Pharmaceutical Vehicles
Suppression of experimental abdominal aortic aneurysms by systemic treatment with a hydroxamate-based matrix metalloproteinase inhibitor (RS 132908). (1/332)
BACKGROUND: Abdominal aortic aneurysms (AAAs) are associated with chronic inflammation, disruption of medial elastin, and increased local production of elastolytic matrix metalloproteinases (MMPs). The purpose of this study was to investigate how treatment with a hydroxamate-based MMP antagonist (RS 132908) might affect the development of experimental AAAs. METHODS: Male Wistar rats underwent intraluminal perfusion of the abdominal aorta with 50 units of porcine pancreatic elastase followed by treatment for 14 days with RS 132908 (100 mg/kg/day subcutaneously; n = 8) or with vehicle alone (n = 6). The external aortic diameter (AD) was measured in millimeters before elastase perfusion and at death, with AAA defined as an increase in AD (DeltaAD) of at least 100%. Aortic wall elastin and collagen concentrations were measured with assays for desmosine and hydroxyproline, and fixed aortic tissues were examined by light microscopy. RESULTS: AAAs developed in all vehicle-treated rats, with a mean AD (+/- SE) that increased from 1.60 +/- 0.03 mm before perfusion to 5.98 +/- 1.02 mm on day 14 (DeltaAD = 276.4 +/- 67.7%). AAAs developed in only five of eight animals (62.5%) after MMP inhibition, with a mean AD that increased from 1.56 +/- 0.05 mm to 3.59 +/- 0.34 mm (DeltaAD = 128.1 +/- 18.7%; P <.05, vs vehicle). The overall inhibition of aortic dilatation attributable to RS 132908 was 53.6 +/- 6.8%. Aortic wall desmosine fell by 85.4% in the vehicle-treated rats (1210.6 +/- 87.8 pmol/sample to 176.7 +/- 33.4 pmol/sample; P <.05) but only by 65.6% in the animals treated with RS 312908 (416.2 +/- 120.5 pmol/sample). In contrast, hydroxyproline was not significantly affected by either elastase perfusion or drug treatment. Microscopic examination revealed the preservation of pericellular elastin and a greater degree of fibrocollagenous wall thickening after MMP inhibition, with no detectable difference in the extent of inflammation. CONCLUSIONS: Systemic MMP inhibition suppresses aneurysmal dilatation in the elastase-induced rodent model of AAA. Consistent with its direct inhibitory effect on various MMPs, RS 132908 promotes the preservation of aortic elastin and appears to enhance a profibrotic response within the aortic wall. Hydroxamate-based MMP antagonists may therefore be useful in the development of pharmacologic approaches to the suppression of AAAs. (+info)Adventitial delivery minimizes the proinflammatory effects of adenoviral vectors. (2/332)
PURPOSE: Adenovirus-mediated arterial gene transfer is a promising tool in the study of vascular biology and the development of vascular gene therapy. However, intraluminal delivery of adenoviral vectors causes vascular inflammation and neointimal formation. Whether these complications could be avoided and gene transfer efficiency maintained by means of delivering adenoviral vectors via the adventitia was studied. METHODS: Replication-defective adenoviral vectors encoding a beta-galactosidase (beta-gal) gene (AdRSVnLacZ) or without a recombinant gene (AdNull) were infused into the lumen or the adventitia of rabbit carotid arteries. Two days after infusion of either AdRSVnLacZ (n = 8 adventitial, n = 8 luminal) or AdNull (n = 4 luminal), recombinant gene expression was quantitated by histochemistry (performed on tissue sections) and with a beta-gal activity assay (performed on vessel extracts). Inflammation caused by adenovirus infusion was assessed 14 days after infusion of either AdNull (n = 6) or vehicle (n = 6) into the carotid adventitia. Inflammation was assessed by means of examination of histologic sections for the presence of neointimal formation and infiltrating T cells and for the expression of markers of vascular cell activation (ICAM-1 and VCAM-1). To measure the systemic immune response to adventitial infusion of adenovirus, plasma samples (n = 3) were drawn 14 days after infusion of AdNull and assayed for neutralizing antibodies. RESULTS: Two days after luminal infusion of AdRSVnLacZ, approximately 30% of luminal endothelial cells expressed beta-gal. Similarly, 2 days after infusion of AdRSVnLacZ to the adventitia, approximately 30% of adventitial cells expressed beta-gal. beta-gal expression was present in the carotid adventitia, the internal jugular vein adventitia, and the vagus nerve perineurium. Elevated beta-gal activity (50- to 80-fold more than background; P <.05) was detected in extracts made from all AdRSVnLacZ-transduced arteries. The amount of recombinant protein expression per vessel did not differ significantly between vessels transduced via the adventitia (17.1 mU/mg total protein [range, 8.1 to 71.5]) and those transduced via a luminal approach (10.0 mU/mg total protein [range, 3.9 to 42.6]). Notably, adventitial delivery of AdNull did not cause neointimal formation. In addition, vascular inflammation in arteries transduced via the adventitia (ie, T-cell infiltrates and ICAM-1 expression) was confined to the adventitia, sparing both the intima and media. Antiadenoviral neutralizing antibodies were present in all rabbits after adventitial delivery of AdNull. CONCLUSION: Infusion of adenoviral vectors into the carotid artery adventitia achieves recombinant gene expression at a level equivalent to that achieved by means of intraluminal vector infusion. Because adventitial gene transfer can be performed by means of direct application during open surgical procedures, this technically simple procedure may be more clinically applicable than intraluminal delivery. Moreover, despite the generation of a systemic immune response, adventitial infusion had no detectable pathologic effects on the vascular intima or media. For these reasons, adventitial gene delivery may be a particularly useful experimental and clinical tool. (+info)Topical gene delivery to murine skin. (3/332)
We topically applied naked plasmid DNA containing the luciferase or chloramphenicol acetyltransferase cDNA directly to mouse skin. Gene expression was detected in skin samples as early as 4 h after DNA application, plateaued from 16 to 72 h post-application, and had decreased significantly by 7 d post-application. Reporter gene activity following topical DNA delivery was comparable with that produced by intradermal injection of DNA. Plasmid DNA at concentrations > or =0.25 microg per microl were required to achieve maximal expression levels. Reporter gene expression following topical administration was largely confined to the superficial layers of the epidermis and to hair follicles. Surprisingly, certain cationic liposomes inhibited the efficiency of cutaneous gene transfer. This technique provides a simple, clinically relevant approach to deliver genes to the skin, with potential application in treating a variety of cutaneous disorders. (+info)Inhibition of prostate cancer metastasis in vivo: a comparison of 1,23-dihydroxyvitamin D (calcitriol) and EB1089. (4/332)
The steroid hormone 1,25-dihydroxyvitamin D [1,25(OH)2D, also known as calcitriol] is known to inhibit the proliferation and to promote the differentiation of human prostate cancer cells. Additionally, we showed that 1,25(OH)2D markedly inhibits the invasiveness of human prostate cancer cells in vitro (G. G. Schwartz et al., Cancer Epidemiol. Biomark. Prev., 6: 727-732, 1997). These properties support the use of 1,25(OH)2D as differentiation therapy in prostate cancer. However, the use of 1,25(OH)2D in vivo is limited by the risk of hypercalcemia. We therefore compared the effects of 1,25(OH)2D and of EB1089, an analogue of 1,25(OH)2D with reduced calcemic effects, in an in vivo model of androgen-insensitive metastatic prostate cancer, the rat Dunning MAT LyLu prostate cancer model. Tumor growth and metastasis were studied using Copenhagen rats given s.c. injections of MAT LyLu cells. Fifty male rats were divided into five groups of 10 rats each. Four experimental groups received i.p. injections of low and high doses of 1,25(OH)2D and EB1089 (0.5 and 1.0 microg/kg, low and high, respectively). A control group received injections of vehicle only. Tumor volumes were measured three times per week. Rats were weighed weekly. The number of metastases to the lungs and the extent of hypercalcemia were evaluated. Compared with controls, tumor volumes were significantly smaller in all experimental groups. Similarly, the number of lung metastases (number of foci/lung) was reduced markedly by both 1,25(OH)2D and EB1089. Control rats developed 22.7 (+/- 1.98 SE) tumor foci per lung. Rats treated with 1,25(OH)2D and with EB1089 (1.0 microg/kg) developed 10.4 (+/- 2.81) and 7.70 (+/- 1.29) tumor foci, respectively (P < 0.001 and P < 0.0001, respectively; drug versus control). Compared with controls (10.79 +/- 0.1 mg/dl), serum calcium levels were significantly elevated in both 1,25(OH)2D and EB1089-treated rats (P < 0.01). However, EB1089 was significantly less calcemic than 1,25(OH)2D (12.59 +/- 0.21 mg/dl versus 14.47 +/- 0.46 mg/dl; 1.0 microg/kg; P < 0.001). Rats treated with 1,25(OH)2D showed marked weight loss: 20.0 +/- 1.9% and 26.3 +/- 1.7% of their initial weight (low and high doses, respectively, P < 0.001). Weight loss was significantly lower in rats treated with EB1089 at the high dose 8.4 (+/- 2.9) %. Moreover, rats treated with low-dose EB1089 gained 5.2 (+/- 3.7) % of their initial weight. In conclusion, 1,25(OH)2D and EB1089 showed marked and equivalent inhibition of prostate cancer metastasis in vivo. EB1089 was significantly less calcemic than 1,25(OH)2D and did not induce severe weight loss. This is the first report of a vitamin D analogue that significantly inhibits prostate cancer metastasis in vivo and that does so without producing cachexia or unacceptable hypercalcemia. (+info)Phase II trial of topically applied miltefosine solution in patients with skin-metastasized breast cancer. (5/332)
Skin deposits from breast cancer can present serious therapeutic problems, especially when resistant to conventional therapy. Topical application of a cytotoxic drug may represent an attractive new treatment modality devoid of major systemic toxicity. Miltefosine was selected because of its efficacy in breast cancer models. A mixture of alkylated glycerols of various chain lengths and water was used as the pharmaceutical vehicle to dissolve and to further facilitate tissue penetration of miltefosine. In our Institute a phase II study was performed to determine the efficacy and tolerability of topically applied miltefosine in patients with cutaneous metastases from breast cancer. Thirty-three patients in total entered the trial. A 6% miltefosine solution was applied once daily in the first week and twice daily in the following weeks. The planned minimum treatment duration was 8 weeks. We found an overall response rate of 43% for 30 evaluable patients, composed of 23% complete response and 20% partial response. The median response duration was 18 weeks, range 8-68. Toxicity consisted mainly of localized skin reactions, which could be controlled by a paraffin-based skin cream and, where appropriate, by dose modification. No systemic toxicities were observed. We conclude that topical miltefosine is an effective treatment modality in patients with skin metastases from breast cancer. (+info)Cremophor EL-mediated alteration of paclitaxel distribution in human blood: clinical pharmacokinetic implications. (6/332)
We have determined the in vitro and in vivo cellular distribution of the antineoplastic agent paclitaxel (Taxol) in human blood and the influence of Cremophor EL (CrEL), the vehicle used for i.v. drug administration. In the absence of CrEL, the blood:plasma concentration ratio was 1.07+/-0.004 (mean+/-SD). The addition of CrEL at concentrations corresponding to peak plasma levels achieved after the administration of paclitaxel (175 mg/m2 i.v. over a 3-h period; ie., 0.50%) resulted in a significant decrease in the concentration ratio (0.690+/-0.005; P < 0.05). Kinetic experiments revealed that this effect was caused by reduced erythrocyte uptake of paclitaxel by polyoxyethyleneglycerol triricinoleate, the major compound present in CrEL. Using equilibrium dialysis, it was shown that the affinity of paclitaxel for tested matrices was (in decreasing order) CrEL > plasma > human serum albumin, with CrEL present at or above the critical micellar concentration (approximately 0.01%). Our findings in the present study demonstrate a profound alteration of paclitaxel accumulation in erythrocytes caused by a trapping of the compound in CrEL micelles, thereby reducing the free drug fraction available for cellular partitioning. It is proposed that the nonlinearity of paclitaxel plasma disposition in patients reported previously should be reevaluated prospectively by measuring the free drug fractions and whole blood:plasma concentration ratios. (+info)Multisecond oscillations in firing rate in the basal ganglia: robust modulation by dopamine receptor activation and anesthesia. (7/332)
Multisecond oscillations in firing rate in the basal ganglia: robust modulation by dopamine receptor activation and anesthesia. Studies of CNS electrophysiology have suggested an important role for oscillatory neuronal activity in sensory perception, sensorimotor integration, and movement timing. In extracellular single-unit recording studies in awake, immobilized rats, we have found that many tonically active neurons in the entopeduncular nucleus (n = 15), globus pallidus (n = 31), and substantia nigra pars reticulata (n = 31) have slow oscillations in firing rate in the seconds-to-minutes range. Basal oscillation amplitude ranged up to +/-50% of the mean firing rate. Spectral analysis was performed on spike trains to determine whether these multisecond oscillations were significantly periodic. Significant activity in power spectra (in the 2- to 60-s range of periods) from basal spike trains was found for 56% of neurons in these three nuclei. Spectral peaks corresponded to oscillations with mean periods of approximately 30 s in each nucleus. Multisecond baseline oscillations were also found in 21% of substantia nigra dopaminergic neurons. The dopamine agonist apomorphine (0.32 mg/kg iv, n = 10-15) profoundly affected multisecond oscillations, increasing oscillatory frequency (means of spectral peak periods were reduced to approximately 15 s) and increasing the regularity of the oscillations. Apomorphine effects on oscillations in firing rate were more consistent from unit to unit than were its effects on mean firing rates in the entopeduncular nucleus and substantia nigra. Apomorphine modulation of multisecond periodic oscillations was reversed by either D1 or D2 antagonists and was mimicked by the combination of selective D1 (SKF 81297) and D2 (quinpirole) agonists. Seventeen percent of neurons had additional baseline periodic activity in a faster range (0.4-2.0 s) related to ventilation. Multisecond periodicities were rarely found in neurons in anesthetized rats (n = 29), suggesting that this phenomenon is sensitive to overall reductions in central activity. The data demonstrate significant structure in basal ganglia neuron spiking activity at unexpectedly long time scales, as well as a novel effect of dopamine on firing pattern in this slow temporal domain. The modulation of multisecond periodicities in firing rate by dopaminergic agonists suggests the involvement of these patterns in behaviors and cognitive processes that are affected by dopamine. Periodic firing rate oscillations in basal ganglia output nuclei should strongly affect the firing patterns of target neurons and are likely involved in coordinating neural activity responsible for motor sequences. Modulation of slow, periodic oscillations in firing rate may be an important mechanism by which dopamine influences motor and cognitive processes in normal and dysfunctional states. (+info)Predicting vehicle effects on the dermal absorption of halogenated methanes using physiologically based modeling. (8/332)
Occupational and environmental settings present opportunities for humans to come into contact with a variety of chemicals via the dermal route. The chemicals contacting the skin are likely to be diluted with a vehicle or present as a component of a mixture. In order to support risk assessment activities, we evaluated the vehicle effects on dermal penetration of two halogenated hydrocarbons, dibromomethane (DBM) and bromochloromethane (BCM). In vivo exposures to 15 combinations of of these in water, mineral oil, and corn oil vehicles were conducted, and blood was sampled for dibromomethane and bromochloromethane during the exposure at 0.5, 1, 2, 4, 8, 12, and 24 h. A physiologically based pharmacokinetic (PBPK) model was used to estimate the total amounts of dibromomethane or bromochloromethane that were absorbed during the exposure, and the dermal permeability coefficients were determined. While the permeability coefficients for dibromomethane and bromochloromethane were approximately 73- and 40-fold higher, respectively, in the water vehicle than in the corn oil, the permeability coefficient, when normalized for the skin:vehicle matrix partition coefficient, varied by less than a factor of 2. The permeability in an aqueous vehicle was then successfully used to predict the permeability coefficient for dibromomethane in a nonpolar vehicle, peanut oil. (+info)'Pharmaceutical vehicles,' also known as drug delivery systems, refer to various formulations or technologies that are designed to enhance the efficacy and safety of therapeutic agents by controlling their release, targeting them to specific sites in the body, improving their bioavailability, or prolonging their residence time at the site of action.
"Pharmaceutical vehicles" is not a standard term in medical or pharmaceutical sciences. However, I can provide some context based on the phrase's possible meaning. If by "pharmaceutical vehicles," you mean the carriers or delivery systems for drugs or medications, then the definition would be:
Pharmaceutical vehicles refer to various formulations, preparations, or technologies that facilitate and control the administration of a drug or therapeutic agent to its target site in the body. These can include different types of drug delivery systems such as tablets, capsules, liposomes, nanoparticles, transdermal patches, inhalers, injectables, and other innovative drug carrier technologies.
These pharmaceutical vehicles ensure that the active ingredients are safely and effectively transported to their intended site of action within the body, enhancing therapeutic efficacy while minimizing potential side effects.
'Motor vehicles' is a medical term that refers to self-propelled land transportation machines, which includes cars, trucks, buses, motorcycles, and other similar conveyances, capable of causing physical trauma or exacerbating medical conditions due to their mass, speed, and potential for collisions.
I'm sorry for any confusion, but "Motor Vehicles" is not a term that typically has a medical definition. It is a general term used to describe vehicles that are powered by a motor or engine and are designed for land transportation. This would include cars, trucks, motorcycles, buses, and other similar types of vehicles.
However, in a legal context, a "motor vehicle" may have a specific definition that varies by jurisdiction. For example, in some places, the definition might only include vehicles that are intended for use on public roads, excluding things like golf carts or construction equipment.
If you're looking for a medical term related to motor vehicles, there are many that could apply, such as "motor vehicle accident," "whiplash injury," or "traumatic brain injury due to motor vehicle collision." But the term "motor vehicles" itself does not have a specific medical definition.
Phagemid
"Pseudovirions as Vehicles for the Delivery of siRNA". Pharmaceutical Research. 27 (3): 400-420. doi:10.1007/s11095-009-0012-2. ...
Ufenamate
... or Delipidized Skin Using Different Vehicles". Biological & Pharmaceutical Bulletin. 38 (10): 1645-8. doi:10.1248/bpb.b15-00267 ...
Cell-penetrating peptide
Recently, several methods using CPPs as vehicles to deliver biologically active, full-length proteins into living cells and ... Pharmaceutical Research. 13 (9): 1367-72. doi:10.1023/a:1016026101195. PMID 8893276. S2CID 10646692. Herce HD, Garcia AE ( ... Stewart KM, Horton KL, Kelley SO (July 2008). "Cell-penetrating peptides as delivery vehicles for biology and medicine". ... Gariépy J, Kawamura K (January 2001). "Vectorial delivery of macromolecules into cells using peptide-based vehicles". Trends in ...
Bolivia-Germany relations
... vehicles and vehicle parts; chemical and pharmaceutical products; electrical goods and measurement; and control technology. ...
Namibia-United Kingdom relations
The UK's main export products to Namibia include: vehicles and cars; medicinal and pharmaceutical product; textile fabrics and ...
Ulm
The most important sector is still classical industry (machinery, especially motor vehicles; electronics; pharmaceuticals). The ... pharmaceuticals) Seeberger [de] (dried fruits, coffee, tea) Uzin Utz (construction materials) Walther Arms (fire arms, ...
Coup contrecoup injury
"A Review on Injury Mechanism of Intracerebral Hemorrhage in Vehicle Accidents". Current Pharmaceutical Design. 23 (15): 2177- ... Contrecoup, which may occur in shaken baby syndrome and vehicle accidents, can cause diffuse axonal injury. In some ...
Germany-New Zealand relations
Germany's main exports to New Zealand include: motor vehicles; mechanical machinery and equipment; pharmaceutical products and ...
Laupheim
Rentschler Holding GmbH: pharmaceutical products. Kässbohrer Geländefahrzeug: snow grooming vehicles. Diehl Aerospace: ... KG : manufacturer of machines for packaging of pharmaceutical products. ...
Dendrimer
Starpharma, an Australian pharmaceutical company, has multiple products that have either already been approved for use or are ... Dendrimers may also act as new ophthalmic vehicles for drug delivery, which are different from the polymers currently used for ... A study by Vanndamme and Bobeck used PAMAM dendrimers as ophthalmic delivery vehicles in rabbits for two model drugs and ... For dendrimers to be able to be used in pharmaceutical applications, they must surmount the required regulatory hurdles to ...
Industry in Argentina
In 2012[update] the leading sectors by volume were: food processing, beverages and tobacco products; motor vehicles and auto ... chemicals and pharmaceuticals); San Nicolás de los Arroyos (steel milling and metallurgy); and Ushuaia and Bahía Blanca (oil ... Next in importance are the Greater Buenos Aires area (food processing, metallurgy, motor vehicles and auto parts, chemicals and ... Córdoba is Argentina's major industrial center, hosting metalworking, motor vehicle and auto parts manufactures. ...
Argentina
... motor vehicles and auto parts; textiles and leather; refinery products and biodiesel; chemicals and pharmaceuticals; steel, ...
Economy of Argentina
This marked a peak in vehicle production, by 2021 production had fallen to 434,753 vehicles. Vehicles remain Argentina's top ... chemicals and pharmaceuticals; steel and aluminium; and industrial and farm machinery; electronics and home appliances. These ... Motor vehicles and auto parts are the leading industrial export, and over 12% of the total merchandise exports. Chemicals, ... In 2019, Argentina was the 31st world producer of steel, the 28th producer of vehicles, the 22nd world producer of beer, the ...
Dextran drug delivery systems
Huang, Shiyu; Huang, Gangliang (2019-07-01). "The dextrans as vehicles for gene and drug delivery". Future Medicinal Chemistry ... V. Degradation in human intestinal incubation models". European Journal of Pharmaceutical Sciences. 3 (6): 329-337. doi:10.1016 ... Pharmaceutical Development and Technology. 24 (8): 1032-1037. doi:10.1080/10837450.2019.1623252. ISSN 1083-7450. PMID 31159615 ...
Economy of Nigeria
produces armoured vehicles. Proforce sold an unknown number of armoured vehicles to Belarus in March 2022. This is the first ... Most larger pharmaceutical companies in Nigeria are located in Lagos. The pharmaceutical producer with the most employees in ... In Idah, Kogi State, Electric Motor Vehicle Company manufactures electrically powered vehicles. The company is owned by Prince ... "5 Advantages Of Driving An Innoson Vehicle". Innoson Vehicle Manufacturing. 18 December 2018. Retrieved 22 January 2020. ...
Nanoparticle drug delivery
Journal of Pharmaceutical Sciences, 2001. 90(6): p. 667-680. Malam, Y., M. Loizidou, and A.M. Seifalian, Liposomes and ... nanosized vehicles for drug delivery in cancer". Trends in Pharmacological Sciences. 30 (11): 592-599. doi:10.1016/j.tips. ... Pharmaceutical Research. 30 (2): 307-324. doi:10.1007/s11095-012-0889-z. ISSN 1573-904X. PMID 23073665. S2CID 18043667. Pawar, ... nanoparticles: nanosized vehicles for drug delivery in cancer. Trends in Pharmacological Sciences, 2009. 30(11): p. 592-599. ...
Xiangxue Pharmaceutical
Chen owned most of the stake in their investment vehicles. Part of the shares they owned were pledged (Chinese: 质押).: 78 Ms. ... Xiangxue Pharmaceutical Co., Ltd. also known as XPH, is a Chinese pharmaceutical company. It was headquartered in Guangzhou ... As of 31 December 2016 As of 31 December 2016 Charmacy Pharmaceutical (SEHK: 2289) Xiangxue Pharmaceutical was a sponsor of ... was owned by Xiangxue Pharmaceutical's competitor Guangzhou Pharmaceuticals from 2005 to 2009. Shenzhen F.C. II, the B team of ...
Veloxis Pharmaceuticals
MeltDose works by incorporating a drug substance with low water solubility into a "meltable" vehicle. It is then sprayed on an ... Veloxis Pharmaceuticals A/S, formerly LifeCycle Pharma A/S, develops improved versions of difficult-to-formulate drugs with its ... "About Veloxis Pharmaceuticals". www.envarsusxr.com. Retrieved 2023-03-01. "Home - Veloxis - Transplant Patients". Van Arnum P. ... Pharmaceutical Technology 35(7). "Home - Veloxis - Transplant Patients". Clinicaltrials.gov identifier: NCT01187953 Langone A, ...
ILC Dover
The I-suit is also being studied for use with next generation NASA launch vehicles and commercial space vehicles. ILC continues ... used to protect pharmaceutical workers from airborne active pharmaceutical ingredients (APIs). They also produce an air ... Over the following decade, ILC's production of LTA vehicles continued, and in 2001, ILC, in collaboration with TCOM and Uretek ... In the 1990s ILC entered the pharmaceutical industry with the design and production of flexible containment systems, used to ...
1960 New Year Honours
Alan Lace Mather, Chief Examiner of Motor Vehicles, Nyasaland. George Meikle, Assistant Chief Constable, Cyprus. David Martin ... Derek Evans Lovett, Superintending Pharmaceutical Chemist, Medical Department, Singapore. Mwase Lundazi, Senior Chief of the ... Albert Vincent Bannister, Senior Vehicle Examiner, Metropolitan Traffic Area, Ministry of Transport. Raymond Kingsley Barlow, ...
Excipient
Pharmaceutical regulations and standards require that all ingredients in drugs, as well as their chemical decomposition ... Such studies are called excipient-controlled or vehicle-controlled studies. Adjuvants are added to vaccines to enhance or ... Some typical preservatives used in pharmaceutical formulations are Antioxidants like vitamin A, vitamin E, vitamin C, retinyl ... Morin G, Briens L (September 2013). "The effect of lubricants on powder flowability for pharmaceutical application". AAPS ...
List of companies of the United Kingdom K-Z
Quantum Pharmaceutical - is a pharmaceuticals company producing and supplying unlicensed medicines, and special obtain products ... Smith Electric Vehicles - manufacturing company (electric trucks, trams, milk floats, ice-cream floats, fork lifts, taxis etc ... It was acquired by Takeda Pharmaceutical Company in 2018. SHS International - pharmaceuticals company (advanced medical ... Well Pharmacy - retail and pharmaceutical company (retail, pharmaceuticals, healthcare, and beauty products). Established in ...
Killorglin
Pharmaceutical firms Temmler and Astellas have small plants in Killorglin. It also has the operations centre for the Prize Bond ... The other three occupants remained trapped in the vehicle and drowned. Fexco, a major financial services company, was founded ...
Elkhart, Indiana
In 1934, the first recreational vehicle factory opened in Elkhart. Similar companies followed suit for the remainder of the ... pharmaceuticals, electronic components, manufactured housing and mobile homes. Numerous manufacturers of musical instruments ... Elkhart is home to many Recreational vehicle (RV) manufacturers, boat manufacturers, and van conversion companies, including ... Elkhart is best known for two industries: recreational vehicles and musical instruments (for example, Stephanhöuser Saxophones ...
India
The pharmaceutical industry in India emerged as a global player. As of 2021, with 3000 pharmaceutical companies and 10,500 ... In 2022, India became the world's third-largest vehicle market after China and the United States, surpassing Japan. At the end ... Biotechnology and Pharmaceutical Sector in India: sector briefing by the UK Trade and Investment 2011, utki.gov.uk Yep 2011. " ... "Isro-Saarc satellite to be a communication vehicle". Deccan Herald. DH News Service. 12 January 2015. Archived from the ...
Marah Lewis
Carrie then revealed that Maryanne's car went off a bridge and told the girls to find the vehicle. The girls figured out that ... Maryanne's father licensed the powder to Spaulding Pharmaceuticals. Carrie, who had described Maryanne as an innocent woman, ...
Canada-Italy relations
Italy's main exports to Canada include: Nuclear Reactors and machinery, beverages and vehicles (parts and motors). Italy is ... Canada's main exports to Italy include: Pharmaceutical products, cereals and mineral fuels. ...
Austria-Canada relations
Canada's main exports to Austria include: aircraft products, machinery and vehicles. Austria has an embassy in Ottawa. Canada ... Austria's main exports to Canada include: machinery and equipment, and pharmaceutical based products. ...
Humanitarian logistics
There are three main components: the number of trips for a vehicle, the volume, and the total number of vehicles. There are ... For example, hazardous materials must be stored separately from pharmaceutical products and food. The weight and volume of the ... In addition, they can read information when the vehicles pass through points along the route. After that, the information is ... They are attached to different types of vehicles, including pallets, trucks, vans, and large containers, to position the ...
Belgium-Canada relations
Belgian exports include fuels, diamonds and mineral oils, vehicles, machinery and pharmaceutical products. The same year Canada ...
Egypt-India relations
Mahindra are marketing their vehicles in Egypt, and Bajaj Auto dominated the three-wheelers market. Foreign relations of Egypt ... Ranbaxy has an Egyptian subsidiary for manufacturing pharmaceutical formulations; Ashok Leyland, Tata Motors, Maruti Suzuki and ...
Eloxx Pharmaceuticals Announces FDA Clearance to Begin Single Ascending Dose Study of ZKN-013
Trumps latest villain: Electric vehicles. Trump claims EVs are a hoax, even though Elon Musk became the worlds richest ... About Eloxx Pharmaceuticals. Eloxx Pharmaceuticals, Inc. is engaged in the science of ribosome modulation, leveraging its ... Eloxx Pharmaceuticals. ZKN-013 is in development for potential treatment of recessive dystrophic and junctional epidermolysis ... Eloxx Pharmaceuticals Announces FDA Clearance to Begin Single Ascending Dose Study of ZKN-013. ...
Pharmaceutical Robots Market worth $119.5 Million by 2021
Global pharmaceutical robots market for the forecast period of 2016 to 2021. This market is expected to reach USD 119.5 Million ... On-Highway and Off-Highway Vehicles. *. Advanced Technologies. *. Driving Support and Security. ... HOME › Press Releases › Pharmaceutical Robots Market worth $119.5 Million by 2021 Pharmaceutical Robots Market worth $119.5 ... The global pharmaceutical robots market is segmented on the basis of type, application, and region. ...
Actavis acquires Dutch pharmaceutical packing manufacturer | IceNews - Daily News
... of the shares of the Dutch pharmaceutical packing manufacturer PharmaPack International B.V., a specialist in packaging ... Iceland-based generic pharmaceuticals company, Actavis has recently acquired 100% ... Iceland-based generic pharmaceuticals company, Actavis has recently acquired 100% of the shares of the Dutch pharmaceutical ... Actavis acquires Dutch pharmaceutical packing manufacturer. Business, General, Holland, Iceland, International Zoom Out Zoom In ...
World's Most Admired Companies 2011: Industries - Pharmaceuticals - FORTUNE on CNNMoney.com
PHARMACEUTICAL TRANSPORT VEHICLES - Superior Products Europe
Drug Delivery Vehicles - Broome Theranostics & Pharmaceutical Engineering
We have created a micellar device, both Targeted (TRaM) and untargeted (RaM), at a size conducive to therapeutic delivery and cellular uptake. Tracking fluorophores allow us to detect and monitor the delivery. Focused delivery is achieved by decorating the nanoparticle with various targeting molecules. Local rupture of the device allowing for delivery of the payload has been programmed into the device such that release of a particular therapy is dependent on the environment specific to the transplanted organ. Promising proof-of-concept suggest that these devices improve the patients ability to maintain tolerance to and keep their organs without causing immunosuppression over their entire immune system ...
RFID Improves Pharmaceutical Supply Chain Efficiency and Patient Safety - RFID JOURNAL
How to Track Vehicles. RFID Journal LIVE! 2023 will feature end-user companies discussing RFIDs use in various industries, ... ... May 23, 2022Pharmaceutical traceability across the global supply chain is increasingly essential to enhance brand protection ... FASTag RFID System Serves 97 Percent of Indian Vehicles. India has the worlds largest population, with approximately 26 ... RFID Improves Pharmaceutical Supply Chain Efficiency and Patient Safety. By Mark Roberti ...
A vehicle rams into a victory celebration for Liberia's president-elect, killing 3 and injuring 17 | WREG.com
A speeding vehicle rammed into jubilant supporters of President-elect Joseph Boakai at a victory celebration, killing at least ... Pharmaceutical company AbbVie buying ImmunoGen in … Global leaders pay tribute to Henry Kissinger, but … ... A vehicle rams into a victory celebration for Liberias president-elect, killing 3 and injuring 17 by: MARK M. MENGONFIA, ... MONROVIA, Liberia (AP) - A speeding vehicle rammed into jubilant supporters of President-elect Joseph Boakai at a victory ...
BYD (China), Tesla (US) and Volkswagen AG (Germany) are leading players in Electric Vehicle Market
Get known & unknown adjacencies impacting the market for Electric Vehicle Market. ... The research insight on Electric Vehicle Market industry highlights the prominent players in the market. ... Electric Vehicle Market by Component, Vehicle Type, Vehicle Class, Propulsion (BEV, PHEV, FCEV), Vehicle Drive Type (FWD, RWD, ... Pharmaceutical IT. * Provider IT. * Analytical and Scientific Instrumentation *. Building & Construction *. Building & ...
Twitter Threatened With Class-Action Lawsuit for Banning Doctor Over COVID-19 Vaccine Post - The Epoch Times
Millennium Partners, L.P. UK Regulatory Announcement: Form 8.3 - Dechra Pharmaceuticals plc | Business Wire
Phagemid - Wikipedia
Chitosan: a unique polysaccharide for drug delivery
The aim of this review is to give an insight into the many potential applications of chitosan as a pharmaceutical drug carrier ... The aim of this review is to give an insight into the many potential applications of chitosan as a pharmaceutical drug carrier ... and as a vehicle for parenteral drug delivery devices. The use of chitosan to manufacture sustained-release systems deliverable ...
Tesla, Delta rise; Acadia Pharmaceuticals, Occidental fall - The San Diego Union-Tribune
Police say about five people were struck by a vehicle while picketing in the United Auto Workers strike outside a Flint-area ... Acadia Pharmaceuticals Inc., down $4.41 to $21.18.. The FDA declined approval of the biopharmaceutical companys drug ... The electric car maker delivered nearly 185,000 vehicles in the first quarter, beating Wall Street forecasts. ... 5 workers picketing in UAW strike hit by vehicle outside Flint-area plant ...
Phase I Study Results for Qilu Pharmaceutical's Iparomlimab (QL1604) Now Published - Thailand Business News
Thailand gears up to make a significant impact in the zero-emission vehicles (ZEV) sector 13 shares Share 5 Tweet 3 ... Thailand gears up to make a significant impact in the zero-emission vehicles (ZEV) sector 13 shares Share 5 Tweet 3 ... Phase I Study Results for Qilu Pharmaceuticals Iparomlimab (QL1604) Now Published. by PR Newswire ... QL1604 is an innovative monoclonal antibody drug developed by Qilu Pharmaceutical. The findings of the study demonstrated that ...
Electric vehicles a $300 million opportunity for Tata AutoComp - The Economic Times
The Tata Group company is forming a division within the company for electric vehicles and it will be headed by AK Jindal, who ... Sun Pharmaceutical Industries. Share Price. 1231.15. 03:59 PM , 04 Dec 2023. -0.10(0.00%). ... The Tata Group company is forming a division within the company for electric vehicles and it will be headed by AK Jindal, who ... Tata Motors electric sport-utility vehicle (SUV) Nexon EV.. NEW DELHI: Tata AutoComp plans to invest more than Rs 500 crore to ...
New vehicles from Detroit's automakers are planned in contracts that ended UAW strikes | News 4 Buffalo
Ram and Dodge vehicles. Ford envisions at least three new electric vehicles that will preserve jobs at several factories. ... General Motors plans to build at least six new electric vehicles, including a full-size SUV. Those and […] ... Pharmaceutical company AbbVie buying ImmunoGen in … Global leaders pay tribute to Henry Kissinger, but … ... New vehicles from Detroits automakers are planned in contracts that ended UAW strikes by: TOM KRISHER and ALEX VEIGA, ...
EV shock survey: 55% reject vehicles over price & fear | KTSM 9 News
Our Auto Expert) - The transition to electric vehicles (EVs) in America has been more gradual than expected, a trend ... Pharmaceutical company AbbVie buying ImmunoGen in … Global leaders pay tribute to Henry Kissinger, but … ... Our Auto Expert) - The transition to electric vehicles (EVs) in America has been more gradual than expected, a trend ... EV shock survey: 55% reject vehicles over price & fear by: Nik Miles, Our Auto Expert ...
Investment Climate Statements: Custom Report Excerpts - United States Department of State
... retail of finished pharmaceutical products; and the production, supply, and retail of drinking water in sealed pouches. Sectors ... and complete-knocked down vehicles (0 percent for ten years). Tax rebates are also offered in the form of incentives based on ... and counterfeit pharmaceuticals have found their way into public hospitals. Counterfeit products have also been discovered in ... the operation of taxi and car rental services with fleets of fewer than 25 vehicles; lotteries (excluding soccer pools); the ...
HINDUSTAN HYDRO CHEMICALS & PHARMACEUTICALS PVT. LTD. Franchise Opportunity - Franchise India
PHARMACEUTICALS PVT. LTD. franchise. Get the HINDUSTAN HYDRO CHEMICALS & PHARMACEUTICALS PVT. LTD. franchising information ... Join HINDUSTAN HYDRO CHEMICALS & PHARMACEUTICALS PVT. LTD. franchise and be on your way to owning and running a successful ... 500kg to 700 kg goods transporting capacity vehicle for material distribution or at the initial stage of your business you can ... HINDUSTAN HYDRO CHEMICALS & PHARMACEUTICALS PVT. LTD. Expansion Plans. North. Haryana, Himachal Pradesh, Jammu and Kashmir, ...
Enabling Discovery Through Leveraging and Miniaturizing Pharmaceutical Principles and Processes | SpringerLink
Drummond C, Fong C (2000) Surfactant self assembly objects as novel drug delivery vehicles. Curr Opin Colloid Interface Sci 4: ... American Association of Pharmaceutical Scientists Northeast Regional Discussion Group annual conference, Rocky Hill, CT, 19 Apr ... Enabling Discovery Through Leveraging and Miniaturizing Pharmaceutical Principles and Processes. *Roy J. Haskell. 7, ... Babcock C, Friesen T et al (2009) Method and device for evaluation of pharmaceutical compositions. US Patent 7611630 B2, 3 Nov ...
Punjab approves 50pc provision of subsidy on electric vehicles - Daily Times
Pakistan highlights pharmaceutical collaboration with SCO countries. PSX gains 87.38 points. More Posts from this Category ... The CM apprised that 50 percent subsidy will be provided to the electric vehicles in respect of taxes. Approval was granted to ... The provincial cabinet also granted approval to the formulate regulations for the registration of electric vehicles. It was ...
Investment Climate Statements: Custom Report Excerpts - United States Department of State
... retail of finished pharmaceutical products; and the production, supply, and retail of drinking water in sealed pouches. Sectors ... the operation of taxi and car rental services with fleets of fewer than 25 vehicles; lotteries (excluding soccer pools); the ... and counterfeit pharmaceuticals have found their way into public hospitals. Counterfeit products have also been discovered in ...
Abstracts - FIP - International Pharmaceutical Federation
Preparation and evaluation of starch citrate - a new modified starch as directly compressible vehicle ... Early Career Pharmaceutical Group back Early Career Pharmaceutical Group * About the Early Career Pharmaceutical Group ... Board of Pharmaceutical Practice back Board of Pharmaceutical Practice * Board of Pharmaceutical Practice ... Board of Pharmaceutical Sciences back Board of Pharmaceutical Sciences * Board of Pharmaceutical Sciences ...
Ty Warner got off easy
Customs puts a stop to the clearing of pharmaceuticals, old vehicles at Tin Can port - Eve Afrique
... has barred importers and agents from clearing pharmaceutical products and overage used vehicles imported through the Tin Can ... Customs puts a stop to the clearing of pharmaceuticals, old vehicles at Tin Can port. ... has barred importers and agents from clearing pharmaceutical products and overage used vehicles imported through the Tin Can ... A circular has been passed stating that pharmaceuticals would not be allowed at Tin Can Island Port. It is an extant law that ...
Pharmaceutical Equipment Plant Gets $5M Upgrade | ASSEMBLY
MN-A manufacturer of mixing and storage equipment for the pharmaceutical industry has completed a $5 million expansion of its ... Does your factory use automated guided vehicles or autonomous mobile robots?. Yes. ... BLOOMINGTON, MN-A manufacturer of mixing and storage equipment for the pharmaceutical industry has completed a $5 million ...
56 Biggest Movers From Friday - AlloVir (NASDAQ:ALVR), Ampio Pharmaceuticals (AMEX:AMPE) - Benzinga
Cyngn recently announced the official launch of DriveMod Kit, a turnkey autonomous vehicle solution. ... Ampio Pharmaceuticals, Inc. AMPE rose 13.6% to close at $0.2815. Ampio Pharmaceuticals shares dropped 27% on Thursday after the ... Vallon Pharmaceuticals, Inc. VLON shares jumped 100.9% to close at $2.27 on Friday. Vallon Pharmaceuticals engaged Ladenburg ... Salarius Pharmaceuticals, Inc. SLRX dropped 20.5% to close at $0.2701 after the company announced a $2.3 million registered ...
Putting the Patient at the Center of the Pharmaceutical Supply Chain | Supply & Demand Chain Executive
... the pharmaceutical supply chain needs special care and attention. The patient relies on medication for healing and recovery, ... Women in Supply Chain: ISEEs Co-Founder, Debbie Yu, to Revolutionize Logistics with Autonomous Vehicles. ISEEs co-founder, ... Putting the Patient at the Center of the Pharmaceutical Supply Chain. With so much at stake, the pharmaceutical supply chain ... The pharmaceutical industry is also recognizing that, if they intend to create medications that improve or extend the lives of ...
Blockchain For Social Good2023DrugsAutonomousTransition to electric vehiclesCompaniesIndiaContainersProcessesSectorsElectric and hybrid vehiclesPassengerStrategicBLOOMINGTONManufacturingIndustryProductsCompanyPracticeJoint ventureRobotsModulationManufactureEvolutionOralPatentViableApprovalSupplyPartsMillionDrugPercentGlobalEquipmentMarketPersonalDataProductionIndustrialBusinessResearchCommercialPatientsServices
20231
- JINAN, China , Nov. 6, 2023 /PRNewswire/ - Recently, the results of the Phase I study for iparomlimab (R&D code: QL1604), developed by Qilu Pharmaceutical Co., Ltd. were published online in the academic journal Frontiers in Immunology (2022 Impact Factor: 7.3). (thailand-business-news.com)
Drugs7
- On the basis of application, the global pharmaceutical robots market is segmented into picking and packaging, inspection of pharmaceutical drugs, and laboratory applications. (marketsandmarkets.com)
- Revealing blockchain's potential to eliminate counterfeit drugs from the pharmaceutical supply chain. (accenture.com)
- A greater understanding of the physical processes involved in the release of drugs from polymeric vehicles is essential for the design of new controlled release devices. (nottingham.ac.uk)
- products are used as Active Pharmaceutical Ingredients (APIs) in drugs for treatment of chronic constipation, and as an intestinal lavage to facilitate bowel cleansing prior to medical procedures such as colonoscopies, radiological exams or gastrointestinal surgery. (manufacturing.net)
- Concordance of motor vehicle crash, emergency department, and inpatient hospitalization data sets in the identification of drugs in injured drivers. (cdc.gov)
- The purpose of the present study was to link crash data with emergency department (ED) and inpatient hospitalization data to assess the concordance between the data sets in the identification of the presence of drugs among injured motor vehicle drivers (passenger cars, passenger trucks, light trucks, and semi-trucks) in Kentucky. (cdc.gov)
- CONCLUSIONS: Surveillance data from multiple public health data sets is necessary to identify the presence of drugs in injured drivers involved in motor vehicle crashes. (cdc.gov)
Autonomous2
- Does your factory use automated guided vehicles or autonomous mobile robots? (assemblymag.com)
- Cyngn recently announced the official launch of DriveMod Kit, a turnkey autonomous vehicle solution. (benzinga.com)
Transition to electric vehicles2
- The automakers have all embraced the transition to electric vehicles as a large-scale and long-term commitment. (wivb.com)
- Our Auto Expert) - The transition to electric vehicles (EVs) in America has been more gradual than expected, a trend illuminated by recent findings from an Auto Pacific survey. (ktsm.com)
Companies13
- Factors such as the increase in domestic industrial robot companies, flourishing pharmaceutical industry, increasing number of conferences and exhibitions, investment and funding in the robots industry, and Japan s Robot Strategy are driving the growth of the APAC pharmaceutical robots market. (marketsandmarkets.com)
- The naming of nominee or vehicle companies is insufficient. (businesswire.com)
- Ill. In each new contract between the United Auto Workers union and General Motors, Ford and Stellantis, parts of the companies' secret long-term plans for new vehicles are exposed. (wivb.com)
- The UAW's success in gaining commitments from the companies to build new electric vehicles at several factories represented a particular achievement. (wivb.com)
- Pharmaceutical companies must focus on delivering products better to provide meaningful and impactful experiences, according to Guy Yeoman, Vice President of Patient Centricity at AstraZeneca. (sdcexec.com)
- Providers and pharmaceutical companies need to work with patients to develop solutions that are mutually agreeable. (sdcexec.com)
- Enhanced communications among patients, advocacy groups, and pharmaceutical companies, allowing their voices to be heard. (sdcexec.com)
- Gone are the days of pharmaceutical companies choosing what's best for the patient. (sdcexec.com)
- Pharmaceuticals companies must balance commercial realities and shareholder expectations with work environments that respect individuals' personal objectives and desires to make a difference, the study says. (industryweek.com)
- The study anticipates an industry split into two basic organizational models -- superpharma (huge pharmaceuticals companies) and supernets (networked arrangements including strategic alliances, joint ventures, and outsourcing) -- both requiring very different management styles from the current norm. (industryweek.com)
- Using the beamlines and tools at MAX IV, researchers from drug discovery companies find brand new starting points for developing novel pharmaceutical substances. (lu.se)
- China is making considerable advances in vaccine production, working with established pharmaceutical companies in a joint venture approach or by developing and manufacturing vaccines locally. (cdc.gov)
- Our cases highlight the need to obtain satisfactory cooperation from pharmaceutical companies involved in the manufacture of these widely used medical devices. (lu.se)
India1
- One of the Dutch company's future roles will be the bulk packaging of pharmaceuticals produced in the Actavis facility in Alathur (India). (icenews.is)
Containers1
- So is counting and packaging pills into containers in pharmaceutical firms. (worldbank.org)
Processes1
- Another driver is regulatory agencies, which have taken measures to include the patient in the development and approval processes for pharmaceuticals. (sdcexec.com)
Sectors1
- Not surprisingly, the production of vehicles that run on gas also features highly on the list of top sectors. (cbsnews.com)
Electric and hybrid vehicles1
- It offers a wide range of electric and hybrid vehicles and sells majorly in the Chinese market. (marketsandmarkets.com)
Passenger2
- Building rideshare passenger trust by using a blockchain-based digital identity to match drivers to vehicles. (accenture.com)
- The Chicago Transit Authority is leveraging IoT technology in an innovative passenger-counting project to gather vehicle occupancy data, increase rider comfort, and improve the passenger experience. (digi.com)
Strategic2
- Vallon Pharmaceuticals engaged Ladenburg Thalmann & Co Inc to evaluate strategic alternatives for the Company to maximize shareholder value. (benzinga.com)
- Vehicle electrification is upending the automotive landscape, forcing suppliers to make critical strategic and operational decisions. (industryweek.com)
BLOOMINGTON1
- BLOOMINGTON, MN-A manufacturer of mixing and storage equipment for the pharmaceutical industry has completed a $5 million expansion of its assembly plant here. (assemblymag.com)
Manufacturing3
- The key factor driving the growth of the market is the benefits offered by robotic systems in pharmaceutical manufacturing. (marketsandmarkets.com)
- Factors such as demand for personalized packaging configurations and advantages of robots in pharmaceutical manufacturing such as high speed, accuracy, ability to track and trace, error-free operation, fewer accidents, and better utilization of the floor space are contributing to the large share of the picking and packaging segment. (marketsandmarkets.com)
- TAIYOL LUBRICANTS is the registered trademark & brand of Hindustan Hydro Chemicals & Pharmaceuticals Private Limited (HHCP PL), incorporated in 2015 engaged in manufacturing & distribution of premium quality petrochemical products i.e. (franchiseindia.com)
Industry5
- The pharmaceutical industry is also recognizing that, if they intend to create medications that improve or extend the lives of patients, then patients should have a say in how those medications are delivered. (sdcexec.com)
- In car industry, for example, there is almost no demand anymore for routine manual tasks, such as installing windshields on new vehicles. (worldbank.org)
- PEGs to the pharmaceutical industry across 27 European Union countries. (manufacturing.net)
- products are specialty ingredients and process aids produced specifically to meet the requirements of the pharmaceutical, personal care, and other industries that are subject to customer, industry or governmental standards for purity. (manufacturing.net)
- PEGs are frequently used as processing aids in the pharmaceutical industry when particle size uniformity or fine concentration is desired in the granulation process. (manufacturing.net)
Products4
- Iceland-based generic pharmaceuticals company , Actavis has recently acquired 100% of the shares of the Dutch pharmaceutical packing manufacturer PharmaPack International B.V., a specialist in packaging pharmaceutical and biotechnological products. (icenews.is)
- The Tin Can Island Command of the Nigeria Customs Service (NCS) has barred importers and agents from clearing pharmaceutical products and overage used vehicles imported through the Tin Can Island Port Complex. (eveafrique.com)
- The World Health Organisation's International Medical Products Anti-Counterfeiting Taskforce (IMPACT) estimates that fake pharmaceuticals - medicines produced by unlicensed manufacturers and introduced directly into the global supply chain -make up one per cent of drug sales in developed countries and approximately 30 per cent in some countries in Asia, Africa and Latin America. (khaleejtimes.com)
- These sorts of products have been associated with pharmaceutical liability lawsuits across the country. (rochongenova.com)
Company6
- For further information regarding this acquisition, alongside details about the generic pharmaceuticals company, visit www.actavis.com/en . (icenews.is)
- BYD Auto operates as a subsidiary of BYD Company and is majorly involved in the electric vehicle, battery, and electric charging business. (marketsandmarkets.com)
- The Tata Group company is forming a division within the company for electric vehicles and it will be headed by AK Jindal, who was earlier heading R&D at Tata Motors. (indiatimes.com)
- Ampio Pharmaceuticals shares dropped 27% on Thursday after the company provided a regulatory update and said the FDA did not agree with the company's proposed changes to its AP-013 trial. (benzinga.com)
- At an open forum attended by representatives of the Ministry of Health and private sector on Thursday in Sharjah, a representative pharmaceutical company Pfizer, said there is still a threat in the Middle East despite recent initiatives to curb illicit trade in fake - and potentially harmful - medicines. (khaleejtimes.com)
- Dow Polyglycols, Surfactants and Fluids (PS&F), a business unit of The Dow Chemical Company, today announced that Univar has been named Pan- European distributor of CARBOWAX™ SENTRY™ pharmaceutical grade polyethylene glycols (PEGs). (manufacturing.net)
Practice2
- The chair of the new national committee and the CEO of Medical Practice and Licence at the Ministry of Health, Dr. Amin Al Amiri, said the committee will extend its reach beyond the pharmaceuticals used to treat chronic conditions like diabetes, hypertension and cardiovascular diseases preferred by counterfeiters to medical devices and food supplements. (khaleejtimes.com)
- Additionally, our firm is well-equipped to represent groups of people suffering due to the same medical device or drug through our pharmaceutical class actions practice center. (findlaw.com)
Joint venture1
- Last month, Tata AutoComp entered into a 50:50 joint venture with Prestolite Electric , China's second largest electric vehicle motor manufacturer, for local production of starter, motor and alternators. (indiatimes.com)
Robots5
- This report studies the global pharmaceutical robots market for the forecast period of 2016 to 2021. (marketsandmarkets.com)
- The global pharmaceutical robots market is segmented on the basis of type, application, and region. (marketsandmarkets.com)
- The articulated robots segment accounted for the largest share of the global pharmaceutical traditional robots market in 2016. (marketsandmarkets.com)
- In 2016, the picking and packaging segment accounted for the largest share of the global pharmaceutical robots market. (marketsandmarkets.com)
- Based on region, the pharmaceutical robots market is divided into North America, Europe, Asia-Pacific, and the Rest of the World. (marketsandmarkets.com)
Modulation1
- Eloxx Pharmaceuticals, Inc. is engaged in the science of ribosome modulation, leveraging its innovative TURBO-ZM™ chemistry technology platform in an effort to develop novel Ribosome Modulating Agents (RMAs) and its library of Eukaryotic Ribosome Selective Glycosides (ERSGs). (yahoo.com)
Manufacture1
- Many of the plans will continue the manufacture of vehicles that the automakers already build. (wivb.com)
Evolution1
- My work in this area focuses on using MFX imaging and NMR (PGSE and DOSY) techniques to study the drug spatial distribution and structural evolution within polymeric vehicles during the drug release process. (nottingham.ac.uk)
Oral1
- The first part of this review concerns the principal uses of chitosan as an excipient in oral formulations (particularly as a direct tableting agent) and as a vehicle for parenteral drug delivery devices. (nih.gov)
Patent1
- A patent analysis and discussion of power sources and vehicle components describes the areas in which research is being performed and emphasizes intellectual property issues. (bccresearch.com)
Viable1
- With rising environmental awareness and stringent regulations, consumers and businesses are increasingly embracing EVs as a viable alternative to conventional internal combustion engine vehicles. (marketsandmarkets.com)
Approval1
- The provincial cabinet also granted approval to the formulate regulations for the registration of electric vehicles. (com.pk)
Supply5
- May 23, 2022 Pharmaceutical traceability across the global supply chain is increasingly essential to enhance brand protection and anti-counterfeiting, improve loss prevention and patient safety. (rfidjournal.com)
- Right now, we are at a starting point, but as the segment evolves, we will be able to supply almost 60% content of an electric vehicle," said Goel. (indiatimes.com)
- With so much at stake, the pharmaceutical supply chain needs special care and attention. (sdcexec.com)
- This puts a lot of weight and responsibility on the pharmaceutical supply chain. (sdcexec.com)
- There are a number of factors that contribute to this new demand for patient-focused pharmaceutical supply chains. (sdcexec.com)
Parts1
- Tata AutoComp plans to invest more than Rs 500 crore to set up new plants and localise electric vehicle parts, as momentum in favour of cleaner vehicles gathers speed. (indiatimes.com)
Million1
- Note that values are expressed in million dollars and shipments are expressed in 1,000 vehicles. (bccresearch.com)
Drug3
- The aim of this review is to give an insight into the many potential applications of chitosan as a pharmaceutical drug carrier. (nih.gov)
- QL1604 is an innovative monoclonal antibody drug developed by Qilu Pharmaceutical. (thailand-business-news.com)
- The U.S. Food and Drug Administration (FDA) and the European Medicines Agency (EMA) are both working to include patient opinions in pharmaceutical development, including measures like holding meetings with patient groups. (sdcexec.com)
Percent1
- The CM apprised that 50 percent subsidy will be provided to the electric vehicles in respect of taxes. (com.pk)
Global2
- The global electric vehicles market reached $94.9 billion in 2019 and should reach $183.7 billion by 2024, at a compound annual growth rate (CAGR) of 14.1% for the period of 2019-2024. (bccresearch.com)
- In a prior phase 2a study , TMB-001 0.1% and 0.2% ointment twice a day demonstrated greater improvement in ≥ 1 and ≥ 2 Investigator Global Assessment (IGA) scores compared with vehicle. (medscape.com)
Equipment1
- Niche vehicles (self-driving vehicles, military equipment, locomotives). (bccresearch.com)
Market1
- The electric vehicle (EV) market has witnessed unprecedented growth in recent years, signaling a remarkable shift towards cleaner and more sustainable transportation solutions worldwide. (marketsandmarkets.com)
Personal1
- Low-velocity vehicles (golf carts, neighborhood EVs, personal mobility devices). (bccresearch.com)
Data2
- In addition, technologies like advanced analytics and artificial intelligence are allowing for evaluation of data sets that can improve pharmaceutical design. (sdcexec.com)
- The use of a single surveillance data set alone may significantly underreport the number of drugged drivers who were injured in a motor vehicle collision. (cdc.gov)
Production1
- But the production of some new vehicles over the next few years is being planned, too. (wivb.com)
Industrial1
- EXPOSURES POSE A REAL industrial and vehicle emissions, molds and other microbes, pharmaceuticals, THREAT TO THEIR HEALTH. (cdc.gov)
Business2
- Managing director Arvind Goel said Tata AutoComp would invest over Rs 1,000 crore in the coming two to three years and more than 50% of this would be in the electric vehicle business. (indiatimes.com)
- Country cases: Different business models which have adopted and integrated pharmaceutical services. (fip.org)
Research1
- Pharmaceutical Research. (wikipedia.org)
Commercial1
- For the purpose of this report, the term "electric vehicles" includes commercial approaches such as pure battery-powered, plug-in hybrid, hybrid internal combustion/battery, range extended, and FCVs, as well as vehicles powered by developmental power sources such as supercapacitors and flywheel. (bccresearch.com)
Patients4
- For the current trial, 33 patients 9 years of age and older with genetically confirmed XLRI/ARCI-LI and ≥ 2 (out of 4) Visual Index for Ichthyosis Severity (VIIS) assessment areas with a ≥ 3 scaling score were randomized 1:1:1 to TMB-001 0.05%, TMB-001 0.1%, or vehicle twice daily for 12 weeks. (medscape.com)
- Of the 33 patients, 11 patients received TMB-001 0.05%, 10 received TMB-001 0.1%, and 12 received the vehicle. (medscape.com)
- An improvement of a ≥ 2-grade IGA score was observed in 100%, 50%, and 25% of patients with XLRI and 100%, 67%, and none of the patients with ARCI-LI who received TMB-001 0.05%, TMB-001 0.1%, and vehicle, respectively. (medscape.com)
- Method: Four patients with eczematous skin eruptions after using OmniPod, including 2 with previous adverse skin reactions to FreeStyle Libre, were patch tested with a baseline series and additional (meth)acrylates, including IBOA in several concentrations and/or vehicles. (lu.se)
Services1
- En termes de prestations de services, les problèmes posés par les personnes déplacées, leur dispersion géographique et leurs déplacements par étapes ont été gérés grâce à une stratégie de riposte sanitaire couronnée de succès, comprenant treize interventions principales et un ensemble de directives standard de mise en oeuvre sur le terrain. (who.int)
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