Two individuals derived from two FETUSES that were fertilized at or about the same time, developed in the UTERUS simultaneously, and born to the same mother. Twins are either monozygotic (TWINS, MONOZYGOTIC) or dizygotic (TWINS, DIZYGOTIC).
Disorders affecting TWINS, one or both, at any age.
Two off-spring from the same PREGNANCY. They are from a single fertilized OVUM that split into two EMBRYOS. Such twins are usually genetically identical and of the same sex.
Conjoined twins are a rare type of monozygotic twinning where genetically identical individuals form a single organism with varying degrees of physical connection and shared anatomy due to incomplete division during embryonic development.
Two offspring from the same PREGNANCY. They are from two OVA, fertilized at about the same time by two SPERMATOZOA. Such twins are genetically distinct and can be of different sexes.
Methods of detecting genetic etiology in human traits. The basic premise of twin studies is that monozygotic twins, being formed by the division of a single fertilized ovum, carry identical genes, while dizygotic twins, being formed by the fertilization of two ova by two different spermatozoa, are genetically no more similar than two siblings born after separate pregnancies. (Last, J.M., A Dictionary of Epidemiology, 2d ed)
The condition of carrying TWINS simultaneously.
The condition of carrying two or more FETUSES simultaneously.
Passage of blood from one fetus to another via an arteriovenous communication or other shunt, in a monozygotic twin pregnancy. It results in anemia in one twin and polycythemia in the other. (Lee et al., Wintrobe's Clinical Hematology, 9th ed, p737-8)
The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
Three individuals derived from three FETUSES that were fertilized at or about the same time, developed in the UTERUS simultaneously, and born to the same mother.
Selective abortion of one or more embryos or fetuses in a multiple gestation pregnancy. The usual goal is to improve the outcome for the remaining embryos or fetuses.
The external elements and conditions which surround, influence, and affect the life and development of an organism or population.
The age of the conceptus, beginning from the time of FERTILIZATION. In clinical obstetrics, the gestational age is often estimated as the time from the last day of the last MENSTRUATION which is about 2 weeks before OVULATION and fertilization.
Death of the developing young in utero. BIRTH of a dead FETUS is STILLBIRTH.
The outermost extra-embryonic membrane surrounding the developing embryo. In REPTILES and BIRDS, it adheres to the shell and allows exchange of gases between the egg and its environment. In MAMMALS, the chorion evolves into the fetal contribution of the PLACENTA.
Results of conception and ensuing pregnancy, including LIVE BIRTH; STILLBIRTH; SPONTANEOUS ABORTION; INDUCED ABORTION. The outcome may follow natural or artificial insemination or any of the various ASSISTED REPRODUCTIVE TECHNIQUES, such as EMBRYO TRANSFER or FERTILIZATION IN VITRO.
An infant during the first month after birth.
The experimental study of the relationship between the genotype of an organism and its behavior. The scope includes the effects of genes on simple sensory processes to complex organization of the nervous system.
The visualization of tissues during pregnancy through recording of the echoes of ultrasonic waves directed into the body. The procedure may be applied with reference to the mother or the fetus and with reference to organs or the detection of maternal or fetal disease.
The mass or quantity of heaviness of an individual at BIRTH. It is expressed by units of pounds or kilograms.
The combined effects of genotypes and environmental factors together on phenotypic characteristics.
The division of a ZYGOTE into two parts, each of which is capable of further development.
The aggregate of social and cultural institutions, forms, patterns, and processes that influence the life of an individual or community.
The systems and processes involved in the establishment, support, management, and operation of registers, e.g., disease registers.
Endoscopic examination, therapy or surgery of the fetus and amniotic cavity through abdominal or uterine entry.
Four individuals derived from four FETUSES that were fertilized at or about the same time, developed in the UTERUS simultaneously, and born to the same mother.
A condition of abnormally high AMNIOTIC FLUID volume, such as greater than 2,000 ml in the LAST TRIMESTER and usually diagnosed by ultrasonographic criteria (AMNIOTIC FLUID INDEX). It is associated with maternal DIABETES MELLITUS; MULTIPLE PREGNANCY; CHROMOSOMAL DISORDERS; and congenital abnormalities.
I'm sorry for any confusion, but "Denmark" is not a medical term and does not have a medical definition. It is a country located in northern Europe. If you have any questions related to medicine or health, I would be happy to try to help answer them.
The study of the patterns of ridges of the skin of the fingers, palms, toes, and soles.
A latent susceptibility to disease at the genetic level, which may be activated under certain conditions.
Clinical and laboratory techniques used to enhance fertility in humans and animals.
The outward appearance of the individual. It is the product of interactions between genes, and between the GENOTYPE and the environment.
A 'Twin Study' is an epidemiological research design that compares monozygotic (identical) and dizygotic (fraternal) twins to estimate the heritability of traits, diseases, or behaviors by examining the concordance rates between them.
I'm sorry for any confusion, but "Sweden" is not a medical term and does not have a medical definition. It is a country located in Northern Europe. If you have any questions related to medical topics or definitions, I would be happy to try to help answer them!
The sequence in which children are born into the family.

Genetic influences on cervical and lumbar disc degeneration: a magnetic resonance imaging study in twins. (1/1294)

OBJECTIVE: Degenerative intervertebral disc disease is common; however, the importance of genetic factors is unknown. This study sought to determine the extent of genetic influences on disc degeneration by classic twin study methods using magnetic resonance imaging (MRI). METHODS: We compared MRI features of degenerative disc disease in the cervical and lumbar spine of 172 monozygotic and 154 dizygotic twins (mean age 51.7 and 54.4, respectively) who were unselected for back pain or disc disease. An overall score for disc degeneration was calculated as the sum of the grades for disc height, bulge, osteophytosis, and signal intensity at each level. A "severe disease" score (excluding minor grades) and an "extent of disease" score (number of levels affected) were also calculated. RESULTS: For the overall score, heritability was 74% (95% confidence interval [95% CI] 64-81%) at the lumbar spine and 73% (95% CI 64-80%) at the cervical spine. For "severe disease," heritability was 64% and 79% at the lumbar and cervical spine, respectively, and for "extent of disease," heritability was 63% and 63%, respectively. These results were adjusted for age, weight, height, smoking, occupational manual work, and exercise. Examination of individual features revealed that disc height and bulge were highly heritable at both sites, and osteophytes were heritable in the lumbar spine. CONCLUSION: These results suggest an important genetic influence on variation in intervertebral disc degeneration. However, variation in disc signal is largely influenced by environmental factors shared by twins. The use of MRI scans to determine the phenotype in family and population studies should allow a better understanding of disease mechanisms and the identification of the genes involved.  (+info)

Discordance for Cornelia de Lange syndrome in twins. (2/1294)

A male infant, the first-born of twins, with features of Cornealia de Lange syndrome is described. His normal twin was discordnat for 3 of the 14 blood loci tested. Chromosomes from the affected infant appeared normal. Though the aetiological basis for the Cornealia de Lange syndrome remains obscure, most authorities accept genetic rather than environmental causation. The present findings of discordance for Cornelia de Lange syndrome in twins support this view but do not clarify the mode of inheritance.  (+info)

Diagnosis of twin reversed arterial perfusion sequence in the first trimester by transvaginal color Doppler ultrasound. (3/1294)

A case of twin reversed arterial perfusion (TRAP) sequence was diagnosed at 12 weeks' gestation using transvaginal color Doppler ultrasound, which demonstrated the presence of retrograde perfusion in the umbilical artery of the abnormal twin. Ultrasound imaging showed a monochorionic-diamniotic twin pregnancy with an inappropriately grown second twin, the morphological evaluation of which revealed an abnormal cephalic pole with acrania, diffuse subcutaneous edema and the presence of cardiac activity in an abnormal heart with a single chamber.  (+info)

Evidence for involvement of the type 1 angiotensin II receptor locus in essential hypertension. (4/1294)

Components of the renin-angiotensin system play an important role in the normal regulation of blood pressure. We carried out a comprehensive genetic linkage study of the genes involved in the renin-angiotensin cascade in Finnish hypertensive twins and their affected siblings. We found no evidence for linkage between essential hypertension and the genes coding for renin, angiotensinogen, angiotensin-converting enzyme, or kallikrein 1 in the 329 hypertensive individuals of 142 families studied. In contrast, two intragenic markers for the type 1 angiotensin II receptor (AT1) showed some evidence for linkage in the total sample. A closer examination of this gene locus was carried out using subgroups of nonobese sibpairs with early onset of hypertension and uniform geographical origin. These stratifications yielded suggestive evidence for linkage of hypertension to the genetic area containing the AT1 gene, with a maximal multipoint logarithm of the odds (LOD) score of 2.9. A genetic association study carried out in an independent series of 50 hypertensive cases and 122 normotensive controls showed an increase in the frequency of the A1166-->C allele of the AT1 gene in the hypertensive individuals. In a novel variant of model-free multipoint linkage analysis allowing linkage disequilibrium in the calculations, an LOD score of 5.13 was obtained. Sequence analyses of the entire coding region and 848 bp of promoter region in the DNA sample on 8 index samples did not reveal previously unpublished sequence variations. The data provide evidence that a common genetic variant of the AT1 gene locus influences the risk of essential hypertension in the Finnish population.  (+info)

Breast cancer risk in monozygotic and dizygotic female twins: a 20-year population-based cohort study in Finland from 1976 to 1995. (5/1294)

This population-based study investigated the occurrence of breast cancer over a 20-year period in a cohort of monozygotic (MZ) and dizygotic (DZ) twins in Finland. Altogether, 13,176 female twins of known zygosity who were living in Finland at the end of 1975 were identified from the Finnish Twin Cohort Study and followed-up for cancer through the Finnish Cancer Registry for the years 1976-1995. Standardized incidence ratios (SIRs) were calculated, based on national cancer incidence rates. The relative risk of breast cancer for MZ twins compared to DZ twins was decreased [SIR(MZ)/SIR(DZ) ratio = 0.78; 95% confidence interval (CI), 0.58-1.0]; the decreased risk for MZ twins (SIR = 0.76; 95% CI, 0.58-1.0) accounted for this result, whereas the risk for DZ twins did not differ from the general population risk (SIR = 0.98; 95% CI, 0.84-1.1). There was no risk decrease among MZ twins in other cancers related to reproductive behavior; i.e., number of children and age at first birth seem not to explain the decreased risk of breast cancer. Our results, which are in line with earlier studies on the same topic, suggest that prenatal influences or postnatal behavioral factors may protect MZ female twins from breast cancer.  (+info)

Diagnostic utility of metabolic exercise testing in a patient with cardiovascular disease. (6/1294)

Disproportionate exercise limitation in patients with cardiovascular disease is a common problem faced by clinical cardiologists and other physicians. Symptoms may be attributed to psychological factors or hypothetical pathophysiological mechanisms that are difficult to confirm clinically. This case report describes how the use of metabolic exercise testing in a 28 year old woman with morphologically and haemodynamically mild hypertrophic cardiomyopathy and severe exercise limitation led to the diagnosis of an alternative cause for the patient's symptoms, namely a primary disturbance of the mitochondrial respiratory chain probably caused by a nuclear encoded gene defect.  (+info)

Broad ligament twin pregnancy following in-vitro fertilization. (7/1294)

We report the first case of an ectopic twin pregnancy in the broad ligament following in-vitro fertilization and embryo transfer in a patient with a previous ipsilateral (left) salpingo-oophorectomy. The previous surgery was for endometriosis. We discuss the possible contribution of the embryo transfer technique, limitations of preventive measures and importance of transvaginal ultrasound in establishing the diagnosis.  (+info)

The de Lange syndrome in one of twins. (8/1294)

A pair of female monozygotic twins, one of them affected by the de Lange syndrome is described for the first time. Monozygosity was established by most of the accepted standards in use at the present time. Speculation is offered as to whether the discordance in the manifestation of the syndrome provides any clues for understanding its controversial pathogenesis. In this regard two genetic mechanisms are discussed. One is the hypothesis of a chromosomal or mitotic instability. The other possibility would be a postzygotic new mutation of a gene or large effect.  (+info)

In the field of medicine, twins are defined as two offspring produced by the same pregnancy. They can be either monozygotic (identical) or dizygotic (fraternal). Monozygotic twins develop from a single fertilized egg that splits into two separate embryos, resulting in individuals who share identical genetic material. Dizygotic twins, on the other hand, result from the fertilization of two separate eggs by two different sperm cells, leading to siblings who share about 50% of their genetic material, similar to non-twin siblings.

'Diseases in Twins' is a field of study that focuses on the similarities and differences in the occurrence, development, and outcomes of diseases among twins. This research can provide valuable insights into the genetic and environmental factors that contribute to various medical conditions.

Twins can be classified into two types: monozygotic (identical) and dizygotic (fraternal). Monozygotic twins share 100% of their genes, while dizygotic twins share about 50%, similar to non-twin siblings. By comparing the concordance rates (the likelihood of both twins having the same disease) between monozygotic and dizygotic twins, researchers can estimate the heritability of a particular disease.

Studying diseases in twins also helps understand the role of environmental factors. When both twins develop the same disease, but they are discordant for certain risk factors (e.g., one twin smokes and the other does not), it suggests that the disease may have a stronger genetic component. On the other hand, when both twins share similar risk factors and develop the disease, it implies that environmental factors play a significant role.

Diseases in Twins research has contributed to our understanding of various medical conditions, including infectious diseases, cancer, mental health disorders, and developmental disorders. This knowledge can lead to better prevention strategies, early detection methods, and more targeted treatments for these diseases.

Monozygotic twins, also known as identical twins, are derived from a single fertilized egg (ovum) that splits and develops into two separate embryos. This results in the formation of genetically identical individuals who share the same genetic material, with the exception of potential mutations that may occur after the split. Monozygotic twins have the same sex, blood type, and other genetic traits. They are a unique pair of siblings, sharing an extraordinary degree of resemblance in physical characteristics, abilities, and behaviors.

Conjoined twins, also known as Siamese twins, are a rare type of monozygotic (identical) twins who are born physically connected to each other. They develop from a single fertilized egg that fails to fully separate, resulting in various degrees of fusion between their bodies. The point of connection and the extent of sharing body parts can vary greatly between sets of conjoined twins. Some may be connected at the chest, abdomen, or hips, while others may share vital organs such as the heart or brain. Treatment options depend on the type of conjunction and whether separation is possible without causing harm to either twin. Conjoined twins occur in about 1 in every 200,000 live births.

Dizygotic twins, also known as fraternal twins, are a result of two separate sperm fertilizing two separate eggs during conception. These twins share about 50% of their genes, similar to any non-twin siblings. They may be of the same sex or different sexes and can vary in appearance, personality, and interests. Dizygotic twins typically do not share a placenta or a sac in the womb, but they may share a chorion (outer fetal membrane).

"Twin studies" is a type of research design used in medical and scientific research, particularly in the field of genetics. This method involves comparing similarities and differences between monozygotic (identical) twins and dizygotic (fraternal) twins to estimate the heritability of certain traits or conditions.

Monozygotic twins share 100% of their genetic material, while dizygotic twins share only about 50%, similar to non-twin siblings. By comparing the concordance rates (the likelihood that both twins in a pair will have the same trait or condition) between monozygotic and dizygotic twins, researchers can estimate the proportion of variation in a trait that is due to genetic factors (heritability).

Twin studies can provide valuable insights into the genetic and environmental contributions to various traits and conditions, including physical characteristics, cognitive abilities, personality traits, and susceptibility to diseases. However, it's important to note that twin studies have limitations, such as the potential for environmental influences to be confounded with genetic factors, and the assumption that monozygotic twins share all of their genetic material, which is not always the case due to rare genetic events like mutations during development.

Twin pregnancy refers to a type of multiple pregnancy where a woman is carrying two fetuses simultaneously. There are two types of twin pregnancies: monozygotic (identical) and dizygotic (fraternal). Monoygotic twins occur when a single fertilized egg (zygote) splits and develops into two separate embryos, resulting in identical twins who share the same genetic material. Dizygotic twins, on the other hand, result from the fertilization of two separate eggs by two different sperm cells, leading to non-identical twins who have their own unique genetic material.

Twin pregnancies are associated with higher risks of complications compared to singleton pregnancies, including preterm labor, low birth weight, gestational diabetes, and preeclampsia. Close monitoring by healthcare providers is essential to ensure the best possible outcomes for both the mother and the twins.

Multiple pregnancy is a type of gestation where more than one fetus is carried simultaneously in the uterus. The most common forms of multiple pregnancies are twins (two fetuses), triplets (three fetuses), and quadruplets (four fetuses). Multiple pregnancies can occur when a single fertilized egg splits into two or more embryos (monozygotic) or when more than one egg is released and gets fertilized during ovulation (dizygotic). The risk of multiple pregnancies increases with the use of assisted reproductive technologies, such as in vitro fertilization. Multiple pregnancies are associated with higher risks for both the mother and the fetuses, including preterm labor, low birth weight, and other complications.

Fetofetal transfusion is a medical condition that can occur in pregnancies with multiple fetuses, such as twins or higher-order multiples. It refers to the transfer of blood from one fetus (donor) to another (recipient) through anastomotic connections in their shared placenta.

In some cases, these anastomoses can result in an imbalance in blood flow between the fetuses, leading to a net transfer of blood from one fetus to the other. This situation is more likely to occur when there is a significant weight or size difference between the fetuses, known as twin-to-twin transfusion syndrome (TTTS).

In TTTS, the recipient fetus receives an excess of blood, which can lead to high-output cardiac failure, hydrops, and potential intrauterine demise. Meanwhile, the donor fetus may become anemic, growth-restricted, and at risk for hypovolemia and intrauterine demise as well. Fetofetal transfusion can be diagnosed through ultrasound evaluation and managed with various interventions, including laser ablation of anastomotic vessels or fetoscopic surgery, depending on the severity and gestational age at diagnosis.

Pregnancy is a physiological state or condition where a fertilized egg (zygote) successfully implants and grows in the uterus of a woman, leading to the development of an embryo and finally a fetus. This process typically spans approximately 40 weeks, divided into three trimesters, and culminates in childbirth. Throughout this period, numerous hormonal and physical changes occur to support the growing offspring, including uterine enlargement, breast development, and various maternal adaptations to ensure the fetus's optimal growth and well-being.

In medical terms, triplets are a type of multiple pregnancy, where three offsprings (fetuses) develop simultaneously in the uterus of a single pregnant woman. This occurs when a woman releases more than one egg during ovulation, and all three eggs get fertilized by separate sperm cells. Triplets can also occur through the use of assisted reproductive technologies such as in vitro fertilization (IVF) where multiple embryos are transferred into the uterus.

Triplet pregnancies carry a higher risk of complications for both the mother and the offsprings compared to singleton or twin pregnancies, including preterm labor, low birth weight, and developmental issues. As such, they often require close monitoring and specialized care throughout the pregnancy.

Pregnancy reduction, multifetal refers to the medical procedure used to decrease the number of fetuses in a multiple pregnancy, such as twins or higher-order multiples (triplets, quadruplets, etc.). This is also known as selective reduction or selective termination. The goal of this procedure is to reduce the risk of complications associated with multifetal pregnancies, including preterm labor, low birth weight, and pregnancy loss.

The procedure typically involves an ultrasound-guided injection of a medication that stops the development of one or more fetuses. This is usually performed during the first trimester of pregnancy. The decision to undergo pregnancy reduction is often based on a variety of factors, including maternal age, medical history, and personal preferences. It's important to note that this procedure carries its own risks, such as infection, bleeding, and loss of the remaining fetuses, so it should be carefully considered and discussed with healthcare providers.

The term "environment" in a medical context generally refers to the external conditions and surroundings that can have an impact on living organisms, including humans. This includes both physical factors such as air quality, water supply, soil composition, temperature, and radiation, as well as biological factors such as the presence of microorganisms, plants, and animals.

In public health and epidemiology, the term "environmental exposure" is often used to describe the contact between an individual and a potentially harmful environmental agent, such as air pollution or contaminated water. These exposures can have significant impacts on human health, contributing to a range of diseases and disorders, including respiratory illnesses, cancer, neurological disorders, and reproductive problems.

Efforts to protect and improve the environment are therefore critical for promoting human health and preventing disease. This includes measures to reduce pollution, conserve natural resources, promote sustainable development, and mitigate the impacts of climate change.

Gestational age is the length of time that has passed since the first day of the last menstrual period (LMP) in pregnant women. It is the standard unit used to estimate the age of a pregnancy and is typically expressed in weeks. This measure is used because the exact date of conception is often not known, but the start of the last menstrual period is usually easier to recall.

It's important to note that since ovulation typically occurs around two weeks after the start of the LMP, gestational age is approximately two weeks longer than fetal age, which is the actual time elapsed since conception. Medical professionals use both gestational and fetal age to track the development and growth of the fetus during pregnancy.

Fetal death, also known as stillbirth or intrauterine fetal demise, is defined as the death of a fetus at 20 weeks of gestation or later. The criteria for defining fetal death may vary slightly by country and jurisdiction, but in general, it refers to the loss of a pregnancy after the point at which the fetus is considered viable outside the womb.

Fetal death can occur for a variety of reasons, including chromosomal abnormalities, placental problems, maternal health conditions, infections, and umbilical cord accidents. In some cases, the cause of fetal death may remain unknown.

The diagnosis of fetal death is typically made through ultrasound or other imaging tests, which can confirm the absence of a heartbeat or movement in the fetus. Once fetal death has been diagnosed, medical professionals will work with the parents to determine the best course of action for managing the pregnancy and delivering the fetus. This may involve waiting for labor to begin naturally, inducing labor, or performing a cesarean delivery.

Experiencing a fetal death can be a very difficult and emotional experience for parents, and it is important for them to receive supportive care from their healthcare providers, family members, and friends. Grief counseling and support groups may also be helpful in coping with the loss.

The chorion is the outermost fetal membrane that surrounds the developing conceptus (the embryo or fetus and its supporting structures). It forms early in pregnancy as an extraembryonic structure, meaning it arises from cells that will not become part of the actual body of the developing organism. The chorion plays a crucial role in pregnancy by contributing to the formation of the placenta, which provides nutrients and oxygen to the growing embryo/fetus and removes waste products.

One of the most important functions of the chorion is to produce human chorionic gonadotropin (hCG), a hormone that signals the presence of pregnancy and maintains the corpus luteum, a temporary endocrine structure in the ovary that produces progesterone during early pregnancy. Progesterone is essential for preparing the uterus for implantation and maintaining the pregnancy.

The chorion consists of two layers: an inner cytotrophoblast layer and an outer syncytiotrophoblast layer. The cytotrophoblast layer is made up of individual cells, while the syncytiotrophoblast layer is a multinucleated mass of fused cytotrophoblast cells. These layers interact with the maternal endometrium (the lining of the uterus) to form the placenta and facilitate exchange between the mother and the developing fetus.

In summary, the chorion is a vital extraembryonic structure in pregnancy that contributes to the formation of the placenta, produces hCG, and interacts with the maternal endometrium to support fetal development.

Pregnancy outcome refers to the final result or status of a pregnancy, including both the health of the mother and the newborn baby. It can be categorized into various types such as:

1. Live birth: The delivery of one or more babies who show signs of life after separation from their mother.
2. Stillbirth: The delivery of a baby who has died in the womb after 20 weeks of pregnancy.
3. Miscarriage: The spontaneous loss of a pregnancy before the 20th week.
4. Abortion: The intentional termination of a pregnancy before the fetus can survive outside the uterus.
5. Ectopic pregnancy: A pregnancy that develops outside the uterus, usually in the fallopian tube, which is not viable and requires medical attention.
6. Preterm birth: The delivery of a baby before 37 weeks of gestation, which can lead to various health issues for the newborn.
7. Full-term birth: The delivery of a baby between 37 and 42 weeks of gestation.
8. Post-term pregnancy: The delivery of a baby after 42 weeks of gestation, which may increase the risk of complications for both mother and baby.

The pregnancy outcome is influenced by various factors such as maternal age, health status, lifestyle habits, genetic factors, and access to quality prenatal care.

A newborn infant is a baby who is within the first 28 days of life. This period is also referred to as the neonatal period. Newborns require specialized care and attention due to their immature bodily systems and increased vulnerability to various health issues. They are closely monitored for signs of well-being, growth, and development during this critical time.

Behavioral genetics is a subfield of genetics that focuses on the study of the genetic basis of behavior. It seeks to understand how genes and environment interact to influence individual differences in behaviors such as personality traits, cognitive abilities, psychiatric disorders, and addiction. This field integrates knowledge from genetics, psychology, neuroscience, and statistics to investigate the complex relationship between genetic factors and behavioral outcomes. Research in behavioral genetics includes studies of twins, families, and adopted individuals, as well as animal models, to identify specific genes or genetic variations that contribute to the heritability of various behaviors. Understanding these genetic influences can provide insights into the prevention, diagnosis, and treatment of behavioral disorders.

Prenatal ultrasonography, also known as obstetric ultrasound, is a medical diagnostic procedure that uses high-frequency sound waves to create images of the developing fetus, placenta, and amniotic fluid inside the uterus. It is a non-invasive and painless test that is widely used during pregnancy to monitor the growth and development of the fetus, detect any potential abnormalities or complications, and determine the due date.

During the procedure, a transducer (a small handheld device) is placed on the mother's abdomen and moved around to capture images from different angles. The sound waves travel through the mother's body and bounce back off the fetus, producing echoes that are then converted into electrical signals and displayed as images on a screen.

Prenatal ultrasonography can be performed at various stages of pregnancy, including early pregnancy to confirm the pregnancy and detect the number of fetuses, mid-pregnancy to assess the growth and development of the fetus, and late pregnancy to evaluate the position of the fetus and determine if it is head down or breech. It can also be used to guide invasive procedures such as amniocentesis or chorionic villus sampling.

Overall, prenatal ultrasonography is a valuable tool in modern obstetrics that helps ensure the health and well-being of both the mother and the developing fetus.

Birth weight refers to the first weight of a newborn infant, usually taken immediately after birth. It is a critical vital sign that indicates the baby's health status and is used as a predictor for various short-term and long-term health outcomes.

Typically, a full-term newborn's weight ranges from 5.5 to 8.8 pounds (2.5 to 4 kg), although normal birth weights can vary significantly based on factors such as gestational age, genetics, maternal health, and nutrition. Low birth weight is defined as less than 5.5 pounds (2.5 kg), while high birth weight is greater than 8.8 pounds (4 kg).

Low birth weight babies are at a higher risk for various medical complications, including respiratory distress syndrome, jaundice, infections, and developmental delays. High birth weight babies may face challenges with delivery, increased risk of obesity, and potential metabolic issues later in life. Regular prenatal care is essential to monitor fetal growth and ensure a healthy pregnancy and optimal birth weight for the baby.

Gene-Environment Interaction (GEI) is a concept in genetics that refers to the way in which genetic variations and environmental factors interact to influence traits or disease susceptibility. It describes a situation where the effect of an environmental exposure on a particular trait or disease outcome is dependent on the genetic makeup of the individual, and vice versa.

In other words, GEI suggests that the impact of environmental factors on health outcomes may be different depending on a person's genetic background, and similarly, the influence of certain genes on health outcomes may depend on the presence or absence of specific environmental exposures. This interaction can help explain why some individuals are more susceptible to certain diseases or traits than others, even when exposed to similar environments.

GEI is an important concept in precision medicine, as understanding these interactions can help identify individuals who are at higher risk for certain diseases and develop targeted prevention and treatment strategies based on their genetic and environmental profiles.

Monozygotic twinning, also known as identical twinning, is a type of twin pregnancy that occurs when a single fertilized egg (ovum) splits into two embryos during the early stages of development. This results in the formation of two genetically identical individuals who share the same set of DNA and are therefore considered to be genetic clones of each other.

Monozygotic twinning is thought to occur in about 1 in every 250 pregnancies, making it less common than dizygotic (fraternal) twinning, which occurs when two separate eggs are fertilized by two different sperm. In monozygotic twinning, the timing of the split determines the type of placenta and amniotic sac each twin will have.

If the split occurs within the first few days after fertilization, the twins will typically develop in separate amniotic sacs and have their own individual placentas. If the split occurs later, the twins may share an amniotic sac (monoamniotic) or a placenta (monochorionic), or both (monochorionic-monoamniotic).

Monozygotic twinning is associated with some increased risks for pregnancy complications, such as preterm labor and delivery, low birth weight, and twin-to-twin transfusion syndrome, a rare condition in which blood flows unevenly between the twins through shared placental blood vessels. However, most monozygotic twins are born healthy and develop normally.

A "social environment" is not a term that has a specific medical definition, but it is often used in the context of public health and social sciences to refer to the physical and social conditions, relationships, and organized institutions that influence the health and well-being of individuals and communities.

The social environment includes factors such as:

* Social support networks (family, friends, community)
* Cultural norms and values
* Socioeconomic status (income, education, occupation)
* Housing and neighborhood conditions
* Access to resources (food, healthcare, transportation)
* Exposure to discrimination, violence, and other stressors

These factors can have a significant impact on health outcomes, as they can influence behaviors related to health (such as diet, exercise, and substance use), as well as exposure to disease and access to healthcare. Understanding the social environment is essential for developing effective public health interventions and policies that promote health equity and reduce health disparities.

A registry in the context of medicine is a collection or database of standardized information about individuals who share a certain condition or attribute, such as a disease, treatment, exposure, or demographic group. These registries are used for various purposes, including:

* Monitoring and tracking the natural history of diseases and conditions
* Evaluating the safety and effectiveness of medical treatments and interventions
* Conducting research and generating hypotheses for further study
* Providing information to patients, clinicians, and researchers
* Informing public health policy and decision-making

Registries can be established for a wide range of purposes, including disease-specific registries (such as cancer or diabetes registries), procedure-specific registries (such as joint replacement or cardiac surgery registries), and population-based registries (such as birth defects or cancer registries). Data collected in registries may include demographic information, clinical data, laboratory results, treatment details, and outcomes.

Registries can be maintained by a variety of organizations, including hospitals, clinics, academic medical centers, professional societies, government agencies, and industry. Participation in registries is often voluntary, although some registries may require informed consent from participants. Data collected in registries are typically de-identified to protect the privacy of individuals.

Fetoscopy is a minimally invasive surgical procedure that allows direct visualization of the fetus and the intrauterine environment through the use of a fiber-optic scope. It is typically performed during the second trimester of pregnancy to diagnose or treat various fetal conditions, such as twin-to-twin transfusion syndrome, congenital diaphragmatic hernia, or spina bifida. The procedure involves inserting a thin tube called a fetoscope through the mother's abdomen and uterus to access the fetus. Fetoscopy can also be used for taking fetal tissue samples for genetic testing.

It is important to note that while fetoscopy can provide valuable information and treatment options, it does carry some risks, including preterm labor, premature rupture of membranes, infection, and bleeding. Therefore, the decision to undergo fetoscopy should be made carefully, in consultation with a medical professional, and based on a thorough evaluation of the potential benefits and risks.

Quadruplets are defined in medicine as a type of multiple birth where four offspring are produced from the same pregnancy. This occurs when a single fertilized egg divides into four embryos, or more rarely, when four separate eggs are each fertilized by different sperm. Quadruplets face higher risks of preterm birth and other complications compared to singleton pregnancies.

Polyhydramnios is a medical condition characterized by an excessive accumulation of amniotic fluid in the sac surrounding the fetus during pregnancy, typically defined as an amniotic fluid index (AFI) greater than 24 cm or a single deepest pocket (SDP) measurement of more than 8 cm. It occurs in approximately 1-2% of pregnancies and can be associated with various maternal, fetal, and genetic conditions. If left untreated, polyhydramnios may increase the risk of premature labor, premature rupture of membranes, and other pregnancy complications. Proper diagnosis and management are essential to ensure a healthy pregnancy outcome.

I'm not sure I understand your question. "Denmark" is a country located in Northern Europe, and it is not a medical term or concept. It is the southernmost of the Nordic countries, and it consists of the Jutland peninsula and several islands in the Baltic Sea. The capital city of Denmark is Copenhagen.

If you are looking for information about a medical condition that may be associated with Denmark, could you please provide more context or clarify your question? I would be happy to help you with more specific information if I can.

Dermatoglyphics is the study of the fingerprints, palm prints, and other skin ridge patterns found on the hands and feet. These patterns are formed during fetal development and are generally considered to be unique to each individual. Dermatoglyphics can provide important clues about a person's genetic makeup and health status, and they are often used in forensic investigations to help identify individuals. In medicine, dermatoglyphics may be used to help diagnose certain genetic disorders or birth defects.

Genetic predisposition to disease refers to an increased susceptibility or vulnerability to develop a particular illness or condition due to inheriting specific genetic variations or mutations from one's parents. These genetic factors can make it more likely for an individual to develop a certain disease, but it does not guarantee that the person will definitely get the disease. Environmental factors, lifestyle choices, and interactions between genes also play crucial roles in determining if a genetically predisposed person will actually develop the disease. It is essential to understand that having a genetic predisposition only implies a higher risk, not an inevitable outcome.

Assisted reproductive techniques (ART) are medical procedures that involve the handling of human sperm and ova to establish a pregnancy. These techniques are used when other methods of achieving pregnancy have failed or are not available. Examples of ART include in vitro fertilization (IVF), intracytoplasmic sperm injection (ICSI), gamete intrafallopian transfer (GIFT), and zygote intrafallopian transfer (ZIFT). These procedures may be used to treat infertility, prevent genetic disorders, or to help same-sex couples or single people have children. It is important to note that the use of ART can involve significant physical, emotional, and financial costs, and it may not always result in a successful pregnancy.

A phenotype is the physical or biochemical expression of an organism's genes, or the observable traits and characteristics resulting from the interaction of its genetic constitution (genotype) with environmental factors. These characteristics can include appearance, development, behavior, and resistance to disease, among others. Phenotypes can vary widely, even among individuals with identical genotypes, due to differences in environmental influences, gene expression, and genetic interactions.

A twin study is a type of epidemiological study that compares the concordance (similarity) of traits or diseases between monozygotic (identical) and dizygotic (fraternal) twins. The rationale behind this design is that monozygotic twins share 100% of their genetic material, while dizygotic twins share, on average, 50% of their segregating genes - similar to non-twin siblings. By comparing the concordance rates between monozygotic and dizygotic twins, researchers can estimate the heritability (genetic contribution) of a trait or disease.

Twin studies are often used in behavioral genetics, neuroscience, and epidemiology to disentangle genetic and environmental influences on various traits and diseases. However, it is important to note that twin studies have limitations, such as the assumption that environmental factors are equally shared between both types of twins, which may not always be the case.

I'm sorry for any confusion, but "Sweden" is not a medical term. It is a country located in northern Europe. If you have any questions about medical terminology or concepts, I would be happy to help answer those!

Birth order is a term that refers to the sequence in which a person is born in their family, specifically in relation to their siblings. It is used in psychology and sociology to describe the various personality traits, behaviors, and developmental milestones that have been associated with being the firstborn, middle child, youngest child, or an only child.

For example, some studies suggest that firstborn children tend to be more responsible, achievement-oriented, and socially dominant than their younger siblings, while later-born children may be more easygoing, adventurous, and rebellious. However, it's important to note that these patterns are not universal and can be influenced by a variety of factors, including family size, spacing between siblings, gender, parenting style, and individual temperament.

Overall, birth order is just one factor among many that contribute to a person's development and identity, and should not be used as a definitive predictor of their traits or behaviors.

"The McCourty Twins". Tackle Sickle Cell. "Sickle Cell Disease Association of America, Inc. - News & Press". www. ... Devin McCourty and Ryan McCourty - Twins fight Sickle Cell Disease with Tackle Sickle Cell Organization. Kier "Junior" Spates ... Pensacola Sickle Cell Disease Association of Tri-County, Inc. - Orlando Sickle Cell Disease Association of Upper Pinellas/Pasco ... MSCDA) Sickle Cell Disease Association of America, Inc. - Baltimore Greater Boston Sickle Cell Disease Association - Dorchester ...
"Alzheimer's Disease International - GuideStar Profile". www.guidestar.org. Retrieved 2023-02-15. "Twinning Program". Stichting ... Alzheimer's Disease International (24 May 2023). "From Plan to Impact VI: Making every step count". Alzheimer's Disease ... Alzheimer's Disease International (21 September 2023). "ADI Conference". Alzheimer's Disease International (ADI) (CS1 errors: ... Alzheimer's Disease International (ADI) is a not-for-profit, international federation of Alzheimer and dementia associations ...
Pharoah PO, Price TS, Plomin R (September 2002). "Cerebral palsy in twins: a national study". Archives of Disease in Childhood ... with frequent loss or resorption of the other twin(s)." According to Boklage, most twins are born as singles and vanished twins ... A vanishing twin, also known as twin resorption, is a fetus in a multigestation pregnancy that dies in utero and is then ... Online version required free registration) Vanishing twin at eMedicine.com 50 articles about vanishing twin phenomenon in ...
Sukumaran K (March 1991). "Bilateral Norrie's disease in identical twins". The British Journal of Ophthalmology. 75 (3): 179-80 ... Peripheral vascular disease (PVD) has also been associated with Norrie disease. In a study of 56 patients with Norrie disease, ... Norrie disease is a rare disease and genetic disorder that primarily affects the eyes and almost always leads to blindness. It ... Norrie disease is caused by a mutation in the Norrin cystine knot growth factor gene, also known as the Norrie disease ( ...
Tanner CM, Ottman R, Goldman SM, et al (1999). "Parkinson's disease in twins: an etiological study". JAMA 28(1) 341-346. ... 2006). "Symptomatic pharmacological therapy in Parkinson's disease". Parkinson's Disease. London: Royal College of Physicians. ... Parkinson's disease is a degenerative disorder of the central nervous system that results due to the death of dopamine ... Additionally, it has been seen that the intake of animal fats may be linked to the development of the disease. It has also been ...
"Parkinson disease in twins: an etiologic study". JAMA. 281 (4): 341-6. doi:10.1001/jama.281.4.341. PMID 9929087. Langston JW, ... Parkinson's Disease is only experienced by humans but animal testing is essential in drug development. Now Parkinson's Disease ... the etiology of Parkinson's disease, and the development of new strategies to slow or halt disease progression such as cell ... During an interview in 2009 Langston stated: "I would never promise I could solve the disease. What I would do is say, I think ...
Twin Valley Veterinary Health Services". Retrieved 2017-04-06. "NMSU: Sheep Production & Management - White Muscle Disease- ... Commons category link is on Wikidata, Sheep and goat diseases, Bovine diseases, Horse diseases). ... The diseases are characterized by the damage and degeneration of the central nervous system. This disease process is heritable ... Nutritional Muscular Dystrophy (Nutritional Myopathy or White Muscle Disease) is a disease caused by a deficiency of selenium ...
Ballestar E (August 2010). "Epigenetics lessons from twins: prospects for autoimmune disease". Clinical Reviews in Allergy & ... A more recent study, where 114 monozygotic twins and 80 dizygotic twins were analyzed for the DNA methylation status of around ... epigenetic differences in monozygotic twins and implications for twin studies in psychiatry". American Journal of Medical ... Congenital genetic disease is well understood and it is clear that epigenetics can play a role, for example, in the case of ...
This is partly due to a unique disease where she was put into a "standstill", a form of metabolic stasis similar to a coma, for ... Please Twins! (Japanese: おねがい☆ツインズ, Hepburn: Onegai Tsuinzu, Onegai ☆ Twins!) is an anime television series scripted by Yōsuke ... Please Twins! Bandai Channel website (in Japanese) Please Twins! Official US website Archived 2006-06-15 at the Wayback Machine ... One is his twin sister and the other is his first cousin. There is also a CD drama spinoff of the "Onegaiverse" called Onegai ...
Polano died from Alzheimer's disease at age 78; he was diagnosed four years before his death. "Nick Polano - who coached Steve ... ". "Billy Gardner Fired as Manager of the Twins". 22 June 1985 - via LA Times. Greenberg, Jay (23 January 1986). "Seeing The ... Deaths from Alzheimer's disease, Detroit Red Wings coaches, Edmonton Flyers (WHL) players, Hamilton Tiger Cubs players, Hershey ...
Mizukami K, Shiraishi H, Koizumi J; Shiraishi; Koizumi (December 1988). "A Graves' disease of identical twins with mental ... disease (and thyroid disease in general), which are similar to those in patients with organic brain disease. These ... surveyed 250 Graves' disease patients. Of these, 36% were written off sick and 5% even had to take early retirement. In the ... Graves' disease patients can also undergo periods of hypothyroidism (inadequate production of thyroid hormone; see symptoms of ...
Twin and family studies on epigenetics of autoimmune diseases". In Li S, Hopper JL (eds.). Twin and Family Studies of ... play in autoimmune diseases. Autoimmune disorders are a diverse class of diseases that share a common origin. These diseases ... Celiac disease is a disease in which the small intestine is damaged in those whose bodies are unable to process gluten because ... Genome wide it has been shown that when comparing the epigenomes of pairs of identical twins in which one twin is afflicted by ...
True DK, Thomsett M, Liley H, Chitturi S, Cincotta R, Morton A, Cotterill A (September 2007). "Twin pregnancy with a coexisting ... Follow up is necessary in all women with gestational trophoblastic disease, because of the possibility of persistent disease, ... the incidence of rare diseases (such as GTD) is difficult to measure, because epidemiologic data on rare diseases is limited. ... Gestational trophoblastic disease (GTD) is a term used for a group of pregnancy-related tumours. These tumours are rare, and ...
An extreme case of this was seen where monozygotic female twins had extreme variance in expression of Menkes disease (an X- ... "Menkes disease with discordant phenotype in female monozygotic twins". American Journal of Medical Genetics. Part A. 167A (11 ... For example, a female heterozygous for haemophilia (an X-linked disease) would have about half of her liver cells functioning ... Puck JM, Willard HF (January 1998). "X inactivation in females with X-linked disease". The New England Journal of Medicine. 338 ...
Lou Gehrig's Disease), a seizure disorder, Multiple Sclerosis, Crohn's Disease, or a painful terminal illness with less than a ... "Legalize pot? Gov.-elect Tim Walz says Minnesota should". Twin Cities. November 25, 2018. Retrieved April 13, 2019. Reed, Ryan ... "Minnesota medical cannabis program to include PTSD sufferers". Twin Cities. July 5, 2017. Retrieved April 22, 2018. "Medical ... "Minnesota OKs medical cannabis for chronic pain, eye disease". December 2, 2019. Retrieved December 3, 2019. " ...
The breed is highly resistant to disease. Ewes often birth twins, and they have good mothering instincts. This breed is raised ...
Krotz S, Fajardo J, Ghandi S, Patel A, Keith LG (February 2002). "Hypertensive disease in twin pregnancies: a review". Twin ... Center for Disease Control. Archived (PDF) from the original on 19 January 2017. Retrieved 22 September 2016. Engebretson, Joan ... "Smoking During Pregnancy". Center of Disease Control and Prevention. 29 May 2019. Archived from the original on 20 September ... ISBN 978-0-309-05230-6. Centers for Disease Control and Prevention. 2007. Preventing Smoking and Exposure to Secondhand Smoke ...
E. Elizabeth Patton (2021-02-01). "The twin pillars of Disease Models & Mechanisms". Disease Models & Mechanisms. 14 (2). doi: ... including diabetes and obesity Cardiovascular diseases, stroke and hypertension Gastrointestinal diseases Infectious diseases ... "News from DMM , Disease Models & Mechanisms". dmm.biologists.org. Retrieved 2020-04-02. "Aims and scope , Disease Models & ... "Aims and scope , Disease Models & Mechanisms". dmm.biologists.org. Retrieved 2020-02-20. "Aims and scope , Disease Models & ...
Buddhadeb Dasgupta, 77, Indian film director (Bagh Bahadur, Tahader Katha, Uttara) and poet, kidney disease. Peter C. Fishburn ... Mudcat Grant, 85, American baseball player (Cleveland Indians, Minnesota Twins, Oakland Athletics). Haji Gora Haji, 88, ... John Gabriel, 90, American actor (Ryan's Hope, Stagecoach, The Mary Tyler Moore Show), complications from Alzheimer's disease. ... Grace Griffith, 64, American folk and Celtic singer, complications from Parkinson's disease. F. Gerald Ham, 91, American ...
Previously, 'healthy' was seen as the absence of disease indications. Now, 'healthy' patients can be compared to the rest of ... virtual twin), was subsequently called the "digital twin" by John Vickers of NASA in a 2010 Roadmap Report. The digital twin ... digital twin prototype (DTP), digital twin instance (DTI), and digital twin aggregate (DTA). The DTP consists of the designs, ... The digital twin can and does often exist before there is a physical entity. The use of a digital twin in the creation phase ...
Ed Schwartz, 62, American radio personality, kidney and heart disease. Mark Shepherd, 86, American chairman of Texas ... Twins, Indians, Reds), heart attack. Aasiya Zubair, 37, American businesswoman, co-founder of Bridges TV, beheaded. Notable ... Louie Bellson, 84, American jazz drummer, complications from Parkinson's disease. Geoffrey Collin, 87, British army general. ... Howard Zieff, 81, American film director (Private Benjamin), complications from Parkinson's disease. Marie Boas Hall, 89, ...
"UMN named a Udall Center of Excellence in Parkinson's Disease Research". twin-cities.umn.edu. September 22, 2016. Retrieved ... In September 2016, Vitek was appointed Director of the Udall Center of Excellence in Parkinson's Disease Research to improve ... and his current research activities focus on Parkinson's disease, dystonia, tremor and deep brain stimulation. Vitek completed ... began exploring the use of electrical stimulation of precise areas of the brain in order to get rid of Parkinson's disease. He ...
As Chloe's disease progresses, the apartments of Colin, Chick, and Nicholas all begin to decay, and Nicholas suddenly ages ... The Kissitwell Brothers are made up of twins Coriolanus and Pegasus. They work as page-boys at numerous weddings, including ... During her honeymoon, she contracts a water lily in her lung, a rare disease that has only one cure: surrounding the patient ... During the honeymoon, Chloe falls ill with a mysterious disease that primarily consists of coughing and chest pain, and she and ...
It was hoped that cutting it down would prevent Dutch elm disease from spreading to the other twin. In 2008, a cutting of the ... "Historic Preston Park Twin to be felled following elm disease infection". Brighton & Hove City Council. 4 July 2019. Retrieved ... The storm-damaged eastern twin became infected by Dutch elm disease, likely in summer of 2018. It did not show any symptoms of ... "The Preston Twins - and then there was one…". Ancient Tree Forum. "Amsterdam plants a piece of the Preston Twins". Friends of ...
Studies involving twins have shown that schizophrenia is a heritable disease. While no one gene is responsible for the disease ... Dopamine is a monoamine neurotransmitter which is involved in other diseases, such as Parkinson's disease. There is evidence ... Most neurodegenerative diseases produce increased levels of glial cells such as astrocytes, this is not found in schizophrenia ... and that problems during neurodevelopment cause the disease. Traditionally, rodent models of schizophrenia mostly targeted ...
He has examined the relationship between epigenetics and "disease, genetic syndromes, immunity, cardiovascular disease, and ... An example is monozygotic twins. To have a complete picture of what is going on with the epigenetic tapestry of our cells, ... Esteller works in the field of epigenetics of health and disease. Starting from identical genetic sequences, changes in histone ... Epigenetics Editorial Board Wade, Nicholas (5 July 2005). "Explaining Differences in Twins - New York Times". The New York ...
A congenital metabolic disease is also referred to as an inborn error of metabolism. Most of these are single-gene defects, ... This results in conditions such as conjoined twins, and the resulting merged organism may die at birth when it must leave the ... Centers for Disease Control and Prevention. "Facts about Cleft Lip and Cleft Palate , Birth Defects , NCBDDD , CDC". www.cdc. ... Centers for Disease Control and Prevention (CDC) and the National Birth Defects Prevention Network. Archived from the original ...
Junie Donlavey, 90, American Hall of Fame NASCAR team owner (Ken Schrader, Jody Ridley, Donlavey Racing), Alzheimer's disease. ... Bobby Castillo, 59, American baseball player (Los Angeles Dodgers, Minnesota Twins), cancer. Sultanul Kabir Chowdhury, 68, ... David MacLennan, 65, Scottish actor and theatre producer, founded 7:84, motor neurone disease. Chuck Noll, 82, American ... Moise Safra, 79, Syrian-born Brazilian billionaire financier, founder and chairman of Banco Safra, Parkinson's disease. Charles ...
Li, H; Zou, Y; Bao, X; Wang, H; Wang, J; Jin, H; Che, Y; Tang, X (2016). "Monozygotic twins with infantile neuroaxonal ... Alzheimer's disease (AD) Amyotrophic lateral sclerosis (ALS, Lou Gehrig's disease) Cancers Charcot-Marie-Tooth disease (CMT) ... coronary artery disease) and neoplastic diseases (e.g. cancers). Many degenerative diseases exist and some are related to aging ... An example of this is Alzheimer's disease. The other two common groups of degenerative diseases are those that affect ...
"Markers of Viral Infection in Monozygotic Twins Discordant for Chronic Fatigue Syndrome". Clinical Infectious Diseases. 35 (5 ... Systemic Active Infections in Patients with Early Disease". Clinical Infectious Diseases. 31 (4): 894-903. doi:10.1086/318141. ... HHV-6 (and HHV-7) levels in the brain are also elevated in people with Alzheimer's disease. HHV-6B primary infection is the ... HHV-6A includes several adult-derived strains and its disease spectrum is not well defined, although it is thought by some to ...
Re-establishing the regenerative potential is the key to cure these diseases by regenerative medicine. Multipotent stem cells ... Their intrinsic regenerative capacities are disturbed in many hematological and musculoskeletal diseases. ... Blood and bone - conjoined twins in health and disease: bone marrow analogs for hematological and musculoskeletal diseases. ... For this purpose we need to understand the early events of disease onset and progression. Due to the limitations of such ...
The high concordance of premature coronary artery disease found in monozygotic twin pairs may largely be related to factors ... anatomy and the location of coronary lesions in monozygotic and dizygotic twin pairs affected with coronary artery disease. ... With respect to the dominance pattern of coronary blood supply, two of three monozygotic twin pairs differed, while all ... Concordant and discordant locations of stenoses were found with similar frequency in monozygotic and dizygotic twin pairs. ...
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Centers RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.. ...
... passed away after a battle with sickle cell disease. ... The twins shared the news and a photo over their Twitter and ... PHOTO: McCourty Twins Say Goodbye To Aunt Who Lost Battle With Sickle Cell Disease Robert Alvarez ... As many people know, the Tackle Sickle Cell Campaign began from watching our Aunt Winnie fight the sickle cell disease. She ... We will continue our work to bring awareness to this terrible disease. ...
Taylor has launched a season-long home run challenge to support Uplifting Athletes and the rare disease community. Inspired by ... Minnesota Twins Starting Outfielder Michael A. Taylor Runs Home Run Challenge To Support The Rare Disease Community. ... Thats why Minnesota Twins outfielder Michael A. Taylor has launched a season-long home run challenge to support Uplifting ... While this is my first season with the Twins, I am proud to support Uplifting Athletes again so that a brighter future can ...
Quinten Health has announced that it has closed its financing round to advance disease modeling platforms and virtual twins in ... Quinten Health Closes its Financing Round To Advance Disease Modeling Platforms and Virtual Twins in Real-World. Product News ... QUINTEN HEALTH has announced that it has closed its financing round to advance disease modeling platforms and virtual twins in ... We are building reference virtual twin simulators in high priority diseases to accelerate drug development and patient access ...
Markers for cardiovascular disease in monozygotic twins discordant for the use of third-generation oral contraceptives. In: ... Markers for cardiovascular disease in monozygotic twins discordant for the use of third-generation oral contraceptives. Journal ... Markers for cardiovascular disease in monozygotic twins discordant for the use of third-generation oral contraceptives. / Loos ... Markers for cardiovascular disease in monozygotic twins discordant for the use of third-generation oral contraceptives.. Loos ...
Diseases & Conditions Alzheimer Disease Imaging * 2001/viewarticle/defining-difficult-treat-inflammatory-bowel-disease- ... Twin Studies The twin phase 3 studies evaluated the safety and efficacy of gantenerumab in comparison with placebo over 27 ... CAR-T Therapy for NHL Treats Concurrent Rheumatic Disease * Rethinking Approach to Manage Fever in ED for Children With Sickle ... I Forget Names All the Time: Could This Be Alzheimers Disease? * Neuroscientist Alleges Irregularities in Alzheimers Research ...
... twins and is due to arteriovenous anastomosis in the shared placenta. The donor twin is small and anemic. ... Twin-to-twin transfusion syndrome (TTTS) occurs in monochorionic (MC) ... Despite amnioreduction, cardiovascular disease persists and even progresses in many recipient twins. [16, 17] ... encoded search term (Twin-to-Twin Transfusion Syndrome Imaging) and Twin-to-Twin Transfusion Syndrome Imaging What to Read Next ...
Ebola Virus in Breast Milk in an Ebola Virus-Positive Mother with Twin Babies, Guinea, 2015. Emerging Infectious Diseases. 2016 ... Ebola Virus in Breast Milk in an Ebola Virus-Positive Mother with Twin Babies, Guinea, 2015. Emerging Infectious Diseases, 22(4 ... Ebola Virus in Breast Milk in an Ebola Virus-Positive Mother with Twin Babies, Guinea, 2015 On This Page ... When baby 1 became febrile, the woman left her home to seek help from a traditional healer, bringing both twins with her. A few ...
Learn about the remarkable life of original Siamese twins Chang and Ang. ... From: Mysteries at the Museum with Siamese Twins, Assassin Umbrella, Capones Cell ... Learn about the remarkable life of original Siamese twins Chang and Ang. ...
Digital twins have inexhaustible applications in the healthcare industry, from helping researchers to test new scenarios in... ... AIBODY, German Heart Centre Berlin to enhance digital twins research for cardiovascular disease 16.08.2022 ... Medical digital twins: The promise of a new era. Over the years, attempts have been made to define digital twin. There are few ... Applications of Digital Twins in Healthcare. Digital twins have inexhaustible applications in the healthcare industry, from ...
Twin Births Declined 7% During First Year of the Pandemic - Featured Topics from the National Center for Health Statistics ... The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. ... The report "Changes in Twin Births in the United States, 2019-2021" examines changes in the number and rate of twin births from ... The number of twin births in the United States fell by 7% from 2019 to 2020, compared with a 3% decline in the number of ...
... no clear evidence supports delivery of monochorionic twins before 36 weeks. ... Expert review and meta-analysis suggests uncomplicated dichorionic twins should be delivered at 37 weeks gestation; ... Pregnancy Termination Counseling for Lung Disease Requires New Caution * Roe Reversal May Go Well Beyond Abortion ... In dichorionic twins delivered at 37 weeks, the weekly risk for stillbirth with watchful waiting balanced the risk for neonatal ...
Digital twins in health care have begun to help practitioners understand patient conditions, even novel ones such as COVID-19s ... A digital twin is a virtual representation of a physical object or system across its life cycle. It uses real-time data and ... Digital twins in health care have begun to help practitioners understand patient conditions, even novel ones such as COVID-19s ... This highly complex digital model is a counterpart, or twin, of a physical thing, such as a car, a piece of equipment or a ...
Causes of Periodontal Disease Periodontal (gum) disease, which is also known as periodontal disease and periodontitis, is a ... Treatment of Gum Disease. Periodontists specialize in the treatment of gum disease and the placement of dental implants. A ... Here are some of the most common causes of gum disease:. * Poor dental hygiene - Preventing dental disease starts at home with ... Common Causes of Gum Disease. There are genetic and environmental factors involved in the onset of gum disease, and in many ...
Nonetheless, the expanding helper T cells of twins with MS, which were also elevated in non-twin patients with MS, emerged ... In monozygotic twins discordant for multiple sclerosis, the influence of genetic predisposition and environmental factors is ... By integrating data on the immune profiles of healthy monozygotic and dizygotic twin pairs, we estimated the variance in CD25 ... Together, our matched-pair analysis of the extended twin approach allowed us to discern genetically and environmentally ...
With us, we were told Chronic Lung Disease is something our twins would likely outgrow. Sure, they sent us to a pulmonologist ... Our identical twins Tim and Cary were born 11 weeks early after developing Twin to Twin Transfusion Syndrome (TTTS) where one ... When you have twins or more, the chances for that opportunity to sit and wait it out are even higher. ... When you have twin teens to cart around it can feel like a driving service with no tips involved. ...
"The McCourty Twins". Tackle Sickle Cell. "Sickle Cell Disease Association of America, Inc. - News & Press". www. ... Devin McCourty and Ryan McCourty - Twins fight Sickle Cell Disease with Tackle Sickle Cell Organization. Kier "Junior" Spates ... Pensacola Sickle Cell Disease Association of Tri-County, Inc. - Orlando Sickle Cell Disease Association of Upper Pinellas/Pasco ... MSCDA) Sickle Cell Disease Association of America, Inc. - Baltimore Greater Boston Sickle Cell Disease Association - Dorchester ...
... foods of animal origin may help explain why women who eat conventional diets are five times more likely to give birth to twins ... many chronic diseases that are common in Western societies, as well as male reproductive disorders. Milk consumption has even ... Mechanisms of Twinning VII Effect of Diet and Heredity on the Human Twinning Rate. J Reprod Med. 2006 May;51(5):405-10.. ... Mechanisms of Twinning VII Effect of Diet and Heredity on the Human Twinning Rate. J Reprod Med. 2006 May;51(5):405-10.. ...
... of smoking and alcohol consumption on cancer and cardiovascular diseases whilst controlling for genetic propensity to disease. ... The Swedish Twin Registry (STR), which today has developed into a unique resource, was first established in the late 1950s to ... The Swedish Twin Registry: a unique resource for clinical, epidemiological and genetic studies J Intern Med. 2002 Sep;252(3): ... The Swedish Twin Registry (STR), which today has developed into a unique resource, was first established in the late 1950s to ...
Hospitalization for respiratory syncytial virus bronchiolitis and disease severity in twins. Miri Dotan*, Liat Ashkenazi- ... Hospitalization for respiratory syncytial virus bronchiolitis and disease severity in twins. Israel Medical Association Journal ... Hospitalization for respiratory syncytial virus bronchiolitis and disease severity in twins. In: Israel Medical Association ... Hospitalization for respiratory syncytial virus bronchiolitis and disease severity in twins. / Dotan, Miri; Ashkenazi-Hoffnung ...
Modeling Disease Progression in Mild Cognitive Impairment and Alzheimers Disease with Digital Twins. ... Evaluating Digital Twins for Alzheimers Disease using Data from a Completed Phase 2 Clinical Trial. Read more ... Evaluating Digital Twins for Alzheimers Disease using Data from a Completed Phase 2 Clinical Trial. Read more ...
A disease of ewes in late pregnancy. Early treatment is essential. ... Ewes carrying twins are more often affected, but ewes carrying single lambs can also get the disease. In Tasmania the crucial ...
... environment in susceptibility to breast cancer and to give an estimate of heritability in the propensity to develop the disease ... environment in susceptibility to breast cancer and to give an estimate of heritability in the propensity to develop the disease ... The heritability of breast cancer: a Bayesian correlated frailty model applied to Swedish twins data Twin Res. 2004 Apr;7(2): ... We used the special information coming from twin data, particularly breast cancer data, from the Swedish Twin Register. The ...
Team Hope Walk- Twin Cities. DATE: 9/30/23 10AM. LOCATION: Hyland Lake Park 10145 E Bush Lake Rd, Bloomington, MN 55438. LINK: ... Huntingtons Disease Patient and Family Symposium. DATE: 10/14/2023 8:30 AM. LOCATION: The Alloy King of Prussia (Doubletree ... Pittsburgh Huntingtons Disease Patient, Family and Caregiver Education Day. DATE: 4/22/2023 10:00 AM. LOCATION: Shadyside ... Huntingtons disease (HD) is a fatal genetic disorder that causes the progressive breakdown of nerve cells in the brain. It ...
De Vos-Thijssen Vector Borne Diseases Fund * Back. Scholarships * Paul Speijer Fund ... Digital Twin for water management; Sjoerd Boersma (WUR). *A Digital Twin for the development of the rural area; Ilona Kemerling ... WDCC Meetup: How to use Digital Twins in green life sciences?. Digital Twins are one of the key enabling technologies that can ... Digital Twins offer opportunities to make timely data driven decisions for a better future. In recent years, WUR has carried ...
Twins. Reside at same LTCF. Both experiencing homelessness. Sex and age. Male, 15 yrs; female, 56 yrs. Female, 59 yrs; male, 32 ... Clusters of unencapsulated Hi disease were defined as cases of invasive NTHi disease in the same county that occurred ≤14 days ... Abbreviations: ACVD = atherosclerotic cardiovascular disease; COPD = chronic obstructive pulmonary disease; LTCF = long-term ... of invasive Hi disease in 2018. However, invasive disease caused by non-b Hi, particularly serotype a (Hia) and NTHi, has been ...
Virtual patients, digital twins and causal disease models: Paving the ground for in silico clinical trials. Drug Discov Today. ...
Neurotwins, digital twins of human brains. How to combat neurological disease by means of virtual representations of the human ... As soon as early scholars began to understand that the brain might be related to disease, attempts to change brain states began ... s disease. These as well as other contemporary works of art dialogue with top scientific experiments made by research groups in ... treatments that offer unexpected ways of finding answers for brain diseases. ...
  • Alaska Airlines flight attendant Jenny Stansel, 38, has been battling chronic kidney disease for more than 15 years. (insideedition.com)
  • Digital twins have inexhaustible applications in the healthcare industry, from helping researchers to test new scenarios in real-life environments with improved safety and cost-effectiveness to allowing the creation of useful virtual models and medical simulations based on the gathered data from patient records, wearable devices, device manufacturers, drugs and pharmaceutical companies, and other healthcare departments. (med-tech.world)
  • Using digital twins, cardiothoracic surgeons and neurosurgeons can run a virtual simulation of surgical procedures before executing complex surgeries. (med-tech.world)
  • Digital twins can simulate how molecules and proteins interact to identify the right therapeutics and enlist digital cohorts of patients testing new drugs with optimal dosage to reduce the number of clinical trials needed. (med-tech.world)
  • Digital twins also provide an avenue for the digital design of medical devices to be tested with different patients under different conditions in virtual worlds where there's a low cost of failure. (med-tech.world)
  • Digital twins in health care have begun to help practitioners understand patient conditions, even novel ones such as COVID-19's impact on the lungs. (advmfg.org)
  • WDCC Meetup: How to use Digital Twins in green life sciences? (wur.nl)
  • Digital Twins are one of the key enabling technologies that can help us improve quality of life. (wur.nl)
  • Digital Twins offer opportunities to make timely data driven decisions for a better future. (wur.nl)
  • In recent years, WUR has carried out an investment programme to discover how we can use Digital Twins in green life sciences. (wur.nl)
  • That is why we continue to do research and to develop Digital Twins together with partners. (wur.nl)
  • In the future, we will be able to create digital twins that simulate various processes in our body. (medicalxpress.com)
  • Digital twins are virtual representations of devices and processes that capture the physical properties of the environment and operational algorithms/techniques in the context of medical devices and technologies. (medicalxpress.com)
  • An international team of researchers have developed advanced computer models, or "digital twins," of diseases, with the goal of improving diagnosis and treatment. (medicalxpress.com)
  • Over the weekend, Jason and Devin McCourty announced sad news that that their aunt, Winifred, passed away after a battle with sickle cell disease. (patsfans.com)
  • As many people know, the Tackle Sickle Cell Campaign began from watching our Aunt Winnie fight the sickle cell disease. (patsfans.com)
  • The Sickle Cell Disease Association of America, Inc. (SCDAA) is a nonprofit organization with the sole purpose of supporting research, education and funding of individuals, families those who are impacted by sickle cell disease. (wikipedia.org)
  • To advocate for and enhance our membership's ability to improve the quality of health, life and services for individuals, families and communities affected by sickle cell disease and related conditions, while promoting the search for a cure for all people in the world with sickle cell disease. (wikipedia.org)
  • The Sickle Cell Disease Association of America, Inc. originated in Racine, Wisconsin. (wikipedia.org)
  • There was a common belief that there was a need for national attention to sickle cell disease. (wikipedia.org)
  • The name was changed in 1994 to the Sickle Cell Disease Association of America, Inc. Over the course of several years, the organization has grown into over 40 different branches. (wikipedia.org)
  • Research Public Health Education Professional Health Education Patient Services Community Services Support to Global Organizations and Practitioners The Sickle Cell Disease Association of America, Inc. hosts several events throughout each year. (wikipedia.org)
  • The Sickle Cell Disease National Convention is held annually during the first weekend of October in Baltimore's Inner Harbor. (wikipedia.org)
  • Tiki Barber - The former NFL running back has sickle cell disease and does his part educating others. (wikipedia.org)
  • Devin McCourty and Ryan McCourty - Twins fight Sickle Cell Disease with Tackle Sickle Cell Organization. (wikipedia.org)
  • Santonio Holmes - Runs benefit for son with sickle cell disease. (wikipedia.org)
  • Sickle Cell Disease Association of America Inc. "Premium Domain Names at already Discounted Prices - sicklecellnationalwalk.com is available for sale! (wikipedia.org)
  • The investigational anti-amyloid monoclonal antibody gantenerumab (Genentech/Roche) showed no clear benefit for patients with early Alzheimer's disease (AD) in the phase 3 GRADUATE I and II trials, the company has announced. (medscape.com)
  • It plans to present topline data from the trials in a presentation scheduled for November 30 during the upcoming Clinical Trials on Alzheimer's Disease conference. (medscape.com)
  • We know that current anti-amyloid approaches are not a cure, nor will they stop the disease on their own, but they are the first wave of effective treatments for Alzheimer's, with more to come," the Alzheimer's Association said. (medscape.com)
  • The results we've seen from drugs in this class point to the urgent need to bring a range of amyloid and nonamyloid therapies to market to slow the course of Alzheimer's disease," said Fillit. (medscape.com)
  • Successes and disappointments are an expected part of the scientific process, but we are unmistakably in a modern era of Alzheimer's research, on the cusp of a new generation of therapies that will take a more holistic approach to treating the disease by targeting all of its underlying causes," Fillit said. (medscape.com)
  • Parkinson's disease is the world's second most common neurodegenerative disorder, behind Alzheimer's disease . (yahoo.com)
  • The Journal of Alzheimer's Disease is an international multidisciplinary journal to facilitate progress in understanding the etiology, pathogenesis, epidemiology, genetics, behavior, treatment and psychology of Alzheimer's disease. (medicalxpress.com)
  • The journal is dedicated to providing an open forum for original research that will expedite our fundamental understanding of Alzheimer's disease. (medicalxpress.com)
  • Suddenly getting lost, failing to recognize family members, or forgetting words and names are well-known symptoms of Alzheimer's disease. (medicalxpress.com)
  • Mild cognitive impairment (MCI) is a form of cognitive ability loss that can precede Alzheimer's disease or other types of dementia. (medicalxpress.com)
  • Alzheimer's disease is a progressive neurodegenerative disease estimated to affect 6 million Americans and 33 million people worldwide. (medicalxpress.com)
  • Could something as basic as a good night's sleep protect African Americans who have a gene variant linked to Alzheimer's Disease? (medicalxpress.com)
  • The three common alleles at the APOE locus influence the onset and lifetime risk of typical late-onset Alzheimer's disease (AD). (johnshopkins.edu)
  • Meyer, JM & Breitner, JCS 1998, ' Multiple threshold model for the onset of Alzheimer's disease in the NAS-NRC twin panel ', American Journal of Medical Genetics - Neuropsychiatric Genetics , vol. 81, no. 1, pp. 92-97. (johnshopkins.edu)
  • Breitner, John C.S. / Multiple threshold model for the onset of Alzheimer's disease in the NAS-NRC twin panel . (johnshopkins.edu)
  • Our disease models leverage from the leading data networks/platforms and combine the best from AI/ML, predictive modeling, and pharmaco-epidemiology. (technologynetworks.com)
  • Given this changing epidemiology, U.S. surveillance data were reviewed to investigate secondary cases of invasive disease caused by Hi. (cdc.gov)
  • The Chinese National Twin Registry: A Unique Data Source for Systems Epidemiology of Complex Disease ( Twin Res hum Genet. (lu.se)
  • The SMFM also recommends fetal echocardiography in monochorionic diamniotic (MCDA) twin gestations due to increased risk of congenital heart disease in this population, especially in gestations with TTTS, which negatively affects the recipient twin's heart. (medscape.com)
  • AIBODY , a Physiology-as-a-Service platform, and German Heart Centre Berlin (DHZB), a medical research institute specializing in cardiovascular disease, have signed a collaboration agreement which focuses on the development of a suite of solutions to improve the diagnosis and treatment of congenital heart disease. (med-tech.world)
  • There are genetic and environmental factors involved in the onset of gum disease, and in many cases the risk of developing periodontitis can be significantly lowered by taking preventative measures. (elisondentistry.com)
  • Genetic predisposition - Despite practicing rigorous oral hygiene routines, as much as 30% of the population may have a strong genetic predisposition to gum disease. (elisondentistry.com)
  • These individuals are six times more likely to develop periodontal disease than individuals with no genetic predisposition. (elisondentistry.com)
  • Here we investigated the peripheral immune signatures of 61 monozygotic twin pairs discordant for MS to dissect the influence of genetic predisposition and environmental factors. (nature.com)
  • By integrating data on the immune profiles of healthy monozygotic and dizygotic twin pairs, we estimated the variance in CD25 expression by helper T cells displaying a naive phenotype to be largely driven by genetic and shared early environmental influences. (nature.com)
  • Nonetheless, the expanding helper T cells of twins with MS, which were also elevated in non-twin patients with MS, emerged independent of the individual genetic makeup. (nature.com)
  • Hence, investigating how genetic predisposition and environmental triggers shape the interactions of individual immune cells is vital to understand the pathophysiology of autoimmune diseases including MS. (nature.com)
  • Here we conducted an in-depth pairwise analysis of the systemic immune compartment of 61 monozygotic twin pairs discordant for MS, in which both siblings carry the same genetic and early-life environmental risk for the disease, yet only one is affected by MS. This approach thus eliminated the majority of bias attributed to variable genetic and early environmental influences in a heterogenous population 17 , 18 . (nature.com)
  • The Swedish Twin Registry (STR), which today has developed into a unique resource, was first established in the late 1950s to study the importance of smoking and alcohol consumption on cancer and cardiovascular diseases whilst controlling for genetic propensity to disease. (nih.gov)
  • Huntington's disease (HD) is a fatal genetic disorder that causes the progressive breakdown of nerve cells in the brain. (hdsa.org)
  • The twins' curiosity about Oliver's on-screen illness - an incurable genetic condition that affects one baby born every day in the UK - moved their real life mum, Lia, to find out more about the disease, leading to the idea of a fancy dress fundraiser. (thelilyfoundation.org.uk)
  • The heritability was 0.57 (95% CI, 0.45-0.69) amongst male twins, and 0.38 (0.26-0.50) amongst female twins.The genetic contribution to the variation in CHD-mortality was moderate both in females and males. (duke.edu)
  • Given the limited numbers of AD cases now available, models containing only additive genetic or shared environmental effects (explaining 75% and 65% of individual differences in disease onset, respectively) cannot be rejected in favor of a model that retains both influences. (johnshopkins.edu)
  • What's more, the discovery of the Lupski family mutation, a genetic variant that hadn't previously been connected to CMT disease, may allow for new directions in medical research, and could potentially lead to new treatments for the disease down the line. (discovermagazine.com)
  • In 2011, whole-genome sequencing revealed not only the genetic variants responsible, it also revealed which neurotransmitters were affected, and suggested a new drug regimen that worked remarkably well to control the twins' symptoms. (discovermagazine.com)
  • The Australian Twin Registry as a resource for genetic studies into ophthalmic traits (Twin Res Hum Genet. (lu.se)
  • Chinese National Twin Registry as a resource for genetic epidemiologic studies of common and complex diseases in China ( Twin Res. (lu.se)
  • OBJECTIVE To compare the coronary anatomy and the location of coronary lesions in monozygotic and dizygotic twin pairs affected with coronary artery disease. (bmj.com)
  • RESULTS The lumen diameters of the left main coronary artery, the left anterior descending coronary artery, the circumflex artery, and the right coronary artery, as well as the lengths of the left main coronary artery, showed similar variability within monozygotic and dizygotic twin pairs. (bmj.com)
  • Concordant and discordant locations of stenoses were found with similar frequency in monozygotic and dizygotic twin pairs. (bmj.com)
  • In MZ pairs discordant for IWL, co-twins with at least one IWL were 0.4 kg m −2 ( P =0.041) heavier at 25 years than their non-dieting co-twins (no differences in baseline BMIs). (nature.com)
  • The application of a correlated log-normal frailty model leads to a very large estimate of the population heterogeneity (sigma = 6.7), and relatively small correlations between co-twins' frailties - around 0.3 for monozygotic and 0.1 for dizygotic twins. (nih.gov)
  • Their intrinsic regenerative capacities are disturbed in many hematological and musculoskeletal diseases. (europa.eu)
  • Due to the limitations of such studies in human beings and animals, I propose to develop human in vitro models of healthy bone marrow, which can be induced to develop hematological and musculoskeletal diseases with high incidence, namely leukemia, multiple myeloma and bone metastasis. (europa.eu)
  • The topics covered include infectious diseases, many cancers, chronic and acute physical and psychological conditions, newly emerging and reemerging diseases, public health issues, and issues of interest to the young adult audience (eating disorders, sports injuries, growth, and puberty). (gale.com)
  • Disorders affecting TWINS, one or both, at any age. (bvsalud.org)
  • Field clinicians working during the unprecedented Ebola virus disease (EVD) outbreak in West Africa, which began in December 2013, have been confronted with complex situations concerning mothers and breast-fed children in which one or both in a pair have tested positive for Ebola virus (EBOV) ( 1 ). (cdc.gov)
  • For testing of Sexually Transmitted Diseases, do not urinate for one hour before testing. (plannedparenthood.org)
  • I. 'Street of twins': multiple births in Cuba II. (lu.se)
  • Twins, triplets, and other multiples often are admitted to the NICU. (chkd.org)
  • The high concordance of premature coronary artery disease found in monozygotic twin pairs may largely be related to factors that are independent of the macroanatomic distribution of the coronary blood supply. (bmj.com)
  • [ 3 ] After birth, premature infants may need to undergo transcranial ultrasonography, as premature twins are susceptible to intraventricular hemorrhage and periventricular leukomalacia. (medscape.com)
  • We are building reference 'virtual twin' simulators in high priority diseases to accelerate drug development and patient access to the drugs they really need" commented Dr Billy Amzal, CEO of QUINTEN HEALTH and a pioneer expert in disease modeling since 1999. (technologynetworks.com)
  • Since 1999, the Huntington's Disease Society of America has committed more than $20 million to fund research, with the goal of finding effective treatments to slow Huntington's disease. (hdsa.org)
  • Following an average annual decline of 2% from 2014 to 2019, the number of twin births fell by 7% from 2019 to 2020 and increased by 2% from 2020 to 2021. (cdc.gov)
  • The report " Changes in Twin Births in the United States, 2019-2021 " examines changes in the number and rate of twin births from 2019 to 2021 by month and year of birth and age and race and Hispanic origin of the mother. (cdc.gov)
  • The number of twin births in the United States fell by 7% from 2019 to 2020, compared with a 3% decline in the number of singleton births. (cdc.gov)
  • The twin birth rate from 2019 to 2020 declined by 11% for women aged 40 and over, 5% for those aged 30-39, and 1% for females under age 30. (cdc.gov)
  • What are the symptoms of Parkinson's disease and how can it be treated? (yahoo.com)
  • So what are the symptoms of Parkinson's disease and how can it be treated? (yahoo.com)
  • The main symptoms of Parkinson's disease include involuntary shaking (otherwise known as tremors), movement that's slower than usual and stiffness in the muscles, the NHS outlines . (yahoo.com)
  • For more information about the symptoms of Parkinson's disease, visit the NHS here . (yahoo.com)
  • However, for every one in 20 people affected by the disease, symptoms may appear when they're under the age of 40. (yahoo.com)
  • While there is no known cure for Parkinson's disease, symptoms may be controlled through treatment. (yahoo.com)
  • While drug treatment may help to manage Parkinson's symptoms, it cannot slow the progression of the disease. (yahoo.com)
  • With no symptoms, he was shocked to learn that the disease had advanced to stage-4, the tumours had spread in his lungs, his adrenal gland, kidney, and pancreas. (albertacancer.ca)
  • It is therefore not surprising that the earliest use of the term 'digital twin' appeared in 1994 in the field of medical imaging. (med-tech.world)
  • By month, the twin birth rate declined by 7% in January 2021 compared with the year before and generally remained stable until the end of the year, when rates increased by 7% in November and 14% in December. (cdc.gov)
  • Centers for Disease Control and Prevention. (cdc.gov)
  • Some of the organization's partnerships include: National Association for the Advancement of Colored People (NAACP), National Institutes of Health (NIH), Health Resources and Services Administration (HRSA), Centers for Disease Control (CDC), United Way of America, and the Robert Johnson Foundation. (wikipedia.org)
  • The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. (cdc.gov)
  • When an individual is suffering from gum disease, the additional destruction of gingival tissue due to grinding can accelerate the progression of the disease. (elisondentistry.com)
  • A periodontist can perform effective cleaning procedures in deep pockets such as scaling and root planing, and also prescribe antibiotic and antifungal medications to treat infection and halt the progression of the disease. (elisondentistry.com)
  • Studies in humans have shown that men and women whose birth weights were at the lower end of the normal range, who were thin or short at birth, or who were small in relation to placental size have increased rates of coronary heart disease. (bmj.com)
  • Twin-to-twin transfusion syndrome (TTTS) is a common complication that typically presents in the second trimester of pregnancy in 10-15% of monochorionic (MC) twins due to net transfer of volume and hormonal substances from 1 twin to the other across vascular anastomoses on the placenta. (medscape.com)
  • In uncomplicated dichorionic twin pregnancies, delivery should be considered at 37 weeks' gestation to minimize perinatal death, and no clear evidence supports delivery of monochorionic twins before 36 weeks, according to a meta-analysis published online September 6 in the BMJ . (medscape.com)
  • Then they performed a meta-analysis to evaluate the risk for stillbirth and neonatal complications in weekly intervals for monochorionic and dichorionic twin pregnancies, starting from 34 weeks' gestation. (medscape.com)
  • Timing of delivery for multiple pregnancies should be always be individualised, however, the current evidence-base suggests that in uncomplicated dichorionic twin pregnancies delivery should be considered at 37 weeks' gestation and in monochorionic pregnancies delivery should be considered from 36 weeks," he continued. (medscape.com)
  • A retrospective cohort study of MCDA twin pregnancies complicated by TTTS that underwent laser coagulation of vascular anastomoses or fetal reduction by umbilical cord occlusion found that the prevalence of brain lesions detected by third-trimester MRI is higher than that of prenatal ultrasonography alone, making MRI a useful adjunct to detect antenatal brain lesions in twin pregnancies after in utero treatment for TTTS. (medscape.com)
  • Our study provides comprehensive estimates comparing risks of stillbirth and neonatal mortality at various gestational ages, which is required for the planning of delivery in uncomplicated twin pregnancies," write Fiona Cheong-See, MBBS, from Queen Mary University of London, United Kingdom, and colleagues with the Global Obstetrics Network Collaboration. (medscape.com)
  • The study is the largest to date to evaluate stillbirths and neonatal outcomes in twin pregnancies, and the first to estimate neonatal morbidity for specific gestational ages. (medscape.com)
  • Twin pregnancies carry a higher risk for stillbirth than singleton pregnancies, and the risk increases with gestational age. (medscape.com)
  • Although uncomplicated twin pregnancies are often scheduled for early delivery to prevent stillbirth, preterm birth can increase neonatal complications. (medscape.com)
  • Yet, the optimal age for delivery of twin pregnancies has not been established. (medscape.com)
  • Our estimates of fetal and neonatal outcomes at various gestational ages in twin pregnancies should be taken into account when decisions are made on timing of delivery," the authors conclude. (medscape.com)
  • The information on risks provided in twin pregnancies will complement the ongoing national and international efforts to reduce the rates of stillbirths and unexpected neonatal complications in babies born near term. (medscape.com)
  • We welcome this robust systematic review which provides us with a comprehensive picture on stillbirths and neonatal outcomes in twin pregnancies," said Mark Kilby, MD, professor of Fetal Medicine and spokesperson for the Royal College of Obstetricians and Gynaecologists, in a related press release. (medscape.com)
  • The study confirms existing findings of previous studies and adds further objectivity to the NICE guidelines on the management of twin pregnancies. (medscape.com)
  • Because twin pregnancies are risky pregnancies. (nutritionfacts.org)
  • Background: Respiratory syncytial virus (RSV) is a common cause of lower respiratory tract disease and hospitalization in infants and young children. (tau.ac.il)
  • results: Twins comprised 7.6% (66/875) of hospitalized infants with RSV bronchiolitis during the study period. (tau.ac.il)
  • Infants who have GBS disease can require prolonged hospitalization and expensive supportive therapy, and survivors may suffer permanent disability (e.g., hearing or visual loss or mental retardation). (cdc.gov)
  • The aim of this study was to determine whether the use of third-generation OC has an impact on markers of CV disease in genetically identical women. (maastrichtuniversity.nl)
  • Use of third-generation OC impacts on CV disease markers in young-adult genetically identical women. (maastrichtuniversity.nl)
  • Real-life identical twins, not the kind they make movies about. (latimes.com)
  • Naturally, it was the same surgical team that had performed the same operation on the same bone of the same hand of identical twin Ozzie, in the same hospital. (latimes.com)
  • except identical twins. (cdc.gov)
  • In studies of identical twins, researchers from Lund University have identified mechanisms that could be behind the development of type 2 diabetes. (lu.se)
  • This could explain cases where one identical twin develops type 2 diabetes while the other remains healthy. (lu.se)
  • The study involved 14 pairs of identical twins in Sweden and. (lu.se)
  • conclusions: Our findings suggest that twins hospitalized with RSV bronchiolitis do not have an increased risk for severe infection as compared to singletons. (tau.ac.il)
  • Despite this triad of clinical findings, patients with anti-GBM disease may present with a spectrum of conditions ranging from pulmonary hemorrhage with minimal or no renal involvement to full-blown renal failure with limited or no pulmonary involvement. (medscape.com)
  • The Cuban Twin Registry: initial findings and perspectives ( Twin Res Hum Genet. (lu.se)
  • For instance, when an AI-powered anatomical analysis is combined with the virtual model of a patient's heart, it enables researchers to understand the progression of heart diseases over time and to identify how the patient will respond to new drugs. (med-tech.world)
  • 359 disease terms (MeSH) has been reported with BDNF gene. (cdc.gov)
  • With respect to the dominance pattern of coronary blood supply, two of three monozygotic twin pairs differed, while all dizygotic twin pairs were concordant. (bmj.com)
  • The fetal origins hypothesis states that fetal undernutrition in middle to late gestation, which leads to disproportionate fetal growth, programmes later coronary heart disease. (bmj.com)
  • The programming of blood pressure, insulin responses to glucose, cholesterol metabolism, blood coagulation, and hormonal settings are all areas of active research.The BMJ's recent editorial on the fetal origins hypothesis stated that it rests only on the "very general" proposition that fetal undernutrition causes coronary heart disease. (bmj.com)
  • The hypothesis states that coronary heart disease is associated with specific patterns of disproportionate fetal growth that result from fetal undernutrition in middle to late gestation. (bmj.com)
  • The early epidemiological studies that pointed to the possible importance of programming in coronary heart disease were based on the simple strategy of examining men and women in middle and late life whose body measurements at birth were recorded. (bmj.com)
  • Scholars@Duke publication: Heritability of death from coronary heart disease: a 36-year follow-up of 20 966 Swedish twins. (duke.edu)
  • BACKGROUND: Kawasaki disease is a systemic vasculitis that affects small and medium-sized vessels, primarily the coronary arteries. (bvsalud.org)
  • The aim of this study was to investigate the role of genes and environment in susceptibility to breast cancer and to give an estimate of heritability in the propensity to develop the disease. (nih.gov)
  • QUINTEN HEALTH has announced that it has closed its financing round to advance disease modeling platforms and virtual twins in real-world, as part of the Quinten Group's €14 million growth equity investment from TECHLIFE CAPITAL and MACSF, essentially dedicated to the healthcare activities of the Quinten group. (technologynetworks.com)
  • The funds will be used to advance QUINTEN HEALTH's in silico disease and care simulation platform, turning a decade of experience in disease modeling and real-world data analytics into regulatory-grade disease cohort simulators to accelerate, de-risk and maximize the value of pharmaceutical R&D. QUINTEN HEALTH's disease models are developed from the global federation of best-in-class real-world and trial data sources. (technologynetworks.com)
  • Coding of occupation for the "young cohort" of the Danish twin register. (lu.se)
  • A You will not directly benefit but these studies may genes are helping us learn about many diseases and health eventually help the health of people in the future. (cdc.gov)
  • Using complementary multimodal high-throughput and high-dimensional single-cell technologies in conjunction with data-driven computational tools, we identified an inflammatory shift in a monocyte cluster of twins with MS, coupled with the emergence of a population of IL-2 hyper-responsive transitional naive helper T cells as MS-related immune alterations. (nature.com)
  • Inflammatory diseases like rheumatoid arthritis have complex disease mechanisms that can differ from patient to patient with the same diagnosis. (medicalxpress.com)
  • OBJECTIVE: Kawasaki Disease (KD) is the leading cause of acquired heart disease in children in developed countries (e.g. (bvsalud.org)
  • CASE REPORT: A 5-year-old female was diagnosed with classic Kawasaki disease. (bvsalud.org)
  • CONCLUSIONS: The use of etanercept in Kawasaki disease has demonstrated a clinically favorable response. (bvsalud.org)
  • Widespread vaccination has reduced invasive disease caused by Haemophilus influenzae (Hi) type b in the United States by approximately 99%, but incidence of disease caused by non-type b Hi has been increasing. (cdc.gov)
  • Since licensure and recommendation for Hib vaccines were implemented, the incidence of invasive Hib disease in the United States has declined by approximately 99%, accounting for only 1.3% of invasive Hi disease in 2018. (cdc.gov)
  • However, despite clinical trials that demonstrate the effectiveness of intrapartum antibiotic prophylaxis, prevention strategies have not been implemented widely or consistently, and the incidence of neonatal GBS disease has not declined. (cdc.gov)
  • Armenia has very high cancer incidence and mortality rates relative to other countries, as well as a very high prevalence of rare malignant diseases. (who.int)
  • For this purpose we need to understand the early events of disease onset and progression. (europa.eu)
  • Diabetes and underlying medical issues - Many medical conditions can intensify or accelerate the onset and progression of gum disease including respiratory disease, heart disease, arthritis and osteoporosis. (elisondentistry.com)
  • Traditional methods are not appropriate for this estimation since they do not consider right-censoring (incomplete expression of the genotype owing to death) nor do they model the relation of onset age and disease liability. (johnshopkins.edu)
  • Prognosis varies depending on disease stage and severity and gestational age at diagnosis. (medscape.com)
  • In contrast, the mere fact of a child being a twin was not found to be a significant risk factor for disease severity. (tau.ac.il)
  • Conversely, a registry-based study investigated the familial recurrence rate of MS and revealed that monozygotic twin pairs displayed the highest familial risk (17% age-adjusted risk for the unaffected twin) of developing MS, indicating a strong heritable effect 8 . (nature.com)
  • Since that time, the Registry has been expanded and updated on several occasions, and the focus has similarly broadened to most common complex diseases. (nih.gov)
  • The model is fitted to the occurrence of AD among 9,786 members of the National Academy of Sciences-National Research Council Registry of aging veteran twins. (johnshopkins.edu)
  • Australian Twin Registry: 30 years of progress (Twin Res Hum Genet. (lu.se)
  • The introduction of the Australian twin registry (in Chinese) ( Zhonghua Liu Xing Bing Xue Za Zhi. (lu.se)
  • Australian Twin Registry: a nationally funded resource for medical and scientific research, incorporating match and WATCH (Twin Res Hum Genet. (lu.se)
  • The Australian Twin Registry (Twin Res. (lu.se)
  • Australian NHMRC Twin Registry: a resource for pediatric research (Pediatr Cardiol. (lu.se)
  • Australian N.H. & M.R.C. Twin Registry (Aust N Z J Med. (lu.se)
  • Australian NHMRC twin registry (Med J Aust. (lu.se)
  • The Brazilian Twin Registry (Twin Res Hum Genet. (lu.se)
  • Brazilian Twin Registry: A Bright Future for Twin Studies/Twin Research (Twin Res Hum Genet. (lu.se)
  • Chilean school-age children twin registry: planning, sampling and implications ( Twin Res Hum Genet. (lu.se)
  • The Chinese National Twin Registry: a 'gold mine' for scientific research ( J Intern Med. (lu.se)
  • The Chinese National Twin Registry: an update ( Twin Res hum Genet. (lu.se)
  • Current status of the Chinese National Twin Registry ( Twin Res Hum Genet. (lu.se)
  • The Qingdao Twin Registry: a status update ( Twin Res hum Genet. (lu.se)
  • The Qingdao Twin Registry: a focus on chronic disease research ( Twin Res Hum Genet. (lu.se)
  • The Danish Twin Registry: An Updated Overview ( Twin Res Hum Genet. (lu.se)
  • The Danish Twin Registry: linking surveys, national registers, and biological information ( Twin Res Hum Genet. (lu.se)
  • The Danish Twin Registry (Scand J Public Health. (lu.se)
  • The Danish Twin Registry in the new millennium ( Twin Res Hum Genet. (lu.se)
  • The danish twin registry: past and present ( Twin Res. (lu.se)
  • The Danish Twin Registry: 127 birth cohorts of twins ( Twin Res. (lu.se)
  • The early history of the Danish twin registry (in Danish) ( Dan Medicinhist Arbog. (lu.se)
  • Analysis of monozygotic twin pairs from the National Longitudinal Study of Adolescent Health (Add Health) revealed that between-twin differences in IQ have little effect on the majority of the examined outcome measures. (bvsalud.org)
  • Even during this COVID-19 pandemic, digital twin technology has been employed to optimize the usage of ventilators, reduce person-to-person contact, support contact contactless temperature scanning, and prevent the risk of disease transmission. (med-tech.world)
  • This is a challenging time for charities, and the Covid-19 pandemic has left people with mitochondrial diseases more vulnerable than ever. (thelilyfoundation.org.uk)
  • mRNA-based vaccines and gene/cell therapeutics open up new possibilities for medical practitioners in the fight against cancer and infectious or hereditary diseases. (medicalxpress.com)
  • Chronic stress and poor diet - Stress lowers the ability of the immune system to fight off disease, which means bacterial infections may possibly beat the body's defense system. (elisondentistry.com)
  • Diabetes is a complex disease. (lu.se)
  • This report provides the epidemiologic basis for prevention protocols, summarizes results of clinical trials demonstrating the efficacy of intrapartum antimicrobial agents, examines limitations of different approaches to prevention, and presents guidelines for the prevention of GBS disease. (cdc.gov)
  • CDC developed these GBS disease prevention guidelines through critical analysis of clinical trial data and subsequent review of guidelines by consultants representing numerous disciplines. (cdc.gov)
  • Goodpasture's name has been used in a more specific clinical condition known as Goodpasture disease, which is the pulmonary renal syndrome specifically associated with anti-glomerular basement membrane (anti-GBM) antibodies. (medscape.com)
  • On the basis of this clinical report, Goodpasture's name is often linked to the pulmonary renal syndrome of alveolar hemorrhage and necrotizing and proliferative glomerulonephritis, although vasculitis and not anti-GBM disease is believed to be the cause of the pulmonary renal syndrome in Goodpasture's original patient. (medscape.com)
  • The twin phase 3 studies evaluated the safety and efficacy of gantenerumab in comparison with placebo over 27 months for 1965 adults from 30 countries. (medscape.com)
  • Doppler studies of the umbilical artery, umbilical vein, and ductus venosus in each twin help establish staging once TTTS has been diagnosed. (medscape.com)
  • A Most studies using DNA samples will simply add to our knowledge of health and disease. (cdc.gov)
  • The results of continuing studies of your stored specimens may help find new ways to prevent, treat, and cure many diseases. (cdc.gov)
  • High Hib vaccination coverage since the 1990s has substantially reduced Hib disease, and other serotypes now account for most Hi-associated invasive disease in the United States ( 3 ). (cdc.gov)