Six-carbon saturated hydrocarbon group of the methane series. Include isomers and derivatives. Various polyneuropathies are caused by hexane poisoning.
Concentrated pharmaceutical preparations of plants obtained by removing active constituents with a suitable solvent, which is evaporated away, and adjusting the residue to a prescribed standard.
A plant genus of the family MYRSINACEAE. Members contain ardisiacrispins (oleanane triterpenoid saponins), ardicrenin, and cyclamiretin.
A plant genus of the family PIPERACEAE that includes species used for spicy and stimulating qualities.
A plant genus of the family CLUSIACEAE. Members contain costatolide, calanolides and 4-phenylfuranocoumarins (FUROCOUMARINS).
Liquids that dissolve other substances (solutes), generally solids, without any change in chemical composition, as, water containing sugar. (Grant & Hackh's Chemical Dictionary, 5th ed)
Anhydride polymers with a repeating structure of RC(=O)OC(=O)R. They readily hydrolyze in water making them useful for DELAYED-ACTION PREPARATIONS.
A plant species of the genus CITRUS, family RUTACEAE that provides the familiar lime fruit. Its common name of lime is similar to the limetree (TILIA).
A plant genus of the family CAPPARACEAE that contains cleogynol and 15alpha-acetoxycleomblynol (dammaranes) and 1-epibrachyacarpone (a triterpene), and ISOTHIOCYANATES.
The generic name for the group of aliphatic hydrocarbons Cn-H2n+2. They are denoted by the suffix -ane. (Grant & Hackh's Chemical Dictionary, 5th ed)
A resinous substance obtained from beehives that is used traditionally as an antimicrobial. It is a heterogeneous mixture of many substances.
A microanalytical technique combining mass spectrometry and gas chromatography for the qualitative as well as quantitative determinations of compounds.
'Bicyclo compounds' in medicinal chemistry refer to organic molecules containing two fused rings, where each ring shares two common atoms, creating a topological structure that resembles two overlapping circles or bicycle tires.
Viscous, nauseating oil obtained from the shrub Croton tiglium (Euphorbaceae). It is a vesicant and skin irritant used as pharmacologic standard for skin inflammation and allergy and causes skin cancer. It was formerly used as an emetic and cathartic with frequent mortality.
A plant genus of the family MYRTACEAE that bears an edible fruit and contains guavin B and quercetin glycosides.
Use of plants or herbs to treat diseases or to alleviate pain.
Picrates are salts of picric acid, an explosive organic compound previously used as a yellow dye and antiseptic, which are now primarily used in chemical research and industrial applications. Please note that picrates should be handled with care due to their potential explosiveness when heated or subjected to friction.
Drugs that selectively bind to and activate ADENOSINE A3 RECEPTORS.
Separation of a mixture in successive stages, each stage removing from the mixture some proportion of one of the substances, for example by differential solubility in water-solvent mixtures. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
The outer layer of the woody parts of plants.
Expanded structures, usually green, of vascular plants, characteristically consisting of a bladelike expansion attached to a stem, and functioning as the principal organ of photosynthesis and transpiration. (American Heritage Dictionary, 2d ed)
A plant genus of the family CELASTRACEAE. Members contain friedelane-type TRITERPENES and SESQUITERPENES, EUDESMANE.
Root-like underground horizontal stem of plants that produces shoots above and roots below. Distinguished from true roots which don't have buds and nodes. Similar to true roots in being underground and thickened by storage deposits.
A plant genus of the family EUPHORBIACEAE. The common name of dragon's blood is also used for DRACAENA and Daemonorops (ARECACEAE). Croton tiglium is the source of CROTON OIL.
Compounds that selectively bind to and block the activation of ADENOSINE A3 RECEPTORS.

Inhibitory effect of sulfur-containing compounds in Scorodocarpus borneensis Becc. on the aggregation of rabbit platelets. (1/196)

The inhibitory effects of three pure compounds isolated from wood garlic, 2,4,5-trithiahexane (I), 2,4,5,7-tetrathiaoctane (II), and 2,4,5,7-tetrathiaoctane 2,2-dioxide (III), on rabbit platelet aggregation induced by collagen, arachidonic acid, U46619, ADP (adenosine 5'-diphosphate), PAF (platelet aggregating factor), and thrombin were studied in vitro. The anti-aggregating activity of 2,4,5,7-tetrathiaoctane 4,4-dioxide (IV) was also measured with collagen and arachidonic acid. I, II, III, and IV inhibited the platelet aggregation induced by all tested agonists. I, II, and III exhibited a stronger inhibitory effect against the thrombin-induced aggregation of GFP (gel-filtered platelets) than against the aggregation induced by the other agonists. Notably, the IC50 value for III was 4 microM, which is approximately 2.5 times stronger than MATS (methyl allyl trisulfide), a major anti-platelet compound isolated from garlic. In inhibiting collagen-induced aggregation, II was as potent as MATS and aspirin, with a marked disaggregation effect on the secondary aggregation by arachidonic acid, at the rate of 47.05%/min at a concentration of 10(-4) M. I, II, and III also suppressed U46619-induced aggregation. These results suggest that sulfur-containing compounds in wood garlic not only inhibit arachidonic acid metabolism but also suppress aggregation in association with the function of the platelet plasma membrane.  (+info)

Chronic inhalation carcinogenicity study of commercial hexane solvent in F-344 rats and B6C3F1 mice. (2/196)

The carcinogenic and chronic toxicity potential of commercial hexane solvent was evaluated in F-344 rats and B6C3F1 mice (50/sex/concentration/species) exposed by inhalation for 6 h/day, 5 days/week for 2 years. Target hexane vapor concentrations were 0, 900, 3000, and 9000 ppm. There were no significant differences in survivorship between control and hexane-exposed groups, and clinical observations were generally unremarkable. Small, but statistically significant decreases in body weight gain were seen in rats of both sexes in the mid- and high-exposure groups and in high-expsoure female mice. The only noteworthy histopathological finding in rats was epithelial cell hyperplasia in the nasoturbinates and larynx of exposed groups. This response was judged to be indicative of upper respiratory tract tissue irritation. No significant differences in tumor incidence between control and hexane-exposed rats were found. In mice, uterine tissue from the high-exposure females exhibited a significant decrease in the severity of cystic endometrial hyperplasia compared to controls. An increase in the combined incidence of hepatocellular adenomas and carcinomas was observed in high-exposure female mice. The incidence of liver tumors was not increased in the mid- or low-exposure female mice or in male mice exposed to hexane. An increased incidence of pituitary adenomas was observed in female, but not male mice. This finding was not believed to have been treatment-related because the incidence in the control group was unusually low, and the incidence in exposed groups was not dose-related and was within the historical control range. No other neoplastic changes judged to be treatment-related were observed in tissues from male or female mice. In conclusion, chronic exposure to commercial hexane solvent at concentrations up to 9000 ppm was not carcinogenic to F-344 rats or to male B6C3F1 mice, but did result in an increased incidence of liver tumors in female mice.  (+info)

Crystal structure of triosephosphate isomerase from Trypanosoma cruzi in hexane. (3/196)

To gain insight into the mechanisms of enzyme catalysis in organic solvents, the x-ray structure of some monomeric enzymes in organic solvents was determined. However, it remained to be explored whether the structure of oligomeric proteins is also amenable to such analysis. The field acquired new perspectives when it was proposed that the x-ray structure of enzymes in nonaqueous media could reveal binding sites for organic solvents that in principle could represent the starting point for drug design. Here, a crystal of the dimeric enzyme triosephosphate isomerase from the pathogenic parasite Trypanosoma cruzi was soaked and diffracted in hexane and its structure solved at 2-A resolution. Its overall structure and the dimer interface were not altered by hexane. However, there were differences in the orientation of the side chains of several amino acids, including that of the catalytic Glu-168 in one of the monomers. No hexane molecules were detected in the active site or in the dimer interface. However, three hexane molecules were identified on the surface of the protein at sites, which in the native crystal did not have water molecules. The number of water molecules in the hexane structure was higher than in the native crystal. Two hexanes localized at <4 A from residues that form the dimer interface; they were in close proximity to a site that has been considered a potential target for drug design.  (+info)

Validation of a new procedure to determine plasma fatty acid concentration and isotopic enrichment. (4/196)

Assessment of free fatty acid (FFA) concentration and isotopic enrichment is useful for studies of FFA kinetics in vivo. A new procedure to recover the major FFA from plasma for concentration and isotopic enrichment measurements is described and validated. The procedure involves extraction of plasma lipids with hexane, methylation with iodomethane (CH(3)I) to form fatty acid methyl esters (FAME), and subsequent purification of FAME by solid phase extraction (SPE) chromatography. The new method was compared with a traditional method using thin-layer chromatography (TLC) to recover plasma FFA, with subsequent methylation by BF(3)/methanol. The TLC method was found to be less reliable than the new CH(3)I method because of contamination with extraneous fatty acids, chemical fractionation of FFA species, and incomplete recovery of FFA associated with TLC. In contrast, the CH(3)I/SPE method was free of contamination, did not exhibit chemical fractionation, and had higher recovery. The iodomethane reaction was specific for free fatty acids; no FAME were formed when esterified fatty acids (triglycerides, cholesteryl esters, phospholipids) were subjected to the methylation reaction. We conclude that the CH(3)I/SPE method provides rapid and convenient recovery of plasma fatty acids for quantification or GC/MS analysis as methyl esters, and is not subject to the problems of contamination, reduced recovery, and chemical fractionation associated with recovery of FFA by TLC.  (+info)

Defining a rob regulon in Escherichia coli by using transposon mutagenesis. (5/196)

The Rob protein of Escherichia coli is a member of the AraC-XylS family of prokaryotic transcriptional regulators and is expressed constitutively. Deletion of the rob gene increases susceptibility to organic solvents, while overexpression of Rob increases tolerance to organic solvents and resistance to a variety of antibiotics and to the superoxide-generating compound phenazine methosulfate. To determine whether constitutive levels of Rob regulate basal gene expression, we performed a MudJ transposon screen in a rob deletion mutant containing a plasmid that allows for controlled rob gene expression. We identified eight genes and confirmed that seven are transcriptionally activated by normal expression of Rob from the chromosomal rob gene (inaA, marR, aslB, ybaO, mdlA, yfhD, and ybiS). One gene, galT, was repressed by Rob. We also demonstrated by Northern analysis that basal expression of micF is significantly higher in wild-type E. coli than in a rob deletion mutant. Rob binding to the promoter regions of most of these genes was substantiated in electrophoretic mobility shift assays. However, Mu insertions in individual Rob-regulated genes did not affect solvent sensitivity. This phenotype may depend on changes in the expression of several of these Rob-regulated genes or on other genes that were not identified. Rob clearly affects the basal expression of genes with a broad range of functions, including antibiotic resistance, acid adaptation, carbon metabolism, cell wall synthesis, central intermediary metabolism, and transport. The magnitudes of Rob's effects are modest, however, and the protein may thus play a role as a general transcription cofactor.  (+info)

Anaerobic initial reaction of n-alkanes in a denitrifying bacterium: evidence for (1-methylpentyl)succinate as initial product and for involvement of an organic radical in n-hexane metabolism. (6/196)

A novel type of denitrifying bacterium (strain HxN1) with the capacity to oxidize n-alkanes anaerobically with nitrate as the electron acceptor to CO(2) formed (1-methylpentyl)succinate (MPS) during growth on n-hexane as the only organic substrate under strict exclusion of air. Identification of MPS by gas chromatography-mass spectrometry was based on comparison with a synthetic standard. MPS was not formed during anaerobic growth on n-hexanoate. Anaerobic growth with [1-(13)C]n-hexane or d(14)-n-hexane led to a 1-methylpentyl side chain in MPS with one (13)C atom or 13 deuterium atoms, respectively. This indicates that the 1-methylpentyl side chain originates directly from n-hexane. Electron paramagnetic resonance spectroscopy revealed the presence of an organic radical in n-hexane-grown cells but not in n-hexanoate-grown cells. Results point at a mechanistic similarity between the anaerobic initial reaction of n-hexane and that of toluene, even though n-hexane is much less reactive; the described initial reaction of toluene in anaerobic bacteria is an addition to fumarate via a radical mechanism yielding benzylsuccinate. We conclude that n-hexane is activated at its second carbon atom by a radical reaction and presumably added to fumarate as a cosubstrate, yielding MPS as the first stable product. When 2,3-d(2)-fumarate was added to cultures growing on unlabeled n-hexane, 3-d(1)-MPS rather than 2,3-d(2)-MPS was detected, indicating loss of one deuterium atom by an as yet unknown mechanism.  (+info)

Interactions of some organic solvents: hydrocarbons and chloroalkene. (7/196)

Metabolic and toxicodynamic interactions of some organic solvents in rats repeatedly treated with medium dose levels were examined. It was shown that both n-hexane and ethylbenzene significantly inhibited tetrachloroethylene metabolism during a 2-week period. n-Hexane and tetrachloroethylene enhanced metabolism of ethylbenzene whereas ethylbenzene suppressed n-hexane metabolism only at the end of the experiment. Biochemical changes, especially the drop in the level of non-protein sulfhydryl groups in tissues of rats treated with organic solvent mixtures, were significantly less pronounced than those observed after these chemicals were administered separately. These results demonstrate that metabolic interactions between hydrocarbons and chloroalkene may lead to a modification of the biological response to these compounds.  (+info)

Activation of enzymes for nonaqueous biocatalysis by denaturing concentrations of urea. (8/196)

Urea is one of the most commonly used denaturants of proteins. However, herein we report that enzymes lyophilized from denaturing concentrations of aqueous urea exhibited much higher activity in organic solvents than their native counterparts. Thus, instead of causing deactivation, urea effected unexpected activation of enzymes suspended in organic media. Activation of subtilisin Carlsberg (SC) in the organic solvents (hexane, tetrahydrofuran, and acetone) increased with increasing urea concentrations up to 8 M. Active-site titration results and activity assays indicated the presence of partially unfolded but catalytically active SC in 8 M urea; however, the urea-modified enzyme retained high enantioselectivity and was ca. 80 times more active than the native enzyme in anhydrous hexane. Likewise, the activity of horseradish peroxidase (HRP) lyophilized from 8 M urea was ca. 56 times and 350 times higher in 97% acetone and water-saturated hexane, respectively, than the activity of HRP lyophilized from aqueous buffer. Compared with the native enzyme, the partially unfolded enzyme may have a more pliant and less rigid conformation in organic solvents, thus enabling it to retain higher catalytic activity. However, no substantial activation was observed for alpha-chymotrypsin lyophilized from urea solutions in which the enzyme retained some activity, illustrating that the activation effect is not completely general.  (+info)

Heptanes are a group of hydrocarbons that are composed of straight-chain or branched arrangements of six carbon atoms and are commonly found in gasoline. They are colorless liquids at room temperature with a characteristic odor. In a medical context, exposure to heptanes can occur through inhalation, skin contact, or ingestion, and can cause symptoms such as headache, dizziness, nausea, and irritation of the eyes, nose, and throat. Chronic exposure has been linked to more serious health effects, including neurological damage and cancer. Proper handling and use of heptanes, as well as adequate ventilation, are important to minimize exposure and potential health risks.

A plant extract is a preparation containing chemical constituents that have been extracted from a plant using a solvent. The resulting extract may contain a single compound or a mixture of several compounds, depending on the extraction process and the specific plant material used. These extracts are often used in various industries including pharmaceuticals, nutraceuticals, cosmetics, and food and beverage, due to their potential therapeutic or beneficial properties. The composition of plant extracts can vary widely, and it is important to ensure their quality, safety, and efficacy before use in any application.

Ardisia is a genus of evergreen trees and shrubs in the primrose family (Primulaceae) that are native to tropical and subtropical regions around the world. Some species of Ardisia have medicinal uses, but there is no single medical definition for 'Ardisia' as it is not a term used to describe a specific medical condition or treatment.

In traditional medicine, some Ardisia species have been used to treat various health issues such as digestive disorders, skin conditions, and respiratory infections. However, it is important to note that the use of Ardisia for medicinal purposes has not been extensively studied in clinical trials, and its safety and efficacy are not well-established. Therefore, it is recommended to consult with a healthcare provider before using any Ardisia species or products derived from them for medicinal purposes.

"Piper" is not a medical term. It is a genus of plants in the family Piperaceae, which includes black pepper and many other species. In some cases, "piper" may refer to piperazine, a class of medications used to treat various conditions such as intestinal worm infections and symptoms of mental disorders. However, it's not a commonly used medical term.

"Calophyllum" is a genus of plants that belongs to the family Calophyllaceae. These evergreen trees and shrubs are native to tropical regions of the world, particularly in Southeast Asia, Africa, and the Pacific Islands. The name "Calophyllum" comes from the Greek words "kalos," meaning beautiful, and "phyllon," meaning leaf, which refers to the attractive leaves of these plants.

Many species of Calophyllum have medicinal properties. For example, the bark, leaves, and seeds of Calophyllum inophyllum, also known as Alexandrian laurel or Indian laurel, have been used in traditional medicine to treat a variety of conditions, including skin diseases, rheumatism, and diarrhea. The oil extracted from the seeds of this plant, called "tamanu oil," is believed to have anti-inflammatory, antibacterial, and antioxidant properties and is used in cosmetics and skincare products.

However, it's important to note that while some species of Calophyllum have medicinal uses, they should not be used as a substitute for professional medical advice, diagnosis, or treatment. It's always recommended to consult with a healthcare provider before using any natural remedies or supplements.

Solvents, in a medical context, are substances that are capable of dissolving or dispersing other materials, often used in the preparation of medications and solutions. They are commonly organic chemicals that can liquefy various substances, making it possible to administer them in different forms, such as oral solutions, topical creams, or injectable drugs.

However, it is essential to recognize that solvents may pose health risks if mishandled or misused, particularly when they contain volatile organic compounds (VOCs). Prolonged exposure to these VOCs can lead to adverse health effects, including respiratory issues, neurological damage, and even cancer. Therefore, it is crucial to handle solvents with care and follow safety guidelines to minimize potential health hazards.

Polyanhydrides are a type of biodegradable polymer that contain repeating units of anhydride groups in their molecular structure. These polymers have been studied for various medical applications, particularly as drug delivery systems, due to their ability to degrade into non-toxic components over time.

When exposed to body fluids or water, polyanhydrides undergo hydrolysis, breaking down into their constituent monomers and releasing the drug that was encapsulated within them. This property makes polyanhydrides useful for controlled release applications, as they can be designed to degrade at specific rates, allowing for the sustained delivery of drugs over a period of time.

Polyanhydrides have been used in a variety of medical devices and drug delivery systems, including implantable drug-delivery vehicles, tissue engineering scaffolds, and surgical sealants. They are also being investigated as potential materials for use in regenerative medicine and other biomedical applications.

'Citrus aurantiifolia' is the scientific name for a species of citrus fruit known as Key lime or Mexican lime. It is a small, thorny evergreen tree that typically grows to around 5 meters in height. The fruit of this tree is small and round, with a green, thin, and wrinkled skin that turns yellow when ripe. The interior of the fruit is juicy, tart, and aromatic, making it popular for use in various culinary applications, particularly in the preparation of Key lime pie.

The Key lime is native to Southeast Asia but was brought to the Americas by Spanish explorers in the 16th century. It is now widely cultivated in tropical and subtropical regions around the world, including Florida and Mexico, where it is a significant commercial crop. The Key lime tree is also valued for its attractive flowers and decorative foliage.

I apologize, but "Cleome" is not a medical term. It is the name of a genus of plants commonly known as spider flowers or cleomes. These plants are not associated with any specific medical conditions or definitions. If you have any questions related to medical terminology or health concerns, I would be happy to try and help answer them for you.

Alkanes are a group of saturated hydrocarbons, which are characterized by the presence of single bonds between carbon atoms in their molecular structure. The general formula for alkanes is CnH2n+2, where n represents the number of carbon atoms in the molecule.

The simplest and shortest alkane is methane (CH4), which contains one carbon atom and four hydrogen atoms. As the number of carbon atoms increases, the length and complexity of the alkane chain also increase. For example, ethane (C2H6) contains two carbon atoms and six hydrogen atoms, while propane (C3H8) contains three carbon atoms and eight hydrogen atoms.

Alkanes are important components of fossil fuels such as natural gas, crude oil, and coal. They are also used as starting materials in the production of various chemicals and materials, including plastics, fertilizers, and pharmaceuticals. In the medical field, alkanes may be used as anesthetics or as solvents for various medical applications.

Propolis is a resinous substance that honeybees collect from tree buds, sap flows, or other botanical sources. They use it to seal gaps and holes in their hives as a protective barrier against external threats such as intruders (like other insects) and harsh weather conditions. Propolis has been found to have various chemical compositions depending on the plant sources, but it primarily consists of flavonoids, phenolic acids, and esters, which contribute to its biological activities. It has been used in traditional medicine for centuries due to its potential health benefits, including antimicrobial, anti-inflammatory, antioxidant, and wound-healing properties; however, more scientific research is needed to confirm these effects and establish safe and effective therapeutic dosages.

Gas Chromatography-Mass Spectrometry (GC-MS) is a powerful analytical technique that combines the separating power of gas chromatography with the identification capabilities of mass spectrometry. This method is used to separate, identify, and quantify different components in complex mixtures.

In GC-MS, the mixture is first vaporized and carried through a long, narrow column by an inert gas (carrier gas). The various components in the mixture interact differently with the stationary phase inside the column, leading to their separation based on their partition coefficients between the mobile and stationary phases. As each component elutes from the column, it is then introduced into the mass spectrometer for analysis.

The mass spectrometer ionizes the sample, breaks it down into smaller fragments, and measures the mass-to-charge ratio of these fragments. This information is used to generate a mass spectrum, which serves as a unique "fingerprint" for each compound. By comparing the generated mass spectra with reference libraries or known standards, analysts can identify and quantify the components present in the original mixture.

GC-MS has wide applications in various fields such as forensics, environmental analysis, drug testing, and research laboratories due to its high sensitivity, specificity, and ability to analyze volatile and semi-volatile compounds.

Bicyclic compounds are organic molecules that contain two rings in their structure, with at least two common atoms shared between the rings. These compounds can be found in various natural and synthetic substances, including some medications and bioactive molecules. The unique structure of bicyclic compounds can influence their chemical and physical properties, which may impact their biological activity or reactivity.

Croton oil is a highly toxic, irritant, and vesicant liquid that is derived from the seeds of the croton tiglium plant. It is a type of unsaturated fatty acid known as an octadecatrienoic acid, and it contains a mixture of various chemical compounds including crotonic acid, diglycerides, and phorbol esters.

Croton oil is commonly used in laboratory research as a pharmacological tool to study the mechanisms of inflammation, pain, and skin irritation. It can also be used as a veterinary medicine to treat certain types of intestinal parasites in animals. However, due to its high toxicity and potential for causing severe burns and blisters on the skin, it is not used in human medicine.

It's important to note that croton oil should only be handled by trained professionals in a controlled laboratory setting, as improper use or exposure can result in serious injury or death.

"Psidium" is a scientific name for a genus of plants that include several species of tropical trees and shrubs, the most well-known of which is "Psidium guajava," or the common guava. These plants are native to Central and South America and are now grown in many tropical and subtropical regions around the world.

The fruits of these plants are also commonly referred to as "guavas" and are popular for their sweet, tangy flavor and high nutritional content. They are rich in vitamin C, dietary fiber, and antioxidants, making them a valuable addition to a healthy diet.

In medical or scientific contexts, the term "Psidium" may be used to refer specifically to the genus of plants or more broadly to any plant or fruit within that genus.

Phytotherapy is the use of extracts of natural origin, especially plants or plant parts, for therapeutic purposes. It is also known as herbal medicine and is a traditional practice in many cultures. The active compounds in these plant extracts are believed to have various medicinal properties, such as anti-inflammatory, analgesic, or sedative effects. Practitioners of phytotherapy may use the whole plant, dried parts, or concentrated extracts to prepare teas, capsules, tinctures, or ointments for therapeutic use. It is important to note that the effectiveness and safety of phytotherapy are not always supported by scientific evidence, and it should be used with caution and preferably under the guidance of a healthcare professional.

I am not a medical expert, but I can provide some information that may be helpful. "Picrates" is not a term commonly used in medical definitions. Instead, it is a term used in chemistry to refer to salts of picric acid (2,4,6-trinitrophenol), which was once used as a yellow dye and explosive.

Picric acid has been used historically in some medical applications, such as a component in certain topical antiseptics and in histological staining procedures. However, its use in modern medicine is quite limited due to its high sensitivity to impact, heat, and friction, which makes it potentially dangerous to handle.

Therefore, it's important to note that "picrates" is not a medical term per se but rather a chemical one, and any medical application of picric acid or its salts would be highly specialized and unlikely to be encountered in most healthcare settings.

Adenosine A3 receptor agonists are a type of pharmaceutical compound that bind to and activate the adenosine A3 receptor, which is a type of G-protein coupled receptor found in various tissues throughout the body. Activation of the A3 receptor has been shown to have anti-inflammatory and analgesic effects, making it a target for the development of drugs to treat conditions such as rheumatoid arthritis, inflammatory bowel disease, and chronic pain. Examples of adenosine A3 receptor agonists include IB-MECA, Cl-IB-MECA, and MRS1523.

Chemical fractionation is a process used in analytical chemistry to separate and isolate individual components or fractions from a mixture based on their chemical properties. This technique typically involves the use of various chemical reactions, such as precipitation, extraction, or chromatography, to selectively interact with specific components in the mixture and purify them.

In the context of medical research or clinical analysis, chemical fractionation may be used to isolate and identify individual compounds in a complex biological sample, such as blood, urine, or tissue. For example, fractionating a urine sample might involve separating out various metabolites, proteins, or other molecules based on their solubility, charge, or other chemical properties, allowing researchers to study the individual components and their roles in health and disease.

It's worth noting that while chemical fractionation can be a powerful tool for analyzing complex mixtures, it can also be time-consuming and technically challenging, requiring specialized equipment and expertise to perform accurately and reliably.

I'm sorry for any confusion, but "Plant Bark" is not a term with a specific medical definition. In general, the bark refers to the outermost covering of a tree or other plant, which serves as protection and provides a barrier against external threats. It is composed of layers including the inner bark (phloem), which transports nutrients throughout the plant, and the outer bark (periderm), which is made up of dead cells that form a protective layer.

While some plants or plant parts do have medicinal properties and are used in various forms of traditional or alternative medicine, "Plant Bark" by itself does not have any specific medical connotations. If you're referring to a specific type of plant bark with potential medicinal uses, please provide more details so I can give a more accurate response.

I believe there may be a slight misunderstanding in your question. "Plant leaves" are not a medical term, but rather a general biological term referring to a specific organ found in plants.

Leaves are organs that are typically flat and broad, and they are the primary site of photosynthesis in most plants. They are usually green due to the presence of chlorophyll, which is essential for capturing sunlight and converting it into chemical energy through photosynthesis.

While leaves do not have a direct medical definition, understanding their structure and function can be important in various medical fields, such as pharmacognosy (the study of medicinal plants) or environmental health. For example, certain plant leaves may contain bioactive compounds that have therapeutic potential, while others may produce allergens or toxins that can impact human health.

I am not aware of a widely recognized medical definition for the term "Salacia." It is possible that you may be referring to a plant species called Salacia reticulata, which has been used in traditional Ayurvedic medicine. The dried root bark of this plant is used to make various medicinal preparations. Some proponents of alternative medicine claim that it has potential health benefits such as reducing blood sugar levels, improving insulin sensitivity, and aiding in weight loss. However, more scientific research is needed to confirm these claims and establish recommended dosages and potential side effects.

A rhizome is not typically used as a medical term, but it is a term borrowed from botany that has been adopted in some areas of medicine, particularly in psychiatry and psychotherapy.

In its original botanical sense, a rhizome is a horizontal stem of a plant that grows underground, often sending out roots and shoots from its nodes. This growth pattern is contrasted with that of a root system, which grows downward, and a stem system, which grows upward.

In psychiatry and psychotherapy, the term "rhizome" has been used as a metaphor to describe a non-hierarchical and decentralized approach to understanding mental processes and subjectivity. The rhizome model emphasizes the complexity, multiplicity, and interconnectedness of these processes, and rejects simplistic or reductionist explanations that focus on a single cause or origin. Instead, it encourages a more holistic and dynamic view of mental life, one that is open to multiple perspectives and interpretations.

It's important to note that the use of the term "rhizome" in this context is metaphorical and not medical in the strict sense. It is a way of thinking about mental processes and subjectivity that has been influenced by poststructuralist and feminist theories, among others.

The term "Croton" is most commonly used to refer to a genus of flowering plants in the spurge family (Euphorbiaceae), which includes over 700 species. These plants are native to tropical and subtropical regions around the world, with many having colorful and distinctive leaves or flowers.

However, "Croton" is not a medical term and does not have a specific definition in the context of medicine. If you have any questions about a medical condition or treatment that involves the use of the term "Croton," it would be best to consult with a healthcare professional for clarification.

Adenosine A3 receptor antagonists are a class of pharmaceutical compounds that block the action of adenosine at the A3 receptor. Adenosine is a naturally occurring purine nucleoside that acts as a neurotransmitter and modulator of various physiological processes, including cardiovascular function, immune response, and neuromodulation.

The A3 receptor is one of four subtypes of adenosine receptors (A1, A2A, A2B, and A3) that are widely distributed throughout the body. The activation of A3 receptors has been implicated in a variety of pathological conditions, including inflammation, pain, ischemia-reperfusion injury, and cancer.

Adenosine A3 receptor antagonists have been investigated as potential therapeutic agents for various diseases, such as rheumatoid arthritis, chronic pain, ischemic heart disease, and cancer. These compounds work by preventing the binding of adenosine to its receptor, thereby blocking its downstream signaling pathways.

Some examples of Adenosine A3 receptor antagonists include:

* MRS1523
* MRE-2029F20
* LUF5834
* VUF5574
* OT-7962

It is important to note that while Adenosine A3 receptor antagonists have shown promise in preclinical studies, their clinical efficacy and safety profile are still being evaluated in ongoing research.

... hexane. The term hexanes refers to a mixture, composed largely (>60%) of n-hexane, with varying amounts of the isomeric ... The current n-hexane PEL in the US is 500 ppm (1,800 mg/m3 (0.79 gr/cu ft)). Hexane and other volatile hydrocarbons (petroleum ... Hexane (/ˈhɛkseɪn/) or n-hexane is an organic compound, a straight-chain alkane with six carbon atoms and has the molecular ... These "hexanes" mixtures are cheaper than pure hexane and are often used in large-scale operations not requiring a single ...
hexane-1,6-diol (CHEBI:43078) has parent hydride hexane (CHEBI:29021). hexane-2,5-diol (CHEBI:84894) has parent hydride hexane ... hexane (CHEBI:29021) has role non-polar solvent (CHEBI:48355) hexane (CHEBI:29021) is a alkane (CHEBI:18310) hexane (CHEBI: ... hexanal (CHEBI:88528) has parent hydride hexane (CHEBI:29021). hexane-1,6-diamine (CHEBI:39618) has parent hydride hexane ( ... 2-hexanamine (CHEBI:195543) has parent hydride hexane (CHEBI:29021). 3-hexanone (CHEBI:89891) has parent hydride hexane (CHEBI: ...
Inhaling n-hexane causes nerve damage and paralysis of the arms and legs. Some people abuse products containing n-hexane by ... n-Hexane is mixed with solvents for a number of uses. ... n-Hexane is a chemical made from crude oil. Pure n-hexane is a ... How might I be exposed to n-hexane?. *You are most likely to be exposed to n-hexane by breathing in air contaminated with it. ... Pure n-hexane is used in laboratories. Most of the n-hexane used in industry is mixed with similar chemicals called solvents. ...
Other names: Perfluoro-n-hexane; Perfluorohexane; PP 1 (Fluorocarbon); Tetradecafluorohexane; n-Tetradecafluorohexane; ... Fluorinert FC72; Flutec PP1; n-Perfluorohexane; Perfluoro-compound FC-72; AF 0150; Hexane, 1,1,1,2,2,3,3,4,4,5,5,6,6,6- ...
The National Institute of Standards and Technology (NIST) uses its best efforts to deliver a high quality copy of the Database and to verify that the data contained therein have been selected on the basis of sound scientific judgment. However, NIST makes no warranties to that effect, and NIST shall not be liable for any damage that may result from errors or omissions in the Database ...
... NSC249259 3313-85-7 6-bicyclo[3.1.0]hexylmethanol ... Bicyclo[3.1.0]hexane-6-methanol Molecular Formula: C7H12O ...
Significance and Use 3.1 This test method measures the amount of hexane-soluble lubricant present in all types of leather. ... Standard Test Method for Hexane Extraction of Leather. Standard Test Method for Hexane Extraction of Leather D3495-10R15 ASTM, ... D3495-10R15,en-US Standard Test Method for Hexane Extraction of Leather Standard D3495 Standard Test Method for Hexane ... 1.1 This test method covers the quantitative extraction of all types of leather with hexane. This test method does not apply to ...
Actual lot of analysis on label Shop Hexanes (Certified ACS), Fisher Chemical™  at Fishersci.com ... n-hexane, esani, skellysolve b, gettysolve-b, hexyl hydride, hexan, dipropyl, heksan, hexanen, hexanes. ... n-hexane, esani, skellysolve b, gettysolve-b, hexyl hydride, hexan, dipropyl, heksan, hexanen, hexanes. ...
However, the revised IDLH for n-hexane is 1,100 ppm based strictly on safety considerations (i.e., being 10% of the lower ... 3. Patty FA, Yant WP [1929]. Odor intensity and symptoms produced by commercial propane, butane, pentane, hexane, and heptane ...
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The hexane thus recovered is reused for extraction. The low boiling point of hexane (67°C / 152°F) and the high solubility of ... Hexane solvent oil extraction - Definition, Glossary, Details - Oilgae. Solvent Extraction is a process which involves ... In a nutshell, the extraction process consists of treating the raw material with hexane and recovering the oil by distillation ... Evaporation and condensation from the distillation of miscella recovers the hexane absorbed in the material. ...
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GFS Chemicals is a leading supplier of Hexanes, Reagent, CAS 110-54-3, SKU 41757. GFS Chemicals has the expertise to handle all ...
... the global n-hexane market size reached US$ 2,461 Million in 2021 and is expected to reach US$ 3,039 Million by 2027, ... N-Hexane Industry Segmentation:. IMARC Group provides an analysis of the key trends in each segment of the global N-hexane ... Edible Oil Extraction is dominating the N-Hexane The report has provided a detailed breakup and analysis of the N-hexane market ... N-Hexane Market Trends/Drivers:. Significant growth in the pharmaceutical industry. The widespread product adoption as a ...
Separate groups of eight rats were exposed to 100 ppm n-hexane, 200 ppm MEK, 100 ppm n-hexane plus 200 ppm MEK, or fresh air in ... This study was intended to determine whether or not methyl ethyl ketone (MEK) enhances the neurotoxicity of n-hexane at low ... These results suggest that MEK might enhance the neurotoxicity of n-hexane at a low concentration, and mixed exposures to n- ... Exposure of 100 ppm n-hexane did not significantly decrease the functions of the peripheral nerve throughout the experiment. ...
... Catalog No. 31481 ... MA Fractionation Check Mix, 25 ug/mL, Hexane, 1 mL/ampul. .RCPDP_ProductPrice{padding-bottom:2.5rem}.RCPDP_ProductPrice span{ ... MA Fractionation Check Mix, 25 ug/mL, Hexane, 1 mL/ampul. .product-information_section{margin:0 auto;max-width:1440px!important ...
EP-2079690-B1 chemical patent summary.
5 mg/mL in hexane. Description Density. 0.6665 g/mL. Storage. 2-8°C. Concentration. 5 mg/mL in hexane. Solvent. Toluene. ... CdSe/CdS core-shell type quantum rods fluorescence λem 590 nm, 5 mg/mL in hexane. *Price: ... CdSe/CdS core-shell type quantum rods fluorescence λem 590 nm, 5 mg/mL in hexane ...
Hi! Can I get a quote for a GreenScreen Assessment of 3-N,4-N-Bis(4-chlorophenyl)hexane-3,4-diimine;dibromonickel [616895-43-3 ... Is anyone else interested in sharing the cost of a GreenScreen assessment of 3-N,4-N-Bis(4-chlorophenyl)hexane-3,4-diimine; ... Share 3-N,4-N-Bis(4-chlorophenyl)hexane-3,4-diimine;dibromonickel. × ... Profile for "3-N,4-N-Bis(4-chlorophenyl)hexane-3,4-diimine;dibromonickel" on Pharos: https://pharosproject.net/chemicals/ ...
Hexane Community Game Servers Features Server Configuration General User Configuration Topic. Replies. Views. Activity. ...
HEXANE,4-METHYL-3-METHYLENE-1-(ISOPROPYL)-,BICYCLO[3.1.0]HEXANE,6,6-DICHLORO-1-METHYL- ... Synonyms: Bicyclo(3.1.0)hexane-1-carbonitrile, 1-Cyanobicyclo[3.1.0]hexane, AC1L3JIH, CTK1C4058, bicyclo[3.1.0]hexane-5- ... hexane, 6-propan-2-ylidenebicyclo[3.1.0]hexane, 6-(1-Methylethylidene)bicyclo[3.1.0]hexane # Molecular Formula: C9H14. ... BICYCLO[3.1.0]HEXANE,6-BROMO- (3 suppliers). IUPAC Name: 6-bromobicyclo[3.1.0]hexane , CAS Registry Number: 413585-18-9. ...
Hexane-1,6-diyl)bis(4-methyl-N-(oxiran-2-ylmethyl)benzenesulfonamide): Synthesis via cyclodextrin mediated N-alkylation in ... Two-fold N-alkylation of β-CD-complexed N,N-(hexane-1,6-diyl)bis(4-methylbenzenesulfonamide) (3β) with 4α in aqueous solution ... An alternative route for the synthesis of N,N-(hexane-1,6-diyl)bis(4-methyl-N-(oxiran-2-ylmethyl)benzenesulfonamide) (6) via N ... N,N-(Hexane-1,6-diyl)bis(4-methyl-N-(oxiran-2-ylmethyl)benzenesulfonamide): Synthesis via cyclodextrin mediated N-alkylation ...
After 7.50 mL of hexane, C6H14, is pipetted into the beaker, the combined mass of the beaker and the heaxane sample is ... Explain what is the measured density of hexane. Assignment Help Chemistry Reference no: EM13266834 The mass of a beaker is ... 7.839g. After 7.50 mL of hexane, C6H14, is pipetted into the beaker, the combined mass of the beaker and the heaxane sample is ...
Strain-Release [2π + 2σ] Cycloadditions for the Synthesis of Bicyclo[2.1.1]hexanes Initiated by Ener… ... Study on the Pharmacokinetics of Bromine Hexane Hydrochloride Tablets in Healthy Adults ...
Hexane gas sensor - LEL detector with flameproof, ATEX, SIL 2, Zone 1. Read more ...
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3,3-Diphenyl-6-(p-toluenesulfonyl)-6-aza-3-silabicyclo[3.1.0]hexane ... 3,3-Diphenyl-6-(p-toluenesulfonyl)-6-aza-3-silabicyclo[3.1.0]hexane ...
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  • co-exposure to toluene decreases the neurotoxic effects of n-hexane. (who.int)
  • The air concentrations of n-hexane and those of acetone, toluene, and other organic solvents were monitored with charcoal tubes. (bmj.com)
  • To assess the cytogenetic damage related to occupational exposure to airborne chemicals during shoe-making and the processes in pathology and anatomy laboratories, the micronuclei (MN) count per 3000 cells was measured in buccal smears from shoe-workers (group I, n = 22) exposed to mainly n-hexane, toluene and methyl ethyl ketone (MEK) and from anatomy and pathology staff (group II, n = 28) exposed to formaldehyde (FA). (hacettepe.edu.tr)
  • The mean time-weighted average (TWA) concentrations of n-hexane, toluene and MEK in 10 small shoe workshops were 58.07 p. p. m., 26.62 p. p. m. and 11.39 p. p. m., respectively. (hacettepe.edu.tr)
  • Levels of 2,5-hexadione (2,5-HD) and hippuric acid (HA), metabolic markers of n-hexane and toluene exposure, respectively, were significantly higher in the urine of workers in group I than in control subjects (p (hacettepe.edu.tr)
  • Overall, the results suggest that occupational exposure to organic solvents, mainly n-hexane, toluene, MEK and FA, may cause cytogenetic damage in buccal cells and that use of exfoliated buccal cells seems to be appropriate to measure exposure to organic solvents. (hacettepe.edu.tr)
  • Each sample was also speciated for 14 identified compounds including n-hexane, benzene, toluene, and the xylenes. (cdc.gov)
  • Linear Relationships Between Total Hydrocarbons and Benzene, Toluene, Ethylbenzene, Xylene, and n-Hexane during the Deepwater Horizon Response and Clean-up. (nih.gov)
  • The US National Institute for Occupational Safety and Health (NIOSH) has set a recommended exposure limit (REL) for hexane isomers (not n-hexane) of 100 ppm (350 mg/m3 (0.15 gr/cu ft)) over an 8-hour workday. (wikipedia.org)
  • Hexane " or " hexanes " is a commercial and industrial product consisting of a mixture of hydrocarbons with six carbon atoms and includes n- hexane and its isomers 2-methylpentane and 3-methylpentane as well as small amounts of other hydrocarbons (Brugnone et al.1991). (cdc.gov)
  • Is cyclohexane and hexane isomers? (yourquickinformation.com)
  • Hexane and cyclohexane are not isomers. (yourquickinformation.com)
  • The five isomers possible for hexane are n- hexane, 2- methyl pentane, 3- methyl pentane, 2, 3-dimethylbutane and 2, 2- dimethylbutane. (yourquickinformation.com)
  • It is a colorless liquid, odorless when pure, and with boiling points approximately 69 °C (156 °F). It is widely used as a cheap, relatively safe, largely unreactive, and easily evaporated non-polar solvent, and modern gasoline blends contain about 3% hexane. (wikipedia.org)
  • These "hexanes" mixtures are cheaper than pure hexane and are often used in large-scale operations not requiring a single isomer (e.g., as cleaning solvent or for chromatography). (wikipedia.org)
  • Hexanes are commonly used in chromatography as a non-polar solvent. (wikipedia.org)
  • Higher alkanes present as impurities in hexanes have similar retention times as the solvent, meaning that fractions containing hexane will also contain these impurities. (wikipedia.org)
  • n-Hexane is also used as a solvent, a cleaning agent, in the rubber industry, and in the manufacture of pharmaceuticals. (who.int)
  • Hexane is a petroleum-based solvent widely used industrially, especially in the food industry for the extraction of oils, vegetable proteins and natural ingredients. (foodnavigator.com)
  • Authorising the plant-based hexane alternative marks the first time since Directive 2009/32/CE was issued that a new liquid solvent is entering into the regulation. (foodnavigator.com)
  • The relative excretion of HD increased as the exposure to n-hexane increased, although it seemed that HD accumulated progressively in the body at the highest n-hexane concentrations and at higher total solvent concentrations. (bmj.com)
  • So it will dissolve in the non-polar solvent hexane. (swelec.com)
  • Solubility of Naphthalene in Various Solvents* solvent mole percent naphthalene Benzene 24.1 Carbon tetrachloride 20.5 Hexane 9.0 Methyl alcohol 1.8 Water 0.0004 *At 20 degrees Celsius. (swelec.com)
  • The ionic and very hydrophilic sodium chloride, for example, is not at all soluble in hexane solvent, while the hydrophobic biphenyl is very soluble in hexane. (swelec.com)
  • The procedure involves a combination of high-temperature mechanical pressing and solvent extract, usually using hexane. (naturalnews.com)
  • Hexane has considerable vapor pressure at room temperature: Like most alkanes, hexane characteristically exhibits low reactivity and are suitable solvents for reactive compounds. (wikipedia.org)
  • n -Hexane is mixed with solvents for a number of uses. (cdc.gov)
  • Most of the n -hexane used in industry is mixed with similar chemicals called solvents. (cdc.gov)
  • The major use for solvents containing n -hexane is to extract vegetable oils from crops such as soybeans. (cdc.gov)
  • These findings are further supported by observations in humans, which draw upon several reports of peripheral neuropathy in workers exposed to n-hexane and in abusers of glues or solvents containing this chemical. (who.int)
  • Grand Rounds: Could Occupational Exposure to n-Hexane and Other Solvents Precipitate Visual Failure in Leber Hereditary Optic Neuropathy? (nih.gov)
  • The solubility of naphthalene has been determined at 25° in the six binary mixed solvents from among carbon tetrachloride, cyclohexane, n-hexane, and n-hexadecane. (swelec.com)
  • Terminalia belirica (Combretaceae) dried fruits was comparatively extracted with solvents of different polarities (hexane, chloroform, methanol and aqueous), screened against Trypansoma evansi at different concentrations (250-1000 µg/ml) on Vero cell line grown in Dulbecco's Modified Eagle Medium (DMEM) supplemented with fetal calf serum (FCS) 40% and incubated at appropriate conditions. (ispub.com)
  • Silica gel-G for thin layer chromatography (TLC), solvents (hexane, chloroform, methanol and aqueous) for extraction of plant materials and development /analysis of TLC plates, vanillin for spray and iodine for detection of bioactive constituents These were purchased from E. Merck , India. (ispub.com)
  • It is soluble in cyclohexane (like benzene), but not as soluble in n-hexane. (swelec.com)
  • Hexane (/ˈhɛkseɪn/) or n-hexane is an organic compound, a straight-chain alkane with six carbon atoms and has the molecular formula C6H14. (wikipedia.org)
  • Hexane is an alkane of six carbon atoms, with the chemical formula C6H14. (openpr.com)
  • These molecules differ only in their length, being members of the n‐alkane series [CH3(CH2)n−2CH3] where n=4 for butane and n=6 for hexane. (umsystem.edu)
  • The key difference between hexane and cyclohexane is that hexane is an acyclic alkane while cyclohexane is a cyclic alkane with a ring structure. (yourquickinformation.com)
  • Hence, hexane is an alkane and is unbranched. (yourquickinformation.com)
  • We have studied the solvation statics and dynamics of coumarin 153 and 102 dyes in hexane - methanol mixtures. (tau.ac.il)
  • We analyzed the statics and dynamics of the solvation of coumarin dyes in a hexane - methanol mixture using a model of two distinct solvates. (tau.ac.il)
  • Molotsky, T & Huppert, D 2003, ' Site specific solvation statics and dynamics of coumarin dyes in hexane-methanol mixture ', Journal of Physical Chemistry A , vol. 107, no. 16, pp. (tau.ac.il)
  • Order of trypanocidal activity was methanol, aqueous, chloroform and hexane. (ispub.com)
  • Various types of commercial grades of n- hexane are available, and the constituents besides n- hexane are usually an intentional part of the process for preparing these commercial mixtures. (cdc.gov)
  • Hexane and other volatile hydrocarbons (petroleum ether) present an aspiration risk. (wikipedia.org)
  • Anticancer properties of hexane and chloroform extracts of the horsetail fern plant and their mechanisms involved in the anticancer activity on human hepatocarcinoma (HuH-7) cells were examined. (nih.gov)
  • Other parameters such as oxidative stress and apoptosis in pretreated hexane and chloroform extracts of the horsetail fern plant were examined in HuH-7 cells. (nih.gov)
  • The observation showed that hexane and chloroform extract of the horsetail fern plant exhibited cytotoxicity against HuH-7 cells. (nih.gov)
  • The value of IC 50 -24 h of hexane and chloroform extract of the horsetail fern plant was determined as 199.0 μ g/ml and 161.90 0 μ g/ml for HuH-7 cells, respectively, and on the basis of IC 50 value, three acute concentrations, viz. (nih.gov)
  • The lower dose of extracts hexane and chloroform extract of the horsetail fern plant did not show significant toxicity. (nih.gov)
  • The term hexanes refers to a mixture, composed largely (>60%) of n-hexane, with varying amounts of the isomeric compounds 2-methylpentane and 3-methylpentane, and possibly, smaller amounts of nonisomeric C5, C6, and C7 (cyclo)alkanes. (wikipedia.org)
  • Methyloxolane now joins other approved hexane alternatives on the market, including superficial CO₂ and hot ethanal extraction. (foodnavigator.com)
  • Hexane, a highly flammable and costly gas, is used in most oilseed crush operations to achieve maximum oil extraction efficiency. (opgal.com)
  • The hexane free extraction of Frangipani renders a clear and profound concentrated aroma. (lgbotanicals.com)
  • In industry, hexanes are used in the formulation of glues for shoes, leather products, and roofing. (wikipedia.org)
  • Certain kinds of special glues used in the roofing and shoe and leather industries also contain n -hexane. (cdc.gov)
  • Several consumer products contain n -hexane, such as gasoline, quick-drying glues used in various hobbies, and rubber cement. (cdc.gov)
  • Keep products containing n -hexane (quick-drying glues and cements) out of the reach of children. (cdc.gov)
  • Hexane is also an ingredient of special glues that are used in the roofing, shoe, and leather industries. (openpr.com)
  • Chronic occupational exposure to elevated levels of n-hexane has been demonstrated to be associated with peripheral neuropathy in auto mechanics in the US, and neurotoxicity in workers in printing presses, and shoe and furniture factories in Asia, Europe, and North America. (wikipedia.org)
  • Exposure can occur at home if you use products containing n -hexane without proper ventilation. (cdc.gov)
  • The only people known to have been affected by exposure to n -hexane used it at work. (cdc.gov)
  • Since most exposure occurs at work, children aren't likely to be exposed to levels of n -hexane that cause problems. (cdc.gov)
  • How can families reduce the risk of exposure to n -hexane? (cdc.gov)
  • A review of investigations in experimental animals and in vitro test systems concentrates on testicular lesions and neurotoxicity as the principal effects of repeated exposure to n-hexane. (who.int)
  • While concluding that n-hexane is not likely to present a hazard to either the general population or the environment, the report stresses the need for precautions in the occupational setting, including the use of suitably designed work processes and engineering controls for reducing atmospheric levels below the recommended occupational exposure limits. (who.int)
  • "Our goal is now to support the producers of food oils and natural ingredients to progressively abandon the use of hexane in favour of methyloxolane and thus reduce the exposure of the general population to this toxic product," ​said Jacques. (foodnavigator.com)
  • 2,5-Hexanedione excretion after occupational exposure to n-hexane. (bmj.com)
  • RESULTS: Correlations between measurements of THC and each of the BTEX-H chemicals (n = 120 for each of BTEX, 36 for n-hexane) differed substantially by area of the Gulf of Mexico and by time period that reflected different oil-spill related exposure opportunities. (nih.gov)
  • n- Hexane is flammable and may be ignited by heat, sparks, and flames. (cdc.gov)
  • In preparative chromatography, concentration of a large volume of hexanes can result in a sample that is appreciably contaminated by alkanes. (wikipedia.org)
  • The tubes were analyzed for hexane equivalent concentrations by gas chromatography in our laboratories and, as a quality control, 48 paired samples were analyzed at a commercial lab. (cdc.gov)
  • Like gasoline, hexane is highly volatile and is an explosion risk. (wikipedia.org)
  • Since it is in gasoline, nearly everyone is exposed to very small amounts of n -hexane in the air. (cdc.gov)
  • Due to the cyclic arrangement in its molecular structure, cyclohexane possesses a lesser number of hydrogen atoms compared to hexane. (yourquickinformation.com)
  • The molecular formula of hexane, which consists of 6 carbon atoms and 14 hydrogen atoms, is C 6 H 14. (yourquickinformation.com)
  • n- Hexane is a very volatile aliphatic hydrocarbon. (cdc.gov)
  • Hexanes are chiefly obtained by refining crude oil. (wikipedia.org)
  • n -Hexane is a chemical made from crude oil. (cdc.gov)
  • Evaluates the risks to human health and the environment posed by n-hexane, a chemical isolated from natural gas and crude oil and used in food processing to extract vegetable oil from beans, nuts, and seeds. (who.int)
  • Hexane is an organic compound made of carbon and hydrogen that is most commonly isolated as a byproduct of petroleum and crude oil refinement. (openpr.com)
  • The correlation between excretion of HD and the n-hexane concentrations in the workroom air was evaluated. (bmj.com)
  • The average hexane equivalent concentration over the 12 hours at a workbench in the space was 75.5 mg/m3, 31% of which was loluene. (cdc.gov)
  • Books for Grades 5-12 Online Courses For each compound, would you expect greater solubility in water or hexane (C6H14)? (swelec.com)
  • The molecular formula of cyclohexane is C6H12 while of hexane, it is C6H14. (yourquickinformation.com)
  • The 1981 Louisville sewer explosions, which destroyed over 13 mi (21 km) of sewer lines and streets in Kentucky, were caused by ignition of hexane vapors which had been illegally discharged from a soybean processing plant owned by Ralston-Purina. (wikipedia.org)
  • A typical laboratory use of hexanes is to extract oil and grease contaminants from water and soil for analysis. (wikipedia.org)
  • Since hexane cannot be easily deprotonated, it is used in the laboratory for reactions that involve very strong bases, such as the preparation of organolithiums. (wikipedia.org)
  • In laboratory studies, animals exposed to high levels of n -hexane in air had signs of nerve damage. (cdc.gov)
  • Laboratory grade n- hexane contains approximately 99% n- hexane. (cdc.gov)
  • Yet as the European Chemicals Agency (ECHA) has reclassified hexane as a proven human neurotoxicant, industry is on the hunt for an alternative. (foodnavigator.com)
  • Pure n -hexane is a colorless liquid with a slightly disagreeable odor. (cdc.gov)
  • If you have been exposed to harmful amounts of n -hexane, the amount of one of its breakdown products will probably be increased in your urine. (cdc.gov)
  • Pure n -hexane is used in laboratories. (cdc.gov)
  • Global N-Hexane Market Size, Share, Growth, Trends and Forecast 2018-2023 : Top Key Players - ExxonMobil Corporation, Royal Dutch Shell PLC, Indian Oil Corp. Ltd. (sbwire.com)
  • Global n-Hexane Market, 2018-2023, is a market research report by KD Market Insights that offers extensive and highly detailed current and future market trends in the global and regional/market. (sbwire.com)
  • Global n-Hexane Market was held at USD XXX Million in 2017 and is expected to garner USD XXX Million by the end of 2023. (sbwire.com)
  • The report reviews the preliminary estimates for 2018 and forecasts for growth in n-Hexane Market demand for 2019-2023. (sbwire.com)
  • Naphthalene is non-polar so it is soluble in hexane, but almost insoluble in water. (swelec.com)
  • Naphthalene solubility test with hexane was found to be soluble. (swelec.com)
  • Naphthalene is non-polar so it is soluble in hexane, but almost When did organ music become associated with baseball? (swelec.com)
  • 1) Malic Acid in Water 2) Naphthalene in Water 3) Amphetamine in Ethyl Alcohol 4) Aspirin in Water 5) Succinic Acid in Hexane 6) Ibuprofen in Diethyl Ether 7) 1-Decanol in Water For some of them, I already have the answer and for others, I'm not sure. (swelec.com)
  • The National Fire Protection Association (NFPA) has assigned n- hexane a health hazard identification code of 1 (slight) and flammability code of 3 (serious) (NFPA 1994). (cdc.gov)
  • n- Hexane can react vigorously with oxidizing materials such as liquid chlorine, concentrated oxygen, and sodium hypochlorite. (cdc.gov)
  • The EyeCGas OGI camera has a minimum detectable leak rate for Hexane of approximately 0.3 grams/hour (1 gallon/year liquid Hexane). (opgal.com)
  • In contrast, the hexane monolayer exhibits polymorphism in that the solid HB phase transforms to a rectangular‐centered structure with a short coherence length in coexistence with a fluid phase. (umsystem.edu)
  • Commercial samples of n-hexane however often contains methylcyclopentane, which features tertiary C-H bonds, which are incompatible with some radical reactions. (wikipedia.org)
  • The urinary excretion of the n-hexane metabolite 2,5-hexanedione (HD) was determined in four shoe factory workers during four workingdays that were preceded by four free days and followed by two free days. (bmj.com)
  • If n -hexane is spilled on the ground, most of it will evaporate before it can soak into the soil. (cdc.gov)
  • Hexane was attributed as the cause of an explosion that occurred in the National University of Río Cuarto, Argentina on 5 December 2007, due to a hexane spill near a heat-producing machine that exploded, producing a fire that killed one student and injured 24 more. (wikipedia.org)
  • In commercial grades of n- hexane, some of the constituents are purposefully added as denaturants, often to discourage the abuse of the chemical to induce " highs " through sniffing or inhalation (Altenkirch et al. (cdc.gov)
  • Hexane losses can occur throughout the process, including in the extractor, in the stripper, and in the waste water boiler. (opgal.com)
  • used industrial plant sale soy hexane crusher soy bean crush plant and hexane hazards - beltconveyers.net Articles Crusher Machine. (barvy-eshop.cz)
  • The effect of molecular steric properties on the melting of quasi‐two‐dimensional solids is investigated by comparing results of molecular dynamics simulations of the melting of butane and hexane monolayers adsorbed on the basal‐plane surface of graphite. (umsystem.edu)
  • The molecular weight of hexane is 86.178 g/mol. (yourquickinformation.com)
  • Some people abuse products containing n-hexane by inhaling it to get "high. (cdc.gov)
  • Teach your children and teenagers the dangers of inhaling products that contain n -hexane. (cdc.gov)
  • n-Hexane is sometimes used as a denaturant for alcohol, and as a cleaning agent in the textile, furniture, and leather industries. (wikipedia.org)
  • The report also highlights the competitive landscape of the global n-Hexane Market, positioning of all the major players in industry. (sbwire.com)
  • The formation of gauche molecules is essential for the melting process in the hexane monolayer but unimportant for butane. (umsystem.edu)
  • and both napthalene and hexane are non-polar molecules. (swelec.com)
  • Hence, there's a higher number of cyclohexane molecules in a given molecule when compared with hexane. (yourquickinformation.com)