/kg phthalophos dose does not affect the course of embryogenesis in white rats. Thus the organophosphate pesticides Dipterex and Imidan exhibit embryotoxic and teratogenic effects at doses which significantly exceed the acutal amounts of the pesticide that can enter the human organism.  (+info)

Cloning, mutagenesis, and expression of the acetylcholinesterase gene from a strain of Musca domestica; the change from a drug-resistant to a sensitive enzyme. (8/36)

Insect acetylcholinesterase (AChE) is known to be a primary target of organophosphorus and carbamate insecticides. However chronic exposure to these chemicals has led to resistance to applied insecticides, due usually to mutation of the AChE gene. Analysis of the AChE gene (hm) of Musca domestica (the housefly), which is cloned in this report, reveals the relationship between mutation and insecticide resistance. The 2,076 bp hm encodes a mature protein of 612 amino acids (67 kDa), and an 80 residue signal peptide. Unlike the enzyme of 'sensitive' strains, the AChE used in this study was resistant to the organophosphorus insecticide, trichlorphon. DNA sequencing showed that this AChE is identical to that of the sensitive strains with the exception of three amino acids Met-82, Ala-262, and Tyr-327. Site-directed mutagenesis of the Ala-262 and Tyr-327 residues largely restored sensitivity to the insecticide, suggesting that these two residues are the key structural elements controlling sensitivity. In addition to these residues, Glu-234 and Ala-236 in the conserved sequence FGESAG are thought to play a role in modulating sensitivity to organophosphorus insecticides.  (+info)

Trichlorfon is an organophosphate insecticide and acaricide. It is used to control a wide variety of pests, including flies, ticks, and mites in agriculture, livestock production, and public health. Trichlorfon works by inhibiting the enzyme acetylcholinesterase, which leads to an accumulation of the neurotransmitter acetylcholine and results in paralysis and death of the pest. It is important to note that trichlorfon can also have harmful effects on non-target organisms, including humans, and its use is regulated by various governmental agencies to minimize potential risks.

Insecticides are substances or mixtures of substances intended for preventing, destroying, or mitigating any pest, including insects, arachnids, or other related pests. They can be chemical or biological agents that disrupt the growth, development, or behavior of these organisms, leading to their death or incapacitation. Insecticides are widely used in agriculture, public health, and residential settings for pest control. However, they must be used with caution due to potential risks to non-target organisms and the environment.

Trichlorfon/metrifonate was banned in New Zealand in 2011. Trichlorfon/metrifonate was banned in India from 2020. "Trichlorfon ... Trichlorfon/metrifonate was banned in the EU in 2008 (Regulation (EC) 689/2008) and in Brazil in 2010. Trichlorfon/metrifonate ... "Trichlorfon Facts". Pesticides: Reregistration. U.S. Environmental Protection Agency. "Trichlorfon". R.E.D. Facts. U.S. ... "Reregistration Eligibility Decision Trichlorfon" (PDF). Retrieved 2018-08-09. "Decision Guidance Document Trichlorfon - ...
Botflies can be controlled with several types of dewormers, including dichlorvos, ivermectin, and trichlorfon. In cattle, the ...
Malathion, methoxychlor, phosmet, trichlorfon, and synthetic pyrethroids (permethrin) are registered by EPA but are used ...
Researchers have suggested a mix of trichlorfon and urine to combat C. mantispoides as a pest; the urine lures the grasshoppers ...
Chemicals such as trichlorfon and chlorpyrifos, cypermethrin and lambda-cyhalothrin can be applied as soil drenches. ...
Prior to development of these drugs, during the 1950s and 1960s, treatment with piperazine, dichlorvos and trichlorfon was used ...
If the outbreak is heavy, insecticides such as trichlorfon, chlorfluazuron or tebufenozide can be applied to eradicate immature ...
Insecticides including malathion, parathion, diazinon, fenthion, dichlorvos, chlorpyrifos, ethion, trichlorfon Nerve agents ...
Gyrodactylus infections in fish tanks can be treated using a combination of formalin, trichlorfon and praziquantel for a ...
... tralomethrin transfluthrin transpermethrin triamiphos triarathene triazamate triazophos trichlophenidine trichlorfon ...
... trichlorfon MeSH D02.705.670.243 - cyclophosphamide MeSH D02.705.670.243.250 - ifosfamide MeSH D02.705.676.700 - phosphites ...
... corresponding to paraquat ion at or above 200 g/L Trichlorfon As of October 2018, the convention has 161 parties, which ...
Toxins derived from Fusarium sporotrichioides Trichlorfon Trichloroacetonitrile 1,1,2-Trichloroethane Triethanolamine ...
Created: 1990-03-20T00:00:00Z. Last modified: 2021-05-24T17:34:42Z. skos:notation: 31520. void:inDataset: http://aims.fao.org/aos/agrovoc/void.ttl#Agrovoc ...
... and Supplier of Trichlorfon in Zibo. Contact us Now to know more about Trichlorfon ...
Trichlorfon. by World Health Organization , International Programme on Chemical Safety.. Series: Environmental health criteria ... Trichlorfon : health and safety guide. by World Health Organization , International Programme on Chemical Safety. ...
Market also known as the Trichlorfon market, refers to the global industry involved in the production, distribution ... 90% Trichlorfon TC. • 97% Trichlorfon TC. • Others. Global Dipterex (Trichlorfon) Market: By Application. • Insecticide for ... Dipterex (Trichlorfon) Market also known as the Trichlorfon market, refers to the global industry involved in the production, ... Dipterex (Trichlorfon) Market Overview Analysis, Trends, Share, Size, Type & Future Forecast to 2032. July 14, 2023. - by ...
Commission Regulation (EC) No 1213/2008 of 5 December 2008 concerning a coordinated multiannual Community control programme for 2009, 2010 and 2011 to ensure compliance with maximum levels of and to assess the consumer exposure to pesticide residues in and on food of plant and animal origin (Text with EEA relevance). Commission Regulation (EC) No 1213/2008 of 5 December 2008 concerning a coordinated multiannual Community control programme for 2009, 2010 and 2011 to ensure compliance with maximum levels of and to assess the consumer exposure to pesticide residues in and on food of plant and animal origin (Text with EEA relevance). Commission Regulation (EC) No 1213/2008 of 5 December 2008 concerning a coordinated multiannual Community control programme for 2009, 2010 and 2011 to ensure compliance with maximum levels of and to assess the consumer exposure to pesticide residues in and on food of plant and animal origin (Text with EEA relevance). OJ L 328, 6.12.2008, p. 9-17 (BG, ES, CS, DA, DE, ET, ...
10] The compounds most frequently involved include malathion, dichlorvos, trichlorfon, and fenitrothion/malathion. ...
Fenitrothion, trichlorfon, and chlorphenamidine. Alphamethrin. Bacillus thuringiensis kurstaki. Tebufenozide. 1972. 10,000. 0. ...
Dispatch of Decision Guidance Documents and request for submission of import responses on carbofuran; trichlorfon; short-chain ...
Trichlorfon/metrifonate was banned in New Zealand in 2011. Trichlorfon/metrifonate was banned in India from 2020. "Trichlorfon ... Trichlorfon/metrifonate was banned in the EU in 2008 (Regulation (EC) 689/2008) and in Brazil in 2010. Trichlorfon/metrifonate ... "Trichlorfon Facts". Pesticides: Reregistration. U.S. Environmental Protection Agency. "Trichlorfon". R.E.D. Facts. U.S. ... "Reregistration Eligibility Decision Trichlorfon" (PDF). Retrieved 2018-08-09. "Decision Guidance Document Trichlorfon - ...
It is also manufactured by heating a chemical called trichlorfon. In 1984, about 1 million pounds of dichlorvos was ...
Beyond Pesticides, November 5, 2018) As you know, the stakes in this midterm election are high. Many races are too close to call and will be decided by voter turnout. As we have read, our vote will make a difference!. The stakes are high. People and the environment are being poisoned. Pollinators are disappearing. Waterways are being contaminated. Biodiversity is threatened. Children -especially farmworker children-are suffering brain damage, and pesticide exposure is linked to the increase in ADHD and autism. Pesticide exposure is implicated in cancer, Parkinsons disease, reproductive dysfunction, diabetes, learning disabilities, and more.. We need people in elected positions - from local officials to national offices - who will listen to constituents who know the need for protection from pesticides and understand the urgent need to adopt of organic practices. Learn about your candidates and vote!. What more we can do. Take someone with you to the polls. Offer assistance to your neighbors who ...
Beyond Pesticides, August 12, 2009) A new study examining the effects of the mosquito repellent DEET on insects, mice and human proteins reports that the chemical interferes with a prominent central nervous system enzyme. This effect is magnified when exposure to DEET is combined with exposure to certain other pesticides.. Entitled, "Evidence for inhibition of cholinesterases in insect and mammalian nervous systems by the insect repellent deet," and published in BioMed Central (BMC) Biology, the study utilized toxicological, biochemical and electrophysiological techniques to show that DEET is not simply a behavior-modifying chemical, but that it also inhibits cholinesterase activity in both insect and mammalian neuronal preparations. The researchers examined DEETs effects on mosquitoes, cockroach nerves, mouse muscles, and enzymes purified from fruit flies and humans. Applications of DEET slowed or halted the actions of the enzyme acetylcholinesterase. This enzyme is crucial for regulating ...
Use of Trichlorfon for snail treatment; caution be exercised when Trichlorfon is used for the removal of snails (or if snails ... But Trichlorfon remains stable in the same pond water held under acidic (pH 5.0) conditions for 2 hours.. Trichlorfon is highly ... and increasing toxicity of Trichlorfon which may result in the death of fish as well.. Trichlorfon is best used in water with ... In fact, the use of Trichlorfon (Dyacide) by persons not using at the optimum pH or GH OR NOT being aware of just how effective ...
Trichlorfon. CAS: 52-68-6 Formula: C4H8Cl3O4P. Weight: 257.43700. Synonyms: Bilarcil; Chlorophos; (2,2,2-Trichloro... ...
trichlorfon. mg/kg. 0.05. trifloxystrobin. sum of trifloxystrobin and its acid metabolite ((E,E)-methoxyimino-[2-[1-(3- ...
Would you like to know how much pesticides are in the food you eat? Zego is launching a kickstarter, sharing their pesticide data reports and challenging other brands to do the same thing.
TRICHLORFON 52-68-6 NFACJZMKEDPNKN-UHFFFAOYSA-N 0.5 0 #, 3 FENTHION 55-38-9 PNVJTZOFSHSLTO-UHFFFAOYSA-N 4.1 1 #, 4 CARBON ...
Antihelmintics - Trichlorfon.. *Herbicides - Tribufos (DEF), merphos.. What are organophosphate pesticides?. Organophosphate ...
Trichlorfon is a selective insecticide, targeting only cockroaches, crickets, silverfish, bedbugs, fleas, cattle grubs, flies, ... http://www.naturalpedia.com/trichlorfon-toxicity-side-effects-diseases-and-environmental-impacts.html ...
metrifonate / trichlorfon (Bilarcil ) => dichlorvos / 2,2-dichlorovinyl dimethyl phosphate (DDVP) *haloxon (Loxon ) ...
2). The food-lure contained a mixture of liquor, water, brown sugar, vinegar, and trichlorfon (Chen et al. 1989). From the food ...
Trichlorfon spray for snake mites (Ophionyssus natricis). Bulletin of the Association of Reptile and Amphibian Veterinarians 1( ...
Safe-Guard Paste 10% is approved for use concomitantly with an approved form of trichlorfon. Trichlorfon is approved for the ... Refer to label information for directions for use and cautions for trichlorfon.. For Beef and Dairy Cattle, Safe-Guard Paste 10 ...
Trichlorfon 6.2%. Target pests. Annual bluegrass weevils (larvae and adult), armyworms, chinch bugs, cutworms, sod webworms, ...
To control bots, trichlorfon may be administered concurrently. AMMO Rotational Wormer may be administered to sick, debilitated ...
Look for products that contain the active ingredients Chlorantraniliprole, Bifenthrin, Lambda-Cyhalothrin, and Trichlorfon. ...
Approved for concurrent use with an approved form of Trichlorfon (Boticide). Selection of the store only applies in the cart/ ...
  • Refer to label information for directions for use and cautions for trichlorfon. (horse.com)
  • When using PANACUR (fenbendazole) Paste 10% concomitantly with trichlorfon, refer to the manufacturer's labels for use and cautions for trichlorfon. (merck-animal-health-usa.com)
  • 1984. Genotoxic activity of dichlorvos, trichlorfon, and dichloroacetaldehyde. (cdc.gov)
  • Trichlorfon/metrifonate was banned in Argentina in 2018, noting that trichlorvon converts to dichlorvos by metabolism in plants, as well as by biodegradation of the soil. (wikipedia.org)
  • In this method, dichlorvos is created by dehydrochlorinating trichlorfon in aqueous alkali. (procurementresource.com)
  • Trichlorfon is an organophosphate insecticide and acaricide that is widely used in agriculture, horticulture, and public health sectors to control a broad range of insect pests. (sdnewswire.com)
  • Stringent Regulations: Trichlorfon is an organophosphate insecticide, and regulatory bodies often impose strict regulations on its production, use, and distribution due to its potential health and environmental risks. (sdnewswire.com)
  • Metrifonate (INN) or trichlorfon (USAN) is an irreversible organophosphate acetylcholinesterase inhibitor. (wikipedia.org)
  • Trichlorfon (Dylox) is an Organophosphate and degrades rapidly (approximately 99% of applied degraded in 2 hours) in alkaline pond water (pH 8.5) at room temperature. (americanaquariumproducts.com)
  • Carbofuran, Short-chain chlorinated paraffins, Tributyltin compounds and Trichlorfon were recently added to the blacklisted substances, described as most hazardous to human health and environment. (org.in)
  • Spraying trichlorfon or dimethoate 40% EC (dimethoate 40% emulsifiable concentrate, a systemic and contact insecticide and miticide) can control aphids and cabbage caterpillars, which exist at every growth stage. (ufl.edu)
  • Safe-Guard Paste 10% is approved for use concomitantly with an approved form of trichlorfon. (horse.com)
  • Resistance Development: Prolonged and extensive use of Trichlorfon can contribute to the development of resistance in target pests. (sdnewswire.com)
  • Trichlorfon is approved for the treatment of stomach bots (Gasterophilus spp. (horse.com)
  • To control bots, trichlorfon may be administered concurrently. (equineperformance.com.au)
  • Health and Safety Risks: Trichlorfon is known to be toxic to humans if not handled properly. (sdnewswire.com)
  • Trichlorfon is highly toxic to invertebrates. (americanaquariumproducts.com)
  • Although I will admit the evidence at this point is anecdotal, but since Trichlorfon is highly toxic to snails, the use of this treatment to kill snails (or in their presence) can rapidly decrease pH (especially in tanks in low KH) as snails rapidly die off (which can release other toxins). (americanaquariumproducts.com)
  • But Trichlorfon remains stable in the same pond water held under acidic (pH 5.0) conditions for 2 hours. (americanaquariumproducts.com)
  • An important fact may be "at play" in that Trichlorfon is more stable in lower pH water with lower calcium levels, thus retaining its toxicity for a longer period of time which the often high organic decomposition found in tanks with high snail populations may allow a "snow ball" effect of dying snails, increasingly lower pH, and increasing toxicity of Trichlorfon which may result in the death of fish as well. (americanaquariumproducts.com)
  • Trichlorfon is a colourless crystalline powder that is stable at room temperature. (unep.org)
  • Dipterex (Trichlorfon) Market also known as the Trichlorfon market, refers to the global industry involved in the production, distribution, and sale of the chemical compound Trichlorfon, which is commonly marketed under the trade name Dipterex. (sdnewswire.com)
  • Trichlorfon is organophosphorous pesticide and among the most commonly used products to treat fish parasites in aquaculture. (medkoo.com)
  • Trichlorfon : health and safety guide. (who.int)
  • There is no recommended dosage (other than Freshwater fish acute toxicity= 1.6-180 ppm), refer to manufacturers directions for all products containing Trichlorfon. (americanaquariumproducts.com)
  • Look for products that contain the active ingredients Chlorantraniliprole, Bifenthrin, Lambda-Cyhalothrin, and Trichlorfon. (moneypit.com)
  • It is also manufactured by heating a chemical called trichlorfon. (cdc.gov)
  • Trichlorfon is best used in water with mid pH readings of about 7.2 and a GH of about 7-14dGH for optimum & safest results. (americanaquariumproducts.com)
  • The organophosphate Trichlorfon (Dipterex, Masoten, Metrifonate, Dylox, Negavon are all the same thing) is used quite frequently in koi keeping because it is very effective against various flukes (both gill and body fluke), fish lice, anchor worm, Ergasilus. (ecotao.co.za)
  • The larvae can be targeted with systemic insecticides (diamides, neonicotinoids) when small and with systemic (see above) and non-systemic insecticides (spinosad, indoxacarb and the organophosphate trichlorfon [Dylox, Bayer]) when feeding externally (1). (gcmonline.com)
  • In all of the container tests, insecticide treatments and rates provided 100% larval control, with the exception of dinotefuran and bifenthrin + trichlorfon, which each had one low and one high rate that exceeded larval thresholds for the DJHP. (usda.gov)
  • University of Connecticut researchers recommend curing white grubs from zoysia grass with an insecticide containing the active ingredient trichlorfon. (gardenguides.com)
  • Trichlorfon is a widely used organophosphorus insecticide. (bvsalud.org)
  • In the United States, trichlorfon/metrifonate may only be used on nonfood and nonfeed sites. (wikipedia.org)
  • Trichlorfon/metrifonate was banned in the EU in 2008 (Regulation (EC) 689/2008) and in Brazil in 2010. (wikipedia.org)
  • Trichlorfon/metrifonate was banned in New Zealand in 2011. (wikipedia.org)
  • Trichlorfon/metrifonate was banned in India from 2020. (wikipedia.org)
  • 3-Month Evaluation of the Toxicity (C54831B) of Trichlorfon (52-68-6) in F344 Rats Exposed via Dosed Feed. (nih.gov)
  • Genetic Toxicity Evaluation of Trichlorfon in Salmonella/E.coli Mutagenicity Test or Ames Test. (nih.gov)
  • Pesticides and insecticides such as trichlorfon, dimilin and Diazinon can impact wildlife such as bees and other insects. (ecotao.co.za)
  • Certains des principaux résultats de la Conférence comprennent l'inscription de quatre nouveaux produits chimiques dans l'Annexe III de la Convention, à savoir le carbofuran et le trichlorfon comme pesticides, et les paraffines chlorées à chaîne courte et les composés de tributylétain en tant que produits chimiques industriels et la décision d'un travail intersessions sur l'amélioration de l'efficacité de la Convention. (pic.int)
  • Pesticides such as acephate , bifenthrin, carbaryl, imidacloprid and trichlorfon do a good job of killing lawn pests but also have adverse effects on nontargeted insects and birds. (dirtdoctor.com)
  • Berdasarkan laporan penelitian terbaru kami mengenai industri Dipterex (Trichlorfon) di seluruh dunia, terlihat jelas bahwa sektor ini sedang mengalami ekspansi global yang signifikan. (kompasjatim.com)
  • 2. Tinjauan Pustaka: Pada segmen ini disajikan gambaran menyeluruh tentang penelitian-penelitian terdahulu terkait Dipterex (Trichlorfon), yang mencakup teori-teori, model-model, dan temuan-temuan yang relevan dari penelitian-penelitian terkini. (kompasjatim.com)
  • 7. Referensi: Pada kategori ini disajikan daftar lengkap sumber-sumber yang digunakan dalam laporan penelitian Dipterex (Trichlorfon). (kompasjatim.com)
  • Temukan faktor-faktor pendorong pertumbuhan pasar Dipterex (Trichlorfon), dengan fokus khusus pada wilayah dimana ekspansi sangat menonjol. (kompasjatim.com)
  • 4. Menawarkan wawasan berharga mengenai riset pasar Dipterex (Trichlorfon), yang menggabungkan analisis SWOT dan tren regional. (kompasjatim.com)
  • Fluke Tabs by Aquarium (USA) - Trichlorfon and mebendazole. (fishlore.com)
  • The flowable formulation of bifenthrin (Talstar® Nursery F) alone or in combination with imidacloprid or trichlorfon also exceeded industry standards at the lowest rates tested. (usda.gov)
  • All spring B&B tests met industry standards with the exception of one bifenthrin + trichlorfon treatment at the lowest rate tested. (usda.gov)
  • The effect of organophosphorous pesticide trichlorfon on ChE activity was investigated in vitro in both species as well as in the gills of mussels Mytilus galloprovincialis. (irb.hr)
  • According to the US Environmental Protection Agency trichlorfon has been used on golf course turf, home lawns, non-food contact areas of food and meat processing plants, ornamental shrubs and plants, and ornamental and baitfish ponds. (wikipedia.org)
  • 17. Effects of trichlorfon on malondialdehyde and antioxidant system in human erythrocytes. (nih.gov)
  • In this study, we explored the effects of trichlorfon on the steroidogenesis and the expression of genes in androgen biosynthetic and metabolic cascades in immature Leydig cells isolated from pubertal male rats. (bvsalud.org)
  • Trichlorfon significantly inhibited total androgen output at 50 µM, which was partially reversed by 400 µg/ml vitamin E, which alone had no effects on androgen output. (bvsalud.org)
  • Prescription 2: TRICHLORFON 0.2% ~ 0.3% solution nasal drops, 3 times a day for 2 days. (medgmp.cn)
  • An overview of Genetic Toxicology Micronucleus Mice study conclusions related to Trichlorfon (52-68-6). (nih.gov)
  • The treatments were kaolin (Suround WP), trichlorfon baitspray as a positive control (Trichlorfon + protein hydrolysate (Nulure®) and unsprayed control. (iobc-wprs.org)