Potassium Iodide
Sporotrichosis
Iodine
Goiter
Potassium
Methimazole
Thyroid Gland
Thyroxine
Molecular cloning and expression of adenosine kinase from Leishmania donovani: identification of unconventional P-loop motif. (1/166)
The unique catalytic characteristics of adenosine kinase (Adk) and its stage-specific differential activity pattern have made this enzyme a prospective target for chemotherapeutic manipulation in the purine-auxotrophic parasitic protozoan Leishmania donovani. However, nothing is known about the structure of the parasite Adk. We report here the cloning of its gene and the characterization of the gene product. The encoded protein, consisting of 345 amino acid residues with a calculated molecular mass of 37173 Da, shares limited but significant similarity with sugar kinases and inosine-guanosine kinase of microbial origin, supporting the notion that these enzymes might have the same ancestral origin. The identity of the parasite enzyme with the corresponding enzyme from two other sources so far described was only 40%. Furthermore, 5' RNA mapping studies indicated that the Adk gene transcript is matured post-transcriptionally with the trans-splicing of the mini-exon (spliced leader) occurring at nt -160 from the predicted translation initiation site. The biochemical properties of the recombinant enzyme were similar to those of the enzyme isolated from leishmanial cells. The intrinsic tryptophan fluorescence of the enzyme was substrate-sensitive. On the basis of a multiple protein-alignment sequence comparison and ATP-induced fluorescence quenching in the presence or the absence of KI and acrylamide, the docking site for ATP has been provisionally identified and shown to have marked divergence from the consensus P-loop motif reported for ATP- or GTP-binding proteins from other sources. (+info)Antagonistic effect of ganglioside GM1 and GM3 on the activity and conformation of sarcoplasmic reticulum Ca(2+)-ATPase. (2/166)
It was found that rabbit skeletal muscle sarcoplasmic reticulum (SR) contained two main gangliosides: NeuNAc alpha 2-->3 Gal beta 1-->4 Glc beta 1-->1'ceramide (GM3) and Gal beta 1-->3 GalNAc beta 1-->4(NeuNAc alpha 2-->3) Gal beta 1-->4 Glc beta 1-->1'ceramide (GM1), and that the most abundant ganglioside GM3 could positively modulate the SR Ca(2+)-ATPase activity. In this paper, the effect of GM1 on Ca(2+)-ATPase was further investigated and compared with that of GM3. The study demonstrates that GM1 has an opposite effect with respect to GM3 on the activity of SR Ca(2+)-ATPase. Using assays, including intrinsic and time-resolved fluorescence and fluorescence quenching, the conformational changes of SR Ca(2+)-ATPase induced by GM1 and GM3 were compared. Obtained results indicate that GM1 could make the Ca(2+)-ATPase molecules less compact in the hydrophilic domain but more compact in the hydrophobic domain, while GM3 makes the enzyme more compact in both the hydrophilic and hydrophobic domain. Homogeneous GM1 and GM3 with the same ceramide moiety had similar effects on SR Ca(2+)-ATPase activities compared to their natural counterparts, suggesting that the carbohydrate chain may be the key moiety of the ganglioside molecule to be responsible for the difference of the effect on enzyme activity. (+info)Subunit interactions in the clathrin-coated vesicle vacuolar (H(+))-ATPase complex. (3/166)
The vacuolar (H(+))-ATPases (or V-ATPases) are structurally related to the F(1)F(0) ATP synthases of mitochondria, chloroplasts and bacteria, being composed of a peripheral (V(1)) and an integral (V(0)) domain. To further investigate the arrangement of subunits in the V-ATPase complex, covalent cross-linking has been carried out on the V-ATPase from clathrin-coated vesicles using three different cross-linking reagents. Cross-linked products were identified by molecular weight and by Western blot analysis using polyclonal antibodies raised against individual V-ATPase subunits. In the intact V(1)V(0) complex, evidence for cross-linking of subunits C and E, D and F, as well as E and G by disuccinimidyl glutarate was obtained, while in the free V(1) domain, cross-linking of subunits H and E was also observed. Subunits C and E as well as D and E could be cross-linked by 1-ethyl-3-(dimethylaminopropyl)carbodiimide, while subunits a and E could be cross-linked by 4-(N-maleimido)benzophenone. It was further demonstrated that it is possible to treat the V-ATPase with potassium iodide and MgATP in such a way that while subunits A, B, and H are nearly quantitatively removed, significant amounts of subunits C, D, E, and F remain attached to the membrane, suggesting that one or more of these latter subunits are in contact with the V(0) domain. In addition, treatment of the V-ATPase with cystine, which modifies Cys-254 of the catalytic A subunit, results in dissociation of subunit H, suggesting communication between the catalytic nucleotide binding site and subunit H. Finally, the stoichiometry of subunits F, G, and H were determined by quantitative amino acid analysis. Based on these and previous observations, a new structural model of the V-ATPase from clathrin-coated vesicles is proposed. (+info)Photoaffinity labeling of wild-type and mutant forms of the yeast V-ATPase A subunit by 2-azido-[(32)P]ADP. (4/166)
Molecular modeling studies have previously suggested the possible presence of four aromatic residues (Phe(452), Tyr(532), Tyr(535), and Phe(538)) near the adenine binding pocket of the catalytic site on the yeast V-ATPase A subunit (MacLeod, K. J., Vasilyeva, E., Baleja, J. D., and Forgac, M. (1998) J. Biol. Chem. 273, 150-156). To test the proximity of these aromatic residues to the adenine ring, the yeast V-ATPase containing wild-type and mutant forms of the A subunit was reacted with 2-azido-[(32)P]ADP, a photoaffinity analog that stably modifies tyrosine but not phenylalanine residues. Mutant forms of the A subunit were constructed in which the two endogenous tyrosine residues were replaced with phenylalanine and in which a single tyrosine was introduced at each of the four positions. Strong ATP-protectable labeling of the A subunit was observed for the wild-type and the mutant containing tyrosine at 532, significant ATP-protectable labeling was observed for the mutants containing tyrosine at positions 452 and 538, and only very weak labeling was observed for the mutants containing tyrosine at 535 or in which all four residues were phenylalanine. These results suggest that Tyr(532) and possibly Phe(452) and Tyr(538) are in close proximity to the adenine ring of ATP bound to the A subunit. In addition, the effects of mutations at Phe(452), Tyr(532), Tyr(535), and Glu(286) on dissociation of the peripheral V(1) and integral V(0) domains both in vivo and in vitro were examined. The results suggest that in vivo dissociation requires catalytic activity while in vitro dissociation requires nucleotide binding to the catalytic site. (+info)The D-loop structure of human mtDNA is destabilized directly by 1-methyl-4-phenylpyridinium ion (MPP+), a parkinsonism-causing toxin. (5/166)
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine has been reported to cause parkinsonism via its neurotoxic form, 1-methyl-4-phenylpyridinium ion (MPP+), which inhibits complex I of the mitochondrial respiratory chain. Its parkinsonism-causing mechanisms attract a great deal of interest as a model of the disease. Recently, we reported that MPP+ strongly decreases the amount of mtDNA independent of the inhibition of complex I. Maintenance of a proper amount of mtDNA is essential for the normal function of mitochondria as exemplified in many mitochondrial diseases. The most characteristic feature in vertebral mtDNA replication is that H-strand synthesis proceeds displacing the parental H-strand as a long single strand. It forms the D-loop, a triplex replication intermediate composed of the parental L-strand, nascent H-strand and displaced H-strand. Here we show that MPP+ does not inhibit DNA synthesis by DNA polymerase gamma, but rather releases the nascent H-strands from mtDNA both in organello and in vitro. This indicates that MPP+ directly destabilizes the D-loop structure, thereby inhibiting replication. This study raises a new mechanism, i.e. destabilization of replication intermediates, for depletion of mtDNA. (+info)Sporotrichosis in Peru: description of an area of hyperendemicity. (6/166)
Sporotrichosis is a sporadic and rare mycotic infection in most of the developed world. In many parts of the developing world, sporotrichosis is much more commonly recognized, but epidemiological data are generally lacking from these regions. We report epidemiological, clinical, and treatment data from 238 cases of culture-proven sporotrichosis occurring in a relatively remote area of the south central highlands of Peru that were retrospectively collected during 1995-1997. Most cases (60%) occurred in children aged +info)Dynamics at Lys-553 of the acto-myosin interface in the weakly and strongly bound states. (7/166)
Lys-553 of skeletal muscle myosin subfragment 1 (S1) was specifically labeled with the fluorescent probe FHS (6-[fluorescein-5(and 6)-carboxamido]hexanoic acid succinimidyl ester) and fluorescence quenching experiments were carried out to determine the accessibility of this probe at Lys-553 in both the strongly and weakly actin-bound states of the MgATPase cycle. Solvent quenchers of varying charge [nitromethane, (2,2,6, 6-tetramethyl-1-piperinyloxy) (TEMPO), iodide (I(-)), and thallium (Tl(+))] were used to assess both the steric and electrostatic accessibilities of the FHS probe at Lys-553. In the strongly bound rigor (nucleotide-free) and MgADP states, actin offered no protection from solvent quenching of FHS by nitromethane, TEMPO, or thallium, but did decrease the Stern-Volmer constant by almost a factor of two when iodide was used as the quencher. The protection from iodide quenching was almost fully reversed with the addition of 150 mM KCl, suggesting this effect is ionic in nature rather than steric. Conversely, actin offered no protection from iodide quenching at low ionic strength during steady-state ATP hydrolysis, even with a significant fraction of the myosin heads bound to actin. Thus, the lower 50 kD subdomain of myosin containing Lys-553 appears to interact differently with actin in the weakly and strongly bound states. (+info)Detection of fluorescently labeled actin-bound cross-bridges in actively contracting myofibrils. (8/166)
Myosin subfragment 1 (S1) can be specifically modified at Lys-553 with the fluorescent probe FHS (6-[fluorescein-5(and 6)-carboxamido]hexanoic acid succinimidyl ester) (Bertrand, R., J. Derancourt, and R. Kassab. 1995. Biochemistry. 34:9500-9507), and solvent quenching of FHS-S1 with iodide has been shown to be sensitive to actin binding at low ionic strength (MacLean, Chrin, and Berger, 2000. Biophys. J. 000-000). In order to extend these results and examine the fraction of actin-bound myosin heads within the myofilament lattice during calcium activation, we have modified skeletal muscle myofibrils, mildly cross-linked with EDC (1-ethyl-3-[3-(dimethylamino)propyl]carbodiimide) to prevent shortening, with FHS. The myosin heavy chain appears to be the predominant site of labeling, and the iodide quenching patterns are consistent with those obtained for myosin S1 in solution, suggesting that Lys-553 is indeed the primary site of FHS incorporation in skeletal muscle myofibrils. The iodide quenching results from calcium-activated FHS-myofibrils indicate that during isometric contraction 29% of the myosin heads are strongly bound to actin within the myofilament lattice at low ionic strength. These results suggest that myosin can be specifically modified with FHS in more complex and physiologically relevant preparations, allowing the real time examination of cross-bridge interactions with actin in in vitro motility assays and during isometric and isotonic contractions within single muscle fibers. (+info)Potassium iodide is an inorganic, non-radioactive salt of iodine. Medically, it is used as a thyroid blocking agent to prevent the absorption of radioactive iodine in the event of a nuclear accident or radiation exposure. It works by saturating the thyroid gland with stable iodide, which then prevents the uptake of radioactive iodine. This can help reduce the risk of thyroid cancer and other thyroid related issues that may arise from exposure to radioactive materials. Potassium iodide is also used in the treatment of iodine deficiency disorders.
Iodides are chemical compounds that contain iodine in the form of an iodide ion (I-). Iodide ions are negatively charged ions that consist of one iodine atom and an extra electron. Iodides are commonly found in dietary supplements and medications, and they are often used to treat or prevent iodine deficiency. They can also be used as expectorants to help thin and loosen mucus in the respiratory tract. Examples of iodides include potassium iodide (KI) and sodium iodide (NaI).
Sporotrichosis is a fungal infection caused by the dimorphic fungus Sporothrix schenckii. It primarily affects the skin and subcutaneous tissues, although it can rarely disseminate to other organs in immunocompromised individuals. The infection often occurs after traumatic inoculation of the fungus through cuts or abrasions in the skin, particularly in people who work with plant materials like sphagnum moss, rose bushes, or hay.
The disease presents in three main clinical forms: cutaneous, lymphocutaneous, and disseminated. The cutaneous form involves a single ulcerating or verrucous lesion at the site of inoculation. The lymphocutaneous form is characterized by the spread of the infection along the lymphatic channels, resulting in a chain of nodular or ulcerative lesions. Disseminated sporotrichosis occurs when the infection spreads hematogenously to various organs, primarily affecting immunocompromised individuals and causing severe, life-threatening manifestations.
Diagnosis typically involves direct examination and culture of clinical specimens, as well as serological tests and molecular techniques like PCR. Treatment usually consists of systemic antifungal therapy with itraconazole or posaconazole, although amphotericin B may be required in severe cases or for disseminated infection.
Iodine is an essential trace element that is necessary for the production of thyroid hormones in the body. These hormones play crucial roles in various bodily functions, including growth and development, metabolism, and brain development during pregnancy and infancy. Iodine can be found in various foods such as seaweed, dairy products, and iodized salt. In a medical context, iodine is also used as an antiseptic to disinfect surfaces, wounds, and skin infections due to its ability to kill bacteria, viruses, and fungi.
Goiter is a medical term that refers to an enlarged thyroid gland. The thyroid gland is a small, butterfly-shaped gland located in the front of your neck below the larynx or voice box. It produces hormones that regulate your body's metabolism, growth, and development.
Goiter can vary in size and may be visible as a swelling at the base of the neck. It can be caused by several factors, including iodine deficiency, autoimmune disorders, thyroid cancer, pregnancy, or the use of certain medications. Depending on the underlying cause and the severity of the goiter, treatment options may include medication, surgery, or radioactive iodine therapy.
Potassium is a essential mineral and an important electrolyte that is widely distributed in the human body. The majority of potassium in the body (approximately 98%) is found within cells, with the remaining 2% present in blood serum and other bodily fluids. Potassium plays a crucial role in various physiological processes, including:
1. Regulation of fluid balance and maintenance of normal blood pressure through its effects on vascular tone and sodium excretion.
2. Facilitation of nerve impulse transmission and muscle contraction by participating in the generation and propagation of action potentials.
3. Protein synthesis, enzyme activation, and glycogen metabolism.
4. Regulation of acid-base balance through its role in buffering systems.
The normal serum potassium concentration ranges from 3.5 to 5.0 mEq/L (milliequivalents per liter) or mmol/L (millimoles per liter). Potassium levels outside this range can have significant clinical consequences, with both hypokalemia (low potassium levels) and hyperkalemia (high potassium levels) potentially leading to serious complications such as cardiac arrhythmias, muscle weakness, and respiratory failure.
Potassium is primarily obtained through the diet, with rich sources including fruits (e.g., bananas, oranges, and apricots), vegetables (e.g., leafy greens, potatoes, and tomatoes), legumes, nuts, dairy products, and meat. In cases of deficiency or increased needs, potassium supplements may be recommended under the guidance of a healthcare professional.
Methimazole is an anti-thyroid medication that is primarily used to treat hyperthyroidism, a condition in which the thyroid gland produces excessive amounts of thyroid hormones. It works by inhibiting the enzyme thyroperoxidase, which is essential for the production of thyroid hormones. By blocking this enzyme, methimazole reduces the amount of thyroid hormones produced by the thyroid gland, helping to restore normal thyroid function.
Methimazole is available in oral tablet form and is typically taken two to three times a day. Common side effects of methimazole include nausea, vomiting, skin rashes, and joint pain. In rare cases, it can cause more serious side effects such as liver damage or agranulocytosis (a severe decrease in white blood cell count).
It is important to note that methimazole should only be used under the close supervision of a healthcare provider, as regular monitoring of thyroid function and potential side effects is necessary. Additionally, it may take several weeks or months of treatment with methimazole before thyroid function returns to normal.
Thyroid diseases are a group of conditions that affect the function and structure of the thyroid gland, a small butterfly-shaped endocrine gland located in the base of the neck. The thyroid gland produces hormones that regulate many vital functions in the body, including metabolism, growth, and development.
Thyroid diseases can be classified into two main categories: hypothyroidism and hyperthyroidism. Hypothyroidism occurs when the thyroid gland does not produce enough hormones, leading to symptoms such as fatigue, weight gain, cold intolerance, constipation, and depression. Hyperthyroidism, on the other hand, occurs when the thyroid gland produces too much hormone, resulting in symptoms such as weight loss, heat intolerance, rapid heart rate, tremors, and anxiety.
Other common thyroid diseases include:
1. Goiter: an enlargement of the thyroid gland that can be caused by iodine deficiency or autoimmune disorders.
2. Thyroid nodules: abnormal growths on the thyroid gland that can be benign or malignant.
3. Thyroid cancer: a malignant tumor of the thyroid gland that requires medical treatment.
4. Hashimoto's disease: an autoimmune disorder that causes chronic inflammation of the thyroid gland, leading to hypothyroidism.
5. Graves' disease: an autoimmune disorder that causes hyperthyroidism and can also lead to eye problems and skin changes.
Thyroid diseases are diagnosed through a combination of physical examination, medical history, blood tests, and imaging studies such as ultrasound or CT scan. Treatment options depend on the specific type and severity of the disease and may include medication, surgery, or radioactive iodine therapy.
The thyroid gland is a major endocrine gland located in the neck, anterior to the trachea and extends from the lower third of the Adams apple to the suprasternal notch. It has two lateral lobes, connected by an isthmus, and sometimes a pyramidal lobe. This gland plays a crucial role in the metabolism, growth, and development of the human body through the production of thyroid hormones (triiodothyronine/T3 and thyroxine/T4) and calcitonin. The thyroid hormones regulate body temperature, heart rate, and the production of protein, while calcitonin helps in controlling calcium levels in the blood. The function of the thyroid gland is controlled by the hypothalamus and pituitary gland through the thyroid-stimulating hormone (TSH).
Thyroxine (T4) is a type of hormone produced and released by the thyroid gland, a small butterfly-shaped endocrine gland located in the front of your neck. It is one of two major hormones produced by the thyroid gland, with the other being triiodothyronine (T3).
Thyroxine plays a crucial role in regulating various metabolic processes in the body, including growth, development, and energy expenditure. Specifically, T4 helps to control the rate at which your body burns calories for energy, regulates protein, fat, and carbohydrate metabolism, and influences the body's sensitivity to other hormones.
T4 is produced by combining iodine and tyrosine, an amino acid found in many foods. Once produced, T4 circulates in the bloodstream and gets converted into its active form, T3, in various tissues throughout the body. Thyroxine has a longer half-life than T3, which means it remains active in the body for a more extended period.
Abnormal levels of thyroxine can lead to various medical conditions, such as hypothyroidism (underactive thyroid) or hyperthyroidism (overactive thyroid). These conditions can cause a range of symptoms, including weight gain or loss, fatigue, mood changes, and changes in heart rate and blood pressure.
Tablets30
- But many residents are still preparing, buying up dried foods, 72-hour survival kits and bottles of kelp tablets, potassium iodide and seaweed. (mv-voice.com)
- These actions include sheltering, evacuation, and the use of potassium iodide tablets when appropriate. (calverthealth.org)
- If you live within the emergency protective zone of Calvert Cliffs nuclear power plant, you are eligible to receive a supply of potassium iodide tablets to have on hand in the unlikely event of a radiation emergency. (calverthealth.org)
- Schools within the Calvert Cliffs nuclear power plant emergency protective zone have a supply of potassium iodide tablets on hand for staff and students. (calverthealth.org)
- Nursing homes within the emergency protective zone have a supply of potassium iodide tablets on hand for residents and staff. (calverthealth.org)
- In the unlikely event of a radiation emergency potassium iodide tablets, if taken properly, will reduce the dose of radiation to the thyroid gland from radioactive iodide and reduce the risk of thyroid cancer. (calverthealth.org)
- Potassium iodide tablets are used to supplement other protective actions such as evacuation or sheltering in place. (calverthealth.org)
- How can I obtain potassium iodide tablets? (calverthealth.org)
- Calvert residents who live within a 10-mile radius (the emergency protective zone) of Calvert Cliffs nuclear power plant can receive potassium iodide tablets free-of-charge from the Calvert County Health Department. (calverthealth.org)
- Potassium iodide tablets may be picked up at the health department Monday through Friday, 8:30 a.m. - 4:00 p.m. (calverthealth.org)
- If you don't live in the emergency protective zone but want to purchase potassium iodide tablets, contact your local pharmacist. (calverthealth.org)
- A prescription is not required to purchase potassium iodide tablets. (calverthealth.org)
- Similar use as potassium iodate tablets, ki pills or other iodine supplements. (readymaderesources.com)
- GUARANTEED PURE - Our Potassium Iodine Drops, potassium iodide tablets, and potassium iodine pills are 3rd party tested and produced in the USA in an FDA-registered Food-Grade Facility. (readymaderesources.com)
- IOSAT Tablets (Potassium Iodide Tablets, U.S.P.): packages of 14 tablets (NDC51803-001-01): Each white, round, scored tablet contains 130 mg. potassium iodide. (directive21.com)
- Be the first to review "iOSAT Potassium Iodide 14 Tablets, 130 mg - In Stock! (directive21.com)
- Nature's Plus Potassium Iodide Tablets are an all-natural formulation. (arnoldsupplements.com)
- I tried Potassium Iodide Tablets to supplement my vegan diet, I do not like like the taste of kelp and I was worried about the arsenic found in some kelp products, I was so glad I tried this product it is great, try it you wont be disappointed. (arnoldsupplements.com)
- A search of the FedBizOpps website returns no other results regarding the purchase of potassium iodide from any government agency, suggesting that the DHHS bulk buy of the tablets is unprecedented in recent times. (nowtheendbegins.com)
- One such protective measure is the use of potassium iodide tablets. (buckhorncliffs.com)
- This is where potassium iodide (KI) tablets come into play. (buckhorncliffs.com)
- Among the various brands available, ThyroShield Potassium Iodide Tablets stand out for their quality and efficacy. (buckhorncliffs.com)
- Potassium iodide (KI) comes in 130mg tablets , 65mg tablets , and an oral solution that contains 65mg/ml. (urbansurvivalsite.com)
- Protect yourself from hazardous nuclear radiation by stocking up on our Potassium Iodide tablets. (peteprepstore.com)
- Each factory-sealed bottle of our Potassium Iodide contains 60 tablets. (peteprepstore.com)
- Harrisburg - The Department of Health will provide free potassium iodide tablets Thursday, Aug. 8, to Pennsylvanians who live, work or attend school within a 10-mile radius of one of the state's five nuclear power plants. (westmayfieldborough.us)
- For Potassium iodide Jodetten 150 Henning tablets 100 pc information on risks and side effects, read the package insert and ask your doctor or pharmacist. (eliveragroup.com)
- NOW Foods Potassium Iodide 30mg (60 tablets) is a compound containing iodine. (bono.shop)
- These Potassium Iodide Tablets are intended for short term use, and only when directed to do so by an official health warning. (nutrigeek.shop)
- 130 mg potassium iodide (2 tablets) once daily. (medscape.co.uk)
SSKI4
- Saturated Solution of Potassium Iodide (SSKI or Lugol's Solution) is not an FDA-approved drug. (cdc.gov)
- The dose typically begins with a loading dose, then 1/3 mL SSKI (5 drops or 250 mg iodine as iodide), three times per day. (nutrawiki.org)
- Iodide solutions made from a few drops of SSKI added to drinks have also been used as expectorants to increase the water content of respiratory secretions and encourage effective coughing. (nutrawiki.org)
- Various iodide preparations, including strong iodine solution (ie, Lugol solution), SSKI, and iodinated radiographic contrast agents (sodium ipodate) have been used. (medscape.com)
Supply of potassium iodide1
- Under current regulations , states with populations living within 10 miles of a nuclear plant are encouraged, but not required, to maintain a supply of potassium iodide. (nowtheendbegins.com)
Doses7
- Usually side effects of potassium iodide happen when people take higher doses for a long time. (directive21.com)
- Why Did Obama Give The Order For 14 Million Doses of Potassium Iodide? (nowtheendbegins.com)
- The Department of Health and Human Services has ordered 14 million doses of potassium iodide, the compound that protects the body from radioactive poisoning in the aftermath of severe nuclear accidents, to be delivered before the beginning of February. (nowtheendbegins.com)
- 14 million doses of Potassium Iodide say that might just be the case. (nowtheendbegins.com)
- Potassium iodate prophylaxis is not usually indicated in adults over 40 years unless doses to the thyroid from inhalation rise to levels threatening thyroid function, that is of the order of about 5 Gy. (medscape.co.uk)
- Pregnant women should receive no more than two doses of potassium iodide. (medscape.co.uk)
- However in the event of a nuclear accident, the use of potassium iodide in low doses over a short period of time, as a thyroid blocking agent is not contraindicated. (medscape.co.uk)
Iosat4
- Iosat™ Potassium Iodide by Anbex, Inc. (anbex.com)
- 8 packs of Iosat™ Potassium Iodide to protect your family. (anbex.com)
- Iosat Potassium Iodide has been FDA approved since 1982. (directive21.com)
- Indications- Iosat Potassium Iodide (KI) is a thyroid blocking medicine that is used in a nuclear radiation emergency only. (firstaidmart.com)
Take potassium7
- At this time, CDC does not recommend that people in the United States take Potassium Iodide (KI) or iodine supplements in response to the nuclear power plant explosions in Japan. (cdc.gov)
- People should take potassium iodide only on the advice of public health or emergency management officials. (readymaderesources.com)
- If you take potassium iodide, it will fill up your thyroid gland. (directive21.com)
- The only people who should not take potassium iodide are people who know they are allergic to iodide. (directive21.com)
- You may take potassium iodide even if you are taking medicines for a thyroid problem (for example, a thyroid hormone or antithyroid drug). (directive21.com)
- Take Potassium Iodide every day (every 24 hours) as directed. (firstaidmart.com)
- Have you been diagnosed with thyroid problems and need to take potassium iodide? (bono.shop)
Supplements3
- Do not use dietary supplements that contain iodine in the place of potassium iodide. (readymaderesources.com)
- Unlike other popular iodide supplements it is very uncommon to see undesirable coral tissue darkening when using this product. (bulkreefsupply.com)
- The Vitamin Shoppe offers a wide selection of potassium iodide supplements that are suitable for all types of diets. (wqidian.com)
Radioactive iodide1
- Since they may be ultimately metabolized or break down to radioactive iodide, it is common to administer non-radioactive potassium iodide to ensure that iodide from these radiopharmaceuticals is not sequestered by the normal affinity of the thyroid for iodide. (wikipedia.org)
Sodium5
- Dextrose or sodium thiosulfate are often added to iodized table salt to stabilize potassium iodide thus reducing loss of the volatile chemical. (wikipedia.org)
- potassium iodide will decrease the level or effect of sodium iodide I-131 by Other (see comment). (medscape.com)
- thyroid agents decrease uptake of sodium iodide I-131 by the thyroid gland. (medscape.com)
- PRODUCTS Methyl Iodide Sodium Iodide Potassium Iodate Iodine Potassium Iodide Download Brochure Enquiry Us Contact us for help? (bjcpl.in)
- Sodium iodide may be intravenously administered if oral intake is compromised. (medscape.com)
Tablet6
- Each Potassium Iodide tablet from Nature's Plus supplies 150 mcg of Iodine, the recommended daily value for adults. (arnoldsupplements.com)
- Each white, round, cross-scored tablet contains 130 mg potassium iodide. (firstaidmart.com)
- Iodoral - a tablet form of Lugol's solution (potassium iodide and iodine) - is not currently licensed for sale in Canada. (avivahealth.com)
- 65 mg potassium iodide (1 tablet) once daily. (medscape.co.uk)
- 32 mg potassium iodide (half a tablet) once daily. (medscape.co.uk)
- 16 mg potassium iodide (quarter of a tablet) once daily. (medscape.co.uk)
Hypothyroidism2
- Potassium iodide can help to protect the body against a variety of illnesses, such as goiter and hypothyroidism. (wqidian.com)
- Teratogenic effects such as congenital goitre and hypothyroidism have been reported when iodides, are administered to pregnant women. (medscape.co.uk)
Dose4
- A single dose of potassium iodide protects the thyroid gland for 24 hours. (readymaderesources.com)
- Suggested starting dose of Potassium iodide / fluoride concentrate: is 1 drop per 25 gallons but the dose should be adjusted to your tanks needs. (bulkreefsupply.com)
- This super dose of iodine from natural potassium iodide ensures your body gets the essential nutrients it needs. (ambrosialnutrifood.com)
- This mode of action dictates the use of an internal dose measure in the risk assessment that is indicative of fetal iodide status, such as cumulative iodide concentration (area-under-the-curve or AUC) for iodide in fetal blood. (cdc.gov)
Ingredients1
- While not containing exactly the same balance of ingredients, Alterra's Iomed potassium iodide and iodine formula is a licensed product in Canada, with Health Canada Natural Product Number: 80021356. (avivahealth.com)
Hyperthyroidism2
- Potassium iodide is also used along with antithyroid medicines to prepare the thyroidgland for surgical removal, to treat certain overactive thyroid conditions (hyperthyroidism), and to protect the thyroid in a radiation exposure emergency. (nutrawiki.org)
- Saturated solutions of potassium iodide can be an emergency treatment for hyperthyroidism (so-called thyroid storm), as high amounts of iodide temporarily suppress secretion of thyroxine from the thyroid gland. (nutrawiki.org)
Uptake2
- Thyroid iodine uptake blockade with potassium iodide is used in nuclear medicine scintigraphy and therapy with some radioiodinated compounds that are not targeted to the thyroid, such as iobenguane (MIBG), which is used to image or treat neural tissue tumors, or iodinated fibrinogen, which is used in fibrinogen scans to investigate clotting. (wikipedia.org)
- By saturating the body with a source of stable iodide prior to exposure, inhaled or ingested 131 I tends to be excreted, which prevents radioiodine uptake by the thyroid. (wikipedia.org)
Iodate1
- Potassium iodate (KIO3) is used to iodize some salts so that the iodine is not lost by oxidation. (wikipedia.org)
Optimal thyroid health2
- Potassium iodide is an essential component of several hormones that play an important role in maintaining optimal thyroid health. (wqidian.com)
- Ambrosial Iodine 5000mcg with Potassium Iodide 2500mcg, a potent formula for optimal thyroid health. (ambrosialnutrifood.com)
Good iodine1
- By taking Potassium Iodide (KI), the thyroid becomes saturated with "good iodine," leaving no room for the absorption of the "bad iodine" I-131. (peteprepstore.com)
Antithyroid1
- Drugs used in the treatment of Graves disease include thiourea antithyroid medications, iodide or iodine preparations, beta-blocking agents, and thyroid hormone. (medscape.com)
Suitable2
- Potassium Iodide is also suitable for use with animals and pets. (peteprepstore.com)
- Potassium iodide is most suitable for inhaled radioactive iodine and should not be used as the main prophylactic treatment against ingested iodine contamination. (medscape.co.uk)
Saturated Solution2
- For simple cutaneous forms, a saturated solution of potassium iodide is often used and is the least expensive form of treatment. (medscape.com)
- For simple cutaneous lesions, the least expensive medication for treatment is a saturated solution of potassium iodide. (medscape.com)
Fluoride2
- Potassium Iodide Fluoride (Kaliumjodid-Fluor Konzentrat) is designed to enhance the blue pigment in SPS corals. (bulkreefsupply.com)
- The effect of the combined use of silver diamine fluoride and potassium iodide in disrupting the plaque biofilm microbiome and alleviating tooth discoloration: A systematic review. (bvsalud.org)
Inorganic2
- Contains: Inorganic and organic iodide, bromine, potassium and fluorine. (bulkreefsupply.com)
- Potassium iodide is an inorganic compound with the chemical formula KI. (nutrawiki.org)
Concentration2
- Potassium Iodide is a mineral with a high concentration of iodine, and is an essential nutrient that can be readily added to your diet. (wqidian.com)
- APHA Method 4500-CLO2-B, iodometric titration analysis, measures the concentration of chlorine dioxide in water by titration with iodide, which is reduced to form iodine. (cdc.gov)
Taken up by the thyroid gland2
- Potassium iodide can help keep radioactive iodine from being taken up by the thyroid gland, which normally stores the element, according to scientists. (mv-voice.com)
- Iodide is a form of iodine that is preferentially taken up by the thyroid gland. (ayurvedicherbsdirect.com)
Thyroxine2
- Potassium iodide helps the body metabolize other hormones, such as thyroxine and triiodothyronine, which help regulate body temperature and metabolism. (wqidian.com)
- Alterra's combined potassium iodide and iodine supplement provides additional iodine to assist in normal bodily functions and encourage the thyroid gland to produce adequate levels of the thyroxine (T4) and triiodothyronine (T3) hormones. (avivahealth.com)
Oxidation2
- The oxidation of iodide causes slow loss of iodine content from iodised salts that are exposed to excess air. (wikipedia.org)
- These agents decrease iodide transport, iodide oxidation, and organification and suppress thyroid hormone release from the thyroid. (medscape.com)
Contain iodine1
- These compounds contain iodine, but not in the iodide form. (wikipedia.org)
Consult your physician1
- WARNING: Prior to taking Potassium Iodide, consult your physician if you have iodine allergies, dermatitis herpetiformis (DH), vasculitis, thyroid disease, or heart disease. (peteprepstore.com)
Supplement provides1
- Our Ambrosial Iodine with Potassium Iodide supplement provides essential support for maintaining a healthy thyroid. (ambrosialnutrifood.com)
Nutritional-supplement2
- Potassium-iodide is a nutritional-supplement in animal feeds and also in the human diet. (wikipedia.org)
- Alterra Io-Med is a potassium iodide nutritional supplement, not a radiation blocker. (avivahealth.com)
Medication2
- Potassium iodide is a chemical compound, medication, and dietary supplement. (wikipedia.org)
- Potassium iodide is available as a generic medication and over the counter. (wikipedia.org)
Thyroid hormones1
- The available data best support the hypothesis that the fetal effects were likely associated with modulation of the thyroid hormones by iodide during development. (cdc.gov)
Nuclear accident1
- Potassium Iodide helps protect your thyroid gland from radioactive iodine, in case of a nuclear accident. (life-enthusiast.com)
Essential mineral3
- Potassium iodide is an essential mineral that is quickly becoming a must-have for anyone looking to increase their vitamin and mineral intake. (wqidian.com)
- You can also find potassium iodide in multivitamins, which are easy to take and can help ensure you get enough of this essential mineral. (wqidian.com)
- In addition to iodine, NOW Foods Potassium Iodide also consists of potassium, an essential mineral for maintaining a healthy water and electrolyte balance and a balanced pH level throughout the body. (bono.shop)
Exposure5
- The alkali metal iodide salt, over time and exposure to excess oxygen and carbon dioxide, slowly oxidizes to metal carbonate and elemental iodine, which then evaporates. (wikipedia.org)
- By taking FDA approved potassium iodide prior to exposure of radioactive iodine, your thyroid will become saturated with safe, stable iodine. (directive21.com)
- In cases of exposure to radioactive iodine from nuclear accidents, dosing of potassium iodide should be based on emergency plans and predetermined operational intervention levels. (medscape.co.uk)
- Neonates in the first days of life are at particular risk of exposure to radio iodine and blocking of thyroid function by overload of potassium iodide. (medscape.co.uk)
- Measures to reduce radiation exposure in the immediate aftermath of a radiologic or nuclear disaster are described, including the diagnosis and management of external and internal contamination, use of potassium iodide, and actions in relation to breastfeeding. (cdc.gov)
Absorb1
- What potassium iodide does is to essentially fill up the thyroid glands with all the iodine they can absorb so that they cannot absorb any more. (urbansurvivalsite.com)
20011
- The Food and Drug Administration (FDA) released guidance in December 2001 on how to safely use potassium iodide. (readymaderesources.com)
Preparedness1
- Why Choose Potassium Iodide for Your Preparedness? (peteprepstore.com)
Radiation emergency1
- In a radiation emergency, potassium iodide blocks only the thyroid from absorbing radioactive iodine, protecting it from damage and reducing the risk of thyroid cancer. (nutrawiki.org)
Chemical2
- Potassium iodide has the chemical formula KI. (wikipedia.org)
- Potassium iodide is a chemical compound formed from potassium and iodine. (indianproductnews.com)
Pills2
- The Minister of Health, Alexandru Rafila, on Monday stated, in Ploiesti, that a campaign to distribute will start next week to distribute potassium iodide pills to the eligible population. (nineoclock.ro)
- EMERGENCY USE: The body does not produce Iodine naturally, which makes Potassium Iodide Pills perfect for emergency or survival kits. (readymaderesources.com)
Form1
- Potassium Iodide in the form contained in this product should only be taken as directed by healthcare practitioner. (balancedyouemporium.com)
Dietary2
- From dietary supplement to a protective medicine - potassium iodine has many uses. (indianproductnews.com)
- Potassium Iodide has been around for centuries as a dietary supplement, its power to help support your body is undeniable. (wqidian.com)
Stable4
- Potassium iodide (also called KI) is a salt of stable (not radioactive) iodine. (cdc.gov)
- Potasium iodide is a salt of stable (not radioactive) iodine that can help block radioiodine from being absorbed by the thyroid gland. (readymaderesources.com)
- IODINE FOR PROTECTION - Potassium Iodide (KI) is a stable iodine salt. (readymaderesources.com)
- Potassium iodide is a salt of stable iodine absorbed by the thyroid gland. (nutrigeek.shop)
Protect3
- In 1982, the U.S. Food and Drug Administration approved potassium iodide to protect thyroid glands from radioactive iodine involving accidents or fission emergencies. (wikipedia.org)
- Potassium iodide, or KI, can help protect the thyroid gland against harmful radioactive iodine when taken as directed during radiological emergencies. (westmayfieldborough.us)
- Potassium iodide is your go-to superpower to help protect your thyroid from radiation. (wqidian.com)
Salts1
- Potassium salts may increase the hyperkalemic effects of potassium-sparing diuretics. (medscape.com)
Promotes1
- Potassium Iodide promotes the synthesis of glutathione. (shreejipharmainternational.com)
Diseases1
- The powerful combination of iodine and potassium iodide in our supplement boosts renal function, reducing the risk of kidney diseases and promoting kidney health. (ambrosialnutrifood.com)