Labyrinth Diseases: Pathological processes of the inner ear (LABYRINTH) which contains the essential apparatus of hearing (COCHLEA) and balance (SEMICIRCULAR CANALS).Vestibule, Labyrinth: An oval, bony chamber of the inner ear, part of the bony labyrinth. It is continuous with bony COCHLEA anteriorly, and SEMICIRCULAR CANALS posteriorly. The vestibule contains two communicating sacs (utricle and saccule) of the balancing apparatus. The oval window on its lateral wall is occupied by the base of the STAPES of the MIDDLE EAR.Ear, Inner: The essential part of the hearing organ consists of two labyrinthine compartments: the bony labyrinthine and the membranous labyrinth. The bony labyrinth is a complex of three interconnecting cavities or spaces (COCHLEA; VESTIBULAR LABYRINTH; and SEMICIRCULAR CANALS) in the TEMPORAL BONE. Within the bony labyrinth lies the membranous labyrinth which is a complex of sacs and tubules (COCHLEAR DUCT; SACCULE AND UTRICLE; and SEMICIRCULAR DUCTS) forming a continuous space enclosed by EPITHELIUM and connective tissue. These spaces are filled with LABYRINTHINE FLUIDS of various compositions.Semicircular Canals: Three long canals (anterior, posterior, and lateral) of the bony labyrinth. They are set at right angles to each other and are situated posterosuperior to the vestibule of the bony labyrinth (VESTIBULAR LABYRINTH). The semicircular canals have five openings into the vestibule with one shared by the anterior and the posterior canals. Within the canals are the SEMICIRCULAR DUCTS.Placenta: A highly vascularized mammalian fetal-maternal organ and major site of transport of oxygen, nutrients, and fetal waste products. It includes a fetal portion (CHORIONIC VILLI) derived from TROPHOBLASTS and a maternal portion (DECIDUA) derived from the uterine ENDOMETRIUM. The placenta produces an array of steroid, protein and peptide hormones (PLACENTAL HORMONES).Placentation: The development of the PLACENTA, a highly vascularized mammalian fetal-maternal organ and major site of transport of oxygen, nutrients, and fetal waste products between mother and FETUS. The process begins at FERTILIZATION, through the development of CYTOTROPHOBLASTS and SYNCYTIOTROPHOBLASTS, the formation of CHORIONIC VILLI, to the progressive increase in BLOOD VESSELS to support the growing fetus.Endolymphatic Duct: The part of the membranous labyrinth that traverses the bony vestibular aqueduct and emerges through the bone of posterior cranial fossa (CRANIAL FOSSA, POSTERIOR) where it expands into a blind pouch called the endolymphatic sac.Vestibular Diseases: Pathological processes of the VESTIBULAR LABYRINTH which contains part of the balancing apparatus. Patients with vestibular diseases show instability and are at risk of frequent falls.Vestibular Nucleus, Lateral: Vestibular nucleus lying immediately superior to the inferior vestibular nucleus and composed of large multipolar nerve cells. Its upper end becomes continuous with the superior vestibular nucleus.Vestibular Nuclei: The four cellular masses in the floor of the fourth ventricle giving rise to a widely dispersed special sensory system. Included is the superior, medial, inferior, and LATERAL VESTIBULAR NUCLEUS. (From Dorland, 27th ed)Petrous Bone: The dense rock-like part of temporal bone that contains the INNER EAR. Petrous bone is located at the base of the skull. Sometimes it is combined with the MASTOID PROCESS and called petromastoid part of temporal bone.Caloric Tests: Elicitation of a rotatory nystagmus by stimulating the semicircular canals with water or air which is above or below body temperature. In warm caloric stimulation a rotatory nystagmus is developed toward the side of the stimulated ear; in cold, away from the stimulated side. Absence of nystagmus indicates the labyrinth is not functioning.Vestibular Nerve: The vestibular part of the 8th cranial nerve (VESTIBULOCOCHLEAR NERVE). The vestibular nerve fibers arise from neurons of Scarpa's ganglion and project peripherally to vestibular hair cells and centrally to the VESTIBULAR NUCLEI of the BRAIN STEM. These fibers mediate the sense of balance and head position.Endolymphatic Sac: The blind pouch at the end of the endolymphatic duct. It is a storage reservoir for excess ENDOLYMPH, formed by the blood vessels in the membranous labyrinth.Trophoblasts: Cells lining the outside of the BLASTOCYST. After binding to the ENDOMETRIUM, trophoblasts develop into two distinct layers, an inner layer of mononuclear cytotrophoblasts and an outer layer of continuous multinuclear cytoplasm, the syncytiotrophoblasts, which form the early fetal-maternal interface (PLACENTA).Hydrocharitaceae: A plant family of the order Hydrocharitales, subclass ALISMATIDAE, class Liliopsida (monocotyledons).Fenestration, Labyrinth: The surgical creation of a new opening in the labyrinth of the ear for the restoration of hearing in cases of OTOSCLEROSIS. (Dorland, 27th ed)Cochlea: The part of the inner ear (LABYRINTH) that is concerned with hearing. It forms the anterior part of the labyrinth, as a snail-like structure that is situated almost horizontally anterior to the VESTIBULAR LABYRINTH.Endolymph: The lymph fluid found in the membranous labyrinth of the ear. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)Embryo Loss: Early pregnancy loss during the EMBRYO, MAMMALIAN stage of development. In the human, this period comprises the second through eighth week after fertilization.Reflex, Vestibulo-Ocular: A reflex wherein impulses are conveyed from the cupulas of the SEMICIRCULAR CANALS and from the OTOLITHIC MEMBRANE of the SACCULE AND UTRICLE via the VESTIBULAR NUCLEI of the BRAIN STEM and the median longitudinal fasciculus to the OCULOMOTOR NERVE nuclei. It functions to maintain a stable retinal image during head rotation by generating appropriate compensatory EYE MOVEMENTS.Cochlear Diseases: Pathological processes of the snail-like structure (COCHLEA) of the inner ear (LABYRINTH) which can involve its nervous tissue, blood vessels, or fluid (ENDOLYMPH).Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.Labyrinthitis: Inflammation of the inner ear (LABYRINTH).Vertigo: An illusion of movement, either of the external world revolving around the individual or of the individual revolving in space. Vertigo may be associated with disorders of the inner ear (EAR, INNER); VESTIBULAR NERVE; BRAINSTEM; or CEREBRAL CORTEX. Lesions in the TEMPORAL LOBE and PARIETAL LOBE may be associated with FOCAL SEIZURES that may feature vertigo as an ictal manifestation. (From Adams et al., Principles of Neurology, 6th ed, pp300-1)

*  The Effects of Gevokizumab in Corticosteroid-resistant Subjects With Autoimmune Inner Ear Disease - Full Text View -...

Meniere's Disease. Sudden Sensorineural Hearing Loss. Additional relevant MeSH terms: Ear Diseases. Labyrinth Diseases. ... Genetic and Rare Diseases Information Center resources: Sudden Sensorineural Hearing Loss Autoimmune Inner Ear Disease ... The Effects of Gevokizumab in Corticosteroid-resistant Subjects With Autoimmune Inner Ear Disease. This study has been ... An Open-label Study of the Effects of Gevokizumab in Corticosteroid-resistant Subjects With Autoimmune Inner Ear Disease. ...

*  Effectiveness of Osteopathic Manipulative Treatment (OMT) and Vestibular Rehabilitation Therapy (VRT) in Individuals With...

Labyrinth Diseases. Vestibular Diseases. Ear Diseases. Otorhinolaryngologic Diseases. Neurologic Manifestations. Nervous System ... Menieres disease. *Neurological conditions (including Peripheral Neuropathy, Stroke, traumatic brain injury, cerebral aneurysm ...

*  Transtympanic Gentamicin vs. Steroids in Refractory Meniere's Disease - Full Text View -

Meniere Disease. Endolymphatic Hydrops. Labyrinth Diseases. Ear Diseases. Otorhinolaryngologic Diseases. Prednisolone acetate. ... Steroids in Refractory Meniere's Disease. The safety and scientific validity of this study is the responsibility of the study ... Patients with Ménière's disease in later stages (not having vertigo attacks).. *Age: patients older than 70 years at the start ... Meniere's disease is characterised by episodic spontaneous vertigo attacks with hearing loss, ringing sounds and fullness in ...

*  Transtympanic Gentamicin vs. Steroids in Refractory Meniere's Disease - Full Text View -

Meniere Disease. Endolymphatic Hydrops. Labyrinth Diseases. Ear Diseases. Otorhinolaryngologic Diseases. Prednisolone acetate. ... Patients with Ménière's disease in later stages (not having vertigo attacks).. *Age: patients older than 70 years at the start ... MedlinePlus related topics: Meniere's Disease Drug Information available for: Methylprednisolone Gentamicin Gentamicin ... Meniere's disease is characterised by episodic spontaneous vertigo attacks with hearing loss, ringing sounds and fullness in ...

*  Efficacy of Vitamin D and Calcium Supplementation on the Prevention of Recurrences in BPPV - Full Text View -

Disease Attributes. Pathologic Processes. Vestibular Diseases. Labyrinth Diseases. Ear Diseases. Otorhinolaryngologic Diseases ... Nervous System Diseases. Signs and Symptoms. Sensation Disorders. Vitamins. Vitamin D. Ergocalciferols. Cholecalciferol. ...

*  Evaluation of a Sensory Enrichment Multimodal Device (SEMD) on Physical Therapy Patients With Disequilibrium - Full Text View -...

Condition or disease Intervention/treatment Vestibular Diseases Labyrinth Diseases Ear Diseases Otorhinolaryngologic Diseases ... Labyrinth Diseases. Labyrinthitis. Brain Diseases. Central Nervous System Diseases. Nervous System Diseases. Craniocerebral ... Ear Diseases. Brain Injuries. Brain Injuries, Traumatic. Vestibular Diseases. Otorhinolaryngologic Diseases. ...

*  Effectiveness of the Epley Manoeuvre Performed in Primary Care to Treat Benign Paroxysmal Positional Vertigo - Full Text View -...

Labyrinth Diseases. Ear Diseases. Otorhinolaryngologic Diseases. Neurologic Manifestations. Nervous System Diseases. Signs and ... Previous or current diagnoses of labyrinth's diseases such as Meniere's disease, labyrinthitis or vestibular neuronitis. ... Condition or disease Intervention/treatment Benign Positional Paroxysmal Vertigo Procedure: PROCEDURE: EPLEY MANOEUVRE ... Paget's disease, morbid obesity, ankylosing spondylitis, severe lumbar dysfunction and spinal cord injuries. ...

*  Nuclear, Plasma, and Radiological Engineering - Research Output - University of Illinois at Urbana-Champaign

Marjanovic, M., Nolan, R. M., Erickson-Bhatt, S. J., Adie, S. G., Chaney, E. J., South, F. A., Monroy, G. L., Shemonski, N. D., Shelton, R. L., Bower, A. J., Simpson, D. G., Ray, P. S., Cradock, K. A., Liu, Z. G. & Boppart, S. A. Apr 18 2016 Clinical and Translational Biophotonics, Translational 2016. OSA - The Optical Society. Research output: Chapter in Book/Report/Conference proceeding › Conference contribution ...




VESTIBULAIRE AFWIJKINGEN VESTIBULAR DISORDERS LABYRINTH DISEASES CALORISCHE (TEMPERATUUR) STIMULATIE DRAAISTOELONDERZOEK. Zie ... Tricuspid Valve Disease Resources on the Internet *Tricuspid Valve Disease *CTSN: Tricuspid Valve Disease *CTSN: A-V Valve ... Health: Diseases and Conditions: Tropical Diseases *VBC Tropical Disease Papers *Gruesome Pictures! Parasitology and Tropical ... Zie ook: FEMALE GENITAL DISEASES. Zie ook: VAGINAL DISEASES. Zie ook: VAGINITIS. *Trichomonas *Trichomoniasis TRICHOPTILOSIS ...

*  Deafness | definition of deafness by Medical dictionary

labyrinthine deafness that due to disease of the labyrinth.. Michel's deafness congenital deafness due to total lack of ... observations Many conditions and diseases may result in hearing loss. More than 21 million people in the United States have ... pagetoid deafness that occurring in osteitis deformans of the bones of the skull (paget's disease). ... with partial aplasia of the bony and membranous labyrinth and a resultant flattened cochlea. ...

*  Using Positron Emission Tomography to Predict Intracranial Tumor Growth in Neurofibromatosis Type II Patients - Full Text View ...

Peripheral Nervous System Diseases. Neuromuscular Diseases. Labyrinth Diseases. Ear Diseases. Otorhinolaryngologic Diseases. ... Neurodegenerative Diseases. Genetic Diseases, Inborn. Peripheral Nervous System Neoplasms. Nervous System Neoplasms. ... Nervous System Diseases. Neurofibromatoses. Neurofibroma. Vestibular Diseases. Neurofibromatosis 2. Nerve Sheath Neoplasms. ... Genetic and Rare Diseases Information Center resources: Neurofibromatosis Neurofibroma Acoustic Neuroma Schwannoma ...

*  Verapamil vs. Sertraline for Vestibular Migraine & Chronic Subjective Dizziness - Full Text View -

Vestibular Diseases. Labyrinth Diseases. Ear Diseases. Otorhinolaryngologic Diseases. Sertraline. Verapamil. Antidepressive ... Brain Diseases. Central Nervous System Diseases. Nervous System Diseases. Sensation Disorders. Neurologic Manifestations. Signs ... Condition or disease Intervention/treatment Phase Vestibular Migraine Chronic Subjective Dizziness Drug: Verapamil Drug: ...

*  Prednisone Treatment for Vestibular Neuronitis - Full Text View -

Labyrinth Diseases. Ear Diseases. Otorhinolaryngologic Diseases. Vestibulocochlear Nerve Diseases. Retrocochlear Diseases. ... Autoimmune Diseases of the Nervous System. Demyelinating Diseases. Peripheral Nervous System Diseases. Neuromuscular Diseases. ... Autoimmune Diseases. Immune System Diseases. Prednisone. Anti-Inflammatory Agents. Glucocorticoids. Hormones. Hormones, Hormone ... Vestibular Diseases. Vestibular Neuronitis. Guillain-Barre Syndrome. Neuritis. ...

*  Neural Mechanisms Engaged in Control of Eye Movements - Full Text View -

Vestibular Diseases. Neurodegenerative Diseases. Labyrinth Diseases. Ear Diseases. Otorhinolaryngologic Diseases. Nervous ... Degenerative CNS diseases, extrapyramidal disorders, Spino-cerebellar ataxias, Cerebrovascular diseases, demyelinating diseases ... Subjects with eye disease such as corneal or scleral abrasion or disease, glaucoma, refractive errors greater than 2 diopters. ... Degenerative Diseases of the Central Nervous System Ocular-motor and Vestibular Diseases ...

*  Effects of Prismatic Spectacle Lenses on Symptoms of Dizziness, Headache and Anxiety as Caused by Vertical Heterophoria - Full...

Nervous System Diseases. Signs and Symptoms. Sensation Disorders. Vestibular Diseases. Labyrinth Diseases. Ear Diseases. ... Genetic and Rare Diseases Information Center resources: Ocular Motility Disorders Motor Neuro-ophthalmic Disorders ...

*  Vestibular Rehabilitation and Dizziness - Full Text View -

Nervous System Diseases. Signs and Symptoms. Vestibular Diseases. Labyrinth Diseases. Ear Diseases. Otorhinolaryngologic ... There are parallels between the effects of age-related versus disease-related loss of vestibular function - in complaints of ... Dizziness is often related to vestibular disease which is treated effectively with vestibular exercises. Successful management ... progressive medical issues that would impact mobility (e.g., Parkinson's disease, cerebellar atrophy) ...

*  Full text of "Diseases Of The Nose Throat And Ear"

... See other formats THE LABYRINTH AND THE EIGHTH NERVE 397 however, the eighth ... 3. Haemorrhage into the labyrinth in the bleeding diseases should be excluded by an examination of the blood. Fig. 212. ...

*  Amblyopic nystagmus | definition of amblyopic nystagmus by Medical dictionary

... or to disease or injury to the labyrinth (labyrinth nystagmus); or to multiple sclerosis. Jerk nystagmus can also be induced ... injury or disease (e.g. Menière's disease) of the labyrinth or of the vestibulo-cochlear nerve (VIII). It presents as a jerk, ... Disease in many parts of the brain can result in nystagmus.. *Alcohol and drugs. Alcohol and some medications (e.g., anti- ... There are also cases of unknown origin (idiopathic nystagmus). See hereditary spinal ataxia; Wernicke's disease; foveation ...

*  Elliott Davin Kozin, M.D. | Harvard Catalyst Profiles | Harvard Catalyst

Models of Disease (MoD) Boot Camp Three-week course for clinical fellows starting basic/translational postdoctoral research. ... An enrichment program for PhD students on the fundamentals of human biology & disease. ... Kidney Diseases. *Kidney Transplantation. *Kinetics. *Labyrinth Diseases. *Laryngeal Neoplasms. *Laryngectomy. *Laryngostenosis ...

*  Susan King - Treading the Maze - OUT OF PRINT | Abecedarian Gallery

... a life-affirming journey through the labyrinth of disease.In Treading the Maze, Susan King embarks on two voyages, braving the ...

*  Epidemiology of benign paroxysmal positional vertigo: a population based study | Journal of Neurology, Neurosurgery & Psychiatry

16 Other inner ear diseases ipsilateral to the labyrinth affected by BPPV have been described in only 3% of patients.29 However ... Karlberg M, Hall K, Quickert N, et al. What inner ear diseases cause beinign paroxysmal positional vertigo? Acta Otolaryngol ... Benign paroxysmal positional vertigo is a recurring disease, with a recurrence rate of approximately 15% per year.19 We found ... This value probably reflects the natural course of the disease as only 8% of all participants with BPPV received effective ...


and The Stealth Killer: Is Oral Spirochetosis the Missing Link in the Dental and Heart Disease Labyrinth?. .. These two books ... Alzheimer's disease is increasing at an exponential rate....along with the increasing incidence of Lyme disease in the ... He also connects the disease with Lyme disease and other infections. He explains how the cells of the brain have difficulty up ... Alzheimer's disease; bacteria; Borrelia burgdorferi; dementia; infection; Lyme disease; periodontal pathogen; spirochetes; ...

*  Salomon Moos - Wikipedia

His better known research involved diseases of the inner ears' labyrinth. Moos is credited with being the first physician to ... Uber Pilzinvasion des Labyrinths im Gofolge von Masern (Concerning fungal infection of the labyrinths in association with ... Among his better known written works was a translation of Joseph Toynbee's "Diseases of the Ear" as Lehrbuch der ... point out that in certain infectious diseases, micro-organisms within the labyrinth negatively affect hearing and equilibrium. ...

*  Roller coaster 06/16/2013 GFX Definition of the Day

London Fields long looting loquacity lorry lottery louse Louvre lower lucas ludicrous speed luge lunar lunch lupus lyme disease ... kite Klondike knee knee defender kneel knife Knight knighted knowledge Kurd Kurdish Kurdistan kyderby laboratory labyrinth ... dinosaurs diplomat direct direction director dirigible disagree disappear disapprove disbar discipline disclosure Disease ...

Autoimmune inner ear disease: Autoimmune inner ear disease is a suspected autoimmune disease characterized by rapidly progressive bilateral sensorineural hearing loss.Inner Ear, Autoimmune (eMedicine, 2006) It occurs when the body's immune system attacks cells in the inner ear that are mistaken for a virus or bacteria.Vestibular system: The vestibular system, in most mammals, is the sensory system that provides the leading contribution about the sense of balance and spatial orientation for the purpose of coordinating movement with balance. Together with the cochlea, a part of the auditory system, it constitutes the labyrinth of the inner ear in most mammals, situated in the vestibulum in the inner ear (Figure 1).Placenta: The placenta (also known as afterbirth) is an organ that connects the developing fetus to the uterine wall to allow nutrient uptake, waste elimination, and gas exchange via the mother's blood supply, fight against internal infection and produce hormones to support pregnancy. The placenta provides oxygen and nutrients to growing babies and removes waste products from the baby's blood.Dog healthMedial vestibular nucleus: The medial vestibular nucleus is one of the vestibular nuclei. It is located in the medulla oblongata.Endolymphatic sac tumor: An endolymphatic sac tumor is a very uncommon papillary epithelial neoplasm arising within the endolymphatic sac or endolymphatic duct. This tumor shows a very high association with von Hippel-Lindau syndrome (VHL).Trophoblast: Trophoblasts (from Greek trephein: to feed, and blastos: germinator) are cells forming the outer layer of a blastocyst, which provide nutrients to the embryo and develop into a large part of the placenta. They are formed during the first stage of pregnancy and are the first cells to differentiate from the fertilized egg.Lagarosiphon major: Lagarosiphon major is a monocotic aquatic plant native to Southern Africa. Common names include African elodea, curly waterweed, oxygen weed and South African oxygen weed.Endolymph: Endolymph is the fluid contained in the membranous labyrinth of the inner ear. It is also called Scarpa's fluid, after Antonio Scarpa.Vision in fishes: Vision is an important sensory system for most species of fish. Fish eyes are similar to terrestrial vertebrates like birds and mammals, but have a more spherical lens.Prenatal nutrition: Nutrition and weight management before and during :pregnancy has a profound effect on the development of infants. This is a rather critical time for healthy fetal development as infants rely heavily on maternal stores and nutrient for optimal growth and health outcome later in life.LabyrinthitisVertigo (Marvel Comics): Vertigo is a native of the Savage Land who obtained superhuman powers at a young age by genetic engineering. Her powers enable her to render a person severely dizzy and even unconscious.

(1/121) 3D MRI of the membranous labyrinth. An age related comparison of MR findings in patients with labyrinthine fibrosis and in persons without inner ear symptoms.

PURPOSE: We compared MRI of the membranous labyrinth in patients with chronic non-neoplastic inner ear disease and MR signs of labyrinthine fibrosis and controls depending on their age, in order to establish whether there were any MR differences regarding patient age groups, control age groups and between the patients and controls themselves. MATERIALS AND METHODS: Clinical ENT examinations as well as a T2* weighted 3D CISS (Constructive Interference in Steady State) sequence with a slice thickness of 0.7 mm were performed. Our collective was subdivided as follows: 0-19 years (10 controls, 3 patients with chronic non-neoplastic inner ear disease), 20-49 years (55 controls, 8 patients), 50 years and older (40 controls, 22 patients). Detectability of labyrinthine structures (e.g. cochlea, vestibule, semicircular canals) and filling defects were evaluated. RESULTS: In the 3 age-groups of the control collective no significant differences were observed in the membranous labyrinth. However differences concerning labyrinthine detectability emerged between controls and patients in both the 20-49 years and 50 years and older age groups. In the patient collective the 3 age groups showed no significant discrepancy in the mean number of lesions. CONCLUSION: Filling defects of the membranous labyrinth on 3D CISS MR images are pathological even in older persons. We would therefore recommend high resolution T2* weighted MRI in the case of suspected labyrinthine fibrosis.  (+info)

(2/121) Sound- and pressure-induced vertigo associated with dehiscence of the roof of the superior semicircular canal.

In many types of peripheral vertigo, imaging is not part of the initial evaluation. We present a patient with sound- and pressure-induced vertigo associated with bony dehiscence of the roof of the superior semicircular canal. The diagnosis of this new entity can only be made by high-resolution coronal CT imaging of the temporal bones. In patients with this symptom complex, CT should be performed early in the diagnostic workup.  (+info)

(3/121) Cavernous angioma of the internal acoustic meatus--case report.

A 39-year-old female presented with an intrameatal cavernous angioma manifesting as hearing loss and tinnitus in the right ear which progressed over 8 months. Magnetic resonance (MR) images revealed an intrameatal lesion as ultra-high intensity, nearly as bright as cerebrospinal fluid, on the T2-weighted images, and isointensity on the T1-weighted images. Computed tomography (CT) showed the mass accompanied by stippled patterns of calcification. The patient underwent surgery under a diagnosis of calcified acoustic neurinoma. Histological studies were compatible with cavernous angioma. Intrameatal cavernous angioma is a rare disease which requires differential diagnosis from the more common neurinoma or meningioma in this location. Intrameatal lesion with ultra-high intensity on T2-weighted MR imaging and stippled patterns of calcification on CT is more likely to be cavernous angioma than acoustic neurinoma. These neuroimaging features are important information in deciding the treatment strategy.  (+info)

(4/121) Coriolis-force-induced trajectory and endpoint deviations in the reaching movements of labyrinthine-defective subjects.

When reaching movements are made during passive constant velocity body rotation, inertial Coriolis accelerations are generated that displace both movement paths and endpoints in their direction. These findings directly contradict equilibrium point theories of movement control. However, it has been argued that these movement errors relate to subjects sensing their body rotation through continuing vestibular activity and making corrective movements. In the present study, we evaluated the reaching movements of five labyrinthine-defective subjects (lacking both semicircular canal and otolith function) who cannot sense passive body rotation in the dark and five age-matched, normal control subjects. Each pointed 40 times in complete darkness to the location of a just extinguished visual target before, during, and after constant velocity rotation at 10 rpm in the center of a fully enclosed slow rotation room. All subjects, including the normal controls, always felt completely stationary when making their movements. During rotation, both groups initially showed large deviations of their movement paths and endpoints in the direction of the transient Coriolis forces generated by their movements. With additional per-rotation movements, both groups showed complete adaptation of movement curvature (restoration of straight-line reaches) during rotation. The labyrinthine-defective subjects, however, failed to regain fully accurate movement endpoints after 40 reaches, unlike the control subjects who did so within 11 reaches. Postrotation, both groups' movements initially had mirror image curvatures to their initial per-rotation reaches; the endpoint aftereffects were significantly different from prerotation baseline for the control subjects but not for the labyrinthine-defective subjects reflecting the smaller amount of endpoint adaptation they achieved during rotation. The labyrinthine-defective subjects' movements had significantly lower peak velocity, higher peak elevation, lower terminal velocity, and a more vertical touchdown than those of the control subjects. Thus the way their reaches terminated denied them the somatosensory contact cues necessary for full endpoint adaptation. These findings fully contradict equilibrium point theories of movement control. They emphasize the importance of contact cues in adaptive movement control and indicate that movement errors generated by Coriolis perturbations of limb movements reveal characteristics of motor planning and adaptation in both healthy and clinical populations.  (+info)

(5/121) Dumbbell schwannomas of the internal auditory canal.

BACKGROUND AND PURPOSE: Benign tumors of the internal auditory canal (IAC) may leave the confines of the IAC fundus and extend into inner ear structures, forming a dumbbell-shaped lesion. It is important to differentiate dumbbell lesions, which include facial and vestibulocochlear schwannomas, from simple intracanalicular schwannomas, as surgical techniques and prognostic implications are affected. In this article, the imaging and clinical features of these dumbbell schwannomas are described. METHODS: A dumbbell lesion of the IAC is defined as a mass with two bulbous segments, one in the IAC fundus and the other in the membranous labyrinth of the inner ear or the geniculate ganglion of the facial nerve canal, spanned by an isthmus. Twenty-four patients with dumbbell lesions of the IAC had their clinical and imaging data retrospectively reviewed. Images were evaluated for contour of the mass and extension into the membranous labyrinth or geniculate ganglion. RESULTS: Ten of 24 lesions were facial nerve dumbbell lesions. Characteristic features included an enhancing "tail" along the labyrinthine segment of the facial nerve and enlargement of the facial nerve canal. Dumbbell schwannomas of the vestibulocochlear nerve (14/24) included transmodiolar (8/14), which extended into the cochlea, transmacular (2/14), which extended into the vestibule, and combined transmodiolar/transmacular (4/14) types. CONCLUSION: Simple intracanalicular schwannomas can be differentiated from transmodiolar, transmacular, and facial nerve schwannomas with postcontrast and high-resolution fast spin-echo T2-weighted MR imaging. Temporal bone CT is reserved for presurgical planning in the dumbbell facial nerve schwannoma group.  (+info)

(6/121) Enhancement of the eighth cranial nerve and labyrinth on MR imaging in sudden sensorineural hearing loss associated with human herpesvirus 1 infection: case report.

The case of a 61-year-old woman who presented with herpes labialis, subclinical meningitis, and sudden onset of bilateral sensorineural hearing loss is presented. Contrast-enhanced MR imaging showed marked bilateral enhancement of the intracanalicular portion of the eighth cranial nerve, right cochlea, and left vestibule. Polymerase chain reaction was positive for human herpesvirus 1 obtained from the cerebral spinal fluid, which suggested the diagnosis of viral neuritis.  (+info)

(7/121) Positional down beating nystagmus in 50 patients: cerebellar disorders and possible anterior semicircular canalithiasis.

OBJECTIVES: To clarify the clinical significance of positional down beat nystagmus (pDBN). METHODS: A discussion of the neuro-otological findings in 50 consecutive patients with pDBN. RESULTS: In 38 patients there was evidence of CNS disease (central group) but in 12 there was not (idiopathic group). In the CNS group, presenting symptoms were gait, speech, and autonomic dysfunction whereas in the idiopathic group patients mostly reported positional vertigo. The main neurological and oculomotor signs in the CNS group were explained by cerebellar dysfunction, including 13 patients with multiple system atrophy. In patients with multiple system atrophy with a prominent extrapyramidal component, the presence of pDBN was helpful in the differential diagnosis of atypical parkinsonism. No patient with pDBN had the Arnold-Chiari malformation, a common cause of constant down beat nystagmus (DBN). In the idiopathic group, the pDBN had characteristics which suggested a peripheral labyrinthine disorder: vertigo, adaptation, and habituation. In six patients an additional torsional component was found (concurrently with the pDBN in three). Features unusual for peripheral disorder were: bilateral positive Dix-Hallpike manoeuvre in nine of 12 patients and selective provocation by the straight head-hanging manoeuvre in two. CONCLUSION: It is argued that some patients with idiopathic pDBN have benign paroxysmal positional vertigo (BPPV) with lithiasis of the anterior canal. The torsional component may be weak, because of the predominantly sagittal orientation of the anterior canal, and may not be readily seen clinically. Nystagmus provocation by bilateral Dix-Hallpike and straight head-hanging may be explained by the vertical upwards orientation of the ampullary segment of the anterior canal in the normal upright head position. Such orientation makes right-left specificity with the Dix-Hallpike manoeuvre less important than for posterior canal BPPV. This orientation requires a further downwards movement of the head, often achieved with the straight head-hanging position, to provoke migration of the canaliths. The straight head-hanging manoeuvre should be carried out in all patients with a history of positional vertigo and a negative Dix-Hallpike manoeuvre.  (+info)

(8/121) Vestibular information is required for dead reckoning in the rat.

Dead reckoning is an on-line form of spatial navigation used by an animal to identify its present location and return directly to a starting location, even after circuitous outward trips. At present, it is not known which of several self-movement cues (efferent copy from movement commands, proprioceptive information, sensory flow, or vestibular information) are used to compute homeward trajectories. To determine whether vestibular information is important for dead reckoning, the impact of chemical labyrinthectomy was evaluated in a test that demanded on-line computation of a homeward trajectory. Rats were habituated to leave a refuge that was visible from all locations on a circular table to forage for large food pellets, which they carried back to the refuge to eat. Two different probe trials were given: (1) the rats foraged from the same spatial location from a hidden refuge in the light and so were able to use visual cues to navigate; (2) the same procedure took place in the dark, constraining the animals to dead reckon. Although control rats carried food directly and rapidly back to the refuge on both probes, the rats with vestibular lesions were able to do so on the hidden refuge but not on the dark probe. The scores of vestibular reflex tests predicted the dead reckoning deficit. The vestibular animals were also impaired in learning a new piloting task. This is the first unambiguous demonstration that vestibular information is used in dead reckoning and also contributes to piloting.  (+info)


  • This is possible because the excess of pressure inside the inner ear is reduced by a break of the sacculum, in the vestibular labyrinth, with no long term consequence for the cochlea. (

membranous labyrinth

  • Mondini's deafness congenital deafness due to dysgenesis of the organ of Corti, with partial aplasia of the bony and membranous labyrinth and a resultant flattened cochlea. (
  • The inner ear has two parts: the bony labyrinth and the membranous labyrinth. (
  • The membranous labyrinth is contained within the bony labyrinth, and contains a fluid called endolymph. (
  • Between the outer wall of the membranous labyrinth and the wall of the bony labyrinth is the perilymphatic space which contains the perilymph. (
  • The membranous labyrinth is suspended in the perilymph. (


  • The perilymph in the bony labyrinth is continuous with the cerebrospinal fluid of the subarachnoid space via the perilymphatic duct. (


  • The snakeheads and the anabantoids are united by the presence of the labyrinth organ, which is a much-folded suprabranchial accessory breathing organ. (
  • The fish in the Anabantoidei suborder are known as anabantoids or labyrinth fish. (


  • Moos is credited with being the first physician to point out that in certain infectious diseases, micro-organisms within the labyrinth negatively affect hearing and equilibrium. (
  • The characteristics of the fish habitats are indicators of the size of the labyrinth organ, as the organ size is negatively correlated with the level of oxygen in the waters. (

Giant Gourami

  • 1995). Diseases of Giant Gourami, Osphronemus goramy (Lacepede) Archived January 6, 2007, at the Wayback Machine. (

autoimmune inner e

  • On the other hand, steroids are drug of choice for autoimmune inner ear disease and commonly used for sudden hearing loss. (
  • The purpose of this study is to determine if gevokizumab therapy may be an alternate therapy in patients with steroid resistant Autoimmune Inner Ear Disease. (

Meniere's Disease

  • This trial aims to compare transtympanic steroids against the standard treatment (transtympanic gentamicin) in refractory unilateral Meniere's disease. (
  • Meniere's disease is characterised by episodic spontaneous vertigo attacks with hearing loss, ringing sounds and fullness in the ear. (
  • These symptoms are not symptoms of Meniere's disease per se, but rather are side effects resulting from failure of the organ of hearing and balance, and include nausea, vomiting, and sweating-which are typically symptoms of vertigo, and not of Ménière's. (
  • EH, in turn, is strongly associated with developing MD, but not everyone with EH develops MD: "The relationship between endolymphatic hydrops and Meniere's disease is not a simple, ideal correlation. (


  • While Ménière's disease is chronic and progressive, Lermoyez's syndrome is an acute phenomenon which results in no damage for the ciliated cells of cochlea. (
  • The Labyrinth of Animals (1908) The Ear and its Diseases (1910) Otosclerosis (1917) The Mechanism of the Cochlea (1924) co-written with George Wilkinson Glasgow Post Office Directory 1868-69 BIOGRAPHICAL INDEX OF FORMER FELLOWS OF THE ROYAL SOCIETY OF EDINBURGH 1783 - 2002 (PDF). (


  • Phylogeny of families and genera in Anabatoidei based on mitochondrial DNA sequences: Several labyrinth fish are important food sources in their native countries. (


  • He made contributions in the research of diseases such as tuberculosis of the ear, otosclerosis, and otogenous meningitis. (


  • The cause of Ménière's disease is unclear but likely involves both genetic and environmental factors. (
  • The two may be linked by genetic factors or by vascular damage to the labyrinth. (

breathing organ

  • The labyrinth organ, a defining characteristic of fish in the suborder Anabantoidei, is a much-folded suprabranchial accessory breathing organ. (


  • Symptoms are believed to occur as the result of increased fluid build up in the labyrinth of the inner ear. (


  • His better known research involved diseases of the inner ears' labyrinth. (
  • Following the end of the war, Lumsden spent time in Rome studying the treatment of Ménière's disease by destruction of the labyrinth of the inner ear by ultrasound and in Britain introduced the treatment at the experimental stage. (
  • Ménière's disease (MD) is a disorder of the inner ear that is characterized by episodes of feeling like the world is spinning (vertigo), ringing in the ears (tinnitus), hearing loss, and a fullness in the ear. (
  • The initial triggers of Ménière's disease are not fully understood, with a variety of potential inflammatory causes that lead to endolymphatic hydrops (EH), a distension of the endolymphatic spaces in the inner ear. (


  • when referred to as a disease unto itself, it is also termed migraine-associated vertigo (MAV), migrainous vertigo, or migraine-related vestibulopathy. (


  • Ménière's disease - There is an increased prevalence of migraine in patients with Ménière's disease and migraine leads to a greater susceptibility of developing Ménière's disease. (


  • observations Many conditions and diseases may result in hearing loss. (
  • Disease in many parts of the brain can result in nystagmus. (
  • As a result, labyrinth fish can survive for a short period of time out of water, as they can inhale the air around them, provided they stay moist. (


  • A Pendergast ancestor, Hezekiah, built the family's fortune on an elixir that ultimately left users with ALS- or Huntington's disease-like symptoms. (


  • Labyrinth Fish. (
  • The Anabantoidei are a suborder of anabantiform ray-finned freshwater fish distinguished by their possession of a lung-like labyrinth organ, which enables them to breathe air. (
  • Some labyrinth fish are important food fish, and many others, such as the Siamese fighting fish and paradise fish, are popular as aquarium fish. (
  • This organ allows labyrinth fish to take in oxygen directly from the air, instead of taking it from the water in which they reside through use of gills. (
  • Labyrinth fish are not born with functional labyrinth organs. (
  • The development of the organ is gradual and most labyrinth fish breathe entirely with their gills and develop the labyrinth organs when they grow older. (
  • Labyrinth fish are endemic to fresh waters of Asia and Africa. (
  • In Africa, significantly smaller numbers of labyrinth fish can be found in the southern half of the continent, with concentrations in the rainforest waters. (
  • In general, the labyrinth fish are carnivores that eat small aquatic organisms and carrion. (
  • Labyrinth fish are well known for their bubble-nesting behavior, although some species do not build bubble nests and employ other methods of brooding. (
  • Other smaller labyrinth fish, such as the climbing perch, the kissing gourami, the snakeskin gourami, and other gouramies of the genus Trichogaster, are local food fish in Southeast Asia. (
  • The Siamese fighting fish is perhaps the most popular labyrinth fish in the aquarium trade. (
  • Many of the labyrinth fish are peaceful and do well in most community tanks. (


  • The Labyrinth of the Lost is a mirror maze. (
  • It was one of eight films shortlisted by Germany to be their submission for the Academy Award for Best Foreign Language Film at the 88th Academy Awards, but it lost out to Labyrinth of Lies. (


  • Bartram Forest also contains a stone labyrinth, used for meditative and other purposes. (


  • For several years, King Minos used his labyrinth to imprison his prisoners so that the Minotaur can kill them. (

Central Nervou


  • The Minotaur's corpse was later transported back to the labyrinth in Greece. (


  • Review by Kirkus Reviews Blue Labyrinth currently holds a 4.1/5 rating on Goodreads. (


  • Ménière's disease may go on for days or even years, while migraines typically do not last longer than 24 hours. (


  • Criteria for excluding subjects will include eye disease such as corneal or scleral abrasion or disease, glaucoma, refractive errors greater than 2 diopters and concurrent medication with CNS-active agents. (


  • With the help of Ariadne, Theseus made his way through the labyrinth and killed the Minotaur with his sword. (


  • Among his better known written works was a translation of Joseph Toynbee's "Diseases of the Ear" as Lehrbuch der Ohrenkrankheiten (1863). (


  • Tilda is told by her paediatrician Dr. Ehlers (Tilo Prückner) that visiting places the sick person knows well can help living with the disease. (


  • Species native to low-oxygen waters are more likely to have larger and more complex labyrinth organs than species found in fast-flowing, oxygen-rich waters. (


  • Because of his disease, Amandus causes a disaster which leads to Sarah moving out. (


  • Miklos Vryolak had suffered from an unknown disease which was beyond the cure of any medicine. (