Tests to determine whether or not an individual is pregnant.
Methods of detecting pregnancy by examining the levels of human chorionic gonadotropin (HCG) in plasma or urine.
The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
A potentially life-threatening condition in which EMBRYO IMPLANTATION occurs outside the cavity of the UTERUS. Most ectopic pregnancies (>96%) occur in the FALLOPIAN TUBES, known as TUBAL PREGNANCY. They can be in other locations, such as UTERINE CERVIX; OVARY; and abdominal cavity (PREGNANCY, ABDOMINAL).
Results of conception and ensuing pregnancy, including LIVE BIRTH; STILLBIRTH; SPONTANEOUS ABORTION; INDUCED ABORTION. The outcome may follow natural or artificial insemination or any of the various ASSISTED REPRODUCTIVE TECHNIQUES, such as EMBRYO TRANSFER or FERTILIZATION IN VITRO.
A gonadotropic glycoprotein hormone produced primarily by the PLACENTA. Similar to the pituitary LUTEINIZING HORMONE in structure and function, chorionic gonadotropin is involved in maintaining the CORPUS LUTEUM during pregnancy. CG consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is virtually identical to the alpha subunits of the three pituitary glycoprotein hormones (TSH, LH, and FSH), but the beta subunit is unique and confers its biological specificity (CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN).
The beta subunit of human CHORIONIC GONADOTROPIN. Its structure is similar to the beta subunit of LUTEINIZING HORMONE, except for the additional 30 amino acids at the carboxy end with the associated carbohydrate residues. HCG-beta is used as a diagnostic marker for early detection of pregnancy, spontaneous abortion (ABORTION, SPONTANEOUS); ECTOPIC PREGNANCY; HYDATIDIFORM MOLE; CHORIOCARCINOMA; or DOWN SYNDROME.
The ratio of the number of conceptions (CONCEPTION) including LIVE BIRTH; STILLBIRTH; and fetal losses, to the mean number of females of reproductive age in a population during a set time period.
An assisted reproductive technique that includes the direct handling and manipulation of oocytes and sperm to achieve fertilization in vitro.
Conditions or pathological processes associated with pregnancy. They can occur during or after pregnancy, and range from minor discomforts to serious diseases that require medical interventions. They include diseases in pregnant females, and pregnancies in females with diseases.
The transfer of mammalian embryos from an in vivo or in vitro environment to a suitable host to improve pregnancy or gestational outcome in human or animal. In human fertility treatment programs, preimplantation embryos ranging from the 4-cell stage to the blastocyst stage are transferred to the uterine cavity between 3-5 days after FERTILIZATION IN VITRO.
Positive test results in subjects who do not possess the attribute for which the test is conducted. The labeling of healthy persons as diseased when screening in the detection of disease. (Last, A Dictionary of Epidemiology, 2d ed)
The process of bearing developing young (EMBRYOS or FETUSES) in utero in non-human mammals, beginning from FERTILIZATION to BIRTH.
An assisted fertilization technique consisting of the microinjection of a single viable sperm into an extracted ovum. It is used principally to overcome low sperm count, low sperm motility, inability of sperm to penetrate the egg, or other conditions related to male infertility (INFERTILITY, MALE).
Commercially prepared reagent sets, with accessory devices, containing all of the major components and literature necessary to perform one or more designated diagnostic tests or procedures. They may be for laboratory or personal use.
The beginning third of a human PREGNANCY, from the first day of the last normal menstrual period (MENSTRUATION) through the completion of 14 weeks (98 days) of gestation.
The last third of a human PREGNANCY, from the beginning of the 29th through the 42nd completed week (197 to 294 days) of gestation.
Congenital malformations of the central nervous system and adjacent structures related to defective neural tube closure during the first trimester of pregnancy generally occurring between days 18-29 of gestation. Ectodermal and mesodermal malformations (mainly involving the skull and vertebrae) may occur as a result of defects of neural tube closure. (From Joynt, Clinical Neurology, 1992, Ch55, pp31-41)
A tube of ectodermal tissue in an embryo that will give rise to the CENTRAL NERVOUS SYSTEM, including the SPINAL CORD and the BRAIN. Lumen within the neural tube is called neural canal which gives rise to the central canal of the spinal cord and the ventricles of the brain. For malformation of the neural tube, see NEURAL TUBE DEFECTS.
A malformation of the nervous system caused by failure of the anterior neuropore to close. Infants are born with intact spinal cords, cerebellums, and brainstems, but lack formation of neural structures above this level. The skull is only partially formed but the eyes are usually normal. This condition may be associated with folate deficiency. Affected infants are only capable of primitive (brain stem) reflexes and usually do not survive for more than two weeks. (From Menkes, Textbook of Child Neurology, 5th ed, p247)
Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)
The visualization of tissues during pregnancy through recording of the echoes of ultrasonic waves directed into the body. The procedure may be applied with reference to the mother or the fetus and with reference to organs or the detection of maternal or fetal disease.
Cells lining the outside of the BLASTOCYST. After binding to the ENDOMETRIUM, trophoblasts develop into two distinct layers, an inner layer of mononuclear cytotrophoblasts and an outer layer of continuous multinuclear cytoplasm, the syncytiotrophoblasts, which form the early fetal-maternal interface (PLACENTA).

Pregnancy detection and the effects of age, body weight, and previous reproductive performance on pregnancy status and weaning rates of farmed fallow deer (Dama dama). (1/142)

Fallow does (n = 502) of different ages (mature, 2-yr-old, and yearling) were maintained with bucks for a 60-d breeding season to determine whether previous reproductive performance and changes in BW affect doe pregnancy rates and to compare the effectiveness of ultrasonography and serum pregnancy-specific protein B (PSPB) for the detection of pregnancy in fallow does. Ultrasonography was performed, blood samples collected, and BW recorded at buck removal (d 0) and at 30 and 90 d after buck removal. Lactational status (lactating = WET; nonlactating = DRY) were determined from farm records taken at weaning prior to each breeding season (autumn 1990 through autumn 1994). Ultrasonography and PSPB for determining pregnancy were in agreement 93% of the time. Overall pregnancy rates did not differ (P>.10) relative to age of the doe; the combined pregnancy rate was 92%. We also determined that 82.9% of does conceived early in the breeding season and that the incidence of embryonal-fetal mortality during the first 90 d after buck removal was 2.8%. In general, mature and 2-yr-old DRY does were heavier and had lower pregnancy rates than WET does. The overall weaning rate for all does was 77.9%. Loss in the number of fawns from pregnancy detection to weaning was equivalent to 14.8% for mature does, 24.7% for 2 yr old does, and 42.5% for yearling does. These data indicate that even though pregnancy rates were relatively high, further study is needed to determine the causes associated with subsequent fawn losses, particularly among yearling does. As a production tool, lactational WET/ DRY status testing was found to be an acceptable means for determining the reproductive potential of individual does within the herd. In addition, serum PSPB may be used in place of ultrasonography for pregnancy diagnosis in fallow deer as early as d 30 after buck removal.  (+info)

Pregnancy testing before high-dose radioiodine treatment: a case report. (2/142)

This case emphasizes that negative urine pregnancy testing and a written declaration of the patient are not sufficient to safely exclude an early pregnancy. Serum pregnancy testing inherently has a diagnostic gap of about 1 wk following conception. We recommend sufficient contraception at least 1 mo before radioiodine treatment in women of childbearing age.  (+info)

Does ICSI affect early serum beta-HCG in pregnancies achieved after IVF? (3/142)

This study was conducted to compare early serum human chorionic gonadotrophin (HCG) concentrations in singleton pregnancies achieved after intracytoplasmic sperm injection (ICSI), with those achieved after conventional in-vitro fertilization (IVF). Early serum HCG, 14-16 days after embryo transfer, was analysed in 99 IVF pregnancies achieved after ICSI (group A), and compared to 105 conventional IVF pregnancies (group B). All women were treated at the IVF Unit, Lis Maternity Hospital. Records were studied retrospectively. The mean +/- SE serum HCG concentration on day 14 after embryo transfer in group A was 190.5 +/- 17.4 mIU/ml, compared to 195.7 +/- 14.03 mIU/ml in group B. HCG concentration 14 days after embryo transfer in both groups A and B was higher in women with mechanical factor than in couples with male factor infertility or unexplained infertility (246 +/- 31.4, 183.3 +/- 16.4, 177.98 +/- 14.3 mIU/ml respectively). On the 16th day after embryo transfer, the HCG concentration increased, and the difference between the groups was maintained. Only in the subgroup of unexplained infertility did we find a difference in concentrations of HCG between ICSI and conventional IVF: on the 16th day following embryo transfer in this group there was a significant difference in HCG concentrations (395. 8 +/- 21 and 545.6 +/- 45.7 respectively; P = 0.04). HCG concentrations did not differ overall in the conventional IVF pregnancies compared with those achieved by ICSI. However, a statistical difference in early serum HCG concentrations was found in relation to the aetiology of infertility.  (+info)

Prevalence of home pregnancy testing among adolescents. (4/142)

OBJECTIVES: This study estimated the prevalence of home pregnancy testing among adolescents. METHODS: A survey was administered in 11 urban clinics to 600 females aged 13 to 19 years. RESULTS: The prevalence of home pregnancy test use was 34% among 474 sexually experienced youths; 77% of the users had received at least 1 negative pregnancy test result, and 48% took no further action for confirmation. Compared with those who had never used such tests, users were older, younger at sexual debut, less likely to consistently use effective birth control, and more likely to have ever been pregnant. CONCLUSIONS: Health care clinics are important sources for pregnancy prevention, but clinics may have limited opportunity to intervene with some youths who use home pregnancy tests.  (+info)

Factors affecting contraceptive use in women seeking pregnancy tests: Missouri, 1997. (5/142)

CONTEXT: If the national health objective of reducing unintended pregnancy is to be met, a better understanding is needed of barriers to women's acquisition and use of contraceptives. METHODS: A sample of 311 Missouri women who were seeking pregnancy tests in public health department clinics in 1997 and who said their potential pregnancy was unintended were asked about potential barriers to family planning. Factors affecting contraceptive use among these women were examined by frequency of use, insurance status, education and race. RESULTS: In general, the women mostly disagreed that particular factors were potential barriers to contraceptive use. For only one item--worry over the potential side effects of the hormonal injectable contraceptive--did a majority agree or strongly agree that it was a barrier to method use in the previous six months. Women who used a contraceptive infrequently were more likely than frequent users to identify 33 factors in nine areas as being potential barriers to contraceptive use. These ranged from factors involving access to services and condom-specific issues to cost-related concerns, social norms, pregnancy denial, embarrassment over discussing or obtaining birth control, worry about side effects and experience with forced sex, among others. Perceived barriers differed somewhat by insurance status in the areas of access, embarrassment, side effects and forced sex. For example, women with no insurance coverage reported a higher level of agreement that transportation problems had hindered their access to a clinic than did women with private insurance. Level of education affected agreement only in the area of side effects, with more-educated women expressing greater concern about side effects than less-educated women. The respondent's race affected agreement in six areas: access, social norms, pregnancy denial, embarrassment, forced sex and other miscellaneous concerns, such as condom use and relationship issues. CONCLUSION: Better education and improved access to and delivery of services might address several factors affecting contraceptive use that are associated with unintended pregnancy. Some barriers, however, such as those related to self-efficacy, self-esteem and fatalistic attitudes about pregnancy, would be much harder for family planning providers to resolve.  (+info)

Teenagers educating teenagers about reproductive health and their rights to confidential care.(6/142)

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Advances in ultrasound assessment in the establishment and development of pregnancy. (7/142)

Current data demonstrate that angiogenesis in the ovaries and uterus is an essential component of both follicular and luteal phases of menstrual cycle, tightly correlating with the levels of bioactive substances such as hormones, growth factors and interleukins. Ultrasound is used principally to demonstrate follicular growth, a receptive triple layer endometrium and to exclude pathologies such as fibroids and ovarian tumours. However, the development of new technologies such as CDI, CPA, 3D-US, 3D-CPA is now set to expand the role of ultrasound in the assessment of the processes in the ovaries, uterus and early pregnancy. There is growing evidence that studies of peri-follicular vascularity will predict the development of a healthy oocyte and subsequently an embryo. Endometrial blood flow studies with conventional CDI and the newer techniques of CPA and 3D-CPA will be important in predicting endometrial receptivity. Ovarian stromal vascularity appears to correlate with vascular endothelial growth factor (VEGF) levels and high vascularity is associated with PCO and a risk of ovarian hyperstimulation syndrome. 3D-CPA may improve our ability to assess ovarian and endometrial vascularization and blood circulation, to diagnose tubal patency. Increasingly, 3D ultrasound is being applied to diagnose the pathology of early singleton and multiple pregnancies.  (+info)

Comparison of various reproductive status in Sika deer (Cervus nippon) using fecal steroid analysis. (8/142)

The feasibility of fecal steroid analysis for pregnancy diagnosis and sex determination were tested in sika deer (Cervus nippon). Feces were collected from captive sika deer in June (non-breeding season and late-pregnancy period) and October (breeding season), and also from the rectum of 24 female sika deer (19 pregnant and 5 non-pregnant females) shot as part of programs for population control in February and March (mid-pregnancy period). In mid- and late-pregnancy periods, fecal progesterone concentrations were significantly higher in pregnant female than in male and non-pregnant female deer. In October, fecal testosterone concentrations were higher in adult male deer, and no difference was found between young males and females. These results suggest that fecal steroid analysis would be a useful means for estimating pregnancy status and for detecting adult male among wild deer.  (+info)

A pregnancy test is a medical diagnostic tool used to determine whether or not a woman is pregnant. These tests detect the presence of human chorionic gonadotropin (hCG), a hormone produced by the placenta after fertilization. Pregnancy tests can be performed using a variety of methods, including urine tests and blood tests.

Urine pregnancy tests are typically performed at home and involve either dipping a test strip into a sample of urine or holding the strip under a stream of urine for several seconds. The test strip contains antibodies that react with hCG, producing a visual signal such as a line or plus sign if hCG is present.

Blood pregnancy tests are performed by a healthcare provider and can detect lower levels of hCG than urine tests. There are two types of blood pregnancy tests: qualitative and quantitative. Qualitative tests simply detect the presence or absence of hCG, while quantitative tests measure the exact amount of hCG present in the blood.

Pregnancy tests are generally very accurate when used correctly, but false positives and false negatives can occur. False positives may occur due to certain medical conditions or medications that contain hCG. False negatives may occur if the test is taken too early or if it is not performed correctly. It is important to follow the instructions carefully and consult with a healthcare provider if there is any uncertainty about the results.

Immunologic pregnancy tests are a type of diagnostic test used to determine the presence of human chorionic gonadotropin (hCG) in a patient's urine or blood. hCG is a hormone produced by the placenta during pregnancy, and its levels increase rapidly in early pregnancy. Immunologic pregnancy tests use antibodies to detect the presence of hCG and produce a positive or negative result based on the amount of hCG detected. These tests are widely used as an initial screening tool for pregnancy and can provide accurate results within a few days of missed menstrual period.

Pregnancy is a physiological state or condition where a fertilized egg (zygote) successfully implants and grows in the uterus of a woman, leading to the development of an embryo and finally a fetus. This process typically spans approximately 40 weeks, divided into three trimesters, and culminates in childbirth. Throughout this period, numerous hormonal and physical changes occur to support the growing offspring, including uterine enlargement, breast development, and various maternal adaptations to ensure the fetus's optimal growth and well-being.

Ectopic pregnancy is a type of abnormal pregnancy that occurs outside the uterine cavity. The most common site for an ectopic pregnancy is the fallopian tube, accounting for about 95% of cases. This condition is also known as tubal pregnancy. Other less common sites include the ovary, cervix, and abdominal cavity.

In a normal pregnancy, the fertilized egg travels down the fallopian tube and implants itself in the lining of the uterus. However, in an ectopic pregnancy, the fertilized egg implants and starts to develop somewhere other than the uterus. The growing embryo cannot survive outside the uterus, and if left untreated, an ectopic pregnancy can cause life-threatening bleeding due to the rupture of the fallopian tube or other organs.

Symptoms of ectopic pregnancy may include abdominal pain, vaginal bleeding, shoulder pain, lightheadedness, fainting, and in severe cases, shock. Diagnosis is usually made through a combination of medical history, physical examination, ultrasound, and blood tests to measure the levels of human chorionic gonadotropin (hCG), a hormone produced during pregnancy.

Treatment for ectopic pregnancy depends on several factors, including the location, size, and growth rate of the ectopic mass, as well as the patient's overall health and desire for future pregnancies. Treatment options may include medication to stop the growth of the embryo or surgery to remove the ectopic tissue. In some cases, both methods may be used together. Early diagnosis and treatment can help prevent serious complications and improve the chances of preserving fertility in future pregnancies.

Pregnancy outcome refers to the final result or status of a pregnancy, including both the health of the mother and the newborn baby. It can be categorized into various types such as:

1. Live birth: The delivery of one or more babies who show signs of life after separation from their mother.
2. Stillbirth: The delivery of a baby who has died in the womb after 20 weeks of pregnancy.
3. Miscarriage: The spontaneous loss of a pregnancy before the 20th week.
4. Abortion: The intentional termination of a pregnancy before the fetus can survive outside the uterus.
5. Ectopic pregnancy: A pregnancy that develops outside the uterus, usually in the fallopian tube, which is not viable and requires medical attention.
6. Preterm birth: The delivery of a baby before 37 weeks of gestation, which can lead to various health issues for the newborn.
7. Full-term birth: The delivery of a baby between 37 and 42 weeks of gestation.
8. Post-term pregnancy: The delivery of a baby after 42 weeks of gestation, which may increase the risk of complications for both mother and baby.

The pregnancy outcome is influenced by various factors such as maternal age, health status, lifestyle habits, genetic factors, and access to quality prenatal care.

Chorionic Gonadotropin (hCG) is a hormone that is produced during pregnancy. It is produced by the placenta after implantation of the fertilized egg in the uterus. The main function of hCG is to prevent the disintegration of the corpus luteum, which is a temporary endocrine structure that forms in the ovary after ovulation and produces progesterone during early pregnancy. Progesterone is essential for maintaining the lining of the uterus and supporting the pregnancy.

hCG can be detected in the blood or urine as early as 10 days after conception, and its levels continue to rise throughout the first trimester of pregnancy. In addition to its role in maintaining pregnancy, hCG is also used as a clinical marker for pregnancy and to monitor certain medical conditions such as gestational trophoblastic diseases.

Chorionic Gonadotropin, beta Subunit, Human (β-hCG) is a protein that is produced by the placenta during pregnancy. It is a component of human chorionic gonadotropin (hCG), which is a hormone that is composed of two subunits: alpha and beta. The β-hCG subunit is specific to hCG and is not found in other hormones, making it a useful marker for pregnancy and certain medical conditions.

During early pregnancy, the levels of β-hCG increase rapidly and can be detected in the blood and urine. This has led to the development of pregnancy tests that detect the presence of β-hCG to confirm pregnancy. In addition to its role in pregnancy, β-hCG is also used as a tumor marker for certain types of cancer, such as germ cell tumors and choriocarcinoma.

Elevated levels of β-hCG may indicate the presence of a molar pregnancy, a condition in which a fertilized egg implants in the uterus but does not develop properly. In some cases, a molar pregnancy can become cancerous and require treatment. Therefore, monitoring β-hCG levels during pregnancy is important for detecting any potential complications.

The pregnancy rate is a measure used in reproductive medicine to determine the frequency or efficiency of conception following certain treatments, interventions, or under specific conditions. It is typically defined as the number of pregnancies per 100 women exposed to the condition being studied over a specified period of time. A pregnancy is confirmed when a woman has a positive result on a pregnancy test or through the detection of a gestational sac on an ultrasound exam.

In clinical trials and research, the pregnancy rate helps healthcare professionals evaluate the effectiveness of various fertility treatments such as in vitro fertilization (IVF), intrauterine insemination (IUI), or ovulation induction medications. The pregnancy rate can also be used to assess the impact of lifestyle factors, environmental exposures, or medical conditions on fertility and conception.

It is important to note that pregnancy rates may vary depending on several factors, including age, the cause of infertility, the type and quality of treatment provided, and individual patient characteristics. Therefore, comparing pregnancy rates between different studies should be done cautiously, considering these potential confounding variables.

Fertilization in vitro, also known as in-vitro fertilization (IVF), is a medical procedure where an egg (oocyte) and sperm are combined in a laboratory dish to facilitate fertilization. The fertilized egg (embryo) is then transferred to a uterus with the hope of establishing a successful pregnancy. This procedure is often used when other assisted reproductive technologies have been unsuccessful or are not applicable, such as in cases of blocked fallopian tubes, severe male factor infertility, and unexplained infertility. The process involves ovarian stimulation, egg retrieval, fertilization, embryo culture, and embryo transfer. In some cases, additional techniques such as intracytoplasmic sperm injection (ICSI) or preimplantation genetic testing (PGT) may be used to increase the chances of success.

Pregnancy complications refer to any health problems that arise during pregnancy which can put both the mother and the baby at risk. These complications may occur at any point during the pregnancy, from conception until childbirth. Some common pregnancy complications include:

1. Gestational diabetes: a type of diabetes that develops during pregnancy in women who did not have diabetes before becoming pregnant.
2. Preeclampsia: a pregnancy complication characterized by high blood pressure and damage to organs such as the liver or kidneys.
3. Placenta previa: a condition where the placenta covers the cervix, which can cause bleeding and may require delivery via cesarean section.
4. Preterm labor: when labor begins before 37 weeks of gestation, which can lead to premature birth and other complications.
5. Intrauterine growth restriction (IUGR): a condition where the fetus does not grow at a normal rate inside the womb.
6. Multiple pregnancies: carrying more than one baby, such as twins or triplets, which can increase the risk of premature labor and other complications.
7. Rh incompatibility: a condition where the mother's blood type is different from the baby's, which can cause anemia and jaundice in the newborn.
8. Pregnancy loss: including miscarriage, stillbirth, or ectopic pregnancy, which can be emotionally devastating for the parents.

It is important to monitor pregnancy closely and seek medical attention promptly if any concerning symptoms arise. With proper care and management, many pregnancy complications can be treated effectively, reducing the risk of harm to both the mother and the baby.

Embryo transfer is a medical procedure that involves the transfer of an embryo, which is typically created through in vitro fertilization (IVF), into the uterus of a woman with the aim of establishing a pregnancy. The embryo may be created using the intended parent's own sperm and eggs or those from donors. After fertilization and early cell division, the resulting embryo is transferred into the uterus of the recipient mother through a thin catheter that is inserted through the cervix. This procedure is typically performed under ultrasound guidance to ensure proper placement of the embryo. Embryo transfer is a key step in assisted reproductive technology (ART) and is often used as a treatment for infertility.

A "false positive reaction" in medical testing refers to a situation where a diagnostic test incorrectly indicates the presence of a specific condition or disease in an individual who does not actually have it. This occurs when the test results give a positive outcome, while the true health status of the person is negative or free from the condition being tested for.

False positive reactions can be caused by various factors including:

1. Presence of unrelated substances that interfere with the test result (e.g., cross-reactivity between similar molecules).
2. Low specificity of the test, which means it may detect other conditions or irrelevant factors as positive.
3. Contamination during sample collection, storage, or analysis.
4. Human errors in performing or interpreting the test results.

False positive reactions can have significant consequences, such as unnecessary treatments, anxiety, and increased healthcare costs. Therefore, it is essential to confirm any positive test result with additional tests or clinical evaluations before making a definitive diagnosis.

"Animal pregnancy" is not a term that is typically used in medical definitions. However, in biological terms, animal pregnancy refers to the condition where a fertilized egg (or eggs) implants and develops inside the reproductive tract of a female animal, leading to the birth of offspring (live young).

The specific details of animal pregnancy can vary widely between different species, with some animals exhibiting phenomena such as placental development, gestation periods, and hormonal changes that are similar to human pregnancy, while others may have very different reproductive strategies.

It's worth noting that the study of animal pregnancy and reproduction is an important area of biological research, as it can provide insights into fundamental mechanisms of embryonic development, genetics, and evolution.

Intracytoplasmic Sperm Injection (ICSI) is a specialized form of assisted reproductive technology (ART), specifically used in the context of in vitro fertilization (IVF). It involves the direct injection of a single sperm into the cytoplasm of a mature egg (oocyte) to facilitate fertilization. This technique is often used when there are issues with male infertility, such as low sperm count or poor sperm motility, to increase the chances of successful fertilization. The resulting embryos can then be transferred to the uterus in hopes of achieving a pregnancy.

Reagent kits, diagnostic are prepackaged sets of chemical reagents and other components designed for performing specific diagnostic tests or assays. These kits are often used in clinical laboratories to detect and measure the presence or absence of various biomarkers, such as proteins, antibodies, antigens, nucleic acids, or small molecules, in biological samples like blood, urine, or tissues.

Diagnostic reagent kits typically contain detailed instructions for their use, along with the necessary reagents, controls, and sometimes specialized equipment or supplies. They are designed to simplify the testing process, reduce human error, and increase standardization, ensuring accurate and reliable results. Examples of diagnostic reagent kits include those used for pregnancy tests, infectious disease screening, drug testing, genetic testing, and cancer biomarker detection.

The first trimester of pregnancy is defined as the period of gestational development that extends from conception (fertilization of the egg by sperm) to the end of the 13th week. This critical phase marks significant transformations in both the mother's body and the growing embryo/fetus.

During the first trimester, the fertilized egg implants into the uterine lining (implantation), initiating a series of complex interactions leading to the formation of the placenta - an organ essential for providing nutrients and oxygen to the developing fetus while removing waste products. Simultaneously, the embryo undergoes rapid cell division and differentiation, giving rise to various organs and systems. By the end of the first trimester, most major structures are present, although they continue to mature and grow throughout pregnancy.

The mother may experience several physiological changes during this time, including:
- Morning sickness (nausea and vomiting)
- Fatigue
- Breast tenderness
- Frequent urination
- Food aversions or cravings
- Mood swings

Additionally, hormonal shifts can cause various symptoms and prepare the body for potential changes in lactation, posture, and pelvic alignment as pregnancy progresses. Regular prenatal care is crucial during this period to monitor both maternal and fetal wellbeing, identify any potential complications early on, and provide appropriate guidance and support throughout the pregnancy.

The third trimester of pregnancy is the final stage of pregnancy that lasts from week 29 until birth, which typically occurs around the 40th week. During this period, the fetus continues to grow and mature, gaining weight rapidly. The mother's body also prepares for childbirth by dilating the cervix and producing milk in preparation for breastfeeding. Regular prenatal care is crucial during this time to monitor the health of both the mother and the developing fetus, as well as to prepare for delivery.

Neural Tube Defects (NTDs) are a group of birth defects that affect the brain, spine, or spinal cord. They occur when the neural tube, which forms the early brain and spinal cord of the embryo, does not close properly during fetal development. This can result in various conditions such as:

1. Anencephaly: a severe defect where most of the brain and skull are missing. Infants with anencephaly are usually stillborn or die shortly after birth.
2. Spina bifida: a condition where the spine does not close properly, leaving a portion of the spinal cord and nerves exposed. This can result in various neurological problems, including paralysis, bladder and bowel dysfunction, and hydrocephalus (fluid buildup in the brain).
3. Encephalocele: a condition where the skull does not close properly, allowing the brain to protrude through an opening in the skull. This can result in various neurological problems, including developmental delays, vision and hearing impairments, and seizures.

NTDs are thought to be caused by a combination of genetic and environmental factors, such as folic acid deficiency, obesity, diabetes, and exposure to certain medications during pregnancy. Folic acid supplementation before and during early pregnancy has been shown to reduce the risk of NTDs.

The Neural Tube is a structure that forms during the development of an embryo and eventually becomes the brain, spinal cord, and other parts of the nervous system. It is a narrow channel that runs along the back of the embryo, forming from the ectoderm (one of the three germ layers) and closing around the 23rd or 26th day after conception. Defects in the closure of the neural tube can lead to conditions such as spina bifida and anencephaly.

Anencephaly is a serious birth defect that affects the neural tube, which is the structure that develops into the brain and spinal cord. In anencephaly, the neural tube fails to close properly during fetal development, resulting in the absence of a major portion of the brain, skull, and scalp.

Anencephaly is typically diagnosed through prenatal ultrasound or other imaging tests. Unfortunately, it is a fatal condition, and most babies with anencephaly do not survive birth or live for more than a few hours or days after birth.

The exact cause of anencephaly is not fully understood, but it is believed to be related to genetic factors as well as environmental influences such as folic acid deficiency and exposure to certain medications or chemicals during pregnancy. Pregnant women are often advised to take folic acid supplements to reduce the risk of neural tube defects, including anencephaly.

An encyclopedia is a comprehensive reference work containing articles on various topics, usually arranged in alphabetical order. In the context of medicine, a medical encyclopedia is a collection of articles that provide information about a wide range of medical topics, including diseases and conditions, treatments, tests, procedures, and anatomy and physiology. Medical encyclopedias may be published in print or electronic formats and are often used as a starting point for researching medical topics. They can provide reliable and accurate information on medical subjects, making them useful resources for healthcare professionals, students, and patients alike. Some well-known examples of medical encyclopedias include the Merck Manual and the Stedman's Medical Dictionary.

Prenatal ultrasonography, also known as obstetric ultrasound, is a medical diagnostic procedure that uses high-frequency sound waves to create images of the developing fetus, placenta, and amniotic fluid inside the uterus. It is a non-invasive and painless test that is widely used during pregnancy to monitor the growth and development of the fetus, detect any potential abnormalities or complications, and determine the due date.

During the procedure, a transducer (a small handheld device) is placed on the mother's abdomen and moved around to capture images from different angles. The sound waves travel through the mother's body and bounce back off the fetus, producing echoes that are then converted into electrical signals and displayed as images on a screen.

Prenatal ultrasonography can be performed at various stages of pregnancy, including early pregnancy to confirm the pregnancy and detect the number of fetuses, mid-pregnancy to assess the growth and development of the fetus, and late pregnancy to evaluate the position of the fetus and determine if it is head down or breech. It can also be used to guide invasive procedures such as amniocentesis or chorionic villus sampling.

Overall, prenatal ultrasonography is a valuable tool in modern obstetrics that helps ensure the health and well-being of both the mother and the developing fetus.

Trophoblasts are specialized cells that make up the outer layer of a blastocyst, which is a hollow ball of cells that forms in the earliest stages of embryonic development. In humans, this process occurs about 5-6 days after fertilization. The blastocyst consists of an inner cell mass (which will eventually become the embryo) and an outer layer of trophoblasts.

Trophoblasts play a crucial role in implantation, which is the process by which the blastocyst attaches to and invades the lining of the uterus. Once implanted, the trophoblasts differentiate into two main layers: the cytotrophoblasts (which are closer to the inner cell mass) and the syncytiotrophoblasts (which form a multinucleated layer that is in direct contact with the maternal tissues).

The cytotrophoblasts proliferate and fuse to form the syncytiotrophoblasts, which have several important functions. They secrete enzymes that help to degrade and remodel the extracellular matrix of the uterine lining, allowing the blastocyst to implant more deeply. They also form a barrier between the maternal and fetal tissues, helping to protect the developing embryo from the mother's immune system.

Additionally, trophoblasts are responsible for the formation of the placenta, which provides nutrients and oxygen to the developing fetus and removes waste products. The syncytiotrophoblasts in particular play a key role in this process by secreting hormones such as human chorionic gonadotropin (hCG), which helps to maintain pregnancy, and by forming blood vessels that allow for the exchange of nutrients and waste between the mother and fetus.

Abnormalities in trophoblast development or function can lead to a variety of pregnancy-related complications, including preeclampsia, intrauterine growth restriction, and gestational trophoblastic diseases such as hydatidiform moles and choriocarcinomas.

This was a first step away from in-vivo pregnancy testing and initiated a series of improvements in pregnancy testing leading ... A Thin Blue Line: The History of the Pregnancy Test Kit. "A Timeline of Pregnancy Testing". National Institutes of Health. ... but not for its usage as a functional pregnancy test. Hormonal pregnancy tests such as Primodos and Duogynon were used in the ... and typically clinicians will diagnose a positive pregnancy test at 5mIU/mL. There is a multilevel urine pregnancy test (MLPT) ...
She will be offered HIV testing at all stages of her pregnancy in case she changes her mind. The most updated HIV testing ... If this test is positive, the CDC recommends performing follow-up testing using a test called the HIV-1/HIV-2 antibody ... Opt-out testing involves educating the patient on the impact of an HIV infection on pregnancy, notifying the patient that HIV ... The following monitoring tests are recommended for women who are diagnosed with HIV prior to or during pregnancy: HIV Viral ...
In 2012 Delhi Charter School was made to drop its school ban on pregnant students and the ability to mandate pregnancy tests ... "School's policy requires girls to take pregnancy tests". Today.msnbc.msn.com. Archived from the original on 2012-08-08. ... Yarrow, Allison (8 August 2012). "Louisiana Charter School Mandates Pregnancy Tests For 'Suspect' Students". The Daily Beast. ... "The relationship between education and teen pregnancy works both ways. That is, teen pregnancy often has a negative impact on ...
Tests during pregnancy). ... a commercial test known as the PartoSure test was developed and ... and fetal fibronectin testing (fFN) via a commercially available, rapid test. Furthermore, the authors suggested that the ... correlation between the two tests and led the investigators to propose the use of the noninvasive PAMG-1 test in situations ... Premature rupture of fetal membranes (or PROM as it is more commonly referred) occurs in roughly 10% of pregnancies and is one ...
Pregnancy test Lab. Labor Lab. Childbed Lab. Newborn baby Lab. Biomedicine Lab. Medical records Lab. Skill Medical Record Lab. ... Computer Based Test Hot Spot (Wifi) Sports include table tennis, futsal, badminton, volleyball, basketball. Art: Band, choir ...
To validate the outcome, pregnancy tests can be taken ten days or more, after the event. If one does become pregnant due to ... Cleveland Clinic (2017). "Pregnancy Test Information". Cleveland Clinic. Retrieved 2021-03-31. Krug, Etienne G.; WHO (2002). ... Immediate and selective testing is recommended for individuals who opt to receive a medical examination after the event to ... If the individual proceeds with the pregnancy, they can decide whether to place the child up for adoption or raise the child ...
Also, this test requires a smaller volume of blood compared to a pH estimation. During pregnancy, placental gas-exchange is ... Fetal blood sampling is a complex procedure and performed when other tests are not possible. It can be done for pregnancies ... Young C, Ryce A (2018). Fetal Scalp Lactate Testing During Intrapartum Pregnancy with Abnormal Fetal Heart Rate: A Review of ... Therefore, due to limitation in adding value, fetal scalp testing can serve as second line test to provide and strengthen the ...
"UK pregnancy test drug Primodos used for abortions in Germany". "Hormone pregnancy tests". Medicines and Healthcare products ... The expert group recommended that families who took a hormone pregnancy test and experienced "an adverse pregnancy outcome" ... Another hormonal pregnancy test called Duogynon was in use in Germany during the same general time period. In the 1960s, Dr. ... Primodos was a hormone-based pregnancy test used in the 1960s and 1970s that consisted of two pills that contained ...
Vaginal bleeding during pregnancy being misinterpreted as a period. False negative pregnancy tests. The series is shown on ... Believing they were infertile, and thus not considering pregnancy a possible cause of symptoms. Not having any of the " ... Frequent reasons for the subjects not recognizing pregnancy include: Mistaking the symptoms for another condition or illness. ... featuring women who have had two surprise pregnancies. "Mike Mathis Productions". Retrieved 18 April 2016. "Unsuspecting Women ...
From the 1930s to the 1950s, thousands of frogs were exported across the world for use in these pregnancy tests. The National ... This led to a pregnancy test that was later refined by South African researchers Hillel Abbe Shapiro and Harry Zwarenstein. A ... Elkan ER (December 1938). "The Xenopus Pregnancy Test". British Medical Journal. 2 (4067): 1253-1274.2. doi:10.1136/bmj.2.4067. ... Four years after the first Xenopus test, Zwarenstein's colleague, Dr Louis Bosman, reported that the test was accurate in more ...
He is known for the development of the rabbit test, a pregnancy test developed in 1931 while he was teaching at the Perelman ... Maurice Friedman, 87, Dies; Created 'Rabbit' Pregnancy Test". The New York Times. p. 32. Retrieved December 4, 2022. (Use mdy ... "Maurice Friedman, "rabbit test" doctor". Tampa Bay Times. March 10, 1991. Retrieved December 4, 2022. Howe, Marvine (March 10, ... Rapid Procedure for the Laboratory Diagnosis of Early Pregnancies". American Journal of Obstetrics and Gynecology. 21 (3): 405- ...
... a first step away from in-vivo pregnancy testing. This test initiated a series of improvements in pregnancy testing leading to ... Wide, L; Gemzell, C. A. (1960). "An immunological pregnancy test". Acta Endocrinologica. 35: 261-7. doi:10.1530/acta.0.xxxv0261 ... In 1960 Gemzell and Leif Wide presented a pregnancy test based on in-vitro hemagglutination inhibition, ... 1958, First report using pituitary FSH 1960, "An immunological pregnancy test" 1962, "Induction of ovulation with human ...
Michetti F, Gazzolo D (2004). "S100B testing in pregnancy". Clin. Chim. Acta. 335 (1-2): 1-7. doi:10.1016/S0009-8981(03)00243-2 ... Twenty three tests were carried out on mutant mice, but no significant abnormalities have yet been observed. S100B has been ... An extremely important application of serum S100B testing is in the selection of patients with minor head injury who do not ...
Electroencephalography, Tests during pregnancy). ... and fetuses in the last trimester of pregnancy. The doctors ... temporarily preserved tiny unborn fetuses removed during ectopic pregnancies and recorded from their brains. The team used ...
... is preferred for tests like urinalysis and pregnancy screening because it is typically more concentrated, making the test more ... Simple point-of-care tests can detect pregnancy by identifying the presence of beta-hCG in the urine and indicate the use of ... A urine test is any medical test performed on a urine specimen. The analysis of urine is a valuable diagnostic tool because its ... and urine pregnancy testing. The value of urine for diagnostic purposes has been recognized since ancient times. Urine ...
"A Timeline of Pregnancy Testing". A Thin Blue Line: The History of the Pregnancy Test Kit. Retrieved 13 March 2015. Haliski, ... Their method, far more sensitive than existing hCG tests, became the basis for the first home pregnancy tests, which hit the ... "hCG Research at NIH, page 4". A Thin Blue Line: The History of the Pregnancy Test Kit. Office of NIH History. Retrieved 13 ... "hCG Research at NIH". A Thin Blue Line: The History of the Pregnancy Test Kit. Office of NIH History. Retrieved 13 March 2015 ...
"Cervical mucus testing - Pregnancy Info". www.pregnancyinfo.ca. Retrieved 2021-09-20. Health, Center for Devices and ... This test can be used in multiple ways. A few drops of urine can be added to the test device tip. Alternatively, the test ... Fertility testing for men involves semen testing and genetic testing, as other factors such as impotence are obvious. Semen can ... The clomifene citrate challenge test is similar to cycle-day-three FSH testing. To perform this test blood samples are taken on ...
It was the world's first "rapid home test" that gave pregnancy test results in 30 minutes and allowed a woman to take a test ... In 1988, Clearblue launched the first one-step pregnancy test with the invention of lateral flow technology. This one-step test ... "A Timeline of Pregnancy Testing". The Office of NIH History. Retrieved 2020-12-11 Whitelaw, Dr. W. A., ed. (2004). "History of ... "A Timeline of Pregnancy Testing". The Office of NIH History. Archived from the original on 2019-08-07. Retrieved 2013-10-07. ...
Many home pregnancy tests are immunoassays, which detect the pregnancy marker human chorionic gonadotropin. Other clinical ... Butler, SA (2001). "Detection of early pregnancy forms of human chorionic gonadotropin by home pregnancy test devices". ... "ELISA for Home Pregnancy Test". Archived from the original on 21 September 2017. Retrieved 11 December 2012. ... An immunoassay (IA) is a biochemical test that measures the presence or concentration of a macromolecule or a small molecule in ...
Blood pregnancy tests are more sensitive than urine tests (giving fewer false negatives). Home pregnancy tests are urine tests ... Couvade syndrome Cryptic pregnancy False pregnancy Simulated pregnancy Pregnancy-related anxiety "What are some common signs of ... The beginning of pregnancy may be detected either based on symptoms by the woman herself, or by using pregnancy tests. However ... Pregnancy may be confirmed with a pregnancy test. Methods of birth control-or, more accurately, contraception-are used to avoid ...
Abderhalden is known for a blood test for pregnancy, a test for cystine in urine, and for explaining the Abderhalden-Kaufmann- ... The pregnancy test was determined to be unreliable a few years after its inception. In late 1912 Abderhalden's "defensive ... doi:10.1016/S0021-9258(18)87625-6. (experimental evidence of the unreliability of the Abderhalden pregnancy test) Noll, R. ( ... Michaelis, L.; von Lagermarck, L. (1914). "Die Abderhaldensche Schwangerschaftsdiagnose" [Abderhalden's pregnancy test]. Dtsch ...
Class 2 - Devices with a higher risk than Class 1. For example, condoms and pregnancy tests. Class 3 - Devices with a very high ... This means that the FDA will not test them itself. In those instances where a device is substantially equivalent to an existing ...
"Why couldn't Joanna Jedrzejczyk fight last minute at UFC 213? 'It was about a pregnancy test'". MMAjunkie. 2017-07-09. ... Nunes tested positive for COVID-19 on July 29 and the bout was cancelled. The fight was rescheduled and eventually took place ... "Nunes tests positive; title defense vs. Pena off". ESPN. 2021-07-29. Retrieved 2021-07-29. "Amanda Nunes' positive COVID-19 ... test scraps UFC 265 title defense". MMA Junkie. 2021-07-29. Retrieved 2021-07-29. Jamal Boussenaf (2021-08-30). "Amanda Nunes ...
... pregnancy testing and pregnancy options counseling; prenatal care; testing and treatment for sexually transmitted infections; ... over one million pregnancy tests and prenatal services, over 324,000 abortion services, and over 100,000 other services, for a ... "Birth Control for Men , How Can Men Prevent Pregnancy?". www.plannedparenthood.org. Archived from the original on March 6, 2017 ... Services for men's health include STD testing and treatment, vasectomy procedures, and erectile dysfunction services. Education ...
"Ectopic Pregnancy: Symptoms, Causes, Treatments & Tests". Cleveland Clinic. Retrieved 2022-04-23. Janssen, E. B.; Rijkers, A. C ... Related to pregnancy Pelvic girdle pain Ectopic pregnancy-a pregnancy implanted outside the uterus. Gynecologic (from more ... In chronic pelvic pain, there are no standard diagnostic tests in males; diagnosis is by exclusion of other disease entities. ... Pelvic girth pain is frequent during pregnancy. Issues have been found in current procedures for the treatment of chronic ...
In 1914 he published a paper suggesting that Emil Abderhalden's notorious pregnancy tests could not be reproduced, a paper ... Abderhalden's pregnancy test]. Dtsch. Med. Wochenschr. 7 (1): 316-319. doi:10.1055/s-0029-1190182. Michaelis, L. (1925). " ...
Hodgson JE (1955). "Use of hyaluronidase in the frog test for pregnancy". Am. J. Clin. Pathol. 25 (9): 1096-8. doi:10.1093/ajcp ... Her early research included pregnancy-testing methods and in 1952 she became a Founding Fellow of American College of ... Hodgson JE (1953). "Office use of the frog test for pregnancy". Journal of the American Medical Association. 153 (4): 271-4. ... ISBN 978-0-520-20256-6. Hodgson JE, Taguchi R (1950). "The Rana pipiens frog test for pregnancy". Minnesota Medicine. 33 (12): ...
"Philly startup creates new pregnancy test". Philly.com. Retrieved 2017-08-11. "Unapologetically Pink". FacesOfFounders.com. ... which produces a flushable pregnancy test), Intuitap (which has a medical device aimed to streamline the spinal tap procedure ...
Pregnancy tests using frogs". old.qi.com. Retrieved 2018-09-08. Mainini, Carlos Galli (1947). "Pregnancy test using the male ... Xenopus laevis is also notable for its use in the first widely used method of pregnancy testing. In the 1930s, two South ... "Doctors Used to Use Live African Frogs As Pregnancy Tests". Smithsonian Magazine. "QI Talk Forum , View topic - Flora and Fauna ... Shapiro, Hillel A.; Zwarenstein, Harry (March 1935). "A test for the early diagnosis of pregnancy". South African Medical ...
Her column, "Who Made That," detailed the origins of a wide variety of things, such as the cubicle and the home pregnancy test ... Kennedy, Pagan (2012-07-27). "Who Made That Home Pregnancy Test?". The New York Times. Retrieved 2013-09-10. Kennedy, Pagan ( ...

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