A group of glucose polymers made by certain bacteria. Dextrans are used therapeutically as plasma volume expanders and anticoagulants. They are also commonly used in biological experimentation and in industry for a wide variety of purposes.
Long-chain polymer of glucose containing 17-20% sulfur. It has been used as an anticoagulant and also has been shown to inhibit the binding of HIV-1 to CD4-POSITIVE T-LYMPHOCYTES. It is commonly used as both an experimental and clinical laboratory reagent and has been investigated for use as an antiviral agent, in the treatment of hypolipidemia, and for the prevention of free radical damage, among other applications.
A complex of ferric oxyhydroxide with dextrans of 5000 to 7000 daltons in a viscous solution containing 50 mg/ml of iron. It is supplied as a parenteral preparation and is used as a hematinic. (Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p1292)
Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER.
Dextranase is an enzyme that catalyzes the hydrolysis of dextran, a glucose polymer, into smaller oligosaccharides or simple sugars, primarily used in clinical settings to prevent or treat dextran-induced complications such as anaphylaxis and renal dysfunction.
Fluorescent probe capable of being conjugated to tissue and proteins. It is used as a label in fluorescent antibody staining procedures as well as protein- and amino acid-binding techniques.
Used as a support for ion-exchange chromatography.
The segment of LARGE INTESTINE between the CECUM and the RECTUM. It includes the ASCENDING COLON; the TRANSVERSE COLON; the DESCENDING COLON; and the SIGMOID COLON.
A genus of gram-positive, facultatively anaerobic bacteria whose growth is dependent on the presence of a fermentable carbohydrate. It is nonpathogenic to plants and animals, including humans.
Lining of the INTESTINES, consisting of an inner EPITHELIUM, a middle LAMINA PROPRIA, and an outer MUSCULARIS MUCOSAE. In the SMALL INTESTINE, the mucosa is characterized by a series of folds and abundance of absorptive cells (ENTEROCYTES) with MICROVILLI.
The property of blood capillary ENDOTHELIUM that allows for the selective exchange of substances between the blood and surrounding tissues and through membranous barriers such as the BLOOD-AIR BARRIER; BLOOD-AQUEOUS BARRIER; BLOOD-BRAIN BARRIER; BLOOD-NERVE BARRIER; BLOOD-RETINAL BARRIER; and BLOOD-TESTIS BARRIER. Small lipid-soluble molecules such as carbon dioxide and oxygen move freely by diffusion. Water and water-soluble molecules cannot pass through the endothelial walls and are dependent on microscopic pores. These pores show narrow areas (TIGHT JUNCTIONS) which may limit large molecule movement.
Any liquid used to replace blood plasma, usually a saline solution, often with serum albumins, dextrans or other preparations. These substances do not enhance the oxygen- carrying capacity of blood, but merely replace the volume. They are also used to treat dehydration.
Abnormal accumulation of fluid in tissues of any part of the LARYNX, commonly associated with laryngeal injuries and allergic reactions.
Property of membranes and other structures to permit passage of light, heat, gases, liquids, metabolites, and mineral ions.
A disorder in which the adductor muscles of the VOCAL CORDS exhibit increased activity leading to laryngeal spasm. Laryngismus causes closure of the VOCAL FOLDS and airflow obstruction during inspiration.
Reduction of blood viscosity usually by the addition of cell free solutions. Used clinically (1) in states of impaired microcirculation, (2) for replacement of intraoperative blood loss without homologous blood transfusion, and (3) in cardiopulmonary bypass and hypothermia.
The formation of clumps of RED BLOOD CELLS under low or non-flow conditions, resulting from the attraction forces between the red blood cells. The cells adhere to each other in rouleaux aggregates. Slight mechanical force, such as occurs in the circulation, is enough to disperse these aggregates. Stronger or weaker than normal aggregation may result from a variety of effects in the ERYTHROCYTE MEMBRANE or in BLOOD PLASMA. The degree of aggregation is affected by ERYTHROCYTE DEFORMABILITY, erythrocyte membrane sialylation, masking of negative surface charge by plasma proteins, etc. BLOOD VISCOSITY and the ERYTHROCYTE SEDIMENTATION RATE are affected by the amount of erythrocyte aggregation and are parameters used to measure the aggregation.
Agents that emit light after excitation by light. The wave length of the emitted light is usually longer than that of the incident light. Fluorochromes are substances that cause fluorescence in other substances, i.e., dyes used to mark or label other compounds with fluorescent tags.
A sucrose polymer of high molecular weight.
Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.
Inbred C57BL mice are a strain of laboratory mice that have been produced by many generations of brother-sister matings, resulting in a high degree of genetic uniformity and homozygosity, making them widely used for biomedical research, including studies on genetics, immunology, cancer, and neuroscience.
The sum of the weight of all the atoms in a molecule.
A family of spiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one derivatives. These are used as dyes, as indicators for various metals, and as fluorescent labels in immunoassays.
A highly acidic mucopolysaccharide formed of equal parts of sulfated D-glucosamine and D-glucuronic acid with sulfaminic bridges. The molecular weight ranges from six to twenty thousand. Heparin occurs in and is obtained from liver, lung, mast cells, etc., of vertebrates. Its function is unknown, but it is used to prevent blood clotting in vivo and vitro, in the form of many different salts.

Effect of intravenous dextran 70 and pneumatic leg compression on incidence of postoperative pulmonary embolism. (1/2888)

The incidence of pulmonary embolism and deep vein thrombosis was measured in 50 matched pairs of patients undergoing common surgical procedures with preoperative and postoperative ventilation-perfusion lung scans and the fibrinogen uptake test. One patient in each pair was treated with intravenous dextran 70 and pneumatic leggings. The incidence of pulmonary embolism among the treated patients was significantly reduced from 24% to 8%, but the incidence of deep vein thrombosis was not significantly reduced (34% to 24%).  (+info)

Reduction in baroreflex cardiovascular responses due to venous infusion in the rabbit. (2/2888)

We studied reflex bradycardia and depression of mean arterial blood pressure (MAP) during left aortic nerve (LAN) stimulation before and after volume infusion in the anesthetized rabbit. Step increases in mean right atrial pressure (MRAP) to 10 mm Hg did not result in a significant change in heart rate or MAP. After volume loading, responses to LAN stimulation were not as great and the degree of attenuation was propoetional to the level of increased MRAP. A change in responsiveness was observed after elevation of MRAP by only 1 mm Hg, corresponding to less than a 10% increase in average calculated blood volume. after an increase in MRAP of 10 mm Hg, peak responses were attenuated by 44% (heart rate) and 52% (MAP), and the initial slopes (rate of change) were reduced by 46% (heart rate) and 66% (MAP). Comparison of the responses after infusion with blood and dextran solutions indicated that hemodilution was an unlikely explanation for the attenuation of the reflex responses. Total arterial baroreceptor denervation (ABD) abolished the volume-related attenuation was still present following bilateral aortic nerve section or vagotomy. It thus appears that the carotid sinus responds to changes inblood volume and influences the reflex cardiovascular responses to afferent stimulation of the LAN. On the other hand, cardiopulmonary receptors subserved by vagal afferents do not appear to be involved.  (+info)

Interaction of inflammatory cells and oral microorganisms. II. Modulation of rabbit polymorphonuclear leukocyte hydrolase release by polysaccharides in response to Streptococcus mutans and Streptococcus sanguis. (3/2888)

The release of lysosomal hydrolases from polymorphonuclear leukocytes (PMNs) has been postulated in the pathogenesis of tissue injury in periodontal disease. In the present study, lysosomal enzyme release was monitored from rabbit peritoneal exudate PMNs exposed to Streptocccus mutans or Streptococcus sanguis. S. mutans grown in brain heart infusion (BHI) broth failed to promote significant PMN enzyme release. S. sanguis grown in BHI broth, although more effective than S. mutants, was a weak stimulus for promotion of PMN hydrolase release. Preincubation of washed, viable S. mutans in sucrose or in different-molecular-weight dextrans resulted in the ability of the organisms to provoke PMN release reactions. This effect could bot be demonstrated with boiled or trypsinized S. mutans or with viable S. sanguis. However, when grown in BHI broth supplemented with sucrose, but not with glucose, both S. mutans and S. sanguis triggered discharge of PMN enzymes. The mechanism(s) whereby dextran or sucrose modulates PMN-bacterial interaction may in some manner be related to promotion of microbial adhesiveness or aggregation by dextran and by bacterial synthesis of glucans from sucrose.  (+info)

Glomerular size-selective dysfunction in NIDDM is not ameliorated by ACE inhibition or by calcium channel blockade. (4/2888)

BACKGROUND: In patients with insulin-dependent diabetes mellitus (IDDM) and overt nephropathy glomerular barrier size-selectivity progressively deteriorates with time and is effectively improved by angiotensin converting enzyme (ACE) inhibition. Whether similar glomerular functional changes develop in proteinuric patients with non-insulin-dependent diabetes mellitus (NIDDM), and whether antihypertensive agents can favorably affect glomerular filtration of macromolecules in these patients, has not been documented yet. METHODS: We investigated renal hemodynamics and fractional clearance of neutral dextrans of graded sizes, in nine proteinuric patients with NIDDM and renal biopsy findings of typical diabetic glomerulopathy. Six healthy volunteers served as controls. We also investigated the effects of an ACE inhibitor and of a calcium channel blocker, both given in doses targeted to achieve a comparable level of systemic blood pressure control, on glomerular hemodynamics and sieving function. Theoretical analysis of glomerular macromolecule transport was adopted to evaluate intrinsic glomerular membrane permeability properties. RESULTS: Fractional clearance of large macromolecules (42 to 66 A in radius) was significantly higher in diabetic patients than in controls, and the distribution of membrane pore radii was calculated to be shifted towards larger pore sizes in diabetics (mean radius increased from 55 to 60 A). Despite effective blood pressure control, neither antihypertensive affected glomerular hemodynamics to any significant extent. Fractional clearance of dextrans, as well as of albumin and IgG, and total urinary proteins were not modified by either treatments. CONCLUSIONS: These data indicate that patients with NIDDM and overt nephropathy develop abnormalities in size-selective function of the glomerular barrier and, at variance to IDDM, such changes were not ameliorated either by ACE inhibition or calcium channel blockade.  (+info)

Poly(L-lysine)-graft-dextran copolymer promotes pyrimidine motif triplex DNA formation at physiological pH. Thermodynamic and kinetic studies. (5/2888)

Extreme instability of pyrimidine motif triplex DNA at physiological pH severely limits its use for artificial control of gene expression in vivo. Stabilization of the pyrimidine motif triplex at physiological pH is therefore of great importance in improving its therapeutic potential. To this end, isothermal titration calorimetry interaction analysis system and electrophoretic mobility shift assay have been used to explore the thermodynamic and kinetic effects of our previously reported triplex stabilizer, poly (L-lysine)-graft-dextran (PLL-g-Dex) copolymer, on pyrimidine motif triplex formation at physiological pH. Both the thermodynamic and kinetic analyses have clearly indicated that in the presence of the PLL-g-Dex copolymer, the binding constant of the pyrimidine motif triplex formation at physiological pH was about 100 times higher than that observed without any triplex stabilizer. Of importance, the triplex-promoting efficiency of the copolymer was more than 20 times higher than that of physiological concentrations of spermine, a putative intracellular triplex stabilizer. Kinetic data have also demonstrated that the observed copolymer-mediated promotion of the triplex formation at physiological pH resulted from the considerable increase in the association rate constant rather than the decrease in the dissociation rate constant. Our results certainly support the idea that the PLL-g-Dex copolymer could be a key material and may eventually lead to progress in therapeutic applications of the antigene strategy in vivo.  (+info)

Polymer structure and solubility of deoxyhemoglobin S in the presence of high concentrations of volume-excluding 70-kDa dextran. Effects of non-s hemoglobins and inhibitors. (6/2888)

Earlier observations indicated that volume exclusion by admixed non-hemoglobin macromolecules lowered the polymer solubility ("Csat") of deoxyhemoglobin (Hb) S, presumably by increasing its activity. In view of the potential usefulness of these observations for in vitro studies of sickling-related polymerization, we examined the ultrastructure, solubility behavior, and phase distributions of deoxygenated mixtures of Hb S with 70-kDa dextran, a relatively inert, low ionic strength space-filling macromolecule. Increasing admixture of dextran progressively lowered the Csat of deoxyHb S. With 12 g/dl dextran, a 5-fold decrease in apparent Csat ("dextran-Csat") was obtained together with acceptable sensitivity and proportionality with the standard Csat when assessing the effects of non-S Hb admixtures (A, C, and F) or polymerization inhibitors (alkylureas or phenylalanine). The volume fraction of dextran excluding Hb was 70-75% of total deoxyHb-dextran (12 g/dl) volumes. Electron microscopy showed polymer fibers and fiber-to-crystal transitions indistinguishable from those formed without dextran. Thus when Hb quantities are limited, as with genetically engineered recombinant Hbs or transgenic sickle mice, the dextran-Csat provides convenient and reliable screening of effects of Hb S modifications on polymerization under near-physiological conditions, avoiding problems of high ionic strength.  (+info)

Cytokine-mediated inflammatory hyperalgesia limited by interleukin-4. (7/2888)

1. The effect of IL-4 on responses to intraplantar (i.pl.) carrageenin, bradykinin, TNFalpha, IL-1beta, IL-8 and PGE2 was investigated in a model of mechanical hyperalgesia in rats. Also, the cellular source of the IL-4 was investigated. 2. IL-4, 30 min before the stimulus, inhibited responses to carrageenin, bradykinin, and TNFalpha, but not responses to IL-1beta, IL-8 and PGE2. 3. IL-4, 2 h before the injection of IL-1beta, did not affect the response to IL-1beta, whereas IL-4, 12 or 12+2 h before the IL-1beta, inhibited the hyperalgesia (-30%, -74%, respectively). 4. In murine peritoneal macrophages, murine IL-4 for 2 h before stimulation with LPS, inhibited (-40%) the production of IL-1beta but not PGE2. Murine IL-4 (for 16 h before stimulation with LPS) inhibited LPS-stimulated PGE2 but not IL-1beta. 5. Anti-murine IL-4 antibodies potentiated responses to carrageenin, bradykinin and TNFalpha, but not IL-1beta and IL-8, as well as responses to bradykinin in athymic rats but not in rats depleted of mast cells with compound 40/80. 6. These data suggest that IL-4 released by mast cells limits inflammatory hyperalgesia. During the early phase of the inflammatory response the mode of action of the IL-4 appears to be inhibition of the production TNFalpha, IL-1beta and IL-8. In the later phase of the response, in addition to inhibiting the production of pro-inflammatory cytokines, IL-4 also may inhibit the release of PGs.  (+info)

Heterogeneity in the ability of cytotoxic murine NK cell clones to enhance Ig secretion in vitro. (8/2888)

We recently described a panel of cytotoxic murine NK cell clones that also enhanced Ig secretion by B cells activated in an in vitro model of T cell-independent type 2 (TI-2) responses. We employed dextran-conjugated anti-IgD (alphadelta-dex) as a model antigen. Here we study the mechanism of Ig induction by these clones. Addition of the various NK clones to sort-purified B cells stimulated with alphadelta-dex and IL-2 resulted in a markedly heterogeneous increase in Ig secretion, which varied from 3-fold, as mediated by clone PKO 56, to 15-fold, as induced by clone PKO 101. The other NK cells showed intermediate levels of Ig induction. Furthermore, while addition of as few as 0.04% of PKO 101 cells stimulated significant increases and 1% induced near maximum Ig production, a 3% addition of PKO 56 cells was required for significant enhancement of Ig secretion. Supernatant material collected from the NK clones mediated Ig production at levels that mirrored the induction by the corresponding cells. Cytokine analysis showed that while all members of the NK panel produced IFN-gamma only two secreted granulocyte macrophage colony stimulating factor and that the levels of Ig induction mediated by the NK clones correlated only with their levels of IFN-gamma secretion. Culture of B and NK cells in the presence of anti-IFN-gamma demonstrated that IFN-gamma was the critical cytokine in NK-induced Ig production. These findings establish heterogeneity in the ability of NK cells to increase Ig secretion in vitro and show that NK-produced IFN-gamma is an important factor in determining this heterogeneity.  (+info)

Dextrans are a type of complex glucose polymers that are formed by the action of certain bacteria on sucrose. They are branched polysaccharides consisting of linear chains of α-1,6 linked D-glucopyranosyl units with occasional α-1,3 branches.

Dextrans have a wide range of applications in medicine and industry. In medicine, dextrans are used as plasma substitutes, volume expanders, and anticoagulants. They are also used as carriers for drugs and diagnostic agents, and in the manufacture of immunoadsorbents for the removal of toxins and pathogens from blood.

Dextrans can be derived from various bacterial sources, but the most common commercial source is Leuconostoc mesenteroides B-512(F) or L. dextranicum. The molecular weight of dextrans can vary widely, ranging from a few thousand to several million Daltons, depending on the method of preparation and purification.

Dextrans are generally biocompatible and non-toxic, but they can cause allergic reactions in some individuals. Therefore, their use as medical products requires careful monitoring and testing for safety and efficacy.

Dextran sulfate is a type of polysaccharide (a complex carbohydrate) that is made up of repeating units of the sugar dextran, which has been sulfonated (introduced with a sulfonic acid group). It is commonly used as a molecular weight standard in laboratory research and can also be found in some medical products.

In medicine, dextran sulfate is often used as a treatment for hemodialysis patients to prevent the formation of blood clots in the dialyzer circuit. It works by binding to and inhibiting the activity of certain clotting factors in the blood. Dextran sulfate may also have anti-inflammatory effects, and it has been studied as a potential treatment for conditions such as inflammatory bowel disease and hepatitis.

It is important to note that dextran sulfate can have side effects, including allergic reactions, low blood pressure, and bleeding. It should be used under the close supervision of a healthcare professional.

Iron-dextran complex is a parenteral preparation used as an iron supplement to treat or prevent iron deficiency anemia in patients who cannot take oral iron or do not respond well to oral iron therapy. The complex is formed by combining iron salts with dextran, a type of polysaccharide derived from cornstarch, which acts as a carrier and helps increase the solubility and stability of the iron.

The iron-dextran complex is available in various forms, including injectable solutions and intravenous (IV) infusions. It works by releasing iron ions slowly into the body, where they can be taken up by red blood cell precursors in the bone marrow and used to synthesize hemoglobin, a protein that carries oxygen in the blood.

It is important to note that iron-dextran complex can cause anaphylactic reactions in some individuals, so it should be administered with caution and under medical supervision. Patients should be monitored for signs of allergic reactions during and after administration, and appropriate measures should be taken if necessary.

Colitis is a medical term that refers to inflammation of the inner lining of the colon or large intestine. The condition can cause symptoms such as diarrhea, abdominal cramps, and urgency to have a bowel movement. Colitis can be caused by a variety of factors, including infections, inflammatory bowel disease (such as Crohn's disease or ulcerative colitis), microscopic colitis, ischemic colitis, and radiation therapy. The specific symptoms and treatment options for colitis may vary depending on the underlying cause.

Dextranase is an enzyme that breaks down dextran, a type of complex sugar (polysaccharide) consisting of many glucose molecules linked together in a chain. Dextran is produced by certain bacteria and can be found in some foods, as well as in the body during infections or after surgery. Dextranase is used medically to help prevent or treat complications associated with dextran, such as blockages in blood vessels caused by the accumulation of dextran molecules. It may also be used in research and industry for various purposes, including the production of clarified fruit juices and wine.

Fluorescein-5-isothiocyanate (FITC) is not a medical term per se, but a chemical compound commonly used in biomedical research and clinical diagnostics. Therefore, I will provide a general definition of this term:

Fluorescein-5-isothiocyanate (FITC) is a fluorescent dye with an absorption maximum at approximately 492-495 nm and an emission maximum at around 518-525 nm. It is widely used as a labeling reagent for various biological molecules, such as antibodies, proteins, and nucleic acids, to study their structure, function, and interactions in techniques like flow cytometry, immunofluorescence microscopy, and western blotting. The isothiocyanate group (-N=C=S) in the FITC molecule reacts with primary amines (-NH2) present in biological molecules to form a stable thiourea bond, enabling specific labeling of target molecules for detection and analysis.

DEAE-Dextran is a water-soluble polymer that is often used in biochemistry and molecular biology research. The acronym "DEAE" stands for diethylaminoethyl, which is a type of charged group that can bind to and interact with negatively charged molecules such as DNA. Dextran is a type of sugar polymer that makes the DEAE groups more soluble in water.

In research settings, DEAE-Dextran is commonly used to precipitate DNA or to create complexes with DNA that can be used for various purposes, such as transfection (the process of introducing genetic material into cells). The positive charge of the DEAE groups allows them to interact strongly with the negative charges on the DNA molecule, forming a stable complex that can be taken up by cells.

It's important to note that DEAE-Dextran is not used in clinical medicine, but rather as a research tool in laboratory settings.

The colon, also known as the large intestine, is a part of the digestive system in humans and other vertebrates. It is an organ that eliminates waste from the body and is located between the small intestine and the rectum. The main function of the colon is to absorb water and electrolytes from digested food, forming and storing feces until they are eliminated through the anus.

The colon is divided into several regions, including the cecum, ascending colon, transverse colon, descending colon, sigmoid colon, rectum, and anus. The walls of the colon contain a layer of muscle that helps to move waste material through the organ by a process called peristalsis.

The inner surface of the colon is lined with mucous membrane, which secretes mucus to lubricate the passage of feces. The colon also contains a large population of bacteria, known as the gut microbiota, which play an important role in digestion and immunity.

Leuconostoc is a genus of gram-positive, facultatively anaerobic bacteria that belong to the family Leuconostocaceae. These bacteria are non-motile, non-spore forming, and occur as pairs or chains. They are catalase-negative and reduce nitrate to nitrite.

Leuconostoc species are commonly found in nature, particularly in plants, dairy products, and fermented foods. They play a significant role in the food industry, where they are used in the production of various fermented foods such as sauerkraut, pickles, and certain cheeses.

In clinical settings, Leuconostoc species can sometimes be associated with healthcare-associated infections, particularly in patients who have underlying medical conditions or who are immunocompromised. They can cause bacteremia, endocarditis, and device-related infections. However, these infections are relatively rare, and the majority of Leuconostoc species are considered to be non-pathogenic.

The intestinal mucosa is the innermost layer of the intestines, which comes into direct contact with digested food and microbes. It is a specialized epithelial tissue that plays crucial roles in nutrient absorption, barrier function, and immune defense. The intestinal mucosa is composed of several cell types, including absorptive enterocytes, mucus-secreting goblet cells, hormone-producing enteroendocrine cells, and immune cells such as lymphocytes and macrophages.

The surface of the intestinal mucosa is covered by a single layer of epithelial cells, which are joined together by tight junctions to form a protective barrier against harmful substances and microorganisms. This barrier also allows for the selective absorption of nutrients into the bloodstream. The intestinal mucosa also contains numerous lymphoid follicles, known as Peyer's patches, which are involved in immune surveillance and defense against pathogens.

In addition to its role in absorption and immunity, the intestinal mucosa is also capable of producing hormones that regulate digestion and metabolism. Dysfunction of the intestinal mucosa can lead to various gastrointestinal disorders, such as inflammatory bowel disease, celiac disease, and food allergies.

Capillary permeability refers to the ability of substances to pass through the walls of capillaries, which are the smallest blood vessels in the body. These tiny vessels connect the arterioles and venules, allowing for the exchange of nutrients, waste products, and gases between the blood and the surrounding tissues.

The capillary wall is composed of a single layer of endothelial cells that are held together by tight junctions. The permeability of these walls varies depending on the size and charge of the molecules attempting to pass through. Small, uncharged molecules such as water, oxygen, and carbon dioxide can easily diffuse through the capillary wall, while larger or charged molecules such as proteins and large ions have more difficulty passing through.

Increased capillary permeability can occur in response to inflammation, infection, or injury, allowing larger molecules and immune cells to enter the surrounding tissues. This can lead to swelling (edema) and tissue damage if not controlled. Decreased capillary permeability, on the other hand, can lead to impaired nutrient exchange and tissue hypoxia.

Overall, the permeability of capillaries is a critical factor in maintaining the health and function of tissues throughout the body.

Plasma substitutes are fluids that are used to replace the plasma volume in conditions such as hypovolemia (low blood volume) or plasma loss, for example due to severe burns, trauma, or major surgery. They do not contain cells or clotting factors, but they help to maintain intravascular volume and tissue perfusion. Plasma substitutes can be divided into two main categories: crystalloids and colloids.

Crystalloid solutions contain small molecules that can easily move between intracellular and extracellular spaces. Examples include normal saline (0.9% sodium chloride) and lactated Ringer's solution. They are less expensive and have a lower risk of allergic reactions compared to colloids, but they may require larger volumes to achieve the same effect due to their rapid distribution in the body.

Colloid solutions contain larger molecules that tend to stay within the intravascular space for longer periods, thus increasing the oncotic pressure and helping to maintain fluid balance. Examples include albumin, fresh frozen plasma, and synthetic colloids such as hydroxyethyl starch (HES) and gelatin. Colloids may be more effective in restoring intravascular volume, but they carry a higher risk of allergic reactions and anaphylaxis, and some types have been associated with adverse effects such as kidney injury and coagulopathy.

The choice of plasma substitute depends on various factors, including the patient's clinical condition, the underlying cause of plasma loss, and any contraindications or potential side effects of the available products. It is important to monitor the patient's hemodynamic status, electrolyte balance, and coagulation profile during and after the administration of plasma substitutes to ensure appropriate resuscitation and avoid complications.

Laryngeal edema is a medical condition characterized by the swelling of the tissues in the larynx or voice box. The larynx, which contains the vocal cords, plays a crucial role in protecting the airways, regulating ventilation, and enabling speech and swallowing. Laryngeal edema can result from various causes, such as allergic reactions, infections, irritants, trauma, or underlying medical conditions like angioedema or autoimmune disorders.

The swelling of the laryngeal tissues can lead to narrowing of the airways, causing symptoms like difficulty breathing, noisy breathing (stridor), coughing, and hoarseness. In severe cases, laryngeal edema may obstruct the airway, leading to respiratory distress or even suffocation. Immediate medical attention is necessary for individuals experiencing these symptoms to ensure proper diagnosis and timely intervention. Treatment options typically include medications like corticosteroids, antihistamines, or epinephrine to reduce swelling and alleviate airway obstruction.

In the context of medicine and physiology, permeability refers to the ability of a tissue or membrane to allow the passage of fluids, solutes, or gases. It is often used to describe the property of the capillary walls, which control the exchange of substances between the blood and the surrounding tissues.

The permeability of a membrane can be influenced by various factors, including its molecular structure, charge, and the size of the molecules attempting to pass through it. A more permeable membrane allows for easier passage of substances, while a less permeable membrane restricts the movement of substances.

In some cases, changes in permeability can have significant consequences for health. For example, increased permeability of the blood-brain barrier (a specialized type of capillary that regulates the passage of substances into the brain) has been implicated in a number of neurological conditions, including multiple sclerosis, Alzheimer's disease, and traumatic brain injury.

Laryngospasm, often mistakenly referred to as "laryngismus," is a medical condition characterized by an involuntary and sustained closure of the vocal cords (the structures that form the larynx or voice box). This spasm can occur in response to various stimuli, such as irritation, aspiration, or emotional distress, leading to difficulty breathing, coughing, and stridor (a high-pitched sound during inspiration).

The term "laryngismus" is not a widely accepted medical term; however, it may be used informally to refer to any condition affecting the larynx. The correct term for a prolonged or chronic issue with the larynx would be "laryngeal dyskinesia."

Hemodilution is a medical term that refers to the reduction in the concentration of certain components in the blood, usually referring to red blood cells (RBCs) or hemoglobin. This occurs when an individual's plasma volume expands due to the infusion of intravenous fluids or the body's own production of fluid, such as during severe infection or inflammation. As a result, the number of RBCs per unit of blood decreases, leading to a lower hematocrit and hemoglobin level. It is important to note that while hemodilution reduces the concentration of RBCs in the blood, it does not necessarily indicate anemia or blood loss.

Erythrocyte aggregation, also known as rouleaux formation, is the clumping together of red blood cells (erythrocytes) in a way that resembles a stack of coins. This phenomenon is typically observed under low-shear conditions, such as those found in small blood vessels and capillaries.

The aggregation of erythrocytes is influenced by several factors, including the concentration of plasma proteins, the charge and shape of the red blood cells, and the flow characteristics of the blood. One of the most important proteins involved in this process is fibrinogen, a large plasma protein that can bridge between adjacent red blood cells and cause them to stick together.

Erythrocyte aggregation can have significant effects on blood flow and rheology (the study of how blood flows), particularly in diseases such as diabetes, sickle cell disease, and certain types of anemia. Increased erythrocyte aggregation can lead to reduced oxygen delivery to tissues, increased blood viscosity, and impaired microcirculatory flow, all of which can contribute to tissue damage and organ dysfunction.

Fluorescent dyes are substances that emit light upon excitation by absorbing light of a shorter wavelength. In a medical context, these dyes are often used in various diagnostic tests and procedures to highlight or mark certain structures or substances within the body. For example, fluorescent dyes may be used in imaging techniques such as fluorescence microscopy or fluorescence angiography to help visualize cells, tissues, or blood vessels. These dyes can also be used in flow cytometry to identify and sort specific types of cells. The choice of fluorescent dye depends on the specific application and the desired properties, such as excitation and emission spectra, quantum yield, and photostability.

Ficoll is not a medical term itself, but it is a type of synthetic polymer that is often used in laboratory settings for various medical and scientific purposes. Ficoll is a high-molecular-weight coopolymer of sucrose and epichlorohydrin, which forms a highly flexible and soluble structure with unique physical properties.

In medicine and research, Ficoll is commonly used as a component in density gradient media for the separation and purification of biological cells, viruses, and other particles based on their size, density, or sedimentation rate. The most common application of Ficoll is in the preparation of peripheral blood mononuclear cells (PBMCs) from whole blood samples.

Ficoll-Paque is a commercially available density gradient medium that contains Ficoll and a high-density solution of sodium diatrizoate. When a blood sample is layered onto the Ficoll-Paque solution and centrifuged, the various cell types in the blood separate into distinct bands based on their densities. The PBMCs, which include lymphocytes, monocytes, and other immune cells, collect at the interface between the Ficoll layer and the plasma layer, allowing for easy isolation and further analysis.

Therefore, while not a medical term itself, Ficoll plays an essential role in many laboratory procedures used in medical research and diagnostics.

Animal disease models are specialized animals, typically rodents such as mice or rats, that have been genetically engineered or exposed to certain conditions to develop symptoms and physiological changes similar to those seen in human diseases. These models are used in medical research to study the pathophysiology of diseases, identify potential therapeutic targets, test drug efficacy and safety, and understand disease mechanisms.

The genetic modifications can include knockout or knock-in mutations, transgenic expression of specific genes, or RNA interference techniques. The animals may also be exposed to environmental factors such as chemicals, radiation, or infectious agents to induce the disease state.

Examples of animal disease models include:

1. Mouse models of cancer: Genetically engineered mice that develop various types of tumors, allowing researchers to study cancer initiation, progression, and metastasis.
2. Alzheimer's disease models: Transgenic mice expressing mutant human genes associated with Alzheimer's disease, which exhibit amyloid plaque formation and cognitive decline.
3. Diabetes models: Obese and diabetic mouse strains like the NOD (non-obese diabetic) or db/db mice, used to study the development of type 1 and type 2 diabetes, respectively.
4. Cardiovascular disease models: Atherosclerosis-prone mice, such as ApoE-deficient or LDLR-deficient mice, that develop plaque buildup in their arteries when fed a high-fat diet.
5. Inflammatory bowel disease models: Mice with genetic mutations affecting intestinal barrier function and immune response, such as IL-10 knockout or SAMP1/YitFc mice, which develop colitis.

Animal disease models are essential tools in preclinical research, but it is important to recognize their limitations. Differences between species can affect the translatability of results from animal studies to human patients. Therefore, researchers must carefully consider the choice of model and interpret findings cautiously when applying them to human diseases.

C57BL/6 (C57 Black 6) is an inbred strain of laboratory mouse that is widely used in biomedical research. The term "inbred" refers to a strain of animals where matings have been carried out between siblings or other closely related individuals for many generations, resulting in a population that is highly homozygous at most genetic loci.

The C57BL/6 strain was established in 1920 by crossing a female mouse from the dilute brown (DBA) strain with a male mouse from the black strain. The resulting offspring were then interbred for many generations to create the inbred C57BL/6 strain.

C57BL/6 mice are known for their robust health, longevity, and ease of handling, making them a popular choice for researchers. They have been used in a wide range of biomedical research areas, including studies of cancer, immunology, neuroscience, cardiovascular disease, and metabolism.

One of the most notable features of the C57BL/6 strain is its sensitivity to certain genetic modifications, such as the introduction of mutations that lead to obesity or impaired glucose tolerance. This has made it a valuable tool for studying the genetic basis of complex diseases and traits.

Overall, the C57BL/6 inbred mouse strain is an important model organism in biomedical research, providing a valuable resource for understanding the genetic and molecular mechanisms underlying human health and disease.

Molecular weight, also known as molecular mass, is the mass of a molecule. It is expressed in units of atomic mass units (amu) or daltons (Da). Molecular weight is calculated by adding up the atomic weights of each atom in a molecule. It is a useful property in chemistry and biology, as it can be used to determine the concentration of a substance in a solution, or to calculate the amount of a substance that will react with another in a chemical reaction.

Fluorescein is not a medical condition, but rather a diagnostic dye that is used in various medical tests and procedures. It is a fluorescent compound that absorbs light at one wavelength and emits light at another wavelength, which makes it useful for imaging and detecting various conditions.

In ophthalmology, fluorescein is commonly used in eye examinations to evaluate the health of the cornea, conjunctiva, and anterior chamber of the eye. A fluorescein dye is applied to the surface of the eye, and then the eye is examined under a blue light. The dye highlights any damage or abnormalities on the surface of the eye, such as scratches, ulcers, or inflammation.

Fluorescein is also used in angiography, a medical imaging technique used to examine blood vessels in the body. A fluorescein dye is injected into a vein, and then a special camera takes pictures of the dye as it flows through the blood vessels. This can help doctors diagnose and monitor conditions such as cancer, diabetes, and macular degeneration.

Overall, fluorescein is a valuable diagnostic tool that helps medical professionals detect and monitor various conditions in the body.

Heparin is defined as a highly sulfated glycosaminoglycan (a type of polysaccharide) that is widely present in many tissues, but is most commonly derived from the mucosal tissues of mammalian lungs or intestinal mucosa. It is an anticoagulant that acts as an inhibitor of several enzymes involved in the blood coagulation cascade, primarily by activating antithrombin III which then neutralizes thrombin and other clotting factors.

Heparin is used medically to prevent and treat thromboembolic disorders such as deep vein thrombosis, pulmonary embolism, and certain types of heart attacks. It can also be used during hemodialysis, cardiac bypass surgery, and other medical procedures to prevent the formation of blood clots.

It's important to note that while heparin is a powerful anticoagulant, it does not have any fibrinolytic activity, meaning it cannot dissolve existing blood clots. Instead, it prevents new clots from forming and stops existing clots from growing larger.

... also increases blood sugar levels.[citation needed] Dextran can be used in an ATPS for PEGylation Dextran is used in ... Resource on dextran properties and structure of dextran polymers Dextrans at the U.S. National Library of Medicine Medical ... Dextran has also been used in bead form to aid in bioreactor applications. Dextran has been used as an immobilization agent in ... Dextrans are available in multiple molecular weights ranging from 3 kDa to 2 MDa. The larger dextrans (>60,000 Da) are excreted ...
... is composed of a small fraction (1 kilodalton) of the entire dextran complex. This is enough to bind anti-dextran ... Thereby, dextran 1 binds up antibodies towards dextran without causing the immune response, leaving less antibodies left to ... Dextran 1 is a hapten inhibitor that greatly reduces the risk for anaphylactic reactions when administering dextran. ... Nine years of post-marketing surveillance of dextran 1". Annales Françaises d'Anesthésie et de Réanimation. 12 (2): 219-22. doi ...
... is a type of fluid given by injection into a vein to expand blood volume. Specifically it is used for shock such as ... Dextran 70 was approved for medical use in 1947. It is on the World Health Organization's List of Essential Medicines. It comes ... "Dextran 70". The American Society of Health-System Pharmacists. Archived from the original on 3 January 2017. Retrieved 8 ... "Dextran 70". Drug Information Portal. U.S. National Library of Medicine. Portal: Medicine (Infobox-drug molecular-weight ...
... is structurally different from acetylated dextran. Acetalated dextran was first reported in 2008 out of the ... Acetalated dextran's degradation time can vary from hours to a month or more at pH 7.2. Also, acetalated dextran is unique ... Acetalated dextran is a biodegradable polymer based on dextran that has acetal modified hydroxyl groups. After synthesis, the ... This version of acetalated dextran, often abbreviated Ac-DEX, has dextran and exceedingly low levels of acetone and methanol as ...
... s (BDA) are organic compounds used as anterograde and retrograde neuroanatomical tracers. They can be ... Reiner A, Veenman CL, Medina L, Jiao Y, Del Mar N, Honig MG (2000). "Pathway tracing using biotinylated dextran amines". J ...
Dextran microspheres are formulated in many forms including native dextran, dextran as a cross-linker, dextran conjugates, and ... One application of the glucose polymer dextran in microsphere compositions is as a cross-linker. Dextran and oxidized dextran ... Dextran-ECH hydrogels can be loaded with salmon calcitonin (sCT) to treat bone diseases. Dextran-ECH hydrogels loaded with sCT ... Dextran hydrogel and dextran conjugate hydrogel drug delivery systems have a variety of applications. These gels can be used to ...
Dextran+1,6-alpha-isomaltotriosidase at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Portal: Biology v ... Dextran 1,6-α-isomaltotriosidase (EC 3.2.1.95, exo-isomaltotriohydrolase, 1,6-α-D-glucan isomaltotriohydrolase) is an enzyme ... This enzyme catalyses the hydrolysis of (1→6)-α-D-glucosidic linkages in dextrans, to remove successive isomaltotriose units ...
Branched-dextran exo-1,2-α-glucosidase (EC 3.2.1.115, dextran 1,2-α-glucosidase, dextran α-1,2 debranching enzyme, 1,2-α-D- ... glucosyl-branched-dextran 2-glucohydrolase) is an enzyme with systematic name (1→2)-α-D-glucosyl-branched-dextran 2- ... Branched-dextran+exo-1,2-alpha-glucosidase at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Portal: ... It catalyses the hydrolysis of (1→2)-α-D-glucosidic linkages at the branch points of dextrans and related polysaccharides, ...
DEAE-Dextran (DEAE-D) is a positively charged dextran derivative that can be used for vaccine production, gene therapy, protein ... "DEAE-Dextran" (PDF). GE Life Sciences. Amersham Biosciences. Archived from the original (PDF) on 11 June 2016. Retrieved 11 May ... Cellulose, dextran, agarose, and other insoluble complexes are unaffected because they compose inert matrices, hence why they ... Gulick, Tod (2003). "Transfection Using DEAE-Dextran". Current Protocols in Cell Biology. 19: 20.4.1-20.4.10. doi:10.1002/ ...
Matsuda, Kazuo; H. Wanatabe; K. Fujimoto; K. Aso (1961). "Isolation of Nigerose and Kojibiose from Dextrans". Nature. 191 (4785 ... but is also readily extracted from the dextrans found in rice molds and many other fermenting microorganisms, such as L. ... Isolation of nigerose from the acetolysate of a dextran produced by Leuconostoc mesenteroides NRRL B-421". Tohoku Journal of ...
... is a cross-linked dextran gel used for gel filtration. It was launched by Pharmacia in 1959, after development work by ... The name is derived from separation Pharmacia dextran. It is normally manufactured in a bead form and most commonly used for ... Fractionation Range of Globular Proteins and Dextrans (Da). Ion-exchange chromatography. PEGylation Size exclusion ... filtration and chromatographic media are composed of macroscopic beads synthetically derived from the polysaccharide dextran. ...
Sawai T, Toriyama K, Yano K (January 1974). "A bacterial dextranase releasing only isomaltose from dextrans". Journal of ...
Dextran Pty Ltd - like Vaniro, another AdSteam subsidiary. Dextran is the owner of IEL. During the 1980s, AdSteam instigated a ... AdSteam investment company Dextran purchased IEL from Brierley Investments in November 1989. Dextran was one-third each owned ... and Dextran Pty Limited (1/3) which in turn owns Industrial Equity Limited." Metropolitan Wholesale Meat Company Limited ...
"Iron Dextran" Martindale: the Complete Drug Reference, by Sean C. Sweetman, Pharmaceutical Press, 2020. "Iron Dextran" AHFS ... Iron dextran is given by injection and should be used only in the treatment of proven iron-deficiency anemia where oral therapy ... Intravenous iron is administered directly to the bloodstream, in a form of iron carbohydrate complexes, such as iron dextran ...
Lopez, A; Monsan, P (1980). "Dextran synthesis by immobilized dextran sucrase". Biochimie. 62 (5-6): 323-329. doi:10.1016/S0300 ...
Whiteside, Catharine (1983). "Determination of glomerular permselectivity to neutral dextrans in the dog". American Journal of ...
The polymer dextran is one prominent example of a very useful polymer. It is produced at commercial scale for uses in ... Robyt JF, Yoon SH, Mukerjea R (December 2008). "Dextransucrase and the mechanism for dextran biosynthesis". Carbohydrate ...
Flodin worked with dextran research at Pharmacia. In 1957, Porath discovered that columns filled with dextran gel could be used ... A short time thereafter, Pharmacia offered the product Sephadex (Separation Pharmacia Dextran) on the market. Porath also ...
Hehre EJ, Hamilton DM (1953). "The biological synthesis of dextran from dextrins". J. Biol. Chem. 192: 161-174. Portal: Biology ... Other names in common use include dextrin 6-glucosyltransferase, and dextran dextrinase. Hehre EJ (1951). "Enzymic synthesis of ... "Bacterial conversion of dextrin into a polysaccharide with the serological properties of dextran". Proc. Soc. Exp. Biol. Med. ...
Dextran is a polysaccharide derived from bacteria; it is usually produced by enzymes from certain strains of leuconostoc or ... Cross-linked dextran hydrogel beads have been widely used as low protein-binding matrices for column chromatography ... However, it has not been until recently that dextran hydrogels have been investigated in biomaterials applications and ... An advantage of using dextran in biomaterials applications include its resistance to protein adsorption and cell-adhesion, ...
Experimental studies in rats using neutral dextran". Biophys. J. 15 (9): 887-906. Bibcode:1975BpJ....15..887C. doi:10.1016/ ...
Samples are mixed with 32% Dextran solution in HBSS. Centrifugation is performed at 4,400g for 20 minutes in order to separate ... Pellets are resuspended in a Dextran solution. A series of washes with PBS is performed to further decontaminate the pellet ...
Injectable forms include iron dextran and iron sucrose. They work by providing the iron needed for making red blood cells. Iron ... This has included dextrans, sucrose, carboxymaltose and more recently Isomaltoside 1000.[citation needed] One formulation of ... It is in complex with gluconate, dextran, carbonyl iron, and other salts. Ascorbic acid, vitamin C, increases the absorption of ... and the much safer low molecular iron dextrans (tradenames including Cosmofer and Infed). Iron sucrose has an occurrence of ...
"The Global Leader in Pharmaceutical Dextran , Pharmacosmos Dextran". www.dextran.com. Retrieved 2020-11-17. (Articles with ISNI ... It has a lower incidence of dextran-induced analphylaxis than older dextran-based products, although still requires a test dose ... The generic name for Uniferon is iron dextran. Its approved by health authorities in Europe, Asia and in the U.S. by Food and ... The generic name of Cosmofer is low molecular weight iron dextran. Cosmofer was approved in 2001, and is available in more than ...
"DER ARZNEIMITTELBRIEF: Infusionstherapie beim idiopathischen Hörsturz? Dextran Dextran Hörsturz Hydroxyethylstärke ...
Such polysaccharides include pectin, dextran, agar, and xanthan. Some of these carbohydrate polysaccharides are accessible for ...
... dextran sodium sulfate-induced colitis in mice; and 8) brain inflammation due to the reduction of blood flow to the brains of ...
LAB are able to synthesize levans from sucrose, and dextrans from glucose. Dextrans, like other glucan, enable bacteria to ...
"89Zr-Labeled Dextran Nanoparticles Allow in Vivo Macrophage Imaging". Bioconjugate Chemistry. 22 (12): 2383-9. doi:10.1021/ ...
Plasma expanders are natural or synthetic substances (dextran, albumin...), that are able to retain liquid in the vascular ...
Dextran also increases blood sugar levels.[citation needed] Dextran can be used in an ATPS for PEGylation Dextran is used in ... Resource on dextran properties and structure of dextran polymers Dextrans at the U.S. National Library of Medicine Medical ... Dextran has also been used in bead form to aid in bioreactor applications. Dextran has been used as an immobilization agent in ... Dextrans are available in multiple molecular weights ranging from 3 kDa to 2 MDa. The larger dextrans (>60,000 Da) are excreted ...
Iron Dextran Injection: learn about side effects, dosage, special precautions, and more on MedlinePlus ... Before receiving iron dextran injection,. *tell your doctor and pharmacist if you are allergic to iron dextran injection; any ... Iron dextran injection may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: * ... Iron dextran injection is used to treat iron-deficiency anemia (a lower than normal number of red blood cells due to too little ...
C6H10O5]n. CAS 9004-54-0. Browse Dextran and related products at Merck. ...
Detailed drug Information for Iron dextran. Includes common brand names, drug descriptions, warnings, side effects and dosing ... Iron dextran (Injection). Generic name: iron dextran [ EYE-urn-DEX-tran ]. Drug class: Iron products ... Detailed Iron dextran dosage information Precautions while using iron dextran. Your doctor will check your progress closely ... Uses for iron dextran. Iron dextran is an iron replacement product that is used to treat iron deficiency, such as anemia (not ...
FITC-Dextran; find Sigma-Aldrich-FD250S MSDS, related peer-reviewed papers, technical documents, similar products & more at ... Fluorescein isothiocyanate-dextran average mol wt 250,000; CAS Number: 60842-46-8; Synonyms: ... Native dextran has been found to have a molecular weight (MW) in the range of 9 million to 500 million. Lower MW dextrans will ... Dextrans with MW of 2,000 to 10,000, exhibit the properties of an expandable coil. At MW below 2,000, dextran is more rod-like ...
For dry eyes. Brand Name(s): Bion Tears. Generic Name: Dextran 70/Hydromellose.
Swelling of dextran gel and osmotic pressure of soluble dextran in the presence of salts. J. Polym. Sci. Pol. Phys. 39, 2740- ... High-resolution T1 MRI via renally clearable dextran nanoparticles with an iron oxide shell. *Tae-Hyun Shin1,2 na1, ... Shin, TH., Kim, P.K., Kang, S. et al. High-resolution T1 MRI via renally clearable dextran nanoparticles with an iron oxide ...
Dextran is naturally produced from Sucrose by some bacteria and occurs as slimes in fermenting vegetables and dairy products. ... Dextran is used in confections, lacquers and was formerly used in blood plasma. ... Retrieved from "https://cameo.mfa.org/index.php?title=Dextran&oldid=89781" ...
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Centers RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.. ...
Be the first to review "Dextran 75,000" Cancel reply. Your rating *. Rate…. Perfect. Good. Average. Not that bad. Very poor. ...
Mucrose;Glucose polymer;dextran11;dextran2;dextran5;DextrangradeA,B,C;dextrans;Dextraven;Ex-pandex;Gentran3;. ... China Dextran Suppliers ,offers quality China Dextran. ... Home > Offer to Sell > Intermediates > Dextran Dextran. Inquiry ...
Buy Sigma D8906-10G Dextran Sulfate Sodium Salt from Leuconostoc spp. for Molecular Biology, 10g Bottle ... Sigma D8906-10G Dextran Sulfate Sodium Salt from Leuconostoc spp. for Molecular Biology, 10g Bottle. Sigma-Aldrich D8906-10G ... Sigma D8906-10G Dextran Sulfate Sodium Salt from Leuconostoc spp. for Molecular Biology, 10g Bottle ... Molecular Weight: >500,000 (Dextran starting material), Contains 0.5-2% phosphate buffer. ...
CF® Dye Dextran 70,000 MW, Anionic and Fixable This dextran is 70,000 MW, and contains a formaldehyde-fixable free-amine group ... CF® Dye Dextran 70,000 MW. Conjugation. Ex/Em. Size. Catalog No.. Dye Features. ... CF® Dye labeled dextrans could be used as a fluorescent fluid-phase markers to study cell permeability, endocytosis, or ... The dextran is 70,000 MW, and contains a formaldehyde-fixable free-amine group. ...
Diffusion coefficient of 62kDa dextran in water. Value. 39 µm^2/sec Range: ±2.6 µm^2/sec ... The cytoplasmic translational diffusion coefficient DC and the nucleoplasmic diffusion coefficient DN of a 62-kd dextran were ... Fluorescence microphotolysis was used to measure nucleocytoplasmic flux in single rat hepatocytes for a series of dextrans ... Rate constant of Nucleo-cytoplasmic flux of 2.9 kDa dextran in cultured rat liver cells. ...
Experimentally, inflammation may be induced in mice by: 1) the addition of the chemical irritant dextran sulfate sodium (DSS) ... Effects of Dietary Bovine Lactoferrin on Intestinal Lymphocytes of Mice After Dextran Sulfate Sodium or Acute Exercise ... Paul Anthony Spagnuolo (2008). Effects of Dietary Bovine Lactoferrin on Intestinal Lymphocytes of Mice After Dextran Sulfate ...
Coagulation factor 9-deficient mice are protected against dextran sulfate sodium-induced colitis Avinash Khandagale, Avinash ... In the 3.5% dextran sulfate sodium (DSS)-induced colitis model, F9-deficient mice were protected from body-weight loss and had ... Here, we reveal in a dextran sulfate sodium (DSS) mouse model of acute intestinal inflammation, that F9-deficiency is ... RDP58, a locally active TNF inhibitor, is effective in the dextran sulphate mouse model of chronic colitis ...
Azoxymethane and dextran sulfate sodium-induced colitis associated cancer model. Specific pathogen free, 7-week-old C57BL/6 ... Melgar S, Karlsson L, Rehnström E, Karlsson A, Utkovic H, Jansson L, et al. Validation of murine dextran sulfate sodium-induced ... Dieleman LA, Palmen MJ, Akol H, Bloemena E, Peña AS, Meuwissen SG, et al. Chronic experimental colitis induced by dextran ... Figure 1: Histological images of the colonic mucosa of azoxymethane (AOM) and dextran sulfate sodium (DSS)-induced colitis ...
The iron content material of Fe3O4-dextran-anti-HCG nanoparticles is certainly 37.5 g/mL. Toxicity of Fe3O4-dextran-anti-HCG ... No cytotoxicity was noticed when the focus of Fe3O4-dextran-anti-HCG nanoparticles was 37.5 g/mL. Fe3O4-dextran nanoparticles ... Outcomes size and Morphology of Fe3O4-dextran-anti-HCG nanoparticles Fe3O4-dextran-anti-HCG nanoparticle option is Furosemide ... Fe3O4-dextran nanoparticles possess a reasonable potential to mix with -HCG antibody. by fabretpPosted on. January 12, 2022. ...
Dextran is labeled with fluorescein (FITC) through conjugation reaction of dextran amine and isothiocyanate of FITC, Ex/Em ...
CM-Dextran Fluorescein is a carboxymethyl (CM) Dextran labeled with fluorescein (FITC). Ex/Em wavelength 494/518 nm. Purity: , ... Degree of substitution: 1 mol % substitution and at least one dye molecule per dextran polymer. ...
Dextran, Etc.) Patents and Patent Applications (Class 436/529) Filed with the USPTO ... Dextran, Etc.) Patents (Class 436/529) Polysaccharide, Carrier (e.g., Dextran, Etc.) Patents (Class 436/529) ... In one embodiment, the nanocage is covalently attached to a polymer shell (e.g. a dextran shell). ...
Iron dextran is given in the vein (IV) or injection in a muscle (intramuscularly) and used to treat anemia. Find side effects, ... Iron dextran (INFeD). About This Drug. Iron dextran is used to treat anemia (low red blood cells) caused by low iron levels. It ...
Read Weilan gum oligosaccharide ameliorates dextran sulfate sodium‑induced experimental ulcerative colitis ... Weilan gum oligosaccharide ameliorates dextran sulfate sodium‑induced experimental ulcerative colitis Molecular Medicine ... Cryptotanshinone protects dextran sulfate sodium‐induced experimental ulcerative colitis in mice by inhibiting intestinal ... Study on the experimental ulcerative colitis model induced by dextran sulfate sodium in rats: Estimation of mucosal erosions by ...
Whereas conjugation of MP with dextran in both prodrugs substantially decreased the clearance of the drug by ∼200‐fold, the ... The plasma and tissue disposition of two novel dextran prodrugs of methylprednisolone (MP) containing one (DMP‐1) or five (DMP‐ ... The plasma and tissue disposition of two novel dextran prodrugs of methylprednisolone (MP) containing one (DMP‐1) or five (DMP‐ ... Whereas conjugation of MP with dextran in both prodrugs substantially decreased the clearance of the drug by ∼200‐fold, the ...
Dextran Sulfate, Sodium Salt, Molecular Biology Grade - CAS 9011-18-1 - Calbiochem Used to accelerate hybridization of DNA ... Dextran Sulfate, Sodium Salt, Molecular Biology Grade - CAS 9011-18-1 - Calbiochem Certificates of Analysis. Title. Lot Number ... Dextran Sulfate, Sodium Salt, Molecular Biology Grade - CAS 9011-18-1 - Calbiochem SDS. Title. ... 265152 MilliporeDextran Sulfate, Sodium Salt, Molecular Biology Grade - CAS 9011-18-1 - Calbiochem. ...
After pre-treatment with riboflavin 0.1%/dextran, mean thickness was 417.2µm (ranging 323 to 535) for RIBO eyes and 417.0µm ( ... Eyes were then randomized to receive either Riboflavin 0.1%/dextran (RIBO) or hypotonic (HYPO) riboflavin every 2 minutes for ... Kristen L. Fry, Steven A. Greenstein, Peter S. Hersh; Corneal Thickness Effects using Riboflavin/Dextran versus Hypotonic ... Purpose: : To investigate the use of Riboflavin 0.1% in 20% dextran solution versus its hypotonic formulation during ...
After polymerization and ultimate deprotection of the silylated dextran backbone, amphiphilic polyester-grafted dextrans were ... rst step of the synthesis of new amphiphilic polyester-grafted dextrans. According to the experimental conditions, i.e. dextran ... Whatever the dextran used, complete silylation of the polysaccharide chain could be achieved by adequate selection of the ... The partially silylated dextrans were ef®ciently used as multifunctional macroinitiators for the controlled ring-opening ...
When you visit dextran.com, we may collect and process the following personal data for the purposes mentioned below:. You sign ... Pharmacosmos is the only dextran manufacturer holding certificates from the US FDA and European Directorate for the Quality of ... I agree to receive updates via email from Pharmacosmos with insights related to Dextran application areas, new product ... Pharmacosmos delivers a unique dextran quality through a production technology that completely avoids the use of organic ...
Dextran 10 has traditionally been used in infusion fluid and volume expander products. ... Dextran has traditionally been used in infusion fluid and volume expander products. However, dextran has a very diverse ... Dextran 10 Synonyms:2,3,4,5-tetrahydroxy-6-[3,4,5-trihydroxy-6-[[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2- ... Quick Link: Dextran GMP manufacturer L-malic acid manufacturer Tirofiban manufacturer Large volume parenterals manufacturer ...
... against Dextran Sulfate Sodium (DSS) induced acute colitis in immunodeficient NOD.CB17-Prkdc scid/J mice with particular ... Induction of dextran sulfate sodium colitis in NOD.CB17-Prkdc scid/J mice. Twenty healthy NOD.CB17-Prkdc scid/J male mice, 7 to ... UCMSCs in dextran sulfate sodium (DSS)-treated mice were able to reduce the degree of DSS-induced colon shortening compared ... Action of dextran sulfate sodium in immunodeficient mice and role of administration of umbilical cord mesenchymal stem cells in ...
  • Dextran is a complex branched glucan (polysaccharide derived from the condensation of glucose), originally derived from wine. (wikipedia.org)
  • Whatever the dextran used, complete silylation of the polysaccharide chain could be achieved by adequate selection of the experimental conditions. (univ-lorraine.fr)
  • Dextran is a branched polysaccharide made of many glucose molecules joined into chains of varying lengths. (the-medical-dictionary.com)
  • Electrospinning of Dextran-Based Polysaccharide to Fabricate Nanofiber" by Andrea Bartus, Sabby Clemmons et al. (unh.edu)
  • Dextran is a complicating contaminant in the refining of sugar because it elevates the viscosity of sucrose solutions and fouls plumbing. (wikipedia.org)
  • Dextran is now produced from sucrose by certain lactic acid bacteria of the family lactobacillus. (wikipedia.org)
  • Dextran is naturally produced from Sucrose by some bacteria and occurs as slimes in fermenting vegetables and dairy products. (mfa.org)
  • Dextran is synthesized from sucrose by Leuconostoc mesenteroides streptococcus, and are also produced by bacteria and yeast. (the-medical-dictionary.com)
  • Dextran can be used as a stabilizing coating to protect metal nanoparticles from oxidation and improve biocompatibility. (wikipedia.org)
  • No cytotoxicity was noticed when the focus of Fe3O4-dextran-anti-HCG nanoparticles was 37.5 g/mL. (fabretp.org)
  • Agarose gel electrophoresis evaluation of binding tests demonstrated that after treatment with sodium periodate, Fe3O4-dextran-anti-HCG nanoparticles possess a reasonable potential to soak up DNA, as well as the protection test demonstrated that nanoparticles can secure DNA from DNase I digestion effectively. (fabretp.org)
  • Aldehyde Fe3O4-dextran-anti-HCG nanoparticles can transfect reporter genes, as well as the transfection performance of the nanoparticles is certainly higher than that of liposomes ( 0.05). (fabretp.org)
  • Fe3O4-dextran-anti-HCG nanoparticles can focus in choriocarcinoma cells and in transplanted choriocarcinoma tumors. (fabretp.org)
  • Conclusions: The outcomes concur that Fe3O4-dextran-anti-HCG nanoparticles possess potential being a protected, effective, and choriocarcinoma-specific concentrating on gene vector. (fabretp.org)
  • Outcomes size and Morphology of Fe3O4-dextran-anti-HCG nanoparticles Fe3O4-dextran-anti-HCG nanoparticle option is Furosemide atramentous and transparent. (fabretp.org)
  • Open up in another window Body 1 Transmitting electron micrograph of magnetic iron oxide (Fe3O4)-dextran-anti-HCG nanoparticles. (fabretp.org)
  • The iron content material of Fe3O4-dextran-anti-HCG nanoparticles is certainly 37.5 g/mL. (fabretp.org)
  • Toxicity of Fe3O4-dextran-anti-HCG nanoparticles As proven in Desk 1, the inhibitory price of nanoparticles at 56.25 and 75 g/mL is greater than control ( 0.05). (fabretp.org)
  • Desk 2 Transfection performance of anti-HCG monoclonal antibody destined to nanoparticle 0.05) (Desk 3), indicating that Fe3O4-dextran-anti-HCG nanoparticles work being a gene vector. (fabretp.org)
  • Oddly enough, the performance of gene transfection using Fe3O4-dextran-anti-HCG nanoparticles is certainly greater than that noticed using liposomes ( 0.05). (fabretp.org)
  • These results indicate that Fe3O4-dextran-anti-HCG nanoparticles are even more soaked up by choriocarcinoma cells readily. (fabretp.org)
  • A series of nanocomposite scaffolds comprised of dextran (Dex) and sol-gel derived bioactive glass ceramic nanoparticles (nBGC: 0-16 (wt%)) were fabricated as bioactive scaffolds for bone tissue engineering. (marquette.edu)
  • In-vitro and in-vivo assessment of dextran-appended cellulose acetate phthalate nanoparticles for transdermal delivery of 5-fluorouracil. (bvsalud.org)
  • The results showed that the optimized CAP nanoparticles (CNs) and dextran -coated CAP nanoparticles represented core-corona nanoparticles with the mean diameter of 75 ± 3 and 79 ± 2 nm, respectively, and entrapment efficiency was 82.5 ± 0.06 and 78.2 ± 0.12, respectively. (bvsalud.org)
  • Dextran -coated nanoparticles (FDCNs) and CAP nanoparticles (FCNs) showed in vitro 5-FU release upto 31 h and 8 h, respectively. (bvsalud.org)
  • Dextrans are available in multiple molecular weights ranging from 3 kDa to 2 MDa. (wikipedia.org)
  • Native dextran has been found to have a molecular weight (MW) in the range of 9 million to 500 million. (sigmaaldrich.com)
  • Avg. Molecular Weight: >500,000 (Dextran starting material), Contains 0.5-2% phosphate buffer. (capitolscientific.com)
  • Fluorescence microphotolysis was used to measure nucleocytoplasmic flux in single rat hepatocytes for a series of dextrans ranging in molecular mass from 3 to 150 kd. (harvard.edu)
  • The highest silylation yields were obtained with the lowest molecular weight dextrans. (univ-lorraine.fr)
  • It was observed that T g values of partially silylated dextran were maintained between 120 and 140 8C, independently of the dextran molecular weight. (univ-lorraine.fr)
  • Dextrans are available in multiple molecular weights ranging from 10,000 Da to 150,000 Da. (the-medical-dictionary.com)
  • Iron Dextran Injection is a sterile solution containing ferric hydroxide in complex with a low molecular weight dextran fraction equivalent to 100mg elemental iron per ml with 0.5% phenol as a preservative. (advacarepharma.com)
  • Outside of these features, larger dextrans, which do not pass out of the vessels, are potent osmotic agents, thus have been used urgently to treat hypovolemia[citation needed]. (wikipedia.org)
  • The larger dextrans (>60,000 Da) are excreted poorly from the kidney, so remain in the blood for as long as weeks until they are metabolized. (wikipedia.org)
  • The larger dextrans are excreted poorly from the kidney and therefore remain in the blood for as long as weeks until they are metabolized. (the-medical-dictionary.com)
  • Dextran labeled with fluorescein isothiocyanate for possible use in perfusion studies in animals. (sigmaaldrich.com)
  • Dextran is labeled with fluorescein (FITC) through conjugation reaction of dextran amine and isothiocyanate of FITC, Ex/Em wavelength 494/518 nm. (creativepegworks.com)
  • CM-Dextran Fluorescein is a carboxymethyl (CM) Dextran labeled with fluorescein (FITC). (creativepegworks.com)
  • This characteristic branching distinguishes a dextran from a dextrin, which is a straight chain glucose polymer tethered by α-1,4 or α-1,6 linkages. (wikipedia.org)
  • Dextran is a polymer of anhydroglucose. (sigmaaldrich.com)
  • Degree of substitution: 1 mol % substitution and at least one dye molecule per dextran polymer. (creativepegworks.com)
  • In one embodiment, the nanocage is covalently attached to a polymer shell (e.g. a dextran shell). (justia.com)
  • First, solutions of varying concentrations of dextran, a branched polymer of dextrose, were synthesized. (unh.edu)
  • FITC-dextran is used extensively in microcirculation and cell permeability research utilizing microfluorimetry. (sigmaaldrich.com)
  • FITC-dextran has been used to study plant cell wall porosity and capillary permeability. (sigmaaldrich.com)
  • Plasma proteins have been shown not to bind to FITC-dextran. (sigmaaldrich.com)
  • FITC-dextran is used in cardiovascular, microcirculation, perfusion, cell monolayer and cell membrane permeability research as fluorescent flux tracer compound that supports the measurement of processes such as blood flow, membrane damage, vascular drainage and renal elimination. (sigmaaldrich.com)
  • Small FITC-dextrans are also used to measure processes such as endocytosis. (sigmaaldrich.com)
  • FITC-Dextran 250 (FD 250) may be used as a model compound for development of methods to deliver molecules into protoplasts and to study drug release from structures such as hydrogels and liposomes. (sigmaaldrich.com)
  • Sigma typically tests the solubility of FITC dextrans in water at concentrations at or above 25 mg/ml. (sigmaaldrich.com)
  • In vivo, FITC-dextran is stable for more than 24 hours. (sigmaaldrich.com)
  • The functionality of the matured microvasculature networks was demonstrated through the enhancement of cell-cell adhesion, angiogenesis process, and perfusion tests with microparticles, FITC-dextran, and whole mouse blood. (lu.se)
  • Dextran in intravenous solution provides an osmotically neutral fluid that once in the body is digested by cells into glucose and free water. (the-medical-dictionary.com)
  • Sigma D8906-10G Dextran Sulfate Sodium Salt from Leuconostoc spp. (capitolscientific.com)
  • Dextran sulfate sodium is the sodium salt of dextran sulfate. (unipex.com)
  • Still, no difference has been detected in antithrombotic effectiveness in comparison of intra-arterial and intravenous administration of dextran. (wikipedia.org)
  • Close to 70% of dextran-40 is excreted in urine within the first 24 hours after intravenous infusion, while the remaining 30% are retained for several more days. (wikipedia.org)
  • and in certain intravenous fluids to solubilize other factors, such as iron (in a solution known as Iron Dextran). (wikipedia.org)
  • Intravenous solutions with dextran function both as volume expanders and means of parenteral nutrition. (wikipedia.org)
  • Still, no difference has been detected in antithrombotic effectiveness in comparison of intraaterial and intravenous administration of dextran. (the-medical-dictionary.com)
  • TRITC-lysine dextrans are synthesised from well-characterised dextran fractions derived from Leuconostoc mesenteroides. (tdblabs.se)
  • We deliver Pharmaceutical Quality Dextran of the highest standards, including those of the European Pharmacopoeia (EP), the United States Pharmacopoeia (USP), and the Japanese Pharmacopoeia (JP). (dextran.com)
  • The remaining (163) linkages account for the branching of dextran. (sigmaaldrich.com)
  • citation needed] Dextran can be used in an ATPS for PEGylation Dextran is used in the osmotic stress technique for applying osmotic pressure to biological molecules. (wikipedia.org)
  • Dextran coupled with a fluorescent molecule such as fluorescein isothiocyanate can be used to create concentration gradients of diffusible molecules for imaging and allow subsequent characterization of gradient slope. (wikipedia.org)
  • Dextrans with MW greater than 10,000 behave as if they are highly branched. (sigmaaldrich.com)
  • Dextrans with MW of 2,000 to 10,000, exhibit the properties of an expandable coil. (sigmaaldrich.com)
  • I agree to receive updates via email from Pharmacosmos with insights related to Dextran application areas, new product offerings and special offers. (dextran.kr)
  • The dextran fractions are first labelled with lysine and thereafter exposed to TRITC under mild conditions to form TRITC-lysine-dextran. (tdblabs.se)
  • Iron dextran injection may cause severe or life-threatening reactions while you receive the medication. (medlineplus.gov)
  • You will receive this medication in a medical facility and your doctor will watch you carefully during each dose of iron dextran injection. (medlineplus.gov)
  • Before you receive your first dose of iron dextran injection, your doctor will give you a test dose of medication and watch you carefully for at least 1 hour for any signs of an allergic reaction. (medlineplus.gov)
  • You may be at a higher risk of having an allergic reaction to iron dextran injection. (medlineplus.gov)
  • You should only receive iron dextran injection if you have a condition that cannot be treated with iron supplements that are taken by mouth. (medlineplus.gov)
  • Iron dextran injection is used to treat iron-deficiency anemia (a lower than normal number of red blood cells due to too little iron) in people who cannot be treated with iron supplements taken by mouth. (medlineplus.gov)
  • Iron dextran injection is in a class of medications called iron replacement products. (medlineplus.gov)
  • Iron dextran injection comes as a solution (liquid) to inject into the muscles of the buttocks or intravenously (into a vein) by a doctor or nurse in a medical facility. (medlineplus.gov)
  • Your doctor will determine how often you receive iron dextran injection and your total number of doses based on your weight, medical condition, and how well you respond to the medication. (medlineplus.gov)
  • You may experience a delayed reaction to iron dextran injection, beginning 24 to 48 hours after receiving a dose of medication and lasting for approximately 3 to 4 days. (medlineplus.gov)
  • or any of the ingredients in iron dextran injection. (medlineplus.gov)
  • AdvaCare Iron Dextran Liquid Injection is manufactured in our facilities located in China/India/USA. (advacarepharma.com)
  • It is important to note that AdvaCare's iron dextran injection is for veterinary purposes only, and altho' there are types similar medications for human use, you should only use medications prescribed by a veterinary doctor or animal care specialist for an animal. (advacarepharma.com)
  • As with all veterinary medicine, some unwanted effects can occur from the use of iron dextran injection. (advacarepharma.com)
  • Consult with an animal care specialist about any other medications that are being taken by the animal, and their medical history, before their treatment with iron dextran liquid injection. (advacarepharma.com)
  • Iron Dextran Uniferon is administered through intramuscular or subcutaneous injection. (entirelypetspharmacy.com)
  • The silylation reaction of dextran with 1,1,1,3,3,3-hexamethyldisilazane (HMDS) in DMSO was studied as the ®rst step of the synthesis of new amphiphilic polyester-grafted dextrans. (univ-lorraine.fr)
  • According to the experimental conditions, i.e. dextran molar weight, medium temperature and reaction time, HMDS/OH ratio, addition of a catalyst and co-solvent, partially or totally silylated dextrans were recovered. (univ-lorraine.fr)
  • Whereas conjugation of MP with dextran in both prodrugs substantially decreased the clearance of the drug by ∼200‐fold, the accumulations of the drug in the liver, spleen, and kidneys were significantly increased by conjugation. (uri.edu)
  • Dextran chains are of varying lengths (from 3 to 2000 kilodaltons). (wikipedia.org)
  • The aim of this research was transdermal delivery of 5-fluorouracil ( 5-FU ) using dextran -coated cellulose acetate phthalate (CAP) nanoparticulate formulation. (bvsalud.org)
  • The inhibitory effects of the doenjang prepared with the grain-type meju using mixed starter cultures were investigated in azoxymethane (AOM) and dextran sulfate sodium (DSS)-induced colon carcinogenesis mice model. (carcinogenesis.com)
  • In the present study we examined the protective potential of exogenously administered human umbilical cord derived mesenchymal stem cells (UCMSCs) against Dextran Sulfate Sodium (DSS) induced acute colitis in immunodeficient NOD.CB 17 - Prkdc scid /J mice with particular attention to endoplasmic reticulum (ER) stress. (biomedcentral.com)
  • fluorescent-labelled dextran can be used to visualize these endosomes under a microscope. (wikipedia.org)
  • TRITC-lysine-dextran is a dextran derivative carrying both free primary amines and free carboxylates as well as the fluorescent dye Tetramethylrhodamine (TRITC). (tdblabs.se)
  • Among the fluorescent calcium indicator dextran conjugates, Cal-520 dextran conjugates might be the best choice due to their high fluorescence quantum yield and large fluorescence enhancement by calcium. (aatbio.com)
  • The antithrombotic effect of dextran is mediated through its binding of erythrocytes, platelets, and vascular endothelium, increasing their electronegativity and thus reducing erythrocyte aggregation and platelet adhesiveness. (wikipedia.org)
  • Dextrans also reduce factor VIII-Ag Von Willebrand factor, thereby decreasing platelet function. (wikipedia.org)
  • The MW of dextran is measured by one or more of the following methods: low angle laser light scattering, size exclusion chromatography, copper-complexation and anthrone reagent colorometric reducing-end sugar determination and viscosity. (sigmaaldrich.com)
  • Compared to Oregon Green BAPTA-1 dextran, Cal-520 dextran exhibits much lower background and much larger calcium-induced fluorescence enhancement. (aatbio.com)
  • 1. Fluorescence intensity increase of Cal-520®-Dextran (Cat# 20600), Cal-520®-Dextran (Cat# 20601) and Calcium-Green™-1-Dextran upon binding saturated amount of calcium. (aatbio.com)
  • Solutions of fluorescently-labelled dextran can be perfused through engineered vessels to analyze vascular permeability Dextran is used to make microcarriers for industrial cell culture Orally-administered dextran sodium sulphate is used to induce colitis in animal models of inflammatory bowel disease. (wikipedia.org)
  • As the MW increases, dextran molecules attain greater symmetry. (sigmaaldrich.com)
  • After polymerization and ultimate deprotection of the silylated dextran backbone, amphiphilic polyester-grafted dextrans were readily recovered. (univ-lorraine.fr)
  • TRITC-lysine-dextran dissolves readily in water. (tdblabs.se)
  • AdvaCare is a GMP manufacturer of Iron Dextran liquid injections. (advacarepharma.com)
  • Always consult a veterinary doctor or animal care specialist before using iron dextran injections. (advacarepharma.com)
  • Anaphylactic-type reactions, including fatalities, have followed the parenteral use of iron dextran. (drugs.com)
  • Study on the experimental ulcerative colitis model induced by dextran sulfate sodium in rats: Estimation of mucosal erosions by the alcian blue-staining method. (sciencegate.app)
  • Study on the experimental ulcerative colitis(UC) model induced by dextran sulfate sodium(DSS) in rats. (sciencegate.app)
  • Use iron dextran only in patients no amenable to oral iron therapy. (drugs.com)
  • Iron dextran is an iron replacement product that is used to treat iron deficiency, such as anemia (not enough iron in the blood) or blood loss in patients with certain conditions (eg, hemophilia, gastrointestinal bleeding). (drugs.com)
  • Use of iron dextran is not recommended in children younger than 4 months of age. (drugs.com)
  • No information is available on the relationship of age to the effects of iron dextran in geriatric patients. (drugs.com)
  • However, elderly patients are more likely to have age-related liver, kidney, or heart problems, which may require caution in patients receiving iron dextran. (drugs.com)
  • Iron dextran is used to treat anemia (low red blood cells) caused by low iron levels. (upmc.com)
  • Iron Dextran Uniferon is a crucial addition to your livestock health management strategy. (entirelypetspharmacy.com)
  • With Iron Dextran Uniferon, you can enhance livestock growth and productivity, ensuring the health and performance of your animals. (entirelypetspharmacy.com)
  • The recommended dosage of Iron Dextran Uniferon may vary depending on the species, age, and weight of your livestock. (entirelypetspharmacy.com)
  • What is Iron Dextran Uniferon, and why is it important for livestock? (entirelypetspharmacy.com)
  • Iron Dextran Uniferon is an iron supplementation product used to combat anemia and enhance the overall health and performance of livestock. (entirelypetspharmacy.com)
  • The appropriate dosage of Iron Dextran Uniferon depends on factors like the species, age, and weight of your livestock. (entirelypetspharmacy.com)
  • Dextran was discovered by Louis Pasteur as a microbial product in wine, but mass production was only possible after the development by Allene Jeanes of a process using bacteria. (wikipedia.org)
  • Some bacteria coproduce fructans, which can complicate isolation of the dextrans. (wikipedia.org)
  • Dextran has traditionally been used in infusion fluid and volume expander products. (xawanlong.net)
  • TRITC-lysine-dextrans are supplied as a pink powder. (tdblabs.se)
  • TdB Labs produce TRITC-lysine-dextran from 4 kDa to 500 kDa. (tdblabs.se)
  • TRITC-lysine-dextran is stable for more than 6 years when stored dry in well-sealed containers at ambient temperature. (tdblabs.se)
  • TRITC-lysine-dextran is a versatile tool for bioconjugation and fixation in living systems. (tdblabs.se)
  • The structure of dextran produced depends not only on the family and species of the bacterium but on the strain. (wikipedia.org)
  • To investigate the use of Riboflavin 0.1% in 20% dextran solution versus its hypotonic formulation during ultraviolet light exposure in corneal collagen crosslinking (CXL) for keratoconus (KC) and ectasia. (arvojournals.org)
  • Interestingly, DMSO proved to behave as an ef®cient plasticizer of (partially) silylated dextrans. (univ-lorraine.fr)
  • The outcomes of this research will provide insights into the electrospinning process of dextran-based polysaccharides for fabricating nanofibers, and the characterization of resulting nanofibers and hydrogels. (unh.edu)
  • All eyes underwent pre-treatment with Riboflavin 0.1% in 20% dextran solution every 2 minutes for 30 minutes. (arvojournals.org)
  • 2021-09-27 9011-18-1 Dextran sulfate sodium Distributor. (kingcmx.com)
  • Although there are relatively few side-effects associated with dextran use, these side-effects can be very serious. (the-medical-dictionary.com)
  • Eyes were then randomized to receive either Riboflavin 0.1%/dextran (RIBO) or hypotonic (HYPO) riboflavin every 2 minutes for the 30 minute duration of UV exposure (UVA 365nm light for 30 minutes at an irradiance of 3mW/cm 2 ). (arvojournals.org)