The lateral of the two terminal branches of the sciatic nerve. The peroneal (or fibular) nerve provides motor and sensory innervation to parts of the leg and foot.
Disease involving the common PERONEAL NERVE or its branches, the deep and superficial peroneal nerves. Lesions of the deep peroneal nerve are associated with PARALYSIS of dorsiflexion of the ankle and toes and loss of sensation from the web space between the first and second toe. Lesions of the superficial peroneal nerve result in weakness or paralysis of the peroneal muscles (which evert the foot) and loss of sensation over the dorsal and lateral surface of the leg. Traumatic injury to the common peroneal nerve near the head of the FIBULA is a relatively common cause of this condition. (From Joynt, Clinical Neurology, 1995, Ch51, p31)
The medial terminal branch of the sciatic nerve. The tibial nerve fibers originate in lumbar and sacral spinal segments (L4 to S2). They supply motor and sensory innervation to parts of the calf and foot.
A branch of the tibial nerve which supplies sensory innervation to parts of the lower leg and foot.
The nerves outside of the brain and spinal cord, including the autonomic, cranial, and spinal nerves. Peripheral nerves contain non-neuronal cells and connective tissue as well as axons. The connective tissue layers include, from the outside to the inside, the epineurium, the perineurium, and the endoneurium.
A nerve which originates in the lumbar and sacral spinal cord (L4 to S3) and supplies motor and sensory innervation to the lower extremity. The sciatic nerve, which is the main continuation of the sacral plexus, is the largest nerve in the body. It has two major branches, the TIBIAL NERVE and the PERONEAL NERVE.
Slippage of the FEMUR off the TIBIA.
The distal extremity of the leg in vertebrates, consisting of the tarsus (ANKLE); METATARSUS; phalanges; and the soft tissues surrounding these bones.
Mechanical compression of nerves or nerve roots from internal or external causes. These may result in a conduction block to nerve impulses (due to MYELIN SHEATH dysfunction) or axonal loss. The nerve and nerve sheath injuries may be caused by ISCHEMIA; INFLAMMATION; or a direct mechanical effect.
The propagation of the NERVE IMPULSE along the nerve away from the site of an excitation stimulus.
Slender processes of NEURONS, including the AXONS and their glial envelopes (MYELIN SHEATH). Nerve fibers conduct nerve impulses to and from the CENTRAL NERVOUS SYSTEM.
Renewal or physiological repair of damaged nerve tissue.
The thoracolumbar division of the autonomic nervous system. Sympathetic preganglionic fibers originate in neurons of the intermediolateral column of the spinal cord and project to the paravertebral and prevertebral ganglia, which in turn project to target organs. The sympathetic nervous system mediates the body's response to stressful situations, i.e., the fight or flight reactions. It often acts reciprocally to the parasympathetic system.
A general term most often used to describe severe or complete loss of muscle strength due to motor system disease from the level of the cerebral cortex to the muscle fiber. This term may also occasionally refer to a loss of sensory function. (From Adams et al., Principles of Neurology, 6th ed, p45)
Diseases of the peripheral nerves external to the brain and spinal cord, which includes diseases of the nerve roots, ganglia, plexi, autonomic nerves, sensory nerves, and motor nerves.
The 2nd cranial nerve which conveys visual information from the RETINA to the brain. The nerve carries the axons of the RETINAL GANGLION CELLS which sort at the OPTIC CHIASM and continue via the OPTIC TRACTS to the brain. The largest projection is to the lateral geniculate nuclei; other targets include the SUPERIOR COLLICULI and the SUPRACHIASMATIC NUCLEI. Though known as the second cranial nerve, it is considered part of the CENTRAL NERVOUS SYSTEM.
Interruption of NEURAL CONDUCTION in peripheral nerves or nerve trunks by the injection of a local anesthetic agent (e.g., LIDOCAINE; PHENOL; BOTULINUM TOXINS) to manage or treat pain.
Surgically placed electric conductors through which ELECTRIC STIMULATION of nerve tissue is delivered.
A tumor made up of nerve cells and nerve fibers. (Dorland, 27th ed)
A major nerve of the upper extremity. In humans, the fibers of the median nerve originate in the lower cervical and upper thoracic spinal cord (usually C6 to T1), travel via the brachial plexus, and supply sensory and motor innervation to parts of the forearm and hand.
Recording of the changes in electric potential of muscle by means of surface or needle electrodes.
A nerve originating in the lumbar spinal cord (usually L2 to L4) and traveling through the lumbar plexus to provide motor innervation to extensors of the thigh and sensory innervation to parts of the thigh, lower leg, and foot, and to the hip and knee joints.
Surgical reinnervation of a denervated peripheral target using a healthy donor nerve and/or its proximal stump. The direct connection is usually made to a healthy postlesional distal portion of a non-functioning nerve or implanted directly into denervated muscle or insensitive skin. Nerve sprouts will grow from the transferred nerve into the denervated elements and establish contact between them and the neurons that formerly controlled another area.
Gait abnormalities that are a manifestation of nervous system dysfunction. These conditions may be caused by a wide variety of disorders which affect motor control, sensory feedback, and muscle strength including: CENTRAL NERVOUS SYSTEM DISEASES; PERIPHERAL NERVOUS SYSTEM DISEASES; NEUROMUSCULAR DISEASES; or MUSCULAR DISEASES.
Injuries to the PERIPHERAL NERVES.
Diagnosis of disease states by recording the spontaneous electrical activity of tissues or organs or by the response to stimulation of electrically excitable tissue.
A monosynaptic reflex elicited by stimulating a nerve, particularly the tibial nerve, with an electric shock.
The bone of the lower leg lateral to and smaller than the tibia. In proportion to its length, it is the most slender of the long bones.
Use of electric potential or currents to elicit biological responses.
The joint that is formed by the inferior articular and malleolar articular surfaces of the TIBIA; the malleolar articular surface of the FIBULA; and the medial malleolar, lateral malleolar, and superior surfaces of the TALUS.
Walking aids generally having two handgrips and four legs.
The inferior part of the lower extremity between the KNEE and the ANKLE.
Surgical procedure by which a tendon is incised at its insertion and placed at an anatomical site distant from the original insertion. The tendon remains attached at the point of origin and takes over the function of a muscle inactivated by trauma or disease.
Contractile tissue that produces movement in animals.
Neurons which activate MUSCLE CELLS.
A subtype of striated muscle, attached by TENDONS to the SKELETON. Skeletal muscles are innervated and their movement can be consciously controlled. They are also called voluntary muscles.
Branch-like terminations of NERVE FIBERS, sensory or motor NEURONS. Endings of sensory neurons are the beginnings of afferent pathway to the CENTRAL NERVOUS SYSTEM. Endings of motor neurons are the terminals of axons at the muscle cells. Nerve endings which release neurotransmitters are called PRESYNAPTIC TERMINALS.
The 7th cranial nerve. The facial nerve has two parts, the larger motor root which may be called the facial nerve proper, and the smaller intermediate or sensory root. Together they provide efferent innervation to the muscles of facial expression and to the lacrimal and SALIVARY GLANDS, and convey afferent information for TASTE from the anterior two-thirds of the TONGUE and for TOUCH from the EXTERNAL EAR.
Treatment of muscles and nerves under pressure as a result of crush injuries.
The use of specifically placed small electrodes to deliver electrical impulses across the SKIN to relieve PAIN. It is used less frequently to produce ANESTHESIA.
The region of the lower limb between the FOOT and the LEG.
A major nerve of the upper extremity. In humans, the fibers of the ulnar nerve originate in the lower cervical and upper thoracic spinal cord (usually C7 to T1), travel via the medial cord of the brachial plexus, and supply sensory and motor innervation to parts of the hand and forearm.
Neurons which conduct NERVE IMPULSES to the CENTRAL NERVOUS SYSTEM.
Signal and data processing method that uses decomposition of wavelets to approximate, estimate, or compress signals with finite time and frequency domains. It represents a signal or data in terms of a fast decaying wavelet series from the original prototype wavelet, called the mother wavelet. This mathematical algorithm has been adopted widely in biomedical disciplines for data and signal processing in noise removal and audio/image compression (e.g., EEG and MRI).
An involuntary movement or exercise of function in a part, excited in response to a stimulus applied to the periphery and transmitted to the brain or spinal cord.
The 31 paired peripheral nerves formed by the union of the dorsal and ventral spinal roots from each spinal cord segment. The spinal nerve plexuses and the spinal roots are also included.
Nerve fibers that are capable of rapidly conducting impulses away from the neuron cell body.
The separation and isolation of tissues for surgical purposes, or for the analysis or study of their structures.
Peripheral, autonomic, and cranial nerve disorders that are associated with DIABETES MELLITUS. These conditions usually result from diabetic microvascular injury involving small blood vessels that supply nerves (VASA NERVORUM). Relatively common conditions which may be associated with diabetic neuropathy include third nerve palsy (see OCULOMOTOR NERVE DISEASES); MONONEUROPATHY; mononeuropathy multiplex; diabetic amyotrophy; a painful POLYNEUROPATHY; autonomic neuropathy; and thoracoabdominal neuropathy. (From Adams et al., Principles of Neurology, 6th ed, p1325)
NERVE GROWTH FACTOR is the first of a series of neurotrophic factors that were found to influence the growth and differentiation of sympathetic and sensory neurons. It is comprised of alpha, beta, and gamma subunits. The beta subunit is responsible for its growth stimulating activity.
The 5th and largest cranial nerve. The trigeminal nerve is a mixed motor and sensory nerve. The larger sensory part forms the ophthalmic, mandibular, and maxillary nerves which carry afferents sensitive to external or internal stimuli from the skin, muscles, and joints of the face and mouth and from the teeth. Most of these fibers originate from cells of the TRIGEMINAL GANGLION and project to the TRIGEMINAL NUCLEUS of the brain stem. The smaller motor part arises from the brain stem trigeminal motor nucleus and innervates the muscles of mastication.
Factors which enhance the growth potentialities of sensory and sympathetic nerve cells.
The outer covering of the body that protects it from the environment. It is composed of the DERMIS and the EPIDERMIS.
The motor nerve of the diaphragm. The phrenic nerve fibers originate in the cervical spinal column (mostly C4) and travel through the cervical plexus to the diaphragm.
Skeletal muscle structures that function as the MECHANORECEPTORS responsible for the stretch or myotactic reflex (REFLEX, STRETCH). They are composed of a bundle of encapsulated SKELETAL MUSCLE FIBERS, i.e., the intrafusal fibers (nuclear bag 1 fibers, nuclear bag 2 fibers, and nuclear chain fibers) innervated by SENSORY NEURONS.
A major nerve of the upper extremity. In humans the fibers of the radial nerve originate in the lower cervical and upper thoracic spinal cord (usually C5 to T1), travel via the posterior cord of the brachial plexus, and supply motor innervation to extensor muscles of the arm and cutaneous sensory fibers to extensor regions of the arm and hand.
A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
Twelve pairs of nerves that carry general afferent, visceral afferent, special afferent, somatic efferent, and autonomic efferent fibers.
Paired bundles of NERVE FIBERS entering and leaving the SPINAL CORD at each segment. The dorsal and ventral nerve roots join to form the mixed segmental spinal nerves. The dorsal roots are generally afferent, formed by the central projections of the spinal (dorsal root) ganglia sensory cells, and the ventral roots are efferent, comprising the axons of spinal motor and PREGANGLIONIC AUTONOMIC FIBERS.
A strong ligament of the knee that originates from the anterolateral surface of the medial condyle of the femur, passes posteriorly and inferiorly between the condyles, and attaches to the posterior intercondylar area of the tibia.
The resection or removal of the innervation of a muscle or muscle tissue.
Abrupt changes in the membrane potential that sweep along the CELL MEMBRANE of excitable cells in response to excitation stimuli.
Apparatus used to support, align, prevent, or correct deformities or to improve the function of movable parts of the body.
A sensory branch of the trigeminal (5th cranial) nerve. The ophthalmic nerve carries general afferents from the superficial division of the face including the eyeball, conjunctiva, upper eyelid, upper nose, nasal mucosa, and scalp.
Moving a patient into a specific position or POSTURE to facilitate examination, surgery, or for therapeutic purposes.
Nerve structures through which impulses are conducted from a peripheral part toward a nerve center.
Either of two extremities of four-footed non-primate land animals. It usually consists of a FEMUR; TIBIA; and FIBULA; tarsals; METATARSALS; and TOES. (From Storer et al., General Zoology, 6th ed, p73)
Neurons which send impulses peripherally to activate muscles or secretory cells.
Differentiated tissue of the central nervous system composed of NERVE CELLS, fibers, DENDRITES, and specialized supporting cells.
A partial or complete return to the normal or proper physiologic activity of an organ or part following disease or trauma.
A branch of the trigeminal (5th cranial) nerve. The mandibular nerve carries motor fibers to the muscles of mastication and sensory fibers to the teeth and gingivae, the face in the region of the mandible, and parts of the dura.
Cells specialized to transduce mechanical stimuli and relay that information centrally in the nervous system. Mechanoreceptor cells include the INNER EAR hair cells, which mediate hearing and balance, and the various somatosensory receptors, often with non-neural accessory structures.
A general term referring to a mild to moderate degree of muscular weakness, occasionally used as a synonym for PARALYSIS (severe or complete loss of motor function). In the older literature, paresis often referred specifically to paretic neurosyphilis (see NEUROSYPHILIS). "General paresis" and "general paralysis" may still carry that connotation. Bilateral lower extremity paresis is referred to as PARAPARESIS.
The domestic cat, Felis catus, of the carnivore family FELIDAE, comprising over 30 different breeds. The domestic cat is descended primarily from the wild cat of Africa and extreme southwestern Asia. Though probably present in towns in Palestine as long ago as 7000 years, actual domestication occurred in Egypt about 4000 years ago. (From Walker's Mammals of the World, 6th ed, p801)
The process of exocrine secretion of the SWEAT GLANDS, including the aqueous sweat from the ECCRINE GLANDS and the complex viscous fluids of the APOCRINE GLANDS.
Act of eliciting a response from a person or organism through physical contact.
PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS.

Specific and innervation-regulated expression of the intermediate filament protein nestin at neuromuscular and myotendinous junctions in skeletal muscle. (1/476)

The intermediate filament proteins nestin, vimentin, and desmin show a specific temporal expression pattern during the development of myofibers from myogenic precursor cells. Nestin and vimentin are actively expressed during early developmental stages to be later down-regulated, vimentin completely and nestin to minimal levels, whereas desmin expression begins later and is maintained in mature myofibers, in which desmin participates in maintaining structural integrity. In this study we have analyzed the expression levels and distribution pattern of nestin in intact and denervated muscle in rat and in human. Nestin immunoreactivity was specifically and focally localized in the sarcoplasm underneath neuromuscular junctions (NMJs) and in the vicinity of the myotendinous junctions (MTJs), ie, in regions associated with acetylcholine receptors (AChRs). This association prompted us to analyze nestin in neurogenically and myogenically denervated muscle. Immunoblot analysis disclosed a marked overall increase of accumulated nestin protein. Similar to the extrajunctional redistribution of AChRs in denervated myofibers, nestin immunoreactivity extended widely beyond the NMJ region. Re-innervation caused complete reversion of these changes. Our study demonstrates that the expression levels and distribution pattern of nestin are regulated by innervation, ie, signal transduction into myofibers.  (+info)

Uninjured C-fiber nociceptors develop spontaneous activity and alpha-adrenergic sensitivity following L6 spinal nerve ligation in monkey. (2/476)

We investigated whether uninjured cutaneous C-fiber nociceptors in primates develop abnormal responses after partial denervation of the skin. Partial denervation was induced by tightly ligating spinal nerve L6 that innervates the dorsum of the foot. Using an in vitro skin-nerve preparation, we recorded from uninjured single afferent nerve fibers in the superficial peroneal nerve. Recordings were made from 32 C-fiber nociceptors 2-3 wk after ligation and from 29 C-fiber nociceptors in control animals. Phenylephrine, a selective alpha1-adrenergic agonist, and UK14304 (UK), a selective alpha2-adrenergic agonist, were applied to the receptive field for 5 min in increasing concentrations from 0.1 to 100 microM. Nociceptors from in vitro control experiments were not significantly different from nociceptors recorded by us previously in in vivo experiments. In comparison to in vitro control animals, the afferents found in lesioned animals had 1) a significantly higher incidence of spontaneous activity, 2) a significantly higher incidence of response to phenylephrine, and 3) a higher incidence of response to UK. In lesioned animals, the peak response to phenylephrine was significantly greater than to UK, and the mechanical threshold of phenylephrine-sensitive afferents was significantly lower than for phenylephrine-insensitive afferents. Staining with protein gene product 9.5 revealed an approximately 55% reduction in the number of unmyelinated terminals in the epidermis of the lesioned limb compared with the contralateral limb. Thus uninjured cutaneous C-fiber nociceptors that innervate skin partially denervated by ligation of a spinal nerve acquire two abnormal properties: spontaneous activity and alpha-adrenergic sensitivity. These abnormalities in nociceptor function may contribute to neuropathic pain.  (+info)

Arousal from sleep shortens sympathetic burst latency in humans. (3/476)

1. Bursts of sympathetic activity in muscle nerves are phase-locked to the cardiac cycle by the sinoaortic baroreflexes. Acoustic arousal from non-rapid eye movement (NREM) sleep reduces the normally invariant interval between the R-wave of the electrocardiogram (ECG) and the peak of the corresponding sympathetic burst; however, the effects of other forms of sleep disruption (i.e. spontaneous arousals and apnoea-induced arousals) on this temporal relationship are unknown. 2. We simultaneously recorded muscle sympathetic nerve activity in the peroneal nerve (intraneural electrodes) and the ECG (surface electrodes) in seven healthy humans and three patients with sleep apnoea syndrome during NREM sleep. 3. In seven subjects, burst latencies were shortened subsequent to spontaneous K complexes (1.297 +/- 0.024 s, mean +/- s. e.m.) and spontaneous arousals (1.268 +/- 0.044 s) compared with latencies during periods of stable NREM sleep (1.369 +/- 0.023 s). In six subjects who demonstrated spontaneous apnoeas during sleep, apnoea per se did not alter burst latency relative to sleep with stable electroencephalogram (EEG) and breathing (1.313 +/- 0.038 vs. 1.342 +/- 0.026 s); however, following apnoea-induced EEG perturbations, burst latencies were reduced (1.214 +/- 0.034 s). 4. Arousal-induced reduction in sympathetic burst latency may reflect a temporary diminution of baroreflex buffering of sympathetic outflow. If so, the magnitude of arterial pressure perturbations during sleep (e.g. those caused by sleep disordered breathing and periodic leg movements) may be augmented by arousal.  (+info)

Activity-dependent slowing of conduction differentiates functional subtypes of C fibres innervating human skin. (4/476)

1. The effects of impulse activity on conduction in cutaneous C fibres have been examined in 46 microneurographic recordings from 11 normal subjects and 11 diabetic patients with normal nerve conduction. A tungsten microelectrode was inserted into a cutaneous nerve, usually the superficial peroneal close to the ankle, and intraneural microstimulation was used to identify an area of skin innervated. Three minute trains of 0.25 ms stimuli at 1, 2 and 4 Hz were then delivered to the surface of the skin, separated by intervals of 6 min with stimulation at 0.25 Hz. Slowing and block of conduction were measured from the nerve responses for up to seven C units per stimulation sequence. 2. Three types of C unit were distinguished by their responses to repetitive stimulation: type 1 units slowed progressively during the 3 min trains; slowing of type 2 units reached a plateau within 1 min; while type 3 units hardly slowed at all. Data from normal and diabetic subjects did not differ and were pooled. After 3 min at 2 Hz, the percentage increases in latency were for type 1, 28.3 +/- 9.7 (n = 63 units, mean +/- s.d.); for type 2, 5.2 +/- 1.6 (n = 14); and for type 3, 0.8 +/- 0.5 (n = 5), with no overlap. After 3 min at 4 Hz, 58 % of type 1 units (but no type 2 or 3 units) blocked intermittently. Recovery of latency after stimulation was faster for type 2 than for type 1 units, but conduction velocities of the three types were similar. 3. Type 1 units were identified as nociceptors and 7 type 2 units were identified as 'cold' fibres, activated by non-noxious cold, with no overlap in modality. None of the units tested was activated by weak mechanical stimuli or reflex sympathetic activation. 4. Spike waveforms were averaged for 18 type 1, 10 type 2 and 6 type 3 units. All units had predominantly triphasic action potentials with a major negative peak, but those of type 3 units were on average both smaller and briefer than those of type 1 and type 2 units. 5. It is concluded that repetitive electrical stimulation reliably differentiates nociceptive from cold-specific C fibres innervating human hairy skin, as has previously been shown for the rat. Cold fibres can propagate impulses continuously at much higher rates than nociceptive fibres. The nature of the type 3 units is unclear.  (+info)

Respiratory and cardiac modulation of single sympathetic vasoconstrictor and sudomotor neurones to human skin. (5/476)

1. The firing of single sympathetic neurones was recorded via tungsten microelectrodes in cutaneous fascicles of the peroneal nerve in awake humans. Studies were made of 17 vasoconstrictor neurones during cold-induced cutaneous vasoconstriction and eight sudomotor neurones during heat-induced sweating. Oligounitary recordings were obtained from 8 cutaneous vasconstrictor and 10 sudomotor sites. Skin blood flow was measured by laser Doppler flowmetry, and sweating by changes in skin electrical resistance within the innervation territory on the dorsum of the foot. 2. Perispike time histograms revealed respiratory modulation in 11 (65 %) vasoconstrictor and 4 (50 %) sudomotor neurones. After correcting for estimated conduction delays, the firing probability was higher in inspiration for both classes of neurone. Measured from the oligounitary recordings, the respiratory modulation indices were 67. 7 +/- 3.9 % for vasoconstrictor and 73.5 +/- 5.7 % for sudomotor neurones (means +/- s.e.m.). As previously found for sudomotor neurones, cardiac rhythmicity was expressed by 7 (41 %) vasoconstrictor neurones, 5 of which showed no significant coupling to respiration. Measured from the oligounitary records, the cardiac modulation of cutaneous vasoconstrictor activity was 58.6 +/- 4.9 %, compared with 74.4 +/- 6.4 % for sudomotor activity. 3. Both vasoconstrictor and sudomotor neurones displayed low average firing rates (0.53 and 0.62 Hz, respectively). The percentage of cardiac intervals in which units fired was 38 % and 35 %, respectively. Moreover, when considering only those cardiac intervals when a unit fired, vasoconstrictor and sudomotor neurones generated a single spike 66 % and 67 % of the time. Rarely were more than four spikes generated by a single neurone. 4. We conclude that human cutaneous vasoconstrictor and sudomotor neurones share several properties: both classes contain subpopulations that are modulated by respiration and/or the cardiac cycle. The data suggest that the intensity of a multi-unit burst of vasoconstrictor or sudomotor impulses is probably governed primarily by firing incidence and the recruitment of additional neurones, rather than by an increase in the number of spikes each unit contributes to a burst.  (+info)

Responses of sympathetic outflow to skin during caloric stimulation in humans. (6/476)

We previously showed that caloric vestibular stimulation elicits increases in sympathetic outflow to muscle (MSNA) in humans. The present study was conducted to determine the effect of this stimulation on sympathetic outflow to skin (SSNA). The SSNA in the tibial and peroneal nerves and nystagmus was recorded in nine subjects when the external meatus was irrigated with 50 ml of cold (10 degrees C) or warm (44 degrees C) water. During nystagmus, the SSNA in tibial and peroneal nerves decreased to 50 +/- 4% (with baseline value set as 100%) and 61 +/- 4%, respectively. The degree of SSNA suppression in both nerves was proportional to the maximum slow-phase velocity of nystagmus. After nystagmus, the SSNA increased to 166 +/- 7 and 168 +/- 6%, respectively, and the degree of motion sickness symptoms was correlated with this SSNA increase. These results suggest that the SSNA response differs from the MSNA response during caloric vestibular stimulation and that the SSNA response elicited in the initial period of caloric vestibular stimulation is different from that observed during the period of motion sickness symptoms.  (+info)

Induction of neurally mediated syncope with adenosine. (7/476)

BACKGROUND: Tilt testing is used to establish the diagnosis of neurally mediated syncope. However, applicability of the tilt test is limited by test sensitivity and length of time required to perform the test. We hypothesized that adenosine could facilitate the induction of neurally mediated syncope through its sympathomimetic effects and therefore could be used as an alternative to routine tilt testing. METHODS AND RESULTS: In protocol 1, the yield of adenosine tilt testing (12 mg while upright, followed by 60 degrees tilt for 5 minutes) and a 15-minute isoproterenol tilt test were compared in 84 patients with a negative 30-minute drug-free tilt test. In protocol 2, 100 patients underwent an initial adenosine tilt test followed by our routine tilt test (30-minute drug-free tilt followed by a 15-minute isoproterenol tilt). Six additional control patients underwent microneurography of the peroneal nerve to compare the sympathomimetic effects during bolus administration of adenosine and continuous infusion of isoproterenol. In protocol 1, the yields of adenosine (8 of 84, 10%) and isoproterenol (7 of 84, 8%) tilt testing were comparable (P=NS). In protocol 2, the yields of adenosine (19 of 100, 19%) and routine (22 of 100, 22%) tilt testing were also comparable (P=NS). Although the yield of adenosine tilt testing was comparable in both protocols, patients with a negative adenosine tilt test but a positive routine tilt test usually required isoproterenol to elicit the positive response. Microneurography confirmed discordant sympathetic activation after adenosine and isoproterenol administration. CONCLUSIONS: Adenosine is effective for the induction of neurally mediated syncope, with a diagnostic yield comparable to routine tilt testing. However, the discordant results obtained with adenosine and the isoproterenol phase of routine tilt testing suggest that adenosine and isoproterenol tilt testing may have complementary roles in eliciting a positive response. Therefore, a tilt protocol that uses an initial adenosine tilt followed, if necessary, by an isoproterenol tilt would be expected to increase the overall yield and reduce the duration of tilt testing.  (+info)

Aberrant neurofilament phosphorylation in sensory neurons of rats with diabetic neuropathy. (8/476)

Aberrant neurofilament phosphorylation occurs in many neurodegenerative diseases, and in this study, two animal models of type 1 diabetes--the spontaneously diabetic BB rat and the streptozocin-induced diabetic rat--have been used to determine whether such a phenomenon is involved in the etiology of the symmetrical sensory polyneuropathy commonly associated with diabetes. There was a two- to threefold (P < 0.05) elevation of neurofilament phosphorylation in lumbar dorsal root ganglia (DRG) of diabetic rats that was localized to perikarya of medium to large neurons using immunocytochemistry. Additionally, diabetes enhanced neurofilament M phosphorylation by 2.5-fold (P < 0.001) in sural nerve of BB rats. Neurofilaments are substrates of the mitogen-activated protein kinase (MAPK) family, which includes c-jun NH2-terminal kinase (JNK) or stress-activated protein kinase (SAPK1) and extracellular signal-regulated kinases (ERKs) 1 and 2. Diabetes induced a significant three- to fourfold (P < 0.05) increase in phosphorylation of a 54-kDa isoform of JNK in DRG and sural nerve, and this correlated with elevated c-Jun and neurofilament phosphorylation. In diabetes, ERK phosphorylation was also increased in the DRG, but not in sural nerve. Immunocytochemistry showed that JNK was present in sensory neuron perikarya and axons. Motoneuron perikarya and peroneal nerve of diabetic rats showed no evidence of increased neurofilament phosphorylation and failed to exhibit phosphorylation of JNK. It is hypothesized that in sensory neurons of diabetic rats, aberrant phosphorylation of neurofilament may contribute to the distal sensory axonopathy observed in diabetes.  (+info)

The Peroneal nerve, also known as the common fibular nerve, is a branch of the sciatic nerve that supplies the muscles of the lower leg and provides sensation to the skin on the outer part of the lower leg and the top of the foot. It winds around the neck of the fibula (calf bone) and can be vulnerable to injury in this area, leading to symptoms such as weakness or numbness in the foot and leg.

Peroneal neuropathies refer to conditions that cause damage or dysfunction to the peroneal nerve, which is a branch of the sciatic nerve. The peroneal nerve runs down the back of the leg and wraps around the fibula bone (the smaller of the two bones in the lower leg) before dividing into two branches that innervate the muscles and skin on the front and side of the lower leg and foot.

Peroneal neuropathies can cause various symptoms, including weakness or paralysis of the ankle and toe muscles, numbness or tingling in the top of the foot and along the outside of the lower leg, and difficulty lifting the foot (known as "foot drop"). These conditions can result from trauma, compression, diabetes, or other underlying medical conditions. Treatment for peroneal neuropathies may include physical therapy, bracing, medications to manage pain, and in some cases, surgery.

The Tibial nerve is a major branch of the sciatic nerve that originates in the lower back and runs through the buttock and leg. It provides motor (nerve impulses that control muscle movement) and sensory (nerve impulses that convey information about touch, temperature, and pain) innervation to several muscles and skin regions in the lower limb.

More specifically, the Tibial nerve supplies the following structures:

1. Motor Innervation: The Tibial nerve provides motor innervation to the muscles in the back of the leg (posterior compartment), including the calf muscles (gastrocnemius and soleus) and the small muscles in the foot (intrinsic muscles). These muscles are responsible for plantarflexion (pointing the foot downward) and inversion (turning the foot inward) of the foot.
2. Sensory Innervation: The Tibial nerve provides sensory innervation to the skin on the sole of the foot, as well as the heel and some parts of the lower leg.

The Tibial nerve travels down the leg, passing behind the knee and through the calf, where it eventually joins with the common fibular (peroneal) nerve to form the tibial-fibular trunk. This trunk then divides into several smaller nerves that innervate the foot's intrinsic muscles and skin.

Damage or injury to the Tibial nerve can result in various symptoms, such as weakness or paralysis of the calf and foot muscles, numbness or tingling sensations in the sole of the foot, and difficulty walking or standing on tiptoes.

The sural nerve is a purely sensory peripheral nerve in the lower leg and foot. It provides sensation to the outer ( lateral) aspect of the little toe and the adjacent side of the fourth toe, as well as a small portion of the skin on the back of the leg between the ankle and knee joints.

The sural nerve is formed by the union of branches from the tibial and common fibular nerves (branches of the sciatic nerve) in the lower leg. It runs down the calf, behind the lateral malleolus (the bony prominence on the outside of the ankle), and into the foot.

The sural nerve is often used as a donor nerve during nerve grafting procedures due to its consistent anatomy and relatively low risk for morbidity at the donor site.

Peripheral nerves are nerve fibers that transmit signals between the central nervous system (CNS, consisting of the brain and spinal cord) and the rest of the body. These nerves convey motor, sensory, and autonomic information, enabling us to move, feel, and respond to changes in our environment. They form a complex network that extends from the CNS to muscles, glands, skin, and internal organs, allowing for coordinated responses and functions throughout the body. Damage or injury to peripheral nerves can result in various neurological symptoms, such as numbness, weakness, or pain, depending on the type and severity of the damage.

The sciatic nerve is the largest and longest nerve in the human body, running from the lower back through the buttocks and down the legs to the feet. It is formed by the union of the ventral rami (branches) of the L4 to S3 spinal nerves. The sciatic nerve provides motor and sensory innervation to various muscles and skin areas in the lower limbs, including the hamstrings, calf muscles, and the sole of the foot. Sciatic nerve disorders or injuries can result in symptoms such as pain, numbness, tingling, or weakness in the lower back, hips, legs, and feet, known as sciatica.

Knee dislocation is a serious and uncommon orthopedic injury that occurs when the bones that form the knee joint (femur, tibia, and patella) are forced out of their normal position due to extreme trauma or force. This injury often requires immediate medical attention and reduction (repositioning) by a healthcare professional. If left untreated, it can lead to serious complications such as compartment syndrome, nerve damage, and long-term joint instability. It's important to note that knee dislocation is different from a kneecap (patellar) dislocation, which involves the patella sliding out of its groove in the femur.

In medical terms, the foot is the part of the lower limb that is distal to the leg and below the ankle, extending from the tarsus to the toes. It is primarily responsible for supporting body weight and facilitating movement through push-off during walking or running. The foot is a complex structure made up of 26 bones, 33 joints, and numerous muscles, tendons, ligaments, and nerves that work together to provide stability, balance, and flexibility. It can be divided into three main parts: the hindfoot, which contains the talus and calcaneus (heel) bones; the midfoot, which includes the navicular, cuboid, and cuneiform bones; and the forefoot, which consists of the metatarsals and phalanges that form the toes.

Nerve compression syndromes refer to a group of conditions characterized by the pressure or irritation of a peripheral nerve, causing various symptoms such as pain, numbness, tingling, and weakness in the affected area. This compression can occur due to several reasons, including injury, repetitive motion, bone spurs, tumors, or swelling. Common examples of nerve compression syndromes include carpal tunnel syndrome, cubital tunnel syndrome, radial nerve compression, and ulnar nerve entrapment at the wrist or elbow. Treatment options may include physical therapy, splinting, medications, injections, or surgery, depending on the severity and underlying cause of the condition.

Neural conduction is the process by which electrical signals, known as action potentials, are transmitted along the axon of a neuron (nerve cell) to transmit information between different parts of the nervous system. This electrical impulse is generated by the movement of ions across the neuronal membrane, and it propagates down the length of the axon until it reaches the synapse, where it can then stimulate the release of neurotransmitters to communicate with other neurons or target cells. The speed of neural conduction can vary depending on factors such as the diameter of the axon, the presence of myelin sheaths (which act as insulation and allow for faster conduction), and the temperature of the environment.

Nerve fibers are specialized structures that constitute the long, slender processes (axons) of neurons (nerve cells). They are responsible for conducting electrical impulses, known as action potentials, away from the cell body and transmitting them to other neurons or effector organs such as muscles and glands. Nerve fibers are often surrounded by supportive cells called glial cells and are grouped together to form nerve bundles or nerves. These fibers can be myelinated (covered with a fatty insulating sheath called myelin) or unmyelinated, which influences the speed of impulse transmission.

Nerve regeneration is the process of regrowth and restoration of functional nerve connections following damage or injury to the nervous system. This complex process involves various cellular and molecular events, such as the activation of support cells called glia, the sprouting of surviving nerve fibers (axons), and the reformation of neural circuits. The goal of nerve regeneration is to enable the restoration of normal sensory, motor, and autonomic functions impaired due to nerve damage or injury.

The sympathetic nervous system (SNS) is a part of the autonomic nervous system that operates largely below the level of consciousness, and it functions to produce appropriate physiological responses to perceived danger. It's often associated with the "fight or flight" response. The SNS uses nerve impulses to stimulate target organs, causing them to speed up (e.g., increased heart rate), prepare for action, or otherwise respond to stressful situations.

The sympathetic nervous system is activated due to stressful emotional or physical situations and it prepares the body for immediate actions. It dilates the pupils, increases heart rate and blood pressure, accelerates breathing, and slows down digestion. The primary neurotransmitter involved in this system is norepinephrine (also known as noradrenaline).

Paralysis is a loss of muscle function in part or all of your body. It can be localized, affecting only one specific area, or generalized, impacting multiple areas or even the entire body. Paralysis often occurs when something goes wrong with the way messages pass between your brain and muscles. In most cases, paralysis is caused by damage to the nervous system, especially the spinal cord. Other causes include stroke, trauma, infections, and various neurological disorders.

It's important to note that paralysis doesn't always mean a total loss of movement or feeling. Sometimes, it may just cause weakness or numbness in the affected area. The severity and extent of paralysis depend on the underlying cause and the location of the damage in the nervous system.

Peripheral Nervous System (PNS) diseases, also known as Peripheral Neuropathies, refer to conditions that affect the functioning of the peripheral nervous system, which includes all the nerves outside the brain and spinal cord. These nerves transmit signals between the central nervous system (CNS) and the rest of the body, controlling sensations, movements, and automatic functions such as heart rate and digestion.

PNS diseases can be caused by various factors, including genetics, infections, toxins, metabolic disorders, trauma, or autoimmune conditions. The symptoms of PNS diseases depend on the type and extent of nerve damage but often include:

1. Numbness, tingling, or pain in the hands and feet
2. Muscle weakness or cramps
3. Loss of reflexes
4. Decreased sensation to touch, temperature, or vibration
5. Coordination problems and difficulty with balance
6. Sexual dysfunction
7. Digestive issues, such as constipation or diarrhea
8. Dizziness or fainting due to changes in blood pressure

Examples of PNS diseases include Guillain-Barre syndrome, Charcot-Marie-Tooth disease, diabetic neuropathy, and peripheral nerve injuries. Treatment for these conditions varies depending on the underlying cause but may involve medications, physical therapy, lifestyle changes, or surgery.

The optic nerve, also known as the second cranial nerve, is the nerve that transmits visual information from the retina to the brain. It is composed of approximately one million nerve fibers that carry signals related to vision, such as light intensity and color, from the eye's photoreceptor cells (rods and cones) to the visual cortex in the brain. The optic nerve is responsible for carrying this visual information so that it can be processed and interpreted by the brain, allowing us to see and perceive our surroundings. Damage to the optic nerve can result in vision loss or impairment.

A nerve block is a medical procedure in which an anesthetic or neurolytic agent is injected near a specific nerve or bundle of nerves to block the transmission of pain signals from that area to the brain. This technique can be used for both diagnostic and therapeutic purposes, such as identifying the source of pain, providing temporary or prolonged relief, or facilitating surgical procedures in the affected region.

The injection typically contains a local anesthetic like lidocaine or bupivacaine, which numbs the nerve, preventing it from transmitting pain signals. In some cases, steroids may also be added to reduce inflammation and provide longer-lasting relief. Depending on the type of nerve block and its intended use, the injection might be administered close to the spine (neuraxial blocks), at peripheral nerves (peripheral nerve blocks), or around the sympathetic nervous system (sympathetic nerve blocks).

While nerve blocks are generally safe, they can have side effects such as infection, bleeding, nerve damage, or in rare cases, systemic toxicity from the anesthetic agent. It is essential to consult with a qualified medical professional before undergoing this procedure to ensure proper evaluation, technique, and post-procedure care.

An implantable neurostimulator is a type of medical device that is surgically placed inside the body to deliver electrical stimulation to specific nerves or areas of the brain. This can be used to treat a variety of neurological conditions, such as chronic pain, epilepsy, Parkinson's disease, and essential tremor.

The device typically consists of one or more electrodes that are implanted near the target nerve or brain region, connected to a pulse generator that is implanted under the skin, usually in the chest or abdomen. The patient or healthcare provider can program the pulse generator to deliver electrical stimulation at specific times and intensities, which can help to modulate the activity of the targeted nerves and alleviate symptoms.

Implantable neurostimulators are typically considered when other treatments have failed or are not well-tolerated. While they are generally safe and effective, there are some risks associated with surgery and long-term use, such as infection, device malfunction, and discomfort at the implantation site. Therefore, careful consideration and discussion with a healthcare provider is necessary before deciding to proceed with this type of treatment.

A neuroma is not a specific type of tumor, but rather refers to a benign (non-cancerous) growth or swelling of nerve tissue. The most common type of neuroma is called a Morton's neuroma, which typically occurs between the third and fourth toes in the foot. It develops as a result of chronic irritation, compression, or trauma to the nerves leading to the toes, causing them to thicken and enlarge.

Morton's neuroma can cause symptoms such as pain, numbness, tingling, or burning sensations in the affected area. Treatment options for Morton's neuroma may include rest, ice, orthotics, physical therapy, medication, or in some cases, surgery. It is essential to consult a healthcare professional if you suspect you have a neuroma or are experiencing related symptoms.

The median nerve is one of the major nerves in the human body, providing sensation and motor function to parts of the arm and hand. It originates from the brachial plexus, a network of nerves that arise from the spinal cord in the neck. The median nerve travels down the arm, passing through the cubital tunnel at the elbow, and continues into the forearm and hand.

In the hand, the median nerve supplies sensation to the palm side of the thumb, index finger, middle finger, and half of the ring finger. It also provides motor function to some of the muscles that control finger movements, allowing for flexion of the fingers and opposition of the thumb.

Damage to the median nerve can result in a condition called carpal tunnel syndrome, which is characterized by numbness, tingling, and weakness in the hand and fingers.

Electromyography (EMG) is a medical diagnostic procedure that measures the electrical activity of skeletal muscles during contraction and at rest. It involves inserting a thin needle electrode into the muscle to record the electrical signals generated by the muscle fibers. These signals are then displayed on an oscilloscope and may be heard through a speaker.

EMG can help diagnose various neuromuscular disorders, such as muscle weakness, numbness, or pain, and can distinguish between muscle and nerve disorders. It is often used in conjunction with other diagnostic tests, such as nerve conduction studies, to provide a comprehensive evaluation of the nervous system.

EMG is typically performed by a neurologist or a physiatrist, and the procedure may cause some discomfort or pain, although this is usually minimal. The results of an EMG can help guide treatment decisions and monitor the progression of neuromuscular conditions over time.

The femoral nerve is a major nerve in the thigh region of the human body. It originates from the lumbar plexus, specifically from the ventral rami (anterior divisions) of the second, third, and fourth lumbar nerves (L2-L4). The femoral nerve provides motor and sensory innervation to various muscles and areas in the lower limb.

Motor Innervation:
The femoral nerve is responsible for providing motor innervation to several muscles in the anterior compartment of the thigh, including:

1. Iliacus muscle
2. Psoas major muscle
3. Quadriceps femoris muscle (consisting of four heads: rectus femoris, vastus lateralis, vastus medialis, and vastus intermedius)

These muscles are involved in hip flexion, knee extension, and stabilization of the hip joint.

Sensory Innervation:
The sensory distribution of the femoral nerve includes:

1. Anterior and medial aspects of the thigh
2. Skin over the anterior aspect of the knee and lower leg (via the saphenous nerve, a branch of the femoral nerve)

The saphenous nerve provides sensation to the skin on the inner side of the leg and foot, as well as the medial malleolus (the bony bump on the inside of the ankle).

In summary, the femoral nerve is a crucial component of the lumbar plexus that controls motor functions in the anterior thigh muscles and provides sensory innervation to the anterior and medial aspects of the thigh and lower leg.

A nerve transfer is a surgical procedure where a functioning nerve is connected to an injured nerve to restore movement, sensation or function. The functioning nerve, called the donor nerve, usually comes from another less critical location in the body and has spare nerve fibers that can be used to reinnervate the injured nerve, called the recipient nerve.

During the procedure, a small section of the donor nerve is carefully dissected and prepared for transfer. The recipient nerve is also prepared by removing any damaged or non-functioning portions. The two ends are then connected using microsurgical techniques under a microscope. Over time, the nerve fibers from the donor nerve grow along the recipient nerve and reinnervate the muscles or sensory structures that were previously innervated by the injured nerve.

Nerve transfers can be used to treat various types of nerve injuries, including brachial plexus injuries, facial nerve palsy, and peripheral nerve injuries. The goal of the procedure is to restore function as quickly and efficiently as possible, allowing for a faster recovery and improved quality of life for the patient.

A gait disorder is a disturbance in the ability to walk that can't be attributed to physical disabilities such as weakness or paralysis. Neurologic gait disorders are those specifically caused by underlying neurological conditions. These disorders can result from damage to the brain, spinal cord, or peripheral nerves that disrupts communication between the muscles and the brain.

Neurologic gait disorders can present in various ways, including:

1. **Spastic Gait:** This is a stiff, foot-dragging walk caused by increased muscle tone (hypertonia) and stiffness (spasticity). It's often seen in conditions like cerebral palsy or multiple sclerosis.

2. **Ataxic Gait:** This is a broad-based, unsteady, and irregular walk caused by damage to the cerebellum, which affects balance and coordination. Conditions such as cerebellar atrophy or stroke can cause this type of gait disorder.

3. **Parkinsonian Gait:** This is a shuffling walk with small steps, flexed knees, and difficulty turning. It's often seen in Parkinson's disease.

4. **Neuropathic Gait:** This is a high-stepping walk caused by foot drop (difficulty lifting the front part of the foot), which results from damage to the peripheral nerves. Conditions such as diabetic neuropathy or Guillain-Barre syndrome can cause this type of gait disorder.

5. **Choreic Gait:** This is an irregular, dance-like walk caused by involuntary movements (chorea) seen in conditions like Huntington's disease.

6. **Mixed Gait:** Sometimes, a person may exhibit elements of more than one type of gait disorder.

The specific type of gait disorder can provide important clues about the underlying neurological condition and help guide diagnosis and treatment.

Peripheral nerve injuries refer to damage or trauma to the peripheral nerves, which are the nerves outside the brain and spinal cord. These nerves transmit information between the central nervous system (CNS) and the rest of the body, including sensory, motor, and autonomic functions. Peripheral nerve injuries can result in various symptoms, depending on the type and severity of the injury, such as numbness, tingling, weakness, or paralysis in the affected area.

Peripheral nerve injuries are classified into three main categories based on the degree of damage:

1. Neuropraxia: This is the mildest form of nerve injury, where the nerve remains intact but its function is disrupted due to a local conduction block. The nerve fiber is damaged, but the supporting structures remain intact. Recovery usually occurs within 6-12 weeks without any residual deficits.
2. Axonotmesis: In this type of injury, there is damage to both the axons and the supporting structures (endoneurium, perineurium). The nerve fibers are disrupted, but the connective tissue sheaths remain intact. Recovery can take several months or even up to a year, and it may be incomplete, with some residual deficits possible.
3. Neurotmesis: This is the most severe form of nerve injury, where there is complete disruption of the nerve fibers and supporting structures (endoneurium, perineurium, epineurium). Recovery is unlikely without surgical intervention, which may involve nerve grafting or repair.

Peripheral nerve injuries can be caused by various factors, including trauma, compression, stretching, lacerations, or chemical exposure. Treatment options depend on the type and severity of the injury and may include conservative management, such as physical therapy and pain management, or surgical intervention for more severe cases.

Electrodiagnosis, also known as electromyography (EMG), is a medical diagnostic procedure that evaluates the health and function of muscles and nerves. It measures the electrical activity of skeletal muscles at rest and during contraction, as well as the conduction of electrical signals along nerves.

The test involves inserting a thin needle electrode into the muscle to record its electrical activity. The physician will ask the patient to contract and relax the muscle while the electrical activity is recorded. The resulting data can help diagnose various neuromuscular disorders, such as nerve damage or muscle diseases, by identifying abnormalities in the electrical signals.

Electrodiagnosis can be used to diagnose conditions such as carpal tunnel syndrome, peripheral neuropathy, muscular dystrophy, and amyotrophic lateral sclerosis (ALS), among others. It is a valuable tool in the diagnosis and management of neuromuscular disorders, helping physicians to develop appropriate treatment plans for their patients.

The H-reflex, or Hoffmann reflex, is a monosynaptic reflex that tests the integrity of the Ia afferent nerve fibers and the corresponding alpha motor neurons in the spinal cord. It's often used in clinical and research settings to assess the function of the lower motor neuron and the sensitivity of the stretch reflex.

The H-reflex is elicited by applying an electrical stimulus to a sensory nerve, typically the tibial nerve at the popliteal fossa or the median nerve at the wrist. This stimulation activates Ia afferent fibers, which then synapse directly onto alpha motor neurons in the spinal cord, causing a muscle contraction in the corresponding agonist muscle (e.g., soleus or flexor carpi radialis). The latency of the H-reflex provides information about the conduction velocity of Ia afferent fibers and the excitability of alpha motor neurons.

It's important to note that the H-reflex is influenced by various factors, such as muscle length, contraction state, and the overall excitability of the nervous system. Therefore, interpreting H-reflex results requires a thorough understanding of these influencing factors and careful consideration of the clinical context.

The fibula is a slender bone located in the lower leg of humans and other vertebrates. It runs parallel to the larger and more robust tibia, and together they are known as the bones of the leg or the anterior tibial segment. The fibula is the lateral bone in the leg, positioned on the outside of the tibia.

In humans, the fibula extends from the knee joint proximally to the ankle joint distally. Its proximal end, called the head of the fibula, articulates with the lateral condyle of the tibia and forms part of the inferior aspect of the knee joint. The narrowed portion below the head is known as the neck of the fibula.

The shaft of the fibula, also called the body of the fibula, is a long, thin structure that descends from the neck and serves primarily for muscle attachment rather than weight-bearing functions. The distal end of the fibula widens to form the lateral malleolus, which is an important bony landmark in the ankle region. The lateral malleolus articulates with the talus bone of the foot and forms part of the ankle joint.

The primary functions of the fibula include providing attachment sites for muscles that act on the lower leg, ankle, and foot, as well as contributing to the stability of the ankle joint through its articulation with the talus bone. Fractures of the fibula can occur due to various injuries, such as twisting or rotational forces applied to the ankle or direct trauma to the lateral aspect of the lower leg.

Electric stimulation, also known as electrical nerve stimulation or neuromuscular electrical stimulation, is a therapeutic treatment that uses low-voltage electrical currents to stimulate nerves and muscles. It is often used to help manage pain, promote healing, and improve muscle strength and mobility. The electrical impulses can be delivered through electrodes placed on the skin or directly implanted into the body.

In a medical context, electric stimulation may be used for various purposes such as:

1. Pain management: Electric stimulation can help to block pain signals from reaching the brain and promote the release of endorphins, which are natural painkillers produced by the body.
2. Muscle rehabilitation: Electric stimulation can help to strengthen muscles that have become weak due to injury, illness, or surgery. It can also help to prevent muscle atrophy and improve range of motion.
3. Wound healing: Electric stimulation can promote tissue growth and help to speed up the healing process in wounds, ulcers, and other types of injuries.
4. Urinary incontinence: Electric stimulation can be used to strengthen the muscles that control urination and reduce symptoms of urinary incontinence.
5. Migraine prevention: Electric stimulation can be used as a preventive treatment for migraines by applying electrical impulses to specific nerves in the head and neck.

It is important to note that electric stimulation should only be administered under the guidance of a qualified healthcare professional, as improper use can cause harm or discomfort.

The ankle joint, also known as the talocrural joint, is the articulation between the bones of the lower leg (tibia and fibula) and the talus bone in the foot. It is a synovial hinge joint that allows for dorsiflexion and plantarflexion movements, which are essential for walking, running, and jumping. The ankle joint is reinforced by strong ligaments on both sides to provide stability during these movements.

"Walker" is not a medical term per se, but it is often used in the medical field to refer to a mobility aid that helps individuals who have difficulty walking independently. Walkers are typically made of lightweight metal and have four legs that provide stability and support. Some walkers come with wheels or glides on the front legs to make it easier for users to move around. They may also include brakes, seats, and baskets for added functionality.

Walkers can be beneficial for people who have mobility limitations due to various medical conditions such as arthritis, stroke, fractures, neurological disorders, or aging-related issues. Using a walker can help reduce the risk of falls, improve balance, increase independence, and enhance overall quality of life.

It is essential to consult with a healthcare professional before using a walker to ensure proper fit, adjustment, and usage techniques for maximum safety and effectiveness.

In medical terms, the leg refers to the lower portion of the human body that extends from the knee down to the foot. It includes the thigh (femur), lower leg (tibia and fibula), foot, and ankle. The leg is primarily responsible for supporting the body's weight and enabling movements such as standing, walking, running, and jumping.

The leg contains several important structures, including bones, muscles, tendons, ligaments, blood vessels, nerves, and joints. These structures work together to provide stability, support, and mobility to the lower extremity. Common medical conditions that can affect the leg include fractures, sprains, strains, infections, peripheral artery disease, and neurological disorders.

A tendon transfer is a surgical procedure where a healthy tendon is moved to rebalance or reinforce a muscle that has become weak or paralyzed due to injury, disease, or nerve damage. The transferred tendon attaches to the bone in a new position, allowing it to power a different movement or stabilize a joint. This procedure helps restore function and improve mobility in the affected area.

A muscle is a soft tissue in our body that contracts to produce force and motion. It is composed mainly of specialized cells called muscle fibers, which are bound together by connective tissue. There are three types of muscles: skeletal (voluntary), smooth (involuntary), and cardiac. Skeletal muscles attach to bones and help in movement, while smooth muscles are found within the walls of organs and blood vessels, helping with functions like digestion and circulation. Cardiac muscle is the specific type that makes up the heart, allowing it to pump blood throughout the body.

Motor neurons are specialized nerve cells in the brain and spinal cord that play a crucial role in controlling voluntary muscle movements. They transmit electrical signals from the brain to the muscles, enabling us to perform actions such as walking, talking, and swallowing. There are two types of motor neurons: upper motor neurons, which originate in the brain's motor cortex and travel down to the brainstem and spinal cord; and lower motor neurons, which extend from the brainstem and spinal cord to the muscles. Damage or degeneration of these motor neurons can lead to various neurological disorders, such as amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy (SMA).

Skeletal muscle, also known as striated or voluntary muscle, is a type of muscle that is attached to bones by tendons or aponeuroses and functions to produce movements and support the posture of the body. It is composed of long, multinucleated fibers that are arranged in parallel bundles and are characterized by alternating light and dark bands, giving them a striped appearance under a microscope. Skeletal muscle is under voluntary control, meaning that it is consciously activated through signals from the nervous system. It is responsible for activities such as walking, running, jumping, and lifting objects.

Nerve endings, also known as terminal branches or sensory receptors, are the specialized structures present at the termination point of nerve fibers (axons) that transmit electrical signals to and from the central nervous system (CNS). They primarily function in detecting changes in the external environment or internal body conditions and converting them into electrical impulses.

There are several types of nerve endings, including:

1. Free Nerve Endings: These are unencapsulated nerve endings that respond to various stimuli like temperature, pain, and touch. They are widely distributed throughout the body, especially in the skin, mucous membranes, and visceral organs.

2. Encapsulated Nerve Endings: These are wrapped by specialized connective tissue sheaths, which can modify their sensitivity to specific stimuli. Examples include Pacinian corpuscles (responsible for detecting deep pressure and vibration), Meissner's corpuscles (for light touch), Ruffini endings (for stretch and pressure), and Merkel cells (for sustained touch).

3. Specialised Nerve Endings: These are nerve endings that respond to specific stimuli, such as auditory, visual, olfactory, gustatory, and vestibular information. They include hair cells in the inner ear, photoreceptors in the retina, taste buds in the tongue, and olfactory receptors in the nasal cavity.

Nerve endings play a crucial role in relaying sensory information to the CNS for processing and initiating appropriate responses, such as reflex actions or conscious perception of the environment.

The facial nerve, also known as the seventh cranial nerve (CN VII), is a mixed nerve that carries both sensory and motor fibers. Its functions include controlling the muscles involved in facial expressions, taste sensation from the anterior two-thirds of the tongue, and secretomotor function to the lacrimal and salivary glands.

The facial nerve originates from the brainstem and exits the skull through the internal acoustic meatus. It then passes through the facial canal in the temporal bone before branching out to innervate various structures of the face. The main branches of the facial nerve include:

1. Temporal branch: Innervates the frontalis, corrugator supercilii, and orbicularis oculi muscles responsible for eyebrow movements and eyelid closure.
2. Zygomatic branch: Supplies the muscles that elevate the upper lip and wrinkle the nose.
3. Buccal branch: Innervates the muscles of the cheek and lips, allowing for facial expressions such as smiling and puckering.
4. Mandibular branch: Controls the muscles responsible for lower lip movement and depressing the angle of the mouth.
5. Cervical branch: Innervates the platysma muscle in the neck, which helps to depress the lower jaw and wrinkle the skin of the neck.

Damage to the facial nerve can result in various symptoms, such as facial weakness or paralysis, loss of taste sensation, and dry eyes or mouth due to impaired secretion.

A nerve crush injury is a type of peripheral nerve injury that occurs when there is excessive pressure or compression applied to a nerve, causing it to become damaged or dysfunctional. This can happen due to various reasons such as trauma from accidents, surgical errors, or prolonged pressure on the nerve from tight casts, clothing, or positions.

The compression disrupts the normal functioning of the nerve, leading to symptoms such as numbness, tingling, weakness, or pain in the affected area. In severe cases, a nerve crush injury can cause permanent damage to the nerve, leading to long-term disability or loss of function. Treatment for nerve crush injuries typically involves relieving the pressure on the nerve, providing supportive care, and in some cases, surgical intervention may be necessary to repair the damaged nerve.

Transcutaneous Electrical Nerve Stimulation (TENS) is a non-invasive method of pain relief that involves the use of low-voltage electrical currents. A TENS device, which is usually small and portable, delivers these currents through electrodes that are placed on the skin near the site of pain. The electrical impulses stimulate nerve fibers, which can help to block the transmission of pain signals to the brain, thereby reducing the perception of pain.

TENS is thought to work through a number of different mechanisms, including the gate control theory of pain and the release of endorphins, which are natural painkillers produced by the body. It is generally considered safe, with few side effects, and can be used in conjunction with other forms of pain management.

TENS is often used to treat chronic pain conditions such as arthritis, fibromyalgia, and lower back pain, as well as acute pain from injuries or surgery. However, its effectiveness varies from person to person, and it may not work for everyone. It is important to consult with a healthcare provider before using TENS, particularly if you have any underlying medical conditions or are taking medication that could interact with the electrical currents.

The ankle, also known as the talocrural region, is the joint between the leg and the foot. It is a synovial hinge joint that allows for dorsiflexion and plantarflexion movements. The ankle is composed of three bones: the tibia and fibula of the lower leg, and the talus of the foot. The bottom portion of the tibia and fibula, called the malleoli, form a mortise that surrounds and articulates with the talus.

The ankle joint is strengthened by several ligaments, including the medial (deltoid) ligament and lateral ligament complex. The ankle also contains important nerves and blood vessels that provide sensation and circulation to the foot.

Damage to the ankle joint, such as sprains or fractures, can result in pain, swelling, and difficulty walking. Proper care and rehabilitation are essential for maintaining the health and function of the ankle joint.

The Ulnar nerve is one of the major nerves in the forearm and hand, which provides motor function to the majority of the intrinsic muscles of the hand (except for those innervated by the median nerve) and sensory innervation to the little finger and half of the ring finger. It originates from the brachial plexus, passes through the cubital tunnel at the elbow, and continues down the forearm, where it runs close to the ulna bone. The ulnar nerve then passes through the Guyon's canal in the wrist before branching out to innervate the hand muscles and provide sensation to the skin on the little finger and half of the ring finger.

Afferent neurons, also known as sensory neurons, are a type of nerve cell that conducts impulses or signals from peripheral receptors towards the central nervous system (CNS), which includes the brain and spinal cord. These neurons are responsible for transmitting sensory information such as touch, temperature, pain, sound, and light to the CNS for processing and interpretation. Afferent neurons have specialized receptor endings that detect changes in the environment and convert them into electrical signals, which are then transmitted to the CNS via synapses with other neurons. Once the signals reach the CNS, they are processed and integrated with other information to produce a response or reaction to the stimulus.

Wavelet analysis is not a medical term, but rather a mathematical technique that has been applied in various fields, including medicine. It is a method used to analyze data signals or functions by decomposing them into different frequency components and time-shifted versions of the original signal. This allows for the examination of how the frequency content of a signal changes over time.

In the medical field, wavelet analysis has been applied in various ways such as:

1. Image processing: Wavelet analysis can be used to enhance medical images like MRI and CT scans by reducing noise while preserving important details.
2. Signal processing: It can be used to analyze physiological signals like ECG, EEG, and blood pressure waves to detect anomalies or patterns that may indicate diseases or conditions.
3. Data compression: Wavelet analysis is employed in the compression of large medical datasets, such as those generated by functional magnetic resonance imaging (fMRI) and positron emission tomography (PET) scans.
4. Biomedical engineering: Wavelet analysis can be used to model and simulate complex biological systems, like the cardiovascular system or the nervous system.

In summary, wavelet analysis is a mathematical technique that has been applied in various medical fields for image processing, signal processing, data compression, and biomedical engineering purposes.

A reflex is an automatic, involuntary and rapid response to a stimulus that occurs without conscious intention. In the context of physiology and neurology, it's a basic mechanism that involves the transmission of nerve impulses between neurons, resulting in a muscle contraction or glandular secretion.

Reflexes are important for maintaining homeostasis, protecting the body from harm, and coordinating movements. They can be tested clinically to assess the integrity of the nervous system, such as the knee-j jerk reflex, which tests the function of the L3-L4 spinal nerve roots and the sensitivity of the stretch reflex arc.

Spinal nerves are the bundles of nerve fibers that transmit signals between the spinal cord and the rest of the body. There are 31 pairs of spinal nerves in the human body, which can be divided into five regions: 8 cervical, 12 thoracic, 5 lumbar, 5 sacral, and 1 coccygeal. Each spinal nerve carries both sensory information (such as touch, temperature, and pain) from the periphery to the spinal cord, and motor information (such as muscle control) from the spinal cord to the muscles and other structures in the body. Spinal nerves also contain autonomic fibers that regulate involuntary functions such as heart rate, digestion, and blood pressure.

An axon is a long, slender extension of a neuron (a type of nerve cell) that conducts electrical impulses (nerve impulses) away from the cell body to target cells, such as other neurons or muscle cells. Axons can vary in length from a few micrometers to over a meter long and are typically surrounded by a myelin sheath, which helps to insulate and protect the axon and allows for faster transmission of nerve impulses.

Axons play a critical role in the functioning of the nervous system, as they provide the means by which neurons communicate with one another and with other cells in the body. Damage to axons can result in serious neurological problems, such as those seen in spinal cord injuries or neurodegenerative diseases like multiple sclerosis.

In medical terms, dissection refers to the separation of the layers of a biological tissue or structure by cutting or splitting. It is often used to describe the process of surgically cutting through tissues, such as during an operation to separate organs or examine their internal structures.

However, "dissection" can also refer to a pathological condition in which there is a separation of the layers of a blood vessel wall by blood, creating a false lumen or aneurysm. This type of dissection is most commonly seen in the aorta and can be life-threatening if not promptly diagnosed and treated.

In summary, "dissection" has both surgical and pathological meanings related to the separation of tissue layers, and it's essential to consider the context in which the term is used.

Diabetic neuropathies refer to a group of nerve disorders that are caused by diabetes. High blood sugar levels can injure nerves throughout the body, but diabetic neuropathies most commonly affect the nerves in the legs and feet.

There are four main types of diabetic neuropathies:

1. Peripheral neuropathy: This is the most common type of diabetic neuropathy. It affects the nerves in the legs and feet, causing symptoms such as numbness, tingling, burning, or shooting pain.
2. Autonomic neuropathy: This type of neuropathy affects the autonomic nerves, which control involuntary functions such as heart rate, blood pressure, digestion, and bladder function. Symptoms may include dizziness, fainting, digestive problems, sexual dysfunction, and difficulty regulating body temperature.
3. Proximal neuropathy: Also known as diabetic amyotrophy, this type of neuropathy affects the nerves in the hips, thighs, or buttocks, causing weakness, pain, and difficulty walking.
4. Focal neuropathy: This type of neuropathy affects a single nerve or group of nerves, causing symptoms such as weakness, numbness, or pain in the affected area. Focal neuropathies can occur anywhere in the body, but they are most common in the head, torso, and legs.

The risk of developing diabetic neuropathies increases with the duration of diabetes and poor blood sugar control. Other factors that may contribute to the development of diabetic neuropathies include genetics, age, smoking, and alcohol consumption.

Nerve Growth Factor (NGF) is a small secreted protein that is involved in the growth, maintenance, and survival of certain neurons (nerve cells). It was the first neurotrophin to be discovered and is essential for the development and function of the nervous system. NGF binds to specific receptors on the surface of nerve cells and helps to promote their differentiation, axonal growth, and synaptic plasticity. Additionally, NGF has been implicated in various physiological processes such as inflammation, immune response, and wound healing. Deficiencies or excesses of NGF have been linked to several neurological disorders, including Alzheimer's disease, Parkinson's disease, and pain conditions.

The trigeminal nerve, also known as the fifth cranial nerve or CNV, is a paired nerve that carries both sensory and motor information. It has three major branches: ophthalmic (V1), maxillary (V2), and mandibular (V3). The ophthalmic branch provides sensation to the forehead, eyes, and upper portion of the nose; the maxillary branch supplies sensation to the lower eyelid, cheek, nasal cavity, and upper lip; and the mandibular branch is responsible for sensation in the lower lip, chin, and parts of the oral cavity, as well as motor function to the muscles involved in chewing. The trigeminal nerve plays a crucial role in sensations of touch, pain, temperature, and pressure in the face and mouth, and it also contributes to biting, chewing, and swallowing functions.

Nerve Growth Factors (NGFs) are a family of proteins that play an essential role in the growth, maintenance, and survival of certain neurons (nerve cells). They were first discovered by Rita Levi-Montalcini and Stanley Cohen in 1956. NGF is particularly crucial for the development and function of the peripheral nervous system, which connects the central nervous system to various organs and tissues throughout the body.

NGF supports the differentiation and survival of sympathetic and sensory neurons during embryonic development. In adults, NGF continues to regulate the maintenance and repair of these neurons, contributing to neuroplasticity – the brain's ability to adapt and change over time. Additionally, NGF has been implicated in pain transmission and modulation, as well as inflammatory responses.

Abnormal levels or dysfunctional NGF signaling have been associated with various medical conditions, including neurodegenerative diseases (e.g., Alzheimer's and Parkinson's), chronic pain disorders, and certain cancers (e.g., small cell lung cancer). Therefore, understanding the role of NGF in physiological and pathological processes may provide valuable insights into developing novel therapeutic strategies for these conditions.

In medical terms, the skin is the largest organ of the human body. It consists of two main layers: the epidermis (outer layer) and dermis (inner layer), as well as accessory structures like hair follicles, sweat glands, and oil glands. The skin plays a crucial role in protecting us from external factors such as bacteria, viruses, and environmental hazards, while also regulating body temperature and enabling the sense of touch.

The phrenic nerve is a motor nerve that originates from the cervical spine (C3-C5) and descends through the neck to reach the diaphragm, which is the primary muscle used for breathing. The main function of the phrenic nerve is to innervate the diaphragm and control its contraction and relaxation, thereby enabling respiration.

Damage or injury to the phrenic nerve can result in paralysis of the diaphragm, leading to difficulty breathing and potentially causing respiratory failure. Certain medical conditions, such as neuromuscular disorders, spinal cord injuries, and tumors, can affect the phrenic nerve and impair its function.

Muscle spindles are specialized sensory organs found within the muscle belly, which primarily function as proprioceptors, providing information about the length and rate of change in muscle length. They consist of small, encapsulated bundles of intrafusal muscle fibers that are interspersed among the extrafusal muscle fibers (the ones responsible for force generation).

Muscle spindles have two types of sensory receptors called primary and secondary endings. Primary endings are located near the equatorial region of the intrafusal fiber, while secondary endings are situated more distally. These endings detect changes in muscle length and transmit this information to the central nervous system (CNS) through afferent nerve fibers.

The activation of muscle spindles plays a crucial role in reflexive responses, such as the stretch reflex (myotatic reflex), which helps maintain muscle tone and joint stability. Additionally, they contribute to our sense of body position and movement awareness, known as kinesthesia.

The Radial nerve is a major peripheral nerve in the human body that originates from the brachial plexus, which is a network of nerves formed by the union of the ventral rami (anterior divisions) of spinal nerves C5-T1. The radial nerve provides motor function to extensor muscles of the upper limb and sensation to parts of the skin on the back of the arm, forearm, and hand.

More specifically, the radial nerve supplies motor innervation to:

* Extensor muscles of the shoulder (e.g., teres minor, infraspinatus)
* Rotator cuff muscles
* Elbow joint stabilizers (e.g., lateral head of the triceps)
* Extensors of the wrist, fingers, and thumb

The radial nerve also provides sensory innervation to:

* Posterior aspect of the upper arm (from the lower third of the humerus to the elbow)
* Lateral forearm (from the lateral epicondyle of the humerus to the wrist)
* Dorsum of the hand (skin over the radial side of the dorsum, including the first web space)

Damage or injury to the radial nerve may result in various symptoms, such as weakness or paralysis of the extensor muscles, numbness or tingling sensations in the affected areas, and difficulty with extension movements of the wrist, fingers, and thumb. Common causes of radial nerve injuries include fractures of the humerus bone, compression during sleep or prolonged pressure on the nerve (e.g., from crutches), and entrapment syndromes like radial tunnel syndrome.

Muscle contraction is the physiological process in which muscle fibers shorten and generate force, leading to movement or stability of a body part. This process involves the sliding filament theory where thick and thin filaments within the sarcomeres (the functional units of muscles) slide past each other, facilitated by the interaction between myosin heads and actin filaments. The energy required for this action is provided by the hydrolysis of adenosine triphosphate (ATP). Muscle contractions can be voluntary or involuntary, and they play a crucial role in various bodily functions such as locomotion, circulation, respiration, and posture maintenance.

Cranial nerves are a set of twelve pairs of nerves that originate from the brainstem and skull, rather than the spinal cord. These nerves are responsible for transmitting sensory information (such as sight, smell, hearing, and taste) to the brain, as well as controlling various muscles in the head and neck (including those involved in chewing, swallowing, and eye movement). Each cranial nerve has a specific function and is named accordingly. For example, the optic nerve (cranial nerve II) transmits visual information from the eyes to the brain, while the vagus nerve (cranial nerve X) controls parasympathetic functions in the body such as heart rate and digestion.

Spinal nerve roots are the initial parts of spinal nerves that emerge from the spinal cord through the intervertebral foramen, which are small openings between each vertebra in the spine. These nerve roots carry motor, sensory, and autonomic fibers to and from specific regions of the body. There are 31 pairs of spinal nerve roots in total, with 8 cervical, 12 thoracic, 5 lumbar, 5 sacral, and 1 coccygeal pair. Each root has a dorsal (posterior) and ventral (anterior) ramus that branch off to form the peripheral nervous system. Irritation or compression of these nerve roots can result in pain, numbness, weakness, or loss of reflexes in the affected area.

The Posterior Cruciate Ligament (PCL) is one of the major ligaments in the knee, providing stability to the joint. It is a strong band of tissue located in the back of the knee, connecting the thighbone (femur) to the shinbone (tibia). The PCL limits the backward motion of the tibia relative to the femur and provides resistance to forces that tend to push the tibia backwards. It also assists in maintaining the overall alignment and function of the knee joint during various movements and activities. Injuries to the PCL are less common compared to injuries to the Anterior Cruciate Ligament (ACL) but can still occur due to high-energy trauma, such as motor vehicle accidents or sports incidents involving direct impact to the front of the knee.

Muscle denervation is a medical term that refers to the loss of nerve supply to a muscle or group of muscles. This can occur due to various reasons, such as injury to the nerves, nerve compression, or certain medical conditions like neuromuscular disorders. When the nerve supply to the muscle is interrupted, it can lead to muscle weakness, atrophy (wasting), and ultimately, paralysis.

In denervation, the communication between the nervous system and the muscle is disrupted, which means that the muscle no longer receives signals from the brain to contract and move. Over time, this can result in significant muscle wasting and disability, depending on the severity and extent of the denervation.

Denervation may be treated with various therapies, including physical therapy, medication, or surgical intervention, such as nerve grafting or muscle transfers, to restore function and prevent further muscle wasting. The specific treatment approach will depend on the underlying cause and severity of the denervation.

An action potential is a brief electrical signal that travels along the membrane of a nerve cell (neuron) or muscle cell. It is initiated by a rapid, localized change in the permeability of the cell membrane to specific ions, such as sodium and potassium, resulting in a rapid influx of sodium ions and a subsequent efflux of potassium ions. This ion movement causes a brief reversal of the electrical potential across the membrane, which is known as depolarization. The action potential then propagates along the cell membrane as a wave, allowing the electrical signal to be transmitted over long distances within the body. Action potentials play a crucial role in the communication and functioning of the nervous system and muscle tissue.

Orthotic devices are custom-made or prefabricated appliances designed to align, support, prevent deformity, or improve the function of movable body parts. They are frequently used in the treatment of various musculoskeletal disorders, such as foot and ankle conditions, knee problems, spinal alignment issues, and hand or wrist ailments. These devices can be adjustable or non-adjustable and are typically made from materials like plastic, metal, leather, or fabric. They work by redistributing forces across joints, correcting alignment, preventing unwanted movements, or accommodating existing deformities. Examples of orthotic devices include ankle-foot orthoses, knee braces, back braces, wrist splints, and custom-made foot insoles.

The ophthalmic nerve, also known as the first cranial nerve or CN I, is a sensory nerve that primarily transmits information about vision, including light intensity and color, and sensation in the eye and surrounding areas. It is responsible for the sensory innervation of the upper eyelid, conjunctiva, cornea, iris, ciliary body, and nasal cavity. The ophthalmic nerve has three major branches: the lacrimal nerve, frontal nerve, and nasociliary nerve. Damage to this nerve can result in various visual disturbances and loss of sensation in the affected areas.

Patient positioning in a medical context refers to the arrangement and placement of a patient's body in a specific posture or alignment on a hospital bed, examination table, or other medical device during medical procedures, surgeries, or diagnostic imaging examinations. The purpose of patient positioning is to optimize the patient's comfort, ensure their safety, facilitate access to the surgical site or area being examined, enhance the effectiveness of medical interventions, and improve the quality of medical images in diagnostic tests.

Proper patient positioning can help prevent complications such as pressure ulcers, nerve injuries, and respiratory difficulties. It may involve adjusting the height and angle of the bed, using pillows, blankets, or straps to support various parts of the body, and communicating with the patient to ensure they are comfortable and aware of what to expect during the procedure.

In surgical settings, patient positioning is carefully planned and executed by a team of healthcare professionals, including surgeons, anesthesiologists, nurses, and surgical technicians, to optimize surgical outcomes and minimize risks. In diagnostic imaging examinations, such as X-rays, CT scans, or MRIs, patient positioning is critical for obtaining high-quality images that can aid in accurate diagnosis and treatment planning.

Afferent pathways, also known as sensory pathways, refer to the neural connections that transmit sensory information from the peripheral nervous system to the central nervous system (CNS), specifically to the brain and spinal cord. These pathways are responsible for carrying various types of sensory information, such as touch, temperature, pain, pressure, vibration, hearing, vision, and taste, to the CNS for processing and interpretation.

The afferent pathways begin with sensory receptors located throughout the body, which detect changes in the environment and convert them into electrical signals. These signals are then transmitted via afferent neurons, also known as sensory neurons, to the spinal cord or brainstem. Within the CNS, the information is further processed and integrated with other neural inputs before being relayed to higher cognitive centers for conscious awareness and response.

Understanding the anatomy and physiology of afferent pathways is essential for diagnosing and treating various neurological conditions that affect sensory function, such as neuropathies, spinal cord injuries, and brain disorders.

A hindlimb, also known as a posterior limb, is one of the pair of extremities that are located distally to the trunk in tetrapods (four-legged vertebrates) and include mammals, birds, reptiles, and amphibians. In humans and other primates, hindlimbs are equivalent to the lower limbs, which consist of the thigh, leg, foot, and toes.

The primary function of hindlimbs is locomotion, allowing animals to move from one place to another. However, they also play a role in other activities such as balance, support, and communication. In humans, the hindlimbs are responsible for weight-bearing, standing, walking, running, and jumping.

In medical terminology, the term "hindlimb" is not commonly used to describe human anatomy. Instead, healthcare professionals use terms like lower limbs or lower extremities to refer to the same region of the body. However, in comparative anatomy and veterinary medicine, the term hindlimb is still widely used to describe the corresponding structures in non-human animals.

Efferent neurons are specialized nerve cells that transmit signals from the central nervous system (CNS), which includes the brain and spinal cord, to effector organs such as muscles or glands. These signals typically result in a response or action, hence the term "efferent," derived from the Latin word "efferre" meaning "to carry away."

Efferent neurons are part of the motor pathway and can be further classified into two types:

1. Somatic efferent neurons: These neurons transmit signals to skeletal muscles, enabling voluntary movements and posture maintenance. They have their cell bodies located in the ventral horn of the spinal cord and send their axons through the ventral roots to innervate specific muscle fibers.
2. Autonomic efferent neurons: These neurons are responsible for controlling involuntary functions, such as heart rate, digestion, respiration, and pupil dilation. They have a two-neuron chain arrangement, with the preganglionic neuron having its cell body in the CNS (brainstem or spinal cord) and synapsing with the postganglionic neuron in an autonomic ganglion near the effector organ. Autonomic efferent neurons can be further divided into sympathetic, parasympathetic, and enteric subdivisions based on their functions and innervation patterns.

In summary, efferent neurons are a critical component of the nervous system, responsible for transmitting signals from the CNS to various effector organs, ultimately controlling and coordinating numerous bodily functions and responses.

Nerve tissue, also known as neural tissue, is a type of specialized tissue that is responsible for the transmission of electrical signals and the processing of information in the body. It is a key component of the nervous system, which includes the brain, spinal cord, and peripheral nerves. Nerve tissue is composed of two main types of cells: neurons and glial cells.

Neurons are the primary functional units of nerve tissue. They are specialized cells that are capable of generating and transmitting electrical signals, known as action potentials. Neurons have a unique structure, with a cell body (also called the soma) that contains the nucleus and other organelles, and processes (dendrites and axons) that extend from the cell body and are used to receive and transmit signals.

Glial cells, also known as neuroglia or glia, are non-neuronal cells that provide support and protection for neurons. There are several different types of glial cells, including astrocytes, oligodendrocytes, microglia, and Schwann cells. These cells play a variety of roles in the nervous system, such as providing structural support, maintaining the proper environment for neurons, and helping to repair and regenerate nerve tissue after injury.

Nerve tissue is found throughout the body, but it is most highly concentrated in the brain and spinal cord, which make up the central nervous system (CNS). The peripheral nerves, which are the nerves that extend from the CNS to the rest of the body, also contain nerve tissue. Nerve tissue is responsible for transmitting sensory information from the body to the brain, controlling muscle movements, and regulating various bodily functions such as heart rate, digestion, and respiration.

"Recovery of function" is a term used in medical rehabilitation to describe the process in which an individual regains the ability to perform activities or tasks that were previously difficult or impossible due to injury, illness, or disability. This can involve both physical and cognitive functions. The goal of recovery of function is to help the person return to their prior level of independence and participation in daily activities, work, and social roles as much as possible.

Recovery of function may be achieved through various interventions such as physical therapy, occupational therapy, speech-language therapy, and other rehabilitation strategies. The specific approach used will depend on the individual's needs and the nature of their impairment. Recovery of function can occur spontaneously as the body heals, or it may require targeted interventions to help facilitate the process.

It is important to note that recovery of function does not always mean a full return to pre-injury or pre-illness levels of ability. Instead, it often refers to the person's ability to adapt and compensate for any remaining impairments, allowing them to achieve their maximum level of functional independence and quality of life.

The mandibular nerve is a branch of the trigeminal nerve (the fifth cranial nerve), which is responsible for sensations in the face and motor functions such as biting and chewing. The mandibular nerve provides both sensory and motor innervation to the lower third of the face, below the eye and nose down to the chin.

More specifically, it carries sensory information from the lower teeth, lower lip, and parts of the oral cavity, as well as the skin over the jaw and chin. It also provides motor innervation to the muscles of mastication (chewing), which include the masseter, temporalis, medial pterygoid, and lateral pterygoid muscles.

Damage to the mandibular nerve can result in numbness or loss of sensation in the lower face and mouth, as well as weakness or difficulty with chewing and biting.

Mechanoreceptors are specialized sensory receptor cells that convert mechanical stimuli such as pressure, tension, or deformation into electrical signals that can be processed and interpreted by the nervous system. They are found in various tissues throughout the body, including the skin, muscles, tendons, joints, and internal organs. Mechanoreceptors can detect different types of mechanical stimuli depending on their specific structure and location. For example, Pacinian corpuscles in the skin respond to vibrations, while Ruffini endings in the joints detect changes in joint angle and pressure. Overall, mechanoreceptors play a crucial role in our ability to perceive and interact with our environment through touch, proprioception (the sense of the position and movement of body parts), and visceral sensation (awareness of internal organ activity).

Paresis is a medical term that refers to a partial loss of voluntary muscle function. It is often described as muscle weakness, and it can affect one or several parts of the body. Paresis can be caused by various conditions, including nerve damage, stroke, spinal cord injuries, multiple sclerosis, and infections like polio or botulism. The severity of paresis can range from mild to severe, depending on the underlying cause and the specific muscles involved. Treatment for paresis typically focuses on addressing the underlying condition causing it.

"Cat" is a common name that refers to various species of small carnivorous mammals that belong to the family Felidae. The domestic cat, also known as Felis catus or Felis silvestris catus, is a popular pet and companion animal. It is a subspecies of the wildcat, which is found in Europe, Africa, and Asia.

Domestic cats are often kept as pets because of their companionship, playful behavior, and ability to hunt vermin. They are also valued for their ability to provide emotional support and therapy to people. Cats are obligate carnivores, which means that they require a diet that consists mainly of meat to meet their nutritional needs.

Cats are known for their agility, sharp senses, and predatory instincts. They have retractable claws, which they use for hunting and self-defense. Cats also have a keen sense of smell, hearing, and vision, which allow them to detect prey and navigate their environment.

In medical terms, cats can be hosts to various parasites and diseases that can affect humans and other animals. Some common feline diseases include rabies, feline leukemia virus (FeLV), feline immunodeficiency virus (FIV), and toxoplasmosis. It is important for cat owners to keep their pets healthy and up-to-date on vaccinations and preventative treatments to protect both the cats and their human companions.

Sweating, also known as perspiration, is the production of sweat by the sweat glands in the skin in response to heat, physical exertion, hormonal changes, or emotional stress. Sweat is a fluid composed mainly of water, with small amounts of sodium chloride, lactate, and urea. It helps regulate body temperature by releasing heat through evaporation on the surface of the skin. Excessive sweating, known as hyperhidrosis, can be a medical condition that may require treatment.

Physical stimulation, in a medical context, refers to the application of external forces or agents to the body or its tissues to elicit a response. This can include various forms of touch, pressure, temperature, vibration, or electrical currents. The purpose of physical stimulation may be therapeutic, as in the case of massage or physical therapy, or diagnostic, as in the use of reflex tests. It is also used in research settings to study physiological responses and mechanisms.

In a broader sense, physical stimulation can also refer to the body's exposure to physical activity or exercise, which can have numerous health benefits, including improving cardiovascular function, increasing muscle strength and flexibility, and reducing the risk of chronic diseases.

Blood pressure is the force exerted by circulating blood on the walls of the blood vessels. It is measured in millimeters of mercury (mmHg) and is given as two figures:

1. Systolic pressure: This is the pressure when the heart pushes blood out into the arteries.
2. Diastolic pressure: This is the pressure when the heart rests between beats, allowing it to fill with blood.

Normal blood pressure for adults is typically around 120/80 mmHg, although this can vary slightly depending on age, sex, and other factors. High blood pressure (hypertension) is generally considered to be a reading of 130/80 mmHg or higher, while low blood pressure (hypotension) is usually defined as a reading below 90/60 mmHg. It's important to note that blood pressure can fluctuate throughout the day and may be affected by factors such as stress, physical activity, and medication use.

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The sural communicating nerve (colloquially the peroneal communicating nerve) is one of the components of the sural nerve ... Huelke found of the 159 samples that the peroneal communicating nerve arose from the common peroneal nerve with the lateral ... "The origin of the peroneal communicating nerve" that describes the origins and pathways of the peroneal communicating nerve. He ... prevalence of nerves with a sural communicating nerve. Ramakrishnan et al found that type 1 nerves (only sural nerve complex ...
The peroneal nerve runs near to it. Starkey, Chad (2009). Examination of Orthopedic and Athletic Injuries (3rd ed.). ... Rubel, I. F.; Schwarzbard, I; Leonard, A; Cece, D (2004). "Anatomic location of the peroneal nerve at the level of the proximal ...
There is evidence that sustained squatting may cause bilateral peroneal nerve palsy.[citation needed] A common name for this ... Toğrol, E. (2000). "Bilateral peroneal nerve palsy induced by prolonged squatting". Military Medicine. 165 (3): 240-2. doi: ...
... increased the risk for surgical treatment of radial nerve entrapment. Posture induced common peroneal nerve (CPN) palsy is ... While nerve decompression may be used on any nerve, nerve resection should only be used on purely sensory nerves when the loss ... The superior cluneal nerves, middle cluneal nerves, posterior femoral cutaneous nerve, lateral femoral cutaneous nerve are all ... Outcomes for nerve resection is similar to nerve decompression. One disadvantage of nerve resections is that traumatic injury ...
"Entrapment of crural branches of the common peroneal nerve". Advanced Peripheral Nerve Surgery and Minimal Invasive Spinal ...
... sural nerve and lesser saphenous vein (which might be ligated), and branches of the superficial peroneal nerve; Proceeding ... Another complication is superficial peroneal nerve distribution sensation reduction. Generalized ligaments laxity may also ... peroneal tendon exploration would require a posterolateral longitudinal incision; Surgeons care for peroneal tendons, ...
Common peroneal nerve dysfunction Archived 2016-07-06 at the Wayback Machine, MedlinePlus Medical Encyclopedia Golden, Tim (May ... This incapacitates the leg by hitting the common peroneal nerve. According to The New York Times: By Dec. 3, Mr. Habibullah's ... Several U.S. soldiers hit the chained man with so-called "peroneal strikes," or severe blows to the side of the leg above the ... He had taken at least 9 peroneal strikes from two MPs for being "noncompliant and combative."] ... When Sgt. James P. Boland ...
Pigott TJ, Jefferson D (1991). "Idiopathic common peroneal nerve palsy--a review of thirteen cases". British Journal of ... This alters actin's interaction with the ADF/cofilin system, which regulates the dynamics of nerve cell cytoskeleton formation ... in Schwann cells causes a specific pattern of expression for the genes involved in the myelinization of this type of nerve cell ...
... a common name for bilateral peroneal nerve palsy that may be triggered by sustained squatting Third nerve palsy, involving ... "Toğrol E. Bilateral peroneal nerve palsy induced by prolonged squatting. Mil Med. 2000 Mar;165(3):240-2". Findarticles.com. ... impairment of cranial nerves Cerebral palsy, a neural disorder caused by intracranial lesions Conjugate gaze palsy, a disorder ... cranial nerve III Dan Agin, More Than Genes: What Science Can Tell Us About Toxic Chemicals, Development, and the Risk to Our ...
The fibularis brevis is supplied by the superficial fibular (peroneal) nerve. The fibularis brevis is the strongest abductor of ... Nerves and Nerve Injuries, San Diego: Academic Press, pp. 627-645, doi:10.1016/b978-0-12-410390-0.00049-4, ISBN 978-0-12-410390 ... The tendon itself can develop tendinopathy or the common peroneal sheath develop tenosynovitis. Terminologia Anatomica ... Peroneal Tendons, and Long Flexors of the Toes", Baxter's the Foot and Ankle in Sport (Second Edition), Philadelphia: Mosby, pp ...
At the moment just before the heel off phase of gait occurs, the stimulator delivers a stimulus to the common peroneal nerve, ... The stimulated nerve bundle includes motor nerves (efferent nerves-descending nerves from the central nervous system to muscles ... and sensory nerves (afferent nerves-ascending nerves from sensory organs to the central nervous system). The electrical charge ... The first commercially available FES devices treated foot drop by stimulating the peroneal nerve during gait. In this case, a ...
Damage to the common peroneal nerve or tibial nerve may also occur. Nerve problems, if they occur, often persist to a variable ... If the nerves and artery are intact the ligaments may be repaired after a few days. Multiple surgeries may be required. In just ... Medina O, Arom GA, Yeranosian MG, Petrigliano FA, McAllister DR (September 2014). "Vascular and nerve injury after knee ...
The dorsalis pedis artery is at risk when injecting anaesthetic into the deep peroneal nerve. Ultrasound can be used to help to ... It is also at risk during anaesthesia of the deep peroneal nerve. The dorsalis pedis artery is located 1/3 from medial ... Shastri, Uma; Kwofie, Kwesi; Salviz, Emine Aysu; Xu, Daquan; Hadzic, Admir (2014). "54 - Lower Extremity Nerve Blocks". ...
"New Tendon Transfer for Correction of Drop-foot in Common Peroneal Nerve Palsy". Clinical Orthopaedics and Related Research. ... It may also be useful to detect abnormal nerve pattern such as median-to-ulnar nerve anastomosis, which may influence the ... Tendon transfers provide a substitute which can be permanent or temporary, when muscle function is lost either due to nerve ... Omer, George E. (2004-08-01). "Tendon transfers for traumatic nerve injuries". Journal of the American Society for Surgery of ...
... under it are found also the anterior tibial vessels and deep peroneal nerve. It is found on the lateral side of the lower leg, ... Peroneal retinacula This article incorporates text in the public domain from page 488 of the 20th edition of Gray's Anatomy ( ...
the development of peroneal nerve palsy following damage to the common peroneal nerve. extra-osseous ("outside of the bone") ... as dissection near the proximal end may risk severing the common peroneal nerve. Instead, reducing the proximal fibula at the ...
This can target the peroneal nerve rendering the attacked leg numb and paralyzed. Muay Thai practitioners are taught to ...
Examples of nerves whose cutaneous branches have been examined are the: 1. Superficial fibular nerve or peroneal nerve ( ... Sural nerve (SN) stimulation results in a reflex that is both phase and intensity dependent. The sural nerve innervates the ... Sural nerve (innervating the lateral portion of the foot)4. Superficial branch of radial nerve (innervating forearm and hand on ... Tibial nerve (TN) stimulation demonstrates a phase dependent response, in which the muscle activation varies depending on what ...
The tourniquet should not be placed on the ulnar nerve or the peroneal nerve. The silicone ring device cannot be used on ... This may stem the flow of blood, but side effects such as soft tissue damage and nerve damage may occur. There are three types ... Unlike the historical mechanical tourniquets, the device reduces the risk of nerve paralysis. The surgical tourniquet version ... Richards RL (May 1951). "Ischaemic lesions of peripheral nerves: a review". Journal of Neurology, Neurosurgery, and Psychiatry ...
Toe extensors (extensor hallucis longus, extensor digitorum longus) are innervated by the deep peroneal nerve. Loss of normal ... Afferent: Nociception detected in the S1 dermatome and travels up the tibial nerve to the sciatic nerve to roots of L5,S1 and ... electrically stimulating peripheral nerves during a nerve conduction study Gonda sign - flexing and suddenly releasing the 4th ... Efferent: Motor response back through the L5,S1 roots to the sciatic nerve to its bifurcation. Toe flexors are innervated by ...
The authors state: "Our case was operated, as both the cutaneous and deep branches of the peroneal nerve were involved causing ... Plexiform neurofibromas can grow from nerves in the skin or from more internal nerve bundles, and can be very large (with mass ... "A case of isolated giant plexiform neurofibroma involving all branches of the common peroneal nerve". Archives of Orthopaedic ... A neurofibroma is a benign nerve-sheath tumor in the peripheral nervous system. In 90% of cases, they are found as stand-alone ...
It is accompanied by the anterior tibial vein, and the deep peroneal nerve, along its course. It crosses the anterior aspect of ...
The deep peroneal nerve passes under the retinaculum while the superficial peroneal nerve is outside of it. The inferior ... the tibial nerve, and the tendon of the flexor hallucis longus muscle. The fibular retinacula hold the tendons of the fibularis ...
Nerve supplied by lateral terminal branch of Deep Peroneal Nerve (deep fibular nerve) (proximal sciatic branches S1, S2). Same ...
They often mimic a variety of other diseases including ischemic stroke, peroneal nerve palsy and intracranial neurologic ... In standard MS, they are a result of inflammation of the optic nerve, known as optic neuritis. The effects of optic neuritis ... how MS results in physical fatigue but it is known that the repetitive usage of the same neural pathways results in nerve fiber ...
A peroneal strike is a temporarily disabling blow to the common fibular (peroneal) nerve of the leg, just above the knee. The ... The peroneal strike was used against detainees during the 2002 Bagram torture and prisoner abuse scandal. Charley horse Pain ... The strike is commonly made with the knee, a baton, or shin kick, but can be done by anything forcefully impacting the nerve. ...
The tibialis anterior overlaps the anterior tibial vessels and deep peroneal nerve in the upper part of the leg. The tibialis ... The tibialis anterior muscle is innervated by the deep fibular nerve, and recurrent genicular nerve (L4). A deep portion of the ...
At the popliteal fossa, the sciatic nerve divides into its two branches: The tibial and the common peroneal nerve. If surgery ... It is done above the knee on the posterior leg where the sciatic nerve starts splitting into the common peroneal and tibial ... A sciatic nerve block is a nerve block that uses local anesthetic to achieve analgesia in the leg. The block works by affecting ... The sciatic nerve is located in the gluteus maximus muscle, where the block is performed. The sciatic nerve can be blocked at ...
Between it and the tibialis anterior are the upper portions of the anterior tibial vessels and deep peroneal nerve. The muscle ... and the peroneal muscles on the lateral side. ...
Peroneal nerve paralysis usually leads to neuromuscular disorder, peroneal nerve injury, or foot drop which can be symptoms of ... Causing factors of peroneal nerve palsy are such as musculoskeletal or peroneal nerve injuries. Usually paralysis occurs at the ... Dysfunction of a single nerve such as the common peroneal nerve is called a mononeuropathy. Mononeuropathy means the nerve ... Most studies reported that about 30% of peroneal nerve palsy is followed from knee dislocations. Peroneal nerve injury occurs ...
This condition is also called common fibular nerve dysfunction. ... nerve dysfunction is due to damage to the peroneal nerve ... This condition is also called common fibular nerve dysfunction. ... nerve dysfunction is due to damage to the peroneal nerve ... Common fibular nerve dysfunction; Neuropathy - common peroneal nerve; Peroneal nerve injury; Peroneal nerve palsy; Fibular ... Common peroneal nerve dysfunction is due to damage to the peroneal nerve leading to loss of movement or sensation in the foot ...
The common peroneal nerve runs alongside the sciatic nerve, from the femur to the buttocks. It then courses further down on its ... The deep peroneal nerve makes up one section of the common peroneal nerve. ... The deep peroneal nerve makes up one section of the common peroneal nerve. The common peroneal nerve runs alongside the sciatic ... The nerve then splits inside the neck of the fibula into two parts: the deep peroneal nerve and the superficial peroneal nerve. ...
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The deep peroneal nerve block is easy to perform and may constitute part of an ankle block. ... Deep peroneal nerve block is one of the 2 deep nerve blocks at the level of the ankle. ... the nerve divides into the superficial and deep peroneal nerves. The deep peroneal nerve (or the anterior tibial nerve) begins ... The deep peroneal nerve is one of the 2 deep nerves at the ankle. The deep peroneal nerve may be blocked as a part of a total ...
electrical stimulation; peroneal nerve; stroke; long-term training effect; therapeutic effect; temporary carry-over effect; ... Training and orthotic effects related to functional electrical stimulation of the peroneal nerve in stroke. Journal of ... Training and orthotic effects related to functional electrical stimulation of the peroneal nerve in stroke. ...
The peroneal nerve splits off from the tibial nerve behind the knee. Peroneal nerve dsfunction is damage to the peroneal nerve ... contains Common Peroneal Nerve (L4, L5; S1, S2) Common Fibular (Peroneal) Nerve,The Ankle and Foot Nov 26, 2009 I had peroneal ... but when I try to look for them I find peroneal nerve glides or superficial peroneal nerve glides. The tibial nerve is done ... Peroneal nerve involvement by adding Inversion and Plantar flexion Jan 1, 2006 With the elongation of the nerve bed, the nerve ...
Effect of electrical stimulation of the cranial tibial muscle after end-to-side neurorrhaphy of the peroneal nerve in rats. ... The muscle and nerve morphometry showed superiority of group ES+ESN over ESN group in all parameters. CONCLUSION: Electrical ... PURPOSE: To investigate the efficiency of electrical stimulation in the muscle maintenance and nerve regeneration after end-to- ... The peroneal functional index showed that group ESN + ES equaled that of the Control group and showed an evolution of 60.5% ...
After pathological examination, the case was diagnosed as IPT of peroneal nerve, and the patient received no further therapy. ... Inflammatory pseudotumor of the peroneal nerve: case report and literature review.. Dina El Demellawy, James Bain, Hameed ... However, they are amenable to surgical cure with nerve-sparing surgery. Thus, despite their rarity, on dealing with neural S100 ... revealed a thickening in the posterolateral aspect of the popliteal fossa and features consistent with peroneal nerve palsy. ...
... femoral cutaneous nerve Saphenous nerve Obturator nerve Common peroneal nerve Superficial peroneal nerve Deep peroneal nerve ... Iliohypogastric nerve Ilioinguinal nerve Genitofemoral nerve Femoral nerve Lateral ... Nerve entrapment syndromes of the lower extremity can involve the following nerves and branches thereof: ... Deep peroneal nerve. The deep peroneal nerve, the other branch of the common peroneal nerve, originates just distal to the ...
The deep peroneal nerve block is easy to perform and may constitute part of an ankle block. ... Deep peroneal nerve block is one of the 2 deep nerve blocks at the level of the ankle. ... the nerve divides into the superficial and deep peroneal nerves. The deep peroneal nerve (or the anterior tibial nerve) begins ... The deep peroneal nerve is one of the 2 deep nerves at the ankle. The deep peroneal nerve may be blocked as a part of a total ...
Regional block of the superficial peroneal nerve allows for rapid anesthetization of the dorsum of the foot, which allows for ... The superficial peroneal nerve arises from the common peroneal nerve, which also gives rise to the deep peroneal nerve. The ... encoded search term (Superficial Peroneal Nerve Block) and Superficial Peroneal Nerve Block What to Read Next on Medscape ... Symptomatic relief of compression of the common peroneal nerve (along with the deep peroneal nerve block) ...
When the patient came to our office she has clear evidence of entrapment of these large nerves. We discussed nerve ... This patient is now 2 months from a decompression of the left common peroneal nerve, superficial peroneal nerve, deep peroneal ... We discussed treatment options that centered around nerve decompression surgery of the affected nerves. Within a few weeks, her ... nerve, and sural nerves for severe persistent refractory pain in the left leg with some associated weakness in the ankle. She ...
Antibiotic ear Related Peroneal nerve palsy seen in social media and in the FDA adverse event database. ...
The peroneal nerve was extremely scarred to the surrounding tissue and extensive, meticulous common peroneal neurolysis was ... Motor function in the distribution of the common peroneal nerve was absent. Sensation in the distribution of the deep and ... In this case, despite complete palsy of the common peroneal nerve following the injury, the patient had near full motor ... superficial peroneal nerves was decreased, but the patient could detect light touch in those distributions. Tibial nerve motor ...
Nerve from our Lower Extremity unit. Sketchy Medical helps you learn faster and score higher on the USMLE Step 1 and Step 2 ... Watch a free lesson about Common Peroneal (Fibular) ... the superficial peroneal nerve and the deep peroneal nerve. The ... the superficial peroneal nerve and the deep peroneal nerve. The superficial peroneal nerve is responsible for providing ... What is the common peroneal nerve and where is it located?. The common peroneal nerve, also known as the fibular nerve, is a ...
The common peroneal nerve is a major nerve that supplies the lower limb. The common peroneal nerve is the smaller and terminal ...
The most common nerve injured with a knee dislocation is the peroneal nerve. Nerve injury can result in severe functional ... The most common nerve injured with a knee dislocation is the peroneal nerve. Nerve injury can result in severe functional ... The most common nerve injured with a knee dislocation is the peroneal nerve. Nerve injury can result in severe functional ... The most common nerve injured with a knee dislocation is the peroneal nerve. Nerve injury can result in severe functional ...
Filed under: AMICUS, anatomy, foot, muscles, inversion, eversion, turn, nerve, innervation, peroneal, fibularis, cutaneous, ...
Common Peroneal Nerve release in a 50 yo female. Foot drop started due to rapid weight loss. Patient was referred by a Spine ... Common Peroneal Nerve release in a 50 yo female. Foot drop started due to rapid weight loss. Patient was referred by a Spine ... Common Peroneal Nerve Release in a 50 yo Female November 27, 2020. bywil-adams-dpm ... Common Peroneal Nerve Release in a 50 yo Female. November 27, 2020. bywil-adams-dpm ...
div class=csl-bib-body, ,div class=csl-entry,Schlaff, C. (2014). ,i,Conditioning effect of peroneal nerve stimulation on ... Conditioning effect of peroneal nerve stimulation on the transcutaneously elicited posterior root-muscle reflex ... We conducted our measurements on five subjects with intact nervous systems . One-second conditioning trains of peroneal nerve ... We tested the effects of trains of peroneal nerve stimulation. The modifications of monosynaptically evoked lumbosacral ...
Thickened peripheral nerves (ulnar, radial, peroneal). *Loss of eyebrows. *Thickening of earlobes ... Hansens disease is an infectious, chronic bacterial disease that primarily affects the skin and peripheral nerves. Specific ...
Fabella Syndrome of Bilateral Knee with Common Peroneal Nerve Compression Neuropathy Total Views: 82 , Total Downloads: 86 ... Knee pain; fabella; neuropathy; common peroneal nerve. Abstract. Fabella syndrome is a rare, often underdiagnosed cause of ... It can disrupt the common peroneal nerve because of its anatomical location at the lateral head of the gastrocnemius at the ... 2022). Fabella Syndrome of Bilateral Knee with Common Peroneal Nerve Compression Neuropathy. Malaysian Journal of Science ...
Patient Problems Pain (1994); Peroneal Nerve Palsy (2362); Disability (2371) Event Type Injury ... It was reported the patient experienced severe pain and disability secondary to post operative radial nerve palsy. The event ...
Left peroneal nerve. Ankle-extensor digitorum brevis. 5.1 (reference ,5.5). 1.061 (reference ,2). 35 (reference ,42). Not ... Right peroneal nerve. Ankle-extensor digitorum brevis. 3.8 (reference ,5.5). 1.947 (reference ,2). 33 (reference ,42). Not ... Left tibial nerve. Ankle-abductor hallucis brevis. 6.5 (reference ,5.1). 0.825 (reference ,4). 38 (reference ,40). 51.4 ( ... Right tibial nerve. Ankle-abductor hallucis brevis. 6.3 (reference ,5.1). 5.4 (reference ,4). 39 (reference ,40). 49.4 ( ...
Superficial Peroneal Nerve Entrapment in Female Collegiate Tennis Athlete: A Disablement Model Case Study Authors. * Sarah ... The findings, along with the clinical presentation were consistent with superficial peroneal nerve (SPN) entrapment. Following ...
Quantitation of axon loss and conduction block in peroneal nerve palsies. Watson BV, Brown WF ... Over 3500 patients are studied in the EMG laboratory each year with a full variety of studies ranging from simple nerve ...
NMES was applied to the right part of the common peroneal nerve for 20 min. The stimulation intensity was 95% of the motor ... Koseki, T., Kudo, D., Katagiri, N. et al. Electrical stimulation of the common peroneal nerve and its effects on the ... NMES was applied to the right part of the common peroneal nerve for 20 min. The stimulation intensity was 95% of the motor ... Electrical stimulation of the common peroneal nerve and its effects on the relationship between corticomuscular coherence and ...
Conclusion: Posterior leaf Spring AFO is more effective design for Persons with Drop foot (Peroneal nerve injury) as compare to ... Sheffler, L. R., Hennessey, M. T., Naples, G. G., & Chae, J. (2006). Peroneal nerve stimulation versus an ankle foot orthosis ... Purpose: Comparing the effect of leaf spring and Swedish AFO in patient with drop foot deformity (Peroneal nerve injury). ... de Bruijn, I. L., Geertzen, J. H., & Dijkstra, P. U. (2007). Functional outcome after peroneal nerve injury. International ...
  • PNS effects were evaluated in the ulnar and peroneal nerves using measurements of maximum motor nerve conduction velocity and distal latency. (cdc.gov)
  • Electrodiagnostics performed on hospital day 7 demonstrated reduced motor and sensory amplitudes on right median and ulnar nerves, reduced motor amplitudes, and mildly reduced conduction velocities in the right peroneal nerve and right posterior tibial nerves. (cdc.gov)
  • Subjects were examined for neuropathy, and nerve conduction was measured at the peroneal motor nerve, sural sensory nerve, and ulnar sensory and motor nerves. (cdc.gov)
  • Peroneal nerve paralysis is a paralysis on common fibular nerve that affects patient's ability to lift the foot at the ankle. (wikipedia.org)
  • Peroneal nerve is most commonly interrupted at the knee and possibly at the joint of hip and ankle. (wikipedia.org)
  • The deep peroneal nerve is responsible for lifting up the toe and ankle. (healthline.com)
  • This means any injury to this nerve causes ankle and toe weakening along with numbness between the big toe and second toe. (healthline.com)
  • Deep peroneal nerve block is one of the 2 deep nerve blocks at the level of the ankle. (medscape.com)
  • The deep peroneal nerve block is easy to perform and may constitute part of an ankle block. (medscape.com)
  • [ 1 , 2 ] In the distal one third of the ankle, the nerve is located between the tibialis anterior and extensor hallucis longus muscles and is superficial to the anterior tibial artery. (medscape.com)
  • At an average distance of 12.5 mm proximal to the ankle, the nerve crosses deep to the extensor hallucis longus tendon and courses between the extensor hallucis longus and extensor digitorum longus tendons. (medscape.com)
  • Treatment of acute or chronic pain conditions involving the foot with entrapment of the deep peroneal nerve at the anterior tarsal tunnel (Anterior tarsal tunnel syndrome is characterized by persistent aching of the dorsum of the foot that is worse at night and is made better by moving the affected toes and ankle. (medscape.com)
  • S1, S2) Common Fibular (Peroneal) Nerve,The Ankle and Foot Nov 26, 2009 I had peroneal nerve decompression surgery but doc was unable to reach tib/fib cyst without splitting my calf open. (firebaseapp.com)
  • Entrapment of the tibial nerve or one of its branches gives rise to tarsal tunnel syndrome , which is the most common entrapment neuropathy in the foot and ankle area. (medscape.com)
  • At the level of ankle, the superficial peroneal nerve splits to fan out between the medial and lateral malleoli. (medscape.com)
  • As part of an ankle block required to manipulate a fracture or dislocated ankle (A combination of posterior tibial, saphenous, superficial peroneal, deep peroneal, and sural nerve blocks results in complete block of sensory perception beneath the ankle. (medscape.com)
  • This block requires anesthetization of 5 nerves for complete sensory block below the ankle. (medscape.com)
  • The areas to anesthetize include a line along the anterior ankle for the superficial peroneal nerve (blue line), the deep peroneal nerve (red star), the saphenous nerve (pink star), the sural nerve (green arrow), and the posterior tibial nerve (orange arrow). (medscape.com)
  • This patient is now 2 months from a decompression of the left common peroneal nerve, superficial peroneal nerve, deep peroneal nerve, and sural nerves for severe persistent refractory pain in the left leg with some associated weakness in the ankle. (baltimoreperipheralnervepain.com)
  • This injury was bad enough to cause a "stretch" traction type of injury to the ankle and leg most likely leading to a damaged nerve that was healthy enough to function… "sort of. (baltimoreperipheralnervepain.com)
  • So if you have had an lower extremity ankle injury, or knee injury that has "completely healed," but continue to experience life-limiting pain in the foot and ankle, then we would be delighted to evaluate your lower extremity for possible peripheral nerve injuries or entrapments that can be overlooked at times by other teams. (baltimoreperipheralnervepain.com)
  • Kinematic and kinetic benefits of implantable peroneal nerve stimulation in people with post-stroke drop foot using an ankle-foot orthosis. (poltekkesjakarta1.ac.id)
  • Often, peroneal nerve injuries develop because of a traumatic injury to your knee, leg or ankle. (clevelandclinic.org)
  • O'Malley can not dorsiflex his right foot due to the momentary nerve injury which then causes him to roll his right ankle later. (sportskeeda.com)
  • The common peroneal nerve is a branch of the sciatic nerve. (medlineplus.gov)
  • The common peroneal nerve runs alongside the sciatic nerve, from the femur to the buttocks. (healthline.com)
  • Feels more anterior than May 19, 2017 The common peroneal nerve Palsy: is a nerve in the lower leg that provides sensation and motor function When damaged or compressed Sciatic Nerve Glide. (firebaseapp.com)
  • This is "Supine Sciatic Nerve Glide with Peroneal Emphasis" by Keet Health on Vimeo, the home for high quality videos and the people who love them. (firebaseapp.com)
  • The common peroneal nerve, also known as the fibular nerve, is a branch of the sciatic nerve that wraps around the neck of the fibula. (sketchy.com)
  • The proximal tibia l nerve arises from the sciatic nerve just proximal to the knee joint . (kneeguru.co.uk)
  • It is a branch of the sciatic nerve, passing through the popliteal fossa at the back of the knee on its way to the side of the lower leg and the foot and sole. (kneeguru.co.uk)
  • It's a branch of the sciatic nerve that travels from the back of your thigh along the outside of your knee to the front of your lower leg. (clevelandclinic.org)
  • Injuries to your sciatic nerve in your buttock or back of your thigh can also cause a foot drop. (clevelandclinic.org)
  • Sciatic nerve transection, early after birth, results in significant degeneration of spinal motoneurons as well as sensory neurons present in the dorsal root ganglia. (hindawi.com)
  • The main objective of the study was to determine the level of bifurcation of the sciatic nerve above the transverse popliteal crease among Ugandans at Mulago Hospital Complex. (bvsalud.org)
  • Conclusions: The Bifurcation of the sciatic nerve occurs at variable distances from the transverse popliteal crease and appreciation of these variations is essential. (bvsalud.org)
  • More than 22of all nerves leave the pelvis as two separate nerves and therefore the sciatic nerve trunk cannot be wholly traced or used for anesthetic block in the gluteal region or thigh for procedures in the leg and foot. (bvsalud.org)
  • The deep peroneal nerve (or the anterior tibial nerve) begins at the bifurcation of the common peroneal nerve, between the fibula and upper part of peroneus longus. (medscape.com)
  • Tibial nerve involvement by adding Eversion and Dorsiflexion (TED) for bias accents. (firebaseapp.com)
  • The tibial nerve is done with the foot pointed and flexed back and forth, with the same knee and hip motions or positions. (firebaseapp.com)
  • Historically, tarsal tunnel syndrome was defined as entrapment of the tibial nerve in the fibro-osseous tunnel behind the medial malleolus, and it was considered rare. (medscape.com)
  • Nevertheless, the term tarsal tunnel syndrome continues to be frequently used to define all entrapments of the tibial nerve or its branches, starting from posterior to the medial malleolus and extending distally. (medscape.com)
  • Tibial nerve motor function and sensation were normal. (medscape.com)
  • Diminished sensation over the sole of the foot, especially on the medial side, is noted, resulting from posterior tibial nerve compression. (medscape.com)
  • The tibial nerve is felt stiffly around the point where the line connecting the endocondyle and calcaneus divides 1:2. (drsashimi.com)
  • Furthermore, evoked spinal reflex responses of the soleus muscle (H-reflex evoked at rest and during iMVC, V-wave), peak twitch torques induced by electrical stimulation of the posterior tibial nerve at rest and fatigue resistance were evaluated. (frontiersin.org)
  • These evoked potentials are elicited by electrical stimulation of the posterior tibial nerve in the popliteal fossa and their amplitudes can be recorded in the soleus muscle (SOL). (frontiersin.org)
  • The tibial nerve and common peroneal nerve (also known as common fibular nerve) originate at L5, S1 and S2. (physio-pedia.com)
  • The tibial nerve provides motor fibres to gastrocnemius, soleus, tibialis posterior, flexor digitorum longus, and flexor hallucis longus. (physio-pedia.com)
  • Inflammatory pseudotumors of the peripheral nerves, although rare, should always be of consideration in the differential diagnosis of peripheral nerve nodular mass lesions. (qxmd.com)
  • They can mimic neoplastic nerve sheath lesions, clinically and radiologically. (qxmd.com)
  • This is not surprising given the strong evidence for interaction between myelin and axon gene expression in development and after experimental nerve lesions. (medscape.com)
  • Two patients developed temporary superficial peroneal nerve lesions. (aott.org.tr)
  • There was no objective sensory finding and no cranial nerve lesions. (who.int)
  • There was no objective sensory increased to 23 kg/m², he recovered finding and no cranial nerve lesions. (who.int)
  • 2021-02-23 · Although peroneal nerve surgery can be very helpful in cases of damage to both the superior and superficial peroneal nerves, it is so important to catch this kind of thing early. (firebaseapp.com)
  • Sensation in the distribution of the deep and superficial peroneal nerves was decreased, but the patient could detect light touch in those distributions. (medscape.com)
  • Examinations are required for following reasons: Considering lumbar radiculopathy during the examination Possibility of foot drop Sensory loss that may be difficult to determine because of variable and small autonomous zone of sensation Tinel's sign over the fibular neck that can help localize the site of nerve compression Checking for direct compression that reproduces nerve symptoms Electromyography is used to observe peroneal nerve palsy within one month of injuries. (wikipedia.org)
  • Nerve conduction studies and electromyography are very useful in finding where the nerve problem is. (clevelandclinic.org)
  • Electromyography demonstrated impairment of bilateral peroneal nerve function: evoked amplitude was markedly reduced, with slight slowing of nerve conduction velocity. (who.int)
  • Dysfunction of a single nerve such as the common peroneal nerve is called a mononeuropathy. (wikipedia.org)
  • Common peroneal nerve dysfunction is due to damage to the peroneal nerve leading to loss of movement or sensation in the foot and leg. (medlineplus.gov)
  • This condition is also called common fibular nerve dysfunction. (medlineplus.gov)
  • Common peroneal nerve dysfunction is a type of peripheral neuropathy (nerve damage outside the brain or spinal cord). (medlineplus.gov)
  • Other tests may be done depending on the suspected cause of nerve dysfunction, and the person's symptoms and how they develop. (medlineplus.gov)
  • Successfully treating the cause may relieve the dysfunction, but it may take several months for the nerve to improve. (medlineplus.gov)
  • Treatment of peroneal nerve dysfunction starts by treating the underlying cause of the condition. (firebaseapp.com)
  • Injury or entrapment of the lateral femoral cutaneous nerve, also known as meralgia paresthetica (from the Greek words mēros ["thigh"] and algos ["pain"]), is a syndrome of paresthesia and pain in the lateral and anterolateral thigh. (medscape.com)
  • In time, however, the lateral plantar nerve and its branches were noted to be a more common site of entrapment. (medscape.com)
  • [ 3 ] interdigital neuroma, Morton metatarsalgia, or interdigital nerve compression-results from entrapment of a plantar interdigital nerve as it passes under the transverse metatarsal ligament. (medscape.com)
  • When the patient came to our office, she had clear evidence of entrapment of these large nerves. (baltimoreperipheralnervepain.com)
  • The findings, along with the clinical presentation were consistent with superficial peroneal nerve (SPN) entrapment. (indstate.edu)
  • Compression of nerves in narrow passageways causes entrapment neuropathy (eg, in carpal tunnel syndrome). (msdmanuals.com)
  • Training and orthotic effects related to functional electrical stimulation of the peroneal nerve in stroke. (bournemouth.ac.uk)
  • PURPOSE: To investigate the efficiency of electrical stimulation in the muscle maintenance and nerve regeneration after end-to-side neurorrhaphy (ESN). (unesp.br)
  • CONCLUSION: Electrical stimulation is an effective means of maintaining functional muscle and nerve regeneration after end-to-side neurorrhaphy. (unesp.br)
  • Stimulation of the peripheral nerve allows targeting these networks to alter their excitability. (tuwien.at)
  • We tested the effects of trains of peroneal nerve stimulation. (tuwien.at)
  • One-second conditioning trains of peroneal nerve stimulation with a frequency of 15, 30 and 50 Hz were applied at 0.8, 1.2 and 1.5 times the motor threshold. (tuwien.at)
  • There was a significant reduction in the ratio of amplitudes of muscle action potentials measured during peroneal nerve stimulation. (cdc.gov)
  • The superficial peroneal nerve provides sensory innervation to the dorsum of the foot, excluding the webspace between the hallux and the 2nd toe, and motor innervation to the lateral compartment muscles of the leg√ëthe peroneus longus and peroneus brevis√ëresponsible for foot eversion. (sketchy.com)
  • A defining feature of common peroneal nerve injury is steppage or equine gait , which manifests as foot drop, leading to impaired foot dorsiflexion and eversion. (sketchy.com)
  • This is often due to an injury to the common peroneal nerve and results from paralysis in the muscles responsible for dorsiflexion and eversion of the foot. (sketchy.com)
  • One year after surgery, he had normal, symmetrical peroneal eversion strength with slight weakness of dorsiflexion power on the left. (medscape.com)
  • Peroneal nerve palsy causes footdrop (weakened dorsiflexion and eversion of the foot) and, occasionally, a sensory deficit in the anterolateral aspect of the lower leg and the dorsum of the foot or in the web space between the 1st and 2nd metatarsals. (msdmanuals.com)
  • Peroneal nerve paralysis usually leads to neuromuscular disorder, peroneal nerve injury, or foot drop which can be symptoms of more serious disorders such as nerve compression. (wikipedia.org)
  • The origin of peroneal nerve palsy has been reported to be associated with musculoskeletal injury or isolated nerve traction and compression. (wikipedia.org)
  • Peroneal nerve injury occurs when the knee is exposed to various stress. (wikipedia.org)
  • Since it is wound around the fibula, a break or damage to this bone can also result in an injury to the common peroneal nerve. (firebaseapp.com)
  • Nerve injury occurs most commonly as a complication of surgical procedures involving the lower abdomen. (medscape.com)
  • What makes the common peroneal nerve prone to injury? (sketchy.com)
  • Multi-ligament knee injury is a complex and difficult injury to manage, particularly when there are associated nerve or vascular injuries. (medscape.com)
  • In this case, despite complete palsy of the common peroneal nerve following the injury, the patient had near full motor recovery. (medscape.com)
  • Nerve injury can result in severe functional consequences to the injured patient. (elsevierpure.com)
  • Relationship between fabella and posterolateral knee pain and common peroneal nerve injury. (usim.edu.my)
  • Methodology: Four (4) participants with Drop Foot (Peroneal nerve injury) were selected through simple random sampling and they were allowed to walk at their self-selected speed with Swedish AFO and with PLS AFO in order to compare their controlling of Planter Flexion at Initial Contact and at Mid Swing under experimental design. (poltekkesjakarta1.ac.id)
  • Conclusion: Posterior leaf Spring AFO is more effective design for Persons with Drop foot (Peroneal nerve injury) as compare to Swedish AFO. (poltekkesjakarta1.ac.id)
  • Functional outcome after peroneal nerve injury. (poltekkesjakarta1.ac.id)
  • The most common causes are peroneal nerve injury and lumbar radiculopathy. (clevelandclinic.org)
  • Peroneal nerve injury is a common cause of the symptom. (clevelandclinic.org)
  • Experimentally, a well-accepted model to mimic axotomy injury retrograde repercussion to spinal neurons is the neonatal peripheral nerve axotomy [ 13 - 18 ]. (hindawi.com)
  • We report a case of West Nile poliomyelitis with preserved deep-tendon reflexes, diminished sensory nerve action potentials, and pathologic findings which do not localize to the anterior horn. (cdc.gov)
  • Causing factors of peroneal nerve palsy are such as musculoskeletal or peroneal nerve injuries. (wikipedia.org)
  • However, certain conditions may also cause single nerve injuries. (wikipedia.org)
  • Certain body-wide conditions can also cause single nerve injuries. (medlineplus.gov)
  • Regional block of the superficial peroneal nerve allows for rapid anesthetization of the dorsum of the foot, which allows for management of lacerations, fractures, nail bed injuries, or other pathology involving the dorsum of the foot. (medscape.com)
  • In the upper arm and near the shoulder, the median nerve branches off of the brachial plexus. (healthline.com)
  • Transient forearm conduction block in the median nerve. (lhsc.on.ca)
  • It results from compression of the median nerve in the volar aspect of the wrist between the transverse superficial carpal ligament and the flexor tendons of the forearm muscles. (msdmanuals.com)
  • The results of median sensory-motor, sural sensory and post-tibial motor nerve conduction studies were normal. (who.int)
  • The results antituberculosis pharmacotherapy is had no history of immunodeficiency, of median sensory-motor, sural sen- relatively uncommon, although the fre- no diabetes, no renal failure, no hepatic sory and post-tibial motor nerve con- quency of the usage of antituberculosis failure, no HIV infection and he was a duction studies were normal. (who.int)
  • hence the need for healthcare workers to have adequate appreciation of the applied anatomy of the nerve. (bvsalud.org)
  • Relatively tethered location around fibular head, tenuous vascular supply and epineural connective tissues are possible factors that cause damage on the common peroneal nerve. (wikipedia.org)
  • Common peroneal nerve is a type of mononeuropathy . (medlineplus.gov)
  • The deep peroneal nerve makes up one section of the common peroneal nerve. (healthline.com)
  • The common peroneal nerve (root values: L4, L5, S1, and S2) winds around the fibula through the fibular tunnel. (medscape.com)
  • 5. Education My daily treatment to give you an idea how to treat common peroneal nerve tension: Nerve glides (also known as neural flossing or nerve stretching) are exercises that aim to restore mobilization of our peripheral nerves. (firebaseapp.com)
  • The superficial peroneal nerve arises from the common peroneal nerve, which also gives rise to the deep peroneal nerve. (medscape.com)
  • The common peroneal nerve , also termed the fibular nerve, courses around the neck of the fibula and splits into two primary branches: the superficial peroneal nerve and the deep peroneal nerve . (sketchy.com)
  • The common peroneal nerve is the most frequently injured nerve in the lower extremity . (sketchy.com)
  • What is the common peroneal nerve and where is it located? (sketchy.com)
  • The peroneal nerve, also known as the common fibular nerve, bifurcates into two main branches: the superficial peroneal nerve and the deep peroneal nerve. (sketchy.com)
  • The common peroneal nerve is the most commonly injured nerve in the lower extremity, largely because of its vulnerable location around the neck of the fibula. (sketchy.com)
  • What is 'foot drop' and how does it relate to the common peroneal (fibular) nerve? (sketchy.com)
  • The common peroneal nerve is a major nerve that supplies the lower limb. (samarpanphysioclinic.com)
  • Motor function in the distribution of the common peroneal nerve was absent. (medscape.com)
  • During the same procedure, another surgeon (AD) performed neurolysis of the common peroneal nerve. (medscape.com)
  • The peroneal nerve was extremely scarred to the surrounding tissue and extensive, meticulous common peroneal neurolysis was performed. (medscape.com)
  • The most common nerve injured with a knee dislocation is the peroneal nerve. (elsevierpure.com)
  • It can disrupt the common peroneal nerve because of its anatomical location at the lateral head of the gastrocnemius at the lateral femoral condyle, where the nerve typically passes. (usim.edu.my)
  • Failure to adequately identify a common peroneal nerve neuropathy associated with fabella syndrome can lead to recurrent visits, unnecessary examinations, and surgical procedures. (usim.edu.my)
  • Compression neuropathy of the common peroneal nerve by the fabella. (usim.edu.my)
  • Influence of a fabella in the gastrocnemius muscle on the common fibular nerve in Japanese subjects. (usim.edu.my)
  • NMES was applied to the right part of the common peroneal nerve for 20 min. (biomedcentral.com)
  • Your common peroneal nerve is a peripheral nerve that extends down your leg. (clevelandclinic.org)
  • Several things can damage your common peroneal nerve and cause foot drop. (clevelandclinic.org)
  • The superficial branch of the common peroneal nerve sends motor fibres to peroneus (fibularis) longus and brevis. (physio-pedia.com)
  • The ilioinguinal nerve branches off the first lumbar nerve, which is near the lower back. (healthline.com)
  • In the leg, the deep peroneal nerve supplies muscular branches to the tibialis anterior, extensor digitorum longus, peroneus tertius, and extensor hallucis longus. (medscape.com)
  • From the enlargement, 3 minute interosseous branches (dorsal interosseous nerves) are given off, which supply the tarsal joints and the metatarsophalangeal joints of the 2nd, 3rd, and 4th toes. (medscape.com)
  • The superficial peroneal nerve provides motor function to peroneous longus and brevis, but also gives off sensory branches that provide feeling to the skin across the top of most of your feet. (firebaseapp.com)
  • motor 2016-08-11 The peroneal nerve is also located at the back of the fibula, at the top of it, and winds around it where it breaks off into two branches, the superficial and deep peroneal nerves. (firebaseapp.com)
  • The genitofemoral nerve or its branches (genital or femoral) can be entrapped throughout its course. (medscape.com)
  • The nerve supplies the lower fibers of the transversus abdominis and the internal oblique muscle and divides into lateral and anterior cutaneous branches. (medscape.com)
  • After winding around the fibula, the nerve further divides into two main branches: the superficial peroneal nerve and the deep peroneal nerve, each responsible for specific sensory and motor activities. (sketchy.com)
  • What are the superficial and deep branches of the Peroneal Nerve? (sketchy.com)
  • Active function in the other muscles innervated by the deep and superficial branches of the peroneal nerve essentially rules out the possibility of a peripheral neuropathy. (medscape.com)
  • Radiculopathy happens when one of your nerve roots (where your nerves join your spinal column) is compressed or irritated. (clevelandclinic.org)
  • Your peroneal nerve is a peripheral nerve (nerves outside your brain and spinal cord). (clevelandclinic.org)
  • It includes the cranial nerves and spinal nerves from their origin to their end. (msdmanuals.com)
  • Spinal nerve roots demonstrated focal lymphocytic inflammation within the endoneurial compartment. (cdc.gov)
  • The peroneal nerve is a sensory nerve in the lower extremity, and is therefore very susceptible to neuropathy and edema. (drsashimi.com)
  • For this reason, the peroneal nerve is the most frequently affected by neuropathy and edema. (drsashimi.com)
  • Any condition that affects peripheral nerves, such as Charcot-Marie-Tooth disease or acquired peripheral neuropathy , can affect your peroneal nerve and cause foot drop. (clevelandclinic.org)
  • In the late 1960s, neurophysiologic testing allowed the classification of CMT into 2 groups, one with slow nerve conduction velocities and histologic features of a hypertrophic demyelinating neuropathy (hereditary motor and sensory neuropathy type 1 or CMT1) and another with relatively normal velocities and axonal and neuronal degeneration (hereditary motor and sensory neuropathy type 2 or CMT2). (medscape.com)
  • The diagnosis of GBS is clinical but may be aided by electrophysiology which is also important to characterise the two main electrophysiological subtypes: acute inflammatory demyelinating polyradiculoneuropathy (AIDP), which is sensory and motor and displays demyelinating changes on nerve conduction studies, and acute motor axonal neuropathy (AMAN), which is primarily axonal and thought to be purely motor. (bmj.com)
  • Hemorrhage that compresses a nerve, exposure to cold or radiation, or direct tumor invasion may also cause neuropathy. (msdmanuals.com)
  • Only one subject, a diabetic, had both abnormal nerve velocities and signs of neuropathy. (cdc.gov)
  • The authors conclude that nerve conduction velocities are insensitive in screening for subclinical neuropathy in subjects exposed to inorganic arsenic. (cdc.gov)
  • Se hela listan på physio-pedia.com 2018-02-05 · Peroneal nerve or fibular nerve is the one of the two parts of sciatica nerve that is found below the knee joint. (firebaseapp.com)
  • The effects of arsenic (7440382) on nerve conduction velocities were studied in Alaskan residents with naturally contaminated drinking water. (cdc.gov)
  • One or more nerve conduction velocities were abnormal in 13 subjects, but nerve velocity measurements were not related to estimated daily arsenic ingestion or arsenic concentrations in water or urine. (cdc.gov)
  • The nerve then splits inside the neck of the fibula into two parts: the deep peroneal nerve and the superficial peroneal nerve. (healthline.com)
  • The superficial nerve simply sits closer to the skin than the deep nerve, but they each connect to different muscles and tissue. (healthline.com)
  • The deep peroneal nerve block is useful for anesthesia and postoperative analgesia to surgeries of the first web space (eg, Morton neuroma ). (medscape.com)
  • Just distal to the fibular tunnel, the nerve divides into the superficial and deep peroneal nerves. (medscape.com)
  • Deep peroneal nerve and adjacent structures. (medscape.com)
  • The deep peroneal branch continues into the foot along with the tibial artery and the vein. (medscape.com)
  • As a prelude to neurolysis or radiofrequency ablation of the deep peroneal nerve. (medscape.com)
  • Deep Peroneal n. glides Hello, I'm a first-year Podiatry student and I'm interested in reading up on some deep peroneal nerve glides, but when I try to look for them I find peroneal nerve glides or superficial peroneal nerve glides. (firebaseapp.com)
  • Toenail repair (Toenail repair on the lateral first digit and medial second digit also requires deep peroneal nerve block. (medscape.com)
  • The deep peroneal nerve provides sensation to the webspace between the hallux and 2nd toe and motor innervation to the anterior compartment muscles of the leg, including the tibialis anterior, extensor hallucis longus, and extensor digitorum longus, thereby enabling foot dorsiflexion and toe extension. (sketchy.com)
  • The deep peroneal nerve supplies sensation to the webspace between the hallux and second toe, and innervates muscles of the anterior compartment of the leg such as the tibialis anterior, extensor hallucis longus, and extensor digitorum longus, facilitating foot dorsiflexion and toe extension. (sketchy.com)
  • Clinical presentation of an acute anterior compartment syndrome includes pain with passive toe flexion, some weakness of toe extension, and diminished sensation in the first web space because of deep peroneal nerve compression. (medscape.com)
  • Deep peroneal nerve (L4, L5, S1). (getbodysmart.com)
  • occasionally supply the area typically innervated by the deep peroneal nerve. (physio-pedia.com)
  • Between it and the tibialis anterior are the upper portions of the anterior tibial vessels and deep peroneal nerve. (wikipedia.org)
  • At the first interosseous space, it divides into dorsal digital nerves, which provide sensory innervation to the first webspace and the adjacent dorsum of the foot. (medscape.com)
  • The nerve splits into the medial dorsal cutaneous nerve and the intermediate dorsal cutaneous nerve, which give rise to the dorsal digital nerves. (medscape.com)
  • In addition, others have more specifically identified entrapments involving the first branch of the lateral plantar nerve and the calcaneal nerves. (medscape.com)
  • The iliohypogastric nerve traverses the psoas major, piercing the lateral border of the muscle anterior to the quadratus lumborum and posterior to the kidney to traverse the lateral abdominal wall. (medscape.com)
  • However, this nerve does not supply the web space between the first and second digits or the lateral fifth digit. (medscape.com)
  • and from the intermuscular septa between it and the tibialis anterior on the medial, and the peroneal muscles on the lateral side. (wikipedia.org)
  • Peroneal nerve palsy is usually caused by compression of the nerve against the lateral aspect of the fibular neck. (msdmanuals.com)
  • These findings suggested a predominantly axonal polyneuropathy involving both sensory and motor nerves. (cdc.gov)
  • The superficial peroneal nerve originates between the peroneus longus muscle and the fibula. (medscape.com)
  • There might be a loss of feeling, muscle control, muscle tone, and eventual loss of muscle mass because the nerves aren't stimulating the muscles after they are damaged. (wikipedia.org)
  • The accessory nerve is a cranial nerve that controls the movement of certain neck muscles. (healthline.com)
  • It runs anterolateral to the fibula between the peroneal muscles and the extensor digitorum longus, eventually supplying the peroneal muscles. (medscape.com)
  • Foot drop has several possible causes, typically due to an issue with your nerves and/or muscles. (clevelandclinic.org)
  • Damages on peroneal nerves destroy the myelin sheath that covers the axon or the whole nerve cell. (wikipedia.org)
  • Damage to the nerve disrupts the myelin sheath that covers the axon (branch of the nerve cell). (medlineplus.gov)
  • The vagus nerve is the longest of the 12 cranial nerves. (healthline.com)
  • The oculomotor nerve is the third of 12 pairs of cranial nerves in the brain. (healthline.com)
  • Distal latency, residual latency, and muscle or nerve action potential amplitudes did not differ significantly in the study groups. (cdc.gov)
  • These nerves supply the skin of the anterolateral distal third of the leg, most of the dorsal foot, and the digits. (medscape.com)
  • This time, we will focus on three typical nerves in the lower limb. (drsashimi.com)
  • Peroneal nerve in continuity arises from defined cause will be recovered better than those arise from unknown causes. (wikipedia.org)
  • The iliohypogastric nerve arises primarily from the ventral primary rami of L1 and occasionally with a twig from T12. (medscape.com)
  • It was reported the patient experienced severe pain and disability secondary to post operative radial nerve palsy. (fda.gov)
  • Examination revealed a thickening in the posterolateral aspect of the popliteal fossa and features consistent with peroneal nerve palsy. (qxmd.com)
  • This allows us to examine the peroneal head, where the peroneal nerve is most likely to be injured, when we next stimulate the popliteal fossa. (drsashimi.com)
  • The anterior cutaneous branch of the iliohypogastric nerve continues anteriorly between the internal oblique muscle and the transversus abdominis, then pierces the internal oblique muscle and becomes cutaneous through an opening in the fascial aponeurosis of the external oblique muscle, approximately 2-3 cm cephalad to the superficial inguinal ring. (medscape.com)
  • Superficial peroneal nerve dermatome at the level of the anterior lower leg. (medscape.com)
  • If the symptom does not get any better in few months, surgery is required to decompress the nerve compression. (wikipedia.org)
  • Compression of a nerve may be transient (eg, caused by an activity) or fixed (eg, caused by a mass or anatomic abnormality). (msdmanuals.com)
  • The superficial peroneal nerve is responsible for providing sensation to the dorsum of the foot, except for the webspace between the hallux and the second toe. (sketchy.com)