Growth Disorders: Deviations from the average values for a specific age and sex in any or all of the following: height, weight, skeletal proportions, osseous development, or maturation of features. Included here are both acceleration and retardation of growth.Silver-Russell Syndrome: Genetically and clinically heterogeneous disorder characterized by low birth weight, postnatal growth retardation, facial dysmorphism, bilateral body asymmetry, and clinodactyly of the fifth fingers. Alterations in GENETIC IMPRINTING are involved. Hypomethylation of IGF2/H19 locus near an imprinting center region of chromosome 11p15 plays a role in a subset of Silver-Russell syndrome. Hypermethylation of the same chromosomal region, on the other hand, can cause BECKWITH-WIEDEMANN SYNDROME. Maternal UNIPARENTAL DISOMY for chromosome 7 is known to play a role in its etiology.Dwarfism: A genetic or pathological condition that is characterized by short stature and undersize. Abnormal skeletal growth usually results in an adult who is significantly below the average height.Beckwith-Wiedemann Syndrome: A syndrome of multiple defects characterized primarily by umbilical hernia (HERNIA, UMBILICAL); MACROGLOSSIA; and GIGANTISM; and secondarily by visceromegaly; HYPOGLYCEMIA; and ear abnormalities.Hair Follicle: A tube-like invagination of the EPIDERMIS from which the hair shaft develops and into which SEBACEOUS GLANDS open. The hair follicle is lined by a cellular inner and outer root sheath of epidermal origin and is invested with a fibrous sheath derived from the dermis. (Stedman, 26th ed) Follicles of very long hairs extend into the subcutaneous layer of tissue under the SKIN.Genomic Imprinting: The variable phenotypic expression of a GENE depending on whether it is of paternal or maternal origin, which is a function of the DNA METHYLATION pattern. Imprinted regions are observed to be more methylated and less transcriptionally active. (Segen, Dictionary of Modern Medicine, 1992)Body Height: The distance from the sole to the crown of the head with body standing on a flat surface and fully extended.Insulin-Like Growth Factor II: A well-characterized neutral peptide believed to be secreted by the LIVER and to circulate in the BLOOD. It has growth-regulating, insulin-like and mitogenic activities. The growth factor has a major, but not absolute, dependence on SOMATOTROPIN. It is believed to be a major fetal growth factor in contrast to INSULIN-LIKE GROWTH FACTOR I, which is a major growth factor in adults.Bipolar Disorder: A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence.Mental Disorders: Psychiatric illness or diseases manifested by breakdowns in the adaptational process expressed primarily as abnormalities of thought, feeling, and behavior producing either distress or impairment of function.Anxiety Disorders: Persistent and disabling ANXIETY.Mood Disorders: Those disorders that have a disturbance in mood as their predominant feature.Diagnostic and Statistical Manual of Mental Disorders: Categorical classification of MENTAL DISORDERS based on criteria sets with defining features. It is produced by the American Psychiatric Association. (DSM-IV, page xxii)Depressive Disorder, Major: Marked depression appearing in the involution period and characterized by hallucinations, delusions, paranoia, and agitation.Attention Deficit Disorder with Hyperactivity: A behavior disorder originating in childhood in which the essential features are signs of developmentally inappropriate inattention, impulsivity, and hyperactivity. Although most individuals have symptoms of both inattention and hyperactivity-impulsivity, one or the other pattern may be predominant. The disorder is more frequent in males than females. Onset is in childhood. Symptoms often attenuate during late adolescence although a minority experience the full complement of symptoms into mid-adulthood. (From DSM-V)Depressive Disorder: An affective disorder manifested by either a dysphoric mood or loss of interest or pleasure in usual activities. The mood disturbance is prominent and relatively persistent.Obsessive-Compulsive Disorder: An anxiety disorder characterized by recurrent, persistent obsessions or compulsions. Obsessions are the intrusive ideas, thoughts, or images that are experienced as senseless or repugnant. Compulsions are repetitive and seemingly purposeful behavior which the individual generally recognizes as senseless and from which the individual does not derive pleasure although it may provide a release from tension.Stress Disorders, Post-Traumatic: A class of traumatic stress disorders with symptoms that last more than one month. There are various forms of post-traumatic stress disorder, depending on the time of onset and the duration of these stress symptoms. In the acute form, the duration of the symptoms is between 1 to 3 months. In the chronic form, symptoms last more than 3 months. With delayed onset, symptoms develop more than 6 months after the traumatic event.Autistic Disorder: A disorder beginning in childhood. It is marked by the presence of markedly abnormal or impaired development in social interaction and communication and a markedly restricted repertoire of activity and interest. Manifestations of the disorder vary greatly depending on the developmental level and chronological age of the individual. (DSM-V)Phobic Disorders: Anxiety disorders in which the essential feature is persistent and irrational fear of a specific object, activity, or situation that the individual feels compelled to avoid. The individual recognizes the fear as excessive or unreasonable.Child Development Disorders, Pervasive: Severe distortions in the development of many basic psychological functions that are not normal for any stage in development. These distortions are manifested in sustained social impairment, speech abnormalities, and peculiar motor movements.Psychotic Disorders: Disorders in which there is a loss of ego boundaries or a gross impairment in reality testing with delusions or prominent hallucinations. (From DSM-IV, 1994)Substance-Related Disorders: Disorders related to substance abuse.

*  What Is a Growth Disorder?

Growth disorders include:. Failure to thrive, which isn't a specific growth disorder itself, but can be a sign of an underlying ... Diagnosing a Growth Disorder. The tests a doctor may recommend to detect a growth disorder depend on the findings at each step ... Treating a Growth Disorder. Although the treatment of a growth problem usually isn't urgent, earlier diagnosis and treatment ... which are not growth disorders:. Constitutional growth delay: This condition describes children who are small for their ages ...
https://rchsd.org/health-articles/what-is-a-growth-disorder/

*  Female Hypoactive Sexual Desire Disorder Market: Global Industry Size, Analysis, Innovation, Overview, Growth, Share and...

Global Female Hypoactive Sexual Desire Disorder Market , Industry Size, Share, Research, Reviews, Analysis, Strategies, ... Female Hypoactive Sexual Desire Disorder Market: Global Industry Size, Analysis, Innovation, Overview, Growth, Share and ... Hypoactive sexual desire disorder (HSDD) is an absence of sexual fantasies and desire for sexual activity. The predisposing ... Latest Pharmaceutical and Healthcare disease pipeline guide Female Hypoactive Sexual Desire Disorder Pipeline Review, H1 2017, ...
https://medgadget.com/2017/04/female-hypoactive-sexual-desire-disorder-market-global-industry-size-analysis-innovation-overview-growth-share-and-forecasts.html

*  Disrupted Sleep Speeds Up Tumor Growth - Sleep Apnea Treatment - Sleep Apnea, Snoring, Sleeping Disorders

... found between disrupted sleep and increased tumor growth and aggressiveness. These differences are believed to exist because of ... Mice that were woken up at two-minute intervals showed tumor growth at twice the rate of the mice that were allowed to sleep ... The positive result of this study is the finding of proper sleep being a way to prevent a high rate of cancerous tumor growth. ... This is the first study that shows how fragmented sleep affects tumors rate of growth and aggression. The study was supported ...
https://fusionsleep.com/blogs/disrupted-sleep-speeds-up-tumor-growth

*  NIOSHTIC-2 Publications Search - 20033249 - Nicotine- or epinephrine-induced uteroplacental vasoconstriction and fetal growth...

We examined the relationship between nicotine-induced vasoconstriction in pregnant rat dams and fetal growth during the third ... Growth-disorders; Growth-factors; Growth-inhibition; Growth-rate; Chemical-composition; Chemical-indicators; Chemical-reactions ... We examined the relationship between nicotine-induced vasoconstriction in pregnant rat dams and fetal growth during the third ... Nicotine- or epinephrine-induced uteroplacental vasoconstriction and fetal growth in the rat.. ...
https://cdc.gov/niosh/nioshtic-2/20033249.html

*  Faculty | Baylor College of Medicine | Houston, Texas

Rett Syndrome; Methyl-CpG-Binding Protein 2; Growth Disorders; Lactation; Dietary Proteins ... Functional Gastrointestinal Disorders in Children; Gastrointestinal Development; Inflammatory Bowel Disease; Parenteral ...
https://bcm.edu/departments/pediatrics/sections-divisions-centers/childrens-nutrition-research-center/faculty/?PMID=9544

*  Radiation- and Alkylator-free Bone Marrow Transplantation Regimen for Patients With Dyskeratosis Congenita - Full Text View -...

Growth Disorders. Neurobehavioral Manifestations. Neurologic Manifestations. Nervous System Diseases. Signs and Symptoms. ... Neurodevelopmental Disorders. Mental Disorders. Craniofacial Abnormalities. Musculoskeletal Abnormalities. Musculoskeletal ... Fetal Growth Retardation. Intellectual Disability. Microcephaly. Disease. Pathologic Processes. Anemia. Hematologic Diseases. ... DC is part of a spectrum of telomere biology disorders, which include some forms of inherited idiopathic aplastic anemia, ...
https://clinicaltrials.gov/ct2/show/study/NCT01659606?view=record

*  Factitious disorder - Overview - Mayo Clinic

... a serious mental disorder in which someone deceives others by appearing sick, by purposely getting sick or by self-injury. ... Factitious disorder-by-proxy simulating fetal growth restriction. Obstetrics and Gynecology. 2015;125:732. ... www.merckmanuals.com/professional/psychiatric-disorders/somatic-symptom-and-related-disorders/factitious-disorder-imposed-on- ... Factitious disorder is a serious mental disorder in which someone deceives others by appearing sick, by purposely getting sick ...
https://mayoclinic.org/diseases-conditions/factitious-disorder/home/ovc-20322568?footprints=mine&reDate=29062016

*  Handbook of Growth and Growth Monitoring in Health and Disease - Google Books

Effects of disease on growth. Methods and standards for assessment of growth, and more. The Handbook of Growth and Growth ... Postnatal growth in normal and abnormal situations. Cells and growth of tissues. Sensory growth and development. ... The Handbook of Growth and Growth Monitoring in Health and Disease brings this significant and complex field together in one ... each body part or region has its own unique growth patterns. Yet at the individual and population levels, growth patterns are ...
https://books.google.com.au/books/about/Handbook_of_Growth_and_Growth_Monitoring.html?id=9FQXunlUvz0C&redir_esc=y&hl=en

*  Blood Test: IGF Binding Protein-3 (IGFBP-3)

... test is to see if a person is producing a normal amount of human growth hormone. ... In this way, the IGFBP-3 test is used to check for pituitary gland disorders and abnormalities in growth hormone production. ... Insulin-like growth factor binding protein 3 (IGFBP-3) is the main carrier of somatomedin C (also called insulin-like growth ... The test also might be used to monitor treatment of growth disorders. ...
kidshealth.org/Nemours/en/parents/test-igfbp3.html

*  Face swelling and Myopathy - Symptom Checker - check medical symptoms at RightDiagnosis

AND Disorders primarily affecting skeletal growth (1 match). *AND Drowsiness in pregnancy (1 match) ... AND Sudden onset of hand swelling related to endocrine disorders (2 matches) ...
wrongdiagnosis.com/cosymptoms/face-swelling/myopathy.htm

*  Growth Disorders

Everyone grows and matures differently. Usually, this is totally normal. A growth disorder, however, means that a kid has abnormal growth - for example, growing a lot slower or a lot faster than other kids the same age.
kidshealth.org/PrimaryChildrens/en/kids/growth-disorders.html

*  Gene Expression Literature Detail

J:201436 Chang I, Bramall AN, Baynash AG, Rattner A, Rakheja D, Post M, Joza S, McKerlie C, Stewart DJ, McInnes RR, Yanagisawa M, Endothelin-2 deficiency causes growth retardation, hypothermia, and emphysema in mice. J Clin Invest. 2013 Jun 3;123(6):2643-53 ...
informatics.jax.org/gxdlit/key/159994

Idiopathic short statureAlan Beckwith: Alan Beckwith is an American actor born in Tyrone, Pennsylvania on January 2, 1952. Graduated from high school in 1969 & Penn State University in 1972 with a B.Dwarfism: Dwarf}}Beckwith–Wiedemann syndromeHair follicle nevus: Hair follicle nevus (also known as a "Vellus hamartoma") is a cutaneous condition that presents as a small papule from which fine hairs protrude evenly from the surface.Waterladder pumpInsulin-like growth factor II IRESBipolar disorderMental disorderSocial anxiety disorderSchizophreniaBrexpiprazoleAdult attention deficit hyperactivity disorderRelationship obsessive–compulsive disorder: In psychology, relationship obsessive–compulsive disorder (ROCD) is a form of obsessive-compulsive disorder focusing on intimate relationships (whether romantic or non-romantic). Such obsessions can become extremely distressing and debilitating, having negative impacts on relationships functioning.Oneirology: Oneirology (; from Greek [oneiron, "dream"; and -λογία], ["the study of") is the scientific study of [[dream]s. Current research seeks correlations between dreaming and current knowledge about the functions of the brain, as well as understanding of how the brain works during dreaming as pertains to memory formation and mental disorders.Focus on Autism and Other Developmental Disabilities: Focus on Autism and Other Developmental Disabilities is a peer-reviewed academic journal covering the field of special education. The editors-in-chief are Alisa K.Claustrophobia: Claustrophobia is the fear of having no escape and being in closed or small space or room It is typically classified as an anxiety disorder and often results in panic attack, and can be the result of many situations or stimuli, including elevators crowded to capacity, windowless rooms, and even tight-necked clothing. The onset of claustrophobia has been attributed to many factors, including a reduction in the size of the amygdala, classical conditioning, or a genetic predisposition to fear small spaces.Relationship Development Intervention: Relationship Development Intervention (RDI) is a trademarked proprietary treatment program for autism spectrum disorders (ASD), based on the belief that the development of dynamic intelligence is the key to improving the quality of life for individuals with autism. The program's core philosophy is that individuals with autism can participate in authentic emotional relationships if they are exposed to them in a gradual, systematic way.DSM-IV Codes (alphabetical): __FORCETOC__Substance-related disorder

(1/1579) Pathological changes in chickens, ducks and turkeys fed high levels of rapeseed oil.

Rations containing 25% of either regular rapeseed oil (36% erucic acid), Oro rapeseed oil (1.9% erucic acid), soybean oil or a mixture of lard and corn oil were fed to chickens, ducks and turkeys. The regular rapeseed oil ration caused growth depression, increased feed conversion and anemia in all species. All the ducks and some of the chickens fed the regular rapeseed oil ration died. These dead birds were affected with hydropericardium and ascites. No deaths in the turkeys could be attributed to the regular rapeseed oil ration but some turkeys fed this ration had degenerative foci characterized by infiltrations of histiocytic and giant cells in the myocardium. Severe fatty change in the heart, skeletal muscles, spleen and kidney was found at an early age in all birds fed the regular rapeseed oil ration. Less severe fatty change but no other lesions were found in birds fed the Oro rapeseed oil and soybean oil rations.  (+info)

(2/1579) Changes in body composition and leptin levels during growth hormone (GH) treatment in short children with various GH secretory capacities.

OBJECTIVE: The aim of this study was to follow changes in body composition, estimated by dual-energy X-ray absorptiometry (DXA), in relation to changes in leptin during the first year of GH therapy in order to test the hypothesis that leptin is a metabolic signal involved in the regulation of GH secretion in children. DESIGN AND METHODS: In total, 33 prepubertal children were investigated. Their mean (S.D.) chronological age at the start of GH treatment was 11.5 (1.6) years, and their mean height was -2.33 (0.38) S.D. scores (SDS). GH was administered subcutaneously at a daily dose of 0.1 (n=26) or 0.2 (n=7) IU/kg body weight. Ten children were in the Swedish National Registry for children with GH deficiency, and twenty-three children were involved in trials of GH treatment for idiopathic short stature. Spontaneous 24-h GH secretion was studied in 32 of the children. In the 24-h GH profiles, the maximum level of GH was determined and the secretion rate estimated by deconvolution analysis (GHt). Serum leptin levels were measured at the start of GH treatment and after 10 and 30 days and 3, 6 and 12 months of treatment. Body composition measurements, by DXA, were performed at baseline and 12 months after the onset of GH treatment. RESULTS: After 12 months of GH treatment, mean height increased from -2.33 to -1.73 SDS and total body fat decreased significantly by 3.0 (3.3)%. Serum leptin levels were decreased significantly at all time points studied compared with baseline. There was a significant correlation between the change in total body fat and the change in serum leptin levels during the 12 months of GH treatment, whereas the leptin concentration per unit fat mass did not change. In a multiple stepwise linear regression analysis with 12 month change in leptin levels as the dependent variable, the percentage change in fat over 12 months, the baseline fat mass (%) of body mass and GHt accounted for 24.0%, 11.5% and 12.2% of the variability respectively. CONCLUSIONS: There are significant correlations between changes in leptin and fat and endogenous GH secretion in short children with various GH secretory capacities. Leptin may be the messenger by which the adipose tissue affects hypothalamic regulation of GH secretion.  (+info)

(3/1579) Separate and joint effects of micronutrient deficiencies on linear growth.

Recent studies have investigated the effect of micronutrient deficiencies on growth stunting, with special attention toward the effect of zinc, iron, vitamin A and iodine deficiencies. In Mexico, the prevalence of growth stunting in children <5 y old is approximately 24%; it is higher in rural areas and lower in urban areas. In an initial study, the effect of zinc and/or iron supplementation on linear growth was investigated in a longitudinal, placebo-controlled design. After 12 mo of supplementation, there was no difference between the groups supplemented with zinc, iron or zinc plus iron and the placebo group. At baseline, 82% of the children in this study were deficient in at least two out of the five micronutrients that were determined, and 73% were anemic. In another study, a mixture of those micronutrients that were documented to be lacking in Mexican children was formulated in a supplement and given to Mexican children over a period of 12 mo in a longitudinal, placebo-controlled, supplementation design. Children in the low and medium socioeconomic status grew about 1 cm more than similar children in the placebo group. This difference was not found in children of high socioeconomic status. It is suggested that, in most cases, growth stunting is associated with marginal deficiencies of several micronutrients and that in populations with multiple micronutrient deficiencies, the effect on linear growth of supplementation with single nutrients will not be significant. Supplementation with multiple micronutrients is expected to be more effective, but even in that case the actual increment in height was less than the expected potential increment.  (+info)

(4/1579) Burden of infection on growth failure.

The high prevalence of infections among children living in poor areas of developing countries impairs linear growth in these populations. Acute, invasive infections, which provoke a systemic response (e.g., dysentery and pneumonia), and chronic infections, which affect the host over a sustained period (e.g., gut helminth infections), have a substantial effect on linear growth. Such infections can diminish linear growth by affecting nutritional status. This occurs because infections may decrease food intake, impair nutrient absorption, cause direct nutrient losses, increase metabolic requirements or catabolic losses of nutrients and, possibly, impair transport of nutrients to target tissues. In addition, induction of the acute phase response and production of proinflammatory cytokines may directly affect the process of bone remodeling that is required for long bone growth. Infection of cells directly involved in bone remodeling (osteoclasts or osteoblasts) by specific viruses may also directly affect linear growth. Many interventions are possible to diminish the effect of infection on growth. Prevention of disease through sanitation, vector control, promotion of breast-feeding and vaccination is crucial. Appropriate treatment of infections (e.g., antibiotics for pneumonia) as well as supportive nutritional therapy (again including breast-feeding) during and after recovery, is also important. Targeted therapeutic interventions to decrease the prevalence of gut helminth infections may also be appropriate in areas in which such infections are widespread. Such interventions are of public health benefit not only because they reduce the incidence or severity of infections, but also because they decrease the long-term detrimental effect of malnutrition on populations.  (+info)

(5/1579) Retarded growth and deficits in the enteric and parasympathetic nervous system in mice lacking GFR alpha2, a functional neurturin receptor.

Glial cell line-derived neurotrophic factor (GDNF) and a related protein, neurturin (NTN), require a GPI-linked coreceptor, either GFR alpha1 or GFR alpha2, for signaling via the transmembrane Ret tyrosine kinase. We show that mice lacking functional GFR alpha2 coreceptor (Gfra2-/-) are viable and fertile but have dry eyes and grow poorly after weaning, presumably due to malnutrition. While the sympathetic innervation appeared normal, the parasympathetic cholinergic innervation was almost absent in the lacrimal and salivary glands and severely reduced in the small bowel. Neurite outgrowth and trophic effects of NTN at low concentrations were lacking in Gfra2-/- trigeminal neurons in vitro, whereas responses to GDNF were similar between the genotypes. Thus, GFR alpha2 is a physiological NTN receptor, essential for the development of specific postganglionic parasympathetic neurons.  (+info)

(6/1579) Cloning and expression of a novel chicken sulfotransferase cDNA regulated by GH.

We have used mRNA differential display to compare gene expression in normal and GH receptor-deficient dwarf chickens, and report here the characterization of one differentially expressed gene, which shows significant sequence identity to the sulfotransferase gene family. Partial cDNA clones were isolated from a chicken liver cDNA library and an additional sequence was obtained using 5' rapid amplification of cDNA ends. A complete cDNA probe hybridizes to three transcripts (2.4, 2.0 and 1.45 kb) on Northern blots of chicken liver RNA, which differ in the length of the 3' untranslated region. All three transcripts are expressed at higher levels in normal vs dwarf chickens, as expected for a GH-regulated gene. The expression of this sulfotransferase mRNA was also detected in skeletal muscle, but not other tissues. The administration of GH to chickens increased the hepatic expression within 1 h, suggesting this sulfotransferase could be directly regulated by GH. Sulfotransferase activity, using estradiol or corticosterone as substrate, is detected in cells transfected with an expression vector containing the full-length cDNA. The sequence of this sulfotransferase does not show significant similarity with any subfamily of the sulfotransferases and its endogenous substrate is presently unknown. However, we speculate that GH activation of sulfotransferase activity could play a role in reducing concentrations of growth-antagonistic steroid hormones in GH target tissues. These results demonstrate the usefulness of differential display in this model system to identify genes that play a role in mediating GH action.  (+info)

(7/1579) Growth hormone treatment in young children with Down's syndrome: effects on growth and psychomotor development.

BACKGROUND: Learning disability and short stature are cardinal signs of Down's syndrome. Insulin-like growth factor I (IGF-I), regulated by growth hormone (GH) from about 6 months of age, may be involved in brain development. AIMS: To study long term effects of GH on linear growth and psychomotor development in young children with Down's syndrome. Study design-Fifteen children with Down's syndrome were treated with GH for three years from the age of 6 to 9 months (mean, 7.4). Linear growth, psychomotor development, skeletal maturation, serum concentrations of IGF-I and its binding proteins (BPs), and cerebrospinal fluid (CSF) concentrations of IGF-II were studied. RESULTS: The mean height of the study group increased from -1.8 to -0.8 SDS (Swedish standard) during treatment, whereas that of a Down's syndrome control group fell from -1.7 to -2.2 SDS. Growth velocity declined after treatment stopped. Head growth did not accelerate during treatment. No significant difference in mental or gross motor development was found. The low concentrations of serum IGF-I and IGFBP-3 became normal during GH treatment. CONCLUSIONS: GH treatment results in normal growth velocity in Down's syndrome but does not affect head circumference or mental or gross motor development. Growth velocity declines after treatment stops.  (+info)

(8/1579) Generalised uridine diphosphate galactose-4-epimerase deficiency.

The generalised form of epimerase deficiency galactosaemia has been described in only two children from unrelated families. Their progress is reported and three other affected children from these families are described. The initial presentation was similar to classic galactosaemia. Despite treatment all have shown poor growth and moderate learning difficulties. Three have sensorineural deafness and four have pronounced dysmorphic features. The two older female patients have normal pubertal development.  (+info)



Endocrine


  • Endocrine diseases (diseases involving hormones, the chemical messengers of the body) involve a deficiency or excess of hormones and can be responsible for growth failure during childhood and adolescence. (rchsd.org)
  • Blood levels of both these proteins are controlled by human growth hormone (hGH), a hormone that's produced by the pituitary gland, a pea-sized gland in the brain that works with the endocrine system. (kidshealth.org)
  • History of endocrine, dermatology, or immune system disorders known to alter hair growth (ie. (clinicaltrials.gov)

fetal


  • Nicotine- or epinephrine-induced uteroplacental vasoconstriction and fetal growth in the rat. (cdc.gov)
  • We examined the relationship between nicotine-induced vasoconstriction in pregnant rat dams and fetal growth during the third trimester of pregnancy. (cdc.gov)
  • We conclude that vasoconstriction alone as a result of nicotine or epinephrine administration during the last trimester of gestation does not necessarily reduce nutrient supply to the fetus and does not affect fetal growth in rats. (cdc.gov)
  • Factitious disorder-by-proxy simulating fetal growth restriction. (mayoclinic.org)

genetic


  • Turner syndrome , one of the most common genetic growth disorders, occurs in girls and is a syndrome in which there's a missing or abnormal X chromosome. (rchsd.org)
  • Yet at the individual and population levels, growth patterns are sensitive to adverse conditions, genetic predispositions, and environmental changes. (google.com.au)
  • To demonstrate the latest diagnostic and therapeutic approaches for genetic disorders. (allconferences.com)
  • Apert syndrome, also known as acrocephalosyndactyly type I (ACS1), is a rare genetic disorder that is apparent at birth (congenital). (rarediseases.org)

2017


  • Latest Pharmaceutical and Healthcare disease pipeline guide Female Hypoactive Sexual Desire Disorder Pipeline Review, H1 2017, provides an overview of the Female Hypoactive Sexual Desire Disorder (Women's Health) pipeline landscape. (medgadget.com)
  • Global Markets Direct's Pharmaceutical and Healthcare latest pipeline guide Female Hypoactive Sexual Desire Disorder Pipeline Review, H1 2017, provides comprehensive information on the therapeutics under development for Female Hypoactive Sexual Desire Disorder (Women's Health), complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. (medgadget.com)

Hypothyroidism


  • Hypothyroidism is a condition in which the thyroid gland fails to make enough thyroid hormone, which is essential for normal bone growth. (rchsd.org)

symptoms


  • These children don't have any signs or symptoms of diseases that affect growth. (rchsd.org)
  • This term applies to short children who don't have any symptoms of diseases that affect their growth. (rchsd.org)
  • Other symptoms or physical signs in kids with these illnesses usually give clues as to the disease causing the growth delay. (rchsd.org)
  • Factitious disorder symptoms can range from mild (slight exaggeration of symptoms) to severe (previously called Munchausen syndrome). (mayoclinic.org)
  • Although people with factitious disorder know they are causing their symptoms or illnesses, they may not understand the reasons for their behaviors or recognize themselves as having a problem. (mayoclinic.org)
  • Symptoms such as short stature or excessive growth (gigantism) may warrant an IGFBP-3 test. (kidshealth.org)
  • Both moderate and severe levels of SE were associated with psychopathological symptoms (anxiety, depression, attention-deficit/hyperactivity disorder) both concurrently and prospectively. (aappublications.org)

pituitary


  • Growth hormone deficiency is a disorder that involves the pituitary gland (the small gland at the base of the brain that secretes several hormones, including growth hormone). (rchsd.org)
  • A damaged or malfunctioning pituitary gland may not produce enough hormones for normal growth. (rchsd.org)
  • The pituitary gland regulates growth and the function of other glands. (kidshealth.org)
  • In this way, the IGFBP-3 test is used to check for pituitary gland disorders and abnormalities in growth hormone production. (kidshealth.org)

food intake


  • Because moderate levels of selective eating were associated with impairment, selective eating falls within the diagnosis of avoidant/restrictive food intake disorder. (aappublications.org)
  • To better understand the pathophysiological mechanisms that underlie weight disorders, increasing attention is being paid to central regulatory elements in energy homeostasis, including food intake and energy expenditure. (clinicaltrials.gov)

gastrointestinal


  • An update about pediatric gastrointestinal disorders including celiac disease and gastro-eosophageal reflux disease. (allconferences.com)

abnormal


  • Postnatal growth in normal and abnormal situations. (google.com.au)

hormone


  • The main reason doctors order the IGFBP-3 test is for its usefulness as an indicator of whether someone is producing a normal amount of human growth hormone. (kidshealth.org)

patterns


  • books.google.com.au - Growth is one of the human body's most intricate processes: each body part or region has its own unique growth patterns. (google.com.au)

regulation


  • Working hypothesis and aims: We hypothesize that mutations in ghrelin or in its receptor, GHSR, affect appetite regulation and cause growth and eating disorders. (clinicaltrials.gov)

bones


  • The pressure of continued brain growth distorts various bones of the skull and the face. (rarediseases.org)

children


  • But others may have an actual growth disorder, which is any type of problem that prevents kids from meeting realistic expectations of growth , from failure to gain height and weight in young children to short stature or delayed sexual development in teens. (rchsd.org)
  • Factitious disorder also can happen when family members or caregivers falsely present others, such as children, as being ill, injured or impaired. (mayoclinic.org)

Treatment


  • With both constitutional growth delay and familial short stature, kids and families need to be reassured that the child does not have a disease or medical condition that poses a threat to health or that requires treatment. (rchsd.org)
  • The test also might be used to monitor treatment of growth disorders. (kidshealth.org)

disease


  • Factitious disorder in Crohn's disease: Recurrent pancytopenia caused by surreptitious ingestion of 6-mercaptopurine. (mayoclinic.org)
  • Effects of disease on growth. (google.com.au)

rate of growth


  • This is the first study that shows how fragmented sleep affects tumors rate of growth and aggression. (fusionsleep.com)

normal


  • Kids with familial short stature still have growth spurts and enter puberty at normal ages, but they usually will only reach a height similar to that of their parents. (rchsd.org)

problems


  • Failure to thrive , which isn't a specific growth disorder itself, but can be a sign of an underlying condition causing growth problems. (rchsd.org)
  • Factitious disorder is not the same as inventing medical problems for practical benefit, such as getting out of work or winning a lawsuit. (mayoclinic.org)

type


  • The pipeline guide evaluates Female Hypoactive Sexual Desire Disorder (Women's Health) therapeutics based on mechanism of action (MoA), drug target, route of administration (RoA) and molecule type. (medgadget.com)

However


  • However, poor growth can be the first sign of a problem in some. (rchsd.org)
  • However, medical and psychiatric help are critical for preventing serious injury and even death caused by the self-harm typical of this disorder. (mayoclinic.org)

condition


  • Although it's common for newborns to lose a little weight in the first few days, failure to thrive is a condition in which some infants continue to show slower-than-expected weight gain and growth. (rchsd.org)

common


sexual


  • They tend to reach puberty later than their peers do, with delay in the onset of sexual development and the pubertal growth spurt. (rchsd.org)
  • Hypoactive sexual desire disorder (HSDD) is an absence of sexual fantasies and desire for sexual activity. (medgadget.com)
  • The Female Hypoactive Sexual Desire Disorder (Women's Health) pipeline guide also reviews of key players involved in therapeutic development for Female Hypoactive Sexual Desire Disorder and features dormant and discontinued projects. (medgadget.com)
  • Female Hypoactive Sexual Desire Disorder (Women's Health) pipeline guide helps in identifying and tracking emerging players in the market and their portfolios, enhances decision making capabilities and helps to create effective counter strategies to gain competitive advantage. (medgadget.com)
  • The pipeline guide provides a snapshot of the global therapeutic landscape of Female Hypoactive Sexual Desire Disorder (Women's Health). (medgadget.com)
  • The pipeline guide reviews pipeline therapeutics for Female Hypoactive Sexual Desire Disorder (Women's Health) by companies and universities/research institutes based on information derived from company and industry-specific sources. (medgadget.com)
  • The pipeline guide reviews key companies involved in Female Hypoactive Sexual Desire Disorder (Women's Health) therapeutics and enlists all their major and minor projects. (medgadget.com)
  • Find and recognize significant and varied types of therapeutics under development for Female Hypoactive Sexual Desire Disorder (Women's Health). (medgadget.com)
  • Formulate corrective measures for pipeline projects by understanding Female Hypoactive Sexual Desire Disorder (Women's Health) pipeline depth and focus of Indication therapeutics. (medgadget.com)

human


  • cover every area of human growth, including: Intrauterine growth retardation. (google.com.au)

cases


  • Factitious disorder: A systematic review of 455 cases in the professional literature. (mayoclinic.org)
  • In rare cases, the disorder may be inherited as an autosomal dominant trait. (rarediseases.org)

Development


body


  • Insulin-like growth factor binding protein 3 (IGFBP-3) is the main carrier of somatomedin C (also called insulin-like growth factor-1, or IGF-1) in the body. (kidshealth.org)

close


  • One or both parents or other close relatives often had a similar "late-bloomer" growth pattern. (rchsd.org)