A chronic inflammatory process that affects the AORTA and its primary branches, such as the brachiocephalic artery (BRACHIOCEPHALIC TRUNK) and CAROTID ARTERIES. It results in progressive arterial stenosis, occlusion, and aneurysm formation. The pulse in the arm is hard to detect. Patients with aortitis syndrome often exhibit retinopathy.
A specific HLA-B surface antigen subtype. Members of this subtype contain alpha chains that are encoded by the HLA-B*52 allele family.
INFLAMMATION of any ARTERIES.
A systemic autoimmune disorder that typically affects medium and large ARTERIES, usually leading to occlusive granulomatous vasculitis with transmural infiltrate containing multinucleated GIANT CELLS. The TEMPORAL ARTERY is commonly involved. This disorder appears primarily in people over the age of 50. Symptoms include FEVER; FATIGUE; HEADACHE; visual impairment; pain in the jaw and tongue; and aggravation of pain by cold temperatures. (From Adams et al., Principles of Neurology, 6th ed)
Inflammation of the wall of the AORTA.
The type species of the genus ARTERIVIRUS and the etiologic agent of an important equine respiratory disease causing abortion, pneumonia, or other infections.
Artery arising from the brachiocephalic trunk on the right side and from the arch of the aorta on the left side. It distributes to the neck, thoracic wall, spinal cord, brain, meninges, and upper limb.
Radiographic visualization of the aorta and its branches by injection of contrast media, using percutaneous puncture or catheterization procedures.
Pathological processes that affect voice production, usually involving VOCAL CORDS and the LARYNGEAL MUCOSA. Voice disorders can be caused by organic (anatomical), or functional (emotional or psychological) factors leading to DYSPHONIA; APHONIA; and defects in VOICE QUALITY, loudness, and pitch.
Arteries arising from the external carotid or the maxillary artery and distributing to the temporal region.
Radiography of blood vessels after injection of a contrast medium.
Non-invasive method of vascular imaging and determination of internal anatomy without injection of contrast media or radiation exposure. The technique is used especially in CEREBRAL ANGIOGRAPHY as well as for studies of other vascular structures.
The period of recovery following an illness.
A syndrome in the elderly characterized by proximal joint and muscle pain, high erythrocyte sedimentation rate, and a self-limiting course. Pain is usually accompanied by evidence of an inflammatory reaction. Women are affected twice as commonly as men and Caucasians more frequently than other groups. The condition is frequently associated with GIANT CELL ARTERITIS and some theories pose the possibility that the two diseases arise from a single etiology or even that they are the same entity.
Pathological condition characterized by the backflow of blood from the ASCENDING AORTA back into the LEFT VENTRICLE, leading to regurgitation. It is caused by diseases of the AORTIC VALVE or its surrounding tissue (aortic root).
A group of CORTICOSTEROIDS that affect carbohydrate metabolism (GLUCONEOGENESIS, liver glycogen deposition, elevation of BLOOD SUGAR), inhibit ADRENOCORTICOTROPIC HORMONE secretion, and possess pronounced anti-inflammatory activity. They also play a role in fat and protein metabolism, maintenance of arterial blood pressure, alteration of the connective tissue response to injury, reduction in the number of circulating lymphocytes, and functioning of the central nervous system.
Tomography using x-ray transmission and a computer algorithm to reconstruct the image.

Endovascular stent graft repair of aortopulmonary fistula. (1/283)

Two patients who had aortopulmonary fistula of postoperative origin with hemoptysis underwent successful repair by means of an endovascular stent graft procedure. One patient had undergone repeated thoracotomies two times, and the other one time to repair anastomotic aneurysms of the descending aorta after surgery for Takayasu's arteritis. A self-expanding stainless steel stent covered with a Dacron graft was inserted into the lesion through the external iliac or femoral artery. The patients recovered well, with no signs of infection or recurrent hemoptysis 8 months after the procedure. Endovascular stent grafting may be a therapeutic option for treating patients with aortopulmonary fistula.  (+info)

Intimal tear without hematoma: an important variant of aortic dissection that can elude current imaging techniques. (2/283)

BACKGROUND: The modern imaging techniques of transesophageal echocardiography, CT, and MRI are reported to have up to 100% sensitivity in detecting the classic class of aortic dissection; however, anecdotal reports of patient deaths from a missed diagnosis of subtle classes of variants are increasingly being noted. METHODS AND RESULTS: In a series of 181 consecutive patients who had ascending or aortic arch repairs, 9 patients (5%) had subtle aortic dissection not diagnosed preoperatively. All preoperative studies in patients with missed aortic dissection were reviewed in detail. All 9 patients (2 with Marfan syndrome, 1 with Takayasu's disease) with undiagnosed aortic dissection had undergone >/=3 imaging techniques, with the finding of ascending aortic dilatation (4.7 to 9 cm) in all 9 and significant aortic valve regurgitation in 7. In 6 patients, an eccentric ascending aortic bulge was present but not diagnostic of aortic dissection on aortography. At operation, aortic dissection tears were limited in extent and involved the intima without extensive undermining of the intima or an intimal "flap." Eight had composite valve grafts inserted, and all survived. Of the larger series of 181 patients, 98% (179 of 181) were 30-day survivors. CONCLUSIONS: In patients with suspected aortic dissection not proven by modern noninvasive imaging techniques, further study should be performed, including multiple views of the ascending aorta by aortography. If patients have an ascending aneurysm, particularly if eccentric on aortography and associated with aortic valve regurgitation, an urgent surgical repair should be considered, with excellent results expected.  (+info)

Interleukin-6 and RANTES in Takayasu arteritis: a guide for therapeutic decisions? (3/283)

BACKGROUND: In patients with Takayasu arteritis, circulating lymphocytes are activated, and histological findings indicate that cell-mediated immunity plays an important role in the pathogenetic sequence leading to vascular lesions. METHODS AND RESULTS: To delineate the profile of inflammatory and chemoattractant cytokines involved in T-cell activation in Takayasu arteritis, we measured by ELISA serum levels of interleukin (IL)-6, IL-1beta, and RANTES in 18 patients. Subsequently, we wanted to establish whether any of these molecules could be used as a marker to monitor the clinical course of the disease and to predict disease exacerbations. We found that all patients with Takayasu arteritis studied during an active phase of the disease have increased serum concentration of IL-6 compared with healthy control subjects (P<0.01). Enhanced IL-6 serum levels paralleled disease activity to the extent that its serum concentrations were comparable to those of control subjects when patients were studied in remission. RANTES concentrations were also higher than normal in the serum of all patients with Takayasu arteritis (P<0.01) studied during an active phase of the disease. RANTES serum levels tended to normalize in remission, but values remained higher than those of control subjects (P<0.05). In contrast, serum concentrations of IL-1beta were below the detection limit of ELISA in both healthy subjects and all patients with Takayasu arteritis. A positive correlation was found between either IL-6 (rho=0.705, P<0.01) or RANTES (rho=0.607, P<0.05) serum level and disease activity. CONCLUSIONS: The close correlation of serum IL-6 and RANTES levels with disease activity suggests that these cytokines contribute to vasculitic lesions in Takayasu arteritis and raises the possibility that their monitoring in serum helps clinicians find adequate treatment adjustments in individual patients.  (+info)

Monoclonal anti-endothelial cell antibodies from a patient with Takayasu arteritis activate endothelial cells from large vessels. (4/283)

OBJECTIVE: To create monoclonal anti-endothelial cell antibodies (mAECA) from a patient with Takayasu arteritis to evaluate their ability to activate human umbilical vein endothelial cells (HUVEC), and to characterize the mechanism of EC activation. METHODS: A panel of mAECA was generated from peripheral blood lymphocytes of a patient with Takayasu arteritis, using Epstein-Barr virus transformation. Activity against macrovascular EC (HUVEC) and microvascular EC (human bone marrow EC immortalized by SV40) antigens was detected by enzyme-linked immunosorbent assay. Inhibition studies were used to select the monoclonal antibodies (mAECA) which share the same EC epitope binding specificity as the total IgG-AECA from the Takayasu arteritis patient. The binding of the mAECA to human aortic EC was studied by immunohistochemistry. The secretion levels of interleukin-6 (IL-6) and von Willebrand factor (vWF) were determined, to serve as markers for EC activation. The activated EC were examined for the adherence of a monocytic cell line (U937), as well as for expression of vascular cell adhesion molecule 1, intercellular adhesion molecule 1, and E-selectin. In addition, nuclear extracts of the mAECA-treated EC were analyzed for the induction of translocation of nuclear factor kappaB (NF-kappaB), using a specific NF-kappaB oligoprobe in an electrophoretic mobility shift assay. RESULTS: Six mAECA were selected, the mixture of which produced 100% inhibition of binding of the original IgG (from the patient with Takayasu arteritis) to HUVEC. All mAECA possessed high activity against macrovascular EC, but none had significant antimicrovascular EC activity. The mAECA, but not normal human IgG, had anti-human aortic EC activity. Four of the 6 mAECA activated EC, manifested by increased IL-6 and vWF secretion. The 4 mAECA induced EC expression of adhesion molecules and increased adhesion of U937 monocytic cells to EC. In addition, these mAECA stimulated the nuclear translocation of the NF-kappaB transcription factor. CONCLUSION: Our findings suggest that AECA may directly stimulate EC in Takayasu arteritis through elevation of adhesion molecule expression associated with NF-kappaB activation and adhesion of monocytes, and may therefore play a pathogenic role in the development of the vasculopathy in Takayasu arteritis.  (+info)

Cryopreserved aortic homograft replacement in a patient with Takayasu's arteritis. (5/283)

A patient with severe long-standing Takayasu's arteritis underwent successful replacement of the aortic root and ascending aorta with a cryopreserved aortic homograft. Her postoperative course was uneventful and echocardiography demonstrated evidence of neither aortic regurgitation nor graft detachment more than 2 years after the operation. Magnetic resonance image demonstrated no signs of graft enlargement.  (+info)

The acute diagnosis of Takayasu's arteritis based on helical CT angiography of the chest and neck in the emergency room. (6/283)

Recently, a young woman presented acutely with a left hemispheric stroke and differing blood pressures in the arms as her initial manifestation of Takayasu's arteritis. Helical CT angiography, performed to rule out aortic dissection, revealed a thickened wall of the aortic arch with stenoses and occlusions of the great vessels, suggesting the diagnosis. The sequence of imaging studies and findings in this unusually catastrophic presentation of a typically insidious disease are highlighted.  (+info)

Presence of antinucleosome autoantibodies in a restricted set of connective tissue diseases: antinucleosome antibodies of the IgG3 subclass are markers of renal pathogenicity in systemic lupus erythematosus. (7/283)

OBJECTIVE: To study the frequency and disease specificity of antinucleosome antibody reactivity in diverse connective tissue diseases (CTD), and to determine factors, such as antibody subclass, that may influence the pathogenicity of these antibodies in relation to disease activity. METHODS: IgG and IgM antinucleosome activities on nucleosome core particles from 496 patients with 13 different CTD and 100 patients with hepatitis C were measured by enzyme-linked immunosorbent assay (ELISA). Of the patients with CTD, 120 had systemic lupus erythematosus (SLE), 37 had scleroderma (systemic sclerosis; SSc), 20 had mixed connective tissue disease (MCTD), and 319 had other CTD, including Sjogren's syndrome, inflammatory myopathy, rheumatoid arthritis, primary antiphospholipid syndrome, Wegener's granulomatosis, Takayasu arteritis, giant cell arteritis, relapsing polychondritis, Behcet's syndrome, and sarcoidosis. Antinucleosome-positive sera were further analyzed, by isotype-specific ELISA, for antinucleosome and anti-double-stranded DNA (anti-dsDNA) IgG subclasses. RESULTS: SLE, SSc, and MCTD were the only 3 CTD in which antinucleosome IgG were detected (71.7%, 45.9%, and 45.0% of patients, respectively). Antinucleosomes of the IgG3 subclass were present at high levels in patients with active SLE and were virtually absent in those with SSc, MCTD, or inactive SLE, and their levels showed a positive correlation with SLE disease activity. Of note, an increase in levels of antinucleosome of the IgG3 isotype was observed during SLE flares, and this increase was found to be closely associated with active nephritis. Levels of antinucleosome of the IgG1 subclass showed a trend toward an inverse correlation with SLE disease activity. No significant fluctuation in the anti-dsDNA isotype profile was observed in relation to SLE severity or clinical signs. CONCLUSION: Our data suggest that IgG antinucleosome is a new marker that may help in the differential diagnosis of CTD; antinucleosome of the IgG3 isotype might constitute a selective biologic marker of active SLE, in particular, of lupus nephritis.  (+info)

Takayasu's arteritis in a 69 year-old woman. (8/283)

Takayasu's arteritis and temporal arteritis share many clinical and pathological features. The most discriminatory feature between the two diseases is the age at onset; the mean age at onset of the disease was reported as being 26 years for Takayasu's arteritis and 69 years for temporal arteritis. Here we report a 69-year-old woman who presented with a weak right radial artery pulse. The ethnic background and the presence of vascular insufficiency of the right upper extremity and the absence of clinical signs such as shoulder stiffness and tender scalp indicate that her diagnosis is Takayasu's arteritis. It must be emphasized that the two conditions could be differentiated based on the clinical findings even in a patient as old as 69 years old.  (+info)

Takayasu arteritis is a rare inflammatory disease that affects the large blood vessels in the body, most commonly the aorta and its main branches. It's also known as pulseless disease or aortic arch syndrome. The condition primarily affects young to middle-aged women, although it can occur in anyone at any age.

The inflammation caused by Takayasu arteritis can lead to narrowing, thickening, and weakening of the affected blood vessels' walls, which can result in reduced blood flow to various organs and tissues. This can cause a variety of symptoms depending on the severity and location of the vessel involvement.

Common symptoms include:

* Weak or absent pulses in the arms and/or legs
* High blood pressure (hypertension)
* Dizziness, lightheadedness, or fainting spells due to reduced blood flow to the brain
* Headaches
* Visual disturbances
* Fatigue
* Weight loss
* Night sweats
* Fever

Diagnosis of Takayasu arteritis typically involves a combination of medical history, physical examination, laboratory tests, and imaging studies. Treatment usually includes corticosteroids or other immunosuppressive medications to control inflammation and maintain remission. Regular follow-up with a healthcare provider is essential to monitor disease activity and adjust treatment as necessary.

HLA-B52 is a specific antigen of the human leukocyte antigen (HLA) system, which is located on chromosome 6 and plays an important role in the immune system. The HLA system helps the body to recognize and distinguish its own cells from foreign substances such as viruses and bacteria.

HLA-B52 is a type of HLA-B antigen, which is a group of proteins found on the surface of cells that help the immune system identify and destroy infected or damaged cells. The HLA-B52 antigen is most commonly found in individuals of Asian descent, particularly those from Japan and Korea.

It's important to note that the presence or absence of the HLA-B52 antigen does not necessarily indicate the presence or absence of a specific disease. However, certain genetic associations have been reported between HLA-B52 and some diseases such as Behçet's disease, which is a chronic inflammatory disorder that causes symptoms such as mouth sores, genital sores, eye inflammation, and skin lesions.

Arteritis is a medical condition characterized by inflammation of the arteries. It is also known as vasculitis of the arteries. The inflammation can cause the walls of the arteries to thicken and narrow, reducing blood flow to affected organs or tissues. There are several types of arteritis, including:

1. Giant cell arteritis (GCA): Also known as temporal arteritis, it is a condition that mainly affects the large and medium-sized arteries in the head and neck. The inflammation can cause headaches, jaw pain, scalp tenderness, and vision problems.
2. Takayasu's arteritis: This type of arteritis affects the aorta and its major branches, mainly affecting young women. Symptoms include fever, weight loss, fatigue, and decreased pulse in the arms or legs.
3. Polyarteritis nodosa (PAN): PAN is a rare systemic vasculitis that can affect medium-sized arteries throughout the body. It can cause a wide range of symptoms, including fever, rash, abdominal pain, and muscle weakness.
4. Kawasaki disease: This is a type of arteritis that mainly affects children under the age of 5. It causes inflammation in the blood vessels throughout the body, leading to fever, rash, swollen lymph nodes, and red eyes.

The exact cause of arteritis is not fully understood, but it is believed to be an autoimmune disorder, where the body's immune system mistakenly attacks its own tissues. Treatment for arteritis typically involves medications to reduce inflammation and suppress the immune system.

Giant Cell Arteritis (GCA), also known as Temporal Arteritis, is a chronic inflammatory disease affecting large and medium-sized arteries, most commonly the temporal artery. It primarily occurs in people over 50 years old. The condition is characterized by the infiltration of the artery walls with immune cells, leading to inflammation, swelling, and damage. This can restrict blood flow, causing various symptoms.

The key feature of GCA is the presence of multinucleated giant cells, which are large collections of fused immune cells, in the affected artery walls. These cells are a hallmark of this condition when viewed under a microscope.

Common symptoms include new onset of severe headaches, scalp tenderness, jaw pain while chewing (called jaw claudication), vision problems, and systemic symptoms such as fever, fatigue, and weight loss. If left untreated, GCA can lead to serious complications like blindness or stroke. Treatment typically involves high-dose corticosteroids to reduce inflammation and prevent further damage.

Aortitis is a medical condition characterized by inflammation of the aorta, which is the largest artery in the body that carries oxygenated blood from the heart to the rest of the body. The inflammation can cause damage to the aortic wall, leading to weakening, bulging (aneurysm), or tearing (dissection) of the aorta. Aortitis can be caused by various conditions, including infections, autoimmune diseases, and certain medications. It is essential to diagnose and treat aortitis promptly to prevent serious complications.

I'm sorry for any confusion, but there seems to be a mistake in your question. "Arteritis Virus, Equine" is not a recognized medical term or virus in humans or animals. There is a condition called "Equine Viral Arteritis (EVA)," which is a viral disease that affects horses and other equine species. However, it does not affect humans.

Equine Viral Arteritis (EVA) is caused by the Equine Arteritis Virus (EAV). This virus primarily affects the respiratory system and can cause symptoms such as fever, lethargy, loss of appetite, and a runny nose in infected horses. In some cases, it may also lead to inflammation of the lining of blood vessels (vasculitis), which can result in abortion in pregnant mares or infertility in stallions.

It's essential to maintain proper biosecurity measures when dealing with horses, especially those that have been exposed to EVA, to prevent its spread and protect the health of other equine populations.

The subclavian artery is a major blood vessel that supplies the upper limb and important structures in the neck and head. It arises from the brachiocephalic trunk (in the case of the right subclavian artery) or directly from the aortic arch (in the case of the left subclavian artery).

The subclavian artery has several branches, including:

1. The vertebral artery, which supplies blood to the brainstem and cerebellum.
2. The internal thoracic artery (also known as the mammary artery), which supplies blood to the chest wall, breast, and anterior mediastinum.
3. The thyrocervical trunk, which gives rise to several branches that supply the neck, including the inferior thyroid artery, the suprascapular artery, and the transverse cervical artery.
4. The costocervical trunk, which supplies blood to the neck and upper back, including the posterior chest wall and the lower neck muscles.

The subclavian artery is a critical vessel in maintaining adequate blood flow to the upper limb, and any blockage or damage to this vessel can lead to significant morbidity, including arm pain, numbness, weakness, or even loss of function.

Aortography is a medical procedure that involves taking X-ray images of the aorta, which is the largest blood vessel in the body. The procedure is usually performed to diagnose or assess various conditions related to the aorta, such as aneurysms, dissections, or blockages.

To perform an aortography, a contrast dye is injected into the aorta through a catheter that is inserted into an artery, typically in the leg or arm. The contrast dye makes the aorta visible on X-ray images, allowing doctors to see its structure and any abnormalities that may be present.

The procedure is usually performed in a hospital or outpatient setting and may require sedation or anesthesia. While aortography can provide valuable diagnostic information, it also carries some risks, such as allergic reactions to the contrast dye, damage to blood vessels, or infection. Therefore, it is typically reserved for situations where other diagnostic tests have been inconclusive or where more invasive treatment may be required.

Voice disorders are conditions that affect the quality, pitch, or volume of a person's voice. These disorders can result from damage to or abnormalities in the vocal cords, which are the small bands of muscle located in the larynx (voice box) that vibrate to produce sound.

There are several types of voice disorders, including:

1. Vocal cord dysfunction: This occurs when the vocal cords do not open and close properly, resulting in a weak or breathy voice.
2. Vocal cord nodules: These are small growths that form on the vocal cords as a result of excessive use or misuse of the voice, such as from shouting or singing too loudly.
3. Vocal cord polyps: These are similar to nodules but are usually larger and can cause more significant changes in the voice.
4. Laryngitis: This is an inflammation of the vocal cords that can result from a viral infection, overuse, or exposure to irritants such as smoke.
5. Muscle tension dysphonia: This occurs when the muscles around the larynx become tense and constricted, leading to voice changes.
6. Paradoxical vocal fold movement: This is a condition in which the vocal cords close when they should be open, causing breathing difficulties and a weak or breathy voice.
7. Spasmodic dysphonia: This is a neurological disorder that causes involuntary spasms of the vocal cords, resulting in voice breaks and difficulty speaking.

Voice disorders can cause significant impairment in communication, social interactions, and quality of life. Treatment may include voice therapy, medication, or surgery, depending on the underlying cause of the disorder.

Temporal arteries are the paired set of arteries that run along the temples on either side of the head. They are branches of the external carotid artery and play a crucial role in supplying oxygenated blood to the scalp and surrounding muscles. One of the most common conditions associated with temporal arteries is Temporal Arteritis (also known as Giant Cell Arteritis), which is an inflammation of these arteries that can lead to serious complications like vision loss if not promptly diagnosed and treated.

Angiography is a medical procedure in which an x-ray image is taken to visualize the internal structure of blood vessels, arteries, or veins. This is done by injecting a radiopaque contrast agent (dye) into the blood vessel using a thin, flexible catheter. The dye makes the blood vessels visible on an x-ray image, allowing doctors to diagnose and treat various medical conditions such as blockages, narrowing, or malformations of the blood vessels.

There are several types of angiography, including:

* Cardiac angiography (also called coronary angiography) - used to examine the blood vessels of the heart
* Cerebral angiography - used to examine the blood vessels of the brain
* Peripheral angiography - used to examine the blood vessels in the limbs or other parts of the body.

Angiography is typically performed by a radiologist, cardiologist, or vascular surgeon in a hospital setting. It can help diagnose conditions such as coronary artery disease, aneurysms, and peripheral arterial disease, among others.

Magnetic Resonance Angiography (MRA) is a non-invasive medical imaging technique that uses magnetic fields and radio waves to create detailed images of the blood vessels or arteries within the body. It is a type of Magnetic Resonance Imaging (MRI) that focuses specifically on the circulatory system.

MRA can be used to diagnose and evaluate various conditions related to the blood vessels, such as aneurysms, stenosis (narrowing of the vessel), or the presence of plaques or tumors. It can also be used to plan for surgeries or other treatments related to the vascular system. The procedure does not use radiation and is generally considered safe, although people with certain implants like pacemakers may not be able to have an MRA due to safety concerns.

Convalescence is the period of recovery following a serious illness, injury, or medical treatment. During this time, the body gradually returns to its normal state of health and functioning. The length and intensity of the convalescent period can vary widely depending on the individual and the severity of the condition that required treatment.

During convalescence, it is important for individuals to take care of themselves and allow their bodies to heal properly. This may involve getting plenty of rest, eating a healthy diet, engaging in gentle exercise or physical therapy as recommended by a healthcare provider, and avoiding strenuous activities or stressors that could hinder recovery.

Convalescence is an essential part of the healing process, and it is important to allow oneself enough time to fully recover before returning to normal activities. Rushing the convalescent period can lead to setbacks, complications, or a prolonged recovery time. By taking the time to focus on self-care and healing during convalescence, individuals can help ensure a full and speedy recovery.

Polymyalgia Rheumatica (PMR) is a geriatric rheumatic disease characterized by widespread musculoskeletal pain and stiffness, particularly affecting the neck, shoulders, hips, and thighs. It is often accompanied by symptoms such as fatigue, weakness, loss of appetite, and low-grade fever. The onset of PMR can be sudden or gradual, and it tends to affect individuals over 50 years of age, more commonly women than men.

The exact cause of Polymyalgia Rheumatica remains unknown; however, it is believed to involve an autoimmune response leading to inflammation in the affected areas. Diagnosis typically involves a combination of clinical evaluation, laboratory tests (such as elevated erythrocyte sedimentation rate or C-reactive protein), and sometimes imaging studies. Treatment usually includes corticosteroids to reduce inflammation and manage symptoms, along with monitoring for potential side effects from long-term steroid use. In many cases, PMR can be successfully managed with appropriate treatment, allowing individuals to return to their normal activities.

Aortic valve insufficiency, also known as aortic regurgitation or aortic incompetence, is a cardiac condition in which the aortic valve does not close properly during the contraction phase of the heart cycle. This allows blood to flow back into the left ventricle from the aorta, instead of being pumped out to the rest of the body. As a result, the left ventricle must work harder to maintain adequate cardiac output, which can lead to left ventricular enlargement and heart failure over time if left untreated.

The aortic valve is a trileaflet valve that lies between the left ventricle and the aorta. During systole (the contraction phase of the heart cycle), the aortic valve opens to allow blood to be pumped out of the left ventricle into the aorta and then distributed to the rest of the body. During diastole (the relaxation phase of the heart cycle), the aortic valve closes to prevent blood from flowing back into the left ventricle.

Aortic valve insufficiency can be caused by various conditions, including congenital heart defects, infective endocarditis, rheumatic heart disease, Marfan syndrome, and trauma. Symptoms of aortic valve insufficiency may include shortness of breath, fatigue, chest pain, palpitations, and edema (swelling). Diagnosis is typically made through physical examination, echocardiography, and other imaging studies. Treatment options depend on the severity of the condition and may include medication, surgery to repair or replace the aortic valve, or a combination of both.

Glucocorticoids are a class of steroid hormones that are naturally produced in the adrenal gland, or can be synthetically manufactured. They play an essential role in the metabolism of carbohydrates, proteins, and fats, and have significant anti-inflammatory effects. Glucocorticoids suppress immune responses and inflammation by inhibiting the release of inflammatory mediators from various cells, such as mast cells, eosinophils, and lymphocytes. They are frequently used in medical treatment for a wide range of conditions, including allergies, asthma, rheumatoid arthritis, dermatological disorders, and certain cancers. Prolonged use or high doses of glucocorticoids can lead to several side effects, such as weight gain, mood changes, osteoporosis, and increased susceptibility to infections.

X-ray computed tomography (CT or CAT scan) is a medical imaging method that uses computer-processed combinations of many X-ray images taken from different angles to produce cross-sectional (tomographic) images (virtual "slices") of the body. These cross-sectional images can then be used to display detailed internal views of organs, bones, and soft tissues in the body.

The term "computed tomography" is used instead of "CT scan" or "CAT scan" because the machines take a series of X-ray measurements from different angles around the body and then use a computer to process these data to create detailed images of internal structures within the body.

CT scanning is a noninvasive, painless medical test that helps physicians diagnose and treat medical conditions. CT imaging provides detailed information about many types of tissue including lung, bone, soft tissue and blood vessels. CT examinations can be performed on every part of the body for a variety of reasons including diagnosis, surgical planning, and monitoring of therapeutic responses.

In computed tomography (CT), an X-ray source and detector rotate around the patient, measuring the X-ray attenuation at many different angles. A computer uses this data to construct a cross-sectional image by the process of reconstruction. This technique is called "tomography". The term "computed" refers to the use of a computer to reconstruct the images.

CT has become an important tool in medical imaging and diagnosis, allowing radiologists and other physicians to view detailed internal images of the body. It can help identify many different medical conditions including cancer, heart disease, lung nodules, liver tumors, and internal injuries from trauma. CT is also commonly used for guiding biopsies and other minimally invasive procedures.

In summary, X-ray computed tomography (CT or CAT scan) is a medical imaging technique that uses computer-processed combinations of many X-ray images taken from different angles to produce cross-sectional images of the body. It provides detailed internal views of organs, bones, and soft tissues in the body, allowing physicians to diagnose and treat medical conditions.

For example, Takaysus arteritis has an age of onset of 60 years. Takayasu arteritis is not associated with ANCA, rheumatoid ... Takayasus arteritis is similar to other forms of vasculitis, including giant cell arteritis which typically affects older ... The first case of Takayasus arteritis was described in 1908 by Japanese ophthalmologist Mikito Takayasu at the Annual Meeting ... Takayasus arteritis (TA), also known as aortic arch syndrome, nonspecific aortoarteritis, and pulseless disease, is a form of ...
Takayasus arteritis can be difficult to treat because the disease may remain active even if your symptoms improve. Its also ... If your primary care doctor suspects that you have Takayasus arteritis, he or she may refer you to one or more specialists ... Treatment of Takayasus arteritis focuses on controlling inflammation with medications and preventing further damage to your ... Understand your condition. Learn everything you can about Takayasus arteritis and its treatment. Know the possible side ...
Takayasu arteritis is a rare, systemic, inflammatory large-vessel vasculitis of unknown etiology that most commonly affects ... Takayasu arteritis. Aortogram of a 15-year-old girl with Takayasu arteritis. Note large aneurysms of descending aorta and ... Takayasu arteritis. MRI of thorax of 15-year-old girl with Takayasu arteritis. Note aneurysms of descending aorta. Image ... Takayasu arteritis. Coronal MRI of abdomen of 15-year-old girl with Takayasu arteritis. Note thickening and tortuosity of ...
Takayasus arteritis (pulseless disease) answers are found in the Diagnosaurus powered by Unbound Medicine. Available for ... Zeiger, Roni F.. "Takayasus Arteritis (pulseless Disease)." Diagnosaurus, 4th ed., McGraw-Hill Education, 2014. The Washington ... TY - ELEC T1 - Takayasus arteritis (pulseless disease) ID - 114126 A1 - Zeiger,Roni F, Y1 - 2014/12/01/ BT - Diagnosaurus UR ... Takayasus Arteritis (pulseless Disease) [Internet]. In: Diagnosaurus. McGraw-Hill Education; 2014. [cited 2023 December 07]. ...
An increased risk of malignancy was observed in patients with Takayasus arteritis compared to that in the general population ... All newly diagnosed patients with Takayasus arteritis were identified between January 2009 and December 2019. They were ... We identified 1449 newly diagnosed patients with Takayasus arteritis during the observational period (9196 person-years). A ... This study aimed to evaluate the relative risk of malignancy in patients with Takayasus arteritis compared to that in the ...
In this case, giant cell arteritis may be indistinguishable from Takayasu arteritis; however, initial treatment for both is ... Takayasu arteritis in Child. Print Images (5) Contributors: Michael Horwich MD, PhD, Nikki Levin MD, Susan Burgin MD, Paritosh ... Takayasu arteritis, also referred to as pulseless disease and aortic arch syndrome, is a rare chronic inflammatory vasculitis ... Pitfalls: On average, it takes 44 months from onset of symptoms to diagnose Takayasu arteritis. Because of its rarity and the ...
Focus on Takayasu Arteritis. Presented: August 30, 2016. Speaker: Peter C. Grayson, MD, MSc ...
Takayasus arteritis epidemiology and demographics ‎ (← links). *Takayasus arteritis natural history, complications and ... Pages that link to "Takayasus arteritis historical perspective". ← Takayasus arteritis historical perspective ... Retrieved from "https://www.wikidoc.org/index.php/Special:WhatLinksHere/Takayasu%27s_arteritis_historical_perspective" ... Takayasus arteritis x ray ‎ (← links). *Takayasus arteritis CT ‎ (← links). *Takayasus arteritis medical therapy ‎ (← links) ...
Surgical treatment of cerebral ischaemia caused by cervical arterial lesions due to Takayasus arteritis: preliminary results ... with surgical treatment of 49 cases of cerebral ischaemia caused by cervical arterial lesions due to Takayasus arteritis (TA ...
Takayasu Arteritis - Learn about the causes, symptoms, diagnosis & treatment from the Merck Manuals - Medical Consumer Version. ... Symptoms of Takayasu Arteritis Takayasu arteritis is a chronic disorder with symptoms that fluctuate in severity. ... Takayasu Arteritis (Pulseless Disease; Occlusive Thromboaortopathy; Aortic Arch Syndrome; Takayasus Arteritis). By ... Prognosis for Takayasu Arteritis For 20% of people, the disorder occurs once and does not return. For the rest, the disorder ...
Longterm Outcomes of Renal Artery Involvement in Takayasu Arteritis. Seokchan Hong, Byeongzu Ghang, Yong-Gil Kim, Chang-Keun ... Longterm Outcomes of Renal Artery Involvement in Takayasu Arteritis. Seokchan Hong, Byeongzu Ghang, Yong-Gil Kim, Chang-Keun ... A followup study of balloon angioplasty and de-novo stenting in Takayasu arteritis. Int J Cardiol 2000;75 Suppl 1:S147-52. ... Takayasus arteritis and its role in causing renal artery stenosis. Am J Med Sci 2013;346:314-8. ...
A person with Takayasus arteritis experiences arm or chest pain, hypertension causing high blood pressure, and they may ... Takayasus arteritis. This is a rare type of vasculitis where inflammation damages the aorta, which is the large artery ... Vasculitis is also called angiitis and arteritis. It causes alterations in the walls of blood vessels, which may include ...
Takayasus arteritis is an uncommon form of vasculitis. Inflammation damages large and medium-sized blood vessels. The vessels ... Prevention of Takayasus arteritis. As the precise etiology of Takayasu arteritis and causes of flare-ups in disease activity ... Causes of Takayasus arteritis. In Takayasus arteritis, the aorta and other major arteries, including those leading to the ... Takayasus arteritis Prevalence Takayasus arteritis is primarily a disease of adolescent girls and young women, who account ...
A whole body CT angiography was performed to further investigate a suspected Takayasu arteritis in 43-year old female patient. ... Takayasu arteritis (TA) was suspected and a Dual Energy (DE) whole body CT angiography (CTA) was performed for further ...
PG is associated with many systemic diseases, but association with Takayasus arteritis (TA) / pulseless disease, ... PYODERMA GANGRENOSUM SECONDARY TO TAKAYASUS ARTERITIS. Document. Metadata. Title. PYODERMA GANGRENOSUM SECONDARY TO TAKAYASUS ... PG is associated with many systemic diseases, but association with Takayasus arteritis (TA) / pulseless disease, which is ...
Percutaneous Transluminal Angioplasty for Brain Ischemia due to Takayasus Arteritis.. Hyun Jeong Kim, Chul Seung Lee, Seung ... PTA was performed in four consecutive patients (women, age range 33-38 years) with Takayasus arteritis (TA) with neurological ... of supra-aortic arteries in patients presenting with neurological manifestations caused by Takayasus arteritis.. MATERIALS AND ...
Takayasu Arteritis - Learn about the causes, symptoms, diagnosis & treatment from the MSD Manuals - Medical Consumer Version. ... Symptoms of Takayasu Arteritis Takayasu arteritis is a chronic disorder with symptoms that fluctuate in severity. ... Takayasu Arteritis (Pulseless Disease; Occlusive Thromboaortopathy; Aortic Arch Syndrome; Takayasus Arteritis). By ... Prognosis for Takayasu Arteritis For 20% of people, the disorder occurs once and does not return. For the rest, the disorder ...
Takayasus arteritis - Doctors and departments - Mayo Clinic. aneurysm surgery, Popliteal stenting, Transcarotid artery ...
Takayasu arteritis is a rare, chronic, idiopathic, granulomatous, inflammatory disease primarily involving large v ... Takayasu Arteritis-Evaluated by CT Angiography. Dr. Bhagvati Ukani [2] , Dr. Daksha Chhotala [2] , Dr. Abhishek [30] ... Abhishek, "Takayasu Arteritis-Evaluated by CT Angiography", International Journal of Science and Research (IJSR), Volume 12 ... Abstract: Takayasu arteritis is a rare, chronic, idiopathic, granulomatous, inflammatory disease primarily involving large ...
Isolated Thoracic Aortic Takayasu Arteritis Presenting as Presumed Mobile Aortic Thrombus. Aleem K. Mirza, Nishant Saran, ... Isolated Thoracic Aortic Takayasu Arteritis Presenting as Presumed Mobile Aortic Thrombus. / Mirza, Aleem K.; Saran, Nishant; ... Isolated Thoracic Aortic Takayasu Arteritis Presenting as Presumed Mobile Aortic Thrombus. In: Vascular and Endovascular ... Mirza AK, Saran N, Warrington KJ, Pochettino A, Shuja F. Isolated Thoracic Aortic Takayasu Arteritis Presenting as Presumed ...
Giant aortic aneurysm in a child with Takayasu arteritis - Volume 26 Issue 3 ... Letter to the Editor: Some thoughts concerning dealing with an aneurysmal disease in children with Takayasu arteritis: a rare ... Takayasus arteritis: a study of 104 Italian patients. Arthritis Rheum 2005; 53: 100-107.CrossRefGoogle ScholarPubMed ... Takayasu arteritis revisited: current diagnosis and treatment. Int J Cardiol 2013; 168: 3-10.CrossRefGoogle Scholar ...
She was treated with oral prednisolone 1 mg/kg and methotrexate 15 mg/week for active Takayasus arteritis. After a month of ... Bilateral carotid artery aneurysm presenting as pulsatile neck swelling: an unusual presentation of Takayasus arteritis. ...
Atypical Takayasu arteritis: A family with five affected siblings Irfan Jeeva, Jamal Sajid, [...] Osman Ali, David T. Bonthron ... Atypical Takayasu arteritis: A family with five affected siblings Irfan Jeeva, Jamal Sajid, Osman Ali, David T. Bonthron, ...
Takayasu arteritis. 3 (2%) of 180. Piette et al [21] Mesenteric panniculitis ...
Takayasu arteritis. In: Hochberg MC, Gravallese EM, Silman AJ, Smolen JS, Weinblatt ME, Weisman MH, eds. Rheumatology. 7th ed. ... An inflammatory disease called Takayasu syndrome may result in narrowing (stenosis) of the vessels of the aortic arch. This ...
Takayasus Arteritis. *Vasculitis. *Wegeners Granulomatosis. *Joint Drainage. *Joint Fluid Test. *Musculoskeletal Function ...
Takayasu arteritis; Wegener granulomatosis; familial Mediterranean fever; sarcoidosis, Lofgren syndrome ... immunologic and inflammatory disorders: acute rheumatic fever; autoimmune arteritis/vasculitis; Behçet syndrome; Churg-Strauss ... temporal arteritis; Raynaud disease/Raynaud syndrome; reactive arthritis, formerly Reiter disease, including Reiter arthritis; ...
Takayasu arteritis. 3 (2%) of 180. Piette et al [21] Mesenteric panniculitis ...

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