Mole Rats
Moles
Hydatidiform Mole
Rodent Diseases
Blindness
Disease Resistance
Hydatidiform Mole, Invasive
Species Specificity
Skin morphology and its role in thermoregulation in mole-rats, Heterocephalus glaber and Cryptomys hottentotus. (1/116)
The skin structure of 2 Bathyergid rodents, the naked mole-rat (Heterocephalus glaber) and the common mole-rat (Cryptomys hottentotus) is compared, to investigate whether thermoregulatory differences may be attributed to different skin features. Histological and ultrastructural studies of the dorsal skin of these closely related species show morphological and structural similarities but differences in the degree of skin folding, thickness of the integument and dermal infrastructure were evident. The skin of the common mole-rat conforms with expected morphological/histological arrangements that are commonly found in mammalian skin. Many features of the skin of the naked mole-rat, such as the lack of an insulating layer and the loosely folded morphological arrangement contribute to poikilothermic responses to changing temperatures of this mammal. Further evidence for poikilothermy in the naked mole-rat is indicated by the presence of pigment containing cells in the dermis, rather than the epidermis, as commonly occurs in homeotherms. Lack of fur is compensated by a thicker epidermal layer and a marked reduction in sweat glands. Differences in skin morphology thus contribute substantially to the different thermoregulatory abilities of the 2 Bathyergids. The skin morphology is related to the poor thermoinsulatory ability of the animals while simultaneously facilitating heat transfer from the environment to the animal by thigmothermy and/or other behavioural means. (+info)Adaptive hypoxic tolerance in the subterranean mole rat Spalax ehrenbergi: the role of vascular endothelial growth factor. (2/116)
Spalax ehrenbergi has evolved adaptations that allow it to survive and carry out normal activities in a highly hypoxic environment. A key component of this adaptation is a higher capillary density in some Spalax tissues resulting in a shorter diffusion distance for oxygen. Vascular endothelial growth factor (VEGF) is an angiogenic factor that is critical for angiogenesis during development and in response to tissue ischemia. We demonstrate here that VEGF expression is markedly increased in those Spalax tissues with a higher capillary density relative to the normal laboratory rat Rattus norvegicus. Upregulation of VEGF thus appears to be an additional mechanism by which Spalax has adapted to its hypoxic environment. (+info)Circadian biology: clocks for the real world. (3/116)
The circadian system of Neurospora crassa includes a molecular feedback loop that is entrainable by light. A recent study has shown that a second, elusive oscillator interacts with the feedback loop to drive output rhythms. (+info)Spectral tuning of a circadian photopigment in a subterranean 'blind' mammal (Spalax ehrenbergi). (4/116)
The atrophied subcutaneous eyes of Spalax ehrenbergi (the blind mole rat) express a long wavelength sensitive (LWS) cone opsin. Our data provide strong evidence that this photopigment is spectrally tuned to enhance photon capture in the red light environment of the eye. Furthermore, novel mechanisms appear partially responsible for this sensory fine-tuning. These data support the hypothesis that the LWS opsin of Spalax acts as a functional photopigment and that it is not a 'residue' of the pre-subterranean visual system. As the eye of Spalax has only one known function, the entrainment of circadian rhythms to environmental light, the LWS photopigment is implicated in this task. These results, together with our recent findings that rod and cone photopigments are not required for murine photoentrainment, suggest that multiple photopigments (classical and novel) mediate the effects of light on the mammalian circadian system. (+info)Kin discrimination and female mate choice in the naked mole-rat Heterocephalus glaber. (5/116)
Naked mole-rats are fossorial, eusocial rodents that naturally exhibit high levels of inbreeding. Persistent inbreeding in animals often results in a substantial decline in fitness and, thus, dispersal and avoidance of kin as mates are two common inbreeding avoidance mechanisms. In the naked mole-rat evidence for the former has recently been found. Here we address the latter mechanism by investigating kin recognition and female mate choice using a series of choice tests in which the odour, social and mate preferences of females were determined. Discrimination by females appears to be dependent on their reproductive status. Reproductively active females prefer to associate with unfamiliar males, whereas reproductively inactive females do not discriminate. Females do not discriminate between kin and non-kin suggesting that the criterion for recognition is familiarity, not detection of genetic similarity per se. In the wild, naked mole-rats occupy discrete burrow systems and dispersal and mixing with non-kin is thought to be comparatively rare. Thus, recognition by familiarity may function as a highly efficient kin recognition mechanism in the naked mole-rat. A preference by reproductively active females for unfamiliar males is interpreted as inbreeding avoidance. These findings suggest that, despite an evolutionary history of close inbreeding, naked mole-rats may not be exempt from the effects of inbreeding depression and will attempt to outbreed should the opportunity arise. (+info)Inbreeding avoidance and reproductive skew in a cooperative mammal. (6/116)
In animal social groups, socially subordinate individuals frequently show low reproductive success or completely fail to breed. This suppression of subordinate reproduction is currently typically attributed to control by dominant individuals. However, subordinates in cooperative groups often lack access to unrelated mates, and an alternative possibility is that their reproduction is limited by inbreeding avoidance. Using the eusocial Damaraland mole-rat Cryptomys damarensis, this paper provides the first experimental evidence, to our knowledge, for this explanation. Subordinate, non-breeding female mole-rats were given access to unrelated mates while remaining in the presence of dominant females, and many became reproductively active soon after unrelated males were introduced. Inbreeding avoidance and the availability of unrelated mates provides a plausible and untested explanation for variation in reproductive skew across animal societies. (+info)Anovulation in non-reproductive female Damaraland mole-rats (Cryptomys damarensis). (7/116)
Within colonies of Damaraland mole-rats (Cryptomys damarensis), anovulation in non-reproductive females is thought to play an important role in maintaining reproductive skew. Pituitary sensitivity and ovarian structure were examined in three groups of females that differed with respect to their social environment and breeding status to determine whether anovulation is due to inhibitory social cues or is merely the result of a lack of copulatory stimulation. The contribution of gonadal steroid negative feedback to neuroendocrine differences in the reproductive systems of the respective groups was also investigated. LH secretion after a 0.5 micrograms GnRH challenge in females that had been removed from the presence of the breeding individuals for at least 6 months (removed non-reproductive females) was significantly higher than in non-reproductive females in the colony, but significantly lower than in reproductive females. In both removed non-reproductive females and reproductive females, corpora lutea were observed in ovaries of seven of eight females, indicating that ovulation occurs spontaneously in subordinate females on removal from the breeding pair. Circulating progesterone concentrations in removed non-reproductive females were significantly higher than in non-reproductive females, indicating that circulating progesterone is not responsible for infertility in non-reproductive females. Indeed, after hystero-ovariectomy, reproductive females continued to show significantly greater GnRH-stimulated LH secretion than non-reproductive females. Thus, differential inhibition of gonadotrophin secretion in breeding and non-breeding females occurs independently of gonadal steroids. It is concluded that female Damaraland mole-rats are spontaneous ovulators and that anovulation results from inhibitory social cues within the colony, not a lack of copulatory stimulation. Since non-reproductive females are infertile, inhibition of the hypothalamo-pituitary-gonadal axis has the potential to play a causal role in maintaining reproductive skew in colonies of C. damarensis. (+info)A fully functional rod visual pigment in a blind mammal. A case for adaptive functional reorganization? (8/116)
In the blind subterranean mole rat Spalax ehrenbergi superspecies complete ablation of the visual image-forming capability has been accompanied by an expansion of the bilateral projection from the retina to the suprachiasmatic nucleus. We have cloned the open reading frame of a visual pigment from Spalax that shows >90% homology with mammalian rod pigments. Baculovirus expression yields a membrane protein with all functional characteristics of a rod visual pigment (lambda(max) = 497 +/- 2 nm; pK(a) of meta I/meta II equilibrium = 6.5; rapid activation of transducin in the light). We not only provide evidence that this Spalax rod pigment is fully functional in vitro but also show that all requirements for a functional pigment are present in vivo. The physiological consequences of this unexpected finding are discussed. One attractive option is that during adaptation to a subterranean lifestyle, the visual system of this mammal has undergone mosaic reorganization, and the visual pigments have adapted to a function in circadian photoreception. (+info)A mole rat is not a medical term, but a common name for a burrowing rodent that belongs to the family Bathyergidae. There are about 20 species of mole rats, also known as "blind mole rats" or "naked mole rats," depending on the region and scientific classification.
Mole rats are fascinating creatures with several unique biological features. They are primarily subterranean animals, living in complex tunnel systems that they dig with their powerful incisors and sharp claws. Mole rats have reduced eyes or are completely blind, relying instead on their highly developed senses of touch and smell to navigate their environment.
One species, the naked mole rat (Heterocephalus glaber), is particularly well-known for its unusual biology and social behavior. Naked mole rats live in large colonies with a single breeding female (the queen) and multiple males. The queen is the only reproductively active female, while the other members of the colony function as workers, caring for the young and maintaining the burrow system.
Naked mole rats have several remarkable biological traits, including an extraordinarily long lifespan for a rodent (up to 30 years or more) and resistance to cancer. They are also able to survive in low-oxygen environments and exhibit a unique form of social behavior called eusociality, similar to that seen in bees and ants.
While mole rats may not have a direct medical definition, their unique biology has attracted significant scientific interest, leading to important discoveries in fields such as aging, cancer research, and neurobiology.
A mole (nevus) is a benign growth on the skin that is usually brown or black. Moles can appear anywhere on the body, alone or in groups. Most adults have between 10 and 40 moles. They typically appear during childhood and adolescence. Some moles may change over time, possibly becoming raised and/or changing color. It's important to keep an eye on moles and see a healthcare provider if any changes are noticed, as melanoma, a type of skin cancer, can develop from moles.
It is also worth noting that there are different types of moles including congenital nevi (moles present at birth), dysplastic nevi (atypical moles) and acquired nevi (moles that appear after birth). Dysplastic nevi are larger than average and irregular in shape, with color variations. They are more likely to develop into melanoma than regular moles.
A hydatidiform mole, also known as a molar pregnancy, is a type of gestational trophoblastic disease (GTD), which is a group of rare disorders that involve abnormal growth of the placental tissue.
In a hydatidiform mole, there is an abnormal fertilization event leading to the growth of a mass of grapelike cysts in the uterus instead of a normal pregnancy. The chromosomes from the sperm and egg do not combine properly, resulting in an extra set of chromosomes, which leads to the development of the mole.
Hydatidiform moles can be complete or partial:
* Complete hydatidiform mole (CHM): This type arises when an egg without a nucleus is fertilized by one or two sperm, leading to the growth of abnormal placental tissue with no embryo. The chromosomes come from the father only, and there are typically 46 chromosomes, all of paternal origin.
* Partial hydatidiform mole (PHM): This type occurs when an egg is fertilized by two sperm or a single sperm that duplicates itself, resulting in an abnormal placenta with some fetal tissue. The chromosomes are of both maternal and paternal origin, and the placental tissue has a mix of normal and abnormal cells.
Hydatidiform moles can cause vaginal bleeding, rapid uterine enlargement, and high levels of human chorionic gonadotropin (hCG) hormone in the blood. They are usually detected during an ultrasound exam and require medical treatment to prevent complications such as gestational trophoblastic neoplasia, a malignant form of GTD that can spread to other organs.
"Rodentia" is not a medical term, but a taxonomic category in biology. It refers to the largest order of mammals, comprising over 40% of all mammal species. Commonly known as rodents, this group includes mice, rats, hamsters, gerbils, guinea pigs, squirrels, prairie dogs, capybaras, beavers, and many others.
While "Rodentia" itself is not a medical term, certain conditions or issues related to rodents can have medical implications. For instance, rodents are known to carry and transmit various diseases that can affect humans, such as hantavirus, leptospirosis, salmonellosis, and lymphocytic choriomeningitis (LCMV). Therefore, understanding the biology and behavior of rodents is important in the context of public health and preventive medicine.
Rodent-borne diseases are infectious diseases transmitted to humans (and other animals) by rodents, their parasites or by contact with rodent urine, feces, or saliva. These diseases can be caused by viruses, bacteria, fungi, or parasites. Some examples of rodent-borne diseases include Hantavirus Pulmonary Syndrome, Leptospirosis, Salmonellosis, Rat-bite fever, and Plague. It's important to note that rodents can also cause allergic reactions in some people through their dander, urine, or saliva. Proper sanitation, rodent control measures, and protective equipment when handling rodents can help prevent the spread of these diseases.
Blindness is a condition of complete or near-complete vision loss. It can be caused by various factors such as eye diseases, injuries, or birth defects. Total blindness means that a person cannot see anything at all, while near-complete blindness refers to having only light perception or the ability to perceive the direction of light, but not able to discern shapes or forms. Legal blindness is a term used to define a certain level of visual impairment that qualifies an individual for government assistance and benefits; it usually means best corrected visual acuity of 20/200 or worse in the better eye, or a visual field no greater than 20 degrees in diameter.
Contact inhibition is a biological phenomenon primarily observed in cell culture systems, where cells come into contact with each other and stop growing or dividing. This process helps to regulate cell growth and prevent overcrowding, allowing the cells to form a monolayer that covers the surface of the culture dish evenly.
In more detail, when normal animal cells come into contact with neighboring cells during migration or proliferation, they stop growing and dividing, and may even retract their processes or move away from each other. This behavior is thought to be mediated by a variety of mechanisms, including the activation of specific signaling pathways that inhibit cell cycle progression and promote cytoskeletal changes leading to retraction of cellular protrusions.
Contact inhibition plays an important role in maintaining tissue homeostasis and preventing uncontrolled cell growth, which can lead to tumor formation. In some cases, cancer cells may lose contact inhibition, allowing them to continue growing and dividing even when they come into contact with other cells, leading to the formation of tumors and invasive growth patterns.
Disease resistance, in a medical context, refers to the inherent or acquired ability of an organism to withstand or limit infection by a pathogen, such as bacteria, viruses, fungi, or parasites. This resistance can be due to various factors including the presence of physical barriers (e.g., intact skin), chemical barriers (e.g., stomach acid), and immune responses that recognize and eliminate the pathogen.
Inherited disease resistance is often determined by genetics, where certain genetic variations can make an individual more or less susceptible to a particular infection. For example, some people are naturally resistant to certain diseases due to genetic factors that prevent the pathogen from infecting their cells or replicating within them.
Acquired disease resistance can occur through exposure to a pathogen, which triggers an immune response that confers immunity or resistance to future infections by the same pathogen. This is the basis of vaccination, where a weakened or dead form of a pathogen is introduced into the body to stimulate an immune response without causing disease.
Overall, disease resistance is an important factor in maintaining health and preventing the spread of infectious diseases.
An invasive hydatidiform mole (IHM) is a rare and aggressive complication of a gestational trophoblastic disease (GTD), which itself originates from the abnormal proliferation of trophoblastic cells, the tissue that normally develops into the placenta during pregnancy. IHMs are characterized by the invasion of molar villi into the myometrium (the muscular layer of the uterus) and can potentially spread to other organs through the bloodstream, leading to distant metastases.
IHMs usually arise from a complete hydatidiform mole (CHM), which is an abnormal conceptus with no embryonic or fetal development. CHMs are typically diploid and originate from the fertilization of an egg without genetic material (an empty egg or an egg with two sets of paternal chromosomes) by one or two sperm cells. This results in a conceptus with only paternal chromosomes, which leads to uncontrolled proliferation of trophoblastic tissue and the formation of grapelike vesicles filled with fluid (hydatidiform moles).
Invasive hydatidiform moles can cause various symptoms, such as vaginal bleeding, pelvic pain, or the presence of an enlarged uterus. They also pose a risk for developing choriocarcinoma, another type of gestational trophoblastic neoplasia (GTN), which is a malignant tumor that can metastasize and spread to other organs. Proper diagnosis and timely treatment are crucial to prevent severe complications and improve the prognosis for patients with IHMs. Treatment usually involves surgical removal of the mole, followed by chemotherapy to eliminate any residual disease and reduce the risk of GTN development.
Species specificity is a term used in the field of biology, including medicine, to refer to the characteristic of a biological entity (such as a virus, bacterium, or other microorganism) that allows it to interact exclusively or preferentially with a particular species. This means that the biological entity has a strong affinity for, or is only able to infect, a specific host species.
For example, HIV is specifically adapted to infect human cells and does not typically infect other animal species. Similarly, some bacterial toxins are species-specific and can only affect certain types of animals or humans. This concept is important in understanding the transmission dynamics and host range of various pathogens, as well as in developing targeted therapies and vaccines.
I'm sorry for any confusion, but "Israel" is not a medical term. It is a country located in the Middle East. If you have any medical questions or terms you would like defined, I would be happy to help!
Mole-rat
Ghana mole-rat
Micklem's mole-rat
Silvery mole-rat
Matabeleland mole-rat
Mashona mole-rat
Damaraland mole-rat
Kafue mole-rat
Ochre mole-rat
Mechow's mole-rat
Common mole-rat
Blind mole-rat
Ansell's mole-rat
Nigerian mole-rat
Cape mole-rat
Zambian mole-rat
Naked mole-rat
Bocage's mole-rat
Kenyan African mole-rat
Rudd's African mole-rat
Sandy blind mole-rat
East African mole-rat
Cape dune mole-rat
Embi African mole-rat
Storey's African mole-rat
King African mole-rat
Rwanda African mole-rat
Mianzini African mole-rat
Giant blind mole-rat
Greater blind mole-rat
Mole-rat - Wikipedia
Naked mole rats may help cure cancer | New Scientist
Digging into the genome of naked mole-rats | Lab Animal
Phostoxin for Mole, Rabbit & Rat Control | Rentokil
Naked Mole Rat - It's Nature
OBSERVATIONS ON ISRAELI POPULATIONS OF THE MOLE RAT SPALAX E. EHRENBERGI NEHRING 1898
Cartoonito's 'Naked Mole Rat Gets Dressed: The Underground Rock Experience' Voice Cast Revealed | Animation World Network
Rock Out With 'Naked Mole Rat Gets Dressed' at Seattle Children's Theatre | ParentMap
Darling's Mole-rat stock photo - Minden Pictures
Naked Mole Rat May Hold Secret To Long Life
Creature Feature: Naked Mole Rat | Assiniboine Park Conservancy
Cancer resistance insights gained from the blind mole rat - Oncology Nurse Advisor
Frontiers | Extended Postnatal Brain Development in the Longest-Lived Rodent: Prolonged Maintenance of Neotenous Traits in the...
U of R boffins discover wrinkle therapy chem may cure cancer in naked mole rats - DragonFlyEye.Net
Snugglies - 10.5' Naked Mole Rat - Fiesta Toy
Schumer, Gillibrand Announce Nearly $2 Million in Fed Health And Human Services Grant for University of Rochester & Naked Mole...
Researchers transfer longevity gene from naked mole rats to mice
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Courtesy of Mother Nature Series: The Blind mole-rat and magnetic navigation - Online Star Register
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Naked Mole Rats Longevity Protein Homeostasis FOXO Nrf2 Sulforaphane - Geres Dengle®
Rodent13
- Naked Mole Rat is a burrowing rodent inhabited to the parts of East Africa. (itsnature.org)
- The naked mole rat is a subterranean rodent native to East Africa. (nocamels.com)
- Genetic analysis comparing the mole rat with several other rodent species revealed that high levels NRG-1 in adults correlated with a longer life span. (nocamels.com)
- Her analysis revealed that the correlation between life span and NRG-1 levels was independent of evolutionary lineage - meaning that it was unique to the naked mole rat, not a common trait of these rodent species. (nocamels.com)
- The naked mole rat, a burrowing rodent that lives in colonies much like those of ants, has already proven to be an excellent tool for aging and biomedical research because it is resistant to cancer and maintains protein integrity in the brain despite being exposed to oxidative damage, Dr. Huchon says. (nocamels.com)
- They have isolated a specific chemical in the naked mole rat which seems to gird the rodent Lothario's cells against tumors. (dragonflyeye.net)
- The MUL genetic design used rodent stock primarily, ranging from the common sewer rat, through the naked mole rat, to the African mole rat. (wellisen.com)
- Metabolic clues to salubrious longevity in the brain of the longest-lived rodent: the naked mole-rat. (geresdengle.com)
- They are long lived, having a 30-year lifespan, considered a record for a rodent and 10 times longer than rats and mice. (animalsfyi.com)
- The greater mole-rat (Spalax microphthalmus) is a species of rodent in the family Spalacidae. (tinyblue.info)
- Bone remodeling in the longest living rodent, the naked mole-rat: Interelement variation and the effects of reproduction. (bvsalud.org)
- But while rat sightings decreased, the Centers for Disease Control and Prevention warned cities in lockdown to expect 'unusual or aggressive rodent behavior" as the furry critters hunted for food. (ny1.com)
- While the Health Department's Pest Control Services bureau - which inspects for rodents, conducts cleanings and runs the Rodent Indexing project that targets efforts in rat-heavy neighborhoods - managed to hold on to its $12.3 million budget, the Sanitation Department's rat reduction program took a hit. (ny1.com)
Rodents10
- Mole-rat (acche laal) or mole rat can refer to several groups of burrowing Old World rodents: Bathyergidae, a family of about 20 hystricognath species in six genera from Africa also called blesmols. (wikipedia.org)
- Rodents have an 85 percent genetic similarity to humans - so whatever is behind the naked mole rat's longevity may hold the key to longer and healthier lives for us as well. (nocamels.com)
- She studied seven species of rodents, including guinea pigs, mice, and mole rats, to determine the genetic relationships between them. (nocamels.com)
- Intriguingly, fully-grown naked mole-rats (NMRs) exhibit many traits typical of neonatal rodents. (frontiersin.org)
- Of all the underground rodents, the blind mole-rat went the farthest and most extreme in this discipline. (osr.org)
- For context, naked mole rats are mouse-sized rodents that live up to 41 years, nearly 10 times the lifespan of rodents of comparable size. (studyfinds.org)
- Naked mole rats are intriguing for researchers for a variety of reasons: they have the longest life span of rodents (average lifespan is 30 years), they are resistant to a variety of age-related diseases such as cancer, and they tend to remain fit and active until very advanced ages. (studyfinds.org)
- Naked Mole Rats (NMR), native to parts of East Africa , are extremely long lived rodents, living up to 8x's longer than comparably sized mice. (geresdengle.com)
- Even though naked mole rats are rodents (mammals) they have a social structure that resembles that of insects living in hives or colonies. (animalsfyi.com)
- Schewel, 35, and Sundrop are among a small number of rat hunters who regularly go out into the streets of New York to tackle the rodents in the piles of garbage where they thrive. (ny1.com)
Mice8
- To establish potential explanations for this tumor resistance, Miyawaki's team compared gene expression in mole-rat iPSCs to that of mole-rat fibroblasts and iPSCs derived from humans and mice. (nature.com)
- NewsNation ) - Researchers at the University of Rochester transferred a longevity gene from naked mole rats to mice, calling it a "groundbreaking endeavor. (wgnradio.com)
- It took us 10 years from the discovery of HMW-HA in the naked mole rat to showing that HMW-HA improves health in mice," said Vera Gorbunova, the Doris Johns Cherry professor of biology and medicine at Rochester. (wgnradio.com)
- In the wild, their lifespan is somewhat shorter, and in captivity there were specimens that lived over 20 years, which is even ten times longer than the lifespan of mice or rats of similar size. (osr.org)
- In this research, a gene from the mole rat was introduced into mice, leading to enhanced health and increased longevity in the mice. (studyfinds.org)
- These mole rats have almost 10 times more HMW-HA in their systems compared to mice and humans. (studyfinds.org)
- Remarkably, mice with the naked mole rat's gene variant showed heightened resistance to spontaneous tumors and chemically induced skin cancers. (studyfinds.org)
- Pocket mice steal from their bigger, faster cousins, the kangaroo rats, which are very good at bounding around on their hind legs and gathering seeds. (livescience.com)
Heterocephalus glaber5
- Heterocephalus glaber, the naked mole-rat. (wikipedia.org)
- A more famous and distant relative of this species present in Europe is the naked blind mole-rat (heterocephalus glaber), which inhabits a narrow area in eastern Africa. (osr.org)
- Mole rats are mutated Heterocephalus glaber, [1] or naked mole-rats, that are much larger than their pre-War counterparts. (wellisen.com)
- Naked mole rats (Heterocephalus glaber) are of great interest to scientists due to their unusually long life span and extreme cancer resistance. (georgetown.edu)
- The naked mole rat (NMR) ( Heterocephalus glaber) is increasingly considered an important biomedical research model for various conditions like hypoxic brain injury, cancer and nociception. (biomedcentral.com)
Mammals4
- Naked mole rats are one of the only eusocial mammals, meaning only one female in the colony (the queen) breeds and most other members spend their lives working for the colony! (assiniboinepark.ca)
- While all mammals possess this gene, the version found in the naked mole rat appears to promote more robust gene expression. (studyfinds.org)
- Mole rats are the only mammals that exhibit eusocial behavior. (animalsfyi.com)
- The pattern of bone remodeling of one of the most peculiar mammals in the world, the naked mole-rat (NMR), was assessed. (bvsalud.org)
Naked mole-rat c2
- It is our hope that combining arts and science will delight, educate, and inspire young people to learn more about our naked mole-rat colony," said Matt Cannella, Director of Advancement, Smithsonian's National Zoo and Conservation Biology Institute. (theadvfam.com)
- They were also fortunate to get a behind the scenes look at the naked mole rat colony at the Smithsonian National Zoological Park in Washington, DC, thanks to small mammal biologist David Kessler. (georgetown.edu)
Spalax3
- A Greater mole-rat (Spalax microphthalmus) usually gives birth to around 2 babies.With 1 litters per year, that sums up to a yearly offspring of 2 babies. (tinyblue.info)
- Adaptive loss of ultraviolet-sensitive/violet-sensitive (UVS/VS) cone opsin in the blind mole rat (Spalax ehrenbergi). (ox.ac.uk)
- In previous studies, fully functional rod and long-wavelength-sensitive (LWS) cone photopigments have been isolated from the eye of the subterranean blind mole rat (Spalax ehrenbergi superspecies). (ox.ac.uk)
20201
- The number of sightings increased to 1,658 in June 2020, and during the first five days of July, residents saw 220 rats, 20 fewer than the 240 reported during the same time span in 2019, city data show. (ny1.com)
Lifespan3
- It may not be much to look at, but the naked mole rat is impressive in its long and active lifespan. (nocamels.com)
- It stands out in comparison to the common rat, which lives an average of three years, in its 10 to 30 year lifespan. (nocamels.com)
- The naked mole rat, despite its less-than-appealing appearance, boasts a remarkable lifespan and a significant resistance to age-related diseases. (studyfinds.org)
20181
- A naked mole rat (NMR) is pictured at the University of Rochester January 31, 2018. (studyfinds.org)
Colony4
- Given the harshness of the environment in which both the naked mole rats and ants live in, it makes evolutionary sense to spread the reach of a colony for kilometers on end if need be, and if you come across another colony, it makes sense to snatch their pups and supplement your workforce. (bugbustersusa.com)
- The average colony size is about 80 mole rats. (animalsfyi.com)
- Soldier mole rats protect the colony from both predators, primarily snakes, and foreign mole rats, which they can smell from a distance. (animalsfyi.com)
- Celibate worker mole rats spend most of their time digging, as well as taking care of all the other work in the colony, such as tending to the nursery, finding tubers to eat, and watching over the den. (animalsfyi.com)
Wilbur4
- The story: Wilbur, a naked mole rat, decides that he wants to wear clothes, "just a simple business casual ensemble. (parentmap.com)
- They stage an intervention to convince Wilbur that naked mole rats should be… well, naked. (parentmap.com)
- This rock musical follows Wilbur J. Mole Rat Jr. and his fellow naked mole rats. (theadvfam.com)
- Suddenly, clothes fall from a hole in the ground above and Wilbur decides that clothes "make this mole whole. (theadvfam.com)
Species6
- Zokors (Myospalacinae), occasionally called mole-rats, about eight species from central and eastern Asia. (wikipedia.org)
- Of all the species the researchers studied, the naked mole rat had the most plentiful and long-lasting supply of the protein. (nocamels.com)
- Their eyes atrophied during evolution and are covered with skin, which is why the species got the name blind mole-rat. (osr.org)
- Naked mole rats are one of the weirdest mammalian species out there, even when you take out the fact that they are completely hairless. (bugbustersusa.com)
- Kidnapping is a behavior also witnessed in some primate species, but researchers believe that the mole rat behavior has a stronger link to the kidnapping seen in slave-making ant species such as Formica sanguinea. (bugbustersusa.com)
- Species-specific pat- and squamous metaplasia in rats and rhesus monkeys occur in terns of lesions in rats and monkeys suggest that regional dose specific regions of the nose with species-specific distribution pat- is a factor. (cdc.gov)
Adult2
- The researchers created induced pluripotent stem cells (iPSCs) by reprogramming skin fibroblast tissue from adult mole-rats in order to test its capacity for forming tumors, also called tumorigenicity. (nature.com)
- An adult blind mole-rat is 20-25 cm in size and can weigh from 100 to 500 grams. (osr.org)
Pests2
- Farmers sometimes see them as pests, but naked mole rats love farmers! (assiniboinepark.ca)
- Mole rats are common pests in the wasteland, but compared to many other enemies mole rats are generally weak. (wellisen.com)
Tunnel3
- Mole Rat and all his Fellow Mole Rats in the Tunnel have always been, well. (awn.com)
- Mole rats will tunnel underground to avoid their enemy or close in to attack unseen. (wellisen.com)
- The colonies, which can house up to 300 mole rats, have elaborate underground tunnel networks, nest chambers, and communal restrooms. (animalsfyi.com)
Moles5
- Phostoxin provides an effective alternative to traditional control methods for rabbits, moles and rats. (rentokil.co.uk)
- This product is only for the control of rabbits, rats and moles in their burrows. (rentokil.co.uk)
- A large number of mole hills gives the impression of many moles working in an area but often there is only one. (rentokil.co.uk)
- When you think of moles, the naked mole rat may spring to mind. (wellisen.com)
- Naked mole rats are neither moles nor rats, despite their names, and are not totally naked. (animalsfyi.com)
Cancer7
- THEY might be bald and ugly, but naked mole rats never get cancer. (newscientist.com)
- It's almost impossible to culture naked mole rat cells in the lab, which made Andrei Seluanov and Vera Gorbunova from Rochester University, New York, wonder if this might be linked to their ability to resist cancer. (newscientist.com)
- On its own, however, this study demonstrates the value of the naked mole-rat as a model for cancer resistance, with work already underway to demystify and translate its unique resilience into biomedical applications. (nature.com)
- Seluanov and Gorbunova then showed that when HMW-HA was removed, the cells became susceptible to tumors, confirming that the chemical did play a role in making naked mole rats cancer-proof. (dragonflyeye.net)
- The researchers previously learned that HMW-HA is also one mechanism responsible for the unusual resistance naked mole rats have to cancer. (wgnradio.com)
- Previously, the researchers identified HMW-HA as a key factor in the naked mole rats' exceptional cancer resistance. (studyfinds.org)
- This fall our students look forward to discussing recent evidence that naked mole rat cancer resistance may be due to unusually high levels of hyaluronate in their skin and other tissues (Tian et al. (georgetown.edu)
Researchers3
- The researchers, from Tel Aviv University's Department of Zoology, the University of Texas Health Science Center and the City College of New York are working together to determine whether the naked mole rat's unusually high levels of NRG-1, a neuroprotecting protein, is behind the naked mole rat's three-decade life span. (nocamels.com)
- The researchers engineered a mouse model to produce the naked mole rat's version of the hyaluronan synthase 2 gene , responsible for creating the protein that yields HMW-HA. (studyfinds.org)
- A year later, the researchers found two pups in one of the original 26 invading colonies that had the characteristics of mole rats from one of the colonies that had been invaded and exterminated. (bugbustersusa.com)
Humans1
- Not only this, but compared to humans, the naked mole rat's body shows little decline due to aging. (nocamels.com)
Resistance1
- According to the University of Rochester , naked mole rats have long captured the attention of scientists for their lengthy lifespans and resistance to age-related diseases. (wgnradio.com)
Blind5
- Let's learn more about the amazing blind mole-rat! (osr.org)
- As a replica of the blind mole-rat's place of residence, a labyrinth was created, which has a central space in the middle, from which eight tunnels lead, and at the end of each there is a room. (osr.org)
- The blind mole-rats are divided into three groups. (osr.org)
- Are Naked Mole Rats Blind? (animalsfyi.com)
- Naked mole rats are not entirely blind, but they have very limited vision. (animalsfyi.com)
Willems5
- Naked Mole Rat Gets Dressed: The Underground Rock Experience is part of WarnerMedia's multi-year deal with Willems and producing partner Stampede Ventures to create live-action Storytime Specials and multiple animated and live-action series based on the author's popular children's books. (awn.com)
- Caldecott winner and beloved author Mo Willems adapted his book, "Naked Mole Rat Gets Dressed," for the stage, writing the script and lyrics. (parentmap.com)
- Naked Mole Rat" is making its world premiere at Seattle Children's Theatre , and Willems attended the show's opening night, March 23. (parentmap.com)
- Naked Mole Rat is one of Willems' standalone book characters, and the show is packed with his signature wit. (parentmap.com)
- Mo Willems' best-selling 2009 picture book Naked Mole Rat Gets Dressed inspired this show. (theadvfam.com)
Grande1
- The other mole rats - Tall, Venti and Grande - are appalled. (parentmap.com)
Ugly2
- Mole rats are a pretty ugly, obscure bunch of creatures. (corante.com)
- Naked mole rats are not particularly attractive with their buckteeth and lack of hair (some would say they're downright ugly). (animalsfyi.com)
Burrows3
- Rats that infest farm buildings, poultry sheds and pig houses can often be found living in nearby burrows. (rentokil.co.uk)
- Bankings, hedgerows and overgrown vegetation all provide ideal sites for rats to create burrows, from which they can spread to the surrounding buildings. (rentokil.co.uk)
- In the early 90s, biologists conducted a study in Kenya, where they found that 26 naked mole rat colonies expanded their burrows into neighboring territories. (bugbustersusa.com)
Colonies4
- Naked mole rats are fairly small in size (about 4 inches) but they have giant colonies composed of as many as 300 workers. (bugbustersusa.com)
- Why do Naked Mole Rats Live in Colonies? (animalsfyi.com)
- Therefore, naked mole rats have evolved to live in colonies with a large workforce that vastly improves the odds of survival for each individual. (animalsfyi.com)
- To survive the close confines of their colonies, naked mole rats have evolved a rigid social structure that is like that of insects (eusocial). (animalsfyi.com)
20211
- Budget documents show the Sanitation Department will move $1.5 million away from its Rat Mitigation Project in 2021 and up the amount to $1.7 million in 2024, which will mean 25 percent less trash pick-ups in areas with big rat populations. (ny1.com)
Wear clothes1
- Do Naked Mole Rats Wear Clothes? (theadvfam.com)
Litter2
- In the wild, naked mole rats are mostly known to breed once in a year, if the litter survives. (itsnature.org)
- How many baby Greater mole-rats are in a litter? (tinyblue.info)
Animals4
- It is important to recognise that the mole is a solitary animal and its workings are usually distinct from those of neighbouring animals. (rentokil.co.uk)
- Surprisingly, the naked mole rat gene was different from HAS2 in all other animals. (dragonflyeye.net)
- In addition naked mole rats were very slow at recycling HMW-HA, which contributed to the accumulation of the chemical in the animals' tissues. (dragonflyeye.net)
- The animals were seperated into four groups five rats each. (unair.ac.id)
Fallout10
- Here's what we know about where the mole rat brood mother can spawn in Fallout 76. (wellisen.com)
- CreatureAnimal Use this guide page for "Mole Rat" to get details on level, faction, perks, aggression, possible loot drops and location spawn areas on Fallout 76. (wellisen.com)
- Fallout 76 Mole Rat Brood Mother Spawn With Fallout 76 Mole Miner locations covered, check out our guides on Mole Rat Brood Mother and Bubblegum locations. (wellisen.com)
- Main article: Mole rats (Fallout 76) Mole rats tend to travel in dens of 3-5 and attack by lunging with their chisel-like teeth. (wellisen.com)
- If you do decide to look for Fallout 76 Mole Miner locations, it's best to equip yourself with weapons and enough ammo. (wellisen.com)
- Collect a blood sample from a Mole Rat is an objective in Fallout 76 (F76). (wellisen.com)
- Fallout 76 (XB1) Plan: Molerat Wind Chime. (wellisen.com)
- More Fallout 76 Mole Miner locations can be found in Appalachia's Savage Divide region. (wellisen.com)
- Listed here is npc information for Mole Rat from fallout 76. (wellisen.com)
- Fallout 76 Mole Rat is an Enemy in the game. (wellisen.com)
Teeth2
- Mole rats have lips that close behind their teeth to keep the dirt out of their mouths when they're digging. (animalsfyi.com)
- The pair work as a team, with Schewel flushing rats out of the trash and Sundrop grabbing them in his teeth, shaking their bodies and breaking their backs, Schewel says. (ny1.com)
Decides1
- Through a series of witty, silly, tuneful rock songs, the leader of the naked mole rats ultimately decides that each mole rat can choose whether to dress or remain naked. (theadvfam.com)
Testes2
- Hence, this research to assess the effect of Moringa oleifera leaf extract (MOLE) on the male rat by assessing changes in testes induced by high temperature. (unair.ac.id)
- MOLE could prevent the damage caused to the testes induces high temperature. (unair.ac.id)
Content1
- They will be providing engaging content about naked mole rats in the theatre lobby for children to explore before or after the performance. (theadvfam.com)
Creatures1
- Mole rats are creatures found in Appalachia. (wellisen.com)
Tumor1
- They identified that a tumor-suppressor gene, ARF , is highly expressed in mole-rat iPSCs but suppressed in human- and mouse-derived iPSCs. (nature.com)
Brain1
- Age-related changes in the proteostasis network in the brain of the nakedmole-rat. (geresdengle.com)
Rochester2
- The Rochester team also identified the gene, named HAS2, responsible for making HMW-HA in the naked mole rat. (dragonflyeye.net)
- ROCHESTER, N.Y. - The naked mole rat is bringing modern medicine one step closer to creating the "elixir of life. (studyfinds.org)
Tissue1
- Site-specificity of and cell proliferation would allow DPX and cell proliferation formaldehyde-induced lesions in rats and monkeys implicates data to be interpolated from measurement sites to the rest of the regional tissue susceptibility and dose as factors potentially nasal passage. (cdc.gov)
Tail1
- He walked on stage wearing bright red glasses, bright red shoes and a long mole rat tail poking out his backside. (parentmap.com)
Live1
- Studies in Kenya have shown that naked mole rats live in extremely hard soils - so hard that you can hardly dig it up with a pick. (animalsfyi.com)
Size1
- While gassing is unlikely to provide the complete solution to any rat infestation , it can be a valuable method of reducing the size of a rat population quickly, following which rodenticide baits can be used more effectively to control the remaining population. (rentokil.co.uk)
Pants1
- The additional voice cast includes Ron Funches as Les Pants the Weather Mole, Thomas Lennon as Stark Naked the News Mole, and Jenna Ushkowitz as the Secret Service Mole. (awn.com)
Long2
- Rat sightings have been steadily increasing since New York City began reopening after its months-long stay-in-place, when complaints to 311 reached record lows. (ny1.com)
- The amateur rat hunter, whose efforts barely make a dent, doesn't think his hobby is a long-term solution to New York City's rat problem, but he's got an equally novel pitch for lawmakers: repeal a ban on ferrets enacted by former Mayor Rudy Giuliani. (ny1.com)
Monkey3
- Anatomically accurate, 3-dimensional computational fluid dy- on major airflow patterns, air-phase diffusion, and absorption namics models of F344 rat, rhesus monkey, and human nasal at the air-lining interface. (cdc.gov)
- h-ppm) in the rat, monkey, and human respectively. (cdc.gov)
- Comparative metabolism study of ß-lapachone in mouse, rat, dog, monkey, and human liver microsomes using liquid chromatography-tandem mass spectrometry. (medlineplus.gov)
Family1
- WarnerMedia Kids & Family and Stampede Ventures have unveiled the cast of their upcoming Naked Mole Rat Gets Dressed: The Underground Rock Experience . (awn.com)
High1
- Schewel and Sundrop go out about four nights a week into neighborhoods with high rat populations - such as Bedford-Stuyvesant and Bushwick - to kill as many rats as Sundrop can catch, sometimes up to 20 in just four hours, Schewel says. (ny1.com)
Underground1
- Naked mole rats spend their entire lives underground. (animalsfyi.com)
Hunt1
- But Schewel says that New Yorkers are already getting active, asking him to come to their neighborhoods to hunt or even requesting rat-killing trainings for their own pet dogs. (ny1.com)
Human1
- Additionally, mole-rat iPSCs have a disrupted ERAS gene, which is expressed in human- and mouse-derived iPSCs and is associated with tumorigenesis. (nature.com)
Society1
- Carol Kane as Grand-Mah, the larger-than-life matriarch of the Mole Rat society. (awn.com)