The flow of BLOOD through or around an organ or region of the body.
Small uniformly-sized spherical particles, of micrometer dimensions, frequently labeled with radioisotopes or various reagents acting as tags or markers.
A value equal to the total volume flow divided by the cross-sectional area of the vascular bed.
The volume of BLOOD passing through the HEART per unit of time. It is usually expressed as liters (volume) per minute so as not to be confused with STROKE VOLUME (volume per beat).
The circulation of blood through the BLOOD VESSELS of the BRAIN.
The movement and the forces involved in the movement of the blood through the CARDIOVASCULAR SYSTEM.
The movement of the BLOOD as it is pumped through the CARDIOVASCULAR SYSTEM.
The force that opposes the flow of BLOOD through a vascular bed. It is equal to the difference in BLOOD PRESSURE across the vascular bed divided by the CARDIAC OUTPUT.
The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)
The circulation of blood through the CORONARY VESSELS of the HEART.
The circulation of blood through the BLOOD VESSELS supplying the abdominal VISCERA.
PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS.
Scandium. An element of the rare earth family of metals. It has the atomic symbol Sc, atomic number 21, and atomic weight 45.
The circulation of the BLOOD through the vessels of the KIDNEY.
The circulation of BLOOD through the LIVER.
The circulation of the BLOOD through the LUNGS.
A method of non-invasive, continuous measurement of MICROCIRCULATION. The technique is based on the values of the DOPPLER EFFECT of low-power laser light scattered randomly by static structures and moving tissue particulates.
Unstable isotopes of xenon that decay or disintegrate emitting radiation. Xe atoms with atomic weights 121-123, 125, 127, 133, 135, 137-145 are radioactive xenon isotopes.
The number of times the HEART VENTRICLES contract per unit of time, usually per minute.
A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures.
An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.
Measurement of oxygen and carbon dioxide in the blood.
Isotopes that exhibit radioactivity and undergo radioactive decay. (From Grant & Hackh's Chemical Dictionary, 5th ed & McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
A drug used in the management of peripheral and cerebral vascular disorders. It is claimed to enhance cellular oxidative capacity and to be a spasmolytic. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1310) It may also be an antagonist at 5HT-2 serotonin receptors.
The rate at which oxygen is used by a tissue; microliters of oxygen STPD used per milligram of tissue per hour; the rate at which oxygen enters the blood from alveolar gas, equal in the steady state to the consumption of oxygen by tissue metabolism throughout the body. (Stedman, 25th ed, p346)
Unstable isotopes of nitrogen that decay or disintegrate emitting radiation. N atoms with atomic weights 12, 13, 16, 17, and 18 are radioactive nitrogen isotopes.
Tomography using radioactive emissions from injected RADIONUCLIDES and computer ALGORITHMS to reconstruct an image.
A nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAUD DISEASE and frostbite, clonidine withdrawal syndrome, impotence, and peripheral vascular disease.
The ratio of alveolar ventilation to simultaneous alveolar capillary blood flow in any part of the lung. (Stedman, 25th ed)
Unstable isotopes of oxygen that decay or disintegrate emitting radiation. O atoms with atomic weights 13, 14, 15, 19, and 20 are radioactive oxygen isotopes.
Body organ that filters blood for the secretion of URINE and that regulates ion concentrations.
The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.
Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).
Either of two extremities of four-footed non-primate land animals. It usually consists of a FEMUR; TIBIA; and FIBULA; tarsals; METATARSALS; and TOES. (From Storer et al., General Zoology, 6th ed, p73)
A colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
The circulation of the BLOOD through the MICROVASCULAR NETWORK.
Organic compounds that contain technetium as an integral part of the molecule. These compounds are often used as radionuclide imaging agents.
The placing of a body or a part thereof into a liquid.
The physiological narrowing of BLOOD VESSELS by contraction of the VASCULAR SMOOTH MUSCLE.
The pressure that would be exerted by one component of a mixture of gases if it were present alone in a container. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
Theoretical representations that simulate the behavior or activity of the cardiovascular system, processes, or phenomena; includes the use of mathematical equations, computers and other electronic equipment.
Either of two large arteries originating from the abdominal aorta; they supply blood to the pelvis, abdominal wall and legs.
Volume of circulating BLOOD. It is the sum of the PLASMA VOLUME and ERYTHROCYTE VOLUME.
A branch of the abdominal aorta which supplies the kidneys, adrenal glands and ureters.
A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.
The physiological widening of BLOOD VESSELS by relaxing the underlying VASCULAR SMOOTH MUSCLE.
The exchange of OXYGEN and CARBON DIOXIDE between alveolar air and pulmonary capillary blood that occurs across the BLOOD-AIR BARRIER.
Drugs used to cause dilation of the blood vessels.
The posture of an individual lying face up.
Anesthesia caused by the breathing of anesthetic gases or vapors or by insufflating anesthetic gases or vapors into the respiratory tract.
Elements of limited time intervals, contributing to particular results or situations.
A non-selective inhibitor of nitric oxide synthase. It has been used experimentally to induce hypertension.
The hollow, muscular organ that maintains the circulation of the blood.
Maintenance of blood flow to an organ despite obstruction of a principal vessel. Blood flow is maintained through small vessels.
The muscle tissue of the HEART. It is composed of striated, involuntary muscle cells (MYOCYTES, CARDIAC) connected to form the contractile pump to generate blood flow.
A stable, non-explosive inhalation anesthetic, relatively free from significant side effects.
The inferior part of the lower extremity between the KNEE and the ANKLE.
The administration of liquid medication, nutrient, or other fluid through some other route than the alimentary canal, usually over minutes or hours, either by gravity flow or often by infusion pumping.
A free radical gas produced endogenously by a variety of mammalian cells, synthesized from ARGININE by NITRIC OXIDE SYNTHASE. Nitric oxide is one of the ENDOTHELIUM-DEPENDENT RELAXING FACTORS released by the vascular endothelium and mediates VASODILATION. It also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic GUANYLATE CYCLASE and thus elevates intracellular levels of CYCLIC GMP.
Arteries which arise from the abdominal aorta and distribute to most of the intestines.
The domestic cat, Felis catus, of the carnivore family FELIDAE, comprising over 30 different breeds. The domestic cat is descended primarily from the wild cat of Africa and extreme southwestern Asia. Though probably present in towns in Palestine as long ago as 7000 years, actual domestication occurred in Egypt about 4000 years ago. (From Walker's Mammals of the World, 6th ed, p801)
Technique using an instrument system for making, processing, and displaying one or more measurements on individual cells obtained from a cell suspension. Cells are usually stained with one or more fluorescent dyes specific to cell components of interest, e.g., DNA, and fluorescence of each cell is measured as it rapidly transverses the excitation beam (laser or mercury arc lamp). Fluorescence provides a quantitative measure of various biochemical and biophysical properties of the cell, as well as a basis for cell sorting. Other measurable optical parameters include light absorption and light scattering, the latter being applicable to the measurement of cell size, shape, density, granularity, and stain uptake.
A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.
A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
A method of computed tomography that uses radionuclides which emit a single photon of a given energy. The camera is rotated 180 or 360 degrees around the patient to capture images at multiple positions along the arc. The computer is then used to reconstruct the transaxial, sagittal, and coronal images from the 3-dimensional distribution of radionuclides in the organ. The advantages of SPECT are that it can be used to observe biochemical and physiological processes as well as size and volume of the organ. The disadvantage is that, unlike positron-emission tomography where the positron-electron annihilation results in the emission of 2 photons at 180 degrees from each other, SPECT requires physical collimation to line up the photons, which results in the loss of many available photons and hence degrades the image.
Part of the arm in humans and primates extending from the ELBOW to the WRIST.
The thoracolumbar division of the autonomic nervous system. Sympathetic preganglionic fibers originate in neurons of the intermediolateral column of the spinal cord and project to the paravertebral and prevertebral ganglia, which in turn project to target organs. The sympathetic nervous system mediates the body's response to stressful situations, i.e., the fight or flight reactions. It often acts reciprocally to the parasympathetic system.
A subtype of striated muscle, attached by TENDONS to the SKELETON. Skeletal muscles are innervated and their movement can be consciously controlled. They are also called voluntary muscles.
Any of the ruminant mammals with curved horns in the genus Ovis, family Bovidae. They possess lachrymal grooves and interdigital glands, which are absent in GOATS.
Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus. It is also found in plants and is used pharmacologically as a sympathomimetic.
A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain.
Genetically identical individuals developed from brother and sister matings which have been carried out for twenty or more generations or by parent x offspring matings carried out with certain restrictions. This also includes animals with a long history of closed colony breeding.
Injections made into a vein for therapeutic or experimental purposes.
An NADPH-dependent enzyme that catalyzes the conversion of L-ARGININE and OXYGEN to produce CITRULLINE and NITRIC OXIDE.
Rhythmic, intermittent propagation of a fluid through a BLOOD VESSEL or piping system, in contrast to constant, smooth propagation, which produces laminar flow.
The species Oryctolagus cuniculus, in the family Leporidae, order LAGOMORPHA. Rabbits are born in burrows, furless, and with eyes and ears closed. In contrast with HARES, rabbits have 22 chromosome pairs.
The relationship between the dose of an administered drug and the response of the organism to the drug.
The veins and arteries of the HEART.
Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.
Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.
The range or frequency distribution of a measurement in a population (of organisms, organs or things) that has not been selected for the presence of disease or abnormality.
The vessels carrying blood away from the heart.
Either of the pair of organs occupying the cavity of the thorax that effect the aeration of the blood.
Contractile activity of the MYOCARDIUM.
The minute vessels that connect the arterioles and venules.
'Blood donors' are individuals who voluntarily and safely donate a specific amount of their own blood, which can be further separated into components, to be used for transfusion purposes or for manufacturing medical products, without receiving remuneration that is intended to reward them financially.
Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.
NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION).
An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.
The study of the deformation and flow of matter, usually liquids or fluids, and of the plastic flow of solids. The concept covers consistency, dilatancy, liquefaction, resistance to flow, shearing, thixotrophy, and VISCOSITY.
Relatively complete absence of oxygen in one or more tissues.
The presence of an increased amount of blood in a body part or an organ leading to congestion or engorgement of blood vessels. Hyperemia can be due to increase of blood flow into the area (active or arterial), or due to obstruction of outflow of blood from the area (passive or venous).
Ultrasonography applying the Doppler effect, with frequency-shifted ultrasound reflections produced by moving targets (usually red blood cells) in the bloodstream along the ultrasound axis in direct proportion to the velocity of movement of the targets, to determine both direction and velocity of blood flow. (Stedman, 25th ed)
A noble gas with the atomic symbol Xe, atomic number 54, and atomic weight 131.30. It is found in the earth's atmosphere and has been used as an anesthetic.
The change in gene frequency in a population due to migration of gametes or individuals (ANIMAL MIGRATION) across population barriers. In contrast, in GENETIC DRIFT the cause of gene frequency changes are not a result of population or gamete movement.
Determination of the shortest time interval between the injection of a substance in the vein and its arrival at some distant site in sufficient concentration to produce a recognizable end result. It represents approximately the inverse of the average velocity of blood flow between two points.
Ultrasonography applying the Doppler effect, with the superposition of flow information as colors on a gray scale in a real-time image. This type of ultrasonography is well-suited to identifying the location of high-velocity flow (such as in a stenosis) or of mapping the extent of flow in a certain region.
Recording of change in the size of a part as modified by the circulation in it.
The position or attitude of the body.
The arterial blood vessels supplying the CEREBRUM.
Substances used to allow enhanced visualization of tissues.
A non-invasive technique using ultrasound for the measurement of cerebrovascular hemodynamics, particularly cerebral blood flow velocity and cerebral collateral flow. With a high-intensity, low-frequency pulse probe, the intracranial arteries may be studied transtemporally, transorbitally, or from below the foramen magnum.
Drugs that bind to but do not activate beta-adrenergic receptors thereby blocking the actions of beta-adrenergic agonists. Adrenergic beta-antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches, and anxiety.
The largest of the cerebral arteries. It trifurcates into temporal, frontal, and parietal branches supplying blood to most of the parenchyma of these lobes in the CEREBRAL CORTEX. These are the areas involved in motor, sensory, and speech activities.
The blood vessels which supply and drain the RETINA.
An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
Treatment process involving the injection of fluid into an organ or tissue.
The thin, highly vascular membrane covering most of the posterior of the eye between the RETINA and SCLERA.
The TEMPERATURE at the outer surface of the body.
The neural systems which act on VASCULAR SMOOTH MUSCLE to control blood vessel diameter. The major neural control is through the sympathetic nervous system.
The main artery of the thigh, a continuation of the external iliac artery.
Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.
The outer covering of the body that protects it from the environment. It is composed of the DERMIS and the EPIDERMIS.
A nucleoside that is composed of ADENINE and D-RIBOSE. Adenosine or adenosine derivatives play many important biological roles in addition to being components of DNA and RNA. Adenosine itself is a neurotransmitter.

Intrarenal site of action of calcium on renin secretion in dogs. (1/9283)

We studied the effects of intrarenal calcium infusion on renin secretion in sodium-depleted dogs in an attempt to elucidate the major site of calcium-induced inhibition of renin release. Both calcium chloride and calcium gluconate reduced renal blood flow and renin secretion while renal perfusion pressure was unchanged. These data indicate that calcium inhibition of renin secretion did not occur primarily at the renal vascular receptor; decreased renal blood flow is usually associated with increased renin secretion. Calcium chloride infusion increased urinary chloride excretion without affecting sodium excretion, and calcium gluconate failed to increase either sodium or chloride excretion. Also, the filtered loads of sodium and chloride were unchanged during the calcium infusions. These results give no indication that calcium inhibited renin secretion by increasing the sodium or chloride load at the macula densa. The effects of intrarenal calcium infusion on renin release were also assessed in dogs with a nonfiltering kidney in which renal tubular mechanisms could not influence renin secretion. The observation that calcium still suppressed renin release in these dogs provides additional evidence that the the major effect of calcium involved nontubular mechanisms. Thus, it appears likely that calcium acted directly on the juxtaglomerular cells to inhibit renin secretion.  (+info)

Vascular remodeling in response to altered blood flow is mediated by fibroblast growth factor-2. (2/9283)

Vascular structures adapt to changes in blood flow by adjusting their diameter accordingly. The factors mediating this process are only beginning to be identified. We have recently established a mouse model of arterial remodeling in which flow in the common carotid artery is interrupted by ligation of the vessel near the carotid bifurcation, resulting in a dramatic reduction in vessel diameter as a consequence of inward remodeling and intimal lesion formation. In the present study, we used this model to determine the role of fibroblast growth factor-2 (FGF-2) in the remodeling response by maintaining neutralizing serum levels of a mouse monoclonal antibody against FGF-2 for 4 weeks. Morphometric analysis revealed that intimal lesion formation was not affected by the antibody. However, lumen narrowing was significantly inhibited, resulting in a greater than 3-fold increase in lumen area in anti-FGF-2-treated animals compared with controls. Treatment with anti-FGF-2 antibody significantly inhibited the reduction in vessel diameter (inward remodeling) and shortening of the internal elastic lamina in the ligated vessel. In addition, anti-FGF-2 treatment also caused outward remodeling of the contralateral carotid artery. These findings identify FGF-2 as an important factor in vascular remodeling, and its effects are likely to be mediated by increasing vascular tone. The results are consistent with the recent observation of reduced vascular tone in the FGF-2-deficient mouse.  (+info)

Role of endothelin in the increased vascular tone of patients with essential hypertension. (3/9283)

We investigated the possible role of endothelin in the increased vasoconstrictor tone of hypertensive patients using antagonists of endothelin receptors. Forearm blood flow (FBF) responses (strain-gauge plethysmography) to intraarterial infusion of blockers of endothelin-A (ETA) (BQ-123) and endothelin-B (ETB) (BQ-788) receptors, separately and in combination, were measured in hypertensive patients and normotensive control subjects. In healthy subjects, BQ-123 alone or in combination with BQ-788 did not significantly modify FBF (P=0.78 and P=0.63, respectively). In hypertensive patients, in contrast, BQ-123 increased FBF by 33+/-7% (P<0.001 versus baseline), and the combination of BQ-123 and BQ-788 resulted in a greater vasodilator response (63+/-12%; P=0.006 versus BQ-123 alone in the same subjects). BQ-788 produced a divergent vasoactive effect in the two groups, with a decrease of FBF (17+/-5%; P=0.004 versus baseline) in control subjects and transient vasodilation (15+/-7% after 20 minutes) in hypertensive patients (P<0.001, hypertensives versus controls). The vasoconstrictor response to endothelin-1 was slightly higher (P=0.04) in hypertensive patients (46+/-4%) than in control subjects (32+/-4%). Our data indicate that patients with essential hypertension have increased vascular endothelin activity, which may be of pathophysiological relevance to their increased vascular tone. In these patients, nonselective ETA and ETB blockade seems to produce a greater vasodilator effect than selective ETA blockade.  (+info)

Bronchial artery perfusion scintigraphy to assess bronchial artery blood flow after lung transplantation. (4/9283)

The bronchial arterial system is inevitably interrupted in transplanted lungs when removing the organs from the donor, but it can be reestablished by direct bronchial artery revascularization (BAR) during implantation. The purpose of this study was to visualize and quantify the distribution of bronchial artery perfusion after en bloc double lung transplantation with BAR, by injecting radiolabeled macroaggregated albumin directly into the bronchial artery system. METHODS: BAR was performed using the internal mammary artery as conduit. Patients were imaged 1 mo (n = 13) or 2 y (n = 9) after en bloc double lung transplantation with BAR. Immediately after bronchial arteriography, 100 MBq macroaggregated albumin (45,000 particles) were injected through the arteriographic catheter. Gamma camera studies were then acquired in the anterior position. At the end of imaging, with the patient remaining in exactly the same position, 81mKr-ventilation scintigraphy or conventional intravenous pulmonary perfusion scintigraphy or both were performed. Images were evaluated by visual analysis, and a semiquantitative assessment of the bronchial arterial supply to the peripheral parts of the lungs was obtained with conventional pulmonary scintigraphy. RESULTS: The bronchial artery scintigraphic images showed that the major part of the bronchial arterial flow supplied central thoracic structures, but bronchial artery perfusion could also be demonstrated in the peripheral parts of the lungs when compared with conventional pulmonary scintigraphy. There were no differences between scintigrams obtained from patients studied 1 mo and 2 y post-transplantation. CONCLUSION: Total distribution of bronchial artery supply to the human lung has been visualized in lung transplant patients. This study demonstrates that this nutritive flow reaches even the most peripheral parts of the lungs and is present 1 mo as well as 2 y after lung transplantation. The results suggest that bronchial artery revascularization may be of significance for the long-term status of the lung transplant.  (+info)

Pulsed Doppler ultrasonographic evaluation of portal blood flow in dogs with experimental portal vein branch ligation. (5/9283)

Portal blood flow was measured using pulsed Doppler ultrasound in 6 dogs before and after left portal vein branch ligation. Mean portal vein blood flow velocity and mean portal vein blood flow were significantly reduced after ligation and the congestion index was increased (p < 0.01). Pulsed Doppler ultrasound studies provide valuable physiological information which may assist the clinician with the diagnosis of canine hepatic circulatory disorders.  (+info)

Rescue of diabetes-related impairment of angiogenesis by intramuscular gene therapy with adeno-VEGF. (6/9283)

Diabetes is a major risk factor for coronary and peripheral artery diseases. Although diabetic patients often present with advanced forms of these diseases, it is not known whether the compensatory mechanisms to vascular ischemia are affected in this condition. Accordingly, we sought to determine whether diabetes could: 1) impair the development of new collateral vessel formation in response to tissue ischemia and 2) inhibit cytokine-induced therapeutic neovascularization. Hindlimb ischemia was created by femoral artery ligation in nonobese diabetic mice (NOD mice, n = 20) and in control C57 mice (n = 20). Hindlimb perfusion was evaluated by serial laser Doppler studies after the surgery. In NOD mice, measurement of the Doppler flow ratio between the ischemic and the normal limb indicated that restoration of perfusion in the ischemic hindlimb was significantly impaired. At day 14 after surgery, Doppler flow ratio in the NOD mice was 0.49+/-0.04 versus 0.73+/-0.06 for the C57 mice (P< or =0.005). This impairment in blood flow recovery persisted throughout the duration of the study with Doppler flow ratio values at day 35 of 0.50+/-0.05 versus 0.90+/-0.07 in the NOD and C57 mice, respectively (P< or =0.001). CD31 immunostaining confirmed the laser Doppler data by showing a significant reduction in capillary density in the NOD mice at 35 days after surgery (302+/-4 capillaries/mm2 versus 782+/-78 in C57 mice (P< or =0.005). The reduction in neovascularization in the NOD mice was the result of a lower level of vascular endothelial growth factor (VEGF) in the ischemic tissues, as assessed by Northern blot, Western blot and immunohistochemistry. The central role of VEGF was confirmed by showing that normal levels of neovascularization (compared with C57) could be achieved in NOD mice that had been supplemented for this growth factor via intramuscular injection of an adenoviral vector encoding for VEGF. We conclude that 1) diabetes impairs endogenous neovascularization of ischemic tissues; 2) the impairment in new blood vessel formation results from reduced expression of VEGF; and 3) cytokine supplementation achieved by intramuscular adeno-VEGF gene transfer restores neovascularization in a mouse model of diabetes.  (+info)

Sonographic evidence for the involvement of the utero-ovarian counter-current system in the ovarian control of directed uterine sperm transport. (7/9283)

Sperm transport from the cervix into the tube is an important uterine function within the process of reproduction. This function is exerted by uterine peristalsis and is controlled by the dominant ovarian structure via a cascade of endocrine events. The uterine peristaltic activity involves only the stratum subvasculare of the myometrium, which exhibits a predominantly circular arrangement of muscular fibres that separate at the fundal level into the fibres of the cornua and continue into the circular muscles of the respective tubes. Since spermatozoa are transported preferentially into the tube ipsilateral to the dominant follicle, this asymmetric uterine function may be controlled by the ovary via direct effects utilizing the utero-ovarian counter-current system, in addition to the systemic circulation. To test this possibility the sonographic characteristics of the uterine vascular bed were studied during different phases of the menstrual cycle. Vaginal sonography with the measurement of Doppler flow characteristics of both uterine arteries and of the arterial anastomoses of the uterine and ovarian arteries (junctional vessels) in the cornual region of both sides of the uterus during the menstrual phase of regular-cycling women demonstrated significant lower resistance indices of the junctional vessels ipsilateral to the side of the dominant ovarian structure as compared with the corresponding arteries contralaterally. By the use of the perfusion mode technique, it could be observed that vascular perfusion of the fundal myometrium was significantly increased ipsilateral to the dominant follicle during the late follicular phase of the cycle. These results show that the endocrine control of the dominant ovarian structure over uterine function is not only exerted via the systemic circulation but also directly, most probably utilizing the utero-ovarian counter-current system.  (+info)

Endothelial function in Marfan syndrome: selective impairment of flow-mediated vasodilation. (8/9283)

BACKGROUND: The cardiovascular complications of Marfan syndrome arise due to alterations in the structural and functional properties of fibrillin, a constituent of vascular connective tissues. Fibrillin-containing microfibrils are closely associated with arterial endothelial cells, indicating a possible functional role for fibrillin in the endothelium. Plasma concentrations of endothelial cell products are elevated in Marfan subjects, which indirectly indicates endothelial dysfunction. This study directly assessed flow- and agonist-mediated endothelium-dependent brachial artery reactivity in Marfan subjects. METHODS AND RESULTS: In 20 Marfan and 20 control subjects, brachial artery diameter, blood flow, and blood pressure were measured by ultrasonic wall tracking, Doppler ultrasound, and photoplethysmography, respectively. Measurements were taken during hand hyperemia (a stimulus for endothelium-derived nitric oxide [NO] release in the upstream brachial artery) and after sublingual administration of the endothelium-independent vasodilator nitroglycerin. In 9 Marfan and 6 control subjects, the above parameters were also assessed during intra-arterial infusions of acetylcholine and bradykinin (agonists that stimulate NO production) and NG-monomethyl-L-arginine (L-NMMA, an inhibitor of NO production). Flow-mediated responses differed markedly between Marfan and control subjects (-1.6+/-3.5% versus 6. 50+/-4.1%, respectively; P<0.0001), whereas nitroglycerin produced similar vasodilation (14.2+/-5.7% versus 15.2+/-7.8%; P=NS). Agonist-induced vasodilation to incremental intra-arterial infusions of acetylcholine and bradykinin were not significantly different between Marfan and control subjects, and intra-arterial L-NMMA produced similar reductions in brachial artery diameter in both groups. CONCLUSIONS: These data demonstrate impaired flow-mediated but preserved agonist-mediated endothelium-dependent vasodilation in Marfan subjects and suggest preservation of basal NO release. Selective loss of flow-mediated dilation suggests a role for fibrillin in endothelial cell mechanotransduction.  (+info)

Regional blood flow (RBF) refers to the rate at which blood flows through a specific region or organ in the body, typically expressed in milliliters per minute per 100 grams of tissue (ml/min/100g). It is an essential physiological parameter that reflects the delivery of oxygen and nutrients to tissues while removing waste products. RBF can be affected by various factors such as metabolic demands, neural regulation, hormonal influences, and changes in blood pressure or vascular resistance. Measuring RBF is crucial for understanding organ function, diagnosing diseases, and evaluating the effectiveness of treatments.

Microspheres are tiny, spherical particles that range in size from 1 to 1000 micrometers in diameter. They are made of biocompatible and biodegradable materials such as polymers, glass, or ceramics. In medical terms, microspheres have various applications, including drug delivery systems, medical imaging, and tissue engineering.

In drug delivery, microspheres can be used to encapsulate drugs and release them slowly over time, improving the efficacy of the treatment while reducing side effects. They can also be used for targeted drug delivery, where the microspheres are designed to accumulate in specific tissues or organs.

In medical imaging, microspheres can be labeled with radioactive isotopes or magnetic materials and used as contrast agents to enhance the visibility of tissues or organs during imaging procedures such as X-ray, CT, MRI, or PET scans.

In tissue engineering, microspheres can serve as a scaffold for cell growth and differentiation, promoting the regeneration of damaged tissues or organs. Overall, microspheres have great potential in various medical applications due to their unique properties and versatility.

Blood flow velocity is the speed at which blood travels through a specific part of the vascular system. It is typically measured in units of distance per time, such as centimeters per second (cm/s) or meters per second (m/s). Blood flow velocity can be affected by various factors, including cardiac output, vessel diameter, and viscosity of the blood. Measuring blood flow velocity is important in diagnosing and monitoring various medical conditions, such as heart disease, stroke, and peripheral vascular disease.

Cardiac output is a measure of the amount of blood that is pumped by the heart in one minute. It is defined as the product of stroke volume (the amount of blood pumped by the left ventricle during each contraction) and heart rate (the number of contractions per minute). Normal cardiac output at rest for an average-sized adult is about 5 to 6 liters per minute. Cardiac output can be increased during exercise or other conditions that require more blood flow, such as during illness or injury. It can be measured noninvasively using techniques such as echocardiography or invasively through a catheter placed in the heart.

Cerebrovascular circulation refers to the network of blood vessels that supply oxygenated blood and nutrients to the brain tissue, and remove waste products. It includes the internal carotid arteries, vertebral arteries, circle of Willis, and the intracranial arteries that branch off from them.

The internal carotid arteries and vertebral arteries merge to form the circle of Willis, a polygonal network of vessels located at the base of the brain. The anterior cerebral artery, middle cerebral artery, posterior cerebral artery, and communicating arteries are the major vessels that branch off from the circle of Willis and supply blood to different regions of the brain.

Interruptions or abnormalities in the cerebrovascular circulation can lead to various neurological conditions such as stroke, transient ischemic attack (TIA), and vascular dementia.

Hemodynamics is the study of how blood flows through the cardiovascular system, including the heart and the vascular network. It examines various factors that affect blood flow, such as blood volume, viscosity, vessel length and diameter, and pressure differences between different parts of the circulatory system. Hemodynamics also considers the impact of various physiological and pathological conditions on these variables, and how they in turn influence the function of vital organs and systems in the body. It is a critical area of study in fields such as cardiology, anesthesiology, and critical care medicine.

Blood circulation, also known as cardiovascular circulation, refers to the process by which blood is pumped by the heart and circulated throughout the body through a network of blood vessels, including arteries, veins, and capillaries. This process ensures that oxygen and nutrients are delivered to cells and tissues, while waste products and carbon dioxide are removed.

The circulation of blood can be divided into two main parts: the pulmonary circulation and the systemic circulation. The pulmonary circulation involves the movement of blood between the heart and the lungs, where it picks up oxygen and releases carbon dioxide. The systemic circulation refers to the movement of blood between the heart and the rest of the body, delivering oxygen and nutrients to cells and tissues while picking up waste products for removal.

The heart plays a central role in blood circulation, acting as a pump that contracts and relaxes to move blood through the body. The contraction of the heart's left ventricle pushes oxygenated blood into the aorta, which then branches off into smaller arteries that carry blood throughout the body. The blood then flows through capillaries, where it exchanges oxygen and nutrients for waste products and carbon dioxide with surrounding cells and tissues. The deoxygenated blood is then collected in veins, which merge together to form larger vessels that eventually return the blood back to the heart's right atrium. From there, the blood is pumped into the lungs to pick up oxygen and release carbon dioxide, completing the cycle of blood circulation.

Vascular resistance is a measure of the opposition to blood flow within a vessel or a group of vessels, typically expressed in units of mmHg/(mL/min) or sometimes as dynes*sec/cm^5. It is determined by the diameter and length of the vessels, as well as the viscosity of the blood flowing through them. In general, a decrease in vessel diameter, an increase in vessel length, or an increase in blood viscosity will result in an increase in vascular resistance, while an increase in vessel diameter, a decrease in vessel length, or a decrease in blood viscosity will result in a decrease in vascular resistance. Vascular resistance is an important concept in the study of circulation and cardiovascular physiology because it plays a key role in determining blood pressure and blood flow within the body.

I believe there might be a misunderstanding in your question. "Dogs" is not a medical term or condition. It is the common name for a domesticated carnivore of the family Canidae, specifically the genus Canis, which includes wolves, foxes, and other extant and extinct species of mammals. Dogs are often kept as pets and companions, and they have been bred in a wide variety of forms and sizes for different purposes, such as hunting, herding, guarding, assisting police and military forces, and providing companionship and emotional support.

If you meant to ask about a specific medical condition or term related to dogs, please provide more context so I can give you an accurate answer.

Coronary circulation refers to the circulation of blood in the coronary vessels, which supply oxygenated blood to the heart muscle (myocardium) and drain deoxygenated blood from it. The coronary circulation system includes two main coronary arteries - the left main coronary artery and the right coronary artery - that branch off from the aorta just above the aortic valve. These arteries further divide into smaller branches, which supply blood to different regions of the heart muscle.

The left main coronary artery divides into two branches: the left anterior descending (LAD) artery and the left circumflex (LCx) artery. The LAD supplies blood to the front and sides of the heart, while the LCx supplies blood to the back and sides of the heart. The right coronary artery supplies blood to the lower part of the heart, including the right ventricle and the bottom portion of the left ventricle.

The veins that drain the heart muscle include the great cardiac vein, the middle cardiac vein, and the small cardiac vein, which merge to form the coronary sinus. The coronary sinus empties into the right atrium, allowing deoxygenated blood to enter the right side of the heart and be pumped to the lungs for oxygenation.

Coronary circulation is essential for maintaining the health and function of the heart muscle, as it provides the necessary oxygen and nutrients required for proper contraction and relaxation of the myocardium. Any disruption or blockage in the coronary circulation system can lead to serious consequences, such as angina, heart attack, or even death.

Splanchnic circulation refers to the blood flow to the visceral organs, including the gastrointestinal tract, pancreas, spleen, and liver. These organs receive a significant portion of the cardiac output, with approximately 25-30% of the total restingly going to the splanchnic circulation. The splanchnic circulation is regulated by a complex interplay of neural and hormonal mechanisms that help maintain adequate blood flow to these vital organs while also allowing for the distribution of blood to other parts of the body as needed.

The splanchnic circulation is unique in its ability to vasodilate and increase blood flow significantly in response to meals or other stimuli, such as stress or hormonal changes. This increased blood flow helps support the digestive process and absorption of nutrients. At the same time, the body must carefully regulate this blood flow to prevent a significant drop in blood pressure or overloading the heart with too much work.

Overall, the splanchnic circulation plays a critical role in maintaining the health and function of the body's vital organs, and dysregulation of this system can contribute to various diseases, including digestive disorders, liver disease, and cardiovascular disease.

Blood pressure is the force exerted by circulating blood on the walls of the blood vessels. It is measured in millimeters of mercury (mmHg) and is given as two figures:

1. Systolic pressure: This is the pressure when the heart pushes blood out into the arteries.
2. Diastolic pressure: This is the pressure when the heart rests between beats, allowing it to fill with blood.

Normal blood pressure for adults is typically around 120/80 mmHg, although this can vary slightly depending on age, sex, and other factors. High blood pressure (hypertension) is generally considered to be a reading of 130/80 mmHg or higher, while low blood pressure (hypotension) is usually defined as a reading below 90/60 mmHg. It's important to note that blood pressure can fluctuate throughout the day and may be affected by factors such as stress, physical activity, and medication use.

I'm sorry for any confusion, but "Scandium" is not a medical term. It is a chemical element with the symbol Sc and atomic number 21. It is a silvery-white metal that is soft, workable, and highly resistant to corrosion. In medicine, scandium and its compounds are not used in therapy or diagnosis.

Renal circulation refers to the blood flow specifically dedicated to the kidneys. The main function of the kidneys is to filter waste and excess fluids from the blood, which then get excreted as urine. To perform this function efficiently, the kidneys receive a substantial amount of the body's total blood supply - about 20-25% in a resting state.

The renal circulation process begins when deoxygenated blood from the rest of the body returns to the right side of the heart and is pumped into the lungs for oxygenation. Oxygen-rich blood then leaves the left side of the heart through the aorta, the largest artery in the body.

A portion of this oxygen-rich blood moves into the renal arteries, which branch directly from the aorta and supply each kidney with blood. Within the kidneys, these arteries divide further into smaller vessels called afferent arterioles, which feed into a network of tiny capillaries called the glomerulus within each nephron (the functional unit of the kidney).

The filtration process occurs in the glomeruli, where waste materials and excess fluids are separated from the blood. The resulting filtrate then moves through another set of capillaries, the peritubular capillaries, which surround the renal tubules (the part of the nephron that reabsorbs necessary substances back into the bloodstream).

The now-deoxygenated blood from the kidneys' capillary network coalesces into venules and then merges into the renal veins, which ultimately drain into the inferior vena cava and return the blood to the right side of the heart. This highly specialized circulation system allows the kidneys to efficiently filter waste while maintaining appropriate blood volume and composition.

Liver circulation, also known as hepatic circulation, refers to the blood flow through the liver. The liver receives blood from two sources: the hepatic artery and the portal vein.

The hepatic artery delivers oxygenated blood from the heart to the liver, accounting for about 25% of the liver's blood supply. The remaining 75% comes from the portal vein, which carries nutrient-rich, deoxygenated blood from the gastrointestinal tract, spleen, pancreas, and gallbladder to the liver.

In the liver, these two sources of blood mix in the sinusoids, small vessels with large spaces between the endothelial cells that line them. This allows for efficient exchange of substances between the blood and the hepatocytes (liver cells). The blood then leaves the liver through the hepatic veins, which merge into the inferior vena cava and return the blood to the heart.

The unique dual blood supply and extensive sinusoidal network in the liver enable it to perform various critical functions, such as detoxification, metabolism, synthesis, storage, and secretion of numerous substances, maintaining body homeostasis.

Pulmonary circulation refers to the process of blood flow through the lungs, where blood picks up oxygen and releases carbon dioxide. This is a vital part of the overall circulatory system, which delivers nutrients and oxygen to the body's cells while removing waste products like carbon dioxide.

In pulmonary circulation, deoxygenated blood from the systemic circulation returns to the right atrium of the heart via the superior and inferior vena cava. The blood then moves into the right ventricle through the tricuspid valve and gets pumped into the pulmonary artery when the right ventricle contracts.

The pulmonary artery divides into smaller vessels called arterioles, which further branch into a vast network of tiny capillaries in the lungs. Here, oxygen from the alveoli diffuses into the blood, binding to hemoglobin in red blood cells, while carbon dioxide leaves the blood and is exhaled through the nose or mouth.

The now oxygenated blood collects in venules, which merge to form pulmonary veins. These veins transport the oxygen-rich blood back to the left atrium of the heart, where it enters the systemic circulation once again. This continuous cycle enables the body's cells to receive the necessary oxygen and nutrients for proper functioning while disposing of waste products.

Laser-Doppler flowmetry (LDF) is a non-invasive, investigative technique used to measure microcirculatory blood flow in real time. It is based on the principle of the Doppler effect, which describes the change in frequency or wavelength of light or sound waves as they encounter a moving object or reflect off a moving surface.

In LDF, a low-power laser beam is directed at the skin or other transparent tissue. The light penetrates the tissue and scatters off the moving red blood cells within the microvasculature. As the light scatters, it undergoes a slight frequency shift due to the movement of the red blood cells. This frequency shift is then detected by a photodetector, which converts it into an electrical signal. The magnitude of this signal is directly proportional to the speed and concentration of the moving red blood cells, providing a measure of microcirculatory blood flow.

LDF has various clinical applications, including the assessment of skin perfusion in patients with peripheral arterial disease, burn injuries, and flaps used in reconstructive surgery. It can also be used to study the effects of drugs or other interventions on microcirculation in research settings.

Xenon radioisotopes are unstable isotopes of the element xenon that emit radiation as they decay into more stable forms. These isotopes can be produced through various nuclear reactions and have a wide range of applications, including medical imaging and cancer treatment. Examples of commonly used xenon radioisotopes include xenon-127, xenon-131m, xenon-133, and xenon-135.

It's important to note that the use of radioisotopes in medical settings must be carefully regulated and monitored to ensure safety and minimize potential risks to patients and healthcare workers.

Heart rate is the number of heartbeats per unit of time, often expressed as beats per minute (bpm). It can vary significantly depending on factors such as age, physical fitness, emotions, and overall health status. A resting heart rate between 60-100 bpm is generally considered normal for adults, but athletes and individuals with high levels of physical fitness may have a resting heart rate below 60 bpm due to their enhanced cardiovascular efficiency. Monitoring heart rate can provide valuable insights into an individual's health status, exercise intensity, and response to various treatments or interventions.

Anesthesia is a medical term that refers to the loss of sensation or awareness, usually induced by the administration of various drugs. It is commonly used during surgical procedures to prevent pain and discomfort. There are several types of anesthesia, including:

1. General anesthesia: This type of anesthesia causes a complete loss of consciousness and is typically used for major surgeries.
2. Regional anesthesia: This type of anesthesia numbs a specific area of the body, such as an arm or leg, while the patient remains conscious.
3. Local anesthesia: This type of anesthesia numbs a small area of the body, such as a cut or wound, and is typically used for minor procedures.

Anesthesia can be administered through various routes, including injection, inhalation, or topical application. The choice of anesthesia depends on several factors, including the type and duration of the procedure, the patient's medical history, and their overall health. Anesthesiologists are medical professionals who specialize in administering anesthesia and monitoring patients during surgical procedures to ensure their safety and comfort.

Oxygen is a colorless, odorless, tasteless gas that constitutes about 21% of the earth's atmosphere. It is a crucial element for human and most living organisms as it is vital for respiration. Inhaled oxygen enters the lungs and binds to hemoglobin in red blood cells, which carries it to tissues throughout the body where it is used to convert nutrients into energy and carbon dioxide, a waste product that is exhaled.

Medically, supplemental oxygen therapy may be provided to patients with conditions such as chronic obstructive pulmonary disease (COPD), pneumonia, heart failure, or other medical conditions that impair the body's ability to extract sufficient oxygen from the air. Oxygen can be administered through various devices, including nasal cannulas, face masks, and ventilators.

Blood gas analysis is a medical test that measures the levels of oxygen and carbon dioxide in the blood, as well as the pH level, which indicates the acidity or alkalinity of the blood. This test is often used to evaluate lung function, respiratory disorders, and acid-base balance in the body. It can also be used to monitor the effectiveness of treatments for conditions such as chronic obstructive pulmonary disease (COPD), asthma, and other respiratory illnesses. The analysis is typically performed on a sample of arterial blood, although venous blood may also be used in some cases.

Radioisotopes, also known as radioactive isotopes or radionuclides, are variants of chemical elements that have unstable nuclei and emit radiation in the form of alpha particles, beta particles, gamma rays, or conversion electrons. These isotopes are formed when an element's nucleus undergoes natural or artificial radioactive decay.

Radioisotopes can be produced through various processes, including nuclear fission, nuclear fusion, and particle bombardment in a cyclotron or other types of particle accelerators. They have a wide range of applications in medicine, industry, agriculture, research, and energy production. In the medical field, radioisotopes are used for diagnostic imaging, radiation therapy, and in the labeling of molecules for research purposes.

It is important to note that handling and using radioisotopes requires proper training, safety measures, and regulatory compliance due to their ionizing radiation properties, which can pose potential health risks if not handled correctly.

I'm sorry for any confusion, but "Nafronyl" does not appear to be a recognized term in medical terminology or pharmacology. It is possible that there may be a spelling error or typo in the term you are looking for. If you have more information or context about where this term was used, I'd be happy to help you try and find the correct definition.

Oxygen consumption, also known as oxygen uptake, is the amount of oxygen that is consumed or utilized by the body during a specific period of time, usually measured in liters per minute (L/min). It is a common measurement used in exercise physiology and critical care medicine to assess an individual's aerobic metabolism and overall health status.

In clinical settings, oxygen consumption is often measured during cardiopulmonary exercise testing (CPET) to evaluate cardiovascular function, pulmonary function, and exercise capacity in patients with various medical conditions such as heart failure, chronic obstructive pulmonary disease (COPD), and other respiratory or cardiac disorders.

During exercise, oxygen is consumed by the muscles to generate energy through a process called oxidative phosphorylation. The amount of oxygen consumed during exercise can provide important information about an individual's fitness level, exercise capacity, and overall health status. Additionally, measuring oxygen consumption can help healthcare providers assess the effectiveness of treatments and rehabilitation programs in patients with various medical conditions.

Nitrogen radioisotopes are unstable isotopes of the element nitrogen that emit radiation as they decay into more stable forms. Nitrogen has several radioisotopes, with the most common being nitrogen-13 and nitrogen-15. These isotopes have 7 protons in their nucleus, but differ in the number of neutrons.

Nitrogen-13 has a half-life of about 10 minutes, making it useful for medical imaging studies such as positron emission tomography (PET) scans. When nitrogen-13 decays, it emits a positron, which then collides with an electron and produces gamma rays that can be detected by a PET scanner.

Nitrogen-15, on the other hand, has a half-life of about 3 minutes and is not typically used for medical imaging. However, it is widely used in research settings as a stable isotope tracer to study metabolic processes in the body.

It's important to note that handling and using radioisotopes requires specialized training and equipment due to their potential radiation hazards.

Emission computed tomography (ECT) is a type of tomographic imaging technique in which an emission signal from within the body is detected to create cross-sectional images of that signal's distribution. In Emission-Computed Tomography (ECT), a radionuclide is introduced into the body, usually through injection, inhalation or ingestion. The radionuclide emits gamma rays that are then detected by external gamma cameras.

The data collected from these cameras is then used to create cross-sectional images of the distribution of the radiopharmaceutical within the body. This allows for the identification and quantification of functional information about specific organs or systems within the body, such as blood flow, metabolic activity, or receptor density.

One common type of Emission-Computed Tomography is Single Photon Emission Computed Tomography (SPECT), which uses a single gamma camera that rotates around the patient to collect data from multiple angles. Another type is Positron Emission Tomography (PET), which uses positron-emitting radionuclides and detects the coincident gamma rays emitted by the annihilation of positrons and electrons.

Overall, ECT is a valuable tool in medical imaging for diagnosing and monitoring various diseases, including cancer, heart disease, and neurological disorders.

Phentolamine is a non-selective alpha-blocker drug, which means it blocks both alpha-1 and alpha-2 receptors. It works by relaxing the muscle around blood vessels, which increases blood flow and lowers blood pressure. Phentolamine is used medically for various purposes, including the treatment of high blood pressure, the diagnosis and treatment of pheochromocytoma (a tumor that releases hormones causing high blood pressure), and as an antidote to prevent severe hypertension caused by certain medications or substances. It may also be used in diagnostic tests to determine if a patient's blood pressure is reactive to drugs, and it can be used during some surgical procedures to help lower the risk of hypertensive crises.

Phentolamine is available in two forms: an injectable solution and oral tablets. The injectable form is typically administered by healthcare professionals in a clinical setting, while the oral tablets are less commonly used due to their short duration of action and potential for causing severe drops in blood pressure. As with any medication, phentolamine should be taken under the supervision of a healthcare provider, and patients should follow their doctor's instructions carefully to minimize the risk of side effects and ensure the drug's effectiveness.

The Ventilation-Perfusion (V/Q) ratio is a measure used in respiratory physiology to describe the relationship between the amount of air that enters the alveoli (ventilation) and the amount of blood that reaches the alveoli to pick up oxygen (perfusion).

In a healthy lung, these two processes are well-matched, meaning that well-ventilated areas of the lung also have good blood flow. This results in a V/Q ratio close to 1.0.

However, certain lung conditions such as emphysema or pulmonary embolism can cause ventilation and perfusion to become mismatched, leading to a V/Q ratio that is either higher (ventilation exceeds perfusion) or lower (perfusion exceeds ventilation) than normal. This mismatch can result in impaired gas exchange and lead to hypoxemia (low oxygen levels in the blood).

The V/Q ratio is often used in clinical settings to assess lung function and diagnose respiratory disorders.

Oxygen radioisotopes are unstable isotopes of the element oxygen that emit radiation as they decay to a more stable form. These isotopes can be used in medical imaging and treatment, such as positron emission tomography (PET) scans. Common oxygen radioisotopes used in medicine include oxygen-15 and oxygen-18. Oxygen-15 has a very short half-life of about 2 minutes, while oxygen-18 has a longer half-life of about 2 hours. These isotopes can be incorporated into molecules such as water or carbon dioxide, which can then be used to study blood flow, metabolism and other physiological processes in the body.

A kidney, in medical terms, is one of two bean-shaped organs located in the lower back region of the body. They are essential for maintaining homeostasis within the body by performing several crucial functions such as:

1. Regulation of water and electrolyte balance: Kidneys help regulate the amount of water and various electrolytes like sodium, potassium, and calcium in the bloodstream to maintain a stable internal environment.

2. Excretion of waste products: They filter waste products from the blood, including urea (a byproduct of protein metabolism), creatinine (a breakdown product of muscle tissue), and other harmful substances that result from normal cellular functions or external sources like medications and toxins.

3. Endocrine function: Kidneys produce several hormones with important roles in the body, such as erythropoietin (stimulates red blood cell production), renin (regulates blood pressure), and calcitriol (activated form of vitamin D that helps regulate calcium homeostasis).

4. pH balance regulation: Kidneys maintain the proper acid-base balance in the body by excreting either hydrogen ions or bicarbonate ions, depending on whether the blood is too acidic or too alkaline.

5. Blood pressure control: The kidneys play a significant role in regulating blood pressure through the renin-angiotensin-aldosterone system (RAAS), which constricts blood vessels and promotes sodium and water retention to increase blood volume and, consequently, blood pressure.

Anatomically, each kidney is approximately 10-12 cm long, 5-7 cm wide, and 3 cm thick, with a weight of about 120-170 grams. They are surrounded by a protective layer of fat and connected to the urinary system through the renal pelvis, ureters, bladder, and urethra.

The brain is the central organ of the nervous system, responsible for receiving and processing sensory information, regulating vital functions, and controlling behavior, movement, and cognition. It is divided into several distinct regions, each with specific functions:

1. Cerebrum: The largest part of the brain, responsible for higher cognitive functions such as thinking, learning, memory, language, and perception. It is divided into two hemispheres, each controlling the opposite side of the body.
2. Cerebellum: Located at the back of the brain, it is responsible for coordinating muscle movements, maintaining balance, and fine-tuning motor skills.
3. Brainstem: Connects the cerebrum and cerebellum to the spinal cord, controlling vital functions such as breathing, heart rate, and blood pressure. It also serves as a relay center for sensory information and motor commands between the brain and the rest of the body.
4. Diencephalon: A region that includes the thalamus (a major sensory relay station) and hypothalamus (regulates hormones, temperature, hunger, thirst, and sleep).
5. Limbic system: A group of structures involved in emotional processing, memory formation, and motivation, including the hippocampus, amygdala, and cingulate gyrus.

The brain is composed of billions of interconnected neurons that communicate through electrical and chemical signals. It is protected by the skull and surrounded by three layers of membranes called meninges, as well as cerebrospinal fluid that provides cushioning and nutrients.

"Swine" is a common term used to refer to even-toed ungulates of the family Suidae, including domestic pigs and wild boars. However, in a medical context, "swine" often appears in the phrase "swine flu," which is a strain of influenza virus that typically infects pigs but can also cause illness in humans. The 2009 H1N1 pandemic was caused by a new strain of swine-origin influenza A virus, which was commonly referred to as "swine flu." It's important to note that this virus is not transmitted through eating cooked pork products; it spreads from person to person, mainly through respiratory droplets produced when an infected person coughs or sneezes.

A hindlimb, also known as a posterior limb, is one of the pair of extremities that are located distally to the trunk in tetrapods (four-legged vertebrates) and include mammals, birds, reptiles, and amphibians. In humans and other primates, hindlimbs are equivalent to the lower limbs, which consist of the thigh, leg, foot, and toes.

The primary function of hindlimbs is locomotion, allowing animals to move from one place to another. However, they also play a role in other activities such as balance, support, and communication. In humans, the hindlimbs are responsible for weight-bearing, standing, walking, running, and jumping.

In medical terminology, the term "hindlimb" is not commonly used to describe human anatomy. Instead, healthcare professionals use terms like lower limbs or lower extremities to refer to the same region of the body. However, in comparative anatomy and veterinary medicine, the term hindlimb is still widely used to describe the corresponding structures in non-human animals.

Carbon dioxide (CO2) is a colorless, odorless gas that is naturally present in the Earth's atmosphere. It is a normal byproduct of cellular respiration in humans, animals, and plants, and is also produced through the combustion of fossil fuels such as coal, oil, and natural gas.

In medical terms, carbon dioxide is often used as a respiratory stimulant and to maintain the pH balance of blood. It is also used during certain medical procedures, such as laparoscopic surgery, to insufflate (inflate) the abdominal cavity and create a working space for the surgeon.

Elevated levels of carbon dioxide in the body can lead to respiratory acidosis, a condition characterized by an increased concentration of carbon dioxide in the blood and a decrease in pH. This can occur in conditions such as chronic obstructive pulmonary disease (COPD), asthma, or other lung diseases that impair breathing and gas exchange. Symptoms of respiratory acidosis may include shortness of breath, confusion, headache, and in severe cases, coma or death.

Microcirculation is the circulation of blood in the smallest blood vessels, including arterioles, venules, and capillaries. It's responsible for the delivery of oxygen and nutrients to the tissues and the removal of waste products. The microcirculation plays a crucial role in maintaining tissue homeostasis and is regulated by various physiological mechanisms such as autonomic nervous system activity, local metabolic factors, and hormones.

Impairment of microcirculation can lead to tissue hypoxia, inflammation, and organ dysfunction, which are common features in several diseases, including diabetes, hypertension, sepsis, and ischemia-reperfusion injury. Therefore, understanding the structure and function of the microcirculation is essential for developing new therapeutic strategies to treat these conditions.

Organotechnetium compounds are chemical substances that contain carbon-technetium bonds, where technetium is an element with the symbol Tc and atomic number 43. These types of compounds are primarily used in medical imaging as radioactive tracers due to the ability of technetium-99m to emit gamma rays. The organotechnetium compounds help in localizing specific organs, tissues, or functions within the body, making them useful for diagnostic purposes in nuclear medicine.

It is important to note that most organotechnetium compounds are synthesized from technetium-99m, which is generated from the decay of molybdenum-99. The use of these compounds requires proper handling and administration by trained medical professionals due to their radioactive nature.

In medical terms, "immersion" is not a term with a specific clinical definition. However, in general terms, immersion refers to the act of placing something or someone into a liquid or environment completely. In some contexts, it may be used to describe a type of wound care where the wound is covered completely with a medicated dressing or solution. It can also be used to describe certain medical procedures or therapies that involve submerging a part of the body in a liquid, such as hydrotherapy.

Vasoconstriction is a medical term that refers to the narrowing of blood vessels due to the contraction of the smooth muscle in their walls. This process decreases the diameter of the lumen (the inner space of the blood vessel) and reduces blood flow through the affected vessels. Vasoconstriction can occur throughout the body, but it is most noticeable in the arterioles and precapillary sphincters, which control the amount of blood that flows into the capillary network.

The autonomic nervous system, specifically the sympathetic division, plays a significant role in regulating vasoconstriction through the release of neurotransmitters like norepinephrine (noradrenaline). Various hormones and chemical mediators, such as angiotensin II, endothelin-1, and serotonin, can also induce vasoconstriction.

Vasoconstriction is a vital physiological response that helps maintain blood pressure and regulate blood flow distribution in the body. However, excessive or prolonged vasoconstriction may contribute to several pathological conditions, including hypertension, stroke, and peripheral vascular diseases.

In the context of medicine, and specifically in physiology and respiratory therapy, partial pressure (P or p) is a measure of the pressure exerted by an individual gas in a mixture of gases. It's commonly used to describe the concentrations of gases in the body, such as oxygen (PO2), carbon dioxide (PCO2), and nitrogen (PN2).

The partial pressure of a specific gas is calculated as the fraction of that gas in the total mixture multiplied by the total pressure of the mixture. This concept is based on Dalton's law, which states that the total pressure exerted by a mixture of gases is equal to the sum of the pressures exerted by each individual gas.

For example, in room air at sea level, the partial pressure of oxygen (PO2) is approximately 160 mmHg (mm of mercury), which represents about 21% of the total barometric pressure (760 mmHg). This concept is crucial for understanding gas exchange in the lungs and how gases move across membranes, such as from alveoli to blood and vice versa.

Cardiovascular models are simplified representations or simulations of the human cardiovascular system used in medical research, education, and training. These models can be physical, computational, or mathematical and are designed to replicate various aspects of the heart, blood vessels, and blood flow. They can help researchers study the structure and function of the cardiovascular system, test new treatments and interventions, and train healthcare professionals in diagnostic and therapeutic techniques.

Physical cardiovascular models may include artificial hearts, blood vessels, or circulation systems made from materials such as plastic, rubber, or silicone. These models can be used to study the mechanics of heart valves, the effects of different surgical procedures, or the impact of various medical devices on blood flow.

Computational and mathematical cardiovascular models use algorithms and equations to simulate the behavior of the cardiovascular system. These models may range from simple representations of a single heart chamber to complex simulations of the entire circulatory system. They can be used to study the electrical activity of the heart, the biomechanics of blood flow, or the distribution of drugs in the body.

Overall, cardiovascular models play an essential role in advancing our understanding of the human body and improving patient care.

The iliac arteries are major branches of the abdominal aorta, the large artery that carries oxygen-rich blood from the heart to the rest of the body. The iliac arteries divide into two branches, the common iliac arteries, which further bifurcate into the internal and external iliac arteries.

The internal iliac artery supplies blood to the lower abdomen, pelvis, and the reproductive organs, while the external iliac artery provides blood to the lower extremities, including the legs and feet. Together, the iliac arteries play a crucial role in circulating blood throughout the body, ensuring that all tissues and organs receive the oxygen and nutrients they need to function properly.

Blood volume refers to the total amount of blood present in an individual's circulatory system at any given time. It is the combined volume of both the plasma (the liquid component of blood) and the formed elements (such as red and white blood cells and platelets) in the blood. In a healthy adult human, the average blood volume is approximately 5 liters (or about 1 gallon). However, blood volume can vary depending on several factors, including age, sex, body weight, and overall health status.

Blood volume plays a critical role in maintaining proper cardiovascular function, as it affects blood pressure, heart rate, and the delivery of oxygen and nutrients to tissues throughout the body. Changes in blood volume can have significant impacts on an individual's health and may be associated with various medical conditions, such as dehydration, hemorrhage, heart failure, and liver disease. Accurate measurement of blood volume is essential for diagnosing and managing these conditions, as well as for guiding treatment decisions in clinical settings.

The renal artery is a pair of blood vessels that originate from the abdominal aorta and supply oxygenated blood to each kidney. These arteries branch into several smaller vessels that provide blood to the various parts of the kidneys, including the renal cortex and medulla. The renal arteries also carry nutrients and other essential components needed for the normal functioning of the kidneys. Any damage or blockage to the renal artery can lead to serious consequences, such as reduced kidney function or even kidney failure.

Ischemia is the medical term used to describe a lack of blood flow to a part of the body, often due to blocked or narrowed blood vessels. This can lead to a shortage of oxygen and nutrients in the tissues, which can cause them to become damaged or die. Ischemia can affect many different parts of the body, including the heart, brain, legs, and intestines. Symptoms of ischemia depend on the location and severity of the blockage, but they may include pain, cramping, numbness, weakness, or coldness in the affected area. In severe cases, ischemia can lead to tissue death (gangrene) or organ failure. Treatment for ischemia typically involves addressing the underlying cause of the blocked blood flow, such as through medication, surgery, or lifestyle changes.

Vasodilation is the widening or increase in diameter of blood vessels, particularly the involuntary relaxation of the smooth muscle in the tunica media (middle layer) of the arteriole walls. This results in an increase in blood flow and a decrease in vascular resistance. Vasodilation can occur due to various physiological and pathophysiological stimuli, such as local metabolic demands, neural signals, or pharmacological agents. It plays a crucial role in regulating blood pressure, tissue perfusion, and thermoregulation.

Pulmonary gas exchange is the process by which oxygen (O2) from inhaled air is transferred to the blood, and carbon dioxide (CO2), a waste product of metabolism, is removed from the blood and exhaled. This process occurs in the lungs, primarily in the alveoli, where the thin walls of the alveoli and capillaries allow for the rapid diffusion of gases between them. The partial pressure gradient between the alveolar air and the blood in the pulmonary capillaries drives this diffusion process. Oxygen-rich blood is then transported to the body's tissues, while CO2-rich blood returns to the lungs to be exhaled.

Vasodilator agents are pharmacological substances that cause the relaxation or widening of blood vessels by relaxing the smooth muscle in the vessel walls. This results in an increase in the diameter of the blood vessels, which decreases vascular resistance and ultimately reduces blood pressure. Vasodilators can be further classified based on their site of action:

1. Systemic vasodilators: These agents cause a generalized relaxation of the smooth muscle in the walls of both arteries and veins, resulting in a decrease in peripheral vascular resistance and preload (the volume of blood returning to the heart). Examples include nitroglycerin, hydralazine, and calcium channel blockers.
2. Arterial vasodilators: These agents primarily affect the smooth muscle in arterial vessel walls, leading to a reduction in afterload (the pressure against which the heart pumps blood). Examples include angiotensin-converting enzyme (ACE) inhibitors, angiotensin receptor blockers (ARBs), and direct vasodilators like sodium nitroprusside.
3. Venous vasodilators: These agents primarily affect the smooth muscle in venous vessel walls, increasing venous capacitance and reducing preload. Examples include nitroglycerin and other organic nitrates.

Vasodilator agents are used to treat various cardiovascular conditions such as hypertension, heart failure, angina, and pulmonary arterial hypertension. It is essential to monitor their use carefully, as excessive vasodilation can lead to orthostatic hypotension, reflex tachycardia, or fluid retention.

The supine position is a term used in medicine to describe a body posture where an individual is lying down on their back, with their face and torso facing upwards. This position is often adopted during various medical procedures, examinations, or when resting, as it allows for easy access to the front of the body. It is also the position automatically assumed by most people who are falling asleep.

It's important to note that in the supine position, the head can be flat on the surface or raised with the use of pillows or specialized medical equipment like a hospital bed. This can help to alleviate potential issues such as breathing difficulties or swelling in the face and head.

Inhalational anesthesia is a type of general anesthesia that is induced by the inhalation of gases or vapors. It is administered through a breathing system, which delivers the anesthetic agents to the patient via a face mask, laryngeal mask airway, or endotracheal tube.

The most commonly used inhalational anesthetics include nitrous oxide, sevoflurane, isoflurane, and desflurane. These agents work by depressing the central nervous system, causing a reversible loss of consciousness, amnesia, analgesia, and muscle relaxation.

The depth of anesthesia can be easily adjusted during the procedure by changing the concentration of the anesthetic agent. Once the procedure is complete, the anesthetic agents are eliminated from the body through exhalation, allowing for a rapid recovery.

Inhalational anesthesia is commonly used in a wide range of surgical procedures due to its ease of administration, quick onset and offset of action, and ability to rapidly adjust the depth of anesthesia. However, it requires careful monitoring and management by trained anesthesia providers to ensure patient safety and optimize outcomes.

In the field of medicine, "time factors" refer to the duration of symptoms or time elapsed since the onset of a medical condition, which can have significant implications for diagnosis and treatment. Understanding time factors is crucial in determining the progression of a disease, evaluating the effectiveness of treatments, and making critical decisions regarding patient care.

For example, in stroke management, "time is brain," meaning that rapid intervention within a specific time frame (usually within 4.5 hours) is essential to administering tissue plasminogen activator (tPA), a clot-busting drug that can minimize brain damage and improve patient outcomes. Similarly, in trauma care, the "golden hour" concept emphasizes the importance of providing definitive care within the first 60 minutes after injury to increase survival rates and reduce morbidity.

Time factors also play a role in monitoring the progression of chronic conditions like diabetes or heart disease, where regular follow-ups and assessments help determine appropriate treatment adjustments and prevent complications. In infectious diseases, time factors are crucial for initiating antibiotic therapy and identifying potential outbreaks to control their spread.

Overall, "time factors" encompass the significance of recognizing and acting promptly in various medical scenarios to optimize patient outcomes and provide effective care.

NG-Nitroarginine Methyl Ester (L-NAME) is not a medication, but rather a research chemical used in scientific studies. It is an inhibitor of nitric oxide synthase, an enzyme that synthesizes nitric oxide, a molecule involved in the relaxation of blood vessels.

Therefore, L-NAME is often used in experiments to investigate the role of nitric oxide in various physiological and pathophysiological processes. It is important to note that the use of L-NAME in humans is not approved for therapeutic purposes due to its potential side effects, which can include hypertension, decreased renal function, and decreased cerebral blood flow.

In medical terms, the heart is a muscular organ located in the thoracic cavity that functions as a pump to circulate blood throughout the body. It's responsible for delivering oxygen and nutrients to the tissues and removing carbon dioxide and other wastes. The human heart is divided into four chambers: two atria on the top and two ventricles on the bottom. The right side of the heart receives deoxygenated blood from the body and pumps it to the lungs, while the left side receives oxygenated blood from the lungs and pumps it out to the rest of the body. The heart's rhythmic contractions and relaxations are regulated by a complex electrical conduction system.

Collateral circulation refers to the alternate blood supply routes that bypass an obstructed or narrowed vessel and reconnect with the main vascular system. These collateral vessels can develop over time as a result of the body's natural adaptation to chronic ischemia (reduced blood flow) caused by various conditions such as atherosclerosis, thromboembolism, or vasculitis.

The development of collateral circulation helps maintain adequate blood flow and oxygenation to affected tissues, minimizing the risk of tissue damage and necrosis. In some cases, well-developed collateral circulations can help compensate for significant blockages in major vessels, reducing symptoms and potentially preventing the need for invasive interventions like revascularization procedures. However, the extent and effectiveness of collateral circulation vary from person to person and depend on factors such as age, overall health status, and the presence of comorbidities.

The myocardium is the middle layer of the heart wall, composed of specialized cardiac muscle cells that are responsible for pumping blood throughout the body. It forms the thickest part of the heart wall and is divided into two sections: the left ventricle, which pumps oxygenated blood to the rest of the body, and the right ventricle, which pumps deoxygenated blood to the lungs.

The myocardium contains several types of cells, including cardiac muscle fibers, connective tissue, nerves, and blood vessels. The muscle fibers are arranged in a highly organized pattern that allows them to contract in a coordinated manner, generating the force necessary to pump blood through the heart and circulatory system.

Damage to the myocardium can occur due to various factors such as ischemia (reduced blood flow), infection, inflammation, or genetic disorders. This damage can lead to several cardiac conditions, including heart failure, arrhythmias, and cardiomyopathy.

Isoflurane is a volatile halogenated ether used for induction and maintenance of general anesthesia. It is a colorless liquid with a pungent, sweet odor. Isoflurane is an agonist at the gamma-aminobutyric acid type A (GABAA) receptor and inhibits excitatory neurotransmission in the brain, leading to unconsciousness and immobility. It has a rapid onset and offset of action due to its low blood solubility, allowing for quick adjustments in anesthetic depth during surgery. Isoflurane is also known for its bronchodilator effects, making it useful in patients with reactive airway disease. However, it can cause dose-dependent decreases in heart rate and blood pressure, so careful hemodynamic monitoring is required during its use.

In medical terms, the leg refers to the lower portion of the human body that extends from the knee down to the foot. It includes the thigh (femur), lower leg (tibia and fibula), foot, and ankle. The leg is primarily responsible for supporting the body's weight and enabling movements such as standing, walking, running, and jumping.

The leg contains several important structures, including bones, muscles, tendons, ligaments, blood vessels, nerves, and joints. These structures work together to provide stability, support, and mobility to the lower extremity. Common medical conditions that can affect the leg include fractures, sprains, strains, infections, peripheral artery disease, and neurological disorders.

Parenteral infusions refer to the administration of fluids or medications directly into a patient's vein or subcutaneous tissue using a needle or catheter. This route bypasses the gastrointestinal tract and allows for rapid absorption and onset of action. Parenteral infusions can be used to correct fluid and electrolyte imbalances, administer medications that cannot be given orally, provide nutritional support, and deliver blood products. Common types of parenteral infusions include intravenous (IV) drips, IV push, and subcutaneous infusions. It is important that parenteral infusions are administered using aseptic technique to reduce the risk of infection.

Nitric oxide (NO) is a molecule made up of one nitrogen atom and one oxygen atom. In the body, it is a crucial signaling molecule involved in various physiological processes such as vasodilation, immune response, neurotransmission, and inhibition of platelet aggregation. It is produced naturally by the enzyme nitric oxide synthase (NOS) from the amino acid L-arginine. Inhaled nitric oxide is used medically to treat pulmonary hypertension in newborns and adults, as it helps to relax and widen blood vessels, improving oxygenation and blood flow.

The mesenteric arteries are the arteries that supply oxygenated blood to the intestines. There are three main mesenteric arteries: the superior mesenteric artery, which supplies blood to the small intestine (duodenum to two-thirds of the transverse colon) and large intestine (cecum, ascending colon, and the first part of the transverse colon); the inferior mesenteric artery, which supplies blood to the distal third of the transverse colon, descending colon, sigmoid colon, and rectum; and the middle colic artery, which is a branch of the superior mesenteric artery that supplies blood to the transverse colon. These arteries are important in maintaining adequate blood flow to the intestines to support digestion and absorption of nutrients.

"Cat" is a common name that refers to various species of small carnivorous mammals that belong to the family Felidae. The domestic cat, also known as Felis catus or Felis silvestris catus, is a popular pet and companion animal. It is a subspecies of the wildcat, which is found in Europe, Africa, and Asia.

Domestic cats are often kept as pets because of their companionship, playful behavior, and ability to hunt vermin. They are also valued for their ability to provide emotional support and therapy to people. Cats are obligate carnivores, which means that they require a diet that consists mainly of meat to meet their nutritional needs.

Cats are known for their agility, sharp senses, and predatory instincts. They have retractable claws, which they use for hunting and self-defense. Cats also have a keen sense of smell, hearing, and vision, which allow them to detect prey and navigate their environment.

In medical terms, cats can be hosts to various parasites and diseases that can affect humans and other animals. Some common feline diseases include rabies, feline leukemia virus (FeLV), feline immunodeficiency virus (FIV), and toxoplasmosis. It is important for cat owners to keep their pets healthy and up-to-date on vaccinations and preventative treatments to protect both the cats and their human companions.

Flow cytometry is a medical and research technique used to measure physical and chemical characteristics of cells or particles, one cell at a time, as they flow in a fluid stream through a beam of light. The properties measured include:

* Cell size (light scatter)
* Cell internal complexity (granularity, also light scatter)
* Presence or absence of specific proteins or other molecules on the cell surface or inside the cell (using fluorescent antibodies or other fluorescent probes)

The technique is widely used in cell counting, cell sorting, protein engineering, biomarker discovery and monitoring disease progression, particularly in hematology, immunology, and cancer research.

Sprague-Dawley rats are a strain of albino laboratory rats that are widely used in scientific research. They were first developed by researchers H.H. Sprague and R.C. Dawley in the early 20th century, and have since become one of the most commonly used rat strains in biomedical research due to their relatively large size, ease of handling, and consistent genetic background.

Sprague-Dawley rats are outbred, which means that they are genetically diverse and do not suffer from the same limitations as inbred strains, which can have reduced fertility and increased susceptibility to certain diseases. They are also characterized by their docile nature and low levels of aggression, making them easier to handle and study than some other rat strains.

These rats are used in a wide variety of research areas, including toxicology, pharmacology, nutrition, cancer, and behavioral studies. Because they are genetically diverse, Sprague-Dawley rats can be used to model a range of human diseases and conditions, making them an important tool in the development of new drugs and therapies.

Propranolol is a medication that belongs to a class of drugs called beta blockers. Medically, it is defined as a non-selective beta blocker, which means it blocks the effects of both epinephrine (adrenaline) and norepinephrine (noradrenaline) on the heart and other organs. These effects include reducing heart rate, contractility, and conduction velocity, leading to decreased oxygen demand by the myocardium. Propranolol is used in the management of various conditions such as hypertension, angina pectoris, arrhythmias, essential tremor, anxiety disorders, and infants with congenital heart defects. It may also be used to prevent migraines and reduce the risk of future heart attacks. As with any medication, it should be taken under the supervision of a healthcare provider due to potential side effects and contraindications.

Emission-Computed Tomography, Single-Photon (SPECT) is a type of nuclear medicine imaging procedure that generates detailed, three-dimensional images of the distribution of radioactive pharmaceuticals within the body. It uses gamma rays emitted by a radiopharmaceutical that is introduced into the patient's body, and a specialized gamma camera to detect these gamma rays and create tomographic images. The data obtained from the SPECT imaging can be used to diagnose various medical conditions, evaluate organ function, and guide treatment decisions. It is commonly used to image the heart, brain, and bones, among other organs and systems.

The forearm is the region of the upper limb between the elbow and the wrist. It consists of two bones, the radius and ulna, which are located side by side and run parallel to each other. The forearm is responsible for movements such as flexion, extension, supination, and pronation of the hand and wrist.

The sympathetic nervous system (SNS) is a part of the autonomic nervous system that operates largely below the level of consciousness, and it functions to produce appropriate physiological responses to perceived danger. It's often associated with the "fight or flight" response. The SNS uses nerve impulses to stimulate target organs, causing them to speed up (e.g., increased heart rate), prepare for action, or otherwise respond to stressful situations.

The sympathetic nervous system is activated due to stressful emotional or physical situations and it prepares the body for immediate actions. It dilates the pupils, increases heart rate and blood pressure, accelerates breathing, and slows down digestion. The primary neurotransmitter involved in this system is norepinephrine (also known as noradrenaline).

Skeletal muscle, also known as striated or voluntary muscle, is a type of muscle that is attached to bones by tendons or aponeuroses and functions to produce movements and support the posture of the body. It is composed of long, multinucleated fibers that are arranged in parallel bundles and are characterized by alternating light and dark bands, giving them a striped appearance under a microscope. Skeletal muscle is under voluntary control, meaning that it is consciously activated through signals from the nervous system. It is responsible for activities such as walking, running, jumping, and lifting objects.

I apologize, but "sheep" is not a term that has a medical definition. It is a common animal with the scientific name Ovis aries. If you have any medical or health-related questions, I would be happy to try and help answer those for you.

Norepinephrine, also known as noradrenaline, is a neurotransmitter and a hormone that is primarily produced in the adrenal glands and is released into the bloodstream in response to stress or physical activity. It plays a crucial role in the "fight-or-flight" response by preparing the body for action through increasing heart rate, blood pressure, respiratory rate, and glucose availability.

As a neurotransmitter, norepinephrine is involved in regulating various functions of the nervous system, including attention, perception, motivation, and arousal. It also plays a role in modulating pain perception and responding to stressful or emotional situations.

In medical settings, norepinephrine is used as a vasopressor medication to treat hypotension (low blood pressure) that can occur during septic shock, anesthesia, or other critical illnesses. It works by constricting blood vessels and increasing heart rate, which helps to improve blood pressure and perfusion of vital organs.

"Wistar rats" are a strain of albino rats that are widely used in laboratory research. They were developed at the Wistar Institute in Philadelphia, USA, and were first introduced in 1906. Wistar rats are outbred, which means that they are genetically diverse and do not have a fixed set of genetic characteristics like inbred strains.

Wistar rats are commonly used as animal models in biomedical research because of their size, ease of handling, and relatively low cost. They are used in a wide range of research areas, including toxicology, pharmacology, nutrition, cancer, cardiovascular disease, and behavioral studies. Wistar rats are also used in safety testing of drugs, medical devices, and other products.

Wistar rats are typically larger than many other rat strains, with males weighing between 500-700 grams and females weighing between 250-350 grams. They have a lifespan of approximately 2-3 years. Wistar rats are also known for their docile and friendly nature, making them easy to handle and work with in the laboratory setting.

"Inbred strains of rats" are genetically identical rodents that have been produced through many generations of brother-sister mating. This results in a high degree of homozygosity, where the genes at any particular locus in the genome are identical in all members of the strain.

Inbred strains of rats are widely used in biomedical research because they provide a consistent and reproducible genetic background for studying various biological phenomena, including the effects of drugs, environmental factors, and genetic mutations on health and disease. Additionally, inbred strains can be used to create genetically modified models of human diseases by introducing specific mutations into their genomes.

Some commonly used inbred strains of rats include the Wistar Kyoto (WKY), Sprague-Dawley (SD), and Fischer 344 (F344) rat strains. Each strain has its own unique genetic characteristics, making them suitable for different types of research.

Intravenous injections are a type of medical procedure where medication or fluids are administered directly into a vein using a needle and syringe. This route of administration is also known as an IV injection. The solution injected enters the patient's bloodstream immediately, allowing for rapid absorption and onset of action. Intravenous injections are commonly used to provide quick relief from symptoms, deliver medications that are not easily absorbed by other routes, or administer fluids and electrolytes in cases of dehydration or severe illness. It is important that intravenous injections are performed using aseptic technique to minimize the risk of infection.

Nitric Oxide Synthase (NOS) is a group of enzymes that catalyze the production of nitric oxide (NO) from L-arginine. There are three distinct isoforms of NOS, each with different expression patterns and functions:

1. Neuronal Nitric Oxide Synthase (nNOS or NOS1): This isoform is primarily expressed in the nervous system and plays a role in neurotransmission, synaptic plasticity, and learning and memory processes.
2. Inducible Nitric Oxide Synthase (iNOS or NOS2): This isoform is induced by various stimuli such as cytokines, lipopolysaccharides, and hypoxia in a variety of cells including immune cells, endothelial cells, and smooth muscle cells. iNOS produces large amounts of NO, which functions as a potent effector molecule in the immune response, particularly in the defense against microbial pathogens.
3. Endothelial Nitric Oxide Synthase (eNOS or NOS3): This isoform is constitutively expressed in endothelial cells and produces low levels of NO that play a crucial role in maintaining vascular homeostasis by regulating vasodilation, inhibiting platelet aggregation, and preventing smooth muscle cell proliferation.

Overall, NOS plays an essential role in various physiological processes, including neurotransmission, immune response, cardiovascular function, and respiratory regulation. Dysregulation of NOS activity has been implicated in several pathological conditions such as hypertension, atherosclerosis, neurodegenerative diseases, and inflammatory disorders.

Pulsatile flow is a type of fluid flow that occurs in a rhythmic, wave-like pattern, typically seen in the cardiovascular system. It refers to the periodic variation in the volume or velocity of a fluid (such as blood) that is caused by the regular beating of the heart. In pulsatile flow, there are periods of high flow followed by periods of low or no flow, which creates a distinct pattern on a graph or tracing. This type of flow is important for maintaining proper function and health in organs and tissues throughout the body.

I believe there may be some confusion in your question. "Rabbits" is a common name used to refer to the Lagomorpha species, particularly members of the family Leporidae. They are small mammals known for their long ears, strong legs, and quick reproduction.

However, if you're referring to "rabbits" in a medical context, there is a term called "rabbit syndrome," which is a rare movement disorder characterized by repetitive, involuntary movements of the fingers, resembling those of a rabbit chewing. It is also known as "finger-chewing chorea." This condition is usually associated with certain medications, particularly antipsychotics, and typically resolves when the medication is stopped or adjusted.

A dose-response relationship in the context of drugs refers to the changes in the effects or symptoms that occur as the dose of a drug is increased or decreased. Generally, as the dose of a drug is increased, the severity or intensity of its effects also increases. Conversely, as the dose is decreased, the effects of the drug become less severe or may disappear altogether.

The dose-response relationship is an important concept in pharmacology and toxicology because it helps to establish the safe and effective dosage range for a drug. By understanding how changes in the dose of a drug affect its therapeutic and adverse effects, healthcare providers can optimize treatment plans for their patients while minimizing the risk of harm.

The dose-response relationship is typically depicted as a curve that shows the relationship between the dose of a drug and its effect. The shape of the curve may vary depending on the drug and the specific effect being measured. Some drugs may have a steep dose-response curve, meaning that small changes in the dose can result in large differences in the effect. Other drugs may have a more gradual dose-response curve, where larger changes in the dose are needed to produce significant effects.

In addition to helping establish safe and effective dosages, the dose-response relationship is also used to evaluate the potential therapeutic benefits and risks of new drugs during clinical trials. By systematically testing different doses of a drug in controlled studies, researchers can identify the optimal dosage range for the drug and assess its safety and efficacy.

Coronary vessels refer to the network of blood vessels that supply oxygenated blood and nutrients to the heart muscle, also known as the myocardium. The two main coronary arteries are the left main coronary artery and the right coronary artery.

The left main coronary artery branches off into the left anterior descending artery (LAD) and the left circumflex artery (LCx). The LAD supplies blood to the front of the heart, while the LCx supplies blood to the side and back of the heart.

The right coronary artery supplies blood to the right lower part of the heart, including the right atrium and ventricle, as well as the back of the heart.

Coronary vessel disease (CVD) occurs when these vessels become narrowed or blocked due to the buildup of plaque, leading to reduced blood flow to the heart muscle. This can result in chest pain, shortness of breath, or a heart attack.

Animal disease models are specialized animals, typically rodents such as mice or rats, that have been genetically engineered or exposed to certain conditions to develop symptoms and physiological changes similar to those seen in human diseases. These models are used in medical research to study the pathophysiology of diseases, identify potential therapeutic targets, test drug efficacy and safety, and understand disease mechanisms.

The genetic modifications can include knockout or knock-in mutations, transgenic expression of specific genes, or RNA interference techniques. The animals may also be exposed to environmental factors such as chemicals, radiation, or infectious agents to induce the disease state.

Examples of animal disease models include:

1. Mouse models of cancer: Genetically engineered mice that develop various types of tumors, allowing researchers to study cancer initiation, progression, and metastasis.
2. Alzheimer's disease models: Transgenic mice expressing mutant human genes associated with Alzheimer's disease, which exhibit amyloid plaque formation and cognitive decline.
3. Diabetes models: Obese and diabetic mouse strains like the NOD (non-obese diabetic) or db/db mice, used to study the development of type 1 and type 2 diabetes, respectively.
4. Cardiovascular disease models: Atherosclerosis-prone mice, such as ApoE-deficient or LDLR-deficient mice, that develop plaque buildup in their arteries when fed a high-fat diet.
5. Inflammatory bowel disease models: Mice with genetic mutations affecting intestinal barrier function and immune response, such as IL-10 knockout or SAMP1/YitFc mice, which develop colitis.

Animal disease models are essential tools in preclinical research, but it is important to recognize their limitations. Differences between species can affect the translatability of results from animal studies to human patients. Therefore, researchers must carefully consider the choice of model and interpret findings cautiously when applying them to human diseases.

Medical Definition:

Magnetic Resonance Imaging (MRI) is a non-invasive diagnostic imaging technique that uses a strong magnetic field and radio waves to create detailed cross-sectional or three-dimensional images of the internal structures of the body. The patient lies within a large, cylindrical magnet, and the scanner detects changes in the direction of the magnetic field caused by protons in the body. These changes are then converted into detailed images that help medical professionals to diagnose and monitor various medical conditions, such as tumors, injuries, or diseases affecting the brain, spinal cord, heart, blood vessels, joints, and other internal organs. MRI does not use radiation like computed tomography (CT) scans.

Reference values, also known as reference ranges or reference intervals, are the set of values that are considered normal or typical for a particular population or group of people. These values are often used in laboratory tests to help interpret test results and determine whether a patient's value falls within the expected range.

The process of establishing reference values typically involves measuring a particular biomarker or parameter in a large, healthy population and then calculating the mean and standard deviation of the measurements. Based on these statistics, a range is established that includes a certain percentage of the population (often 95%) and excludes extreme outliers.

It's important to note that reference values can vary depending on factors such as age, sex, race, and other demographic characteristics. Therefore, it's essential to use reference values that are specific to the relevant population when interpreting laboratory test results. Additionally, reference values may change over time due to advances in measurement technology or changes in the population being studied.

Arteries are blood vessels that carry oxygenated blood away from the heart to the rest of the body. They have thick, muscular walls that can withstand the high pressure of blood being pumped out of the heart. Arteries branch off into smaller vessels called arterioles, which further divide into a vast network of tiny capillaries where the exchange of oxygen, nutrients, and waste occurs between the blood and the body's cells. After passing through the capillary network, deoxygenated blood collects in venules, then merges into veins, which return the blood back to the heart.

A lung is a pair of spongy, elastic organs in the chest that work together to enable breathing. They are responsible for taking in oxygen and expelling carbon dioxide through the process of respiration. The left lung has two lobes, while the right lung has three lobes. The lungs are protected by the ribcage and are covered by a double-layered membrane called the pleura. The trachea divides into two bronchi, which further divide into smaller bronchioles, leading to millions of tiny air sacs called alveoli, where the exchange of gases occurs.

Myocardial contraction refers to the rhythmic and forceful shortening of heart muscle cells (myocytes) in the myocardium, which is the muscular wall of the heart. This process is initiated by electrical signals generated by the sinoatrial node, causing a wave of depolarization that spreads throughout the heart.

During myocardial contraction, calcium ions flow into the myocytes, triggering the interaction between actin and myosin filaments, which are the contractile proteins in the muscle cells. This interaction causes the myofilaments to slide past each other, resulting in the shortening of the sarcomeres (the functional units of muscle contraction) and ultimately leading to the contraction of the heart muscle.

Myocardial contraction is essential for pumping blood throughout the body and maintaining adequate circulation to vital organs. Any impairment in myocardial contractility can lead to various cardiac disorders, such as heart failure, cardiomyopathy, and arrhythmias.

Capillaries are the smallest blood vessels in the body, with diameters that range from 5 to 10 micrometers. They form a network of tiny tubes that connect the arterioles (small branches of arteries) and venules (small branches of veins), allowing for the exchange of oxygen, carbon dioxide, nutrients, and waste products between the blood and the surrounding tissues.

Capillaries are composed of a single layer of endothelial cells that surround a hollow lumen through which blood flows. The walls of capillaries are extremely thin, allowing for easy diffusion of molecules between the blood and the surrounding tissue. This is essential for maintaining the health and function of all body tissues.

Capillaries can be classified into three types based on their structure and function: continuous, fenestrated, and sinusoidal. Continuous capillaries have a continuous layer of endothelial cells with tight junctions that restrict the passage of large molecules. Fenestrated capillaries have small pores or "fenestrae" in the endothelial cell walls that allow for the passage of larger molecules, such as proteins and lipids. Sinusoidal capillaries are found in organs with high metabolic activity, such as the liver and spleen, and have large, irregular spaces between the endothelial cells that allow for the exchange of even larger molecules.

Overall, capillaries play a critical role in maintaining the health and function of all body tissues by allowing for the exchange of nutrients, oxygen, and waste products between the blood and surrounding tissues.

A blood donor is a person who voluntarily gives their own blood or blood components to be used for the benefit of another person in need. The blood donation process involves collecting the donor's blood, testing it for infectious diseases, and then storing it until it is needed by a patient. There are several types of blood donations, including:

1. Whole blood donation: This is the most common type of blood donation, where a donor gives one unit (about 450-500 milliliters) of whole blood. The blood is then separated into its components (red cells, plasma, and platelets) for transfusion to patients with different needs.
2. Double red cell donation: In this type of donation, the donor's blood is collected using a special machine that separates two units of red cells from the whole blood. The remaining plasma and platelets are returned to the donor during the donation process. This type of donation can be done every 112 days.
3. Platelet donation: A donor's blood is collected using a special machine that separates platelets from the whole blood. The red cells and plasma are then returned to the donor during the donation process. This type of donation can be done every seven days, up to 24 times a year.
4. Plasma donation: A donor's blood is collected using a special machine that separates plasma from the whole blood. The red cells and platelets are then returned to the donor during the donation process. This type of donation can be done every 28 days, up to 13 times a year.

Blood donors must meet certain eligibility criteria, such as being in good health, aged between 18 and 65 (in some countries, the upper age limit may vary), and weighing over 50 kg (110 lbs). Donors are also required to answer medical questionnaires and undergo a mini-physical examination before each donation. The frequency of blood donations varies depending on the type of donation and the donor's health status.

Enzyme inhibitors are substances that bind to an enzyme and decrease its activity, preventing it from catalyzing a chemical reaction in the body. They can work by several mechanisms, including blocking the active site where the substrate binds, or binding to another site on the enzyme to change its shape and prevent substrate binding. Enzyme inhibitors are often used as drugs to treat various medical conditions, such as high blood pressure, abnormal heart rhythms, and bacterial infections. They can also be found naturally in some foods and plants, and can be used in research to understand enzyme function and regulation.

Myocardial infarction (MI), also known as a heart attack, is a medical condition characterized by the death of a segment of heart muscle (myocardium) due to the interruption of its blood supply. This interruption is most commonly caused by the blockage of a coronary artery by a blood clot formed on the top of an atherosclerotic plaque, which is a buildup of cholesterol and other substances in the inner lining of the artery.

The lack of oxygen and nutrients supply to the heart muscle tissue results in damage or death of the cardiac cells, causing the affected area to become necrotic. The extent and severity of the MI depend on the size of the affected area, the duration of the occlusion, and the presence of collateral circulation.

Symptoms of a myocardial infarction may include chest pain or discomfort, shortness of breath, nausea, lightheadedness, and sweating. Immediate medical attention is necessary to restore blood flow to the affected area and prevent further damage to the heart muscle. Treatment options for MI include medications, such as thrombolytics, antiplatelet agents, and pain relievers, as well as procedures such as percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG).

Coronary artery disease, often simply referred to as coronary disease, is a condition in which the blood vessels that supply oxygen-rich blood to the heart become narrowed or blocked due to the buildup of fatty deposits called plaques. This can lead to chest pain (angina), shortness of breath, or in severe cases, a heart attack.

The medical definition of coronary artery disease is:

A condition characterized by the accumulation of atheromatous plaques in the walls of the coronary arteries, leading to decreased blood flow and oxygen supply to the myocardium (heart muscle). This can result in symptoms such as angina pectoris, shortness of breath, or arrhythmias, and may ultimately lead to myocardial infarction (heart attack) or heart failure.

Risk factors for coronary artery disease include age, smoking, high blood pressure, high cholesterol, diabetes, obesity, physical inactivity, and a family history of the condition. Lifestyle changes such as quitting smoking, exercising regularly, eating a healthy diet, and managing stress can help reduce the risk of developing coronary artery disease. Medical treatments may include medications to control blood pressure, cholesterol levels, or irregular heart rhythms, as well as procedures such as angioplasty or bypass surgery to improve blood flow to the heart.

Rheology is not a term that is specific to medicine, but rather it is a term used in the field of physics to describe the flow and deformation of matter. It specifically refers to the study of how materials flow or deform under various stresses or strains. This concept can be applied to various medical fields such as studying the flow properties of blood (hematology), understanding the movement of tissues and organs during surgical procedures, or analyzing the mechanical behavior of biological materials like bones and cartilages.

Anoxia is a medical condition that refers to the absence or complete lack of oxygen supply in the body or a specific organ, tissue, or cell. This can lead to serious health consequences, including damage or death of cells and tissues, due to the vital role that oxygen plays in supporting cellular metabolism and energy production.

Anoxia can occur due to various reasons, such as respiratory failure, cardiac arrest, severe blood loss, carbon monoxide poisoning, or high altitude exposure. Prolonged anoxia can result in hypoxic-ischemic encephalopathy, a serious condition that can cause brain damage and long-term neurological impairments.

Medical professionals use various diagnostic tests, such as blood gas analysis, pulse oximetry, and electroencephalography (EEG), to assess oxygen levels in the body and diagnose anoxia. Treatment for anoxia typically involves addressing the underlying cause, providing supplemental oxygen, and supporting vital functions, such as breathing and circulation, to prevent further damage.

Hyperemia is a medical term that refers to an increased flow or accumulation of blood in certain capillaries or vessels within an organ or tissue, resulting in its redness and warmth. This can occur due to various reasons such as physical exertion, emotional excitement, local injury, or specific medical conditions.

There are two types of hyperemia: active and passive. Active hyperemia is a physiological response where the blood flow increases as a result of the metabolic demands of the organ or tissue. For example, during exercise, muscles require more oxygen and nutrients, leading to an increase in blood flow. Passive hyperemia, on the other hand, occurs when there is a blockage in the venous outflow, causing the blood to accumulate in the affected area. This can result from conditions like thrombosis or vasoconstriction.

It's important to note that while hyperemia itself is not a disease, it can be a symptom of various underlying medical conditions and should be evaluated by a healthcare professional if it persists or is accompanied by other symptoms.

Ultrasonography, Doppler refers to a non-invasive diagnostic medical procedure that uses high-frequency sound waves to create real-time images of the movement of blood flow through vessels, tissues, or heart valves. The Doppler effect is used to measure the frequency shift of the ultrasound waves as they bounce off moving red blood cells, which allows for the calculation of the speed and direction of blood flow. This technique is commonly used to diagnose and monitor various conditions such as deep vein thrombosis, carotid artery stenosis, heart valve abnormalities, and fetal heart development during pregnancy. It does not use radiation or contrast agents and is considered safe with minimal risks.

Xenon is a noble gas with symbol Xe and atomic number 54. It's a colorless, heavy, odorless, and chemically inert gas. In the field of medicine, xenon has been used as a general anesthetic due to its ability to produce unconsciousness while preserving physiological reflexes and cardiovascular stability. Its use is limited due to high cost compared to other anesthetics.

Gene flow, also known as genetic migration or gene admixture, refers to the transfer of genetic variation from one population to another. It occurs when individuals reproduce and exchange genes with members of other populations through processes such as migration and interbreeding. This can result in an alteration of the genetic composition of both populations, increasing genetic diversity and reducing the differences between them. Gene flow is an important mechanism in evolutionary biology and population genetics, contributing to the distribution and frequency of alleles (versions of a gene) within and across populations.

Blood circulation time is the duration it takes for blood to travel throughout the body and return to the point of origin. It is typically measured from the time a substance is injected into the bloodstream until it can be detected at the original injection site after circulating through the body. This measurement can provide valuable information about an individual's cardiovascular health, as any delays in circulation time may indicate issues with the heart or blood vessels.

In medical terms, blood circulation time is often divided into two components: the pulmonary circulation time and the systemic circulation time. The pulmonary circulation time refers to the time it takes for blood to travel from the heart to the lungs and back again, while the systemic circulation time refers to the time it takes for blood to travel from the heart to the rest of the body and back again.

There are several methods for measuring blood circulation time, including injecting a dye or other substance into the bloodstream and using specialized equipment to detect its presence at various points in the body. This information can be used to diagnose and monitor conditions such as heart disease, shock, and other circulatory disorders.

Ultrasonography, Doppler, color is a type of diagnostic ultrasound technique that uses the Doppler effect to produce visual images of blood flow in vessels and the heart. The Doppler effect is the change in frequency or wavelength of a wave in relation to an observer who is moving relative to the source of the wave. In this context, it refers to the change in frequency of the ultrasound waves as they reflect off moving red blood cells.

In color Doppler ultrasonography, different colors are used to represent the direction and speed of blood flow. Red typically represents blood flowing toward the transducer (the device that sends and receives sound waves), while blue represents blood flowing away from the transducer. The intensity or brightness of the color is proportional to the velocity of blood flow.

Color Doppler ultrasonography is often used in conjunction with grayscale ultrasound imaging, which provides information about the structure and composition of tissues. Together, these techniques can help diagnose a wide range of conditions, including heart disease, blood clots, and abnormalities in blood flow.

Plethysmography is a non-invasive medical technique used to measure changes in volume or blood flow within an organ or body part, typically in the lungs or extremities. There are several types of plethysmography, including:

1. **Whole Body Plethysmography (WBP):** This type of plethysmography is used to assess lung function and volumes by measuring changes in pressure within a sealed chamber that contains the patient's entire body except for their head. The patient breathes normally while wearing a nose clip, allowing technicians to analyze respiratory patterns, airflow, and lung volume changes.
2. **Segmental or Local Plethysmography:** This technique measures volume or blood flow changes in specific body parts, such as the limbs or digits. It can help diagnose and monitor conditions affecting peripheral circulation, like deep vein thrombosis, arterial occlusive disease, or Raynaud's phenomenon.
3. **Impedance Plethysmography (IPG):** This non-invasive method uses electrical impedance to estimate changes in blood volume within an organ or body part. By applying a small electrical current and measuring the opposition to flow (impedance), technicians can determine variations in blood volume, which can help diagnose conditions like deep vein thrombosis or heart failure.
4. **Optical Plethysmography:** This technique uses light to measure changes in blood volume, typically in the skin or mucous membranes. By shining a light on the area and analyzing the reflected or transmitted light, technicians can detect variations in blood volume related to cardiac output, respiration, or other physiological factors.

Overall, plethysmography is an essential tool for diagnosing and monitoring various medical conditions affecting circulation, respiratory function, and organ volumes.

Posture is the position or alignment of body parts supported by the muscles, especially the spine and head in relation to the vertebral column. It can be described as static (related to a stationary position) or dynamic (related to movement). Good posture involves training your body to stand, walk, sit, and lie in positions where the least strain is placed on supporting muscles and ligaments during movement or weight-bearing activities. Poor posture can lead to various health issues such as back pain, neck pain, headaches, and respiratory problems.

Cerebral arteries refer to the blood vessels that supply oxygenated blood to the brain. These arteries branch off from the internal carotid arteries and the vertebral arteries, which combine to form the basilar artery. The major cerebral arteries include:

1. Anterior cerebral artery (ACA): This artery supplies blood to the frontal lobes of the brain, including the motor and sensory cortices responsible for movement and sensation in the lower limbs.
2. Middle cerebral artery (MCA): The MCA is the largest of the cerebral arteries and supplies blood to the lateral surface of the brain, including the temporal, parietal, and frontal lobes. It is responsible for providing blood to areas involved in motor function, sensory perception, speech, memory, and vision.
3. Posterior cerebral artery (PCA): The PCA supplies blood to the occipital lobe, which is responsible for visual processing, as well as parts of the temporal and parietal lobes.
4. Anterior communicating artery (ACoA) and posterior communicating arteries (PComAs): These are small arteries that connect the major cerebral arteries, forming an important circulatory network called the Circle of Willis. The ACoA connects the two ACAs, while the PComAs connect the ICA with the PCA and the basilar artery.

These cerebral arteries play a crucial role in maintaining proper brain function by delivering oxygenated blood to various regions of the brain. Any damage or obstruction to these arteries can lead to serious neurological conditions, such as strokes or transient ischemic attacks (TIAs).

Contrast media are substances that are administered to a patient in order to improve the visibility of internal body structures or processes in medical imaging techniques such as X-rays, CT scans, MRI scans, and ultrasounds. These media can be introduced into the body through various routes, including oral, rectal, or intravenous administration.

Contrast media work by altering the appearance of bodily structures in imaging studies. For example, when a patient undergoes an X-ray examination, contrast media can be used to highlight specific organs, tissues, or blood vessels, making them more visible on the resulting images. In CT and MRI scans, contrast media can help to enhance the differences between normal and abnormal tissues, allowing for more accurate diagnosis and treatment planning.

There are several types of contrast media available, each with its own specific properties and uses. Some common examples include barium sulfate, which is used as a contrast medium in X-ray studies of the gastrointestinal tract, and iodinated contrast media, which are commonly used in CT scans to highlight blood vessels and other structures.

While contrast media are generally considered safe, they can sometimes cause adverse reactions, ranging from mild symptoms such as nausea or hives to more serious complications such as anaphylaxis or kidney damage. As a result, it is important for healthcare providers to carefully evaluate each patient's medical history and individual risk factors before administering contrast media.

Transcranial Doppler ultrasonography is a non-invasive diagnostic technique that uses high-frequency sound waves to visualize and measure the velocity of blood flow in the cerebral arteries located in the skull. This imaging modality employs the Doppler effect, which describes the change in frequency of sound waves as they reflect off moving red blood cells. By measuring the frequency shift of the reflected ultrasound waves, the velocity and direction of blood flow can be determined.

Transcranial Doppler ultrasonography is primarily used to assess cerebrovascular circulation and detect abnormalities such as stenosis (narrowing), occlusion (blockage), or embolism (obstruction) in the intracranial arteries. It can also help monitor patients with conditions like sickle cell disease, vasospasm following subarachnoid hemorrhage, and evaluate the effectiveness of treatments such as thrombolysis or angioplasty. The procedure is typically performed by placing a transducer on the patient's skull after applying a coupling gel, and it does not involve radiation exposure or contrast agents.

Adrenergic beta-antagonists, also known as beta blockers, are a class of medications that block the effects of adrenaline and noradrenaline (also known as epinephrine and norepinephrine) on beta-adrenergic receptors. These receptors are found in various tissues throughout the body, including the heart, lungs, and blood vessels.

Beta blockers work by binding to these receptors and preventing the activation of certain signaling pathways that lead to increased heart rate, force of heart contractions, and relaxation of blood vessels. As a result, beta blockers can lower blood pressure, reduce heart rate, and decrease the workload on the heart.

Beta blockers are used to treat a variety of medical conditions, including hypertension (high blood pressure), angina (chest pain), heart failure, irregular heart rhythms, migraines, and certain anxiety disorders. Some common examples of beta blockers include metoprolol, atenolol, propranolol, and bisoprolol.

It is important to note that while beta blockers can have many benefits, they can also cause side effects such as fatigue, dizziness, and shortness of breath. Additionally, sudden discontinuation of beta blocker therapy can lead to rebound hypertension or worsening chest pain. Therefore, it is important to follow the dosing instructions provided by a healthcare provider carefully when taking these medications.

The Middle Cerebral Artery (MCA) is one of the main blood vessels that supplies oxygenated blood to the brain. It arises from the internal carotid artery and divides into several branches, which supply the lateral surface of the cerebral hemisphere, including the frontal, parietal, and temporal lobes.

The MCA is responsible for providing blood flow to critical areas of the brain, such as the primary motor and sensory cortices, Broca's area (associated with speech production), Wernicke's area (associated with language comprehension), and the visual association cortex.

Damage to the MCA or its branches can result in a variety of neurological deficits, depending on the specific location and extent of the injury. These may include weakness or paralysis on one side of the body, sensory loss, language impairment, and visual field cuts.

Retinal vessels refer to the blood vessels that are located in the retina, which is the light-sensitive tissue that lines the inner surface of the eye. The retina contains two types of blood vessels: arteries and veins.

The central retinal artery supplies oxygenated blood to the inner layers of the retina, while the central retinal vein drains deoxygenated blood from the retina. These vessels can be visualized during a routine eye examination using an ophthalmoscope, which allows healthcare professionals to assess their health and any potential abnormalities.

Retinal vessels are essential for maintaining the health and function of the retina, and any damage or changes to these vessels can affect vision and lead to various eye conditions such as diabetic retinopathy, retinal vein occlusion, and hypertensive retinopathy.

Antipyrine is a chemical compound that was commonly used as a fever reducer and pain reliever in the past. It is a type of phenylpyrazole antipyretic and analgesic. However, due to its potential for causing liver damage and other side effects, it has largely been replaced by other medications and is not widely used in modern medicine.

The medical definition of Antipyrine refers to this specific chemical compound with the formula C11H13N3O2, and not to any broader category of drugs or substances. It is a white crystalline powder that is soluble in alcohol, chloroform, and ether, but insoluble in water.

Antipyrine was first synthesized in 1883 and was widely used as a fever reducer and pain reliever until the mid-20th century. However, its use declined due to concerns about its safety profile, including the potential for liver damage, skin reactions, and other side effects.

Today, Antipyrine is still used in some medical applications, such as in the measurement of earwax conductivity as a way to assess hearing function. It may also be used in some topical creams and ointments for pain relief. However, its use as a systemic medication is generally not recommended due to its potential for causing harm.

Perfusion, in medical terms, refers to the process of circulating blood through the body's organs and tissues to deliver oxygen and nutrients and remove waste products. It is a measure of the delivery of adequate blood flow to specific areas or tissues in the body. Perfusion can be assessed using various methods, including imaging techniques like computed tomography (CT) scans, magnetic resonance imaging (MRI), and perfusion scintigraphy.

Perfusion is critical for maintaining proper organ function and overall health. When perfusion is impaired or inadequate, it can lead to tissue hypoxia, acidosis, and cell death, which can result in organ dysfunction or failure. Conditions that can affect perfusion include cardiovascular disease, shock, trauma, and certain surgical procedures.

The choroid is a layer of the eye that contains blood vessels that supply oxygen and nutrients to the outer layers of the retina. It lies between the sclera (the white, protective coat of the eye) and the retina (the light-sensitive tissue at the back of the eye). The choroid is essential for maintaining the health and function of the retina, particularly the photoreceptor cells that detect light and transmit visual signals to the brain. Damage to the choroid can lead to vision loss or impairment.

Skin temperature is the measure of heat emitted by the skin, which can be an indicator of the body's core temperature. It is typically lower than the body's internal temperature and varies depending on factors such as environmental temperature, blood flow, and physical activity. Skin temperature is often used as a vital sign in medical settings and can be measured using various methods, including thermal scanners, digital thermometers, or mercury thermometers. Changes in skin temperature may also be associated with certain medical conditions, such as inflammation, infection, or nerve damage.

The vasomotor system is a part of the autonomic nervous system that controls the diameter of blood vessels, particularly the smooth muscle in the walls of arterioles and precapillary sphincters. It regulates blood flow to different parts of the body by constricting or dilating these vessels. The vasomotor center located in the medulla oblongata of the brainstem controls the system, receiving input from various sensory receptors and modulating the sympathetic and parasympathetic nervous systems' activity. Vasoconstriction decreases blood flow, while vasodilation increases it.

The femoral artery is the major blood vessel that supplies oxygenated blood to the lower extremity of the human body. It is a continuation of the external iliac artery and becomes the popliteal artery as it passes through the adductor hiatus in the adductor magnus muscle of the thigh.

The femoral artery is located in the femoral triangle, which is bound by the sartorius muscle anteriorly, the adductor longus muscle medially, and the biceps femoris muscle posteriorly. It can be easily palpated in the groin region, making it a common site for taking blood samples, measuring blood pressure, and performing surgical procedures such as femoral artery catheterization and bypass grafting.

The femoral artery gives off several branches that supply blood to the lower limb, including the deep femoral artery, the superficial femoral artery, and the profunda femoris artery. These branches provide blood to the muscles, bones, skin, and other tissues of the leg, ankle, and foot.

Brain ischemia is the medical term used to describe a reduction or interruption of blood flow to the brain, leading to a lack of oxygen and glucose delivery to brain tissue. This can result in brain damage or death of brain cells, known as infarction. Brain ischemia can be caused by various conditions such as thrombosis (blood clot formation), embolism (obstruction of a blood vessel by a foreign material), or hypoperfusion (reduced blood flow). The severity and duration of the ischemia determine the extent of brain damage. Symptoms can range from mild, such as transient ischemic attacks (TIAs or "mini-strokes"), to severe, including paralysis, speech difficulties, loss of consciousness, and even death. Immediate medical attention is required for proper diagnosis and treatment to prevent further damage and potential long-term complications.

In medical terms, the skin is the largest organ of the human body. It consists of two main layers: the epidermis (outer layer) and dermis (inner layer), as well as accessory structures like hair follicles, sweat glands, and oil glands. The skin plays a crucial role in protecting us from external factors such as bacteria, viruses, and environmental hazards, while also regulating body temperature and enabling the sense of touch.

Adenosine is a purine nucleoside that is composed of a sugar (ribose) and the base adenine. It plays several important roles in the body, including serving as a precursor for the synthesis of other molecules such as ATP, NAD+, and RNA.

In the medical context, adenosine is perhaps best known for its use as a pharmaceutical agent to treat certain cardiac arrhythmias. When administered intravenously, it can help restore normal sinus rhythm in patients with paroxysmal supraventricular tachycardia (PSVT) by slowing conduction through the atrioventricular node and interrupting the reentry circuit responsible for the arrhythmia.

Adenosine can also be used as a diagnostic tool to help differentiate between narrow-complex tachycardias of supraventricular origin and those that originate from below the ventricles (such as ventricular tachycardia). This is because adenosine will typically terminate PSVT but not affect the rhythm of VT.

It's worth noting that adenosine has a very short half-life, lasting only a few seconds in the bloodstream. This means that its effects are rapidly reversible and generally well-tolerated, although some patients may experience transient symptoms such as flushing, chest pain, or shortness of breath.

Blood Flow Metab. 13 (3): 526-30. doi:10.1038/jcbfm.1993.68. PMID 8478410. "Launch of tablet to make life easier for dogs in ... Huber M, Kittner B, Hojer C, Fink GR, Neveling M, Heiss WD (1993). "Effect of propentofylline on regional cerebral glucose ...
In 1965, the first regional Cerebral Blood Flow (rCBF) symposium was held in Lund, Sweden. In March 1980, following discussions ... "History of International Society for Cerebral Blood Flow and Metabolism" (PDF). Journal of Cerebral Blood Flow & Metabolism. 32 ... Technical improvements in the study of cerebral blood flow pioneered by Niels Lassen and David Ingvar in the mid-twentieth ... The Journal of Cerebral Blood Flow & Metabolism has been an important element of the ISCFBM since the organization's founding. ...
Journal of Cerebral Blood Flow and Metabolism. 15 (4): 681-6. doi:10.1038/jcbfm.1995.85. PMID 7790418. Meiniel A (March 2001 ... Rahner-Welsch S, Vogel J, Kuschinsky W (July 1995). "Regional congruence and divergence of glucose transporters (GLUT1) and ... Hypendymal cells and ependymal cells both are secretory in nature; their processes project to local blood vessels and also to ... All capillaries in the central nervous system with a functional blood-brain barrier express glucose transporters (GLUT1). These ...
Journal of Cerebral Blood Flow and Metabolism. 9 (6): 786-794. doi:10.1038/jcbfm.1989.112. PMID 2684992. Blin J, Ray CA, Chase ... TN, Piercey MF (1991). "Regional cerebral glucose metabolism compared in rodents and humans". Brain Research. 568 (1-2): 215- ...
"Quantitative determination of regional cerebral blood-flow in man". The Lancet. 278 (7206): 806-807. doi:10.1016/s0140-6736(61) ... 91092-3. Lassen, Niels A.; Ingvar, David H. [in Swedish] (1972). "Radioisotopic assessment of regional cerebral blood flow". ... There is a Niels Lassen Award presented by the International Society for Cerebral Blood Flow and Metabolism (ISCBFM). ((The ... Olaf B. Paulson (1997). "Niels A. Lassen, M.D., Ph.D.: 1926-1997". Journal of Cerebral Blood Flow & Metabolism. 17 (10): 1005- ...
Kendal, WS (2001). "A stochastic model for the self-similar heterogeneity of regional organ blood flow". Proc Natl Acad Sci U S ... Bassingthwaighte, JB (1989). "Fractal nature of regional myocardial blood flow heterogeneity". Circ Res. 65 (3): 578-590. doi: ... measles epidemiology HIV epidemiology, the geographic clustering of childhood leukemia blood flow heterogeneity the genomic ...
Ball, RH; Espinoza, MI; Parer, JT (1994). "Regional blood flow in asphyxiated fetuses with seizures". Am J Obstet Gynecol. 170 ...
"Regional cerebral blood flow throughout the sleep-wake cycle. An H2(15)O PET study". Brain. 120 (7): 1173-1197. doi:10.1093/ ...
Paradis, G R; Kelly, P J (1975-03-01). "Blood flow and mineral deposition in canine tibial fractures". The Journal of Bone and ... Due to regional acceleratory phenomenon, repeated biopsies of the same bone may perturb the data being gathered. Transient RAP ... Regional acceleratory phenomenon (RAP) is a sudden acceleration of normal tissue processes in reaction to noxious stimuli. It ... The effects of regional acceleratory phenomenon can be positive or negative. A study in rabbits suggested that, following ...
Gk, Frank; Wh, Kaye; P, Greer; Cc, Meltzer; Jc, Price (November 20, 2000). "Regional Cerebral Blood Flow After Recovery From ... J Cereb Blood Flow Metab 2007 27:1533-1539. PMID 17519979. Lois C, Gonzalez I, Johnson KA, Price JC. PET imaging of tau protein ... Price is also on the publication committee for the Journal of Cerebral Blood Flow and Metabolism, a leading journal in the ... Meltzer at Pittsburgh to assess whether cerebral blood flow (CBF) is reduced in aging. That revealed no decrease in CBF after ...
"Mechanically restricted regional blood flow might explain gastrointestinal pain". Nature Clinical Practice Gastroenterology & ...
During the procedure, the person is under regional or general anesthesia. A surgical tourniquet prevents blood flow to the limb ... Blood tests or imaging studies are not usually necessary. Initial treatment is typically with a cortisone shot into the ... The person is placed under regional anesthesia and a surgical tourniquet is used. The skin is opened with small curved ... People with a higher-than-average fasting blood glucose level People with previous hand injury People with Ledderhose disease ( ...
"Regional cerebral blood flow throughout the sleep-wake cycle. An H2(15)O PET study". Brain. 120 (7): 1173-1197. doi:10.1093/ ... PET studies seem to indicate that there is a correlation between blood flow in the pontine tegmentum and REM sleep Pontine ...
July 1997). "Regional cerebral blood flow throughout the sleep-wake cycle. An H2(15)O PET study". Brain. 120 ( Pt 7) (7): 1173- ... Hofle N, Paus T, Reutens D, Fiset P, Gotman J, Evans AC, Jones BE (June 1997). "Regional cerebral blood flow changes as a ... NREM sleep is characterized by decreased global and regional cerebral blood flow. It constitutes ~80% of all sleep in adult ... Mazoyer B, Houdé O, Joliot M, Mellet E, Tzourio-Mazoyer N (September 2009). "Regional cerebral blood flow increases during ...
"Quantitative determination of regional cerebral blood-flow in man". The Lancet. 278 (7206): 806-807. doi:10.1016/s0140-6736(61) ... Lassen NA, Ingvar DH [in Swedish], Skinhøj E [in Danish] (October 1978). "Brain Function and Blood Flow". Scientific American. ... Certain techniques such as fMRI image tissues (particularly cerebral tissues) by blood flow and thus show metabolism. Also, ... Some studies require the labeling of a patient's own blood cells with a radionuclide (leukocyte scintigraphy and red blood cell ...
"Quantitative determination of regional cerebral blood-flow in man". The Lancet. 278 (7206): 806-807. doi:10.1016/s0140-6736(61) ... Lassen, Niels A.; Ingvar, David H. [in Swedish]; Skinhøj, Erik [in Danish] (October 1978). "Brain Function and Blood Flow". ... as well as the flow rates of streams and rivers. In geology, archaeology, and paleontology, natural radionuclides are used to ...
"Regional cerebral blood flow through the sleep-wake cycle". Brain. Oxford University Press. 120: 1173-1197. doi:10.1093/brain/ ... Studies detect an increase of blood flow in a specific brain region and then credit that region with a role in generating ... Non-invasive measures of brain activity like electroencephalogram (EEG) voltage averaging or cerebral blood flow cannot ...
... controlling blood pressure; and modulating the regional flow of blood to tissues. In performing these roles, eicosanoids most ... blood flow to tissues, and/or blood pressure. However, their function and relevancy to human physiology and pathology have not ... The blood vessels engorge and the injury reddens. Swelling-LTB4 makes the blood vessels more permeable. Plasma leaks out into ... and other blood vessels as well as on the kidney's reabsorption of sodium and water, and act to reduce blood pressure and ...
"Reduced regional cerebral blood flow in non-psychotic violent offenders". Psychiatry Research: Neuroimaging. 98 (1): 29-41. doi ... Reduced Cerebral Blood Flow in Angular Gyrus. A couple of studies found reduced cerebral blood flow in angular gyrus of ... 2011). "Mindfulness practice leads to increases in regional brain gray matter density". Psychiatry Research: Neuroimaging. 191 ...
Fallon BA, Keilp J, Prohovnik I, Heertum RV, Mann JJ (2003). "Regional cerebral blood flow and cognitive deficits in chronic ... history of tick exposure and possibly testing for specific antibodies in the blood. Blood tests are often falsely negative in ... If the removed tick is full of blood a single dose of doxycycline may be used to prevent the development of infection but is ... Unlike blood and intrathecal antibody tests, CSF pleocytosis tests revert to normal after infection ends and therefore can be ...
Marion, DW; Darby, J; Yonas, H (1991). "Acute regional cerebral blood flow changes caused by severe head injuries". J Neurosurg ...
Methionine enkephalin as a possible neuromodulator of regional cerebral blood flow. Experientia, 41(7), 932-933. https://doi. ...
August 2000). "Continuous monitoring of regional cerebral blood flow: experimental and clinical validation of a novel thermal ... Perfusion is measured as the rate at which blood is delivered to tissue, or volume of blood per unit time (blood flow) per unit ... extra blood flow in them is used for thermoregulation of a body. In addition to delivering oxygen, blood flow helps to ... Cerebral blood flow determination by rapid-sequence computed-tomography: theoretical analysis. Radiology 137: 679-686, December ...
April 2010). "Regional cerebral blood flow changes in female to male gender identity disorder". Psychiatry and Clinical ... to compare the regional cerebral blood flow (rCBF) of 11 gynephilic trans men with that of 9 androphilic cis females. Although ... the study did reveal that the gynephilic trans men showed significant decrease in blood flow in the left anterior cingulate ... Luders E, Sánchez FJ, Gaser C, Toga AW, Narr KL, Hamilton LS, Vilain E (July 2009). "Regional gray matter variation in male-to- ...
Devous MD, Trivedi MH, Rush AJ (April 2001). "Regional cerebral blood flow response to oral amphetamine challenge in healthy ... reduced blood flow to the hands and feet), and tachycardia (increased heart rate). Sexual side effects in males may include ... Collaborators (2015). "Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of ... The most concerning short-term adverse effects of stimulants, such as elevated blood pressure and heart rate, waned in long- ...
Devous MD, Trivedi MH, Rush AJ (April 2001). "Regional cerebral blood flow response to oral amphetamine challenge in healthy ... Following absorption into the blood stream, lisdexamfetamine is completely converted by red blood cells to dextroamphetamine ... reduced blood flow to the hands and feet), and tachycardia (increased heart rate). Sexual side effects in males may include ... Collaborators (2015). "Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of ...
Smoking also has a deleterious effect on regional cerebral blood flow (rCBF). The chances of having a stroke increase with the ... "Effects of smoking on regional cerebral blood flow in neurologically normal subjects". Stroke: A Journal of Cerebral ... Transfusion therapy lowers the risk for a new silent stroke in children who have both abnormal cerebral artery blood flow ... The blood cells in sickle cell disease are abnormally shaped (sickle-shaped) and may form clots or block blood vessels. ...
"Deep dyslexia and right hemisphere reading-a regional cerebral blood flow study". Aphasiology. 11 (12): 1139-1158. doi:10.1080/ ...
Devous MD, Trivedi MH, Rush AJ (April 2001). "Regional cerebral blood flow response to oral amphetamine challenge in healthy ... Following absorption into the blood stream, lisdexamfetamine is completely converted by red blood cells to dextroamphetamine ... After oral ingestion, lisdexamfetamine is broken down by enzymes in red blood cells to form L-lysine, a naturally occurring ... The most concerning short-term adverse effects of stimulants, such as elevated blood pressure and heart rate, waned in long- ...
Devous MD, Trivedi MH, Rush AJ (April 2001). "Regional cerebral blood flow response to oral amphetamine challenge in healthy ... reduced blood flow to the hands and feet), and tachycardia (increased heart rate). Sexual side effects in males may include ... Collaborators (2015). "Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of ... The most concerning short-term adverse effects of stimulants, such as elevated blood pressure and heart rate, waned in long- ...
... JAMA. 1964 Feb 22;187:601-3. doi: 10.1001/jama. ...
During the dipyridamole infusion, the increases in phasic blood flow, the distributions of regional myocardial blood flow, and ... Relationship between regional myocardial blood flow and thallium-201 distribution in the presence of coronary artery stenosis ... Regional myocardial blood flow was measured during control conditions with radioisotope-labeled microspheres, and the phasic ... and thallium-201 activity and regional myocardial blood flow were measured. Curvilinear regression analyses between thallium- ...
Measurement of an increase in regional cerebral blood flow induced by neural activation (e.g., performing a cognitive task) ...
The patients regional cerebral blood flow imaging was obtained using N-isopropyl-p-123IMP SPECT. Regional cerebral blood flow ... Regional cerebral blood flow also was decreased in a similar manner (Fig 1D). Regional relative CBF ratios to CBF were 79% (Z ... Regional Cerebral Glucose Metabolism and Blood Flow in a Patient with Marchiafava-Bignami Disease. Kazunari Ishii, Yoshitaka ... Regional Cerebral Glucose Metabolism and Blood Flow in a Patient with Marchiafava-Bignami Disease ...
Redistribution of regional cerebral blood flow after glycerol infusion in acute cerebral infarction. ERWIN O. OTT, NlNANl T. ... Redistribution of regional cerebral blood flow after glycerol infusion in acute cerebral infarction ...
Evoked response potentials and regional cerebral blood flow in somatization disorder. Leigh James*, Andrew Singer, Yvonne ... Evoked response potentials and regional cerebral blood flow in somatization disorder. In: Psychotherapy and Psychosomatics. ... Evoked response potentials and regional cerebral blood flow in somatization disorder. / James, Leigh; Singer, Andrew; Zurynski ... Evoked response potentials and regional cerebral blood flow in somatization disorder. Psychotherapy and Psychosomatics. 1987 ...
"Regional Blood Flow" by people in this website by year, and whether "Regional Blood Flow" was a major or minor topic of these ... "Regional Blood Flow" by people in Profiles.. * Pancreatic regional blood flow links the endocrine and exocrine diseases. J Clin ... "Regional Blood Flow" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical ... Regional Blood Flow*Regional Blood Flow. *Blood Flow, Regional. *Blood Flows, Regional ...
title = "Regional Cerebral Blood Flow in Severe Developmental Dyslexia",. abstract = "Regional cerebral blood flow was measured ... Regional Cerebral Blood Flow in Severe Developmental Dyslexia. Judith M. Rumsey, Karen Faith Berman, Martha B. Denckla, Susan D ... Regional Cerebral Blood Flow in Severe Developmental Dyslexia. / Rumsey, Judith M.; Berman, Karen Faith; Denckla, Martha B. et ... Regional Cerebral Blood Flow in Severe Developmental Dyslexia. In: Archives of neurology. 1987 ; Vol. 44, No. 11. pp. 1144-1150 ...
The blood flow was measured by the intra-arterial injection of x ... Regional cerebral blood flow (rCBF) was studied in ten patients ... Regional cerebral blood flow (rCBF) was studied in ten patients with focal cortical epilepsy. The blood flow was measured by ... Regional Cerebral Blood Flow in Focal Cortical Epilepsy. Kjeld Hougaard, MD; Tadato Oikawa, MD; Edda Sveinsdottir, MD; et al ... Regional Cerebral Blood Flow in Focal Cortical Epilepsy. Arch Neurol. 1976;33(8):527-535. doi:10.1001/archneur. ...
PURPOSE To test a hypothesis of regional variation in the effect of experimental glaucoma on choroidal blood flow (ChBF) and ... Regional choroidal blood flow and multifocal electroretinography in experimental glaucoma in rhesus macaques. Invest Ophthalmol ... Regional choroidal blood flow and multifocal electroretinography in experimental glaucoma in rhesus macaques. ... The mean blood flow was 893 ± 123 and 481 ± 37 μL/min in the control and glaucomatous eyes, respectively. The ChBF showed ...
Endothelial heterogeneity associated with regional athero-susceptibility and adaptation to disturbed blood flow in vivo. Semin ... Endothelial heterogeneity associated with regional athero-susceptibility and adaptation to disturbed blood flow in vivo. ... Endothelial heterogeneity associated with regional athero-susceptibility and adaptation to disturbed blood flow in vivo. ...
Nonworking skeletal muscle blood flow decreased by 30 ± 10%. Renal blood flow was lowered by 16 ± 2%. The lower visceral organs ... Nonworking skeletal muscle blood flow decreased by 30 ± 10%. Renal blood flow was lowered by 16 ± 2%. The lower visceral organs ... Nonworking skeletal muscle blood flow decreased by 30 ± 10%. Renal blood flow was lowered by 16 ± 2%. The lower visceral organs ... Nonworking skeletal muscle blood flow decreased by 30 ± 10%. Renal blood flow was lowered by 16 ± 2%. The lower visceral organs ...
Cholinergic stimulation alters performance and task-specific regional cerebral blood flow during working memory. / Furey, M. L ... Cholinergic stimulation alters performance and task-specific regional cerebral blood flow during working memory. Proceedings of ... Cholinergic stimulation alters performance and task-specific regional cerebral blood flow during working memory. In: ... Dive into the research topics of Cholinergic stimulation alters performance and task-specific regional cerebral blood flow ...
The flow-enhancing property is lost during metabolization in the lung. Since no difference exists between the therapeutic ... efficacy of intraarterial and intravenous PGE1, the impact on muscular blood flo … ... Increase of muscular blood flow by intra-arterial PGE1 averaged 80%. A steal phenomenon was not observed. The amount of flow ... Prostaglandin E1 in peripheral vascular disease: a PET study of muscular blood flow Scand J Clin Lab Invest. 1998 Apr;58(2):109 ...
... at both regional and network levels. Here, we review these studies, focusing mainly on the new mechanistic insights provided by ... at both regional and network levels. Here, we review these studies, focusing mainly on the new mechanistic insights provided by ...
There were no significant changes in blood pressure. Consuming a high-fat meal prior to 180 min of uninterrupted sitting ... Local measures of femoral artery PWVß and blood flow provide additional mechanistic information that complements regional ... Blood flow was calculated from continuous diameter and mean blood velocity recordings using the following equation: 3.14 × ( ... As shown in Table 2, there were no significant interactions or main effects for blood flow, diameter, or shear rate at the ...
Global Blood Flow Measurement Devices Market Report 2022 comes with the extensive industry analysis by ... Global Blood Flow Measurement Devices Market Overview:,br, ... Regional Analysis:. North America (U.S., Canada, Mexico). ... 7.1.5 Blood Flow Measurement Devices Industry Concentration Ratio (CR5 and HHI). 7.1.6 Top 5 Blood Flow Measurement Devices ... 7.1.5 Blood Flow Measurement Devices Industry Concentration Ratio (CR5 and HHI). 7.1.6 Top 5 Blood Flow Measurement Devices ...
Sevoflurane and nitrous oxide increase regional cerebral blood flow (rCBF) and regional cerebral blood volume (rCBV) in a drug- ... Sevoflurane and nitrous oxide increase regional cerebral blood flow (rCBF) and regional cerebral blood volume (rCBV) in a drug- ... Relative changes versus awake in regional cerebral blood flow (rCBF), mean arterial pressure (MAP), and regional cerebral blood ... Relative changes versus awake in regional cerebral blood flow (rCBF), mean arterial pressure (MAP), and regional cerebral blood ...
Estimation of regional cerebral blood flow using N-isopropyl-p-123I iodo amphetamine acquisition data from the lungs and brain ... Estimation of regional cerebral blood flow using N-isopropyl-p-123I iodo amphetamine acquisition data from the lungs and brain ... Dive into the research topics of Estimation of regional cerebral blood flow using N-isopropyl-p-123I iodo amphetamine ... and verified its usefulness for quantification of regional cerebral blood flow (rCBF). In this study, we attempted to develop ...
Blood Flow Metab. 13 (3): 526-30. doi:10.1038/jcbfm.1993.68. PMID 8478410. "Launch of tablet to make life easier for dogs in ... Huber M, Kittner B, Hojer C, Fink GR, Neveling M, Heiss WD (1993). "Effect of propentofylline on regional cerebral glucose ...
... regional cerebral blood flow was measured ictally in 12 mature infants with recurrent seizures and compared with a reference ... To examine whether blood flow to the white matter is relatively more reduced at low blood pressure than is blood flow to the ... 110 Purpose: To evaluate the feasibility of performing measurements of cerebral blood flow (CBF) in human infants with MRI flow ... Cerebral white matter blood flow and arterial blood pressure in preterm infants ...
Regional cerebral blood flow in affective disorder. Acta Psychiatr Scand Suppl. (1993) 371:48-53. doi: 10.1111/j.1600-0447.1993 ... of the maximal cerebral blood flow appear in green, while areas at 90% of maximal cerebral blood flow appear in red. It is ... Changes in regional cerebral blood flow after electroconvulsive therapy for depression. J ECT. (2001) 17:15-21. doi: 10.1097/ ... Silfverskiöld P, Risberg J. Regional cerebral blood flow in depression and mania. Arch Gen Psychiatry. (1989) 46:253-9. doi: ...
Pancreatic regional blood flow links the endocrine and exocrine diseases. Pancreatic regional blood flow links the endocrine ... However, this is inconsistent with the current model of unidirectional blood flow, which is strictly from islets to exocrine ... instance:"regional") AND ( year_cluster:("2002") AND pais_afiliacao:("^iUnited States^eEstados"))(instance:"regional") AND ( ... which implies bidirectional blood flow between islets and exocrine cells. ...
Abnormal regional cerebral blood flow in childhood autism. Brain 2000, 123, 1838-1844. [Google Scholar] [CrossRef][Green ... Lou, H.C.; Lassen, N.A.; Friis-Hansen, B. Low Cerebral Blood Flow in Hypotensive Perinatal Distress. Acta Neurol. Scand. 1977, ... Reduction in cerebral blood flow volume in infants complicated with hypoxic ischemic encephalopathy resulting in cerebral palsy ... along with a reduction in cerebral blood flow (CBF) [6,19,20]. Although the role of hypoxia in ASD is still elusive, van ...
Regional Blood Flow. Mah E, Pei R, Guo Y, Masterjohn C, Ballard KD, Taylor BA, Taylor AW, Traber MG, Volek JS, Bruno RS. 2015. ...
relative blood flow regional blood flow RBG. random blood glucose. RBILD. respiratory bronchiolitis-associated. interstitial ...
8 Astrocytes interact with blood vessels, pericytes, and epithelial cells to organize CNS flow and modulate the blood-brain ... Regional islands of non-overlapping astrocytes consisting of thousands of synapses are formed.10 This allows synaptic and blood ... Determinants of regional and local diversity within the astroglial lineage of the normal central nervous system. Journal of ... Astrocytic modulation of blood brain barrier: perspectives on Parkinsons disease. Frontiers in Cellular Neuroscience, 8;211 ( ...
1995) Regional cerebral blood flow during object naming and word reading. Hum Brain Mapp 3:93-106. ... which is based on monitoring regional changes in blood oxygenation resulting from neural activity (Ogawa et al., 1990, 1992). ... Compared with the resting state, performance of the tone task produced blood oxygenation changes in multiple areas of both ... Preliminary studies using this language task demonstrated left hemisphere lateralization of blood oxygenation responses and a ...
Cerebral blood flow (CBF) is an indirect marker of neuronal function. In healthy adults, fasting increases CBF, reflecting ... Cerebral blood flow (CBF) is an indirect marker of neuronal function. In healthy adults, fasting increases CBF, reflecting ... Regional cerebral blood flow after recovery from anorexia and bulimia nervosa. Int J Eat Disord (2007) 40(6):488-92. doi: ... Regional cerebral blood flow in weight-restored anorexia nervosa: a preliminary study. Dev Med Child Neurol (2001) 43(4):239-42 ...
  • Regional cerebral blood flow (rCBF) was studied in ten patients with focal cortical epilepsy. (jamanetwork.com)
  • To identify associated changes in the functional brain response, we studied performance measures and regional cerebral blood flow (rCBF) using positron emission tomography (PET) in healthy subjects during performance of a WM task. (arizona.edu)
  • The authors quantified the effects of sevoflurane and propofol as sole anesthetics and in combination with N2O on regional cerebral blood flow (rCBF), metabolic rate of oxygen (rCMRO2), and blood volume (rCBV) in the living human brain using positron emission tomography. (silverchair.com)
  • Aim: Previously, we devised a method for estimating 123 I labeled N-isopropyl-p-iodo -amphetamine ( 123 I IMP) arterial blood activity at 10 minutes after intravenous injection of 123 I IMP (Ca10) without any blood sampling using 123 I IMP autoradiography (ARG) acquisition data, and verified its usefulness for quantification of regional cerebral blood flow (rCBF). (elsevierpure.com)
  • H(2)(15)O]-Positron Emission Tomography (PET) was used to examine regional cerebral blood flow (rCBF) after administration of a single oral dose of the serotonin realeaser and uptake inhibitor MDMA (1.7 mg/kg) or placebo to 16 MDMA-naïve subjects. (researchgate.net)
  • PET imaging revealed decreased regional cerebral blood flow (rCBF) in areas including the left amygdala, dorsal anterior cingulate, posterior cingulate, medial temporal lobe (MTL), and bilateral insula (Gamma et al, 2000). (researchgate.net)
  • We report a patient with MBD, in whom cerebral metabolism and blood flow were studied with [ 18 F]-2-fluoro-2-deoxy-D-glucose (FDG) PET and N -isopropyl- p -[ 123 I]iodoamphetamine (IMP) SPECT. (ajnr.org)
  • Effects of levodopa on regional cerebral metabolism and blood flow" by J. H. Ko, R. P. Lerner et al. (hofstra.edu)
  • These reductions in flow and metabolism were partly attenuated by adjunct N2O. (silverchair.com)
  • Thus, local blood flow, metabolism, and reaction, by lowering the Dose response is the most fundamental concept of toxicology. (cdc.gov)
  • Measurement of an increase in regional cerebral blood flow induced by neural activation (e.g., performing a cognitive task) using the techniques of functional magnetic resonance imaging ( fMRI ) and positron emission tomography ( PET ). (emf-portal.org)
  • We conducted a positron emission tomography (PET) study of MBF with 15O-water as flow tracer. (nih.gov)
  • Cardiac output and blood flows to most tissues were determined by radioactive microsphere distribution. (elsevierpure.com)
  • However, this is inconsistent with the current model of unidirectional blood flow , which is strictly from islets to exocrine tissues . (bvsalud.org)
  • These are in part caused by decreased blood supply to the affected tissues as the condition progresses. (eorthopod.com)
  • Global Blood Flow Measurement Devices Market Report 2022 comes with the extensive industry analysis by Introspective Market Research with development components, patterns, flows and sizes. (bharatbook.com)
  • Neurons don't store their energy, so regional brain activity is closely tied to changes in blood-oxygen - the fuel - where healthy blood flow patterns (which carry the oxygen to your cells as needed) are crucial for a high-functioning and growing brain. (geeky-gadgets.com)
  • Divergent regional patterns of cerebral hypoperfusion and gray matter atrophy in mild cognitive impairment patients. (mpg.de)
  • The key to a good outcome in patients with cardiogenic shock is an organized approach, with rapid diagnosis and prompt initiation of pharmacologic therapy to maintain blood pressure and cardiac output and respiratory support, as well as reversal of the underlying cause. (medscape.com)
  • The enlarged cardiac silhouette on this image is due to congestive heart failure due to the effects of chronic high blood pressure on the left ventricle. (medscape.com)
  • Complex Regional Pain Syndrome (CRPS) is divided into two categories, CRPS I and CRPS II. (eorthopod.com)
  • Complex regional pain syndrome more commonly affects the hand or foot, but may spread further up the affected limb and even into the opposite limb. (eorthopod.com)
  • Complex regional pain syndrome (CRPS) is a rare clinical syndrome characterized by debilitating pain , swelling, and vasomotor dysfunction of an extremity. (medicinenet.com)
  • The onset of complex regional pain syndrome (CRPS) is usually linked to a wide range of injuries resulting from trauma such as ankle sprain , bug bite , or after casting, surgery, immobilization, or a procedure such as venipuncture and intramuscular injection. (medicinenet.com)
  • What are the signs and symptoms of complex regional pain syndrome? (medicinenet.com)
  • Both complex regional pain syndrome (CRPS) I and II have a hallmark of allodynia, severe hyperalgesia, edema , skin changes, and abnormal alterations in sudomotor and vasomotor function. (medicinenet.com)
  • Complex regional pain syndrome (CRPS) is chronic neuropathic pain that follows soft-tissue or bone injury (type I) or nerve injury (type II) and lasts longer and is more severe than expected for the original tissue damage. (msdmanuals.com)
  • CRPS type I was previously known as reflex sympathetic dystrophy (see also Complex Regional Pain Syndrome: Treatment Guidelines ), and type II was known as causalgia. (msdmanuals.com)
  • Ischemic stroke (see the image below) is characterized by the sudden loss of blood circulation to an area of the brain, resulting in a corresponding loss of neurologic function. (medscape.com)
  • Relationship between regional myocardial blood flow and thallium-201 distribution in the presence of coronary artery stenosis and dipyridamole-induced vasodilation. (jci.org)
  • This study assesses the relationship between the distribution of thallium-201 and myocardial blood flow during coronary vasodilation induced by intravenous dipyridamole in canine models of partial and complete coronary artery stenosis. (jci.org)
  • 10 dogs were chronically instrumented with catheters in the left atrium and aorta and with a balloon occluder and electromagnetic flow probe on the proximal left circumflex coronary artery. (jci.org)
  • Dipyridamole was then infused intravenously until phasic coronary blood flow increased to match peak hyperemic values. (jci.org)
  • The left circumflex coronary artery was either partially occluded to reduce phasic blood flow to control values (group 1) or it was completely occluded (group 2), and thallium-201 and a second microsphere label were injected. (jci.org)
  • These data provide basic validation that supports the use of intravenous dipyridamole and thallium-201 as an alternative to exercise stress and thallium-201 for evaluating the effects of coronary occlusive lesions on the distribution of regional myocardial blood flow. (jci.org)
  • Early and definitive restoration of coronary blood flow (ie, early revascularization) is the most important intervention for achieving an improved survival rate. (medscape.com)
  • 5 min later, the animals were sacrificed, the left ventricle was sectioned into 1-2-g samples, and thallium-201 activity and regional myocardial blood flow were measured. (jci.org)
  • Magnetic resonance angiography reveals increased arterial blood supply and tumorigenesis following high fat feeding in a mouse model of triple-negative breast cancer. (uchicago.edu)
  • Here, large-scale image capture was used to examine the spatial relationship between islets and blood vessels in the following species human , monkey , pig, rabbit , ferret , and mouse . (bvsalud.org)
  • 8 Astrocytes interact with blood vessels, pericytes, and epithelial cells to organize CNS flow and modulate the blood-brain barrier (BBB). (news-medical.net)
  • They also regulate blood vessels and sweat glands. (eorthopod.com)
  • These chemicals cause vasodilation (opening of the blood vessels). (eorthopod.com)
  • Of particular importance to the present study is the prior result of decreased regional brain blood flow in the insula, a region implicated in visceral and somatosensory sensation, following MDMA administration (Gamma et al, 2000) . (researchgate.net)
  • Vascularizing the pancreas in this way may allow an entire downstream region of islets and acinar cells to be simultaneously exposed to changes in the blood levels of glucose , hormones , and other circulating factors. (bvsalud.org)
  • Changes in Local Cerebral Blood Flow, Glucose Utilizataion, and Mitochondrial Function Following Traumatic Brain Injury in Rats. (thieme-connect.de)
  • The blood flow was measured by the intra-arterial injection of xenon 133 ( 133 Xe), and the isotope clearance was recorded by a multidetector scintillation camera with 254 detectors. (jamanetwork.com)
  • There is no reliable data in man concerning the amount of increase in muscular blood flow (MBF) of the calf, and the difference between intra-arterial and intravenous application. (nih.gov)
  • Flow velocity and pulsatility index were measured in the middle cerebral, basilar and intracranial internal carotid arteries of a sample of 141 diabetic patients with no other risk factors, and 132 age- and sex-matched healthy controls. (who.int)
  • A noninvasive technique that uses the differential absorption properties of hemoglobin and myoglobin to evaluate tissue oxygenation and indirectly can measure regional hemodynamics and blood flow. (bvsalud.org)
  • During intravenous PGE1, muscular blood flow remained unchanged. (nih.gov)
  • Since no difference exists between the therapeutic efficacy of intraarterial and intravenous PGE1, the impact on muscular blood flow is not as important as suggested previously. (nih.gov)
  • No group differences in overall level or in pattern of gray matter flow were seen under relatively undemanding cognitive conditions. (johnshopkins.edu)
  • Regional cerebral blood flow was measured under three task conditions in 14 men with severe developmental dyslexia and their control subjects using a xenon 133 inhalation technique. (johnshopkins.edu)
  • CRPS commonly occurs after an injury as minor as having blood drawn, or a sprained ankle. (eorthopod.com)
  • it is regional, even when caused by injury to a specific nerve, as occurs in CRPS type II. (msdmanuals.com)
  • Pancreatic regional blood flow links the endocrine and exocrine diseases. (uchicago.edu)
  • An increasing number of studies have demonstrated that disease states of the endocrine or exocrine pancreas aggravate one another, which implies bidirectional blood flow between islets and exocrine cells . (bvsalud.org)
  • During the dipyridamole infusion, the increases in phasic blood flow, the distributions of regional myocardial blood flow, and the relationships between thallium-201 localization and regional blood flow were comparable to values previously observed in exercising dogs with similar occlusions. (jci.org)
  • Curvilinear regression analyses between thallium-201 localization and myocardial blood flow during dipyridamole infusion demonstrated a slightly better fit to a second- as compared with a first-order model, indicating a slight roll-off of thallium activity as myocardial blood flow increases. (jci.org)
  • Studies during seizures all showed marked flow increases in areas presumed to participate in the seizure activity. (jamanetwork.com)
  • All nine patients studied in the interictal phase showed, either spontaneously or during activation by intermittent light, focal flow increases in areas presumed to comprise the epileptic focus. (jamanetwork.com)
  • MDMA also produced increases in blood pressure and several side effects such as jaw clenching, lack of appetite and difficulty concentrating. (researchgate.net)
  • HEG detects regional changes in the brain's energy consumption via changes in blood-oxygen. (geeky-gadgets.com)
  • The report also calculates present and past market values to forecast potential market management through the forecast period between 2022-2028.This research study of Blood Flow Measurement Devices involved the extensive usage of both primary and secondary data sources. (bharatbook.com)
  • Cerebral blood flow in diabetes mellitus: evi- tions , 1996, 10:228-242. (who.int)
  • Despite many improvements in CPB technology and circuit design, patients still undergo an intense inflammatory response when their blood comes in contact with the nonendothelial surfaces involved in extracorporeal circulation. (medscape.com)
  • Contribution of Edema and Cerebral Blood Volume to Traumatic Brain Swelling in Head-injured Patients. (thieme-connect.de)
  • From 2008 to 2012, the authors collected ACTION-GWTG data reperfusion (restoration of blood flow to the heart) on 147,466 patients admitted for STEMI at 485 Mission: Lifeline in response to a ST-segment-¬elevation myocardial hospitals across 46 states, representing 656 systems of care. (cdc.gov)
  • Moreover, FMC-to-device times fell (blood clot solvents) can all contribute to better patient significantly for patients brought directly to PCI-capable outcomes. (cdc.gov)
  • La vitesse d'écoulement du flux sanguin et l'index de pulsatilité ont été mesurés dans les artères carotides internes intercrâniennes, les artères basilaires et cérébrales moyennes d'un échantillon de 141 patients diabétiques sans autre facteur de risque et de 132 témoins en bonne santé appariés pour l'âge et le sexe. (who.int)
  • Les patients ont été répartis en deux groupes : 73 patients souffrant d'un diabète compliqué dans le premier groupe et 68 patients atteints d'un diabète non compliqué dans le deuxième groupe. (who.int)
  • Endothelial heterogeneity associated with regional athero-susceptibility and adaptation to disturbed blood flow in vivo. (uchicago.edu)
  • 4 Regional populations of astrocytes also seem to demonstrate local heterogeneity. (news-medical.net)
  • S+N especially reduced the oxygen extraction fraction, suggesting disturbed flow-activity coupling in humans at a moderate depth of anesthesia. (silverchair.com)
  • The HEGduino biofeedback kit Has been specifically designed to provide an affordable system that uses red/infrared light sensing to determine the changes in the blood-oxygen levels in your brain in real time. (geeky-gadgets.com)
  • Being able to track blood-oxygen changes in your brain provides direct insight into your brain activity and HEGduino makes creating projects using hemoencephalography (HEG) biofeedback a little easier to develop. (geeky-gadgets.com)
  • Brain Exercise: Do "brain pushups" to improve brain blood-oxygen levels as an educational, clinical, or hobbyist tool. (geeky-gadgets.com)
  • Research: Measure neocortical functioning as correlated via blood-oxygen ratio changes. (geeky-gadgets.com)
  • HEGduino enables you to see in real time how your brain blood-oxygen levels respond to your thoughts and actions, resulting in a simple and elegant biofeedback system. (geeky-gadgets.com)
  • Global hypoxia-ischemia interrupts oxygen delivery and blood flow to the entire brain. (cdc.gov)
  • Blood flow to torso and limb skin fell by 38 ± 4 and 38 ± 6%, respectively, and similar reductions occurred in adipose tissue blood flow. (elsevierpure.com)
  • There were no significant changes in blood pressure. (nature.com)
  • The HEG is a way to alter brain function through a series of "training" sessions based on the changes in blood flow to different areas of the brain. (geeky-gadgets.com)
  • However, SUVr may potentially be affected by changes in blood flow, whereas quantitative measures such as nondisplaceable binding potential (BPND) are not. (lu.se)
  • For 18F-flortaucipir PET, the sensitivity of SUVr for changes in blood flow is currently unknown. (lu.se)
  • Therefore, we compared semiquantitative (SUVr) and quantitative (BPND) parameters of longitudinal 18F-flortaucipir PET scans and assessed their vulnerability to changes in blood flow. (lu.se)
  • Thermoregulatory function, that is, heat dissipative responses such as skin blood flow (SkBF) and sweating to an increased body temperature, is critical during physical work or exercise in warm and hot conditions and during hyperthermia. (intechopen.com)
  • PURPOSE To test a hypothesis of regional variation in the effect of experimental glaucoma on choroidal blood flow (ChBF) and retinal function. (wisc.edu)
  • A Brain blood flow biofeedback machine meets affordable IoT technology designed and manufactured by AlasKit. (geeky-gadgets.com)
  • It takes less than ten minutes of using the device to learn how to change your brain blood flow directly. (geeky-gadgets.com)
  • This allows fluid to leak from the blood vessel into the surrounding tissue. (eorthopod.com)
  • Cerebral Blood Flow and Secondary Growth of Brain Tissue Necrosis after Trauma. (thieme-connect.de)
  • Neurovascular dysfunction, including blood-brain barrier (BBB) breakdown and cerebral blood flow (CBF) dysregulation and reduction, is increasingly recognized as contributing to Alzheimer disease. (medscape.com)
  • This study employs computer-aided imaging technologies to examine brain function in thousandths of a second (event-related brain potentials) and over a number of minutes (regional cerebral blood flow). (edu.au)
  • Evaluation of flow of chorioretinal capillaries in healthy black and white subjects using optical coherence tomography angiography. (uchicago.edu)
  • Thus during short dynamic exercise baboons redistributed blood flow away from skin, fat, nonworking muscles, and visceral organs to supply the needs of exercising muscles. (elsevierpure.com)
  • In humans, inorganic nitrate decreases blood pressure via NO generation. (sciencewatch.com)
  • Given that it is currently unknown to what order of magnitude pharmacotherapeutic interventions may induce changes in cerebral blood flow, caution may be warranted when changes in flow are potentially large(r), as in clinical trials. (lu.se)
  • An arterial line may be placed to provide continuous blood pressure monitoring. (medscape.com)
  • Anteroposterior x-ray from a 28-year old woman who presented with congestive heart failure secondary to her chronic hypertension, or high blood pressure. (medscape.com)
  • Hypertension is defined as a systolic blood pressure (SBP) of 140 mm Hg or more, or a diastolic blood pressure (DBP) of 90 mm Hg or more, or taking antihypertensive medication. (medscape.com)
  • The evaluation of hypertension involves accurately measuring the patient's blood pressure, performing a focused medical history and physical examination, and obtaining results of routine laboratory studies. (medscape.com)
  • Regional SUVrs were compared with corresponding distribution volume ratio (BPND + 1) using paired t tests. (lu.se)
  • Increase of blood flow in the ischaemic leg is believed to represent the main action of prostaglandin E1 (PGE1) in the therapy of peripheral vascular disease (PVD). (nih.gov)
  • Competitive analysis is the study of strength and weakness, market investment, market share, market sales volume, market trends of major players in the market.The Blood Flow Measurement Devices market study focused on including all the primary level, secondary level and tertiary level competitors in the report. (bharatbook.com)
  • 13 Bouma G J, Muizelaar J P, Fatouros P. Pathogenesis of Traumatic Brain Swelling: Role of Cerebral Blood Volume. (thieme-connect.de)
  • Regional myocardial blood flow was measured during control conditions with radioisotope-labeled microspheres, and the phasic reactive hyperemic response to a 20-s transient occlusion was then recorded. (jci.org)
  • The global impacts of the coronavirus disease 2019 (COVID-19) are already starting to be felt, and will significantly affect the Blood Flow Measurement Devices market in 2020. (bharatbook.com)
  • Additionally, simulations were performed to model effects of larger flow changes in different binding categories. (lu.se)
  • Respiratory which inhalation dosimetric relationships contribute to this tract uptake of halothane, acetone, ethanol and diacetyl was species difference in regional airway injury is not known, but measured in male F344 rat to obtain data for model validation. (cdc.gov)