The three membranes that cover the BRAIN and the SPINAL CORD. They are the dura mater, the arachnoid, and the pia mater.
A delicate membrane enveloping the brain and spinal cord. It lies between the PIA MATER and the DURA MATER. It is separated from the pia mater by the subarachnoid cavity which is filled with CEREBROSPINAL FLUID.
Inflammation of the coverings of the brain and/or spinal cord, which consist of the PIA MATER; ARACHNOID; and DURA MATER. Infections (viral, bacterial, and fungal) are the most common causes of this condition, but subarachnoid hemorrhage (HEMORRHAGES, SUBARACHNOID), chemical irritation (chemical MENINGITIS), granulomatous conditions, neoplastic conditions (CARCINOMATOUS MENINGITIS), and other inflammatory conditions may produce this syndrome. (From Joynt, Clinical Neurology, 1994, Ch24, p6)
Benign and malignant neoplastic processes that arise from or secondarily involve the meningeal coverings of the brain and spinal cord.
The outermost of the three MENINGES, a fibrous membrane of connective tissue that covers the brain and the spinal cord.
A superfamily of nematodes of the order STRONGYLIDA. Characteristics include a fluid-filled outer layer of cuticle and a reduced mouth and bursa.
A villous structure of tangled masses of BLOOD VESSELS contained within the third, lateral, and fourth ventricles of the BRAIN. It regulates part of the production and composition of CEREBROSPINAL FLUID.
A species of the genus MACACA which inhabits Malaya, Sumatra, and Borneo. It is one of the most arboreal species of Macaca. The tail is short and untwisted.
A genus of parasitic nematodes of the superfamily METASTRONGYLOIDEA. Two species, ANGIOSTRONGYLUS CANTONENSIS and A. vasorum, infest the lungs of rats and dogs, respectively. A. cantonensis is transmissible to man where it causes frequently fatal infection of the central nervous system.
Irrigation of the nose with saline or irrigation solutions for diagnostic or therapeutic purposes. It is used to remove irritants, allergens, or microorganisms from the nose.
Neoplasms composed of fibrous tissue, the ordinary connective tissue of the body, made up largely of yellow or white fibers. The concept does not refer to neoplasms located in fibrous tissue.
A relatively common neoplasm of the CENTRAL NERVOUS SYSTEM that arises from arachnoidal cells. The majority are well differentiated vascular tumors which grow slowly and have a low potential to be invasive, although malignant subtypes occur. Meningiomas have a predilection to arise from the parasagittal region, cerebral convexity, sphenoidal ridge, olfactory groove, and SPINAL CANAL. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2056-7)
An inflammatory process involving the brain (ENCEPHALITIS) and meninges (MENINGITIS), most often produced by pathogenic organisms which invade the central nervous system, and occasionally by toxins, autoimmune disorders, and other conditions.
Primary or secondary neoplasm in the ARACHNOID or SUBARACHNOID SPACE. It appears as a diffuse fibrotic thickening of the MENINGES associated with variable degrees of inflammation.
A watery fluid that is continuously produced in the CHOROID PLEXUS and circulates around the surface of the BRAIN; SPINAL CORD; and in the CEREBRAL VENTRICLES.

Ultramicroscopic structures of the leptomeninx of mice with communicating hydrocephalus induced by human recombinant transforming growth factor-beta 1. (1/402)

An experimental model of communicating hydrocephalus was developed based on intrathecal injection of human recombinant transforming growth factor-beta 1 (hrTGF-beta 1) in the mouse. To clarify the mechanism of this hydrocephalus model, the ultrastructure of the leptomeninx in the process of ventricular dilation was examined in C57/BL6 mice injected intrathecally with 60 ng of hrTGF-beta 1. The leptomeninx was examined at various periods after injection by light and electron microscopy. Immunostaining for fibroblasts and macrophages was also performed. Leptomeninx within a week after injection showed that the thin cytoplasmic processes of leptomeningeal cells formed a laminated structure with a meshwork, which was almost the same as the controls. In the second week, many cells with a round nucleus appeared in the leptomeninx. Immunohistochemically, these cells were positive for anti-fibroblast antibody and negative for anti-Mac-1 and anti-macrophage BM-8 antibodies. Three weeks later, the laminated structure was disrupted and abundant deposition of collagen fibers was found in the inter-cellular space of the leptomeninx. Such inter-meningeal fibrosis would disturb cerebrospinal fluid flow in the mouse leptomeninx and cause slowly progressive ventricular dilation.  (+info)

Transthyretin Leu12Pro is associated with systemic, neuropathic and leptomeningeal amyloidosis. (2/402)

We report a middle-aged woman with a novel transthyretin (TTR) variant, Leu12Pro. She had extensive amyloid deposition in the leptomeninges and liver as well as the involvement of the heart and peripheral nervous system which characterizes familial amyloid polyneuropathy caused by variant TTR. Clinical features attributed to her leptomeningeal amyloid included radiculopathy, central hypoventilation, recurrent subarachnoid haemorrhage, depression, seizures and periods of decreased consciousness. MRI showed a marked enhancement throughout her meninges and ependyma, and TTR amyloid deposition was confirmed by meningeal biopsy. The simultaneous presence of extensive visceral amyloid and clinically significant deposits affecting both the peripheral and central nervous system extends the spectrum of amyloid-related disease associated with TTR mutations. The unusual association of severe peripheral neuropathy with symptoms of leptomeningeal amyloid indicates that leptomeningeal amyloidosis should be considered part of the syndrome of TTR-related familial amyloid polyneuropathy.  (+info)

Meningioangiomatosis. A comprehensive analysis of clinical and laboratory features. (3/402)

Meningioangiomatosis (MA) is a rare, benign, focal lesion of the leptomeninges and underlying cerebral cortex characterized by leptomeningeal and meningovascular proliferation. It may occur sporadically or in association with neurofibromatosis type 2. Previous reports have emphasized histological and imaging features. Data on the management of these patients are sparse, and electrophysiological features of MA lesions have not been published. We assessed the clinical, electrophysiological, histopathological and imaging features as well as the surgical outcome in MA, and compared MA with and without neurofibromatosis. Seven patients with MA at our centre were investigated and their outcome was assessed. A review of the literature is included. MA exhibits a wide range of clinical, imaging, histopathological and electrophysiological features, making the diagnosis difficult. Sporadic MA cases are not associated with neurofibromatosis and the two disorders are genetically distinct. Medically refractory, localization-related epilepsy is the commonest presentation in sporadic cases, but atypical presentations also occur. Unlike sporadic cases, MA with neurofibromatosis is often found incidentally, does not produce seizures, occurs less frequently (ratio of 1:4), and is multifocal. MRI findings in MA correspond to the histological picture. However, the appearance on imaging is non-specific and may suggest cystic atrophy, angioma and tumours. Several abnormalities have been found in close proximity to MA lesions, i.e. meningioma, oligodendroglioma, arteriovenous malformation, encephalocoel and orbital erosion. In spite of histopathological diversity, MA lesions are either predominantly cellular or vascular. Immunohistochemical results are inconsistent among cases, add little to the diagnosis, and do not support a meningeal origin. Electrocorticographic recordings from the surface and within MA lesions revealed a spectrum of electrophysiological expressions. Intrinsic epileptogenicity of MA lesions was documented in some cases. Epileptogenicity was confined to the perilesional cortex in some patients and it was complex (extralesional, multifocal, generalized) in others. Only 43% of our patients became seizure-free postoperatively compared with 68% previously reported, and >70% of our patients and those in the literature continued to require antiepileptic drugs. This is in keeping with the diverse electrophysiology of MA and suggests a less optimistic postoperative outcome than previously recognized.  (+info)

Tumor necrosis factor alpha is a determinant of pathogenesis and disease progression in mycobacterial infection in the central nervous system. (4/402)

The pathogenesis of tuberculous meningitis, a devastating complication of tuberculosis in man, is poorly understood. We previously reported that rabbits with experimental tuberculous meningitis were protected from death by a combination of antibiotics and thalidomide therapy. Survival was associated with inhibition of tumor necrosis factor alpha (TNF-alpha) production by thalidomide. To test whether cerebrospinal fluid (CSF) levels of TNF-alpha correlated with pathogenesis, the response of rabbits infected in the central nervous system (CNS) with various mycobacterial strains was studied. CNS infection with Mycobacterium bovis Ravenel, M. bovis bacillus Calmette-Guerin (BCG) Pasteur, and M. bovis BCG Montreal were compared. M. bovis Ravenel induced the highest levels of TNF-alpha in the CSF in association with high leukocytosis, protein accumulation, and severe meningeal inflammation. BCG Pasteur had intermediate effects, and BCG Montreal was the least virulent. In addition, M. bovis Ravenel numbers were highest in the brain and CSF and the bacilli also disseminated more efficiently to distant organs, compared with BCG Pasteur and BCG Montreal. In subsequent experiments, rabbits were infected with either recombinant M. bovis BCG Montreal (vector), or BCG Montreal expressing the murine gene for TNF-alpha (BCG mTNF-alpha). BCG Montreal was rendered virulent by the expression of murine TNF-alpha, as demonstrated by high CSF leukocytosis, high protein accumulation, severe meningeal inflammation, persistent bacillary load, and progressive clinical deterioration. Taken together, these results demonstrate that the level of TNF-alpha produced during mycobacterial CNS infection determines, at least in part, the extent of pathogenesis.  (+info)

MR of CNS sarcoidosis: correlation of imaging features to clinical symptoms and response to treatment. (5/402)

BACKGROUND AND PURPOSE: Sarcoidosis is an idiopathic systemic granulomatous disease, recognized in a patient when clinical and radiologic findings are confirmed by histopathologic analysis. The objective was to identify a relationship between MR imaging and clinical findings in CNS sarcoidosis. METHODS: The clinical charts of 461 patients with biopsy-proved sarcoidosis were reviewed retrospectively. Criteria for including patients in the study included those with symptoms referable to the CNS, excluding those with another explanation for their symptoms, those with headaches or other subjective complaints without accompanying objective findings, and those with peripheral neuropathy other than cranial nerve involvement or myopathy without CNS manifestations. Thirty-four of 38 patients whose conditions met the criteria for CNS sarcoidosis underwent a total of 82 MR examinations. The positive imaging findings were divided into categories as follows: pachymeningeal, leptomeningeal, nonenhancing brain parenchymal, enhancing brain parenchymal, cranial nerve, and spinal cord and nerve root involvement. Treatment response, clinical symptomatology, and any available histopathologic studies were analyzed with respect to imaging manifestations in each of the categories. RESULTS: Eighty-two percent of the patients with sarcoidosis with neurologic symptoms referable to the CNS had findings revealed by MR imaging. However, eight (40%) of 20 cranial nerve deficits seen at clinical examination of 13 patients were not seen at contrast-enhanced MR imaging, and 50% of the patients with symptoms referable to the pituitary axis had no abnormal findings on routine contrast-enhanced MR images. In contradistinction, 44% of 18 cranial nerves in nine patients with MR evidence of involvement had no symptoms referable to the involved cranial nerve. Clinical and radiologic deterioration occurred more commonly with leptomeningeal and enhancing brain parenchymal lesions. CONCLUSION: MR imaging can be used to confirm clinical suspicion and to show subclinical disease and the response of pathologic lesions to treatment.  (+info)

Multifocal meningioangiomatosis: a report of two cases. (6/402)

We report the CT and MR findings in two patients with multifocal meningioangiomatosis, neither of whom had a family history or stigmata of neurofibromatosis. All lesions were located in the cortical and subcortical areas and had round dense calcifications with eccentric cysts. The masses were associated with surrounding edema and gliosis.  (+info)

Magnetization transfer MR imaging in CNS tuberculosis. (7/402)

BACKGROUND AND PURPOSE: CNS tuberculosis may simulate other granulomas and meningitis on MR images. The purpose of this study was to improve the characterization of lesions in CNS tuberculosis and to assess the disease load using magnetization transfer (MT) imaging. METHODS: A total of 107 tuberculomas in seven patients with or without meningitis and 15 patients with tuberculosis meningitis alone were studied. Fifteen patients with cysticercus granulomas with T2 hypointensity, five patients each with viral and pyogenic meningitis, and two patients with cryptococcal meningitis were also studied. The MT ratios were calculated from tuberculomas, cysticercus granulomas, and thickened meninges in tuberculous, viral, pyogenic, and cryptococcal meningitis and were compared within each pathologic group and with the MT ratio of different regions of normal brain parenchyma. Detectability of lesions on T1-weighted MT spin-echo (SE) images was compared with that on conventional SE and postcontrast MT-SE images. RESULTS: Thickened meninges appeared hyperintense relative to surrounding brain parenchyma in the basal and supratentorial cisterns on precontrast MT-SE images in all 18 patients with tuberculosis meningitis. These meninges were not seen or were barely visible on conventional SE images, and enhanced on postcontrast MT-SE images. The MT ratio from the thickened meninges of tuberculous meningitis was significantly lower than that from the meninges in cryptococcal and pyogenic disease and significantly higher than the meninges in viral meningoencephalitis. The MT ratio from T2 visible and invisible tuberculomas appeared to be significantly lower than that of normal white matter. The MT ratio of T2 hypointense cysticercus granuloma was significantly higher than that of T2 hypointense tuberculoma. CONCLUSION: Precontrast MT-SE imaging helps to better assess the disease load in CNS tuberculosis by improving the detectability of the lesions. With the use of MT ratios, it may be possible to differentiate tuberculosis from similar-appearing infective lesions on MR images.  (+info)

Sclerosing spinal pachymeningitis. A complication of intrathecal administration of Depo-Medrol for multiple sclerosis. (8/402)

Reported complications of intrathecal steroid therapy include aseptic meningitis, infectious meningitis, and arachnoiditis. We report a case of sclerosing spinal pachymeningitis complicating the attempted intrathecal administration of Depo-Medrol for multiple sclerosis. The lesion is characterised by concentric laminar proliferation of neomembranes within the subdural space of the entire spinal cord and cauda equina, resulting from repeated episodes of injury and repair to the spinal dura mater by Depo-Medrol. There is clinical and laboratory evidence that Depo-Medrol produces meningeal irritation and that the vehicle is the necrotising fraction.  (+info)

The meninges are the protective membranes that cover the brain and spinal cord. They consist of three layers: the dura mater (the outermost, toughest layer), the arachnoid mater (middle layer), and the pia mater (the innermost, delicate layer). These membranes provide protection and support to the central nervous system, and contain blood vessels that supply nutrients and remove waste products. Inflammation or infection of the meninges is called meningitis, which can be a serious medical condition requiring prompt treatment.

The arachnoid is one of the three membranes that cover the brain and the spinal cord, known as the meninges. It is located between the dura mater (the outermost layer) and the pia mater (the innermost layer). The arachnoid is a thin, delicate membrane that is filled with cerebrospinal fluid, which provides protection and nutrition to the central nervous system.

The arachnoid has a spider-web like appearance, hence its name, and it is composed of several layers of collagen fibers and elastic tissue. It is highly vascularized, meaning that it contains many blood vessels, and it plays an important role in regulating the flow of cerebrospinal fluid around the brain and spinal cord.

In some cases, the arachnoid can become inflamed or irritated, leading to a condition called arachnoiditis. This can cause a range of symptoms, including pain, muscle weakness, and sensory changes, and it may require medical treatment to manage.

Meningitis is a medical condition characterized by the inflammation of the meninges, which are the membranes that cover the brain and spinal cord. This inflammation can be caused by various infectious agents, such as bacteria, viruses, fungi, or parasites, or by non-infectious causes like autoimmune diseases, cancer, or certain medications.

The symptoms of meningitis may include fever, headache, stiff neck, nausea, vomiting, confusion, and sensitivity to light. In severe cases, it can lead to seizures, coma, or even death if not treated promptly and effectively. Bacterial meningitis is usually more severe and requires immediate medical attention, while viral meningitis is often less severe and may resolve on its own without specific treatment.

It's important to note that meningitis can be a serious and life-threatening condition, so if you suspect that you or someone else has symptoms of meningitis, you should seek medical attention immediately.

Meningeal neoplasms, also known as malignant meningitis or leptomeningeal carcinomatosis, refer to cancerous tumors that originate in the meninges, which are the membranes covering the brain and spinal cord. These tumors can arise primarily from the meningeal cells themselves, although they more commonly result from the spread (metastasis) of cancer cells from other parts of the body, such as breast, lung, or melanoma.

Meningeal neoplasms can cause a variety of symptoms, including headaches, nausea and vomiting, mental status changes, seizures, and focal neurological deficits. Diagnosis typically involves imaging studies (such as MRI) and analysis of cerebrospinal fluid obtained through a spinal tap. Treatment options may include radiation therapy, chemotherapy, or surgery, depending on the type and extent of the tumor. The prognosis for patients with meningeal neoplasms is generally poor, with a median survival time of several months to a year.

Dura Mater is the thickest and outermost of the three membranes (meninges) that cover the brain and spinal cord. It provides protection and support to these delicate structures. The other two layers are called the Arachnoid Mater and the Pia Mater, which are thinner and more delicate than the Dura Mater. Together, these three layers form a protective barrier around the central nervous system.

Metastrongyloidea is a superfamily of nematode (roundworm) parasites that have complex life cycles involving intermediate hosts such as mollusks or arthropods. The adult worms typically reside in the respiratory system, lungs, or other tissues of various mammalian hosts, including humans.

The Metastrongyloidea superfamily includes several medically and veterinarily important genera such as:

* Metastrongylus (e.g., M. pudendotectus, M. salmi) - found in the lungs of suids (pigs, wild boars, warthogs)
* Angiostrongylus (e.g., A. cantonensis, A. costaricensis) - parasites of rodents and other mammals, with zoonotic potential
* Crenosoma (e.g., C. vulpis, C. striatum) - found in the respiratory tracts of canids (dogs, wolves, foxes) and mustelids (otters, weasels)
* Varestrongylus (e.g., V. capreoli, V. alces) - parasites of cervids (deer, elk, moose)

These nematodes are often associated with respiratory and pulmonary diseases in their respective hosts, causing conditions such as pneumonia, bronchitis, or granulomatous inflammation. In humans, angiostrongyliasis can lead to eosinophilic meningitis, a severe neurological condition caused by the migration of larvae through the central nervous system.

The choroid plexus is a network of blood vessels and tissue located within each ventricle (fluid-filled space) of the brain. It plays a crucial role in the production of cerebrospinal fluid (CSF), which provides protection and nourishment to the brain and spinal cord.

The choroid plexus consists of modified ependymal cells, called plexus epithelial cells, that line the ventricular walls. These cells have finger-like projections called villi, which increase their surface area for efficient CSF production. The blood vessels within the choroid plexus transport nutrients, ions, and water to these epithelial cells, where they are actively secreted into the ventricles to form CSF.

In addition to its role in CSF production, the choroid plexus also acts as a barrier between the blood and the central nervous system (CNS), regulating the exchange of substances between them. This barrier function is primarily attributed to tight junctions present between the epithelial cells, which limit the paracellular movement of molecules.

Abnormalities in the choroid plexus can lead to various neurological conditions, such as hydrocephalus (excessive accumulation of CSF) or certain types of brain tumors.

"Macaca nemestrina," also known as the pig-tailed macaque, is not a medical term but a species name in biology. It refers to a specific species of monkey that is native to Southeast Asia. The pig-tailed macaque is a medium-sized monkey with a reddish-brown fur and a distinctive tail that resembles a pig's tail. They are omnivorous and live in social groups that can range from a few individuals to several hundred.

While "Macaca nemestrina" may not have a direct medical definition, these monkeys have been used as models in biomedical research due to their close genetic relationship with humans. Some studies involving pig-tailed macaques have contributed to our understanding of various human diseases and conditions, such as infectious diseases, neurological disorders, and reproductive health. However, it is important to note that the use of animals in research remains a controversial topic, and ethical considerations must be taken into account when conducting such studies.

Angiostrongylus is a genus of parasitic nematode roundworms that are known to cause serious diseases in humans and animals. The most common species that affects humans is Angiostrongylus cantonensis, also known as the rat lungworm. This parasite primarily infects rats but can accidentally infect humans through the consumption of raw or undercooked intermediate hosts, such as snails, slugs, or freshwater shrimp.

Infection with Angiostrongylus cantonensis can lead to a condition called angiostrongyliasis, which primarily affects the central nervous system. Symptoms of this disease may include severe headaches, neck stiffness, nausea, vomiting, and in some cases, temporary paralysis or long-term neurological damage.

Preventing Angiostrongylus infection involves avoiding the consumption of raw or undercooked intermediate hosts and practicing good hygiene when handling raw produce. In areas where the parasite is endemic, public health education campaigns are often implemented to raise awareness about the risks associated with this infection and promote preventative measures.

Nasal lavage, also known as nasal washing or saline irrigation, is a procedure in which a saline solution is used to flush out the nasal passages. This is often done to help relieve symptoms associated with nasal congestion, allergies, sinusitis, and other respiratory conditions. The process involves instilling the saline solution into one nostril and allowing it to flow out through the other, taking with it any mucus, debris, or irritants that may be present in the nasal passages. This can help promote better breathing, reduce inflammation, and alleviate symptoms such as sinus pressure, headaches, and sneezing. Nasal lavage can be performed using a variety of devices, including bulb syringes, neti pots, or specialized squeeze bottles designed specifically for this purpose.

Neoplasms of fibrous tissue are abnormal growths or tumors that originate from fibroblasts, the cells responsible for producing connective tissue in the body. These neoplasms can be benign or malignant (cancerous). Benign fibrous neoplasms include fibromas and fibrohistiocytic tumors, while malignant fibrous neoplasms are called fibrosarcomas. Fibrosarcomas are aggressive tumors that invade surrounding tissues and can metastasize (spread) to other parts of the body.

Fibrous tissue neoplasms can occur in any part of the body, but they are most commonly found in the soft tissues such as muscles, tendons, and ligaments. They can also develop in bones, where they are called osteosarcomas. Symptoms of fibrous tissue neoplasms depend on their size and location, but may include a painless mass or swelling, limited mobility, or pain if the tumor is pressing on nerves or blood vessels.

Diagnosis of fibrous tissue neoplasms typically involves imaging tests such as X-rays, CT scans, or MRI scans, followed by a biopsy to confirm the type and grade of the tumor. Treatment options may include surgery, radiation therapy, chemotherapy, or a combination of these approaches. Regular follow-up care is important to monitor for recurrence or metastasis.

A meningioma is a type of slow-growing tumor that forms on the membranes (meninges) surrounding the brain and spinal cord. It's usually benign, meaning it doesn't spread to other parts of the body, but it can still cause serious problems if it grows and presses on nearby tissues.

Meningiomas most commonly occur in adults, and are more common in women than men. They can cause various symptoms depending on their location and size, including headaches, seizures, vision or hearing problems, memory loss, and changes in personality or behavior. In some cases, they may not cause any symptoms at all and are discovered only during imaging tests for other conditions.

Treatment options for meningiomas include monitoring with regular imaging scans, surgery to remove the tumor, and radiation therapy to shrink or kill the tumor cells. The best treatment approach depends on factors such as the size and location of the tumor, the patient's age and overall health, and their personal preferences.

Meningoencephalitis is a medical term that refers to an inflammation of both the brain (encephalitis) and the membranes covering the brain and spinal cord (meninges), known as the meninges. It is often caused by an infection, such as bacterial or viral infections, that spreads to the meninges and brain. In some cases, it can also be caused by other factors like autoimmune disorders or certain medications.

The symptoms of meningoencephalitis may include fever, headache, stiff neck, confusion, seizures, and changes in mental status. If left untreated, this condition can lead to serious complications, such as brain damage, hearing loss, learning disabilities, or even death. Treatment typically involves antibiotics for bacterial infections or antiviral medications for viral infections, along with supportive care to manage symptoms and prevent complications.

Meningeal carcinomatosis, also known as leptomeningeal metastasis or neoplastic meningitis, is a medical condition characterized by the spread of cancer cells to the meninges, which are the thin layers of tissue that cover and protect the brain and spinal cord.

In this condition, cancer cells from a primary tumor or metastatic cancer elsewhere in the body invade the cerebrospinal fluid (CSF) and spread throughout the meningeal spaces, causing inflammation and damage to the surrounding tissues. This can result in various neurological symptoms such as headache, nausea, vomiting, seizures, confusion, weakness, or paralysis, depending on the location of the cancer cells in the meninges.

Meningeal carcinomatosis is a serious and often life-threatening complication of advanced cancer, with a poor prognosis and limited treatment options. It can occur in various types of cancer, including lung, breast, melanoma, and hematological malignancies such as leukemia and lymphoma. Early diagnosis and prompt treatment are crucial to improve the quality of life and prolong survival in affected patients.

Cerebrospinal fluid (CSF) is a clear, colorless fluid that surrounds and protects the brain and spinal cord. It acts as a shock absorber for the central nervous system and provides nutrients to the brain while removing waste products. CSF is produced by specialized cells called ependymal cells in the choroid plexus of the ventricles (fluid-filled spaces) inside the brain. From there, it circulates through the ventricular system and around the outside of the brain and spinal cord before being absorbed back into the bloodstream. CSF analysis is an important diagnostic tool for various neurological conditions, including infections, inflammation, and cancer.

In fish, there is a single membrane known as the primitive meninx. Amphibians and reptiles have two meninges, and birds and ... In anatomy, the meninges (/məˈnɪndʒiːz/, SG: meninx (/ˈmiːnɪŋks/ or /ˈmɛnɪŋks/), from Ancient Greek μῆνιγξ (mēninx) membrane ... "Definition of meninges". Merriam-Webster Online Dictionary. Retrieved 28 July 2012. "Definition of meninx". Merriam-Webster ... the space between the middle reticular meninges and the innermost tender meninges that lie close to the brain. It divides the ...
Meninges: The three membranes that cover the brain and spinal cord (singular: meninx). ... The outside meninx is called the dura mater, and is the most resilient of the three. The center layer is the arachnoid membrane ...
POC Meninx RS er en hjelm med fokus på komfort og beskyttelse. Hjelmen har en recco-reflektor, en liten transceiver som hjelper ...
... make the POC Meninx RS Mips ski helmet a perfect combination of form and function. ... Meninx RS Mips. Regular price €280,00 Outlet Sale Price A clean and simple appearance inspired by classic racing helmets belies ...
... make the POC Meninx RS Mips ski helmet a perfect combination of form and function. ... Meninx RS Mips. Regular price €280,00 Outlet Sale Price A clean and simple appearance inspired by classic racing helmets belies ...
Tissue membrane protein is prepared from whole tissue homogenates and presents a consistent pattern on SDS-PAGE analysis. The protein is stored in a buffer with protease inhibitor cocktail.
Learn about the different layers of the scalp and meninges in stunning 3D ... A crafty way of remembering the meninges of the brain is by using the mnemonic PAD; Pia, Arachnoid, Dura. Remember the meninges ... SNEAK PREVIEW: Scalp & Meninges detailed model. Posted on June 29, 2020. May 13, 2021. by Ellie Fahy , 3 min read ... The meninges are found beneath the cranial bones. They consist of three membranes which surround and protect the central ...
Figure 3. The meninges is often segmented as gray matter by the state-of-the-art image processing algorithms, including (a) ... This entry was posted in On Homepage Billboard, Posts and tagged alzheimers, ants, BA35, brain, Meninges, research, ... Accounting for the Confound of Meninges in Segmenting Entorhinal and Perirhinal Cortices in T1-weighted MRI. Posted on October ... The dura mater has similar intensity to gray matter (GM) in T1 contrast (Figure 2a). By contrast, in T2w MRI, meninges are easy ...
Barrier Properties of the Spinal Meninges Are Markedly Decreased by Freezing Meningeal Tissues Susan J. Thompson, MD, PhD; ... The principal barrier to diffusion in the meninges has been shown histologically [9,10]and functionally [2]to be within the ... After allowing 30 min for equilibration to 37 [degree sign]C, the study drug was added to the epidural side of the meninges. ... The rate at which a study drug diffuses through the meninges from a donor reservoir to the recipient reservoir is quantified to ...
Meninges. The spinal cord is surrounded by three membranes (dura mater, arachnoid mater and pia mater; Fig. 8.34), which are ... arachnoid is connected to the pia mater by numerous delicate strands that cross the subarachnoid space between the two meninges ... Meninges, Dura mater, Arachnoid mater, Pia mater ... continuous through the foramen magnum with the cranial meninges ...
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Posterior: Squamous occipital bone.. Anterior: Basi occiput, petrous temporal.. Superior: Tentorium cerebelli.. Inferior: Squamous occipital bone.. ...
Question 4 What are meninges. What is their function? Question 5 Name the three regions of brain? Question 6 What are the ...
Meninges covers the dura mater, arachnoid mater, and pia mater, which protect the spinal cord and contain cerebrospinal fluid. ...
II. Lesions in Meninges and Ventricular System B. Subdural Hemorrhage (cont). Chronic subdural hemorrhage is common in infants, the elderly, alcoholics, epileptics and demented individuals. Contributing factors include frequent head trauma and an enlarged subdural space (due to cerebral atrophy), providing less support for veins traversing this space. Chronic subdural hemorrhage follows mild trauma (sometimes forgotten by the patient) and symptoms may not occur for weeks to months after the trauma due to the slow rate of blood accumulation. Symptoms include seizures, headaches, confusion, behavioral changes, and signs of increased intracranial pressure; neurological signs may mimic those of degenerative disorders or neoplasms. Among diagnostic tests, CT scan or MRI is the most useful. 3. Pathology. The hematoma is encapsulated by a pseudomembrane composed of granulation tissue derived from the inflammatory reaction in the dura. The membrane forms initially at the clot surface facing the dura and ...
Learn about the different layers of the scalp and meninges in stunning 3D ... A crafty way of remembering the meninges of the brain is by using the mnemonic PAD; Pia, Arachnoid, Dura. Remember the meninges ... SNEAK PREVIEW: Scalp & Meninges detailed model. Posted on June 29, 2020. May 13, 2021. by Ellie Fahy , 3 min read ... The meninges are found beneath the cranial bones. They consist of three membranes which surround and protect the central ...
An all-encompassing protective layer, the Meninx is as influenced by science, and the bodys own meninges which protect the ... An all-encompassing protective layer, the Meninx is as influenced by science, and the bodys own meninges which protect the ...
encoded search term (Arteries to the Brain and Meninges) and Arteries to the Brain and Meninges What to Read Next on Medscape ... Arteries to the Brain and Meninges. Updated: Aug 06, 2013 * Author: Qing Hao, MD, PhD; Chief Editor: Selim R Benbadis, MD more ... Upon exiting the cavernous sinus, the ICA extends through the meninges to become the supraclinoid segment. The supraclinoid or ...
encoded search term (Arteries to the Brain and Meninges) and Arteries to the Brain and Meninges What to Read Next on Medscape ... Arteries to the Brain and Meninges. Updated: Aug 06, 2013 * Author: Qing Hao, MD, PhD; Chief Editor: Selim R Benbadis, MD more ... Upon exiting the cavernous sinus, the ICA extends through the meninges to become the supraclinoid segment. The supraclinoid or ...
The deepest layer of the meninges is called the __________. The answer is : Pia Mater ...
Detailed explanation-1: -The spinal cord and its meningeal coverings (dura mater, arachnoid mater, and pia mater) lie within the vertebral canal, a hollow space that runs inside the spinal vertebrae. Detailed explanation-2: -Epidural space-fatty space between the bony framework of the spinal vertebral column and the thick dura mater surrounding the spinal cord. It contains adipose tissue and blood vessels ...
Normal Anatomy of the Brain, Spinal Cord and Meninges - exhR0073. *Anatomia Normal do Cérebro, Medula Espinhal e Meninges - ... meninges, meninx, no, pia, sinus, sinuses, space, spinal, sub-arachnoid, subarachnoid, vascular, vein, veinous, veins, venous, ... This medical illustration series depicts a cross-sectional view of the normal anatomy of the brain, spinal cord and meninges. ...
Meninges, falces, and spaces. Meninges. *Three layers of connective tissue that cover and protect the brain and the spinal cord ... The meninges comprise the three protective membranes that envelop the central nervous system, i.e. the brain and spinal cord. ... For more information, see "Blood-brain barrier" and "Blood-cerebrospinal fluid barrier" in "The cerebral cortex, meninges, ...
Meninx RS Mips Helmet. 4 colors. $140.00 - $280.00. Up to 50% off ...
... of the meninges. In association with CD34, ALDH1 expression had a specificity and positive predictive value of 100%. We show ... ALDH1 is an immunohistochemical diagnostic marker for solitary fibrous tumours and haemangiopericytomas of the meninges ...
CDC assessed the value of the Fungitell beta-D-glucan (BDG) test for diagnostics and for monitoring response to treatment of patients in this outbreak. To test diagnostics, we evaluated 108 incident CSF samples from proven or probable case patients. Of 41 samples from proven cases, BDG levels of 40 samples were ,230 picograms/ml, and 1 was 205 pg/ml. Of 67 samples from probable cases, BDG levels were ,230 pg/ml for 30 samples, 139-195 pg/ml for 2 samples, and ,138 pg/ml for 35 samples. To test the value of the BDG assay in monitoring response to treatment, BDG levels were assessed in serial CSF samples collected from 20 patients. We found that among patients in whom CSF BDG levels progressively declined, most remained asymptomatic after completing antifungal therapy. Patients in whom CSF BDG levels remained persistently high had poor outcomes, although the number of patients in this group was small.. The full results of the study performed to validate this Beta-D-glucan test are available ...
By releasing the meninges properly you will also help all the membranes of the body, help modify the tensions inside the ... 2- It is not easy to work on every fiber in every direction of the intracranial meninges. Beryl E. Arbuckle, DO, FACOP, one of ... The specific tensegrity work on the cranial meninges is extremely important, for example, for conditions such as motor vehicle ... We will use a curved biotensegrity model to release the intracranial meninges. ...
Meninges. *Meningeal biopsy. Spinal cord and spinal canal. *Spinal decompression. *Discectomy. *Intervertebral disc ...
Brain or meninges, metastatic malignancy to it (also code primary site). C79.5. Bone or bone marrow, metastatic malignancy to ... Brain or meninges, metastatic malignancy to it (also code primary site). From CCMDB Wiki ... Retrieved from "https://ccmdb.kuality.ca/index.php?title=Brain_or_meninges,_metastatic_malignancy_to_it_(also_code_primary_site ...

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