A non-metal element that has the atomic symbol P, atomic number 15, and atomic weight 31. It is an essential element that takes part in a broad variety of biochemical reactions.
Stable phosphorus atoms that have the same atomic number as the element phosphorus, but differ in atomic weight. P-31 is a stable phosphorus isotope.
Atomic species differing in mass number but having the same atomic number. (Grant & Hackh's Chemical Dictionary, 5th ed)
Phosphorus used in foods or obtained from food. This element is a major intracellular component which plays an important role in many biochemical pathways relating to normal physiological functions. High concentrations of dietary phosphorus can cause nephrocalcinosis which is associated with impaired kidney function. Low concentrations of dietary phosphorus cause an increase in calcitriol in the blood and osteoporosis.
Techniques for labeling a substance with a stable or radioactive isotope. It is not used for articles involving labeled substances unless the methods of labeling are substantively discussed. Tracers that may be labeled include chemical substances, cells, or microorganisms.
Stable oxygen atoms that have the same atomic number as the element oxygen, but differ in atomic weight. O-17 and 18 are stable oxygen isotopes.
Stable nitrogen atoms that have the same atomic number as the element nitrogen, but differ in atomic weight. N-15 is a stable nitrogen isotope.
Stable carbon atoms that have the same atomic number as the element carbon, but differ in atomic weight. C-13 is a stable carbon isotope.
Inorganic compounds that contain phosphorus as an integral part of the molecule.
Stable zinc atoms that have the same atomic number as the element zinc, but differ in atomic weight. Zn-66-68, and 70 are stable zinc isotopes.
Inorganic salts of phosphoric acid.
Stable sulfur atoms that have the same atomic number as the element sulfur, but differ in atomic weight. S-33, 34, and 36 are stable sulfur isotopes.
Disorders in the processing of phosphorus in the body: its absorption, transport, storage, and utilization.
Deuterium. The stable isotope of hydrogen. It has one neutron and one proton in the nucleus.
Stable iron atoms that have the same atomic number as the element iron, but differ in atomic weight. Fe-54, 57, and 58 are stable iron isotopes.
An enzyme that catalyzes the conversion of myo-inositol hexakisphosphate and water to 1L-myo-inositol 1,2,3,4,5-pentakisphosphate and orthophosphate. EC 3.1.3.26.
Native, inorganic or fossilized organic substances having a definite chemical composition and formed by inorganic reactions. They may occur as individual crystals or may be disseminated in some other mineral or rock. (Grant & Hackh's Chemical Dictionary, 5th ed; McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
An element with the atomic symbol N, atomic number 7, and atomic weight [14.00643; 14.00728]. Nitrogen exists as a diatomic gas and makes up about 78% of the earth's atmosphere by volume. It is a constituent of proteins and nucleic acids and found in all living cells.
A polypeptide hormone (84 amino acid residues) secreted by the PARATHYROID GLANDS which performs the essential role of maintaining intracellular CALCIUM levels in the body. Parathyroid hormone increases intracellular calcium by promoting the release of CALCIUM from BONE, increases the intestinal absorption of calcium, increases the renal tubular reabsorption of calcium, and increases the renal excretion of phosphates.
A condition of abnormally high level of PHOSPHATES in the blood, usually significantly above the normal range of 0.84-1.58 mmol per liter of serum.
Calcium compounds used as food supplements or in food to supply the body with calcium. Dietary calcium is needed during growth for bone development and for maintenance of skeletal integrity later in life to prevent osteoporosis.
Stable strontium atoms that have the same atomic number as the element strontium, but differ in the atomic weight. Sr-84, 86, 87, and 88 are the stable strontium isotopes.
A basic element found in nearly all organized tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.
The unconsolidated mineral or organic matter on the surface of the earth that serves as a natural medium for the growth of land plants.
The enrichment of a terrestrial or aquatic ECOSYSTEM by the addition of nutrients, especially nitrogen and phosphorus, that results in a superabundant growth of plants, ALGAE, or other primary producers. It can be a natural process or result from human activity such as agriculture runoff or sewage pollution. In aquatic ecosystems, an increase in the algae population is termed an algal bloom.
Method for assessing flow through a system by injection of a known quantity of radionuclide into the system and monitoring its concentration over time at a specific point in the system. (From Dorland, 28th ed)
Complexing agent for removal of traces of heavy metal ions. It acts also as a hypocalcemic agent.
Spectroscopic method of measuring the magnetic moment of elementary particles such as atomic nuclei, protons or electrons. It is employed in clinical applications such as NMR Tomography (MAGNETIC RESONANCE IMAGING).
Regular course of eating and drinking adopted by a person or animal.
Substances or mixtures that are added to the soil to supply nutrients or to make available nutrients already present in the soil, in order to increase plant growth and productivity.
A nonmetallic element with atomic symbol C, atomic number 6, and atomic weight [12.0096; 12.0116]. It may occur as several different allotropes including DIAMOND; CHARCOAL; and GRAPHITE; and as SOOT from incompletely burned fuel.
Total mass of all the organisms of a given type and/or in a given area. (From Concise Dictionary of Biology, 1990) It includes the yield of vegetative mass produced from any given crop.
An analytical method used in determining the identity of a chemical based on its mass using mass analyzers/mass spectrometers.
A condition of an abnormally low level of PHOSPHATES in the blood.
A specialized CONNECTIVE TISSUE that is the main constituent of the SKELETON. The principle cellular component of bone is comprised of OSTEOBLASTS; OSTEOCYTES; and OSTEOCLASTS, while FIBRILLAR COLLAGENS and hydroxyapatite crystals form the BONE MATRIX.
Methods for assessing flow through a system by injection of a known quantity of an indicator, such as a dye, radionuclide, or chilled liquid, into the system and monitoring its concentration over time at a specific point in the system. (From Dorland, 28th ed)
The rate dynamics in chemical or physical systems.
A mass of organic or inorganic solid fragmented material, or the solid fragment itself, that comes from the weathering of rock and is carried by, suspended in, or dropped by air, water, or ice. It refers also to a mass that is accumulated by any other natural agent and that forms in layers on the earth's surface, such as sand, gravel, silt, mud, fill, or loess. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed, p1689)
The physical or physiological processes by which substances, tissue, cells, etc. take up or take in other substances or energy.
The usually underground portions of a plant that serve as support, store food, and through which water and mineral nutrients enter the plant. (From American Heritage Dictionary, 1982; Concise Dictionary of Biology, 1990)
The physiologically active form of vitamin D. It is formed primarily in the kidney by enzymatic hydroxylation of 25-hydroxycholecalciferol (CALCIFEDIOL). Its production is stimulated by low blood calcium levels and parathyroid hormone. Calcitriol increases intestinal absorption of calcium and phosphorus, and in concert with parathyroid hormone increases bone resorption.
A metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION.
Inorganic salts or organic esters of phosphorous acid that contain the (3-)PO3 radical. (From Grant & Hackh's Chemical Dictionary, 5th ed)
Foodstuff used especially for domestic and laboratory animals, or livestock.
A condition characterized by calcification of the renal tissue itself. It is usually seen in distal RENAL TUBULAR ACIDOSIS with calcium deposition in the DISTAL KIDNEY TUBULES and the surrounding interstitium. Nephrocalcinosis causes RENAL INSUFFICIENCY.
Abnormally elevated PARATHYROID HORMONE secretion as a response to HYPOCALCEMIA. It is caused by chronic KIDNEY FAILURE or other abnormalities in the controls of bone and mineral metabolism, leading to various BONE DISEASES, such as RENAL OSTEODYSTROPHY.
An enzyme that catalyzes the conversion of an orthophosphoric monoester and water to an alcohol and orthophosphate. EC 3.1.3.1.
Identification and measurement of ELEMENTS and their location based on the fact that X-RAYS emitted by an element excited by an electron beam have a wavelength characteristic of that element and an intensity related to its concentration. It is performed with an electron microscope fitted with an x-ray spectrometer, in scanning or transmission mode.
Linear polymers in which orthophosphate residues are linked with energy-rich phosphoanhydride bonds. They are found in plants, animals, and microorganisms.
Uptake of substances through the lining of the INTESTINES.
Refuse liquid or waste matter carried off by sewers.
Disorders caused by interruption of BONE MINERALIZATION manifesting as OSTEOMALACIA in adults and characteristic deformities in infancy and childhood due to disturbances in normal BONE FORMATION. The mineralization process may be interrupted by disruption of VITAMIN D; PHOSPHORUS; or CALCIUM homeostasis, resulting from dietary deficiencies, or acquired, or inherited metabolic, or hormonal disturbances.
A microanalytical technique combining mass spectrometry and gas chromatography for the qualitative as well as quantitative determinations of compounds.
Unstable isotopes of phosphorus that decay or disintegrate emitting radiation. P atoms with atomic weights 28-34 except 31 are radioactive phosphorus isotopes.
Substances which are of little or no nutritive value, but are used in the processing or storage of foods or animal feed, especially in the developed countries; includes ANTIOXIDANTS; FOOD PRESERVATIVES; FOOD COLORING AGENTS; FLAVORING AGENTS; ANTI-INFECTIVE AGENTS (both plain and LOCAL); VEHICLES; EXCIPIENTS and other similarly used substances. Many of the same substances are PHARMACEUTIC AIDS when added to pharmaceuticals rather than to foods.
Therapy for the insufficient cleansing of the BLOOD by the kidneys based on dialysis and including hemodialysis, PERITONEAL DIALYSIS, and HEMODIAFILTRATION.
The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.
The normality of a solution with respect to HYDROGEN ions; H+. It is related to acidity measurements in most cases by pH = log 1/2[1/(H+)], where (H+) is the hydrogen ion concentration in gram equivalents per liter of solution. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
Carbonic acid calcium salt (CaCO3). An odorless, tasteless powder or crystal that occurs in nature. It is used therapeutically as a phosphate buffer in hemodialysis patients and as a calcium supplement.
A functional system which includes the organisms of a natural community together with their environment. (McGraw Hill Dictionary of Scientific and Technical Terms, 4th ed)
Water containing no significant amounts of salts, such as water from RIVERS and LAKES.
Substances that comprise all matter. Each element is made up of atoms that are identical in number of electrons and protons and in nuclear charge, but may differ in mass or number of neutrons.
Stable mercury atoms that have the same atomic number as the element mercury, but differ in atomic weight. Hg-196, 198-201, and 204 are stable mercury isotopes.
Accumulations of solid or liquid animal excreta usually from stables and barnyards with or without litter material. Its chief application is as a fertilizer. (From Webster's 3d ed)
A family of gram-negative, moderately halophilic bacteria in the order Oceanospirillales. Members of the family have been isolated from temperate and Antarctic saline lakes, solar salt facilities, saline soils, and marine environments.
A metallic element that has the atomic number 13, atomic symbol Al, and atomic weight 26.98.
New immature growth of a plant including stem, leaves, tips of branches, and SEEDLINGS.
Excrement from the INTESTINES, containing unabsorbed solids, waste products, secretions, and BACTERIA of the DIGESTIVE SYSTEM.
Two pairs of small oval-shaped glands located in the front and the base of the NECK and adjacent to the two lobes of THYROID GLAND. They secrete PARATHYROID HORMONE that regulates the balance of CALCIUM; PHOSPHORUS; and MAGNESIUM in the body.
An endogenous substance found mainly in skeletal muscle of vertebrates. It has been tried in the treatment of cardiac disorders and has been added to cardioplegic solutions. (Reynolds JEF(Ed): Martindale: The Extra Pharmacopoeia (electronic version). Micromedex, Inc, Englewood, CO, 1996)
Conditions in which the KIDNEYS perform below the normal level for more than three months. Chronic kidney insufficiency is classified by five stages according to the decline in GLOMERULAR FILTRATION RATE and the degree of kidney damage (as measured by the level of PROTEINURIA). The most severe form is the end-stage renal disease (CHRONIC KIDNEY FAILURE). (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002)
Decalcification of bone or abnormal bone development due to chronic KIDNEY DISEASES, in which 1,25-DIHYDROXYVITAMIN D3 synthesis by the kidneys is impaired, leading to reduced negative feedback on PARATHYROID HORMONE. The resulting SECONDARY HYPERPARATHYROIDISM eventually leads to bone disorders.
The sequence of transfers of matter and energy from organism to organism in the form of FOOD. Food chains intertwine locally into a food web because most organisms consume more than one type of animal or plant. PLANTS, which convert SOLAR ENERGY to food by PHOTOSYNTHESIS, are the primary food source. In a predator chain, a plant-eating animal is eaten by a larger animal. In a parasite chain, a smaller organism consumes part of a larger host and may itself be parasitized by smaller organisms. In a saprophytic chain, microorganisms live on dead organic matter.
A vitamin that includes both CHOLECALCIFEROLS and ERGOCALCIFEROLS, which have the common effect of preventing or curing RICKETS in animals. It can also be viewed as a hormone since it can be formed in SKIN by action of ULTRAVIOLET RAYS upon the precursors, 7-dehydrocholesterol and ERGOSTEROL, and acts on VITAMIN D RECEPTORS to regulate CALCIUM in opposition to PARATHYROID HORMONE.
The first chemical element in the periodic table. It has the atomic symbol H, atomic number 1, and atomic weight [1.00784; 1.00811]. It exists, under normal conditions, as a colorless, odorless, tasteless, diatomic gas. Hydrogen ions are PROTONS. Besides the common H1 isotope, hydrogen exists as the stable isotope DEUTERIUM and the unstable, radioactive isotope TRITIUM.
Organic compounds that contain phosphorus as an integral part of the molecule. Included under this heading is broad array of synthetic compounds that are used as PESTICIDES and DRUGS.
Free-floating minute organisms that are photosynthetic. The term is non-taxonomic and refers to a lifestyle (energy utilization and motility), rather than a particular type of organism. Most, but not all, are unicellular algae. Important groups include DIATOMS; DINOFLAGELLATES; CYANOBACTERIA; CHLOROPHYTA; HAPTOPHYTA; CRYPTOMONADS; and silicoflagellates.
The discarding or destroying of liquid waste products or their transformation into something useful or innocuous.
An annual legume. The SEEDS of this plant are edible and used to produce a variety of SOY FOODS.
The region of the HAND between the WRIST and the FINGERS.
A plant genus of the family FABACEAE that is a source of SPARTEINE, lupanine and other lupin alkaloids.
The isotopic compound of hydrogen of mass 2 (deuterium) with oxygen. (From Grant & Hackh's Chemical Dictionary, 5th ed) It is used to study mechanisms and rates of chemical or nuclear reactions, as well as biological processes.
Creation and development of bodies within solar systems, includes study of early planetary geology.
Nutritional physiology of animals.
A metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn.
Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).
Symbiotic combination (dual organism) of the MYCELIUM of FUNGI with the roots of plants (PLANT ROOTS). The roots of almost all higher plants exhibit this mutually beneficial relationship, whereby the fungus supplies water and mineral salts to the plant, and the plant supplies CARBOHYDRATES to the fungus. There are two major types of mycorrhizae: ectomycorrhizae and endomycorrhizae.
Proteins obtained from foods. They are the main source of the ESSENTIAL AMINO ACIDS.
Hydroxy analogs of vitamin D 3; (CHOLECALCIFEROL); including CALCIFEDIOL; CALCITRIOL; and 24,25-DIHYDROXYVITAMIN D 3.
Inorganic compounds that contain calcium as an integral part of the molecule.
A rating of a body of water based on measurable physical, chemical, and biological characteristics.
Isotopes that exhibit radioactivity and undergo radioactive decay. (From Grant & Hackh's Chemical Dictionary, 5th ed & McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Derivatives of ERGOSTEROL formed by ULTRAVIOLET RAYS breaking of the C9-C10 bond. They differ from CHOLECALCIFEROL in having a double bond between C22 and C23 and a methyl group at C24.
Elements of limited time intervals, contributing to particular results or situations.
Expanded structures, usually green, of vascular plants, characteristically consisting of a bladelike expansion attached to a stem, and functioning as the principal organ of photosynthesis and transpiration. (American Heritage Dictionary, 2d ed)
An inherited condition of abnormally low serum levels of PHOSPHATES (below 1 mg/liter) which can occur in a number of genetic diseases with defective reabsorption of inorganic phosphorus by the PROXIMAL RENAL TUBULES. This leads to phosphaturia, HYPOPHOSPHATEMIA, and disturbances of cellular and organ functions such as those in X-LINKED HYPOPHOSPHATEMIC RICKETS; OSTEOMALACIA; and FANCONI SYNDROME.
The extent to which the active ingredient of a drug dosage form becomes available at the site of drug action or in a biological medium believed to reflect accessibility to a site of action.
Tools or devices for generating products using the synthetic or chemical conversion capacity of a biological system. They can be classical fermentors, cell culture perfusion systems, or enzyme bioreactors. For production of proteins or enzymes, recombinant microorganisms such as bacteria, mammalian cells, or insect or plant cells are usually chosen.
Chemical compounds which pollute the water of rivers, streams, lakes, the sea, reservoirs, or other bodies of water.
A great expanse of continuous bodies of salt water which together cover more than 70 percent of the earth's surface. Seas may be partially or entirely enclosed by land, and are smaller than the five oceans (Atlantic, Pacific, Indian, Arctic, and Antarctic).
Any of several processes in which undesirable impurities in water are removed or neutralized; for example, chlorination, filtration, primary treatment, ion exchange, and distillation. It includes treatment of WASTE WATER to provide potable and hygienic water in a controlled or closed environment as well as provision of public drinking water supplies.
Minute free-floating animal organisms which live in practically all natural waters.
A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Pathologic deposition of calcium salts in tissues.
An element that is a member of the chalcogen family. It has an atomic symbol S, atomic number 16, and atomic weight [32.059; 32.076]. It is found in the amino acids cysteine and methionine.
A family of small polypeptide growth factors that share several common features including a strong affinity for HEPARIN, and a central barrel-shaped core region of 140 amino acids that is highly homologous between family members. Although originally studied as proteins that stimulate the growth of fibroblasts this distinction is no longer a requirement for membership in the fibroblast growth factor family.
One of the three domains of life (the others being Eukarya and ARCHAEA), also called Eubacteria. They are unicellular prokaryotic microorganisms which generally possess rigid cell walls, multiply by cell division, and exhibit three principal forms: round or coccal, rodlike or bacillary, and spiral or spirochetal. Bacteria can be classified by their response to OXYGEN: aerobic, anaerobic, or facultatively anaerobic; by the mode by which they obtain their energy: chemotrophy (via chemical reaction) or PHOTOTROPHY (via light reaction); for chemotrophs by their source of chemical energy: CHEMOLITHOTROPHY (from inorganic compounds) or chemoorganotrophy (from organic compounds); and by their source for CARBON; NITROGEN; etc.; HETEROTROPHY (from organic sources) or AUTOTROPHY (from CARBON DIOXIDE). They can also be classified by whether or not they stain (based on the structure of their CELL WALLS) with CRYSTAL VIOLET dye: gram-negative or gram-positive.
Process by which organic tissue becomes hardened by the physiologic deposit of calcium salts.
A clinical syndrome associated with the retention of renal waste products or uremic toxins in the blood. It is usually the result of RENAL INSUFFICIENCY. Most uremic toxins are end products of protein or nitrogen CATABOLISM, such as UREA or CREATININE. Severe uremia can lead to multiple organ dysfunctions with a constellation of symptoms.
Measurement and evaluation of the components of substances to be taken as FOOD.
Inland bodies of still or slowly moving FRESH WATER or salt water, larger than a pond, and supplied by RIVERS and streams.
Polyamines are organic compounds with more than one amino group, involved in various biological processes such as cell growth, differentiation, and apoptosis, and found to be increased in certain diseases including cancer.
The gaseous envelope surrounding a planet or similar body. (From Random House Unabridged Dictionary, 2d ed)
The science of the earth and other celestial bodies and their history as recorded in the rocks. It includes the study of geologic processes of an area such as rock formations, weathering and erosion, and sedimentation. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
A group of chemical elements that are needed in minute quantities for the proper growth, development, and physiology of an organism. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
A chemical reaction in which an electron is transferred from one molecule to another. The electron-donating molecule is the reducing agent or reductant; the electron-accepting molecule is the oxidizing agent or oxidant. Reducing and oxidizing agents function as conjugate reductant-oxidant pairs or redox pairs (Lehninger, Principles of Biochemistry, 1982, p471).
High molecular weight polymers containing a mixture of purine and pyrimidine nucleotides chained together by ribose or deoxyribose linkages.
Derivatives of ACETIC ACID. Included under this heading are a broad variety of acid forms, salts, esters, and amides that contain the carboxymethane structure.
Body organ that filters blood for the secretion of URINE and that regulates ion concentrations.
Substances capable of inhibiting, retarding or arresting the process of fermentation, acidification or other deterioration of foods.
The facilitation of a chemical reaction by material (catalyst) that is not consumed by the reaction.
A condition of abnormally elevated output of PARATHYROID HORMONE (or PTH) triggering responses that increase blood CALCIUM. It is characterized by HYPERCALCEMIA and BONE RESORPTION, eventually leading to bone diseases. PRIMARY HYPERPARATHYROIDISM is caused by parathyroid HYPERPLASIA or PARATHYROID NEOPLASMS. SECONDARY HYPERPARATHYROIDISM is increased PTH secretion in response to HYPOCALCEMIA, usually caused by chronic KIDNEY DISEASES.
Unstable isotopes of carbon that decay or disintegrate emitting radiation. C atoms with atomic weights 10, 11, and 14-16 are radioactive carbon isotopes.
Chromatographic techniques in which the mobile phase is a liquid.
The salinated water of OCEANS AND SEAS that provides habitat for marine organisms.

Accumulation of N-acyl-ethanolamine phospholipids in rat brains during post-decapitative ischemia: a 31p NMR study. (1/1206)

Phosphorus-31 nuclear magnetic resonance (31P NMR) spectroscopy has been used to study accumulation of N-acyl-ethanolamine phospholipids in rat brains during post-decapitative ischemia. Lipids were extracted from rat brain homogenates and the extracts were thoroughly washed with aq. potassium ethylenediaminetetraacetic acid (EDTA). The lower organic phases were isolated and evaporated to dryness under a stream of nitrogen and the lipids were redissolved in CDCl3-CH3OH-H2O 100.0:29.9:5.2 (v/v/v) for NMR analysis. Increasing the period of post-decapitative ischemia resulted in an accumulation of two signals in the NMR spectra at 0.18 and 0.22 ppm (relative to the chemical shift of 1,2-diacyl-sn-glycero-3-phosphocholine (PCDIACYL) at -0.84 ppm). These signals were identified as originating from 1,2-diacyl-sn-glycero-3-phospho-(N-acyl)-ethanolamine (NAPEDIACYL) and 1-(1'-alkenyl)-2-acyl-sn -glycero-3-phospho-(N-acyl)-ethanolamine (NAPEPLAS), respectively, by spiking with authentic materials. Additionally, the identification was verified by thin-layer chromatography, which also showed the accumulation of N-acyl-ethanolamine phospholipids. The use of K-EDTA instead of the commonly used Cs-EDTA in the preparation of the NMR samples allowed the separation of the chemical shifts of N-acyl-ethanolamine phospholipids from those of the ethanolamine phospholipids. Moreover, the chemical shift of cardiolipin was moved from 0.15 ppm observed with Cs-EDTA to about 0.31 ppm with K-EDTA. The present study demonstrates that it is possible to detect and quantify post-decapitative accumulation of NAPE subclasses (NAPEDIACYL and NAPEPLAS) in rat brains by the use of 31P NMR spectroscopy.  (+info)

SVPD-post-labeling detection of oxidative damage negates the problem of adventitious oxidative effects during 32P-labeling. (2/1206)

The exploitation of oxidative DNA lesions as biomarkers of oxidative stress in vivo requires techniques that allow for the precise and valid measurement of oxidative damage to DNA. Previously, endogenous levels of the oxidative lesion 8-hydroxy-2'-deoxyguanosine (8-HO-dG) in rat tissues determined by a micrococcal nuclease/calf spleen phosphodiesterase-based 32P-post-labeling protocol were found to be at least 10-fold higher than those determined by HPLC with electrochemical detection. This was attributed to the adventitious oxidation of the normal nucleotides (dGp) occurring during the labeling stage of the postlabeling protocol, which could only be prevented by the introduction of additional chromatographic steps to remove the unmodified species prior to labeling. In the present study we report that an alternative snake venom phosphodiesterase-based 32P-post-labeling procedure (SVPD-postlabeling) negates the problem of adventitious oxidative damage during labeling by virtue of a unique digestion strategy. In SVPD-post-labeling, digestion yields certain lesions (thymine glycols, phosphoglycolates and abasic sites) as damage-containing dimer species which are ready substrates for labeling. In contrast, the undamaged DNA is recovered as mononucleoside species (dN) which are not substrates for labeling and so remain undetected. Furthermore, even if the mononucleosides are oxidized during labeling, they will not contribute to the level of damage detected. Indeed, we demonstrate that neither the external gamma-irradiation of the digested DNA samples nor increasing the incubation time of the labeling reaction alters the levels of damage detected by SVPD-post-labeling. The negation of adventitious oxidative effects during labeling deems that an optimized SVPD-post-labeling procedure should be well-suited for the biomonitoring of endogenous oxidative stress in vivo.  (+info)

Thermodynamic and kinetic characterization of the interaction between the Ras binding domain of AF6 and members of the Ras subfamily. (3/1206)

Cellular signaling downstream of Ras is highly diversified and may involve many different effector molecules. A potential candidate is AF6 which was originally identified as a fusion to ALL-1 in acute myeloid leukemia. In the present work the interaction between Ras and AF6 is characterized and compared with other effectors. The binding characteristics are quite similar to Raf and RalGEF, i.e. nucleotide dissociation as well as GTPase-activating protein activity are inhibited, whereas the intrinsic GTPase activity of Ras is unperturbed by AF6 binding. Particularly, the dynamics of interaction are similar to Raf and RalGEF with a lifetime of the Ras. AF6 complex in the millisecond range. As probed by 31P NMR spectroscopy one of two major conformational states of Ras is stabilized by the interaction with AF6. Looking at the affinities of AF6 to a number of Ras mutants in the effector region, a specificity profile emerges distinct from that of other effector molecules. This finding may be useful in defining the biological function of AF6 by selectively switching off other pathways downstream of Ras using the appropriate effector mutant. Notably, among the Ras-related proteins AF6 binds most tightly to Rap1A which could imply a role of Rap1A in AF6 regulation.  (+info)

Hypoperfusion-induced contractile failure does not require changes in cardiac energetics. (4/1206)

Decreasing coronary perfusion causes an immediate decrease in contractile function via unknown mechanisms. It has long been suspected that this contractile dysfunction is caused by ischemia-induced changes in cardiac energetics. Our goal was to determine whether changes in cardiac energetics necessarily precede the contractile dysfunction as one would expect if a causal relationship exists. In 14 isolated rat hearts, we gradually decreased coronary perfusion using a coronary perfusate with a normal hematocrit and normal concentrations of the major metabolic substrates. Using 31P NMR spectroscopy to measure ATP, phosphocreatine (PCr), Pi, and ADP concentrations ([ATP], [PCr], [Pi], [ADP]), pH, and amount of free energy released from ATP hydrolysis (|DeltaGATP|), we found that none of these variables changed significantly until several minutes after systolic pressure had significantly decreased. Even when developed pressure had decreased by over one-third, only very slight changes in [Pi], pH, and |DeltaGATP| had occurred, with no significant changes in [ATP], [PCr], or [ADP]. Additionally, the rate of high-energy phosphate transfer between ATP and PCr did not decrease enough during hypoperfusion to explain the contractile dysfunction. We conclude that nonenergetic factors are the dominant cause of the initial decrease in systolic function when myocardial perfusion is decreased.  (+info)

Fibrin microbeads (FMB) as biodegradable carriers for culturing cells and for accelerating wound healing. (5/1206)

We have developed biodegradable fibrin-derived microbeads as potent cell carriers. The fibrin-derived microbeads, 50-200 microm in diameter, were tested for their attachment to a wide range of cell types. Fibrin-derived microbeads were shown to be greatly haptotactic to cells (such as endothelial cells, smooth muscle cells and fibroblasts), which respond to fibrinogen in contrast to keratinocytes and different cell lines derived from leukocytic lineage. The cells on fibrin-derived microbeads could be maintained for more than 10 d and achieved a high density. 31P-nuclear magnetic resonance was employed to monitor phosphate metabolism in cells, with densities on the order of 100 million cells per g of fibrin-derived microbeads. The 31P-nuclear magnetic resonance adenosine triphosphate and phosphocreatine signals, equivalent to the signal obtained with perfused normal skin, indicated that metabolism of cells on fibrin-derived microbeads was responsive to oxygenation and nutrients. Light, fluorescent, and confocal laser microscopy revealed that the porous fibrin-derived microbeads accommodate up to 200-300 cells due to their high surface area which minimized contact inhibition. Cells could degrade the fibrin-derived microbeads and be transferred to seed culture flasks without trypsinization. In a pig skin wound healing model, fibrin-derived microbeads + fibroblasts were transplanted into full thickness punch wounds. This procedure was compared with other treatment modalities, such as the addition of human platelet-derived growth factor BB or fibrin-derived microbeads alone. By the third day after wounding, only the wounds in which fibroblasts on fibrin-derived microbeads were added showed significant formation of granulation tissue. Based on the above, we project many uses of our novel fibrin-derived microbead technology for cell culturing, wound healing and tissue engineering.  (+info)

Evaluation of the effects of photodynamic therapy with phosphorus 31 magnetic resonance spectroscopy. (6/1206)

Magnetic resonance spectroscopy in situ was used to study changes in phosphorus 31 metabolism after photodynamic therapy (PDT) of transplanted HeLa cell tumours. Tumours were irradiated 2 h after administration of ATX-S10 (8-formyloximethylidene-7-hydroxy-3-ethenyl-2,7,12,18, tetramethyl-porphyrin-13,17-bispropionil aspartate), a new photosensitizer and chlorin derivative. Nuclear magnetic resonance spectra were measured prior to illumination and 1, 3, 7, 14, 21 and 28 days after PDT on each mouse. A drastic decrease in adenosine triphosphate (ATP) and a concomitant increase in inorganic phosphate (Pi) were evident on the first day after PDT in all cases. The beta-ATP/total phosphate (P) ratio was 0.64 +/- 0.29% (average +/- s.d.) in complete response, 0.67 +/- 0.30% in recurrence and 2.45 +/- 0.93% in partial response. Comparison of this ratio to the histological findings revealed that the beta-ATP/total P ratio reflects the HeLa cell tumours which survived PDT. In other words, partial response on the one hand was distinguished from complete response and recurrence on the other with this ratio 1 day after PDT (P < 0.05). In addition, the ratio of phosphomonoester (PME) to Pi rose beyond 1.0 when macroscopic recurrence occurred, while it stayed under 1.0 in complete response. This finding suggests that the recurrence of HeLa cell tumours can be detected by the PME/Pi ratio.  (+info)

Effect of an endothelin receptor antagonist and an angiotensin converting enzyme inhibitor on metabolism and contraction in the ischemic and reperfused rabbit heart. (7/1206)

The effect of an endothelin (ET) A/ETB receptor antagonist, TAK-044, and/or an angiotensin converting enzyme (ACE) inhibitor, temocaprilat, on myocardial metabolism and contraction during ischemia and reperfusion was examined by phosphorus 31-nuclear magnetic resonance (31P-NMR) in Langendorff rabbit hearts. After normothermic 15 min global ischemia, 60min of postischemic reperfusion was carried out. TAK-044 and/or temocaprilat was administered from 40 min prior to the global ischemia. Adenosine triphosphate (ATP), creatine phosphate, inorganic phosphate, pH, left ventricular systolic developed pressure (LVDev.P), left ventricular end-diastolic pressure (LVEDP) and coronary flow were measured. Twenty-eight hearts were divided into 4 experimental groups consisted of seven hearts each: Group I consisted of controls, Group II was perfused with TAK-044 (10(-6) mol/L), Group III was perfused with temocaprilat (10(-6) mol/L), and Group IV was perfused with TAK-044 (10(-6) mol/L) in combination with temocaprilat (10(-6) mol/L). Group II showed a more early recovery of ATP during postischemic reperfusion (82+/-3%) compared with Group I (71+/-3%). Group III showed a significant inhibition of the decrease in ATP during global ischemia (54+/-3%) compared with Group I (45+/-3%). Group IV also showed a significant marked inhibition of the decrease in ATP during global ischemia (59+/-5%) and a more significant improvement on recovery of ATP during postischemic reperfusion (86+/-3%) compared with the other 3 groups. There were no differences in LVDev.P, LVEDP and coronary flow among these groups. In conclusion, TAK-044 in combination with temocaprilat had a significant potentiation on myocardial metabolism during both ischemia and reperfusion.  (+info)

Static and magic angle spinning (31)P NMR spectroscopy of two natural plasma membranes. (8/1206)

Static and magic angle spinning (31)P NMR spectroscopy was used for the first time in natural plasma membranes from erythrocytes and skeletal muscle to study phospholipid arrangement and composition. Typical static powder-like spectra were obtained showing that phospholipids were in a bilayer arrangement. Magic angle spinning narrowed spectra into two components. The first one corresponded to phosphatidylcholine and the second one to the other phospholipids with intensities in agreement with the known phospholipid composition. These findings show that NMR data previously acquired using model membranes can be transposed to studies on phospholipids in their natural environment.  (+info)

Phosphorus is an essential mineral that is required by every cell in the body for normal functioning. It is a key component of several important biomolecules, including adenosine triphosphate (ATP), which is the primary source of energy for cells, and deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), which are the genetic materials in cells.

Phosphorus is also a major constituent of bones and teeth, where it combines with calcium to provide strength and structure. In addition, phosphorus plays a critical role in various metabolic processes, including energy production, nerve impulse transmission, and pH regulation.

The medical definition of phosphorus refers to the chemical element with the atomic number 15 and the symbol P. It is a highly reactive non-metal that exists in several forms, including white phosphorus, red phosphorus, and black phosphorus. In the body, phosphorus is primarily found in the form of organic compounds, such as phospholipids, phosphoproteins, and nucleic acids.

Abnormal levels of phosphorus in the body can lead to various health problems. For example, high levels of phosphorus (hyperphosphatemia) can occur in patients with kidney disease or those who consume large amounts of phosphorus-rich foods, and can contribute to the development of calcification of soft tissues and cardiovascular disease. On the other hand, low levels of phosphorus (hypophosphatemia) can occur in patients with malnutrition, vitamin D deficiency, or alcoholism, and can lead to muscle weakness, bone pain, and an increased risk of infection.

Phosphorus isotopes are different forms of the element phosphorus that have different numbers of neutrons in their atomic nuclei, while the number of protons remains the same. The most common and stable isotope of phosphorus is 31P, which contains 15 protons and 16 neutrons. However, there are also several other isotopes of phosphorus that exist, including 32P and 33P, which are radioactive and have 15 protons and 17 or 18 neutrons, respectively. These radioactive isotopes are often used in medical research and treatment, such as in the form of radiopharmaceuticals to diagnose and treat various diseases.

Isotopes are variants of a chemical element that have the same number of protons in their atomic nucleus, but a different number of neutrons. This means they have different atomic masses, but share similar chemical properties. Some isotopes are stable and do not decay naturally, while others are unstable and radioactive, undergoing radioactive decay and emitting radiation in the process. These radioisotopes are often used in medical imaging and treatment procedures.

Dietary Phosphorus is a mineral that is an essential nutrient for human health. It is required for the growth, maintenance, and repair of body tissues, including bones and teeth. Phosphorus is also necessary for the production of energy, the formation of DNA and RNA, and the regulation of various physiological processes.

In the diet, phosphorus is primarily found in protein-containing foods such as meat, poultry, fish, dairy products, legumes, and nuts. It can also be found in processed foods that contain additives such as phosphoric acid, which is used to enhance flavor or as a preservative.

The recommended daily intake of phosphorus for adults is 700 milligrams (mg) per day. However, it's important to note that excessive intake of phosphorus, particularly from supplements and fortified foods, can lead to health problems such as kidney damage and calcification of soft tissues. Therefore, it's recommended to obtain phosphorus primarily from whole foods rather than supplements.

Isotope labeling is a scientific technique used in the field of medicine, particularly in molecular biology, chemistry, and pharmacology. It involves replacing one or more atoms in a molecule with a radioactive or stable isotope of the same element. This modified molecule can then be traced and analyzed to study its structure, function, metabolism, or interaction with other molecules within biological systems.

Radioisotope labeling uses unstable radioactive isotopes that emit radiation, allowing for detection and quantification of the labeled molecule using various imaging techniques, such as positron emission tomography (PET) or single-photon emission computed tomography (SPECT). This approach is particularly useful in tracking the distribution and metabolism of drugs, hormones, or other biomolecules in living organisms.

Stable isotope labeling, on the other hand, employs non-radioactive isotopes that do not emit radiation. These isotopes have different atomic masses compared to their natural counterparts and can be detected using mass spectrometry. Stable isotope labeling is often used in metabolic studies, protein turnover analysis, or for identifying the origin of specific molecules within complex biological samples.

In summary, isotope labeling is a versatile tool in medical research that enables researchers to investigate various aspects of molecular behavior and interactions within biological systems.

Oxygen isotopes are different forms or varieties of the element oxygen that have the same number of protons in their atomic nuclei, which is 8, but a different number of neutrons. The most common oxygen isotopes are oxygen-16 (^{16}O), which contains 8 protons and 8 neutrons, and oxygen-18 (^{18}O), which contains 8 protons and 10 neutrons.

The ratio of these oxygen isotopes can vary in different substances, such as water molecules, and can provide valuable information about the origins and history of those substances. For example, scientists can use the ratio of oxygen-18 to oxygen-16 in ancient ice cores or fossilized bones to learn about past climate conditions or the diets of ancient organisms.

In medical contexts, oxygen isotopes may be used in diagnostic tests or treatments, such as positron emission tomography (PET) scans, where a radioactive isotope of oxygen (such as oxygen-15) is introduced into the body and emits positrons that can be detected by specialized equipment to create detailed images of internal structures.

Nitrogen isotopes are different forms of the nitrogen element (N), which have varying numbers of neutrons in their atomic nuclei. The most common nitrogen isotope is N-14, which contains 7 protons and 7 neutrons in its nucleus. However, there are also heavier stable isotopes such as N-15, which contains one extra neutron.

In medical terms, nitrogen isotopes can be used in research and diagnostic procedures to study various biological processes. For example, N-15 can be used in a technique called "nitrogen-15 nuclear magnetic resonance (NMR) spectroscopy" to investigate the metabolism of nitrogen-containing compounds in the body. Additionally, stable isotope labeling with nitrogen-15 has been used in clinical trials and research studies to track the fate of drugs and nutrients in the body.

In some cases, radioactive nitrogen isotopes such as N-13 or N-16 may also be used in medical imaging techniques like positron emission tomography (PET) scans to visualize and diagnose various diseases and conditions. However, these applications are less common than the use of stable nitrogen isotopes.

Carbon isotopes are variants of the chemical element carbon that have different numbers of neutrons in their atomic nuclei. The most common and stable isotope of carbon is carbon-12 (^{12}C), which contains six protons and six neutrons. However, carbon can also come in other forms, known as isotopes, which contain different numbers of neutrons.

Carbon-13 (^{13}C) is a stable isotope of carbon that contains seven neutrons in its nucleus. It makes up about 1.1% of all carbon found on Earth and is used in various scientific applications, such as in tracing the metabolic pathways of organisms or in studying the age of fossilized materials.

Carbon-14 (^{14}C), also known as radiocarbon, is a radioactive isotope of carbon that contains eight neutrons in its nucleus. It is produced naturally in the atmosphere through the interaction of cosmic rays with nitrogen gas. Carbon-14 has a half-life of about 5,730 years, which makes it useful for dating organic materials, such as archaeological artifacts or fossils, up to around 60,000 years old.

Carbon isotopes are important in many scientific fields, including geology, biology, and medicine, and are used in a variety of applications, from studying the Earth's climate history to diagnosing medical conditions.

Phosphorus compounds refer to chemical substances that contain phosphorus (P) combined with one or more other elements. Phosphorus can form a variety of compounds due to its ability to exist in several oxidation states, most commonly +3 and +5.

In biological systems, phosphorus is an essential element for life, playing crucial roles in energy transfer, metabolism, and structural components of cells. Some common examples of phosphorus compounds include:

1. Phosphoric acid (H3PO4): A weak triprotic acid that forms salts called phosphates when combined with metal ions or basic radicals.
2. Phosphates (PO4^3-): The salt or ester form of phosphoric acid, widely found in nature and essential for various biological processes such as bone formation, energy metabolism, and nucleic acid synthesis.
3. Phosphorus pentachloride (PCl5): A pungent, white crystalline solid used in organic chemistry as a chlorinating agent.
4. Phosphorus trichloride (PCl3): A colorless liquid with a suffocating odor, used in the production of various chemical compounds, including pharmaceuticals and agrochemicals.
5. Dicalcium phosphate (CaHPO4): A calcium salt of phosphoric acid, commonly found in mineral supplements and used as a dietary supplement for animals and humans.
6. Adenosine triphosphate (ATP): A high-energy molecule that stores and transfers energy within cells, playing a critical role in metabolic processes such as muscle contraction and biosynthesis.

Phosphorus compounds have numerous applications across various industries, including agriculture, food processing, pharmaceuticals, and chemical manufacturing.

Zinc isotopes refer to variants of the chemical element zinc, each with a different number of neutrons in their atomic nucleus. Zinc has five stable isotopes: zinc-64, zinc-66, zinc-67, zinc-68, and zinc-70. These isotopes have naturally occurring abundances that vary, with zinc-64 being the most abundant at approximately 48.6%.

Additionally, there are also several radioactive isotopes of zinc, including zinc-65, zinc-71, and zinc-72, among others. These isotopes have unstable nuclei that decay over time, emitting radiation in the process. They are not found naturally on Earth and must be produced artificially through nuclear reactions.

Medical Definition: Zinc isotopes refer to variants of the chemical element zinc with different numbers of neutrons in their atomic nucleus, including stable isotopes such as zinc-64, zinc-66, zinc-67, zinc-68, and zinc-70, and radioactive isotopes such as zinc-65, zinc-71, and zinc-72.

Phosphates, in a medical context, refer to the salts or esters of phosphoric acid. Phosphates play crucial roles in various biological processes within the human body. They are essential components of bones and teeth, where they combine with calcium to form hydroxyapatite crystals. Phosphates also participate in energy transfer reactions as phosphate groups attached to adenosine diphosphate (ADP) and adenosine triphosphate (ATP). Additionally, they contribute to buffer systems that help maintain normal pH levels in the body.

Abnormal levels of phosphates in the blood can indicate certain medical conditions. High phosphate levels (hyperphosphatemia) may be associated with kidney dysfunction, hyperparathyroidism, or excessive intake of phosphate-containing products. Low phosphate levels (hypophosphatemia) might result from malnutrition, vitamin D deficiency, or certain diseases affecting the small intestine or kidneys. Both hypophosphatemia and hyperphosphatemia can have significant impacts on various organ systems and may require medical intervention.

Sulfur isotopes are different forms of the chemical element sulfur, each with a distinct number of neutrons in their atomic nuclei. The most common sulfur isotopes are sulfur-32 (with 16 neutrons) and sulfur-34 (with 18 neutrons). These isotopes have similar chemical properties but different atomic masses, which can be used to trace the movement and cycling of sulfur through various environmental processes, such as volcanic emissions, bacterial metabolism, and fossil fuel combustion. The relative abundances of sulfur isotopes can also provide information about the origins and history of sulfur-containing minerals and compounds.

Phosphorus metabolism disorders refer to a group of conditions that affect the body's ability to properly regulate the levels and utilization of phosphorus. Phosphorus is an essential mineral that plays a critical role in many biological processes, including energy production, bone formation, and nerve function.

Disorders of phosphorus metabolism can result from genetic defects, kidney dysfunction, vitamin D deficiency, or other medical conditions. These disorders can lead to abnormal levels of phosphorus in the blood, which can cause a range of symptoms, including muscle weakness, bone pain, seizures, and respiratory failure.

Examples of phosphorus metabolism disorders include:

1. Hypophosphatemia: This is a condition characterized by low levels of phosphorus in the blood. It can be caused by various factors, such as malnutrition, vitamin D deficiency, and kidney dysfunction.
2. Hyperphosphatemia: This is a condition characterized by high levels of phosphorus in the blood. It can be caused by kidney failure, tumor lysis syndrome, and certain medications.
3. Hereditary hypophosphatemic rickets: This is a genetic disorder that affects the body's ability to regulate vitamin D and phosphorus metabolism. It can lead to weakened bones and skeletal deformities.
4. Oncogenic osteomalacia: This is a rare condition that occurs when tumors produce substances that interfere with phosphorus metabolism, leading to bone pain and weakness.

Treatment for phosphorus metabolism disorders depends on the underlying cause of the disorder and may include dietary changes, supplements, medications, or surgery.

Deuterium is a stable and non-radioactive isotope of hydrogen. The atomic nucleus of deuterium, called a deuteron, contains one proton and one neutron, giving it an atomic weight of approximately 2.014 atomic mass units (amu). It is also known as heavy hydrogen or heavy water because its hydrogen atoms contain one neutron in addition to the usual one proton found in common hydrogen atoms.

Deuterium occurs naturally in trace amounts in water and other organic compounds, typically making up about 0.015% to 0.018% of all hydrogen atoms. It can be separated from regular hydrogen through various methods such as electrolysis or distillation, and it has many applications in scientific research, particularly in the fields of chemistry and physics.

In medical contexts, deuterium is sometimes used as a tracer to study metabolic processes in the body. By replacing hydrogen atoms in specific molecules with deuterium atoms, researchers can track the movement and transformation of those molecules within living organisms. This technique has been used to investigate various physiological processes, including drug metabolism, energy production, and lipid synthesis.

I must clarify that "Iron Isotopes" is not a medical term, but rather a scientific concept from the field of physics and chemistry. However, I can certainly provide a general explanation of isotopes and then focus on iron isotopes specifically.

An isotope is a variant of a chemical element that has the same number of protons (and thus the same atomic number) but a different number of neutrons within its nucleus. This results in variations of the atomic mass of isotopes of the same element. Some isotopes are stable, while others are unstable and will decay over time into other elements or isotopes, a process called radioactive decay.

Iron (Fe) has four naturally occurring stable isotopes: Fe-54, Fe-56, Fe-57, and Fe-58. These iron isotopes have different numbers of neutrons in their nuclei, resulting in slightly different atomic masses. The most abundant iron isotope is Fe-56, which contains 26 protons and 30 neutrons in its nucleus.

In the context of human health, iron is an essential nutrient that plays a crucial role in various biological processes, such as oxygen transport and energy production. However, the concept of iron isotopes does not have a direct medical relevance, but it can be useful in scientific research related to fields like geochemistry, environmental science, or nuclear physics.

6-Phytase is an enzyme that catalyzes the hydrolysis of phytic acid (myo-inositol hexakisphosphate), a major storage form of phosphorus in plants, into inorganic phosphate and lower molecular weight myo-inositol phosphates. This enzymatic reaction releases phosphate and micronutrients, making them more available for absorption in the gastrointestinal tract of monogastric animals, such as pigs, poultry, and fish. The "6" in 6-Phytase refers to the position of the phosphate group that is cleaved from the myo-inositol ring. This enzyme has significant applications in animal nutrition and feed industry to improve nutrient utilization and reduce phosphorus pollution in the environment.

In the context of nutrition and health, minerals are inorganic elements that are essential for various bodily functions, such as nerve impulse transmission, muscle contraction, maintaining fluid and electrolyte balance, and bone structure. They are required in small amounts compared to macronutrients (carbohydrates, proteins, and fats) and are obtained from food and water.

Some of the major minerals include calcium, phosphorus, magnesium, sodium, potassium, and chloride, while trace minerals or microminerals are required in even smaller amounts and include iron, zinc, copper, manganese, iodine, selenium, and fluoride.

It's worth noting that the term "minerals" can also refer to geological substances found in the earth, but in medical terminology, it specifically refers to the essential inorganic elements required for human health.

Nitrogen is not typically referred to as a medical term, but it is an element that is crucial to medicine and human life.

In a medical context, nitrogen is often mentioned in relation to gas analysis, respiratory therapy, or medical gases. Nitrogen (N) is a colorless, odorless, and nonreactive gas that makes up about 78% of the Earth's atmosphere. It is an essential element for various biological processes, such as the growth and maintenance of organisms, because it is a key component of amino acids, nucleic acids, and other organic compounds.

In some medical applications, nitrogen is used to displace oxygen in a mixture to create a controlled environment with reduced oxygen levels (hypoxic conditions) for therapeutic purposes, such as in certain types of hyperbaric chambers. Additionally, nitrogen gas is sometimes used in cryotherapy, where extremely low temperatures are applied to tissues to reduce pain, swelling, and inflammation.

However, it's important to note that breathing pure nitrogen can be dangerous, as it can lead to unconsciousness and even death due to lack of oxygen (asphyxiation) within minutes.

Parathyroid hormone (PTH) is a polypeptide hormone that plays a crucial role in the regulation of calcium and phosphate levels in the body. It is produced and secreted by the parathyroid glands, which are four small endocrine glands located on the back surface of the thyroid gland.

The primary function of PTH is to maintain normal calcium levels in the blood by increasing calcium absorption from the gut, mobilizing calcium from bones, and decreasing calcium excretion by the kidneys. PTH also increases phosphate excretion by the kidneys, which helps to lower serum phosphate levels.

In addition to its role in calcium and phosphate homeostasis, PTH has been shown to have anabolic effects on bone tissue, stimulating bone formation and preventing bone loss. However, chronic elevations in PTH levels can lead to excessive bone resorption and osteoporosis.

Overall, Parathyroid Hormone is a critical hormone that helps maintain mineral homeostasis and supports healthy bone metabolism.

Hyperphosphatemia is a medical condition characterized by an excessively high level of phosphate (a form of the chemical element phosphorus) in the blood. Phosphate is an important component of various biological molecules, such as DNA, RNA, and ATP, and it plays a crucial role in many cellular processes, including energy metabolism and signal transduction.

In healthy individuals, the concentration of phosphate in the blood is tightly regulated within a narrow range to maintain normal physiological functions. However, when the phosphate level rises above this range (typically defined as a serum phosphate level greater than 4.5 mg/dL or 1.46 mmol/L), it can lead to hyperphosphatemia.

Hyperphosphatemia can result from various underlying medical conditions, including:

* Kidney dysfunction: The kidneys are responsible for filtering excess phosphate out of the blood and excreting it in the urine. When the kidneys fail to function properly, they may be unable to remove enough phosphate, leading to its accumulation in the blood.
* Hypoparathyroidism: The parathyroid glands produce a hormone called parathyroid hormone (PTH), which helps regulate calcium and phosphate levels in the body. In hypoparathyroidism, the production of PTH is insufficient, leading to an increase in phosphate levels.
* Hyperparathyroidism: In contrast, excessive production of PTH can also lead to hyperphosphatemia by increasing the release of phosphate from bones and decreasing its reabsorption in the kidneys.
* Excessive intake of phosphate-rich foods or supplements: Consuming large amounts of phosphate-rich foods, such as dairy products, nuts, and legumes, or taking phosphate supplements can raise blood phosphate levels.
* Tumor lysis syndrome: This is a complication that can occur after the treatment of certain types of cancer, particularly hematological malignancies. The rapid destruction of cancer cells releases large amounts of intracellular contents, including phosphate, into the bloodstream, leading to hyperphosphatemia.
* Rhabdomyolysis: This is a condition in which muscle tissue breaks down, releasing its contents, including phosphate, into the bloodstream. It can be caused by various factors, such as trauma, infection, or drug toxicity.

Hyperphosphatemia can have several adverse effects on the body, including calcification of soft tissues, kidney damage, and metabolic disturbances. Therefore, it is essential to diagnose and manage hyperphosphatemia promptly to prevent complications. Treatment options may include dietary modifications, medications that bind phosphate in the gastrointestinal tract, and dialysis in severe cases.

Dietary calcium is a type of calcium that is obtained through food sources. Calcium is an essential mineral that is necessary for many bodily functions, including bone formation and maintenance, muscle contraction, nerve impulse transmission, and blood clotting.

The recommended daily intake of dietary calcium varies depending on age, sex, and other factors. For example, the recommended daily intake for adults aged 19-50 is 1000 mg, while women over 50 and men over 70 require 1200 mg per day.

Good dietary sources of calcium include dairy products such as milk, cheese, and yogurt; leafy green vegetables like broccoli and kale; fortified cereals and juices; and certain types of fish, such as salmon and sardines. It is important to note that some foods can inhibit the absorption of calcium, including oxalates found in spinach and rhubarb, and phytates found in whole grains and legumes.

If a person is unable to get enough calcium through their diet, they may need to take calcium supplements. However, it is important to talk to a healthcare provider before starting any new supplement regimen, as excessive intake of calcium can lead to negative health effects.

Strontium isotopes are different forms of the element strontium that have different numbers of neutrons in their atomic nuclei. The most common strontium isotopes are Sr-84, Sr-86, Sr-87, and Sr-88, with atomic masses of 83.913, 85.909, 86.909, and 87.905 atomic mass units (amu), respectively.

Strontium-87 is a radioactive isotope that is produced naturally in the Earth's crust through the decay of rubidium-87. The ratio of strontium-87 to strontium-86 can be used as a geological dating tool, as well as a forensic tool for determining the origin of objects or materials.

In medical applications, strontium ranelate, which contains stable strontium isotopes, has been used in the treatment of osteoporosis due to its ability to increase bone density and reduce the risk of fractures. However, its use has been limited due to concerns about potential side effects, including cardiovascular risks.

Calcium is an essential mineral that is vital for various physiological processes in the human body. The medical definition of calcium is as follows:

Calcium (Ca2+) is a crucial cation and the most abundant mineral in the human body, with approximately 99% of it found in bones and teeth. It plays a vital role in maintaining structural integrity, nerve impulse transmission, muscle contraction, hormonal secretion, blood coagulation, and enzyme activation.

Calcium homeostasis is tightly regulated through the interplay of several hormones, including parathyroid hormone (PTH), calcitonin, and vitamin D. Dietary calcium intake, absorption, and excretion are also critical factors in maintaining optimal calcium levels in the body.

Hypocalcemia refers to low serum calcium levels, while hypercalcemia indicates high serum calcium levels. Both conditions can have detrimental effects on various organ systems and require medical intervention to correct.

I'm sorry for any confusion, but "soil" is not a term that has a medical definition. Soil is defined as the top layer of earth in which plants grow, a mixture of organic material, clay, sand, and silt. If you have any questions related to medicine or health, I would be happy to try to help answer them for you.

Eutrophication is the process of excessive nutrient enrichment in bodies of water, which can lead to a rapid growth of aquatic plants and algae. This overgrowth can result in decreased levels of oxygen in the water, harming or even killing fish and other aquatic life. The primary cause of eutrophication is the addition of nutrients, particularly nitrogen and phosphorus, from human activities such as agricultural runoff, sewage and wastewater discharge, and air pollution.

In advanced stages, eutrophication can lead to a shift in the dominant species in the aquatic ecosystem, favoring those that are better adapted to the high-nutrient conditions. This can result in a loss of biodiversity and changes in water quality, making it difficult for many organisms to survive.

Eutrophication is a significant global environmental problem, affecting both freshwater and marine ecosystems. It can lead to harmful algal blooms (HABs), which can produce toxins that are dangerous to humans and animals. In addition, eutrophication can impact water use for drinking, irrigation, recreation, and industry, making it a critical issue for public health and economic development.

The Radioisotope Dilution Technique is a method used in nuclear medicine to measure the volume and flow rate of a particular fluid in the body. It involves introducing a known amount of a radioactive isotope, or radioisotope, into the fluid, such as blood. The isotope mixes with the fluid, and samples are then taken from the fluid at various time points.

By measuring the concentration of the radioisotope in each sample, it is possible to calculate the total volume of the fluid based on the amount of the isotope introduced and the dilution factor. The flow rate can also be calculated by measuring the concentration of the isotope over time and using the formula:

Flow rate = Volume/Time

This technique is commonly used in medical research and clinical settings to measure cardiac output, cerebral blood flow, and renal function, among other applications. It is a safe and reliable method that has been widely used for many years. However, it does require the use of radioactive materials and specialized equipment, so it should only be performed by trained medical professionals in appropriate facilities.

Phytic acid, also known as phytate in its salt form, is a natural substance found in plant-based foods such as grains, legumes, nuts, and seeds. It's a storage form of phosphorus for the plant and is often referred to as an "anti-nutrient" because it can bind to certain minerals like calcium, iron, magnesium, and zinc in the gastrointestinal tract and prevent their absorption. This can potentially lead to mineral deficiencies if a diet is consistently high in phytic acid-rich foods and low in mineral-rich foods. However, it's important to note that phytic acid also has antioxidant properties and may have health benefits when consumed as part of a balanced diet.

The bioavailability of minerals from phytic acid-rich foods can be improved through various methods such as soaking, sprouting, fermenting, or cooking, which can help break down some of the phytic acid and release the bound minerals.

Magnetic Resonance Spectroscopy (MRS) is a non-invasive diagnostic technique that provides information about the biochemical composition of tissues, including their metabolic state. It is often used in conjunction with Magnetic Resonance Imaging (MRI) to analyze various metabolites within body tissues, such as the brain, heart, liver, and muscles.

During MRS, a strong magnetic field, radio waves, and a computer are used to produce detailed images and data about the concentration of specific metabolites in the targeted tissue or organ. This technique can help detect abnormalities related to energy metabolism, neurotransmitter levels, pH balance, and other biochemical processes, which can be useful for diagnosing and monitoring various medical conditions, including cancer, neurological disorders, and metabolic diseases.

There are different types of MRS, such as Proton (^1^H) MRS, Phosphorus-31 (^31^P) MRS, and Carbon-13 (^13^C) MRS, each focusing on specific elements or metabolites within the body. The choice of MRS technique depends on the clinical question being addressed and the type of information needed for diagnosis or monitoring purposes.

A diet, in medical terms, refers to the planned and regular consumption of food and drinks. It is a balanced selection of nutrient-rich foods that an individual eats on a daily or periodic basis to meet their energy needs and maintain good health. A well-balanced diet typically includes a variety of fruits, vegetables, whole grains, lean proteins, and low-fat dairy products.

A diet may also be prescribed for therapeutic purposes, such as in the management of certain medical conditions like diabetes, hypertension, or obesity. In these cases, a healthcare professional may recommend specific restrictions or modifications to an individual's regular diet to help manage their condition and improve their overall health.

It is important to note that a healthy and balanced diet should be tailored to an individual's age, gender, body size, activity level, and any underlying medical conditions. Consulting with a healthcare professional, such as a registered dietitian or nutritionist, can help ensure that an individual's dietary needs are being met in a safe and effective way.

Fertilizers are substances that are added to soil to provide nutrients necessary for plant growth and development. They typically contain macronutrients such as nitrogen (N), phosphorus (P), and potassium (K) in forms that can be readily taken up by plants. These three nutrients are essential for photosynthesis, energy transfer, and the production of proteins, nucleic acids, and other vital plant compounds.

Fertilizers may also contain secondary nutrients like calcium (Ca), magnesium (Mg), and sulfur (S) as well as micronutrients such as iron (Fe), manganese (Mn), zinc (Zn), copper (Cu), boron (B), and molybdenum (Mo). These elements play crucial roles in various plant metabolic processes, including enzyme activation, chlorophyll synthesis, and hormone production.

Fertilizers can be organic or synthetic. Organic fertilizers include materials like compost, manure, bone meal, and blood meal, which release nutrients slowly over time as they decompose. Synthetic fertilizers, also known as inorganic or chemical fertilizers, are manufactured chemicals that contain precise amounts of specific nutrients. They can be quickly absorbed by plants but may pose environmental risks if not used properly.

Proper fertilization is essential for optimal plant growth and crop yield. However, overuse or improper application of fertilizers can lead to nutrient runoff, soil degradation, water pollution, and other negative environmental impacts. Therefore, it's crucial to follow recommended fertilizer application rates and practices based on the specific needs of the plants and local regulations.

In the context of medical definitions, 'carbon' is not typically used as a standalone term. Carbon is an element with the symbol C and atomic number 6, which is naturally abundant in the human body and the environment. It is a crucial component of all living organisms, forming the basis of organic compounds, such as proteins, carbohydrates, lipids, and nucleic acids (DNA and RNA).

Carbon forms strong covalent bonds with various elements, allowing for the creation of complex molecules that are essential to life. In this sense, carbon is a fundamental building block of life on Earth. However, it does not have a specific medical definition as an isolated term.

Biomass is defined in the medical field as a renewable energy source derived from organic materials, primarily plant matter, that can be burned or converted into fuel. This includes materials such as wood, agricultural waste, and even methane gas produced by landfills. Biomass is often used as a source of heat, electricity, or transportation fuels, and its use can help reduce greenhouse gas emissions and dependence on fossil fuels.

In the context of human health, biomass burning can have both positive and negative impacts. On one hand, biomass can provide a source of heat and energy for cooking and heating, which can improve living standards and reduce exposure to harmful pollutants from traditional cooking methods such as open fires. On the other hand, biomass burning can also produce air pollution, including particulate matter and toxic chemicals, that can have negative effects on respiratory health and contribute to climate change.

Therefore, while biomass has the potential to be a sustainable and low-carbon source of energy, it is important to consider the potential health and environmental impacts of its use and implement appropriate measures to minimize any negative effects.

Mass spectrometry (MS) is an analytical technique used to identify and quantify the chemical components of a mixture or compound. It works by ionizing the sample, generating charged molecules or fragments, and then measuring their mass-to-charge ratio in a vacuum. The resulting mass spectrum provides information about the molecular weight and structure of the analytes, allowing for identification and characterization.

In simpler terms, mass spectrometry is a method used to determine what chemicals are present in a sample and in what quantities, by converting the chemicals into ions, measuring their masses, and generating a spectrum that shows the relative abundances of each ion type.

Hypophosphatemia is a medical condition characterized by abnormally low levels of phosphate (phosphorus) in the blood, specifically below 2.5 mg/dL. Phosphate is an essential electrolyte that plays a crucial role in various bodily functions such as energy production, bone formation, and maintaining acid-base balance.

Hypophosphatemia can result from several factors, including malnutrition, vitamin D deficiency, alcoholism, hormonal imbalances, and certain medications. Symptoms of hypophosphatemia may include muscle weakness, fatigue, bone pain, confusion, and respiratory failure in severe cases. Treatment typically involves correcting the underlying cause and administering phosphate supplements to restore normal levels.

"Bone" is the hard, dense connective tissue that makes up the skeleton of vertebrate animals. It provides support and protection for the body's internal organs, and serves as a attachment site for muscles, tendons, and ligaments. Bone is composed of cells called osteoblasts and osteoclasts, which are responsible for bone formation and resorption, respectively, and an extracellular matrix made up of collagen fibers and mineral crystals.

Bones can be classified into two main types: compact bone and spongy bone. Compact bone is dense and hard, and makes up the outer layer of all bones and the shafts of long bones. Spongy bone is less dense and contains large spaces, and makes up the ends of long bones and the interior of flat and irregular bones.

The human body has 206 bones in total. They can be further classified into five categories based on their shape: long bones, short bones, flat bones, irregular bones, and sesamoid bones.

Indicator dilution techniques are a group of methods used in medicine and research to measure various physiological variables, such as cardiac output or cerebral blood flow. These techniques involve introducing a known quantity of an indicator substance (like a dye or a radioactive tracer) into the system being studied and then measuring its concentration over time at a specific location downstream.

The basic principle behind these techniques is that the concentration of the indicator substance will be inversely proportional to the flow rate of the fluid through which it is moving. By measuring the concentration of the indicator substance at different points in time, researchers can calculate the flow rate using mathematical formulas.

Indicator dilution techniques are widely used in clinical and research settings because they are relatively non-invasive and can provide accurate and reliable measurements of various physiological variables. Some common examples of indicator dilution techniques include thermodilution, dye dilution, and Fick principle-based methods.

In the context of medicine and pharmacology, "kinetics" refers to the study of how a drug moves throughout the body, including its absorption, distribution, metabolism, and excretion (often abbreviated as ADME). This field is called "pharmacokinetics."

1. Absorption: This is the process of a drug moving from its site of administration into the bloodstream. Factors such as the route of administration (e.g., oral, intravenous, etc.), formulation, and individual physiological differences can affect absorption.

2. Distribution: Once a drug is in the bloodstream, it gets distributed throughout the body to various tissues and organs. This process is influenced by factors like blood flow, protein binding, and lipid solubility of the drug.

3. Metabolism: Drugs are often chemically modified in the body, typically in the liver, through processes known as metabolism. These changes can lead to the formation of active or inactive metabolites, which may then be further distributed, excreted, or undergo additional metabolic transformations.

4. Excretion: This is the process by which drugs and their metabolites are eliminated from the body, primarily through the kidneys (urine) and the liver (bile).

Understanding the kinetics of a drug is crucial for determining its optimal dosing regimen, potential interactions with other medications or foods, and any necessary adjustments for special populations like pediatric or geriatric patients, or those with impaired renal or hepatic function.

I'm sorry for any confusion, but "geologic sediments" is not a term used in medical definitions. Geological sediments are deposits of material that accumulate over time, usually in layers, as a result of natural geological processes such as weathering, erosion, and deposition. These sediments can eventually become rock formations and provide important clues about the Earth's history, including information about past climates, environments, and life on Earth.

In medicine, "absorption" refers to the process by which substances, including nutrients, medications, or toxins, are taken up and assimilated into the body's tissues or bloodstream after they have been introduced into the body via various routes (such as oral, intravenous, or transdermal).

The absorption of a substance depends on several factors, including its chemical properties, the route of administration, and the presence of other substances that may affect its uptake. For example, some medications may be better absorbed when taken with food, while others may require an empty stomach for optimal absorption.

Once a substance is absorbed into the bloodstream, it can then be distributed to various tissues throughout the body, where it may exert its effects or be metabolized and eliminated by the body's detoxification systems. Understanding the process of absorption is crucial in developing effective medical treatments and determining appropriate dosages for medications.

A plant root is not a medical term per se, but it is a term from botany, which is the study of plants. However, I can certainly provide a definition for you.

Plant roots are the underground organs of a plant that typically grow downward into the soil. They serve several important functions, including:

1. Anchorage: Roots help to stabilize the plant and keep it upright in the ground.
2. Absorption: Roots absorb water and nutrients from the soil, which are essential for the plant's growth and development.
3. Conduction: Roots conduct water and nutrients up to the above-ground parts of the plant, such as the stem and leaves.
4. Vegetative reproduction: Some plants can reproduce vegetatively through their roots, producing new plants from root fragments or specialized structures called rhizomes or tubers.

Roots are composed of several different tissues, including the epidermis, cortex, endodermis, and vascular tissue. The epidermis is the outermost layer of the root, which secretes a waxy substance called suberin that helps to prevent water loss. The cortex is the middle layer of the root, which contains cells that store carbohydrates and other nutrients. The endodermis is a thin layer of cells that surrounds the vascular tissue and regulates the movement of water and solutes into and out of the root. The vascular tissue consists of xylem and phloem, which transport water and nutrients throughout the plant.

Calcitriol is the active form of vitamin D, also known as 1,25-dihydroxyvitamin D. It is a steroid hormone that plays a crucial role in regulating calcium and phosphate levels in the body to maintain healthy bones. Calcitriol is produced in the kidneys from its precursor, calcidiol (25-hydroxyvitamin D), which is derived from dietary sources or synthesized in the skin upon exposure to sunlight.

Calcitriol promotes calcium absorption in the intestines, helps regulate calcium and phosphate levels in the kidneys, and stimulates bone cells (osteoblasts) to form new bone tissue while inhibiting the activity of osteoclasts, which resorb bone. This hormone is essential for normal bone mineralization and growth, as well as for preventing hypocalcemia (low calcium levels).

In addition to its role in bone health, calcitriol has various other physiological functions, including modulating immune responses, cell proliferation, differentiation, and apoptosis. Calcitriol deficiency or resistance can lead to conditions such as rickets in children and osteomalacia or osteoporosis in adults.

Magnesium is an essential mineral that plays a crucial role in various biological processes in the human body. It is the fourth most abundant cation in the body and is involved in over 300 enzymatic reactions, including protein synthesis, muscle and nerve function, blood glucose control, and blood pressure regulation. Magnesium also contributes to the structural development of bones and teeth.

In medical terms, magnesium deficiency can lead to several health issues, such as muscle cramps, weakness, heart arrhythmias, and seizures. On the other hand, excessive magnesium levels can cause symptoms like diarrhea, nausea, and muscle weakness. Magnesium supplements or magnesium-rich foods are often recommended to maintain optimal magnesium levels in the body.

Some common dietary sources of magnesium include leafy green vegetables, nuts, seeds, legumes, whole grains, and dairy products. Magnesium is also available in various forms as a dietary supplement, including magnesium oxide, magnesium citrate, magnesium chloride, and magnesium glycinate.

I'm sorry for any confusion, but "Phosphites" is not a term commonly used in medical definitions. It is a term more frequently used in chemistry and biochemistry, where it refers to salts or esters of phosphorous acid in which the phosphorus has an oxidation state of +3. If you're looking for information on a medical topic, could you please provide more context or clarify what you're asking? I'm here to help!

Animal feed refers to any substance or mixture of substances, whether processed, unprocessed, or partially processed, which is intended to be used as food for animals, including fish, without further processing. It includes ingredients such as grains, hay, straw, oilseed meals, and by-products from the milling, processing, and manufacturing industries. Animal feed can be in the form of pellets, crumbles, mash, or other forms, and is used to provide nutrients such as energy, protein, fiber, vitamins, and minerals to support the growth, reproduction, and maintenance of animals. It's important to note that animal feed must be safe, nutritious, and properly labeled to ensure the health and well-being of the animals that consume it.

Nephrocalcinosis is a medical condition characterized by the deposition of calcium salts in the renal parenchyma, specifically within the tubular epithelial cells and interstitium of the kidneys. This process can lead to chronic inflammation, tissue damage, and ultimately impaired renal function if left untreated.

The condition is often associated with metabolic disorders such as hyperparathyroidism, distal renal tubular acidosis, or hyperoxaluria; medications like loop diuretics, corticosteroids, or calcineurin inhibitors; and chronic kidney diseases. The diagnosis of nephrocalcinosis is typically made through imaging studies such as ultrasound, CT scan, or X-ray. Treatment usually involves addressing the underlying cause, modifying dietary habits, and administering medications to control calcium levels in the body.

Secondary hyperparathyroidism is a condition characterized by an overproduction of parathyroid hormone (PTH) from the parathyroid glands due to hypocalcemia (low levels of calcium in the blood). This condition is usually a result of chronic kidney disease, where the kidneys fail to convert vitamin D into its active form, leading to decreased absorption of calcium in the intestines. The body responds by increasing PTH production to maintain normal calcium levels, but over time, this results in high PTH levels and associated complications such as bone disease, kidney stones, and cardiovascular calcification.

Alkaline phosphatase (ALP) is an enzyme found in various body tissues, including the liver, bile ducts, digestive system, bones, and kidneys. It plays a role in breaking down proteins and minerals, such as phosphate, in the body.

The medical definition of alkaline phosphatase refers to its function as a hydrolase enzyme that removes phosphate groups from molecules at an alkaline pH level. In clinical settings, ALP is often measured through blood tests as a biomarker for various health conditions.

Elevated levels of ALP in the blood may indicate liver or bone diseases, such as hepatitis, cirrhosis, bone fractures, or cancer. Therefore, physicians may order an alkaline phosphatase test to help diagnose and monitor these conditions. However, it is essential to interpret ALP results in conjunction with other diagnostic tests and clinical findings for accurate diagnosis and treatment.

Electron Probe Microanalysis (EPMA) is a technique used in materials science and geology to analyze the chemical composition of materials at very small scales, typically on the order of microns or less. In this technique, a focused beam of electrons is directed at a sample, causing the emission of X-rays that are characteristic of the elements present in the sample. By analyzing the energy and intensity of these X-rays, researchers can determine the concentration of different elements in the sample with high precision and accuracy.

EPMA is typically performed using a specialized instrument called an electron probe microanalyzer (EPMA), which consists of an electron column for generating and focusing the electron beam, an X-ray spectrometer for analyzing the emitted X-rays, and a stage for positioning and manipulating the sample. The technique is widely used in fields such as mineralogy, geochemistry, metallurgy, and materials science to study the composition and structure of minerals, alloys, semiconductors, and other materials.

One of the key advantages of EPMA is its ability to analyze the chemical composition of small regions within a sample, even in cases where there are spatial variations in composition or where the sample is heterogeneous. This makes it an ideal technique for studying the distribution and behavior of trace elements in minerals, the microstructure of alloys and other materials, and the composition of individual grains or phases within a polyphase material. Additionally, EPMA can be used to analyze both conductive and non-conductive samples, making it a versatile tool for a wide range of applications.

Polyphosphates are compounds consisting of many phosphate groups linked together in the form of chains or rings. They are often used in various medical and healthcare applications, such as:

* Dental care products: Polyphosphates can help prevent the formation of dental plaque and calculus by binding to calcium ions in saliva and inhibiting the growth of bacteria that cause tooth decay.
* Nutritional supplements: Polyphosphates are sometimes used as a source of phosphorus in nutritional supplements, particularly for people who have kidney disease or other medical conditions that require them to limit their intake of phosphorus from food sources.
* Medical devices: Polyphosphates may be used in the manufacture of medical devices, such as contact lenses and catheters, to improve their biocompatibility and resistance to bacterial growth.

It's worth noting that while polyphosphates have various medical uses, they can also be found in many non-medical products, such as food additives, water treatment chemicals, and cleaning agents.

Intestinal absorption refers to the process by which the small intestine absorbs water, nutrients, and electrolytes from food into the bloodstream. This is a critical part of the digestive process, allowing the body to utilize the nutrients it needs and eliminate waste products. The inner wall of the small intestine contains tiny finger-like projections called villi, which increase the surface area for absorption. Nutrients are absorbed into the bloodstream through the walls of the capillaries in these villi, and then transported to other parts of the body for use or storage.

Sewage is not typically considered a medical term, but it does have relevance to public health and medicine. Sewage is the wastewater that is produced by households and industries, which contains a variety of contaminants including human waste, chemicals, and other pollutants. It can contain various pathogens such as bacteria, viruses, and parasites, which can cause diseases in humans if they come into contact with it or consume contaminated food or water. Therefore, the proper treatment and disposal of sewage is essential to prevent the spread of infectious diseases and protect public health.

Rickets is a medical condition characterized by the softening and weakening of bones in children, primarily caused by deficiency of vitamin D, calcium, or phosphate. It leads to skeletal deformities, bone pain, and growth retardation. Prolonged lack of sunlight exposure, inadequate intake of vitamin D-rich foods, or impaired absorption or utilization of vitamin D can contribute to the development of rickets.

Gas Chromatography-Mass Spectrometry (GC-MS) is a powerful analytical technique that combines the separating power of gas chromatography with the identification capabilities of mass spectrometry. This method is used to separate, identify, and quantify different components in complex mixtures.

In GC-MS, the mixture is first vaporized and carried through a long, narrow column by an inert gas (carrier gas). The various components in the mixture interact differently with the stationary phase inside the column, leading to their separation based on their partition coefficients between the mobile and stationary phases. As each component elutes from the column, it is then introduced into the mass spectrometer for analysis.

The mass spectrometer ionizes the sample, breaks it down into smaller fragments, and measures the mass-to-charge ratio of these fragments. This information is used to generate a mass spectrum, which serves as a unique "fingerprint" for each compound. By comparing the generated mass spectra with reference libraries or known standards, analysts can identify and quantify the components present in the original mixture.

GC-MS has wide applications in various fields such as forensics, environmental analysis, drug testing, and research laboratories due to its high sensitivity, specificity, and ability to analyze volatile and semi-volatile compounds.

Phosphorus radioisotopes are radioactive isotopes or variants of the element phosphorus that emit radiation. Phosphorus has several radioisotopes, with the most common ones being phosphorus-32 (^32P) and phosphorus-33 (^33P). These radioisotopes are used in various medical applications such as cancer treatment and diagnostic procedures.

Phosphorus-32 has a half-life of approximately 14.3 days and emits beta particles, making it useful for treating certain types of cancer, such as leukemia and lymphoma. It can also be used in brachytherapy, a type of radiation therapy that involves placing a radioactive source close to the tumor.

Phosphorus-33 has a shorter half-life of approximately 25.4 days and emits both beta particles and gamma rays. This makes it useful for diagnostic procedures, such as positron emission tomography (PET) scans, where the gamma rays can be detected and used to create images of the body's internal structures.

It is important to note that handling and using radioisotopes requires specialized training and equipment to ensure safety and prevent radiation exposure.

Food additives are substances that are added to food or drink during manufacturing or processing to perform various functions such as preservation, coloring, flavoring, enhancing taste and texture, and increasing nutritional value. These additives can be natural or synthetic and must be approved by regulatory authorities before they can be used in food products. Examples of food additives include salt, sugar, vinegar, spices, artificial flavors, preservatives, emulsifiers, and food dyes. It is important to note that some people may have allergies or sensitivities to certain food additives, and excessive consumption of some additives may have negative health effects.

Renal dialysis is a medical procedure that is used to artificially remove waste products, toxins, and excess fluids from the blood when the kidneys are no longer able to perform these functions effectively. This process is also known as hemodialysis.

During renal dialysis, the patient's blood is circulated through a special machine called a dialyzer or an artificial kidney, which contains a semi-permeable membrane that filters out waste products and excess fluids from the blood. The cleaned blood is then returned to the patient's body.

Renal dialysis is typically recommended for patients with advanced kidney disease or kidney failure, such as those with end-stage renal disease (ESRD). It is a life-sustaining treatment that helps to maintain the balance of fluids and electrolytes in the body, prevent the buildup of waste products and toxins, and control blood pressure.

There are two main types of renal dialysis: hemodialysis and peritoneal dialysis. Hemodialysis is the most common type and involves using a dialyzer to filter the blood outside the body. Peritoneal dialysis, on the other hand, involves placing a catheter in the abdomen and using the lining of the abdomen (peritoneum) as a natural filter to remove waste products and excess fluids from the body.

Overall, renal dialysis is an essential treatment option for patients with kidney failure, helping them to maintain their quality of life and prolong their survival.

Chronic kidney failure, also known as chronic kidney disease (CKD) stage 5 or end-stage renal disease (ESRD), is a permanent loss of kidney function that occurs gradually over a period of months to years. It is defined as a glomerular filtration rate (GFR) of less than 15 ml/min, which means the kidneys are filtering waste and excess fluids at less than 15% of their normal capacity.

CKD can be caused by various underlying conditions such as diabetes, hypertension, glomerulonephritis, polycystic kidney disease, and recurrent kidney infections. Over time, the damage to the kidneys can lead to a buildup of waste products and fluids in the body, which can cause a range of symptoms including fatigue, weakness, shortness of breath, nausea, vomiting, and confusion.

Treatment for chronic kidney failure typically involves managing the underlying condition, making lifestyle changes such as following a healthy diet, and receiving supportive care such as dialysis or a kidney transplant to replace lost kidney function.

Hydrogen-ion concentration, also known as pH, is a measure of the acidity or basicity of a solution. It is defined as the negative logarithm (to the base 10) of the hydrogen ion activity in a solution. The standard unit of measurement is the pH unit. A pH of 7 is neutral, less than 7 is acidic, and greater than 7 is basic.

In medical terms, hydrogen-ion concentration is important for maintaining homeostasis within the body. For example, in the stomach, a high hydrogen-ion concentration (low pH) is necessary for the digestion of food. However, in other parts of the body such as blood, a high hydrogen-ion concentration can be harmful and lead to acidosis. Conversely, a low hydrogen-ion concentration (high pH) in the blood can lead to alkalosis. Both acidosis and alkalosis can have serious consequences on various organ systems if not corrected.

Calcium carbonate is a chemical compound with the formula CaCO3. It is a common substance found in rocks and in the shells of many marine animals. As a mineral, it is known as calcite or aragonite.

In the medical field, calcium carbonate is often used as a dietary supplement to prevent or treat calcium deficiency. It is also commonly used as an antacid to neutralize stomach acid and relieve symptoms of heartburn, acid reflux, and indigestion.

Calcium carbonate works by reacting with hydrochloric acid in the stomach to form water, carbon dioxide, and calcium chloride. This reaction helps to raise the pH level in the stomach and neutralize excess acid.

It is important to note that excessive use of calcium carbonate can lead to hypercalcemia, a condition characterized by high levels of calcium in the blood, which can cause symptoms such as nausea, vomiting, constipation, confusion, and muscle weakness. Therefore, it is recommended to consult with a healthcare provider before starting any new supplement regimen.

An "ecosystem" is not a term that has a specific medical definition, as it is a concept that is more commonly used in the fields of ecology and environmental science. However, I can provide you with the general ecological definition of an ecosystem:

An ecosystem is a community of living organisms interacting with each other and their non-living environment, including both biotic factors (plants, animals, microorganisms) and abiotic factors (climate, soil, water, and air). These interactions create a complex network of relationships that form the foundation of ecological processes, such as energy flow, nutrient cycling, and population dynamics.

While there is no direct medical definition for an ecosystem, understanding the principles of ecosystems can have important implications for human health. For example, healthy ecosystems can provide clean air and water, regulate climate, support food production, and offer opportunities for recreation and relaxation, all of which contribute to overall well-being. Conversely, degraded ecosystems can lead to increased exposure to environmental hazards, reduced access to natural resources, and heightened risks of infectious diseases. Therefore, maintaining the health and integrity of ecosystems is crucial for promoting human health and preventing disease.

I'm sorry for any confusion, but "Fresh Water" is not a medical term. It is a term used to describe water that contains low concentrations of dissolved salts and other dissolved minerals. It is distinguished from saline water, which includes saltwater found in the ocean and brackish water found in estuaries. Fresh water is essential for many biological processes and is the primary source of water for human consumption, agriculture, and industrial use.

In the context of medicine, the term "elements" generally refers to the basic constituents or parts that make up a whole. These can include chemical elements, such as carbon, hydrogen, and oxygen, which are the building blocks of biological molecules like proteins, lipids, and carbohydrates.

However, "elements" can also refer more broadly to the fundamental components of a system or process. For example, in traditional humorism, one of the ancient medical systems, the four "elements" were considered to be black bile, yellow bile, phlegm, and blood, which were believed to correspond to different temperaments and bodily functions.

In modern medicine, the term is less commonly used, but it may still refer to the basic components of a biological or chemical system, such as the elements of a chemical reaction or the building blocks of a cell.

Mercury isotopes refer to variants of the chemical element mercury (Hg) that have different numbers of neutrons in their atomic nuclei. This means that while all mercury isotopes have 80 protons in their nucleus, they can have different numbers of neutrons, ranging from 120 to 124 or more.

The most common and stable mercury isotope is Hg-202, which has 80 protons and 122 neutrons. However, there are several other mercury isotopes that occur naturally in trace amounts, including Hg-196, Hg-198, Hg-199, Hg-200, and Hg-204.

Mercury isotopes can also be produced artificially through various nuclear reactions. These isotopes may have different physical and chemical properties than the more common mercury isotopes, which can make them useful for a variety of applications, such as in medical imaging or environmental monitoring. However, some mercury isotopes are radioactive and can be hazardous to handle or dispose of improperly.

"Manure" is not a term typically used in medical definitions. However, it is commonly referred to in agriculture and horticulture. Manure is defined as organic matter, such as animal feces and urine, that is used as a fertilizer to enrich and amend the soil. It is often rich in nutrients like nitrogen, phosphorus, and potassium, which are essential for plant growth. While manure can be beneficial for agriculture and gardening, it can also pose risks to human health if not handled properly due to the potential presence of pathogens and other harmful substances.

Halomonadaceae is a family of halophilic (salt-loving) bacteria within the order Oceanospirillales. These bacteria are commonly found in saline environments such as salt lakes, marine solar salterns, and salted foods. They have the ability to grow in media with a wide range of salinities, from around 0.5% to saturated salt concentrations. Some members of this family can also tolerate or even require the presence of organic solvents. The type genus of Halomonadaceae is Halomonas.

The chemical element aluminum (or aluminium in British English) is a silvery-white, soft, non-magnetic, ductile metal. The atomic number of aluminum is 13 and its symbol on the periodic table is Al. It is the most abundant metallic element in the Earth's crust and is found in a variety of minerals such as bauxite.

Aluminum is resistant to corrosion due to the formation of a thin layer of aluminum oxide on its surface that protects it from further oxidation. It is lightweight, has good thermal and electrical conductivity, and can be easily formed and machined. These properties make aluminum a widely used metal in various industries such as construction, packaging, transportation, and electronics.

In the medical field, aluminum is used in some medications and medical devices. For example, aluminum hydroxide is commonly used as an antacid to neutralize stomach acid and treat heartburn, while aluminum salts are used as adjuvants in vaccines to enhance the immune response. However, excessive exposure to aluminum can be harmful and has been linked to neurological disorders such as Alzheimer's disease, although the exact relationship between aluminum and these conditions is not fully understood.

A medical definition for "plant shoots" may not be readily available, as the term is primarily used in botany and horticulture. However, I can provide you with a general definition:

Plant shoots refer to the above-ground portion of a plant, which typically includes structures like stems, leaves, flowers, and buds. Shoots originate from the seed or the growing tip of the plant and are responsible for photosynthesis, nutrient absorption, and reproduction. In some contexts, "plant shoots" might also refer to new growth that emerges from an existing plant, such as when a leaf or stem sprouts a new branch or flower.

Feces are the solid or semisolid remains of food that could not be digested or absorbed in the small intestine, along with bacteria and other waste products. After being stored in the colon, feces are eliminated from the body through the rectum and anus during defecation. Feces can vary in color, consistency, and odor depending on a person's diet, health status, and other factors.

The parathyroid glands are four small endocrine glands located in the neck, usually near or behind the thyroid gland. They secrete parathyroid hormone (PTH), which plays a critical role in regulating calcium and phosphate levels in the blood and bones. PTH helps maintain the balance of these minerals by increasing the absorption of calcium from food in the intestines, promoting reabsorption of calcium in the kidneys, and stimulating the release of calcium from bones when needed. Additionally, PTH decreases the excretion of calcium through urine and reduces phosphate reabsorption in the kidneys, leading to increased phosphate excretion. Disorders of the parathyroid glands can result in conditions such as hyperparathyroidism (overactive glands) or hypoparathyroidism (underactive glands), which can have significant impacts on calcium and phosphate homeostasis and overall health.

Phosphocreatine (PCr) is a high-energy phosphate compound found in the skeletal muscles, cardiac muscle, and brain. It plays a crucial role in energy metabolism and storage within cells. Phosphocreatine serves as an immediate energy reserve that helps regenerate ATP (adenosine triphosphate), the primary source of cellular energy, during short bursts of intense activity or stress. This process is facilitated by the enzyme creatine kinase, which catalyzes the transfer of a phosphate group from phosphocreatine to ADP (adenosine diphosphate) to form ATP.

In a medical context, phosphocreatine levels may be assessed in muscle biopsies or magnetic resonance spectroscopy (MRS) imaging to evaluate muscle energy metabolism and potential mitochondrial dysfunction in conditions such as muscular dystrophies, mitochondrial disorders, and neuromuscular diseases. Additionally, phosphocreatine depletion has been implicated in various pathological processes, including ischemia-reperfusion injury, neurodegenerative disorders, and heart failure.

Chronic Renal Insufficiency (CRI) is a medical condition characterized by a gradual and progressive loss of kidney function over a period of months or years. It is also known as Chronic Kidney Disease (CKD). The main function of the kidneys is to filter waste products and excess fluids from the blood, which are then excreted in the urine. When the kidneys become insufficient, these waste products and fluids accumulate in the body, leading to various complications.

CRI is defined as a glomerular filtration rate (GFR) of less than 60 ml/min/1.73m2 for three months or more, regardless of cause. GFR is a measure of kidney function that estimates how well the kidneys are filtering waste products from the blood. The condition is classified into five stages based on the severity of the disease and the GFR value.

Stage 1: GFR greater than or equal to 90 ml/min/1.73m2
Stage 2: GFR between 60-89 ml/min/1.73m2
Stage 3: GFR between 30-59 ml/min/1.73m2
Stage 4: GFR between 15-29 ml/min/1.73m2
Stage 5: GFR less than 15 ml/min/1.73m2 or dialysis

CRI can be caused by various underlying conditions such as diabetes, hypertension, glomerulonephritis, polycystic kidney disease, and other genetic or acquired disorders. Symptoms of CRI may include fatigue, weakness, loss of appetite, swelling in the legs and ankles, shortness of breath, and changes in urination patterns. Treatment for CRI focuses on slowing down the progression of the disease, managing symptoms, and preventing complications. This may involve lifestyle modifications, medication, dialysis, or kidney transplantation.

Renal osteodystrophy is a bone disease that occurs in individuals with chronic kidney disease (CKD). It is characterized by abnormalities in the bones' structure and mineral composition due to disturbances in the metabolism of calcium, phosphorus, and vitamin D. These metabolic disturbances result from the kidneys' decreased ability to maintain balance in the levels of these minerals and hormones.

Renal osteodystrophy can manifest as several bone disorders, including:

1. Osteitis fibrosa cystica: Increased bone turnover due to excessive parathyroid hormone (PTH) production, leading to high levels of alkaline phosphatase and increased resorption of bones.
2. Adynamic bone disease: Decreased bone turnover due to reduced PTH levels, resulting in low bone formation rates and increased fracture risk.
3. Mixed uremic osteodystrophy: A combination of high and low bone turnover, with varying degrees of mineralization defects.
4. Osteomalacia: Defective mineralization of bones due to vitamin D deficiency or resistance, leading to soft and weak bones.

Symptoms of renal osteodystrophy may include bone pain, muscle weakness, fractures, deformities, and growth retardation in children. Diagnosis typically involves laboratory tests, imaging studies, and sometimes bone biopsies. Treatment focuses on correcting the metabolic imbalances through dietary modifications, medications (such as phosphate binders, vitamin D analogs, and calcimimetics), and addressing any secondary hyperparathyroidism if present.

I'm sorry for any confusion, but the term "food chain" is not typically used in a medical context. It is a concept from ecology that describes the sequence of organisms through which food and energy pass as one organism eats another.

However, if you're referring to "food web" or "dietary intake," these terms might be more applicable in a medical context. For instance, dietary intake refers to what and how much a person consumes, which can have significant implications for their health. A food web, on the other hand, is a more complex network of relationships between different species that consume and are consumed by others, which can help researchers understand the impacts of changes in one species' population or behavior on others within an ecosystem.

If you meant to ask about something else, please provide more context or clarify your question, and I will do my best to provide a helpful answer!

Vitamin D is a fat-soluble secosteroid that is crucial for the regulation of calcium and phosphate levels in the body, which are essential for maintaining healthy bones and teeth. It can be synthesized by the human body when skin is exposed to ultraviolet-B (UVB) rays from sunlight, or it can be obtained through dietary sources such as fatty fish, fortified dairy products, and supplements. There are two major forms of vitamin D: vitamin D2 (ergocalciferol), which is found in some plants and fungi, and vitamin D3 (cholecalciferol), which is produced in the skin or obtained from animal-derived foods. Both forms need to undergo two hydroxylations in the body to become biologically active as calcitriol (1,25-dihydroxyvitamin D3), the hormonally active form of vitamin D. This activated form exerts its effects by binding to the vitamin D receptor (VDR) found in various tissues, including the small intestine, bone, kidney, and immune cells, thereby influencing numerous physiological processes such as calcium homeostasis, bone metabolism, cell growth, and immune function.

I'm sorry for any confusion, but "Hydrogen" is not a medical term. It is a chemical element with the symbol H and atomic number 1. It is the lightest and most abundant chemical element in the universe, making up about 75% of its elemental mass.

In a medical context, hydrogen can be discussed in terms of molecular hydrogen (H2) which has been studied for potential therapeutic benefits. Some research explores its use as an antioxidant and anti-inflammatory agent, but more studies are needed to confirm these effects and understand the mechanisms behind them.

Organophosphorus compounds are a class of chemical substances that contain phosphorus bonded to organic compounds. They are used in various applications, including as plasticizers, flame retardants, pesticides (insecticides, herbicides, and nerve gases), and solvents. In medicine, they are also used in the treatment of certain conditions such as glaucoma. However, organophosphorus compounds can be toxic to humans and animals, particularly those that affect the nervous system by inhibiting acetylcholinesterase, an enzyme that breaks down the neurotransmitter acetylcholine. Exposure to these compounds can cause symptoms such as nausea, vomiting, muscle weakness, and in severe cases, respiratory failure and death.

Phytoplankton are microscopic photosynthetic organisms that live in watery environments such as oceans, seas, lakes, and rivers. They are a diverse group of organisms, including bacteria, algae, and protozoa. Phytoplankton are a critical component of the marine food chain, serving as primary producers that convert sunlight, carbon dioxide, and nutrients into organic matter through photosynthesis. This organic matter forms the base of the food chain and supports the growth and survival of many larger organisms, including zooplankton, fish, and other marine animals. Phytoplankton also play an important role in global carbon cycling and help to regulate Earth's climate by absorbing carbon dioxide from the atmosphere and releasing oxygen.

Fluid waste disposal in a medical context refers to the proper and safe management of liquid byproducts generated during medical procedures, patient care, or research. These fluids can include bodily excretions (such as urine, feces, or vomit), irrigation solutions, blood, or other biological fluids.

The process of fluid waste disposal involves several steps:

1. Collection: Fluid waste is collected in appropriate containers that are designed to prevent leakage and contamination.
2. Segregation: Different types of fluid waste may require separate collection and disposal methods based on their infectious or hazardous nature.
3. Treatment: Depending on the type and volume of fluid waste, various treatments can be applied, such as disinfection, sterilization, or chemical neutralization, to reduce the risk of infection or harm to the environment and personnel.
4. Disposal: Treated fluid waste is then disposed of according to local regulations, which may involve transporting it to a designated waste management facility for further processing or disposal in a safe and environmentally friendly manner (e.g., deep well injection, incineration, or landfilling).
5. Documentation and tracking: Proper records should be maintained to ensure compliance with regulatory requirements and to enable effective monitoring and auditing of the waste disposal process.

It is essential to handle fluid waste disposal carefully to minimize the risk of infection, protect the environment, and maintain regulatory compliance. Healthcare facilities must adhere to strict guidelines and regulations regarding fluid waste management to ensure the safety of patients, staff, and the community.

I'm sorry for any confusion, but "soybeans" are not a medical term. They are a type of legume that is commonly used in agriculture and food production. The medical community might discuss soybeans in the context of nutrition or allergies, but there isn't a formal medical definition for this term.

Here's some general information: Soybeans, scientifically known as Glycine max, are native to East Asia and are now grown worldwide. They are a significant source of plant-based protein and oil. Soybeans contain various nutrients, including essential amino acids, fiber, B vitamins, and minerals like calcium, iron, magnesium, and zinc. They are used in various food products such as tofu, soy milk, tempeh, and miso. Additionally, soybeans are also used in the production of industrial products, including biodiesel, plastics, and inks. Some people may have allergic reactions to soybeans or soy products.

The metacarpus is the medical term for the part of the hand located between the carpus (wrist) and the digits (fingers). It consists of five bones, known as the metacarpal bones, which are numbered 1 to 5 from the thumb side to the little finger side. Each metacarpal bone has a base, a shaft, and a head. The bases of the metacarpal bones articulate with the carpal bones to form the wrist joint, while the heads of the metacarpal bones form the knuckles at the back of the hand.

The metacarpus plays an essential role in hand function as it provides stability and support for the movement of the fingers and thumb. Injuries or conditions affecting the metacarpus can significantly impact hand function, causing pain, stiffness, weakness, or deformity.

"Lupinus" is not a medical term. It is the genus name for the group of plants commonly known as lupines or bluebonnets. Some people may use "lupinus" in a medical context to refer to an allergy or sensitivity to lupine beans or other parts of the lupine plant, which can cause symptoms such as rash, itching, and digestive issues. However, this is not a widely recognized medical condition and reactions to lupines are relatively rare. If you have any concerns about a potential allergy or sensitivity to lupines, it is best to consult with a healthcare professional for proper evaluation and treatment.

Deuterium oxide, also known as heavy water, is a compound consisting of two atoms of deuterium (a heavy isotope of hydrogen) and one atom of oxygen. Its chemical formula is D2O. Deuterium oxide has physical and chemical properties similar to those of regular water (H2O), but its density and boiling point are slightly higher due to the increased atomic weight. It is used in various scientific research applications, including as a tracer in biochemical and medical studies.

Planetary evolution is a field of study that focuses on the processes that have shaped the formation, development, and changes of planets and other celestial bodies over time. This encompasses various scientific disciplines, including astronomy, astrobiology, geology, and atmospheric science. The study of planetary evolution helps scientists understand how planets form, how they change over time, and the conditions that allow for the development of life.

The process of planetary evolution can be driven by a variety of factors, including:

1. Formation: Planets form from a protoplanetary disk, a rotating disk of gas and dust surrounding a young star. Over time, solid particles in the disk collide and stick together to form larger and larger bodies, eventually leading to the formation of planets.
2. Internal differentiation: As planets grow, their interiors differentiate into layers based on density, with heavier materials sinking towards the center and lighter materials rising towards the surface. This process can lead to the formation of a core, mantle, and crust.
3. Geological activity: Planetary evolution is also influenced by geological processes such as volcanism, tectonics, and erosion. These processes can shape the planet's surface, create mountain ranges, and carve out valleys and basins.
4. Atmospheric evolution: The evolution of a planet's atmosphere is closely tied to its geological activity and the presence of volatiles (gases that easily vaporize). Over time, the composition of a planet's atmosphere can change due to processes such as outgassing from the interior, chemical reactions, and interactions with the solar wind.
5. Climate evolution: The climate of a planet can also evolve over time due to changes in its orbit, axial tilt, and atmospheric composition. These factors can influence the amount of sunlight a planet receives and the greenhouse effect, which can lead to global warming or cooling.
6. Impact events: Collisions with other celestial bodies, such as asteroids and comets, can significantly impact a planet's evolution by causing large-scale changes to its surface and atmosphere.
7. Life: On planets where life emerges, biological processes can also play a role in shaping the planet's environment and influencing its evolution. For example, photosynthetic organisms can produce oxygen, which can alter the composition of a planet's atmosphere.

Understanding the various factors that contribute to a planet's evolution is crucial for understanding the formation and development of planetary systems and searching for potentially habitable exoplanets.

"Animal nutritional physiological phenomena" is not a standardized medical or scientific term. However, it seems to refer to the processes and functions related to nutrition and physiology in animals. Here's a breakdown of the possible components:

1. Animal: This term refers to non-human living organisms that are multicellular, heterotrophic, and have a distinct nervous system.
2. Nutritional: This term pertains to the nourishment and energy requirements of an animal, including the ingestion, digestion, absorption, transportation, metabolism, and excretion of nutrients.
3. Physiological: This term refers to the functions and processes that occur within a living organism, including the interactions between different organs and systems.
4. Phenomena: This term generally means an observable fact or event.

Therefore, "animal nutritional physiological phenomena" could refer to the observable events and processes related to nutrition and physiology in animals. Examples of such phenomena include digestion, absorption, metabolism, energy production, growth, reproduction, and waste elimination.

Zinc is an essential mineral that is vital for the functioning of over 300 enzymes and involved in various biological processes in the human body, including protein synthesis, DNA synthesis, immune function, wound healing, and cell division. It is a component of many proteins and participates in the maintenance of structural integrity and functionality of proteins. Zinc also plays a crucial role in maintaining the sense of taste and smell.

The recommended daily intake of zinc varies depending on age, sex, and life stage. Good dietary sources of zinc include red meat, poultry, seafood, beans, nuts, dairy products, and fortified cereals. Zinc deficiency can lead to various health problems, including impaired immune function, growth retardation, and developmental delays in children. On the other hand, excessive intake of zinc can also have adverse effects on health, such as nausea, vomiting, and impaired immune function.

"Swine" is a common term used to refer to even-toed ungulates of the family Suidae, including domestic pigs and wild boars. However, in a medical context, "swine" often appears in the phrase "swine flu," which is a strain of influenza virus that typically infects pigs but can also cause illness in humans. The 2009 H1N1 pandemic was caused by a new strain of swine-origin influenza A virus, which was commonly referred to as "swine flu." It's important to note that this virus is not transmitted through eating cooked pork products; it spreads from person to person, mainly through respiratory droplets produced when an infected person coughs or sneezes.

Mycorrhizae are symbiotic associations between fungi and the roots of most plant species. In a mycorrhizal association, fungi colonize the root tissues of plants and extend their mycelial networks into the surrounding soil. This association enhances the nutrient uptake capacity of the host plant, particularly with regards to phosphorus and nitrogen, while the fungi receive carbohydrates from the plant for their own growth and metabolism.

Mycorrhizal fungi can be broadly classified into two types: ectomycorrhizae and endomycorrhizae (or arbuscular mycorrhizae). Ectomycorrhizae form a sheath around the root surface, while endomycorrhizae penetrate the root cells and form structures called arbuscules, where nutrient exchange occurs. Mycorrhizal associations play crucial roles in maintaining ecosystem stability, promoting plant growth, and improving soil structure and fertility.

Dietary proteins are sources of protein that come from the foods we eat. Protein is an essential nutrient for the human body, required for various bodily functions such as growth, repair, and immune function. Dietary proteins are broken down into amino acids during digestion, which are then absorbed and used to synthesize new proteins in the body.

Dietary proteins can be classified as complete or incomplete based on their essential amino acid content. Complete proteins contain all nine essential amino acids that cannot be produced by the human body and must be obtained through the diet. Examples of complete protein sources include meat, poultry, fish, eggs, dairy products, soy, and quinoa.

Incomplete proteins lack one or more essential amino acids and are typically found in plant-based foods such as grains, legumes, nuts, and seeds. However, by combining different incomplete protein sources, it is possible to obtain all the essential amino acids needed for a complete protein diet. This concept is known as complementary proteins.

It's important to note that while dietary proteins are essential for good health, excessive protein intake can have negative effects on the body, such as increased stress on the kidneys and bones. Therefore, it's recommended to consume protein in moderation as part of a balanced and varied diet.

Hydroxycholecalciferols are metabolites of vitamin D that are formed in the liver and kidneys. They are important for maintaining calcium homeostasis in the body by promoting the absorption of calcium from the gut and reabsorption of calcium from the kidneys.

The two main forms of hydroxycholecalciferols are 25-hydroxyvitamin D (25(OH)D) and 1,25-dihydroxyvitamin D (1,25(OH)2D). 25-hydroxyvitamin D is the major circulating form of vitamin D in the body and is used as a clinical measure of vitamin D status. It is converted to 1,25-dihydroxyvitamin D in the kidneys by the enzyme 1α-hydroxylase, which is activated in response to low serum calcium or high phosphate levels.

1,25-dihydroxyvitamin D is the biologically active form of vitamin D and plays a critical role in regulating calcium homeostasis by increasing intestinal calcium absorption and promoting bone health. Deficiency in hydroxycholecalciferols can lead to rickets in children and osteomalacia or osteoporosis in adults, characterized by weakened bones and increased risk of fractures.

Calcium compounds are chemical substances that contain calcium ions (Ca2+) bonded to various anions. Calcium is an essential mineral for human health, and calcium compounds have numerous biological and industrial applications. Here are some examples of calcium compounds with their medical definitions:

1. Calcium carbonate (CaCO3): A common mineral found in rocks and sediments, calcium carbonate is also a major component of shells, pearls, and bones. It is used as a dietary supplement to prevent or treat calcium deficiency and as an antacid to neutralize stomach acid.
2. Calcium citrate (C6H8CaO7): A calcium salt of citric acid, calcium citrate is often used as a dietary supplement to prevent or treat calcium deficiency. It is more soluble in water and gastric juice than calcium carbonate, making it easier to absorb, especially for people with low stomach acid.
3. Calcium gluconate (C12H22CaO14): A calcium salt of gluconic acid, calcium gluconate is used as a medication to treat or prevent hypocalcemia (low blood calcium levels) and hyperkalemia (high blood potassium levels). It can be given intravenously, orally, or topically.
4. Calcium chloride (CaCl2): A white, deliquescent salt, calcium chloride is used as a de-icing agent, a food additive, and a desiccant. In medical settings, it can be used to treat hypocalcemia or hyperkalemia, or as an antidote for magnesium overdose.
5. Calcium lactate (C6H10CaO6): A calcium salt of lactic acid, calcium lactate is used as a dietary supplement to prevent or treat calcium deficiency. It is less commonly used than calcium carbonate or calcium citrate but may be better tolerated by some people.
6. Calcium phosphate (Ca3(PO4)2): A mineral found in rocks and bones, calcium phosphate is used as a dietary supplement to prevent or treat calcium deficiency. It can also be used as a food additive or a pharmaceutical excipient.
7. Calcium sulfate (CaSO4): A white, insoluble powder, calcium sulfate is used as a desiccant, a plaster, and a fertilizer. In medical settings, it can be used to treat hypocalcemia or as an antidote for magnesium overdose.
8. Calcium hydroxide (Ca(OH)2): A white, alkaline powder, calcium hydroxide is used as a disinfectant, a flocculant, and a building material. In medical settings, it can be used to treat hyperkalemia or as an antidote for aluminum overdose.
9. Calcium acetate (Ca(C2H3O2)2): A white, crystalline powder, calcium acetate is used as a food additive and a medication. It can be used to treat hyperphosphatemia (high blood phosphate levels) in patients with kidney disease.
10. Calcium carbonate (CaCO3): A white, chalky powder, calcium carbonate is used as a dietary supplement, a food additive, and a pharmaceutical excipient. It can also be used as a building material and a mineral supplement.

Water quality, in the context of public health and environmental medicine, refers to the chemical, physical, and biological characteristics of water that determine its suitability for various uses, such as drinking, recreation, or industrial processes. The term encompasses a wide range of parameters, including but not limited to:

1. Microbial contaminants: Presence of pathogenic bacteria, viruses, parasites, and other microorganisms that can cause waterborne diseases.
2. Chemical contaminants: Including heavy metals (e.g., lead, mercury), pesticides, volatile organic compounds (VOCs), disinfection byproducts, and other potentially harmful substances.
3. Physical parameters: Such as temperature, turbidity (cloudiness), color, taste, and odor, which can affect the water's acceptability for different uses.
4. Radiological contaminants: Exposure to ionizing radiation from radioactive elements present in water sources.

Regulatory agencies establish guidelines and standards for water quality to protect public health and minimize potential adverse effects associated with exposure to contaminated water. Regular monitoring, treatment, and management of water sources are essential to ensure safe and reliable water supplies.

Radioisotopes, also known as radioactive isotopes or radionuclides, are variants of chemical elements that have unstable nuclei and emit radiation in the form of alpha particles, beta particles, gamma rays, or conversion electrons. These isotopes are formed when an element's nucleus undergoes natural or artificial radioactive decay.

Radioisotopes can be produced through various processes, including nuclear fission, nuclear fusion, and particle bombardment in a cyclotron or other types of particle accelerators. They have a wide range of applications in medicine, industry, agriculture, research, and energy production. In the medical field, radioisotopes are used for diagnostic imaging, radiation therapy, and in the labeling of molecules for research purposes.

It is important to note that handling and using radioisotopes requires proper training, safety measures, and regulatory compliance due to their ionizing radiation properties, which can pose potential health risks if not handled correctly.

Ergocalciferols are a form of vitamin D, specifically vitamin D2, that is found in some plants. They are not produced by the human body and must be obtained through diet or supplementation. Ergocalciferols can be converted into an active form of vitamin D in the body, which is important for maintaining healthy bones and calcium levels. However, vitamin D3 (cholecalciferol), which is produced by the body in response to sunlight exposure, is generally considered to be more effective at raising and maintaining vitamin D levels in the body than ergocalciferols.

In the field of medicine, "time factors" refer to the duration of symptoms or time elapsed since the onset of a medical condition, which can have significant implications for diagnosis and treatment. Understanding time factors is crucial in determining the progression of a disease, evaluating the effectiveness of treatments, and making critical decisions regarding patient care.

For example, in stroke management, "time is brain," meaning that rapid intervention within a specific time frame (usually within 4.5 hours) is essential to administering tissue plasminogen activator (tPA), a clot-busting drug that can minimize brain damage and improve patient outcomes. Similarly, in trauma care, the "golden hour" concept emphasizes the importance of providing definitive care within the first 60 minutes after injury to increase survival rates and reduce morbidity.

Time factors also play a role in monitoring the progression of chronic conditions like diabetes or heart disease, where regular follow-ups and assessments help determine appropriate treatment adjustments and prevent complications. In infectious diseases, time factors are crucial for initiating antibiotic therapy and identifying potential outbreaks to control their spread.

Overall, "time factors" encompass the significance of recognizing and acting promptly in various medical scenarios to optimize patient outcomes and provide effective care.

I believe there may be a slight misunderstanding in your question. "Plant leaves" are not a medical term, but rather a general biological term referring to a specific organ found in plants.

Leaves are organs that are typically flat and broad, and they are the primary site of photosynthesis in most plants. They are usually green due to the presence of chlorophyll, which is essential for capturing sunlight and converting it into chemical energy through photosynthesis.

While leaves do not have a direct medical definition, understanding their structure and function can be important in various medical fields, such as pharmacognosy (the study of medicinal plants) or environmental health. For example, certain plant leaves may contain bioactive compounds that have therapeutic potential, while others may produce allergens or toxins that can impact human health.

Familial Hypophosphatemia is a genetic disorder characterized by low levels of phosphate in the blood (hypophosphatemia) due to impaired absorption of phosphates in the gut. This condition results from mutations in the SLC34A3 gene, which provides instructions for making a protein called NaPi-IIc, responsible for reabsorbing phosphates from the filtrate in the kidney tubules back into the bloodstream.

In familial hypophosphatemia, the impaired function of NaPi-IIc leads to excessive loss of phosphate through urine, resulting in hypophosphatemia. This condition can cause rickets (a softening and weakening of bones) in children and osteomalacia (softening of bones) in adults. Symptoms may include bowed legs, bone pain, muscle weakness, and short stature.

Familial Hypophosphatemia is inherited as an autosomal recessive trait, meaning that an individual must inherit two copies of the mutated gene (one from each parent) to develop the condition.

Biological availability is a term used in pharmacology and toxicology that refers to the degree and rate at which a drug or other substance is absorbed into the bloodstream and becomes available at the site of action in the body. It is a measure of the amount of the substance that reaches the systemic circulation unchanged, after administration by any route (such as oral, intravenous, etc.).

The biological availability (F) of a drug can be calculated using the area under the curve (AUC) of the plasma concentration-time profile after extravascular and intravenous dosing, according to the following formula:

F = (AUCex/AUCiv) x (Doseiv/Doseex)

where AUCex is the AUC after extravascular dosing, AUCiv is the AUC after intravenous dosing, Doseiv is the intravenous dose, and Doseex is the extravascular dose.

Biological availability is an important consideration in drug development and therapy, as it can affect the drug's efficacy, safety, and dosage regimen. Drugs with low biological availability may require higher doses to achieve the desired therapeutic effect, while drugs with high biological availability may have a more rapid onset of action and require lower doses to avoid toxicity.

A bioreactor is a device or system that supports and controls the conditions necessary for biological organisms, cells, or tissues to grow and perform their specific functions. It provides a controlled environment with appropriate temperature, pH, nutrients, and other factors required for the desired biological process to occur. Bioreactors are widely used in various fields such as biotechnology, pharmaceuticals, agriculture, and environmental science for applications like production of therapeutic proteins, vaccines, biofuels, enzymes, and wastewater treatment.

Chemical water pollutants refer to harmful chemicals or substances that contaminate bodies of water, making them unsafe for human use and harmful to aquatic life. These pollutants can come from various sources, including industrial and agricultural runoff, sewage and wastewater, oil spills, and improper disposal of hazardous materials.

Examples of chemical water pollutants include heavy metals (such as lead, mercury, and cadmium), pesticides and herbicides, volatile organic compounds (VOCs), polychlorinated biphenyls (PCBs), and petroleum products. These chemicals can have toxic effects on aquatic organisms, disrupt ecosystems, and pose risks to human health through exposure or consumption.

Regulations and standards are in place to monitor and limit the levels of chemical pollutants in water sources, with the aim of protecting public health and the environment.

I'm sorry for any confusion, but "Oceans and Seas" are not medical terms. Generally speaking, an ocean is a large body of saltwater that covers a majority of the Earth's surface, and a sea is a smaller body of saltwater that may be partially enclosed by land. However, if you have any questions related to marine biology or environmental science, I would be happy to try and help answer those for you!

Water purification is the process of removing or reducing contaminants in water to make it safe and suitable for specific uses, such as drinking, cooking, irrigation, or medical purposes. This is typically achieved through physical, chemical, or biological methods, or a combination thereof. The goal is to eliminate or reduce harmful substances like bacteria, viruses, parasites, heavy metals, pesticides, and other pollutants that can cause illness or negatively impact human health, aquatic life, or the environment.

The specific purification methods used may vary depending on the nature of the contaminants and the desired level of purity for the intended use. Common techniques include filtration (using various types of filters like activated carbon, ceramic, or reverse osmosis), disinfection (using chemicals like chlorine or UV light to kill microorganisms), sedimentation (allowing particles to settle and be removed), and distillation (heating water to create steam, which is then condensed back into pure water).

Zooplankton are not a medical term, but they are an important concept in biology and ecology. Zooplankton refer to small, drifting or floating animals that live in watery environments such as oceans, seas, and freshwater bodies. They include various organisms like tiny crustaceans (such as copepods and krill), jellyfish, arrow worms, and larvae of larger aquatic animals. Zooplankton play a crucial role in food chains and nutrient cycling within aquatic ecosystems.

Medical definitions of water generally describe it as a colorless, odorless, tasteless liquid that is essential for all forms of life. It is a universal solvent, making it an excellent medium for transporting nutrients and waste products within the body. Water constitutes about 50-70% of an individual's body weight, depending on factors such as age, sex, and muscle mass.

In medical terms, water has several important functions in the human body:

1. Regulation of body temperature through perspiration and respiration.
2. Acting as a lubricant for joints and tissues.
3. Facilitating digestion by helping to break down food particles.
4. Transporting nutrients, oxygen, and waste products throughout the body.
5. Helping to maintain healthy skin and mucous membranes.
6. Assisting in the regulation of various bodily functions, such as blood pressure and heart rate.

Dehydration can occur when an individual does not consume enough water or loses too much fluid due to illness, exercise, or other factors. This can lead to a variety of symptoms, including dry mouth, fatigue, dizziness, and confusion. Severe dehydration can be life-threatening if left untreated.

Calcinosis is a medical condition characterized by the abnormal deposit of calcium salts in various tissues of the body, commonly under the skin or in the muscles and tendons. These calcium deposits can form hard lumps or nodules that can cause pain, inflammation, and restricted mobility. Calcinosis can occur as a complication of other medical conditions, such as autoimmune disorders, kidney disease, and hypercalcemia (high levels of calcium in the blood). In some cases, the cause of calcinosis may be unknown. Treatment for calcinosis depends on the underlying cause and may include medications to manage calcium levels, physical therapy, and surgical removal of large deposits.

Sulfur is not typically referred to in the context of a medical definition, as it is an element found in nature and not a specific medical condition or concept. However, sulfur does have some relevance to certain medical topics:

* Sulfur is an essential element that is a component of several amino acids (the building blocks of proteins) and is necessary for the proper functioning of enzymes and other biological processes in the body.
* Sulfur-containing compounds, such as glutathione, play important roles in antioxidant defense and detoxification in the body.
* Some medications and supplements contain sulfur or sulfur-containing compounds, such as dimethyl sulfoxide (DMSO), which is used topically for pain relief and inflammation.
* Sulfur baths and other forms of sulfur-based therapies have been used historically in alternative medicine to treat various conditions, although their effectiveness is not well-established by scientific research.

It's important to note that while sulfur itself is not a medical term, it can be relevant to certain medical topics and should be discussed with a healthcare professional if you have any questions or concerns about its use in medications, supplements, or therapies.

Fibroblast Growth Factors (FGFs) are a family of growth factors that play crucial roles in various biological processes, including cell survival, proliferation, migration, and differentiation. They bind to specific tyrosine kinase receptors (FGFRs) on the cell surface, leading to intracellular signaling cascades that regulate gene expression and downstream cellular responses. FGFs are involved in embryonic development, tissue repair, and angiogenesis (the formation of new blood vessels). There are at least 22 distinct FGFs identified in humans, each with unique functions and patterns of expression. Some FGFs, like FGF1 and FGF2, have mitogenic effects on fibroblasts and other cell types, while others, such as FGF7 and FGF10, are essential for epithelial-mesenchymal interactions during organ development. Dysregulation of FGF signaling has been implicated in various pathological conditions, including cancer, fibrosis, and developmental disorders.

Bacteria are single-celled microorganisms that are among the earliest known life forms on Earth. They are typically characterized as having a cell wall and no membrane-bound organelles. The majority of bacteria have a prokaryotic organization, meaning they lack a nucleus and other membrane-bound organelles.

Bacteria exist in diverse environments and can be found in every habitat on Earth, including soil, water, and the bodies of plants and animals. Some bacteria are beneficial to their hosts, while others can cause disease. Beneficial bacteria play important roles in processes such as digestion, nitrogen fixation, and biogeochemical cycling.

Bacteria reproduce asexually through binary fission or budding, and some species can also exchange genetic material through conjugation. They have a wide range of metabolic capabilities, with many using organic compounds as their source of energy, while others are capable of photosynthesis or chemosynthesis.

Bacteria are highly adaptable and can evolve rapidly in response to environmental changes. This has led to the development of antibiotic resistance in some species, which poses a significant public health challenge. Understanding the biology and behavior of bacteria is essential for developing strategies to prevent and treat bacterial infections and diseases.

Physiologic calcification is the normal deposit of calcium salts in body tissues and organs. It is a natural process that occurs as part of the growth and development of the human body, as well as during the repair and remodeling of tissues.

Calcium is an essential mineral that plays a critical role in many bodily functions, including bone formation, muscle contraction, nerve impulse transmission, and blood clotting. In order to maintain proper levels of calcium in the body, excess calcium that is not needed for these functions may be deposited in various tissues as a normal part of the aging process.

Physiologic calcification typically occurs in areas such as the walls of blood vessels, the lungs, and the heart valves. While these calcifications are generally harmless, they can sometimes lead to complications, particularly if they occur in large amounts or in sensitive areas. For example, calcification of the coronary arteries can increase the risk of heart disease, while calcification of the lung tissue can cause respiratory symptoms.

It is important to note that pathologic calcification, on the other hand, refers to the abnormal deposit of calcium salts in tissues and organs, which can be caused by various medical conditions such as chronic kidney disease, hyperparathyroidism, and certain infections. Pathologic calcification is not a normal process and can lead to serious health complications if left untreated.

Uremia is not a disease itself, but rather it's a condition that results from the buildup of waste products in the blood due to kidney failure. The term "uremia" comes from the word "urea," which is one of the waste products that accumulate when the kidneys are not functioning properly.

In uremia, the kidneys are unable to effectively filter waste and excess fluids from the blood, leading to a variety of symptoms such as nausea, vomiting, fatigue, itching, mental confusion, and ultimately, if left untreated, can lead to coma and death. It is a serious condition that requires immediate medical attention, often involving dialysis or a kidney transplant to manage the underlying kidney dysfunction.

"Food analysis" is not a medical term per se, but it falls under the broader field of food science and nutrition. Food analysis refers to the laboratory methods and techniques used to determine the composition and quality of food products. This can include testing for nutrients (such as proteins, fats, carbohydrates, vitamins, and minerals), contaminants (like heavy metals, pesticides, or allergens), and other components that may affect the safety, quality, or authenticity of food.

The results of food analysis can be used to ensure compliance with regulatory standards, develop new food products, assess the nutritional value of diets, investigate food-borne illnesses, and monitor trends in food consumption. While not a medical definition, food analysis is an important tool for promoting public health and preventing diet-related diseases.

I'm happy to help, but it seems there might be some confusion in your question. "Lakes" is not a medical term that has a specific definition in the context of medicine or healthcare. It is a geographical term used to describe large bodies of water surrounded by land. If you have any questions related to health, medicine, or healthcare, I would be happy to try and help answer those for you!

Polyamines are organic compounds with more than one amino group (-NH2) and at least one carbon atom bonded to two or more amino groups. They are found in various tissues and fluids of living organisms and play important roles in many biological processes, such as cell growth, differentiation, and apoptosis (programmed cell death). Polyamines are also involved in the regulation of ion channels and transporters, DNA replication and gene expression. The most common polyamines found in mammalian cells are putrescine, spermidine, and spermine. They are derived from the decarboxylation of amino acids such as ornithine and methionine. Abnormal levels of polyamines have been associated with various pathological conditions, including cancer and neurodegenerative diseases.

In medical terms, the term "atmosphere" is not typically used as a standalone definition or diagnosis. However, in some contexts, it may refer to the physical environment or surroundings in which medical care is provided. For example, some hospitals and healthcare facilities may have different atmospheres depending on their specialties, design, or overall ambiance.

Additionally, "atmosphere" may also be used more broadly to describe the social or emotional climate of a particular healthcare setting. For instance, a healthcare provider might describe a patient's home atmosphere as warm and welcoming, or a hospital ward's atmosphere as tense or chaotic.

It is important to note that "atmosphere" is not a medical term with a specific definition, so its meaning may vary depending on the context in which it is used.

I'm sorry for any confusion, but "geology" is not a medical term. It is a scientific discipline that deals with the Earth's physical structure and substance, its history, and the processes that act on it. If you have any questions about medical terminology or concepts, I would be happy to help!

Trace elements are essential minerals that the body needs in very small or tiny amounts, usually less than 100 milligrams per day, for various biological processes. These include elements like iron, zinc, copper, manganese, fluoride, selenium, and iodine. They are vital for maintaining good health and proper functioning of the human body, but they are required in such minute quantities that even a slight excess or deficiency can lead to significant health issues.

Oxidation-Reduction (redox) reactions are a type of chemical reaction involving a transfer of electrons between two species. The substance that loses electrons in the reaction is oxidized, and the substance that gains electrons is reduced. Oxidation and reduction always occur together in a redox reaction, hence the term "oxidation-reduction."

In biological systems, redox reactions play a crucial role in many cellular processes, including energy production, metabolism, and signaling. The transfer of electrons in these reactions is often facilitated by specialized molecules called electron carriers, such as nicotinamide adenine dinucleotide (NAD+/NADH) and flavin adenine dinucleotide (FAD/FADH2).

The oxidation state of an element in a compound is a measure of the number of electrons that have been gained or lost relative to its neutral state. In redox reactions, the oxidation state of one or more elements changes as they gain or lose electrons. The substance that is oxidized has a higher oxidation state, while the substance that is reduced has a lower oxidation state.

Overall, oxidation-reduction reactions are fundamental to the functioning of living organisms and are involved in many important biological processes.

Nucleic acids are biological macromolecules composed of linear chains of nucleotides. They play crucial roles in the structure and function of cells, serving as the primary information-carrying molecules in all known forms of life. The two main types of nucleic acids are deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). DNA is responsible for storing genetic information in a stable form that can be passed down from generation to generation, while RNA plays a key role in translating the genetic code stored in DNA into functional proteins.

Each nucleotide consists of a sugar molecule, a phosphate group, and a nitrogenous base. The sugar in DNA is deoxyribose, while in RNA it is ribose. The nitrogenous bases found in both DNA and RNA include adenine (A), guanine (G), and cytosine (C). Thymine (T) is found in DNA, but uracil (U) takes its place in RNA. These nucleotides are linked together by phosphodiester bonds between the sugar of one nucleotide and the phosphate group of another, forming a long, helical structure with backbones made up of alternating sugar and phosphate groups.

The sequence of these nitrogenous bases along the nucleic acid chain encodes genetic information in the form of codons, which are sets of three consecutive bases that specify particular amino acids or signals for protein synthesis. This information is used to direct the synthesis of proteins through a process called transcription (converting DNA to RNA) and translation (converting RNA to protein).

In summary, nucleic acids are essential biomolecules composed of chains of nucleotides that store, transmit, and express genetic information in cells. They consist of two main types: DNA and RNA, which differ in their sugar type, nitrogenous bases, and functions.

Acetates, in a medical context, most commonly refer to compounds that contain the acetate group, which is an functional group consisting of a carbon atom bonded to two hydrogen atoms and an oxygen atom (-COO-). An example of an acetate is sodium acetate (CH3COONa), which is a salt formed from acetic acid (CH3COOH) and is often used as a buffering agent in medical solutions.

Acetates can also refer to a group of medications that contain acetate as an active ingredient, such as magnesium acetate, which is used as a laxative, or calcium acetate, which is used to treat high levels of phosphate in the blood.

In addition, acetates can also refer to a process called acetylation, which is the addition of an acetyl group (-COCH3) to a molecule. This process can be important in the metabolism and regulation of various substances within the body.

A kidney, in medical terms, is one of two bean-shaped organs located in the lower back region of the body. They are essential for maintaining homeostasis within the body by performing several crucial functions such as:

1. Regulation of water and electrolyte balance: Kidneys help regulate the amount of water and various electrolytes like sodium, potassium, and calcium in the bloodstream to maintain a stable internal environment.

2. Excretion of waste products: They filter waste products from the blood, including urea (a byproduct of protein metabolism), creatinine (a breakdown product of muscle tissue), and other harmful substances that result from normal cellular functions or external sources like medications and toxins.

3. Endocrine function: Kidneys produce several hormones with important roles in the body, such as erythropoietin (stimulates red blood cell production), renin (regulates blood pressure), and calcitriol (activated form of vitamin D that helps regulate calcium homeostasis).

4. pH balance regulation: Kidneys maintain the proper acid-base balance in the body by excreting either hydrogen ions or bicarbonate ions, depending on whether the blood is too acidic or too alkaline.

5. Blood pressure control: The kidneys play a significant role in regulating blood pressure through the renin-angiotensin-aldosterone system (RAAS), which constricts blood vessels and promotes sodium and water retention to increase blood volume and, consequently, blood pressure.

Anatomically, each kidney is approximately 10-12 cm long, 5-7 cm wide, and 3 cm thick, with a weight of about 120-170 grams. They are surrounded by a protective layer of fat and connected to the urinary system through the renal pelvis, ureters, bladder, and urethra.

Food preservatives are substances added to foods to prevent or slow down spoilage caused by microorganisms such as bacteria, yeasts, and molds, or to retard quality deterioration due to oxidation or other chemical reactions. They work by inhibiting the growth of microorganisms, preventing enzymatic reactions that cause spoilage, or scavenging oxygen that can lead to food degradation. Examples of commonly used food preservatives include sodium benzoate, potassium sorbate, sulfites, and nitrites. It is important to note that while food preservatives play a crucial role in maintaining the safety and quality of our food supply, excessive consumption of certain preservatives may have adverse health effects.

Catalysis is the process of increasing the rate of a chemical reaction by adding a substance known as a catalyst, which remains unchanged at the end of the reaction. A catalyst lowers the activation energy required for the reaction to occur, thereby allowing the reaction to proceed more quickly and efficiently. This can be particularly important in biological systems, where enzymes act as catalysts to speed up metabolic reactions that are essential for life.

Hyperparathyroidism is a condition in which the parathyroid glands produce excessive amounts of parathyroid hormone (PTH). There are four small parathyroid glands located in the neck, near or within the thyroid gland. They release PTH into the bloodstream to help regulate the levels of calcium and phosphorus in the body.

In hyperparathyroidism, overproduction of PTH can lead to an imbalance in these minerals, causing high blood calcium levels (hypercalcemia) and low phosphate levels (hypophosphatemia). This can result in various symptoms such as fatigue, weakness, bone pain, kidney stones, and cognitive issues.

There are two types of hyperparathyroidism: primary and secondary. Primary hyperparathyroidism occurs when there is a problem with one or more of the parathyroid glands, causing them to become overactive and produce too much PTH. Secondary hyperparathyroidism develops as a response to low calcium levels in the body due to conditions like vitamin D deficiency, chronic kidney disease, or malabsorption syndromes.

Treatment for hyperparathyroidism depends on the underlying cause and severity of symptoms. In primary hyperparathyroidism, surgery to remove the overactive parathyroid gland(s) is often recommended. For secondary hyperparathyroidism, treating the underlying condition and managing calcium levels with medications or dietary changes may be sufficient.

Carbon radioisotopes are radioactive isotopes of carbon, which is an naturally occurring chemical element with the atomic number 6. The most common and stable isotope of carbon is carbon-12 (^12C), but there are also several radioactive isotopes, including carbon-11 (^11C), carbon-14 (^14C), and carbon-13 (^13C). These radioisotopes have different numbers of neutrons in their nuclei, which makes them unstable and causes them to emit radiation.

Carbon-11 has a half-life of about 20 minutes and is used in medical imaging techniques such as positron emission tomography (PET) scans. It is produced by bombarding nitrogen-14 with protons in a cyclotron.

Carbon-14, also known as radiocarbon, has a half-life of about 5730 years and is used in archaeology and geology to date organic materials. It is produced naturally in the atmosphere by cosmic rays.

Carbon-13 is stable and has a natural abundance of about 1.1% in carbon. It is not radioactive, but it can be used as a tracer in medical research and in the study of metabolic processes.

Liquid chromatography (LC) is a type of chromatography technique used to separate, identify, and quantify the components in a mixture. In this method, the sample mixture is dissolved in a liquid solvent (the mobile phase) and then passed through a stationary phase, which can be a solid or a liquid that is held in place by a solid support.

The components of the mixture interact differently with the stationary phase and the mobile phase, causing them to separate as they move through the system. The separated components are then detected and measured using various detection techniques, such as ultraviolet (UV) absorbance or mass spectrometry.

Liquid chromatography is widely used in many areas of science and medicine, including drug development, environmental analysis, food safety testing, and clinical diagnostics. It can be used to separate and analyze a wide range of compounds, from small molecules like drugs and metabolites to large biomolecules like proteins and nucleic acids.

Seawater is not a medical term, but it is a type of water that covers more than 70% of the Earth's surface. Medically, seawater can be relevant in certain contexts, such as in discussions of marine biology, environmental health, or water safety. Seawater has a high salt content, with an average salinity of around 3.5%, which is much higher than that of freshwater. This makes it unsuitable for drinking or irrigation without desalination.

Exposure to seawater can also have medical implications, such as in cases of immersion injuries, marine envenomations, or waterborne illnesses. However, there is no single medical definition of seawater.

Phosphorus isotopes data from The Berkeley Laboratory Isotopes Project's "Standard Atomic Weights: Phosphorus". CIAAW. 2013. ... Isotopes of phosphorus, Phosphorus, Lists of isotopes by element). ... Although phosphorus (15P) has 22 isotopes from 26P to 47P, only 31P is stable; as such, phosphorus is considered a monoisotopic ... Has 1 halo proton 32P is a radioactive isotope of phosphorus with relative atomic mass 31.973907 and half-life of 14.26 days. ...
Discovery of a new isotope, phosphorus-33. Separation of high-purity rare-earth oxides in kilogram quantities. Development of a ... Discovery of a new isotope, copper-69. Conducted the first successful operation of an isotope separator connected to a reactor ... As part of that effort, the Lab built a 5-megawatt heavy water reactor for neutron diffraction studies and additional isotope ...
... (32P) is a radioactive isotope of phosphorus. The nucleus of phosphorus-32 contains 15 protons and 17 neutrons, ... one more neutron than the most common isotope of phosphorus, phosphorus-31. Phosphorus-32 only exists in small quantities on ... Phosphorus is abundant in biological systems and, as a radioactive isotope is almost chemically identical with stable isotopes ... Phosphorus is found in many organic molecules and so phosphorus-32 has many applications in medicine, biochemistry, and ...
Two radioactive isotopes of phosphorus have half-lives suitable for biological scientific experiments. These are: 32 P, a beta- ... Elemental phosphorus was first isolated as white phosphorus in 1669. In white phosphorus, phosphorus atoms are arranged in ... Violet phosphorus is a form of phosphorus that can be produced by day-long annealing of red phosphorus above 550 °C. In 1865, ... Red phosphorus may be formed by heating white phosphorus to 250 °C (482 °F) or by exposing white phosphorus to sunlight. ...
There are both radioactive and stable cosmogenic isotopes. Some of these radioisotopes are tritium, carbon-14 and phosphorus-32 ... Cosmogenic isotopes (or cosmogenic nuclides) are rare isotopes created when a high-energy cosmic ray interacts with the nucleus ... Finally, the ratio of the rare cosmogenic isotope to the common isotope is measured using accelerator mass spectrometry. The ... The caesium isotopes in the fallout have had an effect on farming. [2] A large amount of caesium was released during the ...
If the definition refers only to one isotope (as that of the dalton does) or to a specific isotope ratio, e.g. Vienna Standard ... and phosphorus-31 (31P). Fluorine and phosphorus are monoisotopic, with hydrogen nearly so. 1H NMR, 19F NMR and 31P NMR allow ... Such isotopes are used in a variety of analytical and forensic applications. Isotopic mass data from Atomic Weights and ... Thus, the element's natural isotopic abundance is dominated by one isotope that is either stable or very long-lived. There are ...
Usually, the probe is marked with a radioactive isotope of phosphorus. Following the hybridization, autoradiography or other ...
He set up an isotope lab in 1950 to use labelled phosphorus to study the movement and synthesis of brain lipids. Rossiter ... He made use of radioactive phosphorus isotopes to study the biochemistry of glycerophosphatides and phosphoinositides. Rossiter ...
For example, the phosphate ion containing radioactive phosphorus-32 is [32PO4]3−. Also a study involving stable isotope ratios ... Although isotopes are more relevant to nuclear chemistry or stable isotope chemistry than to conventional chemistry, different ... isotopes may be indicated with a prefixed superscript in a chemical formula. ...
Since phosphorus is contained in DNA but not amino acids, radioactive phosphorus-32 was used to label the DNA contained in the ... Hershey and Chase inserted the radioactive elements in the bacteriophages by adding the isotopes to separate media within which ... This procedure was performed once for the sulfur-labeled phages and once for phosphorus-labeled phages. The labeled progeny ... The progeny of the phages that were labeled with radioactive phosphorus remained labeled, whereas the progeny of the phages ...
In addition to the above light elements, tritium and isotopes of aluminium, carbon (carbon-14), phosphorus (phosphorus-32), ... These isotopes are produced within earth materials such as rocks or soil, in Earth's atmosphere, and in extraterrestrial items ... By measuring cosmogenic isotopes, scientists are able to gain insight into a range of geological and astronomical processes. ... Ray Isotope Spectrometer[permanent dead link] University of Leeds paper[permanent dead link], proceedings of the 26th ICRC.( ...
Lajtha, Kate; Schlesinger, William H. (1988). "The Biogeochemistry of Phosphorus Cycling and Phosphorus Availability Along a ... Kate Lajtha is an ecologist known for her use of stable isotopes to examine biogeochemical cycling in soils. Lajtha has a B.A. ... Lajtha, Kate; Michener, Robert H. (1994). Stable isotopes in ecology and environmental science. Blackwell Scientific ...
While 89Sr with a half-life of 50.6 days is used to treat bone cancer, 90Sr is an isotope of concern, with a half-life of 28.90 ... The bones are largely composed of calcium and phosphorus in the form of tricalcium phosphate. W. Wesley Campbell and David M. ... Hamilton, Joseph G.; Soley, Mayo H. (1939). "Studies In Iodine Metabolism by the Use of a New Radioactive Isotope of Iodine". ... It surmised that the radioactive isotope strontium-90 (Sr-90) represented the most serious threat to human health from nuclear ...
Melander, Lars (1960). Isotope Effects on Reaction Rates. New York: Ronald Press. Wang, Yong; Kumar, Devesh; Yang, Chuanlu; Han ... In 1955, Westheimer published the first of many articles on the chemistry of phosphate esters and phosphorus derivatives. He ... His work on the magnitude of kinetic isotope effects (KIEs) is still the basis of understanding in the field.: 418 Transition ... Westheimer, F. H. (1 June 1961). "The Magnitude of the Primary Kinetic Isotope Effect for Compounds of Hydrogen and Deuterium ...
The isotope needed for nuclear fission of uranium is 235U, a minor component of natural uranium, which is mainly 238U. Brues, A ... and excretion of phosphorus". J. Biol. Chem. 123 (1): 185-198. Cohn, W. E. (1943). "The determination of hemoglobin in tissue ... There he introduced the use of ion-exchange chromatography for separation of isotopes needed for developing the atomic bomb. On ... Cohn, W. E.; Greenberg, D. M. (1938). "Studies in mineral metabolism with the aid of artificial radioactive isotopes I. ...
He published his first article using the phosphorus isotope 31P to probe phospholipids in 2004. He became a fellow of the ... Isotope-detected 1 H NMR studies of proteins: A general strategy for editing interproton nuclear Overhauser effects by ... isotope labeling, nuclear Overhauser effect, proteins and their macromolecules in solution, phospholipid approaches. He devised ...
Brucer told a conference that the use of radio-isotopes of iodine, gold and phosphorus was becoming increasingly commonplace. ... Against cancer we have the same problem with isotopes as with the x-ray and radium- minimizing the damage to good cells while ... In 1956, Brucer said of progress in his field: Isotopes remain potentially wonderful but the challenge now is how to handle ... It could cause us to stop radiation therapy and diagnosis with radioactive isotopes... the neglect of these things would be ...
Some elements, such as phosphorus and fluorine, only exist as a single isotope, with a natural abundance of 100%. Abundance of ... and by production of a given isotope as a daughter of natural radioactive isotopes (as in the case of radiogenic isotopes of ... This is because 238U is much more stable than 235U or 234U, as the half-life of each isotope reveals: 4.468 × 109 years for ... The abundance of an isotope varies from planet to planet, and even from place to place on the Earth, but remains relatively ...
B]ioavailable phosphorus - phosphorus that can be utilized by plants and bacteria - is only a fraction of the total, according ... are notable for their inclusion of significant quantities of radioactive uranium isotopes. This is a concern because ... the supply of phosphorus was estimated to run out in 345 years. However, some scientists thought that a "peak phosphorus" would ... Phosphorus oxyanions, Phosphates, Industrial minerals, Concrete admixtures, Phosphorus(V) compounds). ...
Several of the essays form a sequence explaining the discovery and uses of isotopes. In the title essay, Asimov argues that ... while other chapters describe the alchemical and biochemical histories of phosphorus. In a discussion on space travel, Asimov ... Some chapters focus on chemistry; one chapter discusses naturally occurring radioactive isotopes in the body, ...
Upward and Lateral Movement of Salt in Certain Plants as Indicated by Radioactive Isotopes of Potassium, Sodium, and Phosphorus ...
The positive δ13C isotope excursion found at the Cenomanian-Turonian boundary is one of the main carbon isotope events of the ... The phosphorus retention ability of seafloor sediments declined during OAE2, revealed by a decline in reactive phosphorus ... Other studies linked the lead (Pb) isotopes of OAE-2 to the Caribbean-Colombian and the Madagascar LIPs. An osmium isotope ... Within the positive carbon isotope excursion, short eccentricity scale carbon isotope variability is documented in a ...
Hertz studied the application of radioactive phosphorus and the influences of hormones on cancer as displayed by isotope ... However, this isotope has a half-life of only 25 minutes, rendering it impractical as a therapeutic or diagnostic agent. Human ... With a half-life of 8 days, this isotope was better suited to practical medical applications than I-128. The building of the ... Hertz worked with the government to centralize an agency to handle the distribution of radioactive isotopes for use by private ...
The 188Re isotope is also used for the rhenium-SCT (skin cancer therapy). The treatment uses the isotope's properties as a beta ... Rhenium catalysts are very resistant to chemical poisoning from nitrogen, sulfur and phosphorus, and so are used in certain ... The isotope rhenium-186m is notable as being one of the longest lived metastable isotopes with a half-life of around 200,000 ... The isotopes 186Re and 188Re are radioactive and are used for treatment of liver cancer. They both have similar penetration ...
Particular emphasis is placed on the study of carbon, nitrogen, sulfur, iron, and phosphorus cycles. Biogeochemistry is a ... Carbon isotopes as biochemical recorders of life over 3.8 Ga of Earth history: Evolution of a concept. In: Precambrian Research ... Many researchers investigate the biogeochemical cycles of chemical elements such as carbon, oxygen, nitrogen, phosphorus and ... phosphorus, selenium, iron and sulfur, as well as molecular cycles, such as for water and silica. There are also macroscopic ...
Elemental phosphorus exists in two major forms-white phosphorus and red phosphorus-but due to its high reactivity, phosphorus ... In the universe, argon-36 is by far the most common argon isotope, being the preferred argon isotope produced by stellar ... Phosphorus (symbol P) is a multivalent nonmetal of the nitrogen group, phosphorus as a mineral is almost always present in its ... The first form of elemental phosphorus to be produced (white phosphorus, in 1669) emits a faint glow upon exposure to oxygen - ...
... primarily iodine-131 and phosphorus-32 for cancer diagnosis and treatment. Isotopes were also used in biological, industrial ... It eventually became the preferred method of uranium isotope separation, being far more economical. Electromagnetic isotope ... The possibility of separating the isotopes was also considered and rejected, as plutonium-240 is even harder to separate from ... The most promising but also the most challenging method of isotope separation was gaseous diffusion. Graham's law states that ...
The most abundant naturally occurring isotopes of hydrogen and phosphorus (for example) are both magnetically susceptible and ... This occurs when an isotope has a nonzero nuclear spin, meaning an odd number of protons and/or neutrons (see Isotope). ... High resolution NMR instead probes molecules using the rarer 15 N isotope, which has spin-1/2. Many isotopes of chemical ... If γ is positive (true for most isotopes used in NMR) then m = 1/2 is the lower energy state. The energy difference between the ...
... a phosphorus isotope. They concluded that irradiation could produce new radioactive elements. From the outset, they anticipated ... As the CEA lacked the necessary technical and financial resources to enrich natural uranium to its fissile isotope (235U), it ... In February 1939, Niels Bohr confirmed that inside natural uranium, there exist two isotopes; 238U and 235U. However, only ... In late 1933, they used alpha radiation to bombard aluminum foil and demonstrated the production of radioactive phosphorus-30, ...
... and injections of radioactive isotopes. The amount of radioactive phosphorus-32 injected into some of the patients, 500 ...
Phosphorus isotopes data from The Berkeley Laboratory Isotopes Projects "Standard Atomic Weights: Phosphorus". CIAAW. 2013. ... Isotopes of phosphorus, Phosphorus, Lists of isotopes by element). ... Although phosphorus (15P) has 22 isotopes from 26P to 47P, only 31P is stable; as such, phosphorus is considered a monoisotopic ... Has 1 halo proton 32P is a radioactive isotope of phosphorus with relative atomic mass 31.973907 and half-life of 14.26 days. ...
A review of phosphate oxygen isotope values in global bedrocks: characterising a critical endmember to the soil phosphorus ... 2021 A review of phosphate oxygen isotope values in global bedrocks: characterising a critical endmember to the soil phosphorus ... especially in areas of soil research which use this isotope signature as a proxy for biological cycling of phosphorus (P). For ... Understanding the phosphate oxygen isotope (δ18O‐PO4) composition of bedrock phosphate sources is becoming ever more important ...
... isotope ratio (& delta;N-15) in soils of temperate and boreal fores ... Spatial patterns of nitrogen isotope ratios in forest soils are related to latitude and soil phosphorus concentration. Spohn, ... Nitrogen isotopes; Temperate forest; Boreal forest; Latitude; Phosphorus concentration; Atmospheric nitrogen deposition ... The aim of this study was to identify the parameters that affect the nitrogen (N) isotope ratio (& delta;N-15) in soils of ...
Use of Phosphorus Isotopes for Improving Phosphorus Management in Agricultural Systems. TECDOC Series - 1805 ...
Radioactive isotopes of phosphorus include *32P; a beta-emitter (1.71 MeV) with a half-life of 14.3 days which is used ... through the intermediates phosphorus chlorides and the two phosphorus sulfides: phosphorus pentasulfide, and phosphorus ... Red phosphorus may be formed by heating white phosphorus to 250°C (482°F) or by exposing white phosphorus to sunlight. ... Due to its high reactivity, phosphorus is never found as a free element in nature. One form of phosphorus (white phosphorus) ...
To see the isotopes that exist in the ScientificConstants package for a particular element, use the GetIsotopes function with ... Home : Support : Online Help : Science and Engineering : Scientific Constants : Initial Elements and Isotopes ...
Phosphorus magnetic resonance spectroscopy (31P-MRS) was used to study in vivo the energy metabolism of brain and skeletal ... Phosphorus Isotopes* * Phosphorylation * Point Mutation / genetics * Retinitis Pigmentosa / complications * Retinitis ... Phosphorus magnetic resonance spectroscopy (31P-MRS) was used to study in vivo the energy metabolism of brain and skeletal ...
where Rsample is the isotope ratio 15N/14N of the sample and Rstandard is the isotope ratio of atmospheric N2 (i.e., Rstandard ... S.S., C.C. and L.H. did the stable isotope analysis. J.d.H., H.J.B., P.M.V. and J.H. analyzed the data. J.d.H., P.M.V., M.J.A.V ... How to cite this article: den Haan, J. et al. Nitrogen and phosphorus uptake rates of different species from a coral reef ... Nitrogen and phosphorus uptake rates of different species from a coral reef community after a nutrient pulse. *Joost den Haan. ...
Isotopes of phosphorus == Although twenty three isotopes of phosphorus are known ,ref>The Berkeley Laboratory Isotopes Project ... Allotropes of phosphorus == {{Image,Phosphorus P4 atomic structure.jpg,right,200px,Structure of white phosphorus.}} Both ... Glow of phosphorus== In the dark pure white phosphorus glows, which explains the name of the element. This greenish glow ... Antoine Lavoisier]] recognized phosphorus as an element in 1777. Bone ash was the major source of phosphorus until the 1840s. ...
Isotopes are atomic species of the same chemical element (and therefore with the same atomic number (Z) or number of protons) ... Therefore each isotope of an element has a different mass number (A), which is the simple summation of the number of protons ... For example, the element carbon has six protons and its commonest isotope on earth has six neutrons, resulting in a mass number ... IUPAC Periodic Table of the Elements and Isotopes (IPTEI) for the Education Community (IUPAC Technical Report). Pure and ...
The results of a two-component isotope mass balance equation using δ13C and δ34S values for Layari and Malir rivers and coastal ... and radioactive isotope of hydrogen (tritium) have been applied in combination with conventional techniques (chemical) to ... Stable isotopes of carbon (δ13C), sulfur (δ34S), oxygen (δ18O), hydrogen (δ2H), nitrogen (δ15N), ... The morphological differences are indicative of phosphorus and nitrogen limitation [McKee et al., 2002]. ...
Intruder States in Neutron Rich Phosphorus Isotopes Near N=28 15m Longs Peak Longs Peak. ... Particle-bound isotopes along the neutron dripline have been searched for fluorine (Z = 9) and neon (Z = 10) isotopes at the ... The structure of odd Z phosphorus isotopes (N = 22 - 25) were investigated at the National Superconducting Cyclotron Laboratory ... It is thus found that the most neutron-rich isotopes 31F and 34Ne previously observed are the heaviest of these isotopes. The ...
title = "Serum phosphorus levels associate with coronary atherosclerosis in young adults",. abstract = "Phosphorus levels ... Serum phosphorus levels associate with coronary atherosclerosis in young adults. Robert N. Foley, Allan J. Collins, Charles A. ... Serum phosphorus levels associate with coronary atherosclerosis in young adults. Journal of the American Society of Nephrology ... Serum phosphorus levels associate with coronary atherosclerosis in young adults. In: Journal of the American Society of ...
Isotope geochemistry (1) Era and Period. Facet list. * Cenozoic (7) * Tertiary (7) ...
Objective 1B: Phosphate isotope analysis. Pair the nutrient analysis in objectives 1A-1B with a more detailed analysis of P-18O ... The water extractable soil phosphorus isotopic signature was consistent during the spring until the tile drains began to dry- ... We will also include the analysis of water isotopes (Delta o-18, Delta h-2) from the tile drain and soil water to coincide with ... In 2020, alab-based approach was developed to analyze P-18O isotope signatures of phosphate in water samples. We were able to ...
Naturally occurring isotopes: 180 (0.135%); 182 (26.4%); 183 (14.4%); 184 (30.6%); 186 (28.4%).;Hardness: 6.5-7.5. Specific ... NOT AFFECTED BY SULFUR OR PHOSPHORUS; GOOD ELECTRICAL CONDUCTIVITY;VIGOROUS REACTION WITH BROMINE TRIFLUORIDE, CHLORINE ...
Lec 24 - Phosphorus Product (Quiz). Lec 25 - Empirical Formula (NB). Lec 26 - Isotopes (NB). ...
... boron and magnesium with alpha particles to produce isotopes of nitrogen, phosphorus, silicon and aluminum. They received the ...
Spirulinas phosphorus content makes it helpful as part of a tooth remineralisation regimen. ... Emerging evidence suggests that it binds with radioactive isotopes and may be useful for radioactivity exposure or radiation ...
The next step is to test this strategy in mice, as well as other isotopes such as phosphorus-32, which could be incorporated ... To take advantage of this, her team have now armed the bacteria with a radioactive payload - attaching the isotope rhenium-188 ...
Here, we report on a previously overlooked source of prebiotic phosphorus from interstellar phosphine (PH3) that produces key ... Here, the authors investigate the potential of phosphine-doped astrochemical analog ices to form phosphorus oxoacids as ... Extraterrestrial sources may have provided prebiotic phosphorus to the early Earth. ... an understanding of the facile synthesis of oxoacids is essential to untangle the origin of water-soluble prebiotic phosphorus ...
Most stable isotopes of phosphorus. iso NA half-life DM DE (MeV) DP ... Phosphorus, 15P. waxy white (yellow cut), red (granules centre left, chunk centre right), and violet phosphorus ... Phosphorus at The Periodic Table of Videos (University of Nottingham). *Further warnings of toxic effects and recommendations ... Emsley, John (2000). The Shocking history of Phosphorus. A biography of the Devils Element. London: MacMillan. ISBN 0-333- ...
Tracing sources and cycling of phosphorus in Peru margin sediments using oxygen isotopes in phosphates ... Tracing sources and cycling of phosphorus in Peru margin sediments using oxygen isotopes in phosphates. Leg/Site/Hole:. Related ... isotope ratios; isotopes; Leg 201; marine sediments; O-18/O-16; Ocean Drilling Program; organic compounds; oxygen; Pacific ... Isotope geochemistry; Oceanography; authigenic minerals; continental margin; detritus; diagenesis; East Pacific; Equatorial ...
The water samples collected over a two-year period will be analyzed for nutrients (e.g. nitrogen, phosphorus), silica, stable ... isotopes and suspended sediments. This will allow scientists to quantify nutrient loads being contributed from agricultural ...
Mass specra and isotopes : being the twenty-sixth Robert Boyle lecture delivered before the Junior Scientific Club of the ... Shape of the phosphorus 32 beta energy spectrum. (United States Atomic Energy Commission, Technical Information Service, 1957) ... Isotope shift and wavelengths of the curium spectrum. ([Lawrence] Radiation Laboratory, 1955), by John G. Conway, Ralph D. ... Note on the spectrum of the isotopes of lead. The structure of the bismuth line [lambda] 4722 .... ([Chicago, 1918), by Lester ...
... with the objective of observing the distribution in the rat of organic compounds of phosphorus labelled with the P32 isotope as ... of inorganic phosphate in animal tissues is well known but was included in this work for comparison with the organic phosphorus ...
H+]. The oxidation of MeCDO exhibited a substantial kinetic isotope effect (. k. H/. k. D = 4.33 at 303 K). The role of ... Oxidation of lower phosphorus oxyacids by benzyltrimethylammonium dichloroiodate (BTACI), in the presence of zinc chloride, ... The oxidation of α-deuteriomandelic acid exhibits the presence of a substantial kinetic isotope effect (. k. H. /k. D. = 5.91 ... The oxidation of deuterioformic acid showed the presence of a primary kinetic isotope effect (. k. H/. k. D≈4). An increase in ...
We demonstrate the utility of phosphate oxygen isotope measurements for tracking anthropogenic phosphorus loadings with ... Microbial activity acts to equilibrate the oxygen isotope composition of PO4 with that of ambient water as a function of ... In such cases, disequilibrated oxygen isotope compositions for dissolved PO4 may prevail and provide a diagnostic source signal ...
For example, a radioactive isotope of phosphorus, prepared in solutions of sodium phosphate can be injected into animals and ... This show that the radio-phosphorus content in human blood falls after only 2 hours to just 2% of its original amount as it ... In 1946, Abelson returned to the Carnegie Institution and pioneered in utilizing radioactive isotopes. As director of the ... was the corecipient of the 1996 Nobel Prize for Physics for their discoveryof superfluidity in the isotope helium-3. As helium ...
  • The longest-lived radioactive isotopes are 33P with a half-life of 25.34 days and 32P with a half-life of 14.268 days. (wikipedia.org)
  • Emerging evidence suggests that it binds with radioactive isotopes and may be useful for radioactivity exposure or radiation therapy. (shokuikuaustralia.com)
  • In contrast are radioactive isotopes . (healthengine.com.au)
  • The radioactive isotopes can also be implanted directly into the tumour or into body cavities. (healthengine.com.au)
  • If radioactive isotopes are left inside the person they will of course continue to emit radiation. (healthengine.com.au)
  • Isotope Geochemistry, Geochronology. (uj.ac.za)
  • This course will examine the long-term record of global change as reflected in sedimentary rocks, fossil faunas and floras and low-temperature isotope geochemistry. (laurentian.ca)
  • White phosphorus is insoluble in water but soluble in carbon disulfide. (wikidoc.org)
  • For example, the element carbon has six protons and its commonest isotope on earth has six neutrons, resulting in a mass number of 12 1 . (radiopaedia.org)
  • Stable isotopes of carbon (δ13C), sulfur (δ34S), oxygen (δ18O), hydrogen (δ2H), nitrogen (δ15N), and radioactive isotope of hydrogen (tritium) have been applied in combination with conventional techniques (chemical) to investigate Karachi coastal water pollution due to Layari and Malir rivers, which mainly carry the domestic and industrial wastewater of Karachi Metropolitan. (intechopen.com)
  • In the laboratory, the technician will process and characterize sediment samples for a variety of parameters, including chemical analysis of carbon, nitrogen, and phosphorus and preparation of samples for isotope analysis. (umd.edu)
  • Our results suggest that cool, ridge flank hydrothermal systems are a net source of inorganic carbon to the oceans and that this carbon has a depleted isotope signature. (darkenergybiosphere.org)
  • Her PhD research was based on how carbon, nitrogen and phosphorus fertilization in soil affects microbial nitrogen transformation and nitrogen loss as nitrous oxide emission and nitrate leaching from a grassland soil, in presence and absence of plants. (edu.au)
  • White phosphorus (P 4 ) exists as individual molecules made up of four atoms in a tetrahedral arrangement, resulting in very high ring strain and instability. (wikidoc.org)
  • White phosphorus is a yellow, waxy transparent solid. (wikidoc.org)
  • Red phosphorus may be formed by heating white phosphorus to 250°C (482°F) or by exposing white phosphorus to sunlight. (wikidoc.org)
  • Red phosphorus does not catch fire in air at temperatures below 240°C, whereas white phosphorus ignites at about 30°C. (wikidoc.org)
  • Structure of white phosphorus. (citizendium.org)
  • White phosphorus and yellow arsenic both have four atoms arranged in a tetrahedral structure in which each atom is bound to the other three atoms by a single bond. (citizendium.org)
  • The toxicity of white phosphorus led to its discontinued use in matches. (citizendium.org)
  • Its density (2.34 kg/L) is higher than that of white phosphorus. (citizendium.org)
  • The water samples collected over a two-year period will be analyzed for nutrients (e.g. nitrogen, phosphorus), silica, stable isotopes and suspended sediments. (kyfb.com)
  • Stable isotopes : natural and anthropogenic sulphur in the environment / edited by H. R. Krouse and V. A. Grinenko. (who.int)
  • A multivalent nonmetal of the nitrogen group , phosphorus is commonly found in inorganic phosphate rocks . (wikidoc.org)
  • This process is similar to the first synthesis of phosphorus from calcium phosphate in urine. (wikidoc.org)
  • Objective 1B: Phosphate isotope analysis. (usda.gov)
  • Pair the nutrient analysis in objectives 1A-1B with a more detailed analysis of P-18O isotope signatures of phosphate in tile-drain water samples. (usda.gov)
  • In 2020, alab-based approach was developed to analyze P-18O isotope signatures of phosphate in water samples. (usda.gov)
  • We demonstrate the utility of phosphate oxygen isotope measurements for tracking anthropogenic phosphorus loadings with measurements on sewage treatment plant effluent, the Connecticut River, and an aquifer on Cape Cod. (confex.com)
  • The odour of combustion of this form has a characteristic garlic smell, and samples are commonly coated with white "(di) phosphorus pentoxide ", which consists of P 4 O 10 tetrahedra with oxygen inserted between the phosphorus atoms and at their vertices. (wikidoc.org)
  • By the 18th century it was known that in pure oxygen phosphorus does not glow at all, [8] there is only a range of partial pressure where it does. (wikidoc.org)
  • Microbial activity acts to equilibrate the oxygen isotope composition of PO 4 with that of ambient water as a function of temperature. (confex.com)
  • In such cases, disequilibrated oxygen isotope compositions for dissolved PO 4 may prevail and provide a diagnostic source signal. (confex.com)
  • Both the white and red allotropes of phosphorus are insoluble in water. (citizendium.org)
  • k obs = a + b [H + ]. The oxidation of MeCDO exhibited a substantial kinetic isotope effect ( k H / k D = 4.33 at 303 K). The role of aldehyde hydrate in the oxidation process has been discussed. (ias.ac.in)
  • the hydrogen-ion dependence has the form k obs = c+d [H + ]. The oxidation of [1, 1- 2 H 2 ] ethanol (MeCD 2 OH) exhibited a substantial primary kinetic isotope effect. (ias.ac.in)
  • The oxidation of deuterioformic acid showed the presence of a primary kinetic isotope effect ( k H / k D ≈4). (ias.ac.in)
  • The reaction exhibited the presence of a substantial kinetic isotope effect. (ias.ac.in)
  • 5. B.L. Silver and Z. Luz, The oxidation of diethylphosphonate, kinetics and kinetic isotope effect. (weizmann.ac.il)
  • Recently, we showed that growth of the macroalga Lobophora variegata on the fringing reefs of Curacao was co-limited by nitrogen and phosphorus 6 , indicating that elevated DIN and DIP concentrations potentially may have major effects on these ecosystems. (nature.com)
  • [3] [4] A recent synthesis of black phosphorus using metal salts as catalysts has been reported. (wikidoc.org)
  • Fig: 1(A) Structure of black phosphorus, (B) Synthesis methods of black phosphorus. (databasefootball.com)
  • Type D soils had a significantly higher & delta;N-15 in the organic layer and upper mineral soil than type C soils, which is likely due to N isotope fractionation by ectomycorrhizal fungi in the topsoil. (slu.se)
  • There is a reciprocal relationship between serum calcium and inorganic phosphorus. (cdc.gov)
  • We will also include the analysis of water isotopes (Delta o-18, Delta h-2) from the tile drain and soil water to coincide with the P-18O analysis. (usda.gov)
  • We were able to successfully develop this approach and we initiated analysis of subsurface drainage water samples and water extractable soil phosphorus during the spring of 2021. (usda.gov)
  • The water extractable soil phosphorus isotopic signature was consistent during the spring until the tile drains began to dry-out, varying by at most one per mil. (usda.gov)
  • As part of this research project, she seeks to identify how plants internally partition phosphorus amongst metabolic, lipid, nucleic acid and residual fractions, in regulating photosynthetic capacity and productivity across soil and landscape Phosphorus gradients. (edu.au)
  • Oxidation of lower phosphorus oxyacids by benzyltrimethylammonium dichloroiodate (BTACI), in the presence of zinc chloride, resulted in the formation of the corresponding oxyacids with phosphorus in a higher oxidation state. (ias.ac.in)
  • Four cations: Sodium, potassium, calcium, and magnesium Two accompanying anions: Chloride and phosphorus Daily requirements range from. (msdmanuals.com)
  • abstract = "Phosphorus levels correlate with atherosclerosis in both animal models and humans with advanced chronic kidney disease, but whether this relationship exists among individuals with normal kidney function is unknown. (manchester.ac.uk)
  • To measure these biochemical indicators in blood or urine, CDC's Environmental Health Laboratory (Division of Laboratory Sciences, National Center for Environmental Health) used a variety of analytical methods: isotope dilution tandem mass spectrometry, gas chromatography coupled to mass spectrometry, inductively coupled plasma mass spectrometry, atomic absorption spectroscopy, high performance liquid chromatography with different detection modes such as UV-visible and fluorescence, and various immuno-, protein binding, and colorimetric assays. (cdc.gov)
  • Determination of 3-quinuclidinyl benzilate (QNB) and its major metabolites in urine by isotope dilution gas chromatography/mass spectrometry. (cdc.gov)
  • Has 1 halo proton 32P is a radioactive isotope of phosphorus with relative atomic mass 31.973907 and half-life of 14.26 days. (wikipedia.org)
  • Phosphorus , ( Template:IPAEng , Template:Lang-el meaning "light", and phoros meaning "bearer"), is the chemical element that has the symbol P and atomic number 15. (wikidoc.org)
  • Isotopes are atomic species of the same chemical element (and therefore with the same atomic number (Z) or number of protons ) which differ with respect to their number of neutrons . (radiopaedia.org)
  • 4. Z. Luz and B.L. Silver, The acid catalyzed exchange of phosphorus bonded hydrogen in aqueous solutions of dialkyl phosphonates studied by nuclear magnetic resonances. (weizmann.ac.il)
  • periodic table]], phosphorus is never found as a pure element in nature, but only in combination with other elements. (citizendium.org)
  • IUPAC Periodic Table of the Elements and Isotopes (IPTEI) for the Education Community (IUPAC Technical Report). (radiopaedia.org)
  • Due to its high reactivity, phosphorus is never found as a free element in nature. (wikidoc.org)
  • Phosphorus magnetic resonance spectroscopy (31P-MRS) was used to study in vivo the energy metabolism of brain and skeletal muscle in two members of an Italian pedigree with NARP syndrome due to a point mutation at bp 8993 of mtDNA. (nih.gov)
  • Below is shown a chain of phosphorus atoms which exhibits both the purple and fibrous forms. (wikidoc.org)
  • Like graphene, BP has a single element layered structure consisting of phosphorus atoms (Fig: 1A). (databasefootball.com)
  • Phosphorus signifies an essential element in molecular biology, yet given the limited solubility of phosphates on early Earth, alternative sources like meteoritic phosphides have been proposed to incorporate phosphorus into biomolecules under prebiotic terrestrial conditions. (nature.com)
  • This is important, as is constitutes a reasonable level of uncertainty for phosphorus cycling studies which need to estimate bedrock δ18O‐PO4 composition based on the literature. (nerc.ac.uk)
  • Elemental phosphorus can exist in several allotropes , most commonly white, red and black. (wikidoc.org)
  • Elemental phosphorus is then liberated as a vapour and can be collected under phosphoric acid . (wikidoc.org)
  • The Thin Man gun-type design proved impractical to use with plutonium, and therefore a simpler gun-type called Little Boy was developed that used uranium-235, an isotope that makes up only 0.7 percent of natural uranium. (netlify.app)
  • In 1865 Hittorf discovered that when phosphorus was recrystallized from molten lead , a red/purple form is obtained. (wikidoc.org)
  • More recently, phosphine was attributed as the source of the phosphorus signal in comet 67P/Churyumov-Gerasimenko 16 . (nature.com)
  • However, it was suggested that a so-called specific difference between the hyperfine splittings in hydrogen-like and lithium-like ions of the same isotope can be used to cancel nuclear structure effects and provide an accurate test of QED [Shabaev et al. (fnal.gov)
  • 6. Z. Luz and B.L. Silver, NMR study of the exchange of phosphorus bonded hydrogen in dimethyl- and diethylphosphonate, catalyzed by acetate ion. (weizmann.ac.il)
  • The tile drain P-18O isotope signatures were close to equilibrium with precipitation Delta o-18 during the early water year. (usda.gov)
  • We will continue this analysis to more confidently assess impacts of tillage management on phosphorus export. (usda.gov)
  • The information derived from the P-18O signature of different pools will be highly complementary to the phosphorus export measurements in Objective 1a by potentially identifying different legacy phosphorus sources and quantifying P use efficiency. (usda.gov)
  • as such, phosphorus is considered a monoisotopic element. (wikipedia.org)
  • Phosphorus is a component of DNA and RNA and an essential element for all living cells . (wikidoc.org)
  • To see the isotopes that exist in the ScientificConstants package for a particular element, use the GetIsotopes function with the 'element' option specified. (maplesoft.com)
  • Therefore each isotope of an element has a different mass number (A), which is the simple summation of the number of protons and neutrons. (radiopaedia.org)
  • Follow the "Link to definition of property" or "Link to data for property" of the element phosphorus. (webelements.com)
  • They had a significantly lower atmospheric N deposition rate than type C soils, by a factor of 2.3, and a significantly higher phosphorus (P) concentration of the organic layer than type C soils, by a factor of 1.5. (slu.se)
  • The aim of this study was to identify the parameters that affect the nitrogen (N) isotope ratio (& delta;N-15) in soils of temperate and boreal forests. (slu.se)
  • It is proposed that the reactive oxidizing species is [PhCH 2 Me 3 N] + [Zn 2 Cl 6 ] −2 I + . It has been shown that the pentacoordinated tautomer of the phosphorus oxyacid is the reactive reductant. (ias.ac.in)
  • Prebiotic phosphorus chemistry could have been initiated by phosphorus (III) or the first organisms might have oxidized bioavailable phosphorus (III) to (V). Yet, the underlying synthetic routes to these phosphorus-bearing biomolecules along with their precursors are still in their infancy. (nature.com)
  • This fundamental knowledge on the origins of the phosphorus chemistry is critical to unravel how the phosphorus biochemistry and life itself might have emerged on early Earth. (nature.com)
  • One of the forms of red/black phosphorus is a cubic solid. (wikidoc.org)
  • Black phosphorus has an orthorhombic structure (C mca ) and is the least reactive allotrope, it consists of many six-membered rings which are interlinked. (wikidoc.org)
  • Black phosphorus is made of even larger aggregates and is the least reactive allotrope. (citizendium.org)
  • 2015). Among the three isotopes of phosphorus, a new 2D material known as black phosphorus (BP) has gained spectacular status in the scientific world recently, owing to its unique layered structure and layer-dependant properties. (databasefootball.com)