*  Asthma caused by aliphatic amines and polycyclic compounds - Phadia - Setting the Standard - Phadia.com - test

Asthma caused by aliphatic amines and polycyclic compounds. Chapter. Agents. Documents. Occupations. ...

*  Polycyclic aromatic compounds of environmental and occupational importance | SpringerLink

Polycyclic aromatic compounds of environmental and occupational importance. Their occurrence, toxicity and the development of ... Karcher W, Fordham R, Dubois J, Glaude Ph (1985) Spectral atlas of polycyclic aromatic compounds including data on occurrence ... This paper describes the preparation and certification of a complementary set of 9 polycyclic aromatic compounds (PAC) for ... Guerin MR (1978) Energy sources of polycyclic aromatic hydrocarbons. In: Gelboin HV, Ts'o POP (eds) Polycyclic hydrocarbons and ...

*  Abstract: Estimates of Atmospheric Deposition of Polycyclic Aromatic Compounds at Local and Regional Scales in the Athabasca...

... a monitoring program was established in 2011 to measure polycyclic aromatic compounds (PACs), including 17 polycyclic aromatic ... 17.6 Estimates of Atmospheric Deposition of Polycyclic Aromatic Compounds at Local and Regional Scales in the Athabasca Oil ...

*  ISBN 9781248995785 synthesis of bowl shaped polycyclic aromatic compounds and homo bi dentate

ISBN 9781248995785 - synthesis of bowl shaped polycyclic aromatic compounds and homo bi dentate ... UPC 9781248995785 synthesis of bowl shaped polycyclic aromatic compounds and homo bi dentate ...

*  Polycyclic aromatic compounds : an international and interdisciplinary journal | 東京工業大学附属図書館 蔵書検索 (OPAC)

図書 Polycyclic aromatic compounds : the journal of International Sociery for Polycyclic Aromatic Compounds : 14th International ... 図書 Polycyclic aromatic compounds : the journal of International Society for Polycyclic Aromatic Compounds : 15th International ... Polycyclic aromatic compounds : an international and interdisciplinary journal. 資料種別:. 雑誌. 出版情報:. New York ; Tokyo : Gordon and ... 図書 Spectral atlas of polycyclic aromatic compounds : including data on occurrence and biological activity ...

*  RCSB PDB - Ligand Summary Page

KEGG COMPOUND Searches KEGG COMPOUND for chemical substances and reactions that are relevant to life. ... A macrolide compound obtained from Streptomyces hygroscopicus that acts by selectively blocking the transcriptional activation ... A freely accessible resource for structural biologists who are dealing dealing with hetero-compounds ("small molecules") ...

*  Recerca

Design of new organocascade reactions to access biologically interesting compounds. * Delgado Cirilo, Antonio. Research unit on ...

*  Applications filed at Jul 14 2016 | ORGANIC LIGHT-EMITTING ELEMENT | Patents.com


*  Patent US5185260 - Method for distinguishing normal and transformed cells using G1 kinase ... - Google Patents

Polycyclic compounds and processes for the preparation thereof. US5475110 *. 14 Oct 1994. 12 Dec 1995. Cephalon, Inc.. Fused ... Polycyclic compounds and processes for the preparation thereof. US5455241 *. 20 Sep 1994. 3 Oct 1995. Ciba-Geigy Corporation. ...

*  Patent US4713055 - Artificially vascularized graft - Google Patents

Perfluoro polycyclic compounds for use as synthetic blood and perfusion media. US4160454 *. Feb 14, 1977. Jul 10, 1979. ... Riess J. Perfluoro Compounds as Blood Substitutes, Angew Chem Int Ed Engl 17:621, 1978. ... 5. Riess J. Perfluoro compounds as blood substitutes. Angew Chem Int Ed Engl 17:621, 1978. ...

*  Patente US20020143188 - Nitrosated and nitrosylated potassium channel activators, compositions and ... - Google Patentes

... and at least one compound that donates, transfers or releases nitric oxide, elevates endogenous levels of endothelium-derived ... at least one compound that donates, transfers or releases nitric oxide, elevates endogenous levels of endothelium-derived ... "Heterocyclic compounds" refer to mono- and polycyclic compounds comprising at least one aryl or heterocyclic ring. ... an O2N-O-heterocyclic compound, an O2N-N-heterocyclic compound, an O2N-S-heterocyclic compound or an O2N-C-heterocyclic ...

*  Dendralene - Wikipedia

... catalyzed Alder-ene/Diels-Alder/Diels-Alder reaction sequence affording rapid entry to polycyclic compounds". Tetrahedron. 61 ( ... A bicyclic [4]dendralene compound has been reported. [25]. References[edit]. *^ Henning Hopf, Classics in Hydrocarbon Chemistry ... One synthetic route to [4]dendralene starts from chloroprene.[11] This compound is converted to a Grignard reagent by action of ... This compound reacts with two equivalents of maleic anhydride in a tandem DA reaction:[6] ...

*  Aromatic compound synthesis > By alkyl or aryl transfer between molecules, e.g., disproportionation, etc. > Product is...

Product is polycyclic, of increased side-chain length, or a specific position polyalkyl benzene isomer > Using al or b halide ... Name: Chemistry of hydrocarbon compounds > Aromatic compound synthesis > By alkyl or aryl transfer between molecules, e.g., ... Process for production of bicyclic compounds. Oct. 31, 1978. 4026959. Low temperature isomerization process for ... Removing boron trifluoride from coordination compound contaminants in organic liquids. Feb. 21, 1984. ...

*  NIOSHTIC-2 Publications Search - 20039688 - Pilot study for the investigation of personal breathing zone and dermal exposure...

... asphalt paving workers to investigate the relative contribution of personal breathing zone and dermal exposures to polycyclic ... aromatic compounds, a two-part pilot (Phase I) was performed. The pilot study was important to examine the sources of exposure ... Pilot study for the investigation of personal breathing zone and dermal exposure using levels of polycyclic aromatic compounds ... to investigate the relative contribution of personal breathing zone and dermal exposures to polycyclic aromatic compounds, a ...

*  International Union of Pure and Applied Chemistry

Extension and revision of the von Baeyer system for naming polycyclic compounds (III.1) ... Nomenclature of organometallic compounds of the transition elements (II.2). *Definitions of terms for diffusion in the solid ... Revised Section F of the 1979 Blue Book: Natural products and related compounds (III.1) ... Extension and revision of the nomenclature for spiro compounds (III.1). * ...

*  Ketotifen - DrugBank

This compound belongs to the class of chemical entities known as cycloheptathiophenes. These are polycyclic compounds ... Aryl alkyl ketones / Piperidines / Benzenoids / Thiophenes / Heteroaromatic compounds / Trialkylamines / Azacyclic compounds / ... Cycloheptathiophene / Aryl alkyl ketone / Aryl ketone / Piperidine / Benzenoid / Thiophene / Heteroaromatic compound / Ketone ... Organopnictogen compounds / Organic oxides / Hydrocarbon derivatives Substituents. ...

*  Efectos tóxicos del alquilbencensulfonato lineal, antraceno y su mezcla sobre el crecimiento de un consorcio microbiano aislado...

Cerniglia E.C. and Heitkamp M.A. (1989). Microbial degradation of polycyclic compounds in the aquatic environment. In: ... Salmonella microsuspension assay as a tool to monitor for genotoxic polycyclic compounds in Santos estuary. Mutat. Res. 609, 60 ... 4 and 16 mg/L of each compound as described above. With 16 mg/L of each compound, a reduction in the growth of the consortium ... The objective was to evaluate the acute toxic effect of LAS, anthracene and the mixture of the two compounds on the growth of a ...

*  Compositions > Patents - Class:...

Halogenated polycyclic compound-containing. 33. 252/572. Metal- or insoluble component-containing; e.g., slurry, grease, etc.. ... Organic compounds of nonmetals other than c, h, and o. 430. 252/77. Organic compounds of nonmetals other than c, h, and o. 364 ... The organic compound contains silicon. 75. 252/519.32. The organic compound is a natural resin, protein, lignin, carbohydrate, ... The organic compound is a polymer. 366. 252/519.34. The metal compound contains halogen, sulfur, selenium, phosphorus, arsenic ...

*  313-72-4 - Octafluoronaphthalene, 96% - Perfluoronaphthalene - B21699 - Alfa Aesar

Polycyclic fluoroaromatic compounds. Part XII.[1] The extent of 1-substitution in octafluoronaphthalene.J. Fluor. Chem.,198527( ...

*  Sfoglia Scienze farmaceutiche per Titolo

Design and synthesis of new polycyclic compounds with potential anticancer activity  Musella, Simona (Universita degli studi ... The design and synthesis of novel N-heterocyclic compounds, and their evaluation of anti-cancer and anti-viral activity  More ... Design, synthesis and biological studies of novel heterocyclic compounds as anticancer drugs  Botta, Antonio (Universita degli ... The thesis entitled "The design and synthesis of novel N-heterocyclic compounds, and their evaluation of anti-cancer and anti- ...

*  Bøger af A. Leeson - find billigste pris på bogpriser.dk

Bioremediation of Chlorinated and Polycyclic Aromatic Hydrocarbon Compounds. af Battelle Memorial Institute; Robert E. Hinchee ...

*  KAKEN - Research Projects | Pational Control of Dimensional Structures of Metal-Assembled Ccmplexes (KAKENHI-PROJECT-10149104)

Publications] I.Ino,L.P.We,M.Munakata et al.: 'Silver(1) Complexes of Bridged Polycyclic Aromatic Compounds of ... Publications] M.Munakata: 'Supramolecular Silver(I)Complexes with Highly Strained Polycyclic Aromatic Compounds.' J.Am.Chem.Soc ... Publications] M.Yamashita: 'Charge Fluctuation in MMX Chain Compounds,R_4[Pt_2(pop)_4I].nH_2O' J.Am.Chem.Soc.(in press). (1999) ... Publications] S.Kuroda: 'ESR studies of halogen-bridged mixed-metal compounds Ni_,1-x,Pd_x(chxn)_2Br_3' Synth.Met.(in press). ( ...

*  Journal Rankings on Organic Chemistry

Polycyclic Aromatic Compounds journal. 0.402 Q3. 28. 123. 101. 2060. 128. 100. 1.42. 16.75. ... Spectroscopic Properties of Inorganic and Organometallic Compounds book serie. 0.158 Q4. 5. 9. 18. 1268. 8. 16. 0.60. 140.89. ...

*  Ingredient Glossary - PEG | Lavera Organic Makeup & Natural Skincare Store

... impurities found in various PEG compounds include ethylene oxide; 1,4-dioxane; polycyclic aromatic compounds; and heavy metals ... Despite this, the CIR concludes that many PEG compounds "are safe for use" in cosmetics but adds that PEG compounds should "not ... PEG compounds have been found to open the pores of the skin, enabling environmental toxins to more easily enter the body. ... of common toiletries contain PEG compounds and other impurities that are linked to breast cancer:. Mousse 90.3% Hair Dye 79.5% ...

*  A TIME'S MEMORY: Highly pathogenic #avian #influenza #H5N8, #Germany [thirty-one #poultry and #wildbirds #outbreaks] (#OIE, Feb...


(1/632) HPLC/fluorescence determination of anti-BPDE-DNA adducts in mononuclear white blood cells from PAH-exposed humans.

The aim of this study was to compare (+/-)-r-7,t-8-dihydroxy-t-9,10-oxy-7,8,9,10-tetrahydrobenzo[a]pyrene (anti-BPDE)-DNA adduct levels in groups of humans subjected to various levels of polycyclic aromatic hydrocarbon (PAH) (benzo[a]pyrene) exposure. An HPLC/fluorescence method was applied to detect specifically anti-BPDE-DNA adducts in mononuclear white blood cells [lymphocyte plus monocyte fraction (LMF)] from humans exposed to PAHs. A total of 130 subjects comprised the sample population: 26 psoriatic patients (3 days after clinical coal tar treatment of the skin), 15 coke oven workers, 19 chimney sweeps, 36 aluminium anode plant workers and 34 non-occupationally PAH-exposed subjects (controls). PAH exposure was assessed in each group by means of the urinary excretion of 1-pyrenol (mean group levels: 1.2, 0.7, 0.3, 65.0 and 0.1 micromol/mol creatinine in coke oven workers, chimney sweeps, aluminium plant anode workers, psoriatic patients and non-occupationally PAH-exposed subjects, respectively). HPLC/fluorescence analysis of BPDE-DNA adducts showed that the percentage of subjects with adduct levels exceeding the 95 percentile control subject value (8.9 adducts/10(8) nucleotides) was significantly high in coke oven workers (46.7%) and chimney sweeps (21.0%) (chi2 test, P < 0.01 and P < 0.05, respectively) but not in aluminium plant workers (11.1%) and psoriatic patients (0%). The increase in BPDE-DNA adduct levels in LMF (Ln values) was significantly related to chronic inhalatory and high PAH exposure (linear multiple regression analysis, F = 6.37, P < 0.01; t = 4.2, P < 0.001). Skin acute (or short-term) and high PAH exposure, charcoal-grilled meat consumption and smoking habit did not seem to influence BPDE-DNA adduct formation in LMF.  (+info)

(2/632) Structure-activity relationship of schisandrins in enhancing liver mitochondrial glutathione status in CCl4-poisoned mice.

AIM: To explore whether the methylenedioxy group and cyclooctadiene ring of the dibenzocyclooctadiene skeleton of schisandrins (Sch) play a role in the liver mitochondrial glutathione status enhancing activity. METHOD: The effects of three dibenzocyclooctadiene derivatives, Sch A, Sch B, Sch C, and a synthetic intermediate of Sch C, (dimethyl biphenyl dicarboxylate, DBD) on carbon tetrachloride (CCl4)-hepatotoxicity and liver mitochondrial glutathione status were examined in mice. RESULTS: Pretreating mice with intragastric Sch B, Sch C, or DBD 1.mmol.kg-1.d-1 for 3 d protected against CCl4-hepatotoxicity. The hepatoprotection afforded by Sch B or Sch C pretreatment was associated with increases in liver mitochondrial reduced glutathione (mtGSH) level and glutathione reductase (mtGRD) activity, an indication of enhanced mitochondrial glutathione status. In contrast, the hepatoprotective action of DBD was not accompanied by any detectable changes in mtGSH level and mtGRD activity. CONCLUSION: Both the methylenedioxy group and the cyclooctadiene ring of the dibenzocyclooctadiene molecule are important structural determinants in the enhancement of liver mitochondrial glutathione status.  (+info)

(3/632) Dose-dependent preferential binding of polycyclic aromatic hydrocarbons to reiterated DNA of murine skin cells in culture.

The distribution of active metabolites of polycyclic aromatic hydrocarbons bound to reiterated or unique regions of murine DNA has been studied by a DNA-DNA renaturation technique. Murine skin cells were exposed to different doses of radioactive polycyclic aromatic hydrocarbons for 24 hr; then the hydrocarbon-labeled DNA was isolated, fragmented, and denatured. Renaturation kinetics and thermal stabilities of DNA-DNA duplexes were studied. At high carcinogen doses, polycyclic aromatic hydrocarbon adducts seem to be distributed equally among the DNA of all reiteration frequencies. At low carcinogen doses, however, a dose-dependent preferential binding to reiterated DNA sequences occurs. An inverse linear relationship appears to exist between the enrichment of hydrocarbon adducts in reiterated DNA sequences and the logarithm of the amount of total hydrocarbon bound to DNA.  (+info)

(4/632) Cancer initiation by polycyclic aromatic hydrocarbons results from formation of stable DNA adducts rather than apurinic sites.

Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental pollutants with high carcinogenic potencies that have been linked to the etiology of human cancers through their presence in cigarette smoke and environmental mixtures. They are metabolically activated in cells by cytochrome P450 enzymes and/or peroxidases to reactive intermediates that damage DNA. One pathway of activation forms dihydrodiol epoxides that covalently bind to exocyclic amino groups of purines in DNA to form stable adducts. Another pathway involves formation of radical cations that bind to the N7 or C8 of purines to form unstable adducts that depurinate to leave apurinic (AP) sites in DNA. In the present study the proportions of stable DNA adducts and AP sites formed by the carcinogenic PAHs dibenzo[a,l]-pyrene (DB[a,l]P), 7,12-dimethylbenz[a]anthracene (DMBA), and benzo[a]pyrene (B[a]P) have been investigated in a target tissue for carcinogenesis, mouse epidermis. After topical application of the PAHs on the skin of female SENCAR mice epidermal DNA was isolated and the formation of stable DNA adducts was measured by (33)P-postlabeling and HPLC analysis. AP sites in DNA were measured with an aldehyde reactive probe in a slot-blot assay. At both 4 and 24 h after exposure, DB[a,l]P formed significantly higher amounts of stable DNA adducts than DMBA, and B[a]P exhibited the lowest level of binding. In contrast, the number of AP sites present in mice treated with these PAHs was in the order: DMBA > B[a]P >> DB[a,l]P. The level of AP sites was significantly lower than the level of stable adducts for each PAH. The most potent carcinogen, DB[a,l]P, induced the highest level of stable adducts and the lowest level of AP sites in epidermal DNA. These results indicate that stable DNA adducts rather than AP sites are responsible for tumor initiation by carcinogenic PAHs.  (+info)

(5/632) Environmental pollution and human exposure to polycyclic aromatic hydrocarbons in the east Baltic region.

Environmental contamination by polycyclic aromatic hydrocarbons (PAH) and human exposure were surveyed in the east Baltic region. Polluted and heavily industrialized areas are upper Silesia in Poland, northern Bohemia in the Czech Republic, and the northeast part of Estonia. In Estonia the pollution is in a defined geographic area, where lung cancer incidence is higher than elsewhere. In Silesia, exposure of some 5 million people appears to be elevated; DNA (deoxyribonucleic acid) adduct levels in white blood cells are increased in groups of residents with apparently only environmental exposure. By extrapolation, some 150 annual lung cancer cases could be predicted due to PAH in Silesia. Air levels of benzo[a]pyrene were increased in northern Bohemia, and domestic heating and power plants using brown coal appeared to be major contributors to particulate air pollution in winter. Further studies are needed to assess health risks of PAH exposure in central and eastern Europe.  (+info)

(6/632) Alternative pathways of polycyclic aromatic hydrocarbons activation: the formation of polar DNA adducts.

Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental pollutants, and some are potent carcinogens in rodents. Carcinogenic PAHs are activated in the cells to metabolites that react with DNA to form covalent adducts. For most PAHs the reactive, electrophilic species which bind to DNA, are bay-region diol-epoxides. Application of 32P-postlabeling to PAH-DNA adducts analysis revealed that for some PAHs the adduct profiles generated in model systems are more complex and include adducts which are more polar than those formed by classic bay-region diol-epoxides. This minireview summaries the information gained on typical representatives of polar PAH-DNA adducts. Formation of triol-epoxide-DNA adducts was proposed for chrysene and a non-alterant PAH, benzo[b]fluoranthene (B[b]F). 5-OH-B[b]F, the precursor of B[b]F triol-epoxide, was found to be a potent tumor initiator in mouse skin. For planar PAHs such as dibenzanthracenes the possibility of bis-diol epoxide-DNA adducts formation was suggested. The most comprehensive data were obtained for dibenz[a,j]anthracene (DB[a,j]A). This hydrocarbon when applied to SENCAR mouse skin forms up to 23 species of adducts, most of which are polar. Among these polar adducts seven were identified as derived from DB[aj]A-3,4-10,11-bis-diol. Analysis of tumor-initiating activity showed, however, that this proximate metabolite was inactive in this respect. In contrast, an excellent correlation was observed between levels of less polar DNA adducts (i.e. those derived from bay-region diolepoxides) and skin tumor initiating activity of DB[a,j]A. Thus, while triol-epoxides seems to be involved in tumor initiating activity of the parent compound, non alterant B[b]F, the significance of bis-diol epoxide-DNA adducts, at least those derived from DB[aj]A, is minor.  (+info)

(7/632) Mutability of different genetic loci in mammalian cells by metabolically activated carcinogenic polycyclic hydrocarbons.

The relationship between carcinogenesis and mutagenesis in mammalian cells has been determined with 10 polycyclic hydrocarbons with different degrees of carcinogenicity. Mutagenesis was determined in Chinese hamster cells with genetic markers that affect the surface membrane, nucleic-acid synthesis, and protein synthesis. The mutations were characterized by resistance to ouabain, 8-azaguanine, and temperature. Mutagenesis by the carcinogens required metabolic activation and this was provided by the presence of lethally irradiated metabolizing cells. The degree of carcinogenicity was related to the degree of mutagenicity for all three genetic markers. The most potent carcinogen, 7,12-dimethylbenz[a]anthracene, gave the highest mutagenicity and mutagenicity was obtained with 0.01 mug/ml. Treatment of the cells with aminophylline, which increases polycyclic hydrocarbon metabolism, increased mutagenesis by the carcinogens. It is suggested that such an experimental system with these and other mammalian cells should be useful as a sensitive assay for hazardous environmental chemicals.  (+info)

(8/632) Effect of plant matrix and fluid ethanol concentration on supercritical fluid extraction efficiency of schisandrin derivatives.

An investigation of the effect of plant matrix on the supercritical fluid extraction efficiency of five schisandrin derivatives is reported, exhibiting a great difference with respect to extraction efficiency depending on the matrix. Pure supercritical CO2 at 60 degrees C and 34.0 MPa cannot fully recover schisandrin derivatives from the leaves as much as from the other matrices. Only 36.9% of these compounds are extracted from leaves of Schisandra chinensis by supercritical CO2 in comparison with organic solvent extraction. However, more than 80% of schisandrin derivatives are obtained from both stem and fruit parts. Ethanol addition also shows a different effect depending on plant matrix; that is, CO2 modified with 10% ethanol could enhance the yield of schisandrin derivatives from leaves by four times when compared with that of pure CO2, but it has little effect on both stems and fruits.  (+info)

aromatic hydrocarbon

  • pdf) In a statement Monday issued at the request of the Hong Kong Stock Exchange, Samsonite said levels of polycyclic aromatic hydrocarbon , or PAH, found in the handles of three models of Tokyo Chic luggage, made under Samsonite's American Tourister brand, were lower than what was reported in an article published by the Hong Kong Consumer Council. (thefreedictionary.com)
  • Anthracene, phenanthrene, and pyrene are polycyclic aromatic hydrocarbon (PAHs) that display both mutagenic and carcinogenic properties. (redorbit.com)


  • Edible oils such as palm, corn and sunflower oils were analyzed for the presence of light and heavy polycyclic aromatic hydrocarbons (PAHs) using liquid-liquid extraction, clean-up on a silica gel column, and determination by High Performance Liquid Chromatography (HPLC) using a fluorescene detector. (ums.edu.my)
  • Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental contaminants formed from the incomplete combustion of fossil fuels and are found in the environment as complex mixtures. (duke.edu)
  • The purpose of this contract involves the collection and analysis for the detection of asbestos and polycyclic aromatic hydrocarbons (pahs) in asphalt pavement on the entire road network in the indre-et loire. (thefreedictionary.com)
  • Polycyclic Aromatic Hydrocarbons ( PAHs) are generally considered carcinogenic & mutagenic, and are hence considered an important air pollutant that needs to be monitored Lung cancer is the most serious health risk from exposure to PAHs. (thefreedictionary.com)
  • Results of a study of the ban's impact were just published in a paper titled Polycyclic Aromatic Hydrocarbons (PAHs) in Austin Sediments After A Ban on Pavement Sealers in Environmental Forensics, the journal of the International Society of Environmental Forensics. (thefreedictionary.com)
  • Polycyclic aromatic hydrocarbons (PAHs) are a group of chemical compounds consisting of several atoms of carbon and hydrogen, arranged in the form of two or more aromatic rings. (redorbit.com)
  • Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental contaminants that can be modified to oxygenated PAH (oxyPAHs) derivatives. (uwaterloo.ca)
  • To assess ecosystem health and cumulative environmental effects associated with mining activities in the Athabasca oil sands region, western Canada, a monitoring program was established in 2011 to measure polycyclic aromatic compounds (PACs), including 17 polycyclic aromatic hydrocarbons (PAHs), 21 alkylated PAHs, and 5 parent and alkylated dibenzothiophenes (DBTs) at 17 passive and three active sampling sites. (confex.com)


  • 2001). Viability was decreased in CL cells exposed to PHEQ and 1,2-dihydroxy-anthraquinone (1,2-dhATQ), but not their parent compounds phenanthrene (PHE) or anthracene (ANT). (uwaterloo.ca)


  • Also presented are newly measured UV-absorption maxima, and a review of the occurrence and biological activities (bacterial mutagenicity tests and animal carcinogenic data) of the compounds in this latest series of PAC reference materials. (springer.com)


  • Simple mixtures consisting of a PAH that is an AHR agonist (benzo[a]pyrene or benzo[k]fluoranthene) and a PAH that is a cytochrome P450 1 (CYP1) inhibitor (fluoranthene) were used in these experiments along with the dioxin-like compound 3,3',4,4',5-pentachlorobiphenyl (PCB-126). (duke.edu)


  • This paper describes the preparation and certification of a complementary set of 9 polycyclic aromatic compounds (PAC) for calibration and reference purposes in environmental and occupational analysis, increasing the total number of BCR reference compounds of this class of ubiquitous pollutants to 48. (springer.com)


  • The polycyclic aromatic hydrocarbons tend to stick around a bit longer: they're more difficult for microbes to break down. (thefreedictionary.com)
  • It is well known that oxyPAHs tend to be much more reactive than their parent compounds. (uwaterloo.ca)


  • FDA also calculated allowable thresholds, known as levels of concern, for polycyclic aromatic hydrocarbons in each type of Gulf seafood it tested. (thefreedictionary.com)


  • Lymphocyte phenotype analysis and chromosome aberration frequency of workers occupationally exposed to styrene, benzene, polycyclic aromatic hydrocarbons , or mixed solvents. (thefreedictionary.com)
  • His current interests include the development and application of new and novel methods for sensitive, specific, fast, and accurate quantitative analysis for environmentally significant compounds in human tissues. (psu.edu)