No data available that match "Fetal Diseases"



*  AHA Issues Fetal Heart Disease Guidance | Medpage Today
Heart Association has released a scientific statement that addresses the diagnosis and treatment of fetal cardiac disease. ... That includes a detailed discussion of the fetal echocardiogram -- the main tool for evaluating fetal cardiac disease -- and ... Source Reference: Donofrio M, et al "Diagnosis and treatment of fetal cardiac disease: a scientific statement from the American ... The authors also discussed the benefits of being able to diagnose fetal cardiac disease and initiate management before delivery ...
  https://www.medpagetoday.com/cardiology/prevention/45425
*  METHODS FOR THE DIAGNOSIS OF FETAL DISEASE - Patent application
The methods disclosed herein use the methylation status of fetal DNA to isolate fetal DNA from maternal DNA. Once the fetal DNA ... Patent application title: METHODS FOR THE DIAGNOSIS OF FETAL DISEASE. Inventors: David G. Peters (Pittsburgh, PA, US) Tianjiao ... Methods for the diagnosis of fetal disease. Top Inventors for class "Combinatorial chemistry technology: method, library, ... 15. The method of claim 1, wherein the fetal aneuploidy is a trisomy 18. 16. The method of claim 1, wherein the fetal ...
  http://www.patentsencyclopedia.com/app/20120065076
*  Fetal Health Foundation Awards $50,000 Research Grant to Further Study into Fetal Pulmonary Disease
The Fetal Health Foundation (FHF) has named Dr. Deprest of the Katholieke Universiteit of Leuven (Belgium) and the University ... Fetal Health Foundation Awards $50,000 Research Grant to Further Study into Fetal Pulmonary Disease ... Fetal Health Foundation. From this industry Education and Training Government Lifestyle and Leisure Medical and Healthcare ... Diagnosed with fetal hydrops, a condition caused when abnormal amounts of fluid build in two or more body areas of a fetus or ...
  http://www.marketwired.com/press-release/fetal-health-foundation-awards-50000-research-grant-further-study-into-fetal-pulmonary-2174202.htm
*  Recent Articles | Fetal Brain And Disease/Medicine | The Scientist Magazine®| Page 55
Single-cell genome analyses reveal the amount of mutations a human brain cell will collect from its fetal beginnings until ... Particular microbes in the colons of HIV patients may worsen disease progression. ... tags: fetal brain x disease/medicine x The Scientist. » fetal brain and disease/medicine ...
  https://www.the-scientist.com/?articles.list/tagNo/1166,6/tags/fetal-brain,disease-medicine/pageNo/55/
*  The global burden of Rh disease | ADC Fetal & Neonatal Edition
Of the survivors, 30% had severe disease almost certainly fatal without treatment, while an additional 30% had moderate disease ... The natural history of the disease has not been described in recent literature. Walker,1 in 1971, reviewed a series of cases ... Therefore, it can be estimated that approximately 50% of children with untreated haemolytic disease of the newborn (HDN) will ... prevention of Rh disease was instituted using postpartum injections of anti-Rh (anti-D) γ globulin; this has been proven to be ...
  http://fn.bmj.com/content/96/2/F84
*  Apoptosis in neural development and disease | ADC Fetal & Neonatal Edition
Apoptosis in nervous system injury and disease. Although apoptosis is involved in a number of diseases of the nervous system,40 ... In Parkinson's disease the death of dopaminergic neurons in the substantia nigra has been shown to occur by apoptosis and can ... 1996) Huntington's disease: translating a CAG repeat into a pathogenic mechanism. Curr Opin Neurobiol 6:638-643. ... INFECTIOUS DISEASE. Apoptosis may have a role in HIV encephalopathy. In the brain the virus replicates primarily in microglia ...
  http://fn.bmj.com/content/77/3/F165
*  Metabolic disease: maternal diet influences fetal fatty liver | Disease Models & Mechanisms
Metabolic disease: maternal diet influences fetal fatty liver Message Subject (Your Name) has sent you a message from Disease ... 2009). Maternal high-fat diet triggers lipotoxicity in the fetal livers of nonhuman primates. J Clin. Invest. 119, 323- 335.. ... Non-alcoholic fatty liver disease (NAFLD) is a result of lipid accumulation and inflammation in hepatic cells. It is linked to ... The lipotoxicity seen in fetal livers persists into the postnatal period, illustrating that exposure to a high-fat diet during ...
  http://dmm.biologists.org/content/2/3-4/94.4
*  Fetal programming of disease risk to next generation depends on paren... ( Overexposure to stress hormones in t...)
This has led to the concept of fetal programming suggesting that the...,Fetal,programming,of,disease,risk,to,next,generation, ... Hurricanes Linked to Raised Fetal Distress Risk. 9. Study finds changes in fetal epigenetics throughout pregnancy. 10. Fetal ... Fetal Surgery Could Boost Outcomes in Severe Spina Bifida. 6. Figuring out fetal alcohol syndrome in fruit flies. 7. AIUM ... Society for Maternal-Fetal Medicine commends FDA on makena announcement. 3. Study finds that electronic fetal heart rate ...
  http://www.bio-medicine.org/medicine-news-1/Fetal-programming-of-disease-risk-to-next-generation-depends-on-parental-gender-82566-1/
*  Liver disease in pregnancy and fetal fatty acid oxidation defects.
Maternal-Fetal Exchange. Mitochondria, Liver / metabolism. Oxidation-Reduction. Phenotype. Pregnancy. Pregnancy Complications ... Many women who carried LCHAD-deficient fetuses developed maternal liver disease. Over the past few years, we and others have ... The likely mechanisms for the genotype-phenotype correlations in pediatric LCHAD deficiency and the fetal-maternal interaction ... made significant progress in understanding the molecular basis for this fetal-maternal interaction. Here, we review the studies ...
  http://www.biomedsearch.com/nih/Liver-disease-in-pregnancy-fetal/11001809.html
*  Fetal Origins of Cardiovascular and Lung Disease (Hardback) - Routledge
... and chronic lung disease originate through adaptations to the intrauterine environment. These new findings suggest that… ... and experimental evidence that cardiovascular disease, Type 2 diabetes, ...
  https://www.routledge.com/Fetal-Origins-of-Cardiovascular-and-Lung-Disease/Barker/p/book/9780824703912
*  Fetal Hemolytic Disease - Online Obstetrics Course | Lecturio
Fetal Hemolytic Disease' and prepare for your medical exams with high-yield content ✓ & quiz questions ✓ now! ... Hemolytic Disease of the Newborn (HDN) - Causes and Symptoms Fetal hemolytic disease (FHD), also known as hemolytic disease of ... The lecture Fetal Hemolytic Disease by Veronica Gillispie, MD, FACOG is from the course Antenatal Care. ...
  https://www.lecturio.com/medical-courses/fetal-hemolytic-disease.lecture
*  Efficacy of Vorinostat to Induce Fetal Hemoglobin in Sickle Cell Disease - Tabular View - ClinicalTrials.gov
Efficacy of Vorinostat to Induce Fetal Hemoglobin in Sickle Cell Disease. The safety and scientific validity of this study is ... Efficacy of Vorinostat to Induce Fetal Hemoglobin in Sickle Cell Disease. Official Title ICMJE A Phase II Pharmacodynamic ... To describe the dose-response characteristics of vorinostat in inducing fetal hemoglobin in sickle cell disease [ Time Frame: 2 ... To describe the dose-response characteristics of vorinostat in inducing fetal hemoglobin in sickle cell disease. ...
  https://clinicaltrials.gov/ct2/show/record/NCT01000155
*  Studies of twins: what can they tell us about the fetal origins of adult disease? - Morley - 2005 - Paediatric and Perinatal...
The fetal origin of adult disease: from sceptic to convert. Paediatric and Perinatal Epidemiology 2000; 14: 192-193.. Direct ... Fetal origins of adult disease? Clinical and Experimental Pharmacology and Physiology 2001; 28: 962-966.. Direct Link: ... Fetal origins of adult disease: epidemiology and mechanisms. Journal of Clinical Pathology 2000; 53: 822-828.. *CrossRef, ... Ischaemic heart disease and low birth weight: a test of the fetal-origins hypothesis from the Swedish Twin Registry. Lancet ...
  http://onlinelibrary.wiley.com/doi/10.1111/j.1365-3016.2005.00608.x/references
*  Fetal and infant markers of adult heart diseases | Heart
Hormonal evidence related to fetal growth and later heart disease risk. Fetal growth is also affected by several hormones, ... Forsén T. Early growth and adult disease. Programming of coronary heart disease, Type 2 diabetes and hypertension by fetal and ... A key concept in the "fetal origin hypothesis" is fetal undernutrition, and its relation with adult diseases. The human ... A review of the role of fetal glucocorticoid exposure in the programming of adulthood disease. During fetal development ...
  http://heart.bmj.com/content/84/2/219
*  Role of hyperkalaemia in experimental fetal asphyxia. | Archives of Disease in Childhood
Role of hyperkalaemia in experimental fetal asphyxia. Message subject: (Your Name) has forwarded a page to you from Archives of ... Disease in Childhood Message body: (Your Name) thought you would like to see this page from the Archives of Disease in ...
  http://adc.bmj.com/content/43/232/747.4.share
*  IS-024 Fetal Cardiac Interventions | Archives of Disease in Childhood
Intervention in fetal PAIVS is technically more challenging. In our centre 12 attempts have been performed in 10 fetuses all ... In fetal CAS the left ventricle (LV) dilates, shortening decreases and endocardial fibroelastosis develops. The most important ... Fetal cardiac interventions are currently performed for critical aortic stenosis (CAS), pulmonary atresia intact septum (PA/IVS ... Intact atrial septum in fetal HLHS has to be treated with transseptal stent placement to prevent re-occlusion. Results however ...
  http://adc.bmj.com/content/99/Suppl_2/A8.3
*  Fetal origin of childhood disease: Intrauterine growth restriction in term infants and risk for hypertension at 6 years of age ...
... Shankaran, S., Das, A., Bauer, C. R., Bada, H., Lester, B., Wright, L., ... Poole, W. (2006). Fetal origin of childhood disease ... which may be a marker for adult cardiovascular disease. ,br,,br,,br, ...
  https://www.rti.org/publication/fetal-origin-childhood-disease-intrauterine-growth-restriction-term-infants-and-risk
*  FDA-Approved Fetal Stem-Cell Treatment for Eye Disease Being Tested for Spinal Injuries
Fetal Tissue Strategy. Stem cells are undifferentiated, primitive cells that have the ability both to multiply and to ... Not all fetal tissue is derived from morally problematic sources, Vinnedge said. "Parents could donate tissue from a miscarried ... StemCells Inc.'s approach is to rely on fetal stem cells because they have already developed to the point when they will only ... And while you state that it has done nothing but control the disease, that is not accurate. The treatment has been shown to ...
  http://www.ncregister.com/daily-news/fda-approved-fetal-stem-cell-treatment-for-eye-disease-being-tested-for-spi
*  Efficacy of Routine Fetal Ultrasound Screening for Congenital Heart Disease in Normal Pregnancy | Circulation
Efficacy of Routine Fetal Ultrasound Screening for Congenital Heart Disease in Normal Pregnancy. E. Buskens, D.E. Grobbee, I.M. ... Efficacy of Routine Fetal Ultrasound Screening for Congenital Heart Disease in Normal Pregnancy ... Efficacy of Routine Fetal Ultrasound Screening for Congenital Heart Disease in Normal Pregnancy ... Efficacy of Routine Fetal Ultrasound Screening for Congenital Heart Disease in Normal Pregnancy ...
  http://circ.ahajournals.org/content/94/1/67.short
*  Immunochemical estimation of some proteins in Nigerian paired maternal and fetal blood. | Archives of Disease in Childhood
Immunochemical estimation of some proteins in Nigerian paired maternal and fetal blood. ... Immunochemical estimation of some proteins in Nigerian paired maternal and fetal blood. ...
  http://adc.bmj.com/content/43/227/42
*  Symptoms causes treatment of disease: Fetal Alcohol Syndrome - Symptoms, Statistics, Pictures, Facts, Treatment
... disease grave s disease Grave's Disease graves disease and pregnancy Graves Disease Causes Graves Disease Diet Graves Disease ... Celiac Disease celiac disease diet celiac disease in children celiac disease symptoms celiac disease test celiac s disease ... disease life expectancy fabry disease prognosis fabry disease symptoms fabry disease treatment fabry s disease fabrys disease ... Fibroids Fifth Disease during Pregnancy Fifth Disease in Adults Fifth Disease Pictures Fifth Disease Symptoms Fifth Disease ...
  http://symptoms-causes-treatment.blogspot.com/2013/10/fetal-alcohol-syndrome-symptoms.html
*  Fetal macrosomia in developing countries | Archives of Disease in Childhood
The prevalence of fetal macrosomia in developed countries has increased by some 15-25% in recent decades, an increase largely ... Risk factors for macrosomia include male fetal sex, high parity, maternal age, and height, post-term pregnancy, and pre- ...
  http://adc.bmj.com/content/98/6/461
*  Fetal Programming and Disease 1 | Abbott Nutrition Health Institute
This course describes the hypothesis that an insult to the embryo or fetus during gestation can alter the course of fetal ... Nutrition and the Fetal Programming of Chronic Disease - Part 1. Program Date: June 2011 ... The content of this program is based on the concept of fetal programming and the impact that nutrition has on the infant's ... Describe the hypothesis that an insult to the embryo or fetus during gestation can alter the course of fetal development. ...
  https://anhi.org/education/course-catalog/92EDB3456F06411B91BBD1A98826CC21
*  Accutane, Fetal Effects of - Diseases and Condition - 2662
... and 1000's of other diseases, symptoms, drugs, doctors, specialists, and clinics in our trustw ... Genetic and Rare Diseases (GARD) Information Center PO Box 8126. Gaithersburg, MD 20898-8126. Tel: (301)251-4925. Fax: (301)251 ... Define Common Diseases. Welcome to WebHealthNetwork, here you can find information, definitaions and treatement options for ... most common diseases, sicknesses, illnesses and medical conditions. Find what diseases you have quick and now. ...
  http://webhealthnetwork.com/disease/9-2662/accutane-fetal-effects-of
*  Massive increase of foetal abdominal circumference due to hereditary polycystic kidney disease
Autosomal recessive polycystic kidney disease (ARPKD) is a rare condition with a poor prognosis. We report on a 30-year-old ... Massive increase of foetal abdominal circumference due to hereditary polycystic kidney disease. ... Fetal Macrosomia / ultrasonography*. Humans. Infant, Newborn. Male. Polycystic Kidney, Autosomal Recessive / ultrasonography*. ... Foetal digitalisation because of heart insufficiency and prophylactic lung maturation was started. In the further course, ...
  http://www.biomedsearch.com/nih/Massive-Increase-Foetal-Abdominal-Circumference/20574939.html

No data available that match "Fetal Diseases"



(1/1979) Increased phosphoglycerate kinase in the brains of patients with Down's syndrome but not with Alzheimer's disease.

Impaired glucose metabolism in Down's syndrome (DS) has been well-documented in vivo, although information on the underlying biochemical defect is limited and no biochemical studies on glucose handling enzymes have been carried out in the brain. Through gene hunting in fetal DS brain we found an overexpressed sequence homologous to the phosphoglycerate kinase (PGK) gene. This finding was studied further by investigating the activity levels of this key enzyme of carbohydrate metabolism in the brains of patients with DS. PGK activity was determined in five brain regions of nine patients with DS, nine patients with Alzheimer's disease and 14 controls. PGK activity was significantly elevated in the frontal, occipital and temporal lobe and in the cerebellum of patients with DS. PGK activity in corresponding brain regions of patients with Alzheimer's disease was comparable with controls. We conclude that our findings complement previously published data on impaired brain glucose metabolism in DS evaluated by positron emission tomography in clinical studies. Furthermore, we show that in DS, impaired glucose metabolism, represented by increased PGK activity, is a specific finding rather than a secondary phenomenon simply due to neurodegeneration or atrophy. These observations are also supported by data from subtractive hybridization, showing overexpressed PGK in DS brains at the transcriptional level early in life.  (+info)

(2/1979) Can transvaginal fetal biometry be considered a useful tool for early detection of skeletal dysplasias in high-risk patients?

OBJECTIVE: To evaluate the possibility of an early diagnosis of skeletal dysplasias in high-risk patients. METHODS: A total of 149 consecutive, uncomplicated singleton pregnancies at 9-13 weeks' amenorrhea, with certain menstrual history and regular cycles, were investigated with transvaginal ultrasound to establish the relationship between femur length and menstrual age, biparietal diameter and crown-rump length, using a polynomial regression model. A further eight patients with previous skeletal dysplasias in a total of 13 pregnancies were evaluated with serial examinations every 2 weeks from 10-11 weeks. RESULTS: A significant correlation between femur length and crown-rump length and biparietal diameter was found, whereas none was observed between femur length and menstrual age. Of the five cases with skeletal dysplasias, only two (one with recurrent osteogenesis imperfecta and one with recurrent achondrogenesis) were diagnosed in the first trimester. CONCLUSIONS: An early evaluation of fetal morphology in conjunction with the use of biometric charts of femur length against crown-rump length and femur length against biparietal diameter may be crucial for early diagnosis of severe skeletal dysplasias. By contrast, in less severe cases, biometric evaluation appears to be of no value for diagnosis.  (+info)

(3/1979) Comparison of prenatal ultrasound and postmortem findings in fetuses and infants with congenital heart defects.

OBJECTIVE: Detection of congenital heart defects by prenatal ultrasound examination has been one of the great challenges since the investigation for fetal anomalies became part of the routine fetal examination. This prospective study was designed to evaluate the concordance of prenatal ultrasound findings with autopsy examination in a population consisting of both referred women and non-selected pregnant women. DESIGN: Criteria for inclusion were an ultrasound examination at the National Center for Fetal Medicine and an autopsy performed during the years 1985-94. Results from the ultrasound and autopsy examinations were systematized into categories depending on the degree of concordance. RESULTS: Of 408 infants and fetuses with developmental anomalies, 106 (26%) had congenital heart defects. In 63 (59%) of these 106 cases, the heart defect was the principal reason for the termination of pregnancy or the cause of death. Excluding five cases with a secundum atrial septal defect, there was complete agreement between the ultrasound examination and the autopsy findings in 74 (73%) of 101 cases. In 18 cases, there were minor discrepancies between ultrasound and autopsy findings. The main diagnosis was thus correct in 92 cases (91%). From the first time period (1985-89) to the second (1990-94), the detection rate of all heart defects increased from 48% to 82%. CONCLUSION: This study confirms a good correlation between ultrasound and autopsy diagnoses in fetuses and infants with congenital heart defects. A significant improvement in the detection of heart defects occurred from the first time period to the second and was probably due to increased experience and technical advances.  (+info)

(4/1979) Diagnosis of twin reversed arterial perfusion sequence in the first trimester by transvaginal color Doppler ultrasound.

A case of twin reversed arterial perfusion (TRAP) sequence was diagnosed at 12 weeks' gestation using transvaginal color Doppler ultrasound, which demonstrated the presence of retrograde perfusion in the umbilical artery of the abnormal twin. Ultrasound imaging showed a monochorionic-diamniotic twin pregnancy with an inappropriately grown second twin, the morphological evaluation of which revealed an abnormal cephalic pole with acrania, diffuse subcutaneous edema and the presence of cardiac activity in an abnormal heart with a single chamber.  (+info)

(5/1979) Amylopectinosis in fetal and neonatal Quarter Horses.

Three Quarter Horses, a stillborn filly (horse No. 1), a female fetus aborted at approximately 6 months of gestation (horse No. 2), and a 1-month-old colt that had been weak at birth (horse No. 3), had myopathy characterized histologically by large spherical or ovoid inclusions in skeletal and cardiac myofibers. Smaller inclusions were also found in brain and spinal cord and in some cells of all other tissues examined. These inclusions were basophilic, red-purple after staining with periodic acid-Schiff (both before and after digestion with diastase), and moderately dark blue after staining with toluidine blue. The inclusions did not react when stained with Congo red. Staining with iodine ranged from pale blue to black. Their ultrastructural appearance varied from amorphous to somewhat filamentous. On the basis of staining characteristics and diastase resistance, we concluded that these inclusions contained amylopectin. A distinctly different kind of inclusion material was also present in skeletal muscle and tongue of horse Nos. 1 and 3. These inclusions were crystalline with a sharply defined ultrastructural periodicity. The crystals were eosinophilic and very dark blue when stained with toluidine blue but did not stain with iodine. Crystals sometimes occurred freely within the myofibers but more often were encased by deposits of amylopectin. This combination of histologic and ultrastructural features characterizes a previously unreported storage disease in fetal and neonatal Quarter Horses, with findings similar to those of glycogen storage disease type IV. We speculate that a severe inherited loss of glycogen brancher enzyme activity may be responsible for these findings. The relation of amylopectinosis to the death of the foals is unknown.  (+info)

(6/1979) Whence the arthrogrypotics?

During the course of a nation-wide survey of patients with bone and joint deformities, twenty-six individuals with arthrogryposis multiplex congenita, in the narrow and precise sense of the term, were investigated. No patient was more than twenty-four years of age. However, on a basis of the figures of population, it can be estimated that 21-0 +/- 6-5 older affected individuals should have been encountered. Furthermore, there was a relative excess of younger children. The series was reasonably unbiased, and as arthrogryposis is non-lethal the deficiency of affected adults is an anomalous finding. It is tentatively suggested that arthrogryposis might result from the intra-uterine influence of an unknown environmental agent which has been present in South Africa for only a limited period of time. Detection of this factor could be an important step in the prevention of the disease.  (+info)

(7/1979) Neurological morbidity after fetal supraventricular tachyarrhythmia.

BACKGROUND: Fetal tachyarrhythmia is a well-documented entity which, in the absence of pharmacological intervention, may lead to congestive heart failure, fetal hydrops and eventually fetal demise. The success rate of the implemented treatment is generally measured by survival and achievement of control of the arrhythmia. We report on the occurrence of associated cerebral damage in three patients with fetal tachycardia. METHODS: We describe three patients with a history of fetal supraventricular tachyarrhythmia who developed cerebral complications in utero. RESULTS: Two patients had cerebral hypoxic-ischemic lesions and one had hemorrhagic lesions present at birth. They had developed severe congestive heart failure and fetal hydrops secondary to fetal tachyarrhythmia, and there were no other obvious causes for the cerebral pathology. Two of these patients were referred to us antenatally. Therapy was instituted and resulted in control of the tachycardia and resolution of hydrops. The third patient was referred to our clinic shortly after birth because of severe circulatory problems secondary to fetal tachyarrhythmia. CONCLUSION: From these observations, we believe that a fetus with tachyarrhythmia and subsequent hydrops is at increased risk for the development of cerebral complications, due to the circulatory disturbances and sudden changes in heart rate which may lead to fluctuations in cerebral perfusion. This would imply that it is of the utmost importance to aim at immediate and complete control of the heart rate in the treatment of fetal tachyarrhythmia.  (+info)

(8/1979) Trisomy 10: first-trimester features on ultrasound, fetoscopy and postmortem of a case associated with increased nuchal translucency.

We report a case of the prenatal diagnosis of trisomy 10 in a fetus presenting with an increased nuchal translucency thickness (5 mm) on a routine first-trimester anomaly scan at 12 weeks' gestation. Multiple abnormalities were diagnosed by ultrasound and fetoscopy. Karyotyping on chorionic villus sampling led to the diagnosis of homogeneous trisomy 10 which was confirmed by in situ hybridization on fetal tissue samples. Postmortem examination confirmed major anatomical malformations, including facial cleft, arthrogryposis of the upper and lower limbs and bilateral diaphragmatic hernia, and also revealed hypoplastic lungs, right renal agenesis and a complex cardiac malformation. Trisomy 10 is an uncommon chromosomal abnormality that is likely to be associated with increased fetal nuchal translucency. This case also emphasizes the value of a detailed anomaly scan in high-risk patients in the first trimester of pregnancy.  (+info)



  • intrauterine
  • Based in Littleton, Colo., the Fetal Health Foundation administers the Brianna Marie Memorial Research Grant and is an international leader in supporting families and medical treatment centers dealing with intrauterine fetal syndromes. (marketwired.com)
  • coronary heart d
  • For example, in the mid 1980s Rose pointed out that the well established risk factors for coronary heart disease (CHD)-cigarette smoking, high serum cholesterol, and high blood pressure-have a limited ability to predict disease risk in adults. (bmj.com)
  • In 1986, Barker published findings proposing a direct link between prenatal nutrition and late-onset coronary heart disease. (wikipedia.org)
  • adult disease
  • Changes in fetal growth pattern have been related to adult disease risk, 1 and there are many theories about the underlying mechanisms affecting cell division during critical periods of tissue development. (bmj.com)
  • The critical periods vary according to the tissue in question, and that is why there have been attempts to explore the timing of exposure in order to predict more specifically the adult disease risk. (bmj.com)
  • and thirdly the specific problems in longitudinal studies which explore these factors and adult disease risk. (bmj.com)
  • He had noticed that the poorest areas of England were the same areas with the highest rates of heart disease, unearthing the predictive relationship between low birth weight and adult disease. (wikipedia.org)
  • fetuses
  • Many women who carried LCHAD-deficient fetuses developed maternal liver disease. (biomedsearch.com)
  • In his 1995 encyclical Evangelium Vitae , John Paul said, "This moral condemnation also regards procedures that exploit living human embryos and fetuses - sometimes 'produced' for this purpose by in vitro fertilization - either to be used as 'biological material' or as providers or organs or tissue for transplants in the treatment of certain diseases. (ncregister.com)
  • StemCells's patented HuCNS-SC cells are derived from the central nervous system of fetuses and designed to treat diseases affecting all parts of the system, including the eyes. (ncregister.com)
  • The Fetal Treatment Center is also currently investigating determine whether steroids might be effective in helping fetuses with large microcystic Congenital cystic adenomatoid malformation (CCAM). (wikipedia.org)
  • infant
  • Debi Vinnedge, president of Children of God for Life, a Florida organization devoted to fighting the use of fetal-derived products in both the food and drug industries, said it was a long-established practice in biological research to term all non-embryonic cells, whether from fetal, infant or adult stages, as "adult" because they share important characteristics that set them apart from embryonic cells. (ncregister.com)
  • cardiac
  • The statement notes that fetal cardiac medicine has evolved considerably over the past 2 decades, predominantly in response to advances in imaging technology and innovations in therapies. (medpagetoday.com)
  • To create the statement, Donofrio and colleagues reviewed literature covering the diagnosis of congenital heart disease and arrhythmias, the assessment of cardiac function and the rest of the cardiovascular system, and the range of treatments available. (medpagetoday.com)
  • The authors also discussed the benefits of being able to diagnose fetal cardiac disease and initiate management before delivery, which allows counseling of the parents and prediction of the clinical course of disease in preparation for delivery. (medpagetoday.com)
  • Fetal cardiac interventions are currently performed for critical aortic stenosis (CAS), pulmonary atresia intact septum (PA/IVS) and closed atrial septum in hypoplastic left heart syndrome (HLHS). (bmj.com)
  • alcohol syndrome
  • As perhaps the most well-known fetal risk, It wasn't until 1973 that fetal alcohol syndrome was first formally diagnosed, and not until 1989 that the United States government began requiring warning labels directed at pregnant women to be in place on all alcoholic beverages for sale. (wikipedia.org)
  • Efficacy
  • To determine the efficacy of vorinostat when administered orally in inducing a 4% absolute increase or a 100% increase in fetal hemoglobin levels in subjects with severe sickle cell disease who have failed prior therapy. (clinicaltrials.gov)
  • syndrome
  • A genome-wide screening and linkage analysis assigned the disease locus of lethal congenital contracture syndrome, one of 40 Finnish heritage diseases, to a defined region of 9q34, where the GLE1 gene is located. (wikipedia.org)
  • congenital heart d
  • A total of 80 cases of congenital malformations were diagnosed during the study: 44 cases of congenital heart disease, 40 cases of noncardiac malformations, and a combination of the two in 4 cases. (ahajournals.org)
  • Phenotype
  • The information that enters offspring phenotype during early development mirror the mother's own developmental experience and the quality of the environment during her own maturation rather than predicting the possible future environment of the offspring Many human diseases in adulthood are related to growth patterns during early life, determining early-life nutrition as the underlying mechanism. (wikipedia.org)
  • mutations
  • Single-cell genome analyses reveal the amount of mutations a human brain cell will collect from its fetal beginnings until death. (the-scientist.com)
  • arthrogryposis
  • Lethal arthrogryposis with anterior horn cell disease (LAAHD) is an autosomal recessive genetic disorder characterized by reduced mobility of the foetus and early death. (wikipedia.org)
  • Lethal arthrogryposis with anterior horn cell disease Online Mendelian Inheritance in Man (OMIM) 255310 Norio R (2003). (wikipedia.org)
  • wherein
  • 5. The method of claim 1, wherein selectively purifying fetal DNA from a maternal biological sample using the methylation status of a CpG containing genomic sequence comprises the use of a microarray. (patentsencyclopedia.com)
  • 6. The method of claim 1, wherein selectively purifying fetal DNA from a maternal biological sample using the methylation status of a CpG containing genomic sequence comprises the use of a restriction enzyme that differentially cleaves methylated or unmethylated DNA. (patentsencyclopedia.com)
  • Causes
  • Sickle Cell Disease (SCD) is a hereditary anemia that causes the red blood cells to change their shape from a round and doughnut-like shape to a half-moon/crescent, or sickled shape. (clinicaltrials.gov)
  • It causes a wide range of clinical disorders, ranging from lethal neonatal disease to adult-onset neurodegenerative disorders. (wikipedia.org)
  • He is best known for his work Domestic Medicine: or, a Treatise on the Prevention and Cure of Diseases by Regimen and Simple Medicines, which provided laypeople with detailed descriptions of the causes and prevention of diseases. (wikipedia.org)
  • Circulation
  • Among these antibodies are some which attack antigens on the red blood cells in the fetal circulation, breaking down and destroying the cells (hemolysis). (wikipedia.org)
  • Risk
  • Fetal programming of disease risk to next generation depends on paren. (bio-medicine.org)
  • This has led to the concept of fetal programming, suggesting that the environment experienced in the womb can affect development, resulting in an increased risk of later disease. (bio-medicine.org)
  • This increased disease risk can be passed to the next generation," Drake said. (bio-medicine.org)
  • This increased the likelihood of the baby rats having a low birth weight and increased their risk of developing diabetes and heart disease in later life, she said. (bio-medicine.org)
  • w3 However, lifestyle factors only explain part of the heart disease risk, which is why other reasons have been sought. (bmj.com)
  • w5 In the large international MONICA (monitoring trends and determinants in cardiovascular disease) project, w2 w4 only 25% of the variance in CHD mortality was explained by conventional risk factors. (bmj.com)
  • Conclusion In term infants, IUGR is linked to risk of hypertension in early childhood, which may be a marker for adult cardiovascular disease. (rti.org)
  • Women who have had pre-eclampsia are at increased risk of heart disease and stroke later in life. (wikipedia.org)
  • cardiovascular disease
  • 1 w1 It seems likely that the large geographic variations in cardiovascular disease (CVD) morbidity and mortality, w2 even though at least partly genetic in origin, are influenced by factors acting prenatally and in early life, or by a combination of factors present throughout the life course. (bmj.com)
  • lung
  • The funds awarded to Dr. Deprest's study will be used to target prevention of congenital diaphragmatic hernia (CDH), an anomaly that disturbs lung development during fetal life. (marketwired.com)
  • When humans are exposed to cadmium over a long period of time, kidney disease and lung disease can occur. (wikipedia.org)
  • Arsenic: When high amounts of arsenic is inhaled or ingested through coal ash waste, diseases such as bladder cancer, skin cancer, kidney cancer and lung cancer can develop. (wikipedia.org)
  • interventions
  • Regarding the study, which was funded by the U.K. Medical Research Council, Drake said, "It could help inform future research to find interventions that could prevent diseases such as diabetes and high blood pressure," Drake said. (bio-medicine.org)
  • heart
  • There is growing evidence of an increasingly complex and multifactorial aetiology of heart diseases. (bmj.com)
  • His findings were met with criticism, mainly because at the time heart disease was considered to be predominantly determined by lifestyle and genetic factors. (wikipedia.org)
  • Liver
  • In severe disease there may be red blood cell breakdown, a low blood platelet count, impaired liver function, kidney dysfunction, swelling, shortness of breath due to fluid in the lungs, or visual disturbances. (wikipedia.org)
  • severe
  • Of the survivors, 30% had severe disease almost certainly fatal without treatment, while an additional 30% had moderate disease which would manifest as severe hyperbilirubinaemia that untreated may result in brain damage and/or death. (bmj.com)
  • When the disease is moderate or severe, many erythroblasts (immature red blood cells) are present in the fetal blood, and so these forms of the disease can be called erythroblastosis fetalis (or erythroblastosis foetalis). (wikipedia.org)
  • The inwards spiral and especially the elbow contractures are less severe than in LCCS1 disease. (wikipedia.org)
  • Magnesium sulfate may be used to prevent eclampsia in those with severe disease. (wikipedia.org)
  • chronic
  • w4 This led to the lifestyle model in understanding the aetiology of chronic diseases, where the key issues are health behaviour and the interaction between genes and an adverse environment in adult life. (bmj.com)
  • These historical cohort studies 3-5 w7 w8 and evidence from animal experiments 1 w9 suggest that chronic diseases are biologically "programmed" in utero or in early infancy. (bmj.com)
  • life
  • However, LifeSite News, the Toronto-based pro-life news organization, dug into the firm's website to find "human neural stem cells" described more brutally as "fresh human fetal brain tissue. (ncregister.com)
  • Die Krankheiten der ersten Lebenstage, 1885 - Diseases of the first days of life. (wikipedia.org)
  • influences
  • An acquired characteristic is a non-heritable change in a function or structure of a living biotic material caused after birth by disease, injury, accident, deliberate modification, variation, repeated use, disuse, or misuse, or other environmental influences. (wikipedia.org)
  • When diseases are caused by environmental influences, such as iodine deficiency or lead poisoning, their resultant symptoms are unequivocally agreed to be acquired characteristics. (wikipedia.org)
  • autoimmune
  • Dysregulation of apoptosis can result in the persistence of mutated cells, leading to malformations, autoimmune disease, and cancer. (bmj.com)
  • It has proven successful in treating more than 70 kinds of cancers and autoimmune diseases such as multiple sclerosis. (ncregister.com)
  • medicine
  • Domestic Medicine also was one of the first texts not only to discuss potential cures to diseases, but also to emphasize prevention. (wikipedia.org)
  • neurodegenerative
  • On the other hand, inappropriate apoptosis resulting in the removal of healthy cells can occur in diseases such as infection, hypoxic-ischaemic injury, neurodegenerative or neuromuscular diseases, and AIDS. (bmj.com)
  • birth
  • This new research showed that although birth weight is reduced in the offspring of male or female rats that were exposed to dexamethasone during fetal development, this effect was more pronounced in the offspring of male rats exposed to excess glucocorticoids during development in the womb. (bio-medicine.org)
  • alternatively, it can be a harmful mechanism, when fetal conditions of plenitude or scarcity do not match the world of birth and the child has been physiologically predisposed to inhabit an environment where expected resources are drastically different from reality. (wikipedia.org)
  • treatment
  • Percent Fetal Hemoglobin (HbF%) Induction Success Rate [ Time Frame: HbF% was measured at baseline and weekly on treatment. (clinicaltrials.gov)
  • It has also striven to develop less invasive means of treatment such as fetendo and fetal image-guided surgery. (wikipedia.org)
  • Dr. Hanmin Lee M.D. is the current Director for the UCSF Fetal Treatment Center, replacing Harrison who is now Director Emeritus. (wikipedia.org)
  • Infectious
  • Infectious diseases, especially in the field of HIV infection. (wikipedia.org)
  • Established by Congress to combat a wide range of animal diseases-from infectious disease of swine to bovine pneumonia, Texas cattle fever to glanders-Smith worked under Daniel E. Salmon, a veterinarian and Chief of the BAI. (wikipedia.org)
  • This marked the first time that an arthropod had been definitively linked with the transmission of an infectious disease and presaged the eventual discovery of insects as important vectors in a number of diseases (see yellow fever, malaria). (wikipedia.org)
  • include
  • Now in its third year of administering and awarding grants for fetal health research, FHF expanded its scope to include research projects from international centers and combined funds to allocate $50,000 to the grant recipient in order to increase the impact of the grant. (marketwired.com)