Sweat Glands
Sebaceous Glands
Carcinoma, Skin Appendage
Sebum
Encyclopedias as Topic
Hair Follicle
Hair
Osteitis Deformans
Paget's Disease, Mammary
Paget Disease, Extramammary
Myositis, Inclusion Body
Carcinoma, Intraductal, Noninfiltrating
Mohs Surgery
Eccrine adenocarcinoma of the footpads in 2 cats. (1/65)
Adenocarcinoma of sweat glands of the footpads was diagnosed in 2 cats. Clinical signs included lameness and swelling of multiple digits. Pulmonary metastasis was detected in one case. Diagnosis was based on histopathological and immunohistochemical findings. Eccrine adenocarcinoma should be included in the differential diagnosis of footpads lesions in aged cats. (+info)Histo-physiology of the scent-marking glands of the penile pad, anal pouch, and the forefoot in the aardwolf (Proteles cristatus). (2/65)
The scentmarking glands of the anal pouch, penile pad, and the forefoot of the aardwolf (Proteles cristatus) were studied by histological, histochemical, immunohistochemical methods, and by electron microscopy. The morphological observations are correlated with eco-ethological aspects of this nocturnal animal. In all studied regions there was a superficial layer of holocrine sebaceous glands and a deeper layer of apocrine scent glands; these two types of glands apparently function in concert. Only in the forefoot were additional tubular glands, resembling eccrine sweat glands found, which may improve the frictional capacities of the paw, while apocrine and holocrine glands serve scent-marking functions of the forefoot. Penile pad and anal pouch are exclusively scent marking organs. The secretion modus of the apocrine glands is both via exocytosis and apocrine mechanism. Homogeneous apical, secretory granules, which contain glycoproteinaceous material, represent evidence for exocytosis. In the anal pouch, additional variably sized granules contain endogenous pigments which are probably responsible for the brownish coloration of the secretory product of the male animals. Variable heights of the glandular cells, frequent apical tall protrusions as well as pinched-off pieces of cytoplasm in the glandular tubules support the concept of an apocrine secretion in the scent glands. The immunohistochemical staining pattern of actin points to the involvement of actin filaments in the pinching-off process of the apical cell protrusion, which does not contain any cell organelles. The variable actin staining patterns suggest a dynamic process during which actin filaments form a ring or sheet at the basis of the pinching-off bleb. Proliferative and apoptotic phenomena show no preference for active and inactive glandular cells suggesting that replacement of cells occurs independently of the functional status of the glands. (+info)Function of human eccrine sweat glands during dynamic exercise and passive heat stress. (3/65)
The purpose of this study was to identify the pattern of change in the density of activated sweat glands (ASG) and sweat output per gland (SGO) during dynamic constant-workload exercise and passive heat stress. Eight male subjects (22.8 +/- 0.9 yr) exercised at a constant workload (117.5 +/- 4.8 W) and were also passively heated by lower-leg immersion into hot water of 42 degrees C under an ambient temperature of 25 degrees C and relative humidity of 50%. Esophageal temperature, mean skin temperature, sweating rate (SR), and heart rate were measured continuously during both trials. The number of ASG was determined every 4 min after the onset of sweating, whereas SGO was calculated by dividing SR by ASG. During both exercise and passive heating, SR increased abruptly during the first 8 min after onset of sweating, followed by a slower increase. Similarly for both protocols, the number of ASG increased rapidly during the first 8 min after the onset of sweating and then ceased to increase further (P > 0.05). Conversely, SGO increased linearly throughout both perturbations. Our results suggest that changes in forearm sweating rate rely on both ASG and SGO during the initial period of exercise and passive heating, whereas further increases in SR are dependent on increases in SGO. (+info)The role of androgen receptors in the clinical course of nevus sebaceus of Jadassohn. (4/65)
Nevus sebaceus of Jadassohn (NSJ) is a benign, congenital hamartoma that often presents at birth, appears to regress in childhood, and grows during puberty, suggesting possible hormonal control. We studied 18 cases of NSJ from children and adults for immunohistochemical evidence of androgen receptor expression. The lesions were evaluated for location and pattern of immunostaining, and these findings were compared between age groups, sexes, and to androgen receptor expression in normal skin. Androgen receptor positivity was seen in the sebaceous glands, in eccrine glands with and without apocrine change, and rarely in keratinocytes in the sebaceous nevi. There were no significant differences in staining location or pattern between the age groups or sexes. Normal skin showed similar staining in the sebaceous glands but did not show staining of the eccrine glands or keratinocytes. Androgen receptors are present in all epithelial components of NSJ, but there is no change in androgen receptor expression during puberty. (+info)Skin morphological changes in growth hormone deficiency and acromegaly. (5/65)
OBJECTIVE: To evaluate the histomorphology of skin and its appendages, especially eccrine sweat glands, in patients with GH disorders, because reduced sweating ability in patients with growth hormone deficiency (GHD) is associated with increased risk of hyperthermia under stressed conditions. DESIGN AND METHODS: A skin biopsy was obtained from 17 patients with GHD treated with GH, five patients with untreated GHD, 10 patients with active acromegaly and 13 healthy controls. RESULTS: The sweat secretion rate (SSR) was significantly decreased in both the untreated (median 41 mg/30 min, range 9-79 mg/30 min) and the GH-treated (median 98 mg/30 min, range 28-147 mg/30 min) patients with GHD compared with that in controls (median 119 mg/30 min, range 90-189 mg/30 min; P=0.001 and 0.01 respectively). Epidermal thickness was significantly decreased in both untreated (median 39 microm, range 28-55 microm) and GH-treated patients with GHD (median 53 microm, range 37-100 microm), compared with that in controls (median 66 microm, range 40-111 microm; P<0.02). A statistically non-significant tendency towards thinner epidermis (median 59 microm, range 33-83 microm) was recorded in acromegalic patients (P=0.08) compared with controls. There was no significant difference in the area of the sebaceous glands in the biopsies between the three groups and the controls. The area of eccrine sweat gland glomeruli was significantly decreased in the untreated patients with GHD (median 16407 microm2, range 12758-43976 microm2) compared with that in controls (median 29446 microm2, range 13511-128661 microm2; P=0.03), but there was no significant difference between the GH-treated patients with GHD and controls. CONCLUSIONS: We conclude that GH, either directly or via IGF-I, may have both a structural and a functional effect on human skin and its appendages, and that patients with GHD have histomorphological changes in skin compared with controls. Importantly, these changes are not fully reversed despite long-term and adequate GH treatment in patients with childhood onset GHD. (+info)Requirement of NF-kappaB/Rel for the development of hair follicles and other epidermal appendices. (6/65)
NF-kappaB/Rel transcription factors and IkappaB kinases (IKK) are essential for inflammation and immune responses, but also for bone-morphogenesis, skin proliferation and differentiation. Determining their other functions has previously been impossible, owing to embryonic lethality of NF-kappaB/Rel or IKK-deficient animals. Using a gene targeting approach we have ubiquitously expressed an NF-kappaB super-repressor to investigate NF-kappaB functions in the adult. Mice with suppressed NF-kappaB revealed defective early morphogenesis of hair follicles, exocrine glands and teeth, identical to Eda (tabby) and Edar (downless) mutant mice. These affected epithelial appendices normally display high NF-kappaB activity, suppression of which resulted in increased apoptosis, indicating that NF-kappaB acts as a survival factor downstream of the tumor necrosis factor receptor family member EDAR. Furthermore, NF-kappaB is required for peripheral lymph node formation and macrophage function. (+info)Evidence for sodium-coupled acid-base transport across the basolateral membrane of the reabsorptive duct of the human eccrine sweat gland. (7/65)
Intracellular pH was measured in isolated nonperfused ducts of human eccrine sweat glands in vitro to investigate basolateral acid-base transport mechanisms. Bath sodium removal led to a bicarbonate-independent, 4-acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic acid insensitive acidification. The recovery of this acidification was ethylisopropyl amiloride sensitive, suggestive of basolateral sodium:hydrogen exchange. Whereas bath chloride removal led to a small acidification this was not 4-acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic acid sensitive and its causes remain unclear. Elevation of bath potassium to depolarize the basolateral membrane led to a small alkalinization but this was not mimicked by addition of barium or chloride removal. As chloride removal and barium addition would be expected to cause larger depolarizations than potassium elevation these observations do not support a major role for electrogenic acid-base transport. In conclusion, although this study does not support a major role for electrogenic acid-base transport, it has demonstrated the basolateral presence of sodium-coupled acid-base transport in the reabsorptive duct of the human eccrine sweat gland, which most likely represents a sodium:hydrogen exchanger involved in regulation of intracellular pH. (+info)Histochemical and immunohistochemical markers for human eccrine and apocrine sweat glands: an aid for histopathologic differentiation of sweat gland tumors. (8/65)
Apocrine and eccrine sweat glands are distinct in function, although they are closely related to each other developmentally and morphologically. In certain sweat gland tumors, it is difficult to differentiate between eccrine or apocrine sweat glands. Therefore, this paper reviews histochemical and immunohistochemical markers to differentiate apocrine and eccrine sweat glands with the aim of better understanding the structural and functional characteristics of these sweat glands. Specific markers for apocrine sweat glands are as follows: neuraminidase sensitive anionic sites detected by cationic colloidal gold at pH 2.0, and mitochondrion-like secretory granules that have epidermal growth factor-like antigenicity. The following antibodies react with apocrine sweat glands but not with eccrine sweat glands; the antibodies raised against 70 kDa glycoprotein purified from human milk fat globule membranes, and HMFG-1 (1.10.F3) monoclonal antibody produced by immunizing mice with defatted human milk fat globule membranes. Markers for eccrine sweat glands are as follows: dark cell granules that have chondroitinase ABC sensitive anionic sites detected by cationic gold at pH 2.0 after pretreatment with EGTA, and intercellular canaliculi with high activity of alkaline phosphatase. CEA and GCDFP-15 are expressed in both eccrine and apocrine sweat glands. Anti-EMA monoclonal antibody (E29) stains both eccrine and apocrine sweat glands. (+info)Eccrine glands are the most numerous type of sweat glands in the human body, found in virtually all skin locations. They play a crucial role in thermoregulation by producing a watery sweat that cools the body when it evaporates on the skin surface. These glands are distributed over the entire body, with a higher concentration on the soles of the feet, palms of the hands, and forehead.
Structurally, eccrine glands consist of two main parts: the coiled secretory portion located in the dermis and the straight duct that extends through the dermis and epidermis to reach the skin surface. The secretory portion is lined with a simple cuboidal epithelium, while the duct is lined with a simple squamous or low cuboidal epithelium.
Eccrine glands are stimulated to produce sweat by the activation of the sympathetic nervous system, particularly through the release of acetylcholine at the neuro-glandular junction. The sweat produced is primarily water with small amounts of electrolytes, such as sodium, chloride, and potassium. This composition helps maintain the body's electrolyte balance while facilitating heat loss during physical exertion or in hot environments.
Sweat glands are specialized tubular structures in the skin that produce and secrete sweat, also known as perspiration. They are part of the body's thermoregulatory system, helping to maintain optimal body temperature by releasing water and heat through evaporation. There are two main types of sweat glands: eccrine and apocrine.
1. Eccrine sweat glands: These are distributed throughout the body, with a higher concentration on areas like the palms, soles, and forehead. They are responsible for producing a watery, odorless sweat that primarily helps to cool down the body through evaporation.
2. Apocrine sweat glands: These are mainly found in the axillary (armpit) region and around the anogenital area. They become active during puberty and produce a thick, milky fluid that does not have a strong odor on its own but can mix with bacteria on the skin's surface, leading to body odor.
Sweat glands are controlled by the autonomic nervous system, meaning they function involuntarily in response to various stimuli such as emotions, physical activity, or changes in environmental temperature.
Sebaceous glands are microscopic, exocrine glands that are found in the dermis of mammalian skin. They are attached to hair follicles and produce an oily substance called sebum, which is composed of triglycerides, wax esters, squalene, and metabolites of fat-producing cells (fatty acids, cholesterol). Sebum is released through a duct onto the surface of the skin, where it forms a protective barrier that helps to prevent water loss, keeps the skin and hair moisturized, and has antibacterial properties.
Sebaceous glands are distributed throughout the body, but they are most numerous on the face, scalp, and upper trunk. They can also be found in other areas of the body such as the eyelids (where they are known as meibomian glands), the external ear canal, and the genital area.
Abnormalities in sebaceous gland function can lead to various skin conditions, including acne, seborrheic dermatitis, and certain types of skin cancer.
Carcinoma of the skin appendages refers to a type of cancer that originates in the specialized cells of the skin's sweat glands, hair follicles, or sebaceous glands. These cancers are relatively rare and can present as various subtypes, including eccrine carcinoma, apocrine carcinoma, hidradenocarcinoma, and malignant adnexal tumors.
The symptoms of skin appendage carcinomas may include:
1. A firm, painless lump or nodule under the skin that may be skin-colored, red, or blue.
2. Ulceration, crusting, or bleeding from the lesion.
3. Itching, burning, or pain in the affected area.
4. Lymph node enlargement near the tumor site.
Treatment typically involves surgical excision of the tumor, often followed by radiation therapy and/or chemotherapy to ensure complete removal and reduce the risk of recurrence. Regular follow-up appointments with a dermatologist or oncologist are essential for monitoring and early detection of any potential recurrences or new primary cancers.
Sebum is an oily, waxy substance that is produced by the sebaceous glands in the skin of mammals. It is composed mainly of triglycerides, wax esters, squalene, and free fatty acids, as well as smaller amounts of metabolites and other substances. Sebum plays an important role in the maintenance of the skin's barrier function and in the regulation of its moisture levels. It also has antimicrobial properties that help to protect the skin from infection. Excessive sebum production can contribute to the development of acne and other skin conditions.
An encyclopedia is a comprehensive reference work containing articles on various topics, usually arranged in alphabetical order. In the context of medicine, a medical encyclopedia is a collection of articles that provide information about a wide range of medical topics, including diseases and conditions, treatments, tests, procedures, and anatomy and physiology. Medical encyclopedias may be published in print or electronic formats and are often used as a starting point for researching medical topics. They can provide reliable and accurate information on medical subjects, making them useful resources for healthcare professionals, students, and patients alike. Some well-known examples of medical encyclopedias include the Merck Manual and the Stedman's Medical Dictionary.
A hair follicle is a part of the human skin from which hair grows. It is a complex organ that consists of several layers, including an outer root sheath, inner root sheath, and matrix. The hair follicle is located in the dermis, the second layer of the skin, and is surrounded by sebaceous glands and erector pili muscles.
The hair growth cycle includes three phases: anagen (growth phase), catagen (transitional phase), and telogen (resting phase). During the anagen phase, cells in the matrix divide rapidly to produce new hair fibers that grow out of the follicle. The hair fiber is made up of a protein called keratin, which also makes up the outer layers of the skin and nails.
Hair follicles are important for various biological functions, including thermoregulation, sensory perception, and social communication. They also play a role in wound healing and can serve as a source of stem cells that can differentiate into other cell types.
Medically, hair is defined as a threadlike structure that grows from the follicles found in the skin of mammals. It is primarily made up of a protein called keratin and consists of three parts: the medulla (the innermost part or core), the cortex (middle layer containing keratin filaments) and the cuticle (outer layer of overlapping scales).
Hair growth occurs in cycles, with each cycle consisting of a growth phase (anagen), a transitional phase (catagen), and a resting phase (telogen). The length of hair is determined by the duration of the anagen phase.
While hair plays a crucial role in protecting the skin from external factors like UV radiation, temperature changes, and physical damage, it also serves as an essential aspect of human aesthetics and identity.
Osteitis deformans, also known as Paget's disease of bone, is a chronic disorder of the bone characterized by abnormal turnover and remodeling of the bone. In this condition, the bone becomes enlarged, thickened, and deformed due to excessive and disorganized bone formation and resorption.
The process begins when the bone-remodeling cycle is disrupted, leading to an imbalance between the activity of osteoclasts (cells that break down bone) and osteoblasts (cells that form new bone). In Paget's disease, osteoclasts become overactive and increase bone resorption, followed by an overzealous response from osteoblasts, which attempt to repair the damage but do so in a disorganized manner.
The affected bones can become weakened, prone to fractures, and may cause pain, deformities, or other complications such as arthritis, hearing loss, or neurological symptoms if the skull or spine is involved. The exact cause of Paget's disease remains unknown, but it is believed that genetic and environmental factors play a role in its development.
Early diagnosis and treatment can help manage the symptoms and prevent complications associated with osteitis deformans. Treatment options include medications to slow down bone turnover, pain management, and orthopedic interventions when necessary.
Paget's disease of the nipple, also known as Paget's disease of the breast, is a rare type of cancer that starts in the breast ducts and spreads to the skin of the nipple and areola. The symptoms often include redness, itching, tingling, or burning of the nipple, which can also become flaky, scaly, or crusty. There may also be a discharge from the nipple.
The exact cause of Paget's disease is not known, but it is thought to be associated with underlying breast cancer in about 90% of cases. It is more common in women over the age of 50 and is usually diagnosed through a biopsy of the affected skin. Treatment typically involves removing the affected breast tissue, which may include a mastectomy, followed by radiation therapy.
It's important to note that Paget's disease of the nipple is different from benign paget's disease of the breast, which is a non-cancerous condition that can cause similar symptoms but does not spread to other parts of the body.
Extramammary Paget disease (EMPD) is a rare skin condition that typically affects the genital or anal areas, but can also occur in other areas such as the axillae (armpits) or male nipples. It is named similar to Paget's disease of the breast, but they are different conditions. EMPD is not related to breast cancer.
EMPD is characterized by the presence of abnormal cells called Paget cells in the skin. These cells can invade the surrounding tissue and may spread to other parts of the body (metastasize). The exact cause of EMPD is unknown, but it's thought to be associated with an underlying malignancy such as an adenocarcinoma in the adjacent area.
Symptoms of EMPD can include redness, itching, burning, or pain in the affected area. There may also be scaling, crusting, or oozing of the skin. The lesions associated with EMPD are typically slow-growing and can be mistaken for eczema, psoriasis, or other benign skin conditions.
Diagnosis of EMPD is usually made through a biopsy of the affected skin. Treatment typically involves surgical excision of the lesion, with wide margins to ensure complete removal of the abnormal cells. In some cases, radiation therapy or chemotherapy may be recommended if there are signs of spread (metastasis) to other parts of the body. Regular follow-up is important to monitor for recurrence or metastasis.
Inclusion body myositis (IBM) is a rare inflammatory muscle disease characterized by progressive weakness and wasting (atrophy) of skeletal muscles. The term "inclusion body" refers to the presence of abnormal protein accumulations within muscle fibers, which are observed under a microscope during muscle biopsy. These inclusions are primarily composed of aggregated forms of amyloid-β and tau proteins, similar to those found in neurodegenerative disorders like Alzheimer's disease.
IBM typically affects individuals over 50 years old, and it is more common in men than women. The disease usually starts with weakness in the wrist and finger flexors, making it difficult to perform tasks such as gripping, buttoning shirts, or lifting objects. Over time, the weakness spreads to other muscle groups, including the thigh muscles (quadriceps), resulting in difficulty climbing stairs or rising from a seated position.
The exact cause of inclusion body myositis remains unclear; however, both immune-mediated and degenerative mechanisms are believed to contribute to its pathogenesis. Currently, there is no cure for IBM, and treatment options are primarily aimed at managing symptoms and improving quality of life. Immunosuppressive medications may be used to target the inflammatory component of the disease; however, their efficacy varies among patients. Physical therapy and exercise programs can help maintain muscle strength and function as much as possible.
Intraductal carcinoma, noninfiltrating is a medical term used to describe a type of breast cancer that is confined to the milk ducts of the breast. It is also sometimes referred to as ductal carcinoma in situ (DCIS). Noninfiltrating means that the cancer cells have not spread beyond the ducts into the surrounding breast tissue or elsewhere in the body.
In this type of cancer, abnormal cells line the milk ducts and fill the inside of the ducts. These abnormal cells may look like cancer cells under a microscope, but they have not grown through the walls of the ducts into the surrounding breast tissue. However, if left untreated, noninfiltrating intraductal carcinoma can progress to an invasive form of breast cancer where the cancer cells spread beyond the milk ducts and invade the surrounding breast tissue.
It is important to note that while noninfiltrating intraductal carcinoma is considered a precancerous condition, it still requires medical treatment to prevent the development of invasive breast cancer. Treatment options may include surgery, radiation therapy, or hormone therapy, depending on the size and location of the tumor and other individual factors.
Mohs surgery, also known as Mohs micrographic surgery, is a precise surgical technique used to treat common types of skin cancer. It's primarily used for basal cell carcinomas and squamous cell carcinomas that have recurred, are large, aggressive, or in critical areas where preservation of healthy tissue is important, such as the face.
The procedure involves removing the visible tumor along with a thin layer of surrounding tissue. This layer is then processed and examined under a microscope while the patient waits. If cancer cells are found in the margin of the removed tissue, another layer of tissue is taken from that specific area and examined. This process continues until no cancer cells are found in the margins, ensuring complete removal of the tumor while minimizing the removal of healthy tissue.
The main advantage of Mohs surgery is its ability to accurately assess the depth and extent of the cancer, leading to high cure rates and improved cosmetic outcomes. However, it's a specialized procedure that requires extensive training and should be performed by a fellowship-trained Mohs surgeon.
A nipple is a small projection or tubular structure located at the center of the areola, which is the darker circle of skin surrounding the nipple on the breast. The primary function of the nipple is to provide a pathway for milk flow from the mammary glands during lactation in females.
The nipple contains smooth muscle fibers that contract and cause the nipple to become erect when stimulated, such as during sexual arousal or cold temperatures. Nipples can come in various shapes, sizes, and colors, and some individuals may have inverted or flat nipples. It is essential to monitor any changes in the appearance or sensation of the nipples, as these could be indicative of underlying medical conditions, such as breast cancer.
Eccrine sweat gland - Wikipedia
What does ECCRINE GLAND stand for?
What does eccrine glands mean?
Precise measurement of volume of eccrine sweat gland in mental sweating by optical coherence tomography | SpringerLink
Precise measurement of instantaneous volume of eccrine sweat gland in mental sweating by optical coherence tomography | (2015) ...
Primary Culture of Epithelial Cells from the Secretory Coil and the Reabsorptive Duct of the Human Eccrine Sweat Gland |...
Thermal Burns: Overview, Pathophysiology, Quantifying Burn Severity
Water Requirements During Exercise in the Heat - Nutritional Needs in Hot Environments - NCBI Bookshelf
Introduction to Dermatology - Wikibooks, open books for an open world
Hyperhidrosis: MedlinePlus Medical Encyclopedia
Granulosis Rubra Nasi: Background, Pathophysiology, Etiology
Perspiration | Sweat Glands, Evaporation & Regulation | Britannica
Maraviroc: Package Insert - Drugs.com
Tech: Tiny battery that runs off of SWEAT could power smartwatches and other wearables | Daily Mail Online
Accessing analytes in biofluids for peripheral biochemical monitoring | Nature Biotechnology
What actually causes body odor? | Popular Science
Naked Body: Working up a sweat | Interviews | Naked Scientists
Soft, skin-mounted microfluidic systems for measuring secretory fluidic pressures generated at the surface of the skin by...
Apocrine (sweat gland) cancer - Cancer Survivors Network
Neural control of sweat secretion: a review
August Portfolio | Roofing Contractor
Hyperhidrosis: Tips for managing
Accessory Structures of the Skin | Boundless Anatomy and Physiology | | Course Hero
Galvanic Skin Response (GSR) | Measure Electrodermal Activity | ADInstruments
Histology-World! Histology Testbank-Special Senses 3a
Tumors of the Skin in Dogs - Dog Owners - Merck Veterinary Manual
David I. Yule, Ph.D. | UR Medicine
Mammary Paget Disease: Practice Essentials, Background, Pathophysiology and Etiology
Is sweating good for your skin? | HowStuffWorks
Healing function of sweat glands declines wit | EurekAlert!
Secretion14
- The secretions are very watery that contain some electrolytes Apocrine glands produce a fatty secretion, thus giving away an odorous smell. (wikipedia.org)
- [ 3 ] Eccrine glands produce sweat, and an alteration in the rate of sweat secretion manifests as hypohidrosis or hyperhidrosis. (medscape.com)
- Secretion of sweat by eccrine glands in the skin. (britannica.com)
- β-adrenoceptors are found in adipocytes as well as apocrine glands, and these receptors may mediate lipid secretion from apocrine glands for sweat secretion. (nih.gov)
- Ca 2+ and cyclic adenosine monophosphate play a part in the secretion of lipids and proteins from apocrine glands for sweat secretion. (nih.gov)
- The translocation of aquaporin 5 plays an important role in sweat secretion from eccrine glands. (nih.gov)
- The sebaceous gland is an example of a holocrine gland because its product of secretion (sebum) is released with remnants of dead cells. (coursehero.com)
- Regardless, the secretion of sebum out of the gland is helped along by the contraction of the arrector pili muscle. (coursehero.com)
- A Multicellular Model of Primary Saliva Secretion in the Parotid Gland. (rochester.edu)
- It is the excessive secretion of the eccrine sweat glands in response to stimuli like heat. (hpathy.com)
- But, the secretion of apocrine glands invites bacteria to feast upon it and causes strong body odor. (ayurvediccure.com)
- Yogurt is naturally acidic and it helps to control oil secretion of glands. (ayurvediccure.com)
- Sandalwood makes your skin dry and reduces sweat secretion of glands. (ayurvediccure.com)
- Although the histological features of apocrine and eccrine poromas are nearly identical, the presence of homogenous eosinophilic intraluminal secretion, lining cells with intensely eosinophilic cytoplasm, and small clusters of sebaceous cells surrounded by poroid cells is suggestive of apocrine lineage. (clinicaladvisor.com)
Secrete sweat3
- Simple sweat glands that secrete sweat directly onto the SKIN. (definitions.net)
- In humans, some of the more common skin appendages are hairs (sensation, heat loss, filter for breathing, protection), arrector pilli (smooth muscles that pull hairs straight), sebaceous glands (secrete sebum onto hair follicle, which oils the hair), sweat glands (can secrete sweat with strong odour (apocrine) or with a faint odour (merocrine or eccrine)), and nails (protection). (wikipedia.org)
- Eccrine glands are present all over, and typically secrete sweat that is mostly made of water. (popsci.com)
Types of sweat glands4
- The human body has two types of sweat glands: eccrine and apocrine. (popsci.com)
- There are two types of sweat glands. (roofingcontractor.com)
- The most numerous types of sweat glands in our skin, found almost everywhere on the body, are called eccrine glands. (coursehero.com)
- Introduction to Sweating Disorders There are two types of sweat glands: apocrine and eccrine. (merckmanuals.com)
Ducts8
- If acne is occurring, it is because these gland ducts are blocked. (wikipedia.org)
- Rana, R., Minhas, L.A. & Mubarik, A. Histological study of human sublingual gland with special emphasis on intercalated and striated ducts. (nature.com)
- Zenk, J., Hosemann, W. G. & Iro, H. Diameters of the main excretory ducts of the adult human submandibular and parotid gland: a histologic study. (nature.com)
- They are typically larger than eccrine glands and their ducts tend to open into hair follicles instead of hairless areas of skin. (coursehero.com)
- Sebaceous gland ducts thus usually open up into the upper part of a hair follicle, called the infundibulum. (coursehero.com)
- However, some sebaceous gland ducts open directly onto our skin surface such as at the corner of the mouth and the glans penis. (coursehero.com)
- Miliaria is a common skin disease caused by blockage and/or inflammation of eccrine sweat ducts. (dermnetnz.org)
- Miliaria is thought to be caused by blockage of the sweat ducts, which results in the leakage of eccrine sweat into the epidermis or dermis. (medscape.com)
Duct3
- The infundibulum is part of the pilosebaceous canal, the one responsible for discharging sebum and one that is composed of the infundibulum and the short duct of the sebaceous gland itself. (coursehero.com)
- Poroma is a benign adnexal neoplasm of the intraepidermal portion of the sweat gland duct, called the acrosyringium . (clinicaladvisor.com)
- A hyperkeratotic plug may appear to obstruct the eccrine duct, but this is now believed to be a late change and not the precipitating cause of the sweat blockage. (medscape.com)
Perspiration3
- perspiration , in most mammals, water given off by the intact skin, either as vapour by simple evaporation from the epidermis ( insensible perspiration) or as sweat , a form of cooling in which liquid actively secreted from sweat glands evaporates from the body surface. (britannica.com)
- Eccrine glands trigger perspiration to keep our core temperature regulated, while apocrine glands release sweat as a response to nerves or stimulation, such as exercise. (howstuffworks.com)
- The patch provides an unambiguous digital result that can be read in an electrochromic display and yields 95% sensitivity and 100% specificity when tested with artificial eccrine perspiration samples. (nature.com)
Autonomic Nervou1
- Human eccrine sweat glands, present on the palmar surfaces of the hands and bottoms of the feet, are innervated by the sympathetic branch of the autonomic nervous system (ANS). (adinstruments.com)
Secretions1
- They are coiled tubular glands that discharge their secretions directly onto the surface of the skin. (coursehero.com)
Million sweat glands2
- People typically have 2.6 million sweat glands distributed within their skin. (roofingcontractor.com)
- The body has 2-4 million sweat glands . (harcourthealth.com)
Contain proteins and fatty acids2
- Sweat from the apocrine glands contain proteins and fatty acids, making it thicker and yellowish in color (hence those underarm stains). (roofingcontractor.com)
- In addition to the aforementioned ingredients, sweat from apocrine glands may contain proteins and fatty acids. (howstuffworks.com)
Stimuli1
- There are many other stimuli that can activate exocrine glands. (thenakedscientists.com)
Mammary glands3
- Although the nipples do have the mammary glands, these are known as modified sweat glands. (wikipedia.org)
- These are located in the inguinal and axillary regions of the body, and include the mammary glands as well as the creaminess variants. (wikipedia.org)
- Hair follicles, sebaceous glands, sweat glands, apocrine glands, and mammary glands are considered epidermal glands or epidermal appendages, because they develop as downgrowths or diverticula of the epidermis into the dermis. (medscape.com)
Salivary Glands2
- in Histopathology of the Salivary Glands 1-22, https://doi.org/10.1007/978-3-540-46915-5_1 (Springer, Berlin and Heidelberg, Germany, 2014). (nature.com)
- AN - do not confuse with SURGICAL STOMATA HN - 2008 BX - Diaphragmatic Stomata BX - Lymphatic Stomata BX - Stomata, Peritoneal FX - Surgical Stomas MH - Von Ebner Glands UI - D054838 MN - A03.556.500.760.906 MN - A10.336.779.906 MN - A14.549.760.906 MS - Small tubulo-alveolar salivary glands located beneath the circumvallate and foliate papillae. (bvsalud.org)
Miliaria3
- More commonly known as prickly rash or heat rash, miliaria occurs when the eccrine glands become blocked, which results in a series of red bumps. (howstuffworks.com)
- Miliaria profunda (tropical anhidrosis ) is the result of sweat leaking from the sweat glands into the middle layer of skin (blockage at or below the dermoepidermal junction) following repeated episodes of miliaria rubra. (dermnetnz.org)
- Miliaria is a common disorder of the eccrine sweat glands that often occurs in conditions of increased heat and humidity. (medscape.com)
Portion of the sweat gland1
- It is in the coiled secretory portion of the sweat gland where the sweat is actually produced. (coursehero.com)
Appendages2
- Types of appendages include hair, glands, and nails. (wikipedia.org)
- Hair follicle and skin glands and appendages, Steroid synthesis and function in skin, hair follicles and sebaceous glands, Basal cell carcinoma Gli and Sonic Hedgehog. (qmul.ac.uk)
Active at puberty1
- Compared to apocrine glands, eccrine glands are smaller, are active from birth (apocrine glands become active at puberty) and produce a sweat that is free of proteins and fatty acids. (roofingcontractor.com)
Typically2
- Sebaceous glands are typically found in the opening shafts of hair. (wikipedia.org)
- The sebaceous glands are typically localised to regions containing hair follicles, as well as the face and scalp. (futurelearn.com)
Exocrine7
- How do our exocrine glands work? (thenakedscientists.com)
- How do we sweat, how do our exocrine glands work? (thenakedscientists.com)
- But, dotted around the body, in numerous places, these cells form little structures that can secrete an array of different chemicals: we call these exocrine glands. (thenakedscientists.com)
- The exocrine glands are exquisitely arranged with a mix of different cell types in specific structures. (thenakedscientists.com)
- Exocrine glands are very sensitive to the world around us. (thenakedscientists.com)
- Exocrine glands are critically important for life - they take the simple watery bit of the blood and produce from it fluids that can propel our sperm and keep it swimming, allow us to digest and swallow our food, stay cool, feed babies, and less usefully allow our glasses to gradually slide down our nose. (thenakedscientists.com)
- Humans have 4 million exocrine sweat glands, which can be classified into two types: eccrine and apocrine glands. (nih.gov)
Sebaceous gland2
- Cross sectional image of skin showing a sweat gland and a sebaceous gland. (coursehero.com)
- Biology of the hair follicle and sebaceous gland. (qmul.ac.uk)
SKIN24
- When the body temperature rises, the sympathetic nervous system stimulates the eccrine sweat glands to secrete water to the skin surface, where it cools the body by evaporation. (britannica.com)
- During periods of activity, sweat glands produce pressures associated with osmotic effects to drive liquid to the surface of the skin. (rsc.org)
- This paper introduces a thin, soft wearable microfluidic system that mounts onto the surface of the skin to enable precise and routine measurements of secretory fluidic pressures generated at the surface of the skin by eccrine sweat glands (surface SPSG, or s-SPSG) at nearly any location on the body. (rsc.org)
- Sweat glands are located deep within the skin and primarily regulate temperature. (coursehero.com)
- The major sweat glands of the human body, found in virtually all skin, produce a clear, odorless substance, consisting primarily of water and NaCl. (coursehero.com)
- These are also the glands largely responsible for body smells, as their excretions are converted by skin bacteria into various chemicals we associated with body odor. (coursehero.com)
- Sebaceous glands are found in most of the skin (except the palms of the hands and the soles of the feet). (coursehero.com)
- A thick oily substance, secreted by the sebaceous glands of the skin, that consists of fat and cellular debris. (coursehero.com)
- The sebaceous glands are located in the dermis, the middle layer of the skin, and they develop from the epithelial cells of the hair follicle itself (the external root sheath of the hair follicle). (coursehero.com)
- Galvanic Skin Response (GSR) measures changes in sweat gland activity on the skin as an indication of physiological or psychological arousal. (adinstruments.com)
- These glands respond readily to a person's mental and emotional state are are often more responsive than other variables such as skin temperature. (adinstruments.com)
- When the eccrine glands fill with fluid, the skin resistance decreases and the conductance increase. (adinstruments.com)
- A group of scientists and dermatologists are now looking at the role sweat glands play in how aging skin recovers from wounds. (eurekalert.org)
- It wasn't that the sweat glands were less active in older people, rather, that the environment in the aging skin had been slowly degraded, making the skin structures less able to support the new cells that were generated. (eurekalert.org)
- Chronic sun exposure is an important factor that damages skin structures that normally support sweat glands. (eurekalert.org)
- BDS: Lectures on Cell cycle, epithelium, skin and glands. (qmul.ac.uk)
- Skin and Glands microanatomy. (qmul.ac.uk)
- Beyond the Adrenal Gland: Dysfunctional Skin-Derived Glucocorticoid Synthesis Promotes Inflammation in Psoriasis: J Invest Dermatol. (qmul.ac.uk)
- These proteins are involved in signal transduction from ectoderm to mesenchyme during development of the fetus and are indispensable for the differentiation of ectoderm-derived structures such as eccrine sweat glands, teeth, hair, skin, and/or nails. (springer.com)
- Ectodermal dysplasias comprise a large group of congenital developmental disorders of at least two ectoderm-derived structures: eccrine sweat glands, teeth, hair, skin, and/or nails. (springer.com)
- Humans have three different types of skin glands. (livescience.com)
- Sebaceous glands, found all over the body but especially on the face and head, produce oils to protect the skin and hair. (livescience.com)
- A) Immunohistochemical stain of Rickettsia rickettsii antigens (red) in inflamed blood vessel adjacent to eccrine gland in a skin biopsy specimen from case-patient 1. (cdc.gov)
- This blockage results in the leakage of sweat en route to the skin surface, either in the dermis or epidermis, with relative anhidrosis. (medscape.com)
Humans4
- Sweat glands, although found in the majority of mammals, constitute the primary means of heat dissipation only in certain hoofed animals (orders Artiodactyla and Perissodactyla) and in primates, including humans. (britannica.com)
- However, although both humans and horses sweat liberally, their sweat glands are not the same, creating different concerns for dehydration and exercise recovery. (alltech.com)
- Humans largely have eccrine sweat glands, while horses predominantly have apocrine sweat glands. (alltech.com)
- Our abundance of eccrine glands and relative lack of apocrine glands makes humans, in a word, weird. (livescience.com)
Apocrine sweat9
- The apocrine sweat glands , associated with the presence of hair in human beings (as on the scalp, the armpit, and the genital region), continuously secrete a concentrated fatty sweat into the gland tube. (britannica.com)
- Apocrine sweat glands are mostly confined to the underarm area. (roofingcontractor.com)
- Apocrine sweat glands are coiled tubular glands that discharge in the canals of hair follicles. (coursehero.com)
- The glands of Moll in the eyelid are apocrine sweat glands. (histology-world.com)
- But equine apocrine sweat glands do not retain large quantities of electrolytes, so horses' sweat tends to be isotonic or hypertonic, containing the same to higher concentrations of electrolytes compared to other bodily fluids. (alltech.com)
- This type of sweat is particularly troublesome because it's produced by the apocrine sweat glands and contains fat and proteins. (harcourthealth.com)
- The groin is one of only two other places outside of the armpits where sweat is produced by the apocrine sweat glands. (harcourthealth.com)
- Scalp sweat is also produced by the apocrine sweat glands, which are in areas where there's an abundance of hair follicles. (harcourthealth.com)
- While bacterial metabolism of apocrine sweat usually causes the malodour, eccrine sweating can also become offensive after ingestion of certain foods, such as garlic and alcohol. (racgp.org.au)
Armpits4
- Apocrine glands, however, are located in targeted areas of the body-the armpits, for example-and they don't really do much to cool you down. (popsci.com)
- The apocrine glands are found in places like the armpits, scrotum, anus, and labia majora. (coursehero.com)
- But unlike the armpits, the sweat on feet comes from the eccrine sweat glands. (harcourthealth.com)
- The apocrine glands are primarily found in the axillary regions, ie the armpits. (futurelearn.com)
Soles3
- The main mechanism behind primary hyperhidrosis is the excessive stimulation of the sweat centres of the hypothalamus in response to emotion leading to increased secretory activity of the eccrine sweat glands of the palms and soles. (hpathy.com)
- Surprisingly, the most concentrated area of sweat glands on the body is the soles of feet. (harcourthealth.com)
- The eccrine glands are usually found throughout the body, but the highest densities are found in the palms and soles. (futurelearn.com)
Rubra2
- Granulosis rubra nasi is described as a benign, autosomal dominant familial disease of children involving the eccrine glands of the nose, cheeks, and chin. (medscape.com)
- Granulosis rubra nasi is a nonneoplastic disorder of the eccrine glands, possibly representing a unique form of sweat retention. (medscape.com)
Occurs1
- Body odor or pungent smell of the body occurs when sweat glands secrete too much. (ayurvediccure.com)
Genitals2
- Sweat glands are distributed all over the body except nipples and outer genitals. (wikipedia.org)
- These glands are present in underarms and genitals. (ayurvediccure.com)
Hyperhidrosis1
- People with hyperhidrosis appear to have overactive sweat glands. (medlineplus.gov)
Disorders1
- Nonneoplastic disorders of the eccrine glands. (medscape.com)
Fluid1
- These glands secrete an antibacterial moisture known as sebum fluid. (wikipedia.org)
Produce sweat1
- Eccrine glands, found all over the body, produce sweat to regulate temperature, but this sweat is mostly water with trace amounts of salt and other compounds. (livescience.com)
Benign1
- Syringomas are thought to be benign neoplasms of eccrine gland origin. (medscape.com)
Tumor1
- 1 First described in 1956, poroma was originally identified as a tumor originating from the eccrine sweat gland. (clinicaladvisor.com)
Human4
- Human eccrine sweat is essentially a dilute sodium chloride solution with trace amounts of other plasma electrolytes. (britannica.com)
- The human eccrine glands act as variable resistors. (adinstruments.com)
- Human eccrine sweat glands retain large quantities of electrolytes, producing what's called hypotonic sweat, which contains lower concentrations of electrolytes when compared to other bodily fluids. (alltech.com)
- Eccrine glands are the most abundant sweat glands on the human body , setting people apart from most other mammals. (livescience.com)
Hair1
- Areas of the face have an amazing amount of hair follicles and eccrine sweat glands, which means excessive sweating is possible. (harcourthealth.com)
Body11
- Sweat glands, also known as sudoriferous glands, are distributed over most of the body surface. (coursehero.com)
- The type of sweat gland that is least responsible for thermoregulation and most responsible for body odor. (coursehero.com)
- Sweat glands, also called sudoriferous glands, are simple tubular glands found almost everywhere on our body. (coursehero.com)
- These are the true sweat glands in the sense of helping to regulate body temperature. (coursehero.com)
- These glands, unlike the eccrine glands, serve virtually no role in the regulation of body temperature. (coursehero.com)
- Sebaceous glands are the oil secreting glands of your body. (coursehero.com)
- The researchers had already determined eccrine sweat glands, which are located throughout the body, are important for wound closure. (eurekalert.org)
- Eccrine glands secrete sweating that has no bad smell and it helps to keep your body cool. (ayurvediccure.com)
- Dogs, for example, pant to regulate their body temperature, because their eccrine glands are limited mostly to the bottoms of their paws. (livescience.com)
- Eccrine glands are sympathetically innervated, distributed over the entire body, and active from birth. (msdmanuals.com)
- Sudiferous (sweat) glands are divided into eccrine glands, found all over the body, and apocrine glands found in the axilla, breast and groin region. (racgp.org.au)
Possible meanings1
- This dictionary definitions page includes all the possible meanings, example usage and translations of the word eccrine glands . (definitions.net)
Temperature2
- Thus, eccrine sweat is an important mechanism for temperature control. (britannica.com)
- When sweat glands are working properly, they start producing sweat when the brain detects a sufficiently large rise in brain temperature. (thenakedscientists.com)
Unlike1
- Unlike eccrine glands, the exact function of apocrine glands is unknown and debated. (coursehero.com)
Found2
- Finally, there are the stinkiest glands of all: the apocrine glands, found in the armpit and genital areas. (livescience.com)
- modified apocrine glands are found in the external auditory. (merckmanuals.com)
Stimulation1
- Medicines -- Use of some medicines may prevent stimulation of sweat glands. (medlineplus.gov)