Fetal Viability
The Caenorhabditis elegans mel-11 myosin phosphatase regulatory subunit affects tissue contraction in the somatic gonad and the embryonic epidermis and genetically interacts with the Rac signaling pathway. (1/189)
Caenorhabditis elegans embryonic elongation is driven by cell shape changes that cause a contraction of the epidermal cell layer enclosing the embryo. We have previously shown that this process requires a Rho-associated kinase (LET-502) and is opposed by the activity of a myosin phosphatase regulatory subunit (MEL-11). We now extend our characterization and show that mel-11 activity is required both in the epidermis during embryonic elongation and in the spermatheca of the adult somatic gonad. let-502 and mel-11 reporter gene constructs show reciprocal expression patterns in the embryonic epidermis and the spermatheca, and mutations of the two genes have opposite effects in these two tissues. These results are consistent with let-502 and mel-11 mediating tissue contraction and relaxation, respectively. We also find that mel-11 embryonic inviability is genetically enhanced by mutations in a Rac signaling pathway, suggesting that Rac potentiates or acts in parallel with the activity of the myosin phosphatase complex. Since Rho has been implicated in promoting cellular contraction, our results support a mechanism by which epithelial morphogenesis is regulated by the counteracting activities of Rho and Rac. (+info)Differential and inefficient splicing of a broadly expressed Drosophila erect wing transcript results in tissue-specific enrichment of the vital EWG protein isoform. (2/189)
In this report, we document an unusual mode of tissue-enriched gene expression that is primarily mediated by alternative and inefficient splicing. We have analyzed posttranscriptional regulation of the Drosophila erect wing gene, which provides a vital neuronal function and is essential for the formation of certain muscles. Its predominant protein product, the 116-kDa EWG protein, a putative transcriptional regulator, can provide all known erect wing-associated functions. Moreover, consistent with its function, the 116-kDa protein is highly enriched in neurons and is also observed transiently in migrating myoblasts. In contrast to the protein distribution, we observed that erect wing transcripts are present in comparable levels in neuron-enriched heads and neuron-poor bodies of adult Drosophila. Our analyses shows that erect wing transcript consists of 10 exons and is alternatively spliced and that a subset of introns are inefficiently spliced. We also show that the 116-kDa EWG protein-encoding splice isoform is head enriched. In contrast, bodies have lower levels of transcripts that can encode the 116-kDa protein and greater amounts of unprocessed erect wing RNA. Thus, the enrichment of the 116-kDa protein in heads is ensured by tissue-specific alternative and inefficient splicing and not by transcriptional regulation. Furthermore, this regulation is biologically important, as an increased level of the 116-kDa protein outside the nervous system is lethal. (+info)Interferon-gamma contributes to the normalcy of murine pregnancy. (3/189)
Uterine natural killer (uNK) cells are transient, large, heavily granulated, maternal lymphocytes present on the mesometrial side of the pregnant mouse uterus. These cells contribute to normal implantation site development. Cytokine production, particularly interferon (IFN)-gamma, is a major function of most NK cell subsets. In this study, uNK cells were assessed for IFN-gamma production. Local concentrations of IFN-gamma were measured in the mesometrial regions of murine implantation sites between Days 6 and 16 of gestation. IFN-gamma was detected by ELISA at all days studied in a random-bred (CD1) and an inbred (BALB/c) strain of immune-competent mouse and in two immune-deficient strains, SCID (NK(+), T(-), B(-)) and tgepsilon26 (NK(-), T(-), B(+)). Concentrations of IFN-gamma per implantation site peaked at Day 10 of gestation in NK(+) strains but were low and relatively constant in NK(-) mice. To evaluate the functions of IFN-gamma at murine implantation sites, pregnancy was studied in homozygously mated IFN-gamma(-/-) and IFN-gammaRalpha(-/-) mice and their congenic controls. Primiparous but not multiparous IFN-gamma(-/-) mice experienced significant fetal loss. Primiparous IFN-gammaRalpha(-/-) carried full litters to term. Implantation site pathology was demonstrated in both strains of gene-deleted mice by light microscopy and ultrastructurally. This included elevated numbers of uNK cells that contained fewer and smaller granules and, after Day 10 of gestation, progressive necrosis and loss of decidua. The presence of a fetus able to produce IFN-gamma did not modify the phenotype of pregnant IFN-gamma(-/-) mice. This study indicates that during murine pregnancy, uNK cells are the main source of IFN-gamma on the mesometrial side of the uterus and that IFN-gamma contributes to normal health of the midgestational decidua. Furthermore, evidence is presented that IFN-gamma-producing cells exist in mesometrial regions of implantation sites that are neither NK nor T cells. (+info)Expression of the insulin-like growth factor-1 gene and its receptor in preimplantation mouse embryos; is it a marker of embryo viability? (4/189)
Recent studies have demonstrated the importance of insulin-like growth factors (IGF) in mouse preimplantation development. We examined IGF-1 and IGF-1 receptor (IGF-1R) gene expression in a single blastomere of an early mouse embryo and compared it with subsequent embryo development in culture. Fertilized eggs and 2-cell embryos were obtained by tubal flushing in superovulated and mated female mice. Single cells were removed from embryos at cleavage stage between 3 and 8 cells using the standard embryo biopsy techniques. Individual blastomeres from each embryo were then assayed for the presence of IGF-1 and IGF-1R mRNA using reverse transcription-polymerase chain reaction. The biopsied embryos were washed in medium and placed in co-culture with murine endometrial cells. Embryonic development in culture was assessed and blastocyst grading was performed. IGF-1 gene expression was then examined for an association with in-vitro development. Eighty-seven embryos were biopsied. IGF-1R gene expression was detected in the majority of embryos tested and IGF-1 gene expression was detected in 34 of 81 (42%) embryos. A significant association between IGF-1 expression and blastocyst formation in vitro was found (P < 0.01). There was no association between IGF-1R expression and subsequent embryo development. We conclude that IGF-1 gene expression could potentially be used as a marker of embryo quality. (+info)Drosophila myc regulates cellular growth during development. (5/189)
Transcription factors of the Myc proto-oncogene family promote cell division, but how they do this is poorly understood. Here we address the functions of Drosophila Myc (dMyc) during development. Using mosaic analysis in the fly wing, we show that loss of dMyc retards cellular growth (accumulation of cell mass) and reduces cell size, whereas dMyc overproduction increases growth rates and cell size. dMyc-induced growth promotes G1/S progression but fails to accelerate cell division because G2/M progression is independently controlled by Cdc25/String. We also show that the secreted signal Wingless patterns growth in the wing primordium by modulating dMyc expression. Our results indicate that dMyc links patterning signals to cell division by regulating primary targets involved in cellular growth and metabolism. (+info)PPAR gamma is required for placental, cardiac, and adipose tissue development. (6/189)
The nuclear hormone receptor PPAR gamma promotes adipogenesis and macrophage differentiation and is a primary pharmacological target in the treatment of type II diabetes. Here, we show that PPAR gamma gene knockout results in two independent lethal phases. Initially, PPAR gamma deficiency interferes with terminal differentiation of the trophoblast and placental vascularization, leading to severe myocardial thinning and death by E10.0. Supplementing PPAR gamma null embryos with wild-type placentas via aggregation with tetraploid embryos corrects the cardiac defect, implicating a previously unrecognized dependence of the developing heart on a functional placenta. A tetraploid-rescued mutant surviving to term exhibited another lethal combination of pathologies, including lipodystrophy and multiple hemorrhages. These findings both confirm and expand the current known spectrum of physiological functions regulated by PPAR gamma. (+info)PPAR gamma mediates high-fat diet-induced adipocyte hypertrophy and insulin resistance. (7/189)
Agonist-induced activation of peroxisome proliferator-activated receptor gamma (PPAR gamma) is known to cause adipocyte differentiation and insulin sensitivity. The biological role of PPAR gamma was investigated by gene targeting. Homozygous PPAR gamma-deficient embryos died at 10.5-11.5 dpc due to placental dysfunction. Quite unexpectedly, heterozygous PPAR gamma-deficient mice were protected from the development of insulin resistance due to adipocyte hypertrophy under a high-fat diet. These phenotypes were abrogated by PPAR gamma agonist treatment. Heterozygous PPAR gamma-deficient mice showed overexpression and hypersecretion of leptin despite the smaller size of adipocytes and decreased fat mass, which may explain these phenotypes at least in part. This study reveals a hitherto unpredicted role for PPAR gamma in high-fat diet-induced obesity due to adipocyte hypertrophy and insulin resistance, which requires both alleles of PPAR gamma. (+info)Developmental toxicity studies in rats and rabbits with 3,5,6-trichloro-2-pyridinol, the major metabolite of chlorpyrifos. (8/189)
3,5,6-Trichloro-2-pyridinol (TCP), the primary metabolite of chlorpyrifos and chlorpyrifos-methyl, was evaluated for potential developmental toxicity. Groups of 32-34 bred female Fischer 344 rats were given 0, 50, 100, or 150 mg TCP/kg/day by gavage on gestation days 6-15; the fetuses were evaluated on gestation day 21. Similarly, groups of 16 inseminated female New Zealand White rabbits were given 0, 25, 100, or 250 mg TCP/kg/day by gavage on gestation days 7-19, and fetuses were evaluated on gestation day 28. No clinical signs of toxicity attributed to TCP were noted in either species. In rats, at 150 mg/kg/day, maternal effects included slight decreases in feed consumption, significantly depressed body weight gain (25% relative to controls) resulting in significantly lower maternal terminal body weights, and increased relative liver weight. At 100 mg/kg/day, maternal body weight gain in rats was depressed approximately 22%. Among rabbits, maternal effects were limited to the group given 250 mg/kg/day, which lost an average of approximately 70 g during the treatment period (vs. 140 g in the controls). There were no effects on fetal weight or viability, nor were there significant increases in any fetal alteration in either species. A slightly higher (not statistically significant) than usual incidence of central nervous system anomalies occurred in rabbits, but these anomalies were found in both treated and control groups in this study as well as contemporaneous studies of unrelated compounds. This, and the fact that these anomalies were not seen with the parent compound, chlorpyrifos, suggest that their origin was spontaneous. Thus, TCP was not considered fetotoxic or teratogenic in either rats or rabbits, even at dose levels that produced maternal toxicity. (+info)Fetal viability is the point in pregnancy at which a fetus is considered capable of surviving outside the uterus, given appropriate medical support. Although there is no precise gestational age that defines fetal viability, it is generally considered to occur between 24 and 28 weeks of gestation. At this stage, the fetus has developed sufficient lung maturity and body weight, and the risk of neonatal mortality and morbidity significantly decreases. However, the exact definition of fetal viability may vary depending on regional standards, medical facilities, and individual clinical assessments.
Pregnancy is a physiological state or condition where a fertilized egg (zygote) successfully implants and grows in the uterus of a woman, leading to the development of an embryo and finally a fetus. This process typically spans approximately 40 weeks, divided into three trimesters, and culminates in childbirth. Throughout this period, numerous hormonal and physical changes occur to support the growing offspring, including uterine enlargement, breast development, and various maternal adaptations to ensure the fetus's optimal growth and well-being.
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Fetal viability - Wikipedia
Fetal Anesthesia Expert: Unborn Children Feel Pain, Even Before Viability - ONE OF US
Illegal Fetal Age/Viability Deception Scheme Uncovered By Operation Rescue At Tiller's Abortion Clinic | Operation Rescue
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Practitioner would determine fetal viability1
- Under the petition language, the patient's healthcare practitioner would determine fetal viability. (latimes.com)
Maternal4
- The constitutional amendment would prohibit abortion bans prior to fetal viability and in cases of maternal mortality risk. (feminist.org)
- Exposure concentrations were based on a dose range-finding study that demonstrated 25,000 ppm 2H4MBP did not induce excessive maternal toxicity or affect parturition, litter size, or pup viability. (nih.gov)
- The people who are getting abortions later in pregnancy are those who have incredibly heartbreaking situations, either some awful, terrible fetal anomaly that took a while to be diagnosed or some maternal medical condition that puts the mother's life at risk," said Mae Winchester, a Cleveland-based maternal fetal medicine specialist. (kxan.com)
- Noninvasive maternal screening for fetal chromosomal abnormalities should be offered to all pregnant women who have not already decided to have amniocentesis or chorionic villus sampling (CVS). (msdmanuals.com)
Gestational age5
- Medical viability is generally considered to be between 23 and 24 weeks gestational age. (wikipedia.org)
- Viability depends upon factors such as birth weight, gestational age, and the availability of advanced medical care. (wikipedia.org)
- Fetal viability is generally considered to begin at 23 or 24 weeks gestational age in the United States. (wikipedia.org)
- The target age for these surgeries, Paschall said, is between 21 and 25 weeks of gestational age, which happens to be precisely the age targeted in fetal pain abortion legislation. (oneofus.eu)
- Since then, many doctors have bemoaned the legal and political bastardization of the medical concept, arguing that viability is much more complex than gestational age alone. (californiahealthline.org)
Pregnancy7
- In Ireland, under the Health (Regulation of Termination of Pregnancy) Act 2018, fetal viability is defined as "the point in a pregnancy at which, in the reasonable opinion of a medical practitioner, the foetus is capable of survival outside the uterus without extraordinary life-sustaining measures. (wikipedia.org)
- As a result, judges have struck down certain states' so-called heartbeat laws, which tried to prohibit abortions after detection of a fetal heartbeat (as early as six weeks of pregnancy). (leaps.org)
- and basic obstetrics, such as pregnancy viability and fetal positioning. (news-medical.net)
- Private central London women's clinic specialising in pregnancy including blood tests, nuchal scans & all routine pregnancy scans, early pregnancy, viability & dating scans, 20 weeks anatomy scan, well-being scans, gender scans, growth & Doppler scans. (020.co.uk)
- Antenatal & pregnancy ultrasound scans covering early pregnancy, 3D / 4D baby scans, fetal growth, detail & anomaly, nuchal scan (Down's Syndrome test). (020.co.uk)
- Full range of antenatal scans from dating pregnancy through to nuchal translucency screening, detailed anatomy, Babybond 4D and foetal presentation scans. (020.co.uk)
- With modern medicine, that point, referred to as the point of viability, is typically about 23 weeks or 24 weeks into the pregnancy. (kxan.com)
Abortions9
- Operation Rescue recently conducted an undercover investigation of late-term abortions at George Tiller's Women's Health Care Services, in Wichita, Kansas, focusing on the determination of fetal age and viability. (operationrescue.org)
- Operation Rescue discovered compelling evidence that WHCS intentionally underestimates fetal age, and therefore viability, in order to avoid compliance with the Kansas ban on post-viability abortions. (operationrescue.org)
- Abortions Before Fetal Viability Are Legal: Might Science and the Change on the Supreme Court Undermine That? (leaps.org)
- For almost 50 years, the Supreme Court of the United States has struck down laws that ban all or most abortions, ruling that women's constitutional rights include choosing to end pregnancies before the point of viability. (leaps.org)
- In Ohio, no abortion procedures performed past 12-weeks gestation-more than 10 weeks before fetal viability-resulted in "failed abortions. (feminist.org)
- A proposal to ban abortions following fetal cardiac activity-around 6-weeks gestation-did not get enough signatures. (feminist.org)
- The court said Monday it would review next term whether all state laws that ban pre-viability abortions are unconstitutional. (kcur.org)
- The test case is from Mississippi, which bans most abortions after 15 weeks, significantly before fetal viability. (kcur.org)
- Jamie Corley of suburban St. Louis filed constitutional amendments Wednesday to allow abortions in cases of rape, incest and fatal abnormalities until fetal viability. (necn.com)
Abnormalities1
- The American College of Obstetricians and Gynecologists (ACOG) provides recommendations for screening for fetal chromosomal abnormalities and a chart to show the timing of prenatal testing for chromosomal abnormalities (see ACOG: Prenatal Genetic Testing Chart ). (msdmanuals.com)
Bovine serum7
- Therefore, we investigated the viability and differentiation of human osteoblast-like cells during replacement of fetal bovine serum in vitro. (elsevierpure.com)
- The aim of the present study is to replace the potentially infectious supplement fetal bovine serum during the cryopreservation procedure in order to perform future clinical trials. (elsevierpure.com)
- In the cell culture of cryopreserved and fresh osteoblast-like cells, we substituted Dulbecco's modification of Eagle's medium (DMEM)/Ham's F12 plus 1% penicillin/streptomycin with autologous serum, human serum albumin and Biseko® for fetal bovine serum. (elsevierpure.com)
- For the fourth treatment group, we removed fetal bovine serum without replacing it. (elsevierpure.com)
- DMEM/Ham's F12 plus 1% penicillin/streptomycin with fetal bovine serum served as the control group. (elsevierpure.com)
- These findings indicate that, for clinical purposes, fetal bovine serum can be removed for cryopreservation of iliac cancellous bone with minor loss of viability. (elsevierpure.com)
- The cellular fraction was processed and frozen with L-proline (1.5M) + trehalose (0.2M) or with DMSO + fetal bovine serum (FBS) as control. (bvsalud.org)
Ultrasound2
- Small hematomas on the surface of the placenta (subamniotic hemorrhage) are common at 18-20 weeks on ultrasound, but hemorrhages identified beneath the placenta, at the edge of the placenta, or behind an isolated area of the fetal membranes is of greater significance. (medscape.com)
- Ultrasound scans in Harley Street performed to the highest standard by sonographers trained in fetal medicine under Professor Kypros Nicolaides. (020.co.uk)
Serum1
- The women were followed by vaginal followed with serial ultrasounds to deter- sonography and monitoring of serum estra- mine fetal viability. (who.int)
Cell viability2
- GO-AgNPs induced significant cytotoxicity by the loss of cell viability, production of reactive oxygen species (ROS), cell cycle arrest, increasing leakage of lactate dehydrogenase (LDH) and level of Malondialdehyde (MDA), increasing expression of pro-apoptotic genes and decreasing expression of anti-apoptotic genes. (researchsquare.com)
- After 30 and 90 days, the samples were thawed, and cell viability was assessed using the MTT technique. (bvsalud.org)
California3
- California law generally bars the performance of an abortion past the point of fetal viability," he said. (californiahealthline.org)
- Current California law incorporates the viability limit from Roe , allowing abortion for any reason through most of the second trimester and after that only if the patient's or fetus's health is in danger. (californiahealthline.org)
- Even among legal scholars, there is no consensus about whether that means the viability standard in place now will remain if Proposition 1 is approved or if time limits on abortion will be eradicated in California. (californiahealthline.org)
Abortion bans1
- But with Monday's decision to take on the whole question of pre-viability abortion bans, that approach may now be on the way out, and a more direct approach on the way in - namely overturning Roe . (kcur.org)
Prohibit2
- The measure continues to prohibit abortion after 'fetal viability' -- approximately 22-24 weeks during gestation -- unless a doctor believes a pregnant patient's life or health is in danger, experts told AFP. (yahoo.com)
- Tracy Thomas , director of the Center for Constitutional Law at The University of Akron, Ohio , who focuses on gender and civil rights issues, told AFP on November 6: 'The amendment specifically says that the government may prohibit abortion after fetal viability at about 23 weeks. (yahoo.com)
Toxicity2
- Taken together, our study demonstrated that GO-AgNPs potentially induce oxidative damage to DNA, which result in toxicity and cell apoptosis in caprine fetal fibroblast cell due to an increased generation of ROS. (researchsquare.com)
- Embryo-Fetal toxicity: Can cause fetal harm. (nih.gov)
Anomaly1
- Fetal viability scans, nuchal & well being scan, fetal cardiac & anomaly scans, Chorion Villus Sampling (CVS). (020.co.uk)
Prenatal Development1
- In the prenatal cohort, F2 prenatal development (litter size, fetal weight, and morphology) was assessed on GD 21. (nih.gov)
Anesthesia1
- It's not even close," he told a newspaper about his status as the leading surgeon with experience with fetal anesthesia surgeries, "I've personally done around 260 now. (oneofus.eu)
Weeks10
- He asserted in 2007 congressional testimony on fetal pain legislation that "a fetus at 20 to 32 weeks of gestation would experience a much more intense pain than older infants or children or adults" because certain pain mechanisms are in play much earlier, while "fibers which dampen and modulate the experience of pain" are delayed until between 32-34 weeks. (oneofus.eu)
- Babies have been known to survive at 22 weeks and earlier, although 23 weeks is generally considered the threshold of viability in the United States, where there exists superior neonatal technology. (operationrescue.org)
- At 24 weeks, the viability of healthy babies born to healthy mothers is undeniable in the medical community worldwide. (operationrescue.org)
- Kansas law implies that each case be individually reviewed and tested for viability beginning at 22 weeks gestation. (operationrescue.org)
- According to that date, Shaye would have been 25 weeks 5 days along, well past the 22 weeks when viability must be determined under Kansas law. (operationrescue.org)
- Medical science has advanced the time of fetal viability to approximately 24 weeks. (ontheissues.org)
- Fetal viability is typically between 22 and 24 weeks. (wskg.org)
- Alabama women would likely lose their right to pre-viability abortion access at or after 15 weeks," he wrote. (ajc.com)
- Under those cases, states were prohibited from banning abortion prior to fetal viability, around 23 weeks. (wjbf.com)
- They could have added weeks in there for viability," said Mehek Cooke, a lawyer working with the opposition campaign, Protect Women Ohio. (kxan.com)
Heartbeat1
- It also allows private citizens to sue anyone involved in helping someone get an abortion after a fetal heartbeat can be detected. (nhpr.org)
Umbilical1
- Normal fetal growth and umbilical artery Doppler waveforms have been described as being associated with perinatal survival. (medscape.com)
Uterus4
- Fetal viability is the ability of a human fetus to survive outside the uterus. (wikipedia.org)
- Viability, as the word has been used in the United States constitutional law since Roe v. Wade, is the potential of the fetus to survive outside the uterus after birth, natural or induced, when supported by up-to-date medicine. (wikipedia.org)
- According to Websters Encyclopedic Unabridged Dictionary of the English Language, viability of a fetus means having reached such a stage of development as to be capable of living, under normal conditions, outside the uterus. (wikipedia.org)
- The original language from the amendment's backers defined fetal viability as the fetus having "a significant likelihood of survival outside the uterus with reasonable measures. (kxan.com)
Preterm1
- We sought to characterise the bacterial and fungal stool flora of preterm neonates and organism viability and evaluate any associations with NEC and sepsis. (bmj.com)
Oxidative stress1
- Carbon dioxide is known to contribute to oxidative stress, which the researchers suggested would hinder fetal development. (newstarget.com)
Amendment6
- The proposed amendment would declare a fundamental right to abortion until fetal viability, or when needed to protect the life or health of the pregnant patient. (latimes.com)
- But the constitutional amendment outlined in Proposition 1 doesn't contain the word "viability. (californiahealthline.org)
- But in various committee hearings, supporters at times seemed confused by the language of their own bill and scrambled to answer definitively when asked whether the amendment would preserve the viability limit or discard it. (californiahealthline.org)
- But physicians involved in drafting the amendment, like Dr. Pratima Gupta , said no mistake was made: The word viability was left out on purpose. (californiahealthline.org)
- But critics say it would actually expand abortion rights, because the amendment ignores the concept of fetal viability. (wvxu.org)
- The text of the amendment explicitly states that "abortion may be prohibited after fetal viability. (nationalrighttolifenews.org)
Courts1
- In response, the courts have determined that the viability standard has replaced the original trimester formulation of Roe. (ontheissues.org)
Largely2
- Fetal viability depends largely on the fetal organ maturity, and environmental conditions. (wikipedia.org)
- Today, the Guttmacher Institute reports that more than half of American women live in states whose laws are considered hostile to abortion , largely as a result of these intrusions on pre-viability abortion access. (leaps.org)
Health5
- Sonogram images, sworn statements show that Women's Health Care Services intentionally underestimates fetal age and viability to avoid compliance with Kansas law. (operationrescue.org)
- The framework of viability remains central to the country's abortion law today, even as some states have passed laws in the name of protecting women's health that significantly undermine Roe . (leaps.org)
- Nevertheless, the viability framework stands: while states can pass pre-viability abortion restrictions that (ostensibly) protect the health of the woman or that strike some kind a balance between women's rights and fetal life, it is only after viability that they can completely favor fetal life over the rights of the woman (with limited exceptions when the woman's life is threatened). (leaps.org)
- c) For the stage subsequent to viability the State, in promoting its interest in the potentiality of human life, may, if it chooses, regulate, and even proscribe, abortion except where necessary, in appropriate medical judgment, for the preservation of the life or health of the mother. (cornell.edu)
- But - and these are two very big buts - it also says (1) that physicians may determine viability on a "case-by-case basis," and (2) that there is a right to abortion after viability until birth to protect "health" that is not limited to physical health. (nationalrighttolifenews.org)
Physicians1
- The rationale offered that physicians have willy-nilly ability to define viability as anything they want is inaccurate. (kxan.com)
Neural1
- Anyone willing to make absolute statements regarding fetal, infant or adult neural development and processing is a brave person," Paschall said, adding that "the complexities of the brain defy absolute explanation. (oneofus.eu)
19732
- Wolfe v. Isbell, 291 Ala. 327, 329 (Ala. 1973)] Various jurisdictions have different legal definitions of viability. (wikipedia.org)
- Viability has long been a controversial concept, plaguing ethicists on both sides of the abortion debate since it was embedded in the Roe v. Wade decision in 1973. (californiahealthline.org)
Evaluate1
- Therefore, this work aimed to evaluate the viability of ADMSCs cryopreserved with the combination of L-proline and trehalose over up to 90 days. (bvsalud.org)
Growth1
- In the reproductive performance cohort, littering indices, F2 viability, and growth were assessed until PND 28. (nih.gov)
Unborn3
- That stage of fetal development when the life of the unborn child may be continued indefinitely outside the womb by natural or artificial life-support systems. (wikipedia.org)
- Paschall's experience butts up against another theory offered by fetal pain skeptics, who argue that the unborn fetus is immersed in a mix of fluids that chemically induce sleep, meaning that even if the brain wiring were in place, the fetus will still be oblivious. (oneofus.eu)
- A majority of justices noted that "abortion is fundamentally different, as both Roe and Casey acknowledged, because it destroys what those decisions called 'fetal life' and what the law now before us describes as an 'unborn human being. (jonathanturley.org)
Specialist1
- Consultant Specialist in Fetal Medicine in Kent, close to London. (020.co.uk)
Likelihood1
- For purposes of abortion regulation, viability is reached when, in the judgement of the attending physician on the particular facts of the case before her, there is a reasonable likelihood of the fetuses' sustained survival outside the womb, with or without artificial support. (wikipedia.org)
Life4
- Viability is defined by law as when a baby can survive for an indefinite period outside the womb with natural or artificial life-supportive measures. (operationrescue.org)
- Once viability is reached, however, states have a 'compelling interest' in protecting fetal life. (leaps.org)
- I'm extremely well aware that there are many anti-abortionists for whom this term is hideously inappropriate, but there are also a lot of anti-abortionists who genuinely hold that position because they care about fetal life, and I was one of them. (freethoughtblogs.com)
- The Supreme Court justices wrote that a woman's right to privacy was protected only up to viability - the point when a fetus is capable of "meaningful life outside the mother's womb. (californiahealthline.org)
Mice1
- Oral, 90- and decrements in fetal/pup body weights following exposures to day exposures of rats and mice to NMP result in decrements in NMP vapor. (cdc.gov)
Pregnant women1
- Surgical exposures of pregnant women to anesthetics resulted in a 57 percent fetal loss in women exposed during the first trimester, but no increase in congenital defects among the offspring. (cdc.gov)
Point1
- end point is a decrease in fetal/pup body weights observed after oral, dermal, and inhalation exposures of dams to NMP. (cdc.gov)
Legal1
- Viability has always been a slippery notion on which to pin legal rights. (leaps.org)
Survive1
- Viability-the potential for a fetus to survive outside the womb-is a core dividing line in American law. (leaps.org)
Development1
- Lifespan Development - Fetal Age of Viability Stage. (powershow.com)
Question1
- As ever, the politics of abortion lurk directly behind the question of fetal pain. (oneofus.eu)
Stage1
- Fetal Age of Viability Stage. (powershow.com)
Birth1
- The ductus arteriosus is a small fetal structure that connects two large arteries (aorta and pulmonary) but becomes pathological when it is maintained after birth. (bvsalud.org)
Pain2
- Abortion activists derided studies and expert testimony confirming fetal pain. (oneofus.eu)
- They thus are right in the target zone of fetal pain legislation. (oneofus.eu)
Exists1
- Viability exists as a function of biomedical and technological capacities, which are different in different parts of the world. (wikipedia.org)